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Genome-wide association studies of brain structure and function in the UK Biobank

https://doi.org/10.1101/178806
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Analysis ofALDH1A2,CYP26A1,CYP26B1,CRABP1, andCRABP2 in human neural tube defects suggests a possible association with alleles inALDH1A2
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Cortical Surface-Based Analysis
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Accurate, Robust, and Automated Longitudinal and Cross-Sectional Brain Change Analysis
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Exome Sequence Reveals Mutations in CoA Synthase as a Cause of Neurodegeneration with Brain Iron Accumulation
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Interleukin-34 Selectively Enhances the Neuroprotective Effects of Microglia to Attenuate Oligomeric Amyloid-β Neurotoxicity
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Functional roles of transferrin in the brain
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Heritability of Subcortical and Limbic Brain Volume and Shape in Multiplex-Multigenerational Families with Schizophrenia
inferredcites →https://doi.org/10.1016/j.hlpt.2012.07.003openalex-snapshot
UK Biobank: Current status and what it means for epidemiology
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MR susceptibility imaging
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Possible association of the semaphorin 3D gene (SEMA3D) with schizophrenia
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Genetic and environmental influences on the size of specific brain regions in midlife: The VETSA MRI study
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Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort
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Automatic parcellation of human cortical gyri and sulci using standard anatomical nomenclature
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DTI measures in crossing-fibre areas: Increased diffusion anisotropy reveals early white matter alteration in MCI and mild Alzheimer's disease
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NODDI: Practical in vivo neurite orientation dispersion and density imaging of the human brain
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Heritability of subcortical brain measures: A perspective for future genome-wide association studies
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Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank
inferredcites →https://doi.org/10.1016/j.neuron.2012.04.009openalex-snapshot
De Novo Gene Disruptions in Children on the Autistic Spectrum
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Statistical Challenges in “Big Data” Human Neuroimaging
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Voxel-based lesion-symptom mapping of stroke lesions underlying somatosensory deficits
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Disrupted focal white matter integrity in autism spectrum disorder: A voxel-based meta-analysis of diffusion tensor imaging studies
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The multiple-demand (MD) system of the primate brain: mental programs for intelligent behaviour
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The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation
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A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release
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Dopaminergic modulation of impaired cognitive activation in the anterior cingulate cortex in schizophrenia
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A novel Alzheimer disease locus located near the gene encoding tau protein
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Genetic overlap between Alzheimer’s disease and Parkinson’s disease at the MAPT locus
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Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17
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Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
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Intranasal epidermal growth factor treatment rescues neonatal brain injury
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Biological insights from 108 schizophrenia-associated genetic loci
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Common genetic variants influence human subcortical brain structures
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Genetic effects on gene expression across human tissues
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Untangling the brain’s neuroinflammatory and neurodegenerative transcriptional responses
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Novel genetic loci associated with hippocampal volume
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Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis
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Discovery and refinement of loci associated with lipid levels
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Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index
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Partitioning heritability by functional annotation using genome-wide association summary statistics
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An atlas of genetic correlations across human diseases and traits
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A multiple-phenotype imputation method for genetic studies
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Detection and interpretation of shared genetic influences on 42 human traits
inferredcites →https://doi.org/10.1038/ng.859openalex-snapshot
Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy
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The effects of human population structure on large genetic association studies
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A common inversion under selection in Europeans
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Multimodal population brain imaging in the UK Biobank prospective epidemiological study
inferredcites →https://doi.org/10.1038/npjschz.2016.2openalex-snapshot
Increased cortical expression of the zinc transporter SLC39A12 suggests a breakdown in zinc cellular homeostasis as part of the pathophysiology of schizophrenia
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Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
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Variation in MAPT is associated with cerebrospinal fluid tau levels in the presence of amyloid-beta deposition
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The mystery of missing heritability: Genetic interactions create phantom heritability
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inferredcites →https://doi.org/10.1093/hmg/ddw012openalex-snapshot
Genome-wide association and Mendelian randomization study of NT-proBNP in patients with acute coronary syndrome
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White Matter Extracellular Matrix Chondroitin Sulfate/Dermatan Sulfate Proteoglycans in Multiple Sclerosis
inferredcites →https://doi.org/10.1093/schbul/sbs118openalex-snapshot
Brain Volumes in Schizophrenia: A Meta-Analysis in Over 18 000 Subjects
inferredcites →https://doi.org/10.1101/035170openalex-snapshot
A reference panel of 64,976 haplotypes for genotype imputation
inferredcites →https://doi.org/10.1101/166298openalex-snapshot
Genome-wide genetic data on ~500,000 UK Biobank participants
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Fast and robust fixed-point algorithms for independent component analysis
inferredcites →https://doi.org/10.1111/j.1745-6924.2009.01125.xopenalex-snapshot
Puzzlingly High Correlations in fMRI Studies of Emotion, Personality, and Social Cognition
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Impact of family structure and common environment on heritability estimation for neuroimaging genetics studies using Sequential Oligogenic Linkage Analysis Routines
inferredcites →https://doi.org/10.1126/science.1096437openalex-snapshot
Mutations in a Human ROBO Gene Disrupt Hindbrain Axon Pathway Crossing and Morphogenesis
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Learning to identify CNS drug action and efficacy using multistudy fMRI data
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A Singular Value Thresholding Algorithm for Matrix Completion
inferredcites →https://doi.org/10.1176/appi.ajp.2010.09091380openalex-snapshot
Genome-Wide Association Study of Major Recurrent Depression in the U.K. Population
inferredcites →https://doi.org/10.1186/1471-2350-12-123openalex-snapshot
Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits
inferredcites →https://doi.org/10.1186/2040-2392-4-25openalex-snapshot
Comparison of white matter integrity between autism spectrum disorder subjects and typically developing individuals: a meta-analysis of diffusion tensor imaging tractography studies
inferredcites →https://doi.org/10.1371/journal.pmed.1001779openalex-snapshot
UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age
inferredcites →https://doi.org/10.1371/journal.pmed.1002383openalex-snapshot
Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis
inferredcites →https://doi.org/10.1375/136905202762342026openalex-snapshot
Variance Components Models for Gene–Environment Interaction in Twin Analysis
inferredcites →https://doi.org/10.1523/jneurosci.2947-13.2014openalex-snapshot
Astroglial-Derived Periostin Promotes Axonal Regeneration after Spinal Cord Injury
inferredcites →https://doi.org/10.2174/1570159x113119990037openalex-snapshot
Neurodevelopment in Schizophrenia: The Role of the Wnt Pathways
inferredcites →https://doi.org/10.3174/ajnr.a4552openalex-snapshot
Disorders of Microtubule Function in Neurons: Imaging Correlates
inferredcites →https://doi.org/10.3389/fncel.2016.00204openalex-snapshot
A Case for Microtubule Vulnerability in Amyotrophic Lateral Sclerosis: Altered Dynamics During Disease
inferredcites →https://doi.org/10.3389/fnins.2012.00171openalex-snapshot
101 Labeled Brain Images and a Consistent Human Cortical Labeling Protocol
inferredcites →https://doi.org/10.3389/fphar.2014.00019openalex-snapshot
Mitochondrial ferritin in the regulation of brain iron homeostasis and neurodegenerative diseases
inferredcites →https://doi.org/10.3945/jn.110.130351openalex-snapshot
HFE Gene Variants Affect Iron in the Brain1–3
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The heritability of multi-modal connectivity in human brain activity

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1007/s11682-018-9879-zopenalex-snapshot
A systematic review of associations between functional MRI activity and polygenic risk for schizophrenia and bipolar disorder
inferred← citeshttps://doi.org/10.1016/b978-0-12-813838-0.00008-xopenalex-snapshot
Genetics of brain networks and connectivity
inferred← citeshttps://doi.org/10.1016/j.biopsych.2017.11.010openalex-snapshot
Replication in Imaging Genetics: The Case of Threat-Related Amygdala Reactivity
inferred← citeshttps://doi.org/10.1038/s41366-018-0120-3openalex-snapshot
Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE
inferred← citeshttps://doi.org/10.1038/s41398-020-01157-xopenalex-snapshot
Maternal cafeteria diet exposure primes depression-like behavior in the offspring evoking lower brain volume related to changes in synaptic terminals and gliosis
inferred← citeshttps://doi.org/10.1038/s41467-018-05444-6openalex-snapshot
Fast and powerful genome wide association of dense genetic data with high dimensional imaging phenotypes
inferred← citeshttps://doi.org/10.1038/s41467-018-07743-4openalex-snapshot
GWAS identifies 14 loci for device-measured physical activity and sleep duration
inferred← citeshttps://doi.org/10.1038/s41467-018-07863-xopenalex-snapshot
Low-frequency variation in TP53 has large effects on head circumference and intracranial volume
inferred← citeshttps://doi.org/10.1038/s41467-020-16022-0openalex-snapshot
A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank
inferred← citeshttps://doi.org/10.1038/s41588-019-0361-7openalex-snapshot
Biological and clinical insights from genetics of insomnia symptoms
inferred← citeshttps://doi.org/10.1038/s41593-019-0379-2openalex-snapshot
The spatial correspondence and genetic influence of interhemispheric connectivity with white matter microstructure
inferred← citeshttps://doi.org/10.1038/s41598-023-43193-9openalex-snapshot
Consistent effects of the genetics of happiness across the lifespan and ancestries in multiple cohorts
inferred← citeshttps://doi.org/10.1038/s42255-023-00807-wopenalex-snapshot
A non-coding variant linked to metabolic obesity with normal weight affects actin remodelling in subcutaneous adipocytes
inferred← citeshttps://doi.org/10.1101/2022.04.05.487098openalex-snapshot
A Genome-Wide Association Analysis of Happiness: Consistent Genetic Effects Across the Lifespan and Across Genetic Ancestries in Multiple Cohorts
inferred← citeshttps://doi.org/10.1101/2022.08.11.22278677openalex-snapshot
Common Genetic Variation Important in Early Subcortical Brain Development
inferred← citeshttps://doi.org/10.1101/617969openalex-snapshot
A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank
inferred← citeshttps://doi.org/10.1101/808444openalex-snapshot
Identification of putative effector genes across the GWAS Catalog using molecular quantitative trait loci from 68 tissues and cell types
inferred← citeshttps://doi.org/10.1176/appi.ajp.2018.18020149openalex-snapshot
Genetic Markers of ADHD-Related Variations in Intracranial Volume
inferred← citeshttps://doi.org/10.1186/s13073-017-0496-zopenalex-snapshot
Neuroimaging genomics in psychiatry—a translational approach
inferred← citeshttps://doi.org/10.3174/ajnr.a5847openalex-snapshot
Interaction of Developmental Venous Anomalies with Resting-State Functional MRI Measures
inferred← citeshttps://doi.org/10.3233/jad-215053openalex-snapshot
Plasma EFEMP1 Is Associated with Brain Aging and Dementia: The Framingham Heart Study
inferred← citeshttps://doi.org/10.3389/fradi.2021.777030openalex-snapshot
Integrating Transcriptomics, Genomics, and Imaging in Alzheimer's Disease: A Federated Model
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.