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Deep learning of representations for transcriptomics-based phenotype prediction

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/978-1-4757-3462-1openalex-snapshot
Regression Modeling Strategies
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Bioinformatics Approaches to Predict Drug Responses from Genomic Sequencing
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Measurement of mRNA abundance using RNA-seq data: RPKM measure is inconsistent among samples
inferredcites →https://doi.org/10.1016/j.cell.2018.02.052openalex-snapshot
An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics
inferredcites →https://doi.org/10.1016/j.immuni.2014.04.019openalex-snapshot
Activation of the Aryl Hydrocarbon Receptor Dampens the Severity of Inflammatory Skin Conditions
inferredcites →https://doi.org/10.1016/j.jaci.2015.03.003openalex-snapshot
RNA sequencing atopic dermatitis transcriptome profiling provides insights into novel disease mechanisms with potential therapeutic implications
inferredcites →https://doi.org/10.1016/s1672-0229(06)60022-3openalex-snapshot
Improve Survival Prediction Using Principal Components of Gene Expression Data
inferredcites →https://doi.org/10.1021/acs.molpharmaceut.5b00982openalex-snapshot
Applications of Deep Learning in Biomedicine
inferredcites →https://doi.org/10.1038/75556openalex-snapshot
Gene Ontology: tool for the unification of biology
inferredcites →https://doi.org/10.1038/nbt.2702openalex-snapshot
Reproducibility of high-throughput mRNA and small RNA sequencing across laboratories
inferredcites →https://doi.org/10.1038/nbt.3000openalex-snapshot
Detecting and correcting systematic variation in large-scale RNA sequencing data
inferredcites →https://doi.org/10.1038/nbt.3838openalex-snapshot
Reproducible RNA-seq analysis using recount2
inferredcites →https://doi.org/10.1038/ncomms13427openalex-snapshot
In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development
inferredcites →https://doi.org/10.1038/ng.2653openalex-snapshot
The Genotype-Tissue Expression (GTEx) project
inferredcites →https://doi.org/10.1038/nmeth.1439openalex-snapshot
Cell type–specific gene expression differences in complex tissues
inferredcites →https://doi.org/10.1038/s41467-018-03751-6openalex-snapshot
Massive mining of publicly available RNA-seq data from human and mouse
inferredcites →https://doi.org/10.1038/s41592-018-0229-2openalex-snapshot
Deep generative modeling for single-cell transcriptomics
inferredcites →https://doi.org/10.1038/s41598-018-19635-0openalex-snapshot
Robust phenotype prediction from gene expression data using differential shrinkage of co-regulated genes
inferredcites →https://doi.org/10.1053/j.gastro.2015.10.041openalex-snapshot
Association Between Response to Etrolizumab and Expression of Integrin αE and Granzyme A in Colon Biopsies of Patients With Ulcerative Colitis
inferredcites →https://doi.org/10.1073/pnas.0506580102openalex-snapshot
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
inferredcites →https://doi.org/10.1073/pnas.1402665111openalex-snapshot
Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism
inferredcites →https://doi.org/10.1080/01621459.1977.10480613openalex-snapshot
The Efficiency of Cox's Likelihood Function for Censored Data
inferredcites →https://doi.org/10.1093/bioinformatics/btaa293openalex-snapshot
scVAE: variational auto-encoders for single-cell gene expression data
inferredcites →https://doi.org/10.1093/bioinformatics/btt351openalex-snapshot
CellMix: a comprehensive toolbox for gene expression deconvolution
inferredcites →https://doi.org/10.1093/bioinformatics/btt432openalex-snapshot
TFcheckpoint: a curated compendium of specific DNA-binding RNA polymerase II transcription factors
inferredcites →https://doi.org/10.1093/bioinformatics/btt703openalex-snapshot
Causal analysis approaches in Ingenuity Pathway Analysis
inferredcites →https://doi.org/10.1093/bioinformatics/btu272openalex-snapshot
Robust clinical outcome prediction based on Bayesian analysis of transcriptional profiles and prior causal networks
inferredcites →https://doi.org/10.1093/nar/gks1193openalex-snapshot
NCBI GEO: archive for functional genomics data sets—update
inferredcites →https://doi.org/10.1093/nar/gkv1351openalex-snapshot
The Reactome pathway Knowledgebase
inferredcites →https://doi.org/10.1093/nar/gkx1132openalex-snapshot
The Reactome Pathway Knowledgebase
inferredcites →https://doi.org/10.1093/nar/gky102openalex-snapshot
Improving the value of public RNA-seq expression data by phenotype prediction
inferredcites →https://doi.org/10.1097/mib.0000000000000478openalex-snapshot
MicroRNAs Classify Different Disease Behavior Phenotypes of Crohnʼs Disease and May Have Prognostic Utility
inferredcites →https://doi.org/10.1098/rsif.2017.0387openalex-snapshot
Opportunities and obstacles for deep learning in biology and medicine
inferredcites →https://doi.org/10.1101/278739openalex-snapshot
DeepProfile: Deep learning of cancer molecular profiles for precision medicine
inferredcites →https://doi.org/10.1101/299107openalex-snapshot
Who is this gene and what does it do? A toolkit for munging transcriptomics data in python
inferredcites →https://doi.org/10.1109/allerton.2012.6483308openalex-snapshot
Stochastic optimization for PCA and PLS
inferredcites →https://doi.org/10.1109/bibm.2015.7359871openalex-snapshot
Learning structure in gene expression data using deep architectures, with an application to gene clustering
inferredcites →https://doi.org/10.1111/j.2517-6161.1982.tb01195.xopenalex-snapshot
The Statistical Analysis of Compositional Data
inferredcites →https://doi.org/10.1142/9789813235533_0008openalex-snapshot
Extracting a biologically relevant latent space from cancer transcriptomes with variational autoencoders
inferredcites →https://doi.org/10.1186/1471-2105-12-323openalex-snapshot
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
inferredcites →https://doi.org/10.1186/1471-2105-12-449openalex-snapshot
ReCount: A multi-experiment resource of analysis-ready RNA-seq gene count datasets
inferredcites →https://doi.org/10.1186/2049-2618-2-15openalex-snapshot
Unifying the analysis of high-throughput sequencing datasets: characterizing RNA-seq, 16S rRNA gene sequencing and selective growth experiments by compositional data analysis
inferredcites →https://doi.org/10.1186/gm214openalex-snapshot
Gene expression deconvolution in clinical samples
inferredcites →https://doi.org/10.1186/s12859-016-1311-3openalex-snapshot
Integrating gene set analysis and nonlinear predictive modeling of disease phenotypes using a Bayesian multitask formulation
inferredcites →https://doi.org/10.1186/s12859-017-1984-2openalex-snapshot
A biological network-based regularized artificial neural network model for robust phenotype prediction from gene expression data
inferredcites →https://doi.org/10.1186/s13073-015-0208-5openalex-snapshot
Proteogenomic analysis of psoriasis reveals discordant and concordant changes in mRNA and protein abundance
inferredcites →https://doi.org/10.1214/aoms/1177730491openalex-snapshot
On a Test of Whether one of Two Random Variables is Stochastically Larger than the Other
inferredcites →https://doi.org/10.1371/journal.pcbi.1004075openalex-snapshot
Proportionality: A Valid Alternative to Correlation for Relative Data
inferredcites →https://doi.org/10.18653/v1/k16-1002openalex-snapshot
Generating Sentences from a Continuous Space
inferredcites →https://doi.org/10.4230/oasics.dx.2026.15openalex-snapshot
AutoResearch Lite: a reproducible paper-inspired experiment runner (Adam mechanism reproduction and convergence-speed comparison)
inferredcites →https://doi.org/10.48550/arxiv.1201.0490openalex-snapshot
Scikit-learn: Machine Learning in Python
inferredcites →https://doi.org/10.48550/arxiv.1312.6114openalex-snapshot
Auto-Encoding Variational Bayes
inferredcites →https://doi.org/10.48550/arxiv.1412.6980openalex-snapshot
Adam: A Method for Stochastic Optimization
inferredcites →https://doi.org/10.48550/arxiv.1706.02515openalex-snapshot
Self-Normalizing Neural Networks
inferredcites →https://doi.org/10.48550/arxiv.1706.08203openalex-snapshot
Dr.VAE: Drug Response Variational Autoencoder
inferredcites →https://doi.org/10.48550/arxiv.1711.04828openalex-snapshot
Evaluating deep variational autoencoders trained on pan-cancer gene expression
inferredcites →https://doi.org/10.57702/o9raffedopenalex-snapshot
Batch Normalization: Accelerating Deep Network Training by Reducing Internal Covariate Shift

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.tips.2019.06.003openalex-snapshot
Insights into Computational Drug Repurposing for Neurodegenerative Disease
inferred← citeshttps://doi.org/10.1101/653907openalex-snapshot
Deep learning does not outperform classical machine learning for cell-type annotation
inferred← citeshttps://doi.org/10.1109/access.2019.2947687openalex-snapshot
An End-to-End-Based Low Dimensional Binary Embedding for Chrysanthemum Phenotypic Petal Similarity Evaluation
inferred← citeshttps://doi.org/10.2174/0118715273329531240911075309openalex-snapshot
Revolutionising Neurological Therapeutics: Investigating Drug Repurposing Strategies
inferred← citeshttps://doi.org/10.3389/fphar.2022.1007315openalex-snapshot
Therapeutic drug repositioning with special emphasis on neurodegenerative diseases: Threats and issues
inferred← citeshttps://doi.org/10.3390/app9153065openalex-snapshot
Occam’s Razor for Big Data? On Detecting Quality in Large Unstructured Datasets
inferred← citeshttps://doi.org/10.3390/ijms22020840openalex-snapshot
Application of Machine-Learning Methods to Recognize mitoBK Channels from Different Cell Types Based on the Experimental Patch-Clamp Results
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