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Claudin-12 deficiency causes nerve barrier breakdown, mechanical hypersensitivity and painfulness in polyneuropathy
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/ana.24086openalex-snapshot
Abnormal junctions and permeability of myelin in PMP22‐deficient nerves
inferredcites →https://doi.org/10.1002/jcp.20823openalex-snapshot
Exogenous expression of claudin‐5 induces barrier properties in cultured rat brain capillary endothelial cells
inferredcites →https://doi.org/10.1002/jcp.21508openalex-snapshot
Peripheral Nerve pericytes originating from the blood–nerve barrier expresses tight junctional molecules and transporters as barrier‐forming cells
inferredcites →https://doi.org/10.1002/mus.24930openalex-snapshot
Endoneurial edema in sural nerve may indicate recent onset inflammatory neuropathy
inferredcites →https://doi.org/10.1007/s00018-011-0680-zopenalex-snapshot
Elucidating the principles of the molecular organization of heteropolymeric tight junction strands
inferredcites →https://doi.org/10.1007/s00018-019-03030-7openalex-snapshot
Tight junction proteins at the blood–brain barrier: far more than claudin-5
inferredcites →https://doi.org/10.1007/s00360-009-0440-7openalex-snapshot
Segmental expression of claudin proteins correlates with tight junction barrier properties in rat intestine
inferredcites →https://doi.org/10.1007/s00424-016-1920-8openalex-snapshot
Barrier function in the peripheral and central nervous system—a review
inferredcites →https://doi.org/10.1007/s12264-017-0136-zopenalex-snapshot
Spinal Circuits Transmitting Mechanical Pain and Itch
inferredcites →https://doi.org/10.1016/j.bbadis.2019.01.008openalex-snapshot
Tissue plasminogen activator and neuropathy open the blood-nerve barrier with upregulation of microRNA-155-5p in male rats
inferredcites →https://doi.org/10.1016/j.bbrc.2015.02.108openalex-snapshot
Interleukin-18 enhances breast cancer cell migration via down-regulation of claudin-12 and induction of the p38 MAPK pathway
inferredcites →https://doi.org/10.1016/j.biomaterials.2015.03.007openalex-snapshot
Mode of action of claudin peptidomimetics in the transient opening of cellular tight junction barriers
inferredcites →https://doi.org/10.1016/j.biomaterials.2015.11.053openalex-snapshot
Analgesic drug delivery via recombinant tissue plasminogen activator and microRNA-183-triggered opening of the blood-nerve barrier
inferredcites →https://doi.org/10.1016/j.jconrel.2014.04.029openalex-snapshot
Safety, efficacy, and molecular mechanism of claudin-1-specific peptides to enhance blood–nerve–barrier permeability
inferredcites →https://doi.org/10.1016/j.jinf.2016.08.006openalex-snapshot
The role of primary infection of Schwann cells in the aetiology of infective inflammatory neuropathies
inferredcites →https://doi.org/10.1016/j.neuron.2018.01.033openalex-snapshot
Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability
inferredcites →https://doi.org/10.1016/j.npep.2011.07.011openalex-snapshot
TRPV1, TRPA1, and CB1 in the isolated vagus nerve – Axonal chemosensitivity and control of neuropeptide release
inferredcites →https://doi.org/10.1016/j.pain.2014.01.026openalex-snapshot
Blood-nerve barrier dysfunction contributes to the generation of neuropathic pain and allows targeting of injured nerves for pain relief
inferredcites →https://doi.org/10.1016/s0092-8674(00)81553-6openalex-snapshot
CNS Myelin and Sertoli Cell Tight Junction Strands Are Absent in Osp/Claudin-11 Null Mice
inferredcites →https://doi.org/10.1016/s1474-4422(07)70329-0openalex-snapshot
Intravenous immune globulin (10% caprylate-chromatography purified) for the treatment of chronic inflammatory demyelinating polyradiculoneuropathy (ICE study): a randomised placebo-controlled trial
inferredcites →https://doi.org/10.1016/s1474-4422(17)30378-2openalex-snapshot
Subcutaneous immunoglobulin for maintenance treatment in chronic inflammatory demyelinating polyneuropathy (PATH): a randomised, double-blind, placebo-controlled, phase 3 trial
inferredcites →https://doi.org/10.1038/cddis.2014.446openalex-snapshot
A Smoothened receptor agonist is neuroprotective and promotes regeneration after ischemic brain injury
inferredcites →https://doi.org/10.1038/labinvest.2012.6openalex-snapshot
Estradiol triggers sonic-hedgehog-induced angiogenesis during peripheral nerve regeneration by downregulating hedgehog-interacting protein
inferredcites →https://doi.org/10.1038/ncomms6331openalex-snapshot
Presynaptic GABAergic inhibition regulated by BDNF contributes to neuropathic pain induction
inferredcites →https://doi.org/10.1038/nrm.2016.80openalex-snapshot
Tight junctions: from simple barriers to multifunctional molecular gates
inferredcites →https://doi.org/10.1038/s41572-018-0027-2openalex-snapshot
Immune-mediated neuropathies
inferredcites →https://doi.org/10.1038/s41591-019-0393-7openalex-snapshot
Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis
inferredcites →https://doi.org/10.1038/s41598-017-10241-0openalex-snapshot
Sonic Hedgehog mimetic prevents leukocyte infiltration into the CNS during acute HIV infection
inferredcites →https://doi.org/10.1038/s41598-017-16250-3openalex-snapshot
Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis
inferredcites →https://doi.org/10.1038/s41598-018-22047-9openalex-snapshot
Absence of Claudin 11 in CNS Myelin Perturbs Behavior and Neurotransmitter Levels in Mice
inferredcites →https://doi.org/10.1038/s41598-018-36731-3openalex-snapshot
Claudin-3-deficient C57BL/6J mice display intact brain barriers
inferredcites →https://doi.org/10.1038/sj.bjc.6605517openalex-snapshot
Oestrogen receptor-α contributes to the regulation of the hedgehog signalling pathway in ERα-positive gastric cancer
inferredcites →https://doi.org/10.1038/sj.onc.1205975openalex-snapshot
Novel genes regulated by Sonic Hedgehog in pluripotent mesenchymal cells
inferredcites →https://doi.org/10.1042/bj20150148openalex-snapshot
Probing thecis-arrangement of prototype tight junction proteins claudin-1 and claudin-3
inferredcites →https://doi.org/10.1073/pnas.1120800109openalex-snapshot
Transient opening of the perineurial barrier for analgesic drug delivery
inferredcites →https://doi.org/10.1073/pnas.1614826113openalex-snapshot
Unexpected central role of the androgen receptor in the spontaneous regeneration of myelin
inferredcites →https://doi.org/10.1080/21688370.2016.1154641openalex-snapshot
Junctional proteins of the blood-brain barrier: New insights into function and dysfunction
inferredcites →https://doi.org/10.1080/21688370.2018.1502531openalex-snapshot
Roles of membrane lipids in the organization of epithelial cells: Old and new problems
inferredcites →https://doi.org/10.1080/21688370.2018.1540904openalex-snapshot
Vitamin D Receptor Deletion Leads to the Destruction of Tight and Adherens Junctions in Lungs
inferredcites →https://doi.org/10.1083/jcb.200501154openalex-snapshot
Tight junctions in Schwann cells of peripheral myelinated axons
inferredcites →https://doi.org/10.1089/ars.2010.3542openalex-snapshot
Occludin Protein Family: Oxidative Stress and Reducing Conditions
inferredcites →https://doi.org/10.1089/ars.2013.5288openalex-snapshot
Highly Conserved Cysteines Are Involved in the Oligomerization of Occludin—Redox Dependency of the Second Extracellular Loop
inferredcites →https://doi.org/10.1089/ars.2013.5706openalex-snapshot
Redox-Sensitive Structure and Function of the First Extracellular Loop of the Cell–Cell Contact Protein Claudin-1: Lessons from Molecular Structure to Animals
inferredcites →https://doi.org/10.1091/mbc.e07-09-0973openalex-snapshot
Tight Junction Proteins Claudin-2 and -12 Are Critical for Vitamin D-dependent Ca 2+ Absorption between Enterocytes
inferredcites →https://doi.org/10.1093/brain/awp113openalex-snapshot
PMP22 expression in dermal nerve myelin from patients with CMT1A
inferredcites →https://doi.org/10.1093/brain/awv092openalex-snapshot
Netrin 1 regulates blood–brain barrier function and neuroinflammation
inferredcites →https://doi.org/10.1093/brain/aww189openalex-snapshot
Auto-antibodies to contactin-associated protein 1 (Caspr) in two patients with painful inflammatory neuropathy
inferredcites →https://doi.org/10.1096/fj.07-8319comopenalex-snapshot
Formation of tight junction: determinants of homophilic interaction between classic claudins
inferredcites →https://doi.org/10.1096/fj.11-196220openalex-snapshot
Schwann cell‐specific JAM‐C‐deficient mice reveal novel expression and functions for JAM‐C in peripheral nerves
inferredcites →https://doi.org/10.1097/j.pain.0000000000000444openalex-snapshot
Early alterations of Hedgehog signaling pathway in vascular endothelial cells after peripheral nerve injury elicit blood-nerve barrier disruption, nerve inflammation, and neuropathic pain development
inferredcites →https://doi.org/10.1111/j.1748-1716.2010.02148.xopenalex-snapshot
Claudins of intestine and nephron – a correlation of molecular tight junction structure and barrier function
inferredcites →https://doi.org/10.1111/nyas.13359openalex-snapshot
Claudin peptidomimetics modulate tissue barriers for enhanced drug delivery
inferredcites →https://doi.org/10.1111/nyas.13436openalex-snapshot
Blood–spinal cord barrier breakdown and pericyte deficiency in peripheral neuropathy
inferredcites →https://doi.org/10.1113/jphysiol.2010.197764openalex-snapshot
Inflammatory mediators weaken the amniotic membrane barrier through disruption of tight junctions
inferredcites →https://doi.org/10.1126/science.1206936openalex-snapshot
The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence
inferredcites →https://doi.org/10.1126/science.aaf8924openalex-snapshot
Pain regulation by non-neuronal cells and inflammation
inferredcites →https://doi.org/10.1136/jnnp.2003.025692openalex-snapshot
Chronic inflammatory demyelinating polyneuropathy: decreased claudin-5 and relocated ZO-1
inferredcites →https://doi.org/10.1136/jnnp.72.5.596openalex-snapshot
Clinimetric evaluation of a new overall disability scale in immune mediated polyneuropathies
inferredcites →https://doi.org/10.1152/ajpcell.00434.2011openalex-snapshot
Claudin-4 forms a paracellular barrier, revealing the interdependence of claudin expression in the loose epithelial cell culture model opossum kidney cells
inferredcites →https://doi.org/10.1159/000268116openalex-snapshot
Inflammation and Hypersensitivity in the Context of the Sensory Functions of Axonal Membranes: What Are the Molecular Mechanisms?
inferredcites →https://doi.org/10.1177/0022034516679395openalex-snapshot
Hedgehog Pathway–Mediated Vascular Alterations Following Trigeminal Nerve Injury
inferredcites →https://doi.org/10.1177/1744806917727625openalex-snapshot
Could an endoneurial endothelial crosstalk between Wnt/β-catenin and Sonic Hedgehog pathways underlie the early disruption of the infraorbital blood–nerve barrier following chronic constriction injury?
inferredcites →https://doi.org/10.1186/s12974-015-0469-3openalex-snapshot
Modeling leukocyte trafficking at the human blood-nerve barrier in vitro and in vivo geared towards targeted molecular therapies for peripheral neuroinflammation
inferredcites →https://doi.org/10.1186/s12974-016-0738-9openalex-snapshot
Neurogenic inflammation after traumatic brain injury and its potentiation of classical inflammation
inferredcites →https://doi.org/10.1186/s12987-019-0150-9openalex-snapshot
Claudin-12 is not required for blood–brain barrier tight junction function
inferredcites →https://doi.org/10.1242/jcs.113.13.2363openalex-snapshot
Human junction adhesion molecule regulates tight junction resealing in epithelia
inferredcites →https://doi.org/10.1242/jcs.114306openalex-snapshot
In tight junctions, claudins regulate the interactions between occludin, tricellulin and marvelD3, which, inversely, modulate claudin oligomerization
inferredcites →https://doi.org/10.1371/journal.pone.0018139openalex-snapshot
The Effects of Th17 Cytokines on the Inflammatory Mediator Production and Barrier Function of ARPE-19 Cells
inferredcites →https://doi.org/10.1371/journal.pone.0055972openalex-snapshot
Inhibition of Glycogen Synthase Kinase 3β Promotes Tight Junction Stability in Brain Endothelial Cells by Half-Life Extension of Occludin and Claudin-5
inferredcites →https://doi.org/10.1371/journal.pone.0104205openalex-snapshot
Severity and Patterns of Blood-Nerve Barrier Breakdown in Patients with Chronic Inflammatory Demyelinating Polyradiculoneuropathy: Correlations with Clinical Subtypes
inferredcites →https://doi.org/10.1371/journal.pone.0182106openalex-snapshot
Cross-over endocytosis of claudins is mediated by interactions via their extracellular loops
inferredcites →https://doi.org/10.1385/1-59259-419-0:51openalex-snapshot
Freeze-Fracture Studies of Cerebral Endothelial Tight Junctions
inferredcites →https://doi.org/10.1523/jneurosci.3030-17.2018openalex-snapshot
Macrophage Depletion Ameliorates Peripheral Neuropathy in Aging Mice
inferredcites →https://doi.org/10.1523/jneurosci.3342-12.2013openalex-snapshot
Schwann Cell LRP1 Regulates Remak Bundle Ultrastructure and Axonal Interactions to Prevent Neuropathic Pain
inferredcites →https://doi.org/10.1523/jneurosci.4264-09.2010openalex-snapshot
Conduction Block in PMP22 Deficiency
inferredcites →https://doi.org/10.3389/fnins.2018.00936openalex-snapshot
Quantitative and Microstructural Changes of the Blood-Nerve Barrier in Peripheral Neuropathy
inferredcites →https://doi.org/10.3390/ijms18091965openalex-snapshot
Blood-Brain Barrier Dysfunction and the Pathogenesis of Alzheimer’s Disease
inferredcites →https://doi.org/10.4103/1673-5374.213537openalex-snapshot
Transcriptional inhibition in Schwann cell development and nerve regeneration
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1158/0008-5472.c.6514082.v1openalex-snapshot
Data from Claudin-12 Deficiency Inhibits Tumor Growth by Impairing Transendothelial Migration of Myeloid-Derived Suppressor Cells
inferred← citeshttps://doi.org/10.1158/0008-5472.can-21-3896openalex-snapshot
Claudin-12 Deficiency Inhibits Tumor Growth by Impairing Transendothelial Migration of Myeloid-Derived Suppressor Cells
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