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CD44 alternative splicing is a sensor of intragenic DNA methylation in tumors

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/mc.22919openalex-snapshot
The long non‐coding RNA MALAT1 promotes ovarian cancer progression by regulating RBFOX2‐mediated alternative splicing
inferredcites →https://doi.org/10.1002/path.4129openalex-snapshot
The splicing factor SRSF6 is amplified and is an oncoprotein in lung and colon cancers
inferredcites →https://doi.org/10.1002/wrna.1476openalex-snapshot
Alternative‐splicing defects in cancer: Splicing regulators and their downstream targets, guiding the way to novel cancer therapeutics
inferredcites →https://doi.org/10.1016/0092-8674(89)90639-9openalex-snapshot
A human lymphocyte homing receptor, the Hermes antigen, is related to cartilage proteoglycan core and link proteins
inferredcites →https://doi.org/10.1016/j.bbagrm.2015.01.004openalex-snapshot
hnRNP L inhibits CD44 V10 exon splicing through interacting with its upstream intron
inferredcites →https://doi.org/10.1016/j.bbcan.2010.03.003openalex-snapshot
Genome-wide hypomethylation in cancer may be a passive consequence of transformation
inferredcites →https://doi.org/10.1016/j.bbcan.2017.06.006openalex-snapshot
EMT transcription factors in cancer development re-evaluated: Beyond EMT and MET
inferredcites →https://doi.org/10.1016/j.canlet.2017.08.022openalex-snapshot
Osteopontin and their roles in hematological malignancies: Splice variants on the new avenues
inferredcites →https://doi.org/10.1016/j.cell.2013.02.034openalex-snapshot
Dynamic Integration of Splicing within Gene Regulatory Pathways
inferredcites →https://doi.org/10.1016/j.cell.2013.03.011openalex-snapshot
Methylation-Dependent and -Independent Genomic Targeting Principles of the MBD Protein Family
inferredcites →https://doi.org/10.1016/j.celrep.2015.01.038openalex-snapshot
HP1 Is Involved in Regulating the Global Impact of DNA Methylation on Alternative Splicing
inferredcites →https://doi.org/10.1016/j.celrep.2015.07.024openalex-snapshot
Role of DNA Methylation in Modulating Transcription Factor Occupancy
inferredcites →https://doi.org/10.1016/j.celrep.2016.02.063openalex-snapshot
Alternative Splicing of G9a Regulates Neuronal Differentiation
inferredcites →https://doi.org/10.1016/j.molcel.2014.03.044openalex-snapshot
How Slow RNA Polymerase II Elongation Favors Alternative Exon Skipping
inferredcites →https://doi.org/10.1016/j.molcel.2015.09.005openalex-snapshot
SRSF1-Regulated Alternative Splicing in Breast Cancer
inferredcites →https://doi.org/10.1016/j.neo.2016.07.007openalex-snapshot
DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis
inferredcites →https://doi.org/10.1016/s0960-9822(03)00432-9openalex-snapshot
Suv39h-Mediated Histone H3 Lysine 9 Methylation Directs DNA Methylation to Major Satellite Repeats at Pericentric Heterochromatin
inferredcites →https://doi.org/10.1038/416552aopenalex-snapshot
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
inferredcites →https://doi.org/10.1038/cr.2013.110openalex-snapshot
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition
inferredcites →https://doi.org/10.1038/emboj.2011.91openalex-snapshot
KDM5B regulates embryonic stem cell self‐renewal and represses cryptic intragenic transcription
inferredcites →https://doi.org/10.1038/nature01153openalex-snapshot
Signal-dependent regulation of splicing via phosphorylation of Sam68
inferredcites →https://doi.org/10.1038/nature05918openalex-snapshot
Stability and flexibility of epigenetic gene regulation in mammalian development
inferredcites →https://doi.org/10.1038/nature07509openalex-snapshot
Alternative isoform regulation in human tissue transcriptomes
inferredcites →https://doi.org/10.1038/nature08514openalex-snapshot
Human DNA methylomes at base resolution show widespread epigenomic differences
inferredcites →https://doi.org/10.1038/nature10442openalex-snapshot
CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing
inferredcites →https://doi.org/10.1038/nature14176openalex-snapshot
Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation
inferredcites →https://doi.org/10.1038/nature21373openalex-snapshot
Intragenic DNA methylation prevents spurious transcription initiation
inferredcites →https://doi.org/10.1038/ncomms15134openalex-snapshot
Intron retention is regulated by altered MeCP2-mediated splicing factor recruitment
inferredcites →https://doi.org/10.1038/ncomms1892openalex-snapshot
Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell
inferredcites →https://doi.org/10.1038/ncomms5581openalex-snapshot
BCLAF1 and its splicing regulator SRSF10 regulate the tumorigenic potential of colon cancer cells
inferredcites →https://doi.org/10.1038/ng.259openalex-snapshot
Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
inferredcites →https://doi.org/10.1038/ng.322openalex-snapshot
Differential chromatin marking of introns and expressed exons by H3K36me3
inferredcites →https://doi.org/10.1038/ng1158openalex-snapshot
The role of DNA methylation in setting up chromatin structure during development
inferredcites →https://doi.org/10.1038/nsmb.1995openalex-snapshot
Histone H3 lysine 9 trimethylation and HP1γ favor inclusion of alternative exons
inferredcites →https://doi.org/10.1038/nsmb.2123openalex-snapshot
Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36
inferredcites →https://doi.org/10.1038/nsmb.2373openalex-snapshot
Argonaute proteins couple chromatin silencing to alternative splicing
inferredcites →https://doi.org/10.1038/nsmb.2518openalex-snapshot
DNA methylation dynamics in health and disease
inferredcites →https://doi.org/10.1038/nsmb1030openalex-snapshot
The human SWI/SNF subunit Brm is a regulator of alternative splicing
inferredcites →https://doi.org/10.1038/onc.2013.50openalex-snapshot
The RNA-binding protein Rbfox2: an essential regulator of EMT-driven alternative splicing and a mediator of cellular invasion
inferredcites →https://doi.org/10.1038/onc.2017.159openalex-snapshot
DNA methylation variations are required for epithelial-to-mesenchymal transition induced by cancer-associated fibroblasts in prostate cancer cells
inferredcites →https://doi.org/10.1038/s41375-018-0021-4openalex-snapshot
We skip to work: alternative splicing in normal and malignant myelopoiesis
inferredcites →https://doi.org/10.1042/bst20170574openalex-snapshot
Mammalian DNA methyltransferases: new discoveries and open questions
inferredcites →https://doi.org/10.1073/pnas.0507856102openalex-snapshot
Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2
inferredcites →https://doi.org/10.1073/pnas.1109475108openalex-snapshot
Pre-mRNA splicing is a determinant of histone H3K36 methylation
inferredcites →https://doi.org/10.1073/pnas.1708447114openalex-snapshot
Intragenic DNA methylation and BORIS-mediated cancer-specific splicing contribute to the Warburg effect
inferredcites →https://doi.org/10.1074/jbc.m203455200openalex-snapshot
The mCpG-binding Domain of Human MBD3 Does Not Bind to mCpG but Interacts with NuRD/Mi2 Components HDAC1 and MTA2
inferredcites →https://doi.org/10.1074/jbc.m301090200openalex-snapshot
The CD44 Alternative v9 Exon Contains a Splicing Enhancer Responsive to the SR Proteins 9G8, ASF/SF2, and SRp20
inferredcites →https://doi.org/10.1074/jbc.m302283200openalex-snapshot
Methyl-CpG Binding Domain 1 (MBD1) Interacts with the Suv39h1-HP1 Heterochromatic Complex for DNA Methylation-based Transcriptional Repression
inferredcites →https://doi.org/10.1074/jbc.m413654200openalex-snapshot
Transcriptional Repression and Heterochromatin Formation by MBD1 and MCAF/AM Family Proteins
inferredcites →https://doi.org/10.1080/15592294.2015.1078050openalex-snapshot
Integrated methylome and transcriptome analysis reveals novel regulatory elements in pediatric acute lymphoblastic leukemia
inferredcites →https://doi.org/10.1083/jcb.201001073openalex-snapshot
Sam68 regulates EMT through alternative splicing–activated nonsense-mediated mRNA decay of the SF2/ASF proto-oncogene
inferredcites →https://doi.org/10.1093/bioinformatics/btp616openalex-snapshot
edgeR : a Bioconductor package for differential expression analysis of digital gene expression data
inferredcites →https://doi.org/10.1093/bioinformatics/bts356openalex-snapshot
RSeQC: quality control of RNA-seq experiments
inferredcites →https://doi.org/10.1093/bioinformatics/bts635openalex-snapshot
STAR: ultrafast universal RNA-seq aligner
inferredcites →https://doi.org/10.1093/bioinformatics/btt650openalex-snapshot
MEDIPS: genome-wide differential coverage analysis of sequencing data derived from DNA enrichment experiments
inferredcites →https://doi.org/10.1093/bioinformatics/btt656openalex-snapshot
featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
inferredcites →https://doi.org/10.1093/bioinformatics/btw354openalex-snapshot
MultiQC: summarize analysis results for multiple tools and samples in a single report
inferredcites →https://doi.org/10.1093/nar/27.11.2291openalex-snapshot
The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors
inferredcites →https://doi.org/10.1093/nar/gkg332openalex-snapshot
The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase
inferredcites →https://doi.org/10.1093/nar/gkq1267openalex-snapshot
NSrp70 is a novel nuclear speckle-related protein that modulates alternative pre-mRNA splicing in vivo
inferredcites →https://doi.org/10.1093/nar/gkt035openalex-snapshot
Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences
inferredcites →https://doi.org/10.1093/nar/gkv013openalex-snapshot
Alternative splicing regulates the expression of G9A and SUV39H2 methyltransferases, and dramatically changes SUV39H2 functions
inferredcites →https://doi.org/10.1093/nar/gkw257openalex-snapshot
deepTools2: a next generation web server for deep-sequencing data analysis
inferredcites →https://doi.org/10.1093/nar/gkw377openalex-snapshot
Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
inferredcites →https://doi.org/10.1093/nar/gkx900openalex-snapshot
Independence between pre-mRNA splicing and DNA methylation in an isogenic minigene resource
inferredcites →https://doi.org/10.1101/gad.1536807openalex-snapshot
Functional cooperation between HP1 and DNMT1 mediates gene silencing
inferredcites →https://doi.org/10.1101/gad.237206.113openalex-snapshot
An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth
inferredcites →https://doi.org/10.1101/gad.241968.114openalex-snapshot
Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing
inferredcites →https://doi.org/10.1101/gr.125872.111openalex-snapshot
Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer
inferredcites →https://doi.org/10.1101/gr.143503.112openalex-snapshot
DNA-methylation effect on cotranscriptional splicing is dependent on GC architecture of the exon–intron structure
inferredcites →https://doi.org/10.1101/gr.162933.113openalex-snapshot
Endothelial, epithelial, and fibroblast cells exhibit specific splicing programs independently of their tissue of origin
inferredcites →https://doi.org/10.1101/gr.183368.114openalex-snapshot
The role of DNA methylation in directing the functional organization of the cancer epigenome
inferredcites →https://doi.org/10.1126/science.1184208openalex-snapshot
Regulation of Alternative Splicing by Histone Modifications
inferredcites →https://doi.org/10.1128/mcb.01174-12openalex-snapshot
RBFOX2 Is an Important Regulator of Mesenchymal Tissue-Specific Splicing in both Normal and Cancer Tissues
inferredcites →https://doi.org/10.1128/mcb.18.7.3647openalex-snapshot
RB and c-Myc Activate Expression of the E-Cadherin Gene in Epithelial Cells through Interaction with Transcription Factor AP-2
inferredcites →https://doi.org/10.1146/annurev-biochem-052610-091920openalex-snapshot
Programming of DNA Methylation Patterns
inferredcites →https://doi.org/10.1146/annurev-biochem-060614-034242openalex-snapshot
Regulation of Alternative Splicing Through Coupling with Transcription and Chromatin Structure
inferredcites →https://doi.org/10.1152/ajpcell.00009.2009openalex-snapshot
Oxidative stress-induced alternative splicing of transformer 2β (SFRS10) and CD44 pre-mRNAs in gastric epithelial cells
inferredcites →https://doi.org/10.1158/0008-5472.can-04-3294openalex-snapshot
Splicing Factor Tra2-β1 Is Specifically Induced in Breast Cancer and Regulates Alternative Splicing of theCD44Gene
inferredcites →https://doi.org/10.1158/0008-5472.can-06-1888openalex-snapshot
MIRA-Assisted Microarray Analysis, a New Technology for the Determination of DNA Methylation Patterns, Identifies Frequent Methylation of Homeodomain-Containing Genes in Lung Cancer Cells
inferredcites →https://doi.org/10.1172/jci57349openalex-snapshot
G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer
inferredcites →https://doi.org/10.1177/1010428318811525openalex-snapshot
Cell-adhesion molecules and their soluble forms: Promising predictors of “tumor progression” and relapse in leukemia
inferredcites →https://doi.org/10.1186/gb-2008-9-9-r137openalex-snapshot
Model-based Analysis of ChIP-Seq (MACS)
inferredcites →https://doi.org/10.1186/gb-2010-11-7-r70openalex-snapshot
Contrasting chromatin organization of CpG islands and exons in the human genome
inferredcites →https://doi.org/10.1186/gb-2012-13-9-r51openalex-snapshot
The GENCODE pseudogene resource
inferredcites →https://doi.org/10.1186/preaccept-3878619451311053openalex-snapshot
Global loss of DNA methylation uncovers intronic enhancers in genes showing expression changes
inferredcites →https://doi.org/10.1186/s12943-016-0579-2openalex-snapshot
EMT and stemness: flexible processes tuned by alternative splicing in development and cancer progression
inferredcites →https://doi.org/10.1186/s13059-014-0550-8openalex-snapshot
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
inferredcites →https://doi.org/10.1186/s13059-019-1644-0openalex-snapshot
Combined single-cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity
inferredcites →https://doi.org/10.1186/s13148-016-0175-8openalex-snapshot
Genome-wide DNA methylation analysis of pseudohypoparathyroidism patients with GNAS imprinting defects
inferredcites →https://doi.org/10.1261/rna.051151.115openalex-snapshot
Transcriptional control of alternative splicing along time: Ideas change, experiments remain
inferredcites →https://doi.org/10.1261/rna.064865.117openalex-snapshot
The importance of DNA methylation of exons on alternative splicing
inferredcites →https://doi.org/10.1371/journal.pbio.1000506openalex-snapshot
The Honey Bee Epigenomes: Differential Methylation of Brain DNA in Queens and Workers
inferredcites →https://doi.org/10.1371/journal.pgen.1002717openalex-snapshot
Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors and Contributes to the Regulation of Alternative Splicing
inferredcites →https://doi.org/10.1371/journal.pgen.1006318openalex-snapshot
A Broad Set of Chromatin Factors Influences Splicing
inferredcites →https://doi.org/10.1371/journal.pone.0018844openalex-snapshot
Relationship between Gene Body DNA Methylation and Intragenic H3K9me3 and H3K36me3 Chromatin Marks
inferredcites →https://doi.org/10.1371/journal.pone.0099603openalex-snapshot
Genome-Wide Binding of MBD2 Reveals Strong Preference for Highly Methylated Loci
inferredcites →https://doi.org/10.15252/embj.201593235openalex-snapshot
TET‐catalyzed oxidation of intragenic 5‐methylcytosine regulates CTCF‐dependent alternative splicing
inferredcites →https://doi.org/10.18632/oncotarget.6879openalex-snapshot
Dlx-2 and glutaminase upregulate epithelial-mesenchymal transition and glycolytic switch
inferredcites →https://doi.org/10.2217/epi.15.39openalex-snapshot
Methyl-CpG-Binding Domain Proteins: Readers of the Epigenome
inferredcites →https://doi.org/10.3389/fimmu.2015.00154openalex-snapshot
CD44 Acts as a Signaling Platform Controlling Tumor Progression and Metastasis
inferredcites →https://doi.org/10.3892/or.2015.4110openalex-snapshot
CD44 alternative splicing and hnRNP A1 expression are associated with the metastasis of breast cancer
inferredcites →https://doi.org/10.4161/epi.22562openalex-snapshot
Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues
inferredcites →https://doi.org/10.4161/epi.6.11.17978openalex-snapshot
Maintenance of DNA methylation: Dnmt3b joins the dance
inferredcites →https://doi.org/10.4161/rna.6.5.9606openalex-snapshot
The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events
inferredcites →https://doi.org/10.59350/rfxks-m8r39openalex-snapshot
STAR: ultrafast universal RNA-seq aligner
inferredcites →https://doi.org/10.7554/elife.11752openalex-snapshot
A new view of transcriptome complexity and regulation through the lens of local splicing variations
inferredcites →https://doi.org/10.7554/elife.25384openalex-snapshot
MeCP2 regulates Tet1-catalyzed demethylation, CTCF binding, and learning-dependent alternative splicing of the BDNF gene in Turtle
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