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Sirt3 mediated by lentiviral vector in the periaqueductal gray suppresses morphine withdrawal in rats: A preliminary study

https://doi.org/10.1101/743062
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Physical dependence produced by central morphine infusions: An anatomical mapping study
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Columnar organization in the midbrain periaqueductal gray: modules for emotional expression?
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SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress
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Spinal CPEB-mtROS-CBP signaling pathway contributes to perineural HIV gp120 with ddC-related neuropathic pain in rats
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Oxidative stress in heroin administered mice and natural antioxidants protection
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Active Regulator of SIRT1 Cooperates with SIRT1 and Facilitates Suppression of p53 Activity
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Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress
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Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome
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SENP1-Sirt3 Signaling Controls Mitochondrial Protein Acetylation and Metabolism
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The effects of cocaine: A shifting target over the course of addiction
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SIRT3 regulates progression and development of diseases of aging
inferredcites →https://doi.org/10.1016/s0006-8993(01)02962-6openalex-snapshot
Efferent projections of ProTRH neurons in the ventrolateral periaqueductal gray
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Role of different brain structures in the expression of the physical morphine withdrawal syndrome.
inferredcites →https://doi.org/10.1016/s0022-3565(25)31261-9openalex-snapshot
Development and maintenance of morphine tolerance and dependence in the rat by scheduled access to morphine drinking solutions.
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An Enzymatic Activity in the Yeast Sir2 Protein that Is Essential for Gene Silencing
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Short-term infusion of the μ-opioid agonist remifentanil in humans causes hyperalgesia during withdrawal
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Cellular neuroadaptations to chronic opioids: tolerance, withdrawal and addiction
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Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS
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IL-4 mediated by HSV vector suppresses morphine withdrawal response and decreases TNFα, NR2B, and pC/EBPβ in the periaqueductal gray in rats
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MnSOD mediated by HSV vectors in the periaqueductal gray suppresses morphine withdrawal in rats
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Dopamine receptor D1 and postsynaptic density gene variants associate with opiate abuse and striatal expression levels
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Sirtuin activators mimic caloric restriction and delay ageing in metazoans
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Recent progress in the biology and physiology of sirtuins
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SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
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A thalamic input to the nucleus accumbens mediates opiate dependence
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The Role of TNFα in the Periaqueductal Gray During Naloxone-Precipitated Morphine Withdrawal in Rats
inferredcites →https://doi.org/10.1038/npp.2017.69openalex-snapshot
Sex Differences in Regional Brain Glucose Metabolism Following Opioid Withdrawal and Replacement
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Physical interaction of estrogen receptor with MnSOD: implication in mitochondrial O2.− upregulation and mTORC2 potentiation in estrogen-responsive breast cancer cells
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Spinal administration of lipoxygenase inhibitors suppresses behavioural and neurochemical manifestations of naloxone‐precipitated opioid withdrawal
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Central Opioid Receptors Differentially Regulate the Nalmefene-Induced Suppression of Ethanol- and Saccharin-Reinforced Behaviors in Alcohol-Preferring (P) Rats
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Δ9‐tetrahydrocannabinol releases and facilitates the effects of endogenous enkephalins: reduction in morphine withdrawal syndrome without change in rewarding effect
inferredcites →https://doi.org/10.1073/pnas.0710902105openalex-snapshot
Opioid neuropeptide genotypes in relation to heroin abuse: Dopamine tone contributes to reversed mesolimbic proenkephalin expression
inferredcites →https://doi.org/10.1073/pnas.0803790105openalex-snapshot
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Pharmacogenetic analysis of opioid dependence treatment dose and dropout rate
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Safety concerns with long-term opioid use
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Redox Signaling in Cancer Biology
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Manganese Superoxide Dismutase Acetylation and Dysregulation, Due to Loss of SIRT3 Activity, Promote a Luminal B-Like Breast Carcinogenic-Permissive Phenotype
inferredcites →https://doi.org/10.1093/abbs/gmv013openalex-snapshot
Sirt3–MnSOD axis represses nicotine-induced mitochondrial oxidative stress and mtDNA damage in osteoblasts
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Aids for Easy Venous Cannulation
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The thalamus in drug addiction: from rodents to humans
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The effects of ibudilast, a glial activation inhibitor, on opioid withdrawal symptoms in opioid-dependent volunteers
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β‐Arrestin‐2 knockout prevents development of cellular μ‐opioid receptor tolerance but does not affect opioid‐withdrawal‐related adaptations in single PAG neurons
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Insight Into the Relationship Between Impulsivity and Substance Abuse From Studies Using Animal Models
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Heroin‐Administered Mice Involved in Oxidative Stress and Exogenous Antioxidant‐Alleviated Withdrawal Syndrome
inferredcites →https://doi.org/10.1128/mcb.01636-07openalex-snapshot
Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation
inferredcites →https://doi.org/10.1172/jci39162openalex-snapshot
Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice
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Sirtuin 3–dependent mitochondrial dynamic improvements protect against acute kidney injury
inferredcites →https://doi.org/10.1186/gb-2004-5-5-224openalex-snapshot
Sirtuins: Sir2-related NAD-dependent protein deacetylases.
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Antagonists of the Neurokinin‐1 or Dopamine D1 Receptors Confer Protection from Methamphetamine on Dopamine Terminals of the Mouse Striatum
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Regulation of Gene Expression by Chronic Morphine and Morphine Withdrawal in the Locus Ceruleus and Ventral Tegmental Area
inferredcites →https://doi.org/10.1523/jneurosci.0176-07.2007openalex-snapshot
Glial–Cytokine–Neuronal Interactions Underlying the Mechanisms of Persistent Pain
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Morphine Epigenomically Regulates Behavior through Alterations in Histone H3 Lysine 9 Dimethylation in the Nucleus Accumbens
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Opposite Modulation of Opiate Withdrawal Behaviors on Microinfusion of a Protein Kinase A Inhibitor Versus Activator into the Locus Coeruleus or Periaqueductal Gray
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Mitochondrial Reactive Oxygen Species Are Activated by mGluR5 through IP 3 and Activate ERK and PKA to Increase Excitability of Amygdala Neurons and Pain Behavior
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Drug and Opioid-Involved Overdose Deaths — United States, 2013–2017
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SIRT3: Oncogene and Tumor Suppressor in Cancer
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Sirt3, Mitochondrial ROS, Ageing, and Carcinogenesis
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