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Evidence that APP gene copy number changes reflect recombinant vector contamination

https://doi.org/10.1101/706788
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/j.cell.2016.07.025openalex-snapshot
Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex
inferredcites →https://doi.org/10.1016/j.neuron.2014.12.028openalex-snapshot
Cell Lineage Analysis in Human Brain Using Endogenous Retroelements
inferredcites →https://doi.org/10.1038/ncomms4644openalex-snapshot
Processed pseudogenes acquired somatically during cancer development
inferredcites →https://doi.org/10.1038/nn.4388openalex-snapshot
L1-associated genomic regions are deleted in somatic cells of the healthy human brain
inferredcites →https://doi.org/10.1038/s41467-019-11000-7openalex-snapshot
Brain somatic mutations observed in Alzheimer’s disease associated with aging and dysregulation of tau phosphorylation
inferredcites →https://doi.org/10.1038/s41586-018-0718-6openalex-snapshot
Somatic APP gene recombination in Alzheimer’s disease and normal neurons
inferredcites →https://doi.org/10.1073/pnas.1812702115openalex-snapshot
Submegabase copy number variations arise during cerebral cortical neurogenesis as revealed by single-cell whole-genome sequencing
inferredcites →https://doi.org/10.1093/bioinformatics/btw383openalex-snapshot
Vecuum: identification and filtration of false somatic variants caused by recombinant vector contamination
inferredcites →https://doi.org/10.1093/nar/23.11.2049openalex-snapshot
Template-switching during DNA synthesis byThermus aquaticusDNA polymerase I
inferredcites →https://doi.org/10.1101/179705openalex-snapshot
Pan-cancer analysis of whole genomes reveals driver rearrangements promoted by LINE-1 retrotransposition in human tumours
inferredcites →https://doi.org/10.1101/531210openalex-snapshot
The mutational constraint spectrum quantified from variation in 141,456 humans
inferredcites →https://doi.org/10.1101/730291openalex-snapshot
Reply: Evidence that APP gene copy number changes reflect recombinant vector contamination
inferredcites →https://doi.org/10.1126/science.aab1785openalex-snapshot
Somatic mutation in single human neurons tracks developmental and transcriptional history
inferredcites →https://doi.org/10.1126/science.aal1641openalex-snapshot
Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network
inferredcites →https://doi.org/10.1126/science.aao4426openalex-snapshot
Aging and neurodegeneration are associated with increased mutations in single human neurons
inferredcites →https://doi.org/10.1186/gb-2013-14-3-r22openalex-snapshot
Retrotransposition of gene transcripts leads to structural variation in mammalian genomes
inferredcites →https://doi.org/10.1371/journal.pgen.1008043openalex-snapshot
Somatic LINE-1 retrotransposition in cortical neurons and non-brain tissues of Rett patients and healthy individuals
inferredcites →https://doi.org/10.1371/journal.pone.0169774openalex-snapshot
Examining Sources of Error in PCR by Single-Molecule Sequencing
inferredcites →https://doi.org/10.7554/elife.05116openalex-snapshot
Genomic mosaicism with increased amyloid precursor protein (APP) gene copy number in single neurons from sporadic Alzheimer's disease brains
inferredcites →https://doi.org/10.7554/elife.12966openalex-snapshot
Resolving rates of mutation in the brain using single-neuron genomics

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.nbd.2020.105021openalex-snapshot
Somatic mutations in neurodegeneration: An update
inferred← citeshttps://doi.org/10.1016/j.tig.2020.05.004openalex-snapshot
Transposable Elements: A Common Feature of Neurodevelopmental and Neurodegenerative Disorders
inferred← citeshttps://doi.org/10.1101/730291openalex-snapshot
Reply: Evidence that APP gene copy number changes reflect recombinant vector contamination
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