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Y-Family DNA Polymerases Have Three Structural Elements That Promote Accurate dCTP Insertion And Minimize dATP/dGTP/dTTP Misinsertion Opposite a N 2 -dG Adduct of Benzo[ a ]pyrene
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/j.bbapap.2009.07.004openalex-snapshot
Variations on a theme: Eukaryotic Y-family DNA polymerases
inferredcites →https://doi.org/10.1016/j.bbapap.2010.01.020openalex-snapshot
Structural diversity of the Y-family DNA polymerases
inferredcites →https://doi.org/10.1016/j.dnarep.2003.11.012openalex-snapshot
A role for DNA polymerase V in G→T mutations from the major benzo[a]pyrene N2-dG adduct when studied in a 5′-TT sequence in E. coli
inferredcites →https://doi.org/10.1016/j.dnarep.2005.12.009openalex-snapshot
Mirror image stereoisomers of the major benzo[a]pyrene N2-dG adduct are bypassed by different lesion-bypass DNA polymerases in E. coli
inferredcites →https://doi.org/10.1016/j.dnarep.2013.05.006openalex-snapshot
Discrimination against major groove adducts by Y-family polymerases of the DinB subfamily
inferredcites →https://doi.org/10.1016/j.dnarep.2014.06.003openalex-snapshot
Mechanistic investigation of the bypass of a bulky aromatic DNA adduct catalyzed by a Y-family DNA polymerase
inferredcites →https://doi.org/10.1016/j.dnarep.2014.10.001openalex-snapshot
A method to accurately quantitate intensities of 32P-DNA bands when multiple bands appear in a single lane of a gel is used to study dNTP insertion opposite a benzo[a]pyrene-dG adduct by Sulfolobus DNA polymerases Dpo4 and Dbh
inferredcites →https://doi.org/10.1016/j.dnarep.2015.04.001openalex-snapshot
DNA polymerases: Biology, diseases and biomedical applications
inferredcites →https://doi.org/10.1016/j.dnarep.2015.09.020openalex-snapshot
How Y-Family DNA polymerase IV is more accurate than Dpo4 at dCTP insertion opposite an N2-dG adduct of benzo[a]pyrene
inferredcites →https://doi.org/10.1016/j.jmb.2008.03.038openalex-snapshot
Snapshots of a Y-Family DNA Polymerase in Replication: Substrate-induced Conformational Transitions and Implications for Fidelity of Dpo4
inferredcites →https://doi.org/10.1016/j.jmb.2009.07.016openalex-snapshot
Amino Acid Architecture That Influences dNTP Insertion Efficiency in Y-Family DNA Polymerase V of E. coli
inferredcites →https://doi.org/10.1016/j.jmb.2009.11.071openalex-snapshot
Effect of N2-Guanyl Modifications on Early Steps in Catalysis of Polymerization by Sulfolobus solfataricus P2 DNA Polymerase Dpo4 T239W
inferredcites →https://doi.org/10.1016/j.jmb.2011.11.038openalex-snapshot
Human DNA Polymerase η Is Pre-Aligned for dNTP Binding and Catalysis
inferredcites →https://doi.org/10.1016/j.jmb.2013.07.020openalex-snapshot
Structural Mechanism of Replication Stalling on a Bulky Amino-Polycyclic Aromatic Hydrocarbon DNA Adduct by a Y Family DNA Polymerase
inferredcites →https://doi.org/10.1016/j.jmgm.2005.10.009openalex-snapshot
Homology modeling of four Y-family, lesion-bypass DNA polymerases: The case that E. coli Pol IV and human Pol κ are orthologs, and E. coli Pol V and human Pol η are orthologs
inferredcites →https://doi.org/10.1016/j.jmgm.2006.05.003openalex-snapshot
Molecular modeling benzo[a]pyrene N2-dG adducts in the two overlapping active sites of the Y-family DNA polymerase Dpo4
inferredcites →https://doi.org/10.1016/j.jmgm.2008.11.003openalex-snapshot
Y-Family DNA polymerases may use two different dNTP shapes for insertion: A hypothesis and its implications
inferredcites →https://doi.org/10.1016/j.molcel.2007.01.018openalex-snapshot
Human DNA Polymerase κ Encircles DNA: Implications for Mismatch Extension and Lesion Bypass
inferredcites →https://doi.org/10.1016/j.str.2012.11.005openalex-snapshot
Y-Family Polymerase Conformation Is a Major Determinant of Fidelity and Translesion Specificity
inferredcites →https://doi.org/10.1016/j.str.2014.10.019openalex-snapshot
Unique Structural Features in DNA Polymerase IV Enable Efficient Bypass of the N 2 Adduct Induced by the Nitrofurazone Antibiotic
inferredcites →https://doi.org/10.1016/s0027-5107(03)00013-7openalex-snapshot
On the origin of G→T transversions in lung cancer
inferredcites →https://doi.org/10.1016/s0065-3233(04)69008-5openalex-snapshot
Properties and Functions of Escherichia Coli: Pol IV and Pol V
inferredcites →https://doi.org/10.1016/s0092-8674(01)00515-3openalex-snapshot
Crystal Structure of a Y-Family DNA Polymerase in Action
inferredcites →https://doi.org/10.1016/s0959-440x(02)00003-9openalex-snapshot
Damage repair DNA polymerases Y
inferredcites →https://doi.org/10.1016/s1097-2765(01)00306-9openalex-snapshot
Structure of the Catalytic Core of S. cerevisiae DNA Polymerase η
inferredcites →https://doi.org/10.1016/s1097-2765(01)00310-0openalex-snapshot
Crystal Structure of a DinB Lesion Bypass DNA Polymerase Catalytic Fragment Reveals a Classic Polymerase Catalytic Domain
inferredcites →https://doi.org/10.1016/s1383-5742(00)00047-8openalex-snapshot
Factors that influence the mutagenic patterns of DNA adducts from chemical carcinogens
inferredcites →https://doi.org/10.1016/s1568-7864(02)00055-1openalex-snapshot
Activities of human DNA polymerase κ in response to the major benzo[a]pyrene DNA adduct: error-free lesion bypass and extension synthesis from opposite the lesion
inferredcites →https://doi.org/10.1021/bi00007a020openalex-snapshot
The Major, N2-Gua Adduct of the (+)-anti-Benzo[a]pyrenediol Epoxide Can Be Unstable in Double-Stranded DNA
inferredcites →https://doi.org/10.1021/bi00058a009openalex-snapshot
Mutagenesis by the (+)-anti-diol epoxide of benzo[a]pyrene: What controls mutagenic specificity?
inferredcites →https://doi.org/10.1021/bi00489a001openalex-snapshot
Additivity of mutational effects in proteins
inferredcites →https://doi.org/10.1021/bi020049copenalex-snapshot
Translesion Synthesis by Human DNA Polymerase κ on a DNA Template Containing a Single Stereoisomer of dG-(+)- or dG-(−)-anti-N2-BPDE (7,8-Dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene)
inferredcites →https://doi.org/10.1021/bi026912qopenalex-snapshot
Effects of Base Sequence Context on Translesion Synthesis Past a Bulky (+)-trans-anti-B[a]P-N2-dG Lesion Catalyzed by the Y-family Polymerase pol κ
inferredcites →https://doi.org/10.1021/bi500019sopenalex-snapshot
An Overview of Y-Family DNA Polymerases and a Case Study of Human DNA Polymerase η
inferredcites →https://doi.org/10.1021/bi5007964openalex-snapshot
Structural and Dynamic Characterization of Polymerase κ’s Minor Groove Lesion Processing Reveals How Adduct Topology Impacts Fidelity
inferredcites →https://doi.org/10.1021/ja068821copenalex-snapshot
A Water-Mediated and Substrate-Assisted Catalytic Mechanism forSulfolobus solfataricusDNA Polymerase IV
inferredcites →https://doi.org/10.1021/jacs.5b08027openalex-snapshot
Mechanistic Basis for the Bypass of a Bulky DNA Adduct Catalyzed by a Y-Family DNA Polymerase
inferredcites →https://doi.org/10.1021/tx9000489openalex-snapshot
Chemistry and Biology of DNA Containing 1,N2-Deoxyguanosine Adducts of the α,β-Unsaturated Aldehydes Acrolein, Crotonaldehyde, and 4-Hydroxynonenal
inferredcites →https://doi.org/10.1038/cr.2008.4openalex-snapshot
The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases
inferredcites →https://doi.org/10.1038/nature04318openalex-snapshot
A single amino acid governs enhanced activity of DinB DNA polymerases on damaged templates
inferredcites →https://doi.org/10.1038/nature09104openalex-snapshot
Structural basis for the suppression of skin cancers by DNA polymerase η
inferredcites →https://doi.org/10.1038/nature09196openalex-snapshot
Structure and mechanism of human DNA polymerase η
inferredcites →https://doi.org/10.1038/nsmb.1771openalex-snapshot
Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4
inferredcites →https://doi.org/10.1038/nsmb1118openalex-snapshot
Hoogsteen base pair formation promotes synthesis opposite the 1,N6-ethenodeoxyadenosine lesion by human DNA polymerase ι
inferredcites →https://doi.org/10.1046/j.1365-2958.2000.02116.xopenalex-snapshot
The processing of a Benzo(a)pyrene adduct into a frameshift or a base substitution mutation requires a different set of genes in Escherichia coli
inferredcites →https://doi.org/10.1073/pnas.0308332100openalex-snapshot
Crystal structure of a benzo[ a ]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase
inferredcites →https://doi.org/10.1073/pnas.0700717104openalex-snapshot
A structural gap in Dpo4 supports mutagenic bypass of a major benzo[ a ]pyrene dG adduct in DNA through template misalignment
inferredcites →https://doi.org/10.1073/pnas.0711546105openalex-snapshot
Efficient and accurate bypass of N 2 -(1-carboxyethyl)-2′-deoxyguanosine by DinB DNA polymerase in vitro and in vivo
inferredcites →https://doi.org/10.1073/pnas.1324168111openalex-snapshot
Variants of mouse DNA polymerase κ reveal a mechanism of efficient and accurate translesion synthesis past a benzo[ a ]pyrene dG adduct
inferredcites →https://doi.org/10.1073/pnas.222377899openalex-snapshot
Polκ protects mammalian cells against the lethal and mutagenic effects of benzo[ a ]pyrene
inferredcites →https://doi.org/10.1073/pnas.97.8.3838openalex-snapshot
The human DINB1 gene encodes the DNA polymerase Polθ
inferredcites →https://doi.org/10.1074/jbc.m109.009506openalex-snapshot
Conformational Changes during Nucleotide Selection by Sulfolobus solfataricus DNA Polymerase Dpo4
inferredcites →https://doi.org/10.1074/jbc.m109.014274openalex-snapshot
Structure-Function Relationships in Miscoding by Sulfolobus solfataricus DNA Polymerase Dpo4
inferredcites →https://doi.org/10.1074/jbc.m109.037259openalex-snapshot
Translesional DNA Synthesis through a C8-Guanyl Adduct of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Vitro
inferredcites →https://doi.org/10.1074/jbc.m109575200openalex-snapshot
Efficiency and Accuracy of SOS-induced DNA Polymerases Replicating Benzo[a]pyrene-7,8-diol 9,10-Epoxide A and G Adducts
inferredcites →https://doi.org/10.1074/jbc.m113.537860openalex-snapshot
Three Residues of the Interdomain Linker Determine the Conformation and Single-base Deletion Fidelity of Y-family Translesion Polymerases
inferredcites →https://doi.org/10.1074/jbc.m201167200openalex-snapshot
trans-Lesion Synthesis Past Bulky Benzo[a]pyrene Diol Epoxide N2-dG and N6-dA Lesions Catalyzed by DNA Bypass Polymerases
inferredcites →https://doi.org/10.1074/jbc.m206027200openalex-snapshot
Human DNA Polymerase κ Bypasses and Extends beyond Thymine Glycols during Translesion Synthesis in Vitro, Preferentially Incorporating Correct Nucleotides
inferredcites →https://doi.org/10.1074/jbc.m405249200openalex-snapshot
Investigating the Role of the Little Finger Domain of Y-family DNA Polymerases in Low Fidelity Synthesis and Translesion Replication
inferredcites →https://doi.org/10.1074/jbc.m409155200openalex-snapshot
Quantitative Analysis of Translesion DNA Synthesis across a Benzo[a]pyrene-Guanine Adduct in Mammalian Cells
inferredcites →https://doi.org/10.1074/jbc.m801238200openalex-snapshot
Role for DNA Polymerase κ in the Processing of N2-N2-Guanine Interstrand Cross-links
inferredcites →https://doi.org/10.1080/00304949709355197openalex-snapshot
BRIDGED POLYCYCLIC AROMATIC HYDROCARBONS. A REVIEW
inferredcites →https://doi.org/10.1093/emboj/19.22.6259openalex-snapshot
All three SOS‐inducible DNA polymerases (Pol II, Pol IV and Pol V) are involved in induced mutagenesis
inferredcites →https://doi.org/10.1093/mutage/gei061openalex-snapshot
Mutagenesis studies with four stereoisomeric N2-dG benzo[a]pyrene adducts in the identical 5′-CGC sequence used in NMR studies: G→T mutations dominate in each case
inferredcites →https://doi.org/10.1093/nar/gkn719openalex-snapshot
The N-clasp of human DNA polymerase κ promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesions
inferredcites →https://doi.org/10.1093/nar/gks1296openalex-snapshot
Replication of a carcinogenic nitropyrene DNA lesion by human Y-family DNA polymerase
inferredcites →https://doi.org/10.1093/nar/gkt146openalex-snapshot
A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli
inferredcites →https://doi.org/10.1093/nar/gkv1067openalex-snapshot
Mechanism of aromatic amine carcinogen bypass by the Y-family polymerase, Dpo4
inferredcites →https://doi.org/10.1093/nar/gkw204openalex-snapshot
Structure and mechanism of error-free replication past the major benzo[a]pyrene adduct by human DNA polymerase κ
inferredcites →https://doi.org/10.1111/febs.13304openalex-snapshot
Noncognate DNA damage prevents the formation of the active conformation of the Y‐family DNA polymerases DinB and DNA polymerase κ
inferredcites →https://doi.org/10.1111/j.1365-2443.2005.00858.xopenalex-snapshot
Error‐prone and inefficient replication across 8‐hydroxyguanine (8‐oxoguanine) in human and mouse ras gene fragments by DNA polymerase κ
inferredcites →https://doi.org/10.1371/journal.pbio.0040011openalex-snapshot
Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion
inferredcites →https://doi.org/10.4061/2010/784081openalex-snapshot
Architecture of Y‐Family DNA Polymerases Relevant to Translesion DNA Synthesis as Revealed in Structural and Molecular Modeling Studies
inferredcites →https://doi.org/10.4061/2010/830473openalex-snapshot
Mechanistic Studies with DNA Polymerases Reveal Complex Outcomes following Bypass of DNA Damage
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