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Modeling and treating GRIN2A developmental and epileptic encephalopathy in mice
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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GRIN2A mutation and early‐onset epileptic encephalopathy: personalized therapy with memantine
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Dextromethorphan Plus Ultra Low‐Dose Quinidine Reduces Pseudobulbar Affect
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Differential expression of five N‐methyl‐D‐aspartate receptor subunit mRNAs in the cerebellum of developing and adult rats
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Kindling of audiogenic seizures in Wistar rats: An EEG study
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Repetition of audiogenic seizures in genetically epilepsy-prone rats induces cortical epileptiform activity and additional seizure behaviors
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Developmental and regional expression in the rat brain and functional properties of four NMDA receptors
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Excess of De Novo Deleterious Mutations in Genes Associated with Glutamatergic Systems in Nonsyndromic Intellectual Disability
inferredcites →https://doi.org/10.1016/j.brainres.2006.03.049openalex-snapshot
Dissociated cortical networks show spontaneously correlated activity patterns during in vitro development
inferredcites →https://doi.org/10.1016/j.cophys.2017.12.013openalex-snapshot
De novo mutations and rare variants occurring in NMDA receptors
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An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior
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Effective parameters for stimulation of dissociated cultures using multi-electrode arrays
inferredcites →https://doi.org/10.1016/j.jphs.2016.10.002openalex-snapshot
Human GRIN2B variants in neurodevelopmental disorders
inferredcites →https://doi.org/10.1016/j.nbd.2016.06.014openalex-snapshot
Dynamin 1 isoform roles in a mouse model of severe childhood epileptic encephalopathy
inferredcites →https://doi.org/10.1016/j.neulet.2003.12.062openalex-snapshot
Longterm stability and developmental changes in spontaneous network burst firing patterns in dissociated rat cerebral cortex cell cultures on multielectrode arrays
inferredcites →https://doi.org/10.1016/j.neuro.2010.04.001openalex-snapshot
Microelectrode arrays: A physiologically based neurotoxicity testing platform for the 21st century
inferredcites →https://doi.org/10.1016/j.neuron.2014.01.035openalex-snapshot
Distinct Functional and Pharmacological Properties of Triheteromeric GluN1/GluN2A/GluN2B NMDA Receptors
inferredcites →https://doi.org/10.1016/j.pharmthera.2016.01.016openalex-snapshot
Dextromethorphan: An update on its utility for neurological and neuropsychiatric disorders
inferredcites →https://doi.org/10.1016/j.yebeh.2012.09.007openalex-snapshot
Unraveling the genetics of common epilepsies: Approaches, platforms, and caveats
inferredcites →https://doi.org/10.1016/s0024-3205(02)02505-5openalex-snapshot
New morphinan derivatives with negligible psychotropic effects attenuate convulsions induced by maximal electroshock in mice
inferredcites →https://doi.org/10.1016/s0165-0270(98)00140-xopenalex-snapshot
Software-based correction of single compartment series resistance errors
inferredcites →https://doi.org/10.1016/s0920-1211(00)00107-8openalex-snapshot
Audiogenic kindling in the Wistar rat: a potential model for recruitment of limbic structures
inferredcites →https://doi.org/10.1016/s0920-1211(01)00302-3openalex-snapshot
Pharmacological characterization of the 6 Hz psychomotor seizure model of partial epilepsy
inferredcites →https://doi.org/10.1038/346565a0openalex-snapshot
Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents
inferredcites →https://doi.org/10.1038/ejhg.2016.163openalex-snapshot
Novel homozygous missense variant of GRIN1 in two sibs with intellectual disability and autistic features without epilepsy
inferredcites →https://doi.org/10.1038/ncomms8168openalex-snapshot
Trans-synaptic zinc mobilization improves social interaction in two mouse models of autism through NMDAR activation
inferredcites →https://doi.org/10.1038/ng.2726openalex-snapshot
GRIN2A mutations in acquired epileptic aphasia and related childhood focal epilepsies and encephalopathies with speech and language dysfunction
inferredcites →https://doi.org/10.1038/ng.2727openalex-snapshot
GRIN2A mutations cause epilepsy-aphasia spectrum disorders
inferredcites →https://doi.org/10.1038/ng.677openalex-snapshot
Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes
inferredcites →https://doi.org/10.1038/nrn3504openalex-snapshot
NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease
inferredcites →https://doi.org/10.1056/nejmoa1206524openalex-snapshot
Diagnostic Exome Sequencing in Persons with Severe Intellectual Disability
inferredcites →https://doi.org/10.1074/jbc.m414215200openalex-snapshot
Conserved Structural and Functional Control of N-Methyl-d-aspartate Receptor Gating by Transmembrane Domain M3
inferredcites →https://doi.org/10.1088/1741-2560/1/1/006openalex-snapshot
A versatile all-channel stimulator for electrode arrays, with real-time control
inferredcites →https://doi.org/10.1093/hmg/ddp081openalex-snapshot
Heterozygous mutations of the voltage-gated sodium channel SCN8A are associated with spike-wave discharges and absence epilepsy in mice
inferredcites →https://doi.org/10.1109/tsmc.1979.4310076openalex-snapshot
A Threshold Selection Method from Gray-Level Histograms
inferredcites →https://doi.org/10.1111/dmcn.13169openalex-snapshot
N‐methyl‐ d ‐aspartate ( NMDA ) receptor antibodies encephalitis mimicking an autistic regression
inferredcites →https://doi.org/10.1111/epi.13764openalex-snapshot
Development and pharmacologic characterization of the rat 6 Hz model of partial seizures
inferredcites →https://doi.org/10.1111/j.1469-7793.1998.001bz.xopenalex-snapshot
Single‐channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors
inferredcites →https://doi.org/10.1111/j.1476-5381.2009.00304.xopenalex-snapshot
Allosteric modulators of NR2B‐containing NMDA receptors: molecular mechanisms and therapeutic potential
inferredcites →https://doi.org/10.1111/j.1601-183x.2011.00717.xopenalex-snapshot
Etiology of a genetically complex seizure disorder in Celf4 mutant mice
inferredcites →https://doi.org/10.1113/jphysiol.2004.080028openalex-snapshot
Subunit‐specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles
inferredcites →https://doi.org/10.1113/jphysiol.2008.158634openalex-snapshot
Activation of recombinant NR1/NR2C NMDA receptors
inferredcites →https://doi.org/10.1124/mol.115.097998openalex-snapshot
Ionotropic GABA and Glutamate Receptor Mutations and Human Neurologic Diseases
inferredcites →https://doi.org/10.1124/mol.116.106781openalex-snapshot
Functional Evaluation of a De Novo GRIN2A Mutation Identified in a Patient with Profound Global Developmental Delay and Refractory Epilepsy
inferredcites →https://doi.org/10.1124/pr.109.002451openalex-snapshot
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
inferredcites →https://doi.org/10.1128/mcb.7.8.2745openalex-snapshot
High-Efficiency Transformation of Mammalian Cells by Plasmid DNA
inferredcites →https://doi.org/10.1152/jn.00093.2016openalex-snapshot
A comparison of computational methods for detecting bursts in neuronal spike trains and their application to human stem cell-derived neuronal networks
inferredcites →https://doi.org/10.1159/000448530openalex-snapshot
Understanding Genotypes and Phenotypes in Epileptic Encephalopathies
inferredcites →https://doi.org/10.1186/1471-2202-7-11openalex-snapshot
An extremely rich repertoire of bursting patterns during the development of cortical cultures
inferredcites →https://doi.org/10.1371/journal.pcbi.1004559openalex-snapshot
Gene Expression Switching of Receptor Subunits in Human Brain Development
inferredcites →https://doi.org/10.1371/journal.pcbi.1006506openalex-snapshot
meaRtools: An R package for the analysis of neuronal networks recorded on microelectrode arrays
inferredcites →https://doi.org/10.1371/journal.pgen.1005347openalex-snapshot
Independent Neuronal Origin of Seizures and Behavioral Comorbidities in an Animal Model of a Severe Childhood Genetic Epileptic Encephalopathy
inferredcites →https://doi.org/10.1371/journal.pgen.1006536openalex-snapshot
Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology
inferredcites →https://doi.org/10.1371/journal.pone.0141221openalex-snapshot
Repeated 6-Hz Corneal Stimulation Progressively Increases FosB/ΔFosB Levels in the Lateral Amygdala and Induces Seizure Generalization to the Hippocampus
inferredcites →https://doi.org/10.1523/jneurosci.1365-09.2009openalex-snapshot
Control of NMDA Receptor Function by the NR2 Subunit Amino-Terminal Domain
inferredcites →https://doi.org/10.1523/jneurosci.21-22-08782.2001openalex-snapshot
Learning in Networks of Cortical Neurons
inferredcites →https://doi.org/10.1523/jneurosci.22-06-02044.2002openalex-snapshot
The NMDA Receptor M3 Segment Is a Conserved Transduction Element Coupling Ligand Binding to Channel Opening
inferredcites →https://doi.org/10.1523/jneurosci.6107-11.2012openalex-snapshot
Reduced Excitatory Neurotransmission and Mild Autism-Relevant Phenotypes in Adolescent Shank3 Null Mutant Mice
inferredcites →https://doi.org/10.1529/biophysj.107.112730openalex-snapshot
Low-Frequency Stimulation Induces Stable Transitions in Stereotypical Activity in Cortical Networks
inferredcites →https://doi.org/10.2174/156802606776894456openalex-snapshot
NR2B Selective NMDA Antagonists: The Evolution of the Ifenprodil-Type Pharmacophore
inferredcites →https://doi.org/10.31887/dcns.2017.19.1/mleboyeropenalex-snapshot
Clinical and autoimmune features of a patient with autism spectrum disorder seropositive for anti—NMDA-receptor autoantibody
inferredcites →https://doi.org/10.3389/fncel.2016.00281openalex-snapshot
Progressive Seizure Aggravation in the Repeated 6-Hz Corneal Stimulation Model Is Accompanied by Marked Increase in Hippocampal p-ERK1/2 Immunoreactivity in Neurons
inferredcites →https://doi.org/10.4062/biomolther.2018.230openalex-snapshot
Effects of Intraperitoneal N-methyl-D-aspartate (NMDA) Administration on Nociceptive/Repetitive Behaviors in Juvenile Mice
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.33549/physiolres.935346openalex-snapshot
Disease-Associated Variants in GRIN1, GRIN2A and GRIN2B genes: Insights into NMDA Receptor Structure, Function, and Pathophysiology
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