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Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

https://doi.org/10.1101/592899
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1006/exnr.1993.1214openalex-snapshot
Glial Cell Line-Derived Neurotrophic Factor Is Expressed in the Developing but Not Adult Striatum and Stimulates Developing Dopamine Neurons in Vivo
inferredcites →https://doi.org/10.1016/j.ajhg.2010.11.011openalex-snapshot
GCTA: A Tool for Genome-wide Complex Trait Analysis
inferredcites →https://doi.org/10.1016/j.ajhg.2014.12.006openalex-snapshot
Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder
inferredcites →https://doi.org/10.1016/j.cell.2018.05.046openalex-snapshot
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
inferredcites →https://doi.org/10.1016/s0140-6736(12)62129-1openalex-snapshot
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
inferredcites →https://doi.org/10.1038/ng.2711openalex-snapshot
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
inferredcites →https://doi.org/10.1038/ng.3406openalex-snapshot
An atlas of genetic correlations across human diseases and traits
inferredcites →https://doi.org/10.1038/ng.3538openalex-snapshot
Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
inferredcites →https://doi.org/10.1038/s41467-017-01261-5openalex-snapshot
Functional mapping and annotation of genetic associations with FUMA
inferredcites →https://doi.org/10.1038/s41467-017-02317-2openalex-snapshot
Causal associations between risk factors and common diseases inferred from GWAS summary data
inferredcites →https://doi.org/10.1038/s41467-018-04558-1openalex-snapshot
Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood
inferredcites →https://doi.org/10.1038/s41588-017-0009-4openalex-snapshot
Multi-trait analysis of genome-wide association summary statistics using MTAG
inferredcites →https://doi.org/10.1038/s41588-018-0059-2openalex-snapshot
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
inferredcites →https://doi.org/10.1038/s41588-018-0090-3openalex-snapshot
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
inferredcites →https://doi.org/10.1038/s41588-018-0129-5openalex-snapshot
Genetic identification of brain cell types underlying schizophrenia
inferredcites →https://doi.org/10.1038/s41588-018-0269-7openalex-snapshot
Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder
inferredcites →https://doi.org/10.1038/s41588-019-0344-8openalex-snapshot
Identification of common genetic risk variants for autism spectrum disorder
inferredcites →https://doi.org/10.1038/s41588-019-0397-8openalex-snapshot
Genome-wide association study identifies 30 loci associated with bipolar disorder
inferredcites →https://doi.org/10.1093/bioinformatics/btw613openalex-snapshot
LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis
inferredcites →https://doi.org/10.1093/oxfordjournals.aje.a115184openalex-snapshot
THE ATHEROSCLEROSIS RISK IN COMMUNIT (ARIC) STUDY: DESIGN AND OBJECTIVES
inferredcites →https://doi.org/10.1101/118810openalex-snapshot
MTAG: Multi-Trait Analysis of GWAS
inferredcites →https://doi.org/10.1101/224774openalex-snapshot
Common risk variants identified in autism spectrum disorder
inferredcites →https://doi.org/10.1101/gad.14.10.1169openalex-snapshot
Cadherin superfamily genes: functions, genomic organization, and neurologic diversity
inferredcites →https://doi.org/10.1126/science.8493557openalex-snapshot
GDNF: a Glial Cell Line-Derived Neurotrophic Factor for Midbrain Dopaminergic Neurons
inferredcites →https://doi.org/10.1186/s13059-016-1041-xopenalex-snapshot
An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation
inferredcites →https://doi.org/10.1192/bjp.bp.112.110858openalex-snapshot
Clinical staging in psychiatry: a cross-cutting model of diagnosis with heuristic and practical value
inferredcites →https://doi.org/10.1242/dev.123737openalex-snapshot
The retromer complex in development and disease
inferredcites →https://doi.org/10.1371/journal.pcbi.1004219openalex-snapshot
MAGMA: Generalized Gene-Set Analysis of GWAS Data

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1007/s00115-019-0745-zopenalex-snapshot
Molekulargenetische Erkenntnisse erweitern das Verständnis psychiatrischer Störungen
inferred← citeshttps://doi.org/10.1038/s41386-020-00847-wopenalex-snapshot
Investigation of glycaemic traits in psychiatric disorders using Mendelian randomisation revealed a causal relationship with anorexia nervosa
inferred← citeshttps://doi.org/10.1038/s41398-021-01493-6openalex-snapshot
Transcriptional-regulatory convergence across functional MDD risk variants identified by massively parallel reporter assays
inferred← citeshttps://doi.org/10.1038/s41467-019-13544-0openalex-snapshot
Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent
inferred← citeshttps://doi.org/10.1038/s41588-021-00787-1openalex-snapshot
Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS
inferred← citeshttps://doi.org/10.1126/sciadv.abj8969openalex-snapshot
Genetic estimates of correlation and causality between blood-based biomarkers and psychiatric disorders
inferred← citeshttps://doi.org/10.1186/s12888-020-02883-8openalex-snapshot
Understanding the nature of association between anxiety phenotypes and anorexia nervosa: a triangulation approach
inferred← citeshttps://doi.org/10.3390/brainsci11010047openalex-snapshot
Phenomenology, Epidemiology and Aetiology of Postpartum Psychosis: A Review
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