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A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank
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1 of the 64 references listed on this page is in the Retraction Watch database as retracted (export 2026-11-11): 10.1192/bjo.2018.12 (notice 2019-06-17).
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1001/jamapsychiatry.2015.0071openalex-snapshot
Large-Scale Network Dysfunction in Major Depressive Disorder
inferredcites →https://doi.org/10.1001/jamapsychiatry.2015.3457openalex-snapshot
The Course of Illness After Initial Diagnosis of Major Depression
inferredcites →https://doi.org/10.1002/0471667196.ess0866.pub2openalex-snapshot
Generalized Linear Models
inferredcites →https://doi.org/10.1002/ajmg.b.32221openalex-snapshot
Arguments for the sake of endophenotypes: Examining common misconceptions about the use of endophenotypes in psychiatric genetics
inferredcites →https://doi.org/10.1002/wps.20252openalex-snapshot
Risk of metabolic syndrome and its components in people with schizophrenia and related psychotic disorders, bipolar disorder and major depressive disorder: a systematic review and meta‐analysis
inferredcites →https://doi.org/10.1016/j.biopsych.2011.08.022openalex-snapshot
High Dimensional Endophenotype Ranking in the Search for Major Depression Risk Genes
inferredcites →https://doi.org/10.1016/j.bpsc.2018.06.007openalex-snapshot
Resting-State Connectivity and Its Association With Cognitive Performance, Educational Attainment, and Household Income in the UK Biobank
inferredcites →https://doi.org/10.1016/j.neuroimage.2017.07.014openalex-snapshot
Investigations into within- and between-subject resting-state amplitude variations
inferredcites →https://doi.org/10.1016/j.neuroimage.2017.10.034openalex-snapshot
Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank
inferredcites →https://doi.org/10.1016/j.neuron.2014.01.027openalex-snapshot
The Genetics of Major Depression
inferredcites →https://doi.org/10.1016/j.neuron.2017.12.018openalex-snapshot
Statistical Challenges in “Big Data” Human Neuroimaging
inferredcites →https://doi.org/10.1016/j.tins.2008.06.006openalex-snapshot
The HPA axis in major depression: classical theories and new developments
inferredcites →https://doi.org/10.1016/j.tins.2015.08.001openalex-snapshot
Depression as a Microglial Disease
inferredcites →https://doi.org/10.1016/s0140-6736(17)32802-7openalex-snapshot
Comparative Efficacy and Acceptability of 21 Antidepressant Drugs for the Acute Treatment of Adults With Major Depressive Disorder: A Systematic Review and Network Meta-Analysis
inferredcites →https://doi.org/10.1016/s2215-0366(15)00505-2openalex-snapshot
Estimating the true global burden of mental illness
inferredcites →https://doi.org/10.1016/s2542-5196(18)30051-2openalex-snapshot
Residential greenness and prevalence of major depressive disorders: a cross-sectional, observational, associational study of 94 879 adult UK Biobank participants
inferredcites →https://doi.org/10.1038/35036228openalex-snapshot
The prefontral cortex and cognitive control
inferredcites →https://doi.org/10.1038/mp.2015.225openalex-snapshot
Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia
inferredcites →https://doi.org/10.1038/mp.2015.69openalex-snapshot
Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group
inferredcites →https://doi.org/10.1038/mp.2015.86openalex-snapshot
Polygenic dissection of major depression clinical heterogeneity
inferredcites →https://doi.org/10.1038/nature10524openalex-snapshot
Temporal dynamics and genetic control of transcription in the human prefrontal cortex
inferredcites →https://doi.org/10.1038/ng.3623openalex-snapshot
Identification of 15 genetic loci associated with risk of major depression in individuals of European descent
inferredcites →https://doi.org/10.1038/nn.2934openalex-snapshot
Sleep and waking modulate spine turnover in the adolescent mouse cortex
inferredcites →https://doi.org/10.1038/nn.4393openalex-snapshot
Multimodal population brain imaging in the UK Biobank prospective epidemiological study
inferredcites →https://doi.org/10.1038/nrn2345openalex-snapshot
Cognitive therapy versus medication for depression: treatment outcomes and neural mechanisms
inferredcites →https://doi.org/10.1038/nrn2793openalex-snapshot
The neuroscience of human intelligence differences
inferredcites →https://doi.org/10.1038/nrn3857openalex-snapshot
Salience processing and insular cortical function and dysfunction
inferredcites →https://doi.org/10.1038/nrn4044openalex-snapshot
The neural bases of emotion regulation
inferredcites →https://doi.org/10.1038/s41467-018-02974-xopenalex-snapshot
No evidence that carotenoid pigments boost either immune or antioxidant defenses in a songbird
inferredcites →https://doi.org/10.1038/s41467-018-03819-3openalex-snapshot
Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways
inferredcites →https://doi.org/10.1038/s41586-018-0571-7openalex-snapshot
Genome-wide association studies of brain imaging phenotypes in UK Biobank
inferredcites →https://doi.org/10.1038/s41588-018-0090-3openalex-snapshot
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
inferredcites →https://doi.org/10.1038/s41588-018-0099-7openalex-snapshot
Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases
inferredcites →https://doi.org/10.1038/s41593-018-0326-7openalex-snapshot
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions
inferredcites →https://doi.org/10.1038/s41598-016-0001-8openalex-snapshot
Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease
inferredcites →https://doi.org/10.1038/s41598-017-05507-6openalex-snapshot
Subcortical volume and white matter integrity abnormalities in major depressive disorder: findings from UK Biobank imaging data
inferredcites →https://doi.org/10.1038/srep24710openalex-snapshot
Events in Early Life are Associated with Female Reproductive Ageing: A UK Biobank Study
inferredcites →https://doi.org/10.1038/srep41926openalex-snapshot
Limb proportions show developmental plasticity in response to embryo movement
inferredcites →https://doi.org/10.1038/srep42140openalex-snapshot
Association of polygenic risk for major psychiatric illness with subcortical volumes and white matter integrity in UK Biobank
inferredcites →https://doi.org/10.1038/tp.2016.246openalex-snapshot
Molecular genetic aetiology of general cognitive function is enriched in evolutionarily conserved regions
inferredcites →https://doi.org/10.1073/pnas.1105108108openalex-snapshot
Extraordinary neoteny of synaptic spines in the human prefrontal cortex
inferredcites →https://doi.org/10.1093/bioinformatics/btu848openalex-snapshot
PRSice: Polygenic Risk Score software
inferredcites →https://doi.org/10.1093/ije/dyh132openalex-snapshot
Mendelian randomization: prospects, potentials, and limitations
inferredcites →https://doi.org/10.1097/ede.0000000000000559openalex-snapshot
Sensitivity Analyses for Robust Causal Inference from Mendelian Randomization Analyses with Multiple Genetic Variants
inferredcites →https://doi.org/10.1097/hrp.0000000000000054openalex-snapshot
Genetic Determinants of Depression
inferredcites →https://doi.org/10.1101/166298openalex-snapshot
Genome-wide genetic data on ~500,000 UK Biobank participants
inferredcites →https://doi.org/10.1101/178806openalex-snapshot
Genome-wide association studies of brain structure and function in the UK Biobank
inferredcites →https://doi.org/10.1111/j.1749-6632.2009.04978.xopenalex-snapshot
Risk Factors for Development of Depression and Psychosis
inferredcites →https://doi.org/10.1111/jcpp.12295openalex-snapshot
Research Review: Polygenic methods and their application to psychiatric traits
inferredcites →https://doi.org/10.1126/science.1202839openalex-snapshot
Sleep and Synaptic Homeostasis: Structural Evidence in Drosophila
inferredcites →https://doi.org/10.1136/jech-2016-207267openalex-snapshot
Psychological distress, neuroticism, and cause-specific mortality: early prospective evidence from UK Biobank
inferredcites →https://doi.org/10.1176/appi.ajp.157.10.1552openalex-snapshot
Genetic Epidemiology of Major Depression: Review and Meta-Analysis
inferredcites →https://doi.org/10.1176/appi.ajp.2011.11020191openalex-snapshot
A Critical Review of the First 10 Years of Candidate Gene-by-Environment Interaction Research in Psychiatry
inferredcites →https://doi.org/10.1192/bjo.2018.12openalex-snapshot
RETRACTED – Mental health in UK Biobank: development, implementation and results from an online questionnaire completed by 157 366 participants
inferredcites →https://doi.org/10.1192/bjp.bp.113.143081openalex-snapshot
Effect of polygenic risk scores on depression in childhood trauma
inferredcites →https://doi.org/10.1371/journal.pmed.1001779openalex-snapshot
UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age
inferredcites →https://doi.org/10.1371/journal.pmed.1001878openalex-snapshot
Changes in Intake of Fruits and Vegetables and Weight Change in United States Men and Women Followed for Up to 24 Years: Analysis from Three Prospective Cohort Studies
inferredcites →https://doi.org/10.1371/journal.pone.0075362openalex-snapshot
Prevalence and Characteristics of Probable Major Depression and Bipolar Disorder within UK Biobank: Cross-Sectional Study of 172,751 Participants
inferredcites →https://doi.org/10.18637/jss.v057.i01openalex-snapshot
lavaan.survey: AnRPackage for Complex Survey Analysis of Structural Equation Models
inferredcites →https://doi.org/10.3102/10769986025001060openalex-snapshot
On the Adaptive Control of the False Discovery Rate in Multiple Testing With Independent Statistics
inferredcites →https://doi.org/10.3758/cabn.10.4.470openalex-snapshot
Neural correlates of rumination in depression
inferredcites →https://doi.org/10.7554/elife.34110openalex-snapshot
A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice
inferredcites →https://doi.org/10.7554/elife.34408openalex-snapshot
The MR-Base platform supports systematic causal inference across the human phenome
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1016/j.bpsc.2024.11.003openalex-snapshot
Multimodal Brain Age Indicators of Internalizing Problems in Early Adolescence: A Longitudinal Investigation
inferred← citeshttps://doi.org/10.1016/j.jare.2026.05.050openalex-snapshot
Predicting risk of mental health deterioration using multimodal data from the UK biobank
inferred← citeshttps://doi.org/10.1038/s41380-021-01260-5openalex-snapshot
Grey and white matter microstructure is associated with polygenic risk for schizophrenia
inferred← citeshttps://doi.org/10.1038/s41380-025-02927-zopenalex-snapshot
Polygenic scores for autism are associated with reduced neurite density in adults and children from the general population
inferred← citeshttps://doi.org/10.1038/s41380-025-03136-4openalex-snapshot
Association between polygenic risk for Major Depression and brain structure in a mega-analysis of 50,975 participants across 11 studies
inferred← citeshttps://doi.org/10.1038/s41398-021-01522-4openalex-snapshot
Phenotypic and genetic associations between anhedonia and brain structure in UK Biobank
inferred← citeshttps://doi.org/10.1038/s41398-022-01782-8openalex-snapshot
Associations between genetic loci, environment factors and mental disorders: a genome-wide survival analysis using the UK Biobank data
inferred← citeshttps://doi.org/10.1038/s41562-024-01903-xopenalex-snapshot
Identifying behaviour-related and physiological risk factors for suicide attempts in the UK Biobank
inferred← citeshttps://doi.org/10.1101/2022.03.29.22273047openalex-snapshot
Cerebrovascular risk factors impact brain phenotypes and cognitive function in healthy population
inferred← citeshttps://doi.org/10.1101/2024.06.24.24309385openalex-snapshot
Exploring the potential risk factors of myopia: A phenome-wide Mendelian randomization association study
inferred← citeshttps://doi.org/10.1136/bmjopen-2023-077799openalex-snapshot
Neuroimaging of neuropsychological disturbances following ischaemic stroke (CONNECT): a prospective cohort study protocol
inferred← citeshttps://doi.org/10.1161/jaha.121.026561openalex-snapshot
Inference of Causal Relationships Between Genetic Risk Factors for Cardiometabolic Phenotypes and Female‐Specific Health Conditions
inferred← citeshttps://doi.org/10.1371/journal.pgen.1011112openalex-snapshot
An augmented Mendelian randomization approach provides causality of brain imaging features on complex traits in a single biobank-scale dataset
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