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Novel syngeneic animal model of tobacco-associated oral cancer reveals the activity of in situ anti-CTLA-4

https://doi.org/10.1101/672527
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Signatures of mutational processes in human cancer
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Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck
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PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
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Intratumoral immunotherapy: using the tumor as the remedy
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Fast and accurate short read alignment with Burrows–Wheeler transform
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CTLA-4 and PD-1 Pathways
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The Repertoire of Mutational Signatures in Human Cancer
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Mutant p53: one name, many proteins
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VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing
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Mutational signatures associated with tobacco smoking in human cancer
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Decreased Lymphangiogenesis and Lymph Node Metastasis by mTOR Inhibition in Head and Neck Cancer
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Genetic Identification of SEMA3F as an Antilymphangiogenic Metastasis Suppressor Gene in Head and Neck Squamous Carcinoma
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Reversing T-cell Dysfunction and Exhaustion in Cancer
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Targeting Mammalian Target of Rapamycin by Rapamycin Prevents Tumor Progression in an Oral-Specific Chemical Carcinogenesis Model
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Chemical Carcinogenesis Models for Evaluating Molecular-Targeted Prevention and Treatment of Oral Cancer
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Metformin Prevents the Development of Oral Squamous Cell Carcinomas from Carcinogen-Induced Premalignant Lesions
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Fundamental Mechanisms of Immune Checkpoint Blockade Therapy
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The head and neck cancer immune landscape and its immunotherapeutic implications
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Immune related adverse events associated with anti-CTLA-4 antibodies: systematic review and meta-analysis
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Impact of Cigarette Smoking on Cancer Risk in the European Prospective Investigation into Cancer and Nutrition Study
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Immunology and Immunotherapy of Head and Neck Cancer
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Epidemiology of Human Papillomavirus–Positive Head and Neck Squamous Cell Carcinoma
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Antitumor Activity of Pembrolizumab in Biomarker-Unselected Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma: Results From the Phase Ib KEYNOTE-012 Expansion Cohort
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Lollipops in the Clinic: Information Dense Mutation Plots for Precision Medicine
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Emerging drugs to treat squamous cell carcinomas of the head and neck
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American Cancer Society Head and Neck Cancer Survivorship Care Guideline
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Cancer statistics, 2019
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Application of molecular targeted therapies in the treatment of head and neck squamous cell carcinoma (Review)
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Intratumoral Delivery of Immunotherapy—Act Locally, Think Globally
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