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Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

https://doi.org/10.1101/782748
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/j.cell.2014.10.039openalex-snapshot
Geroscience: Linking Aging to Chronic Disease
inferredcites →https://doi.org/10.1016/j.stem.2018.01.011openalex-snapshot
Clonal Hematopoiesis and Evolution to Hematopoietic Malignancies
inferredcites →https://doi.org/10.1038/nbt.2514openalex-snapshot
Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
inferredcites →https://doi.org/10.1038/ng.2566openalex-snapshot
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
inferredcites →https://doi.org/10.1038/ng.3545openalex-snapshot
Mosaic loss of chromosome Y is associated with common variation near TCL1A
inferredcites →https://doi.org/10.1038/ng.3646openalex-snapshot
Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution
inferredcites →https://doi.org/10.1038/nm.3733openalex-snapshot
Age-related mutations associated with clonal hematopoietic expansion and malignancies
inferredcites →https://doi.org/10.1038/s41467-018-06159-4openalex-snapshot
Functional equivalence of genome sequencing analysis pipelines enables harmonized variant calling across human genetics projects
inferredcites →https://doi.org/10.1038/s41586-018-0321-xopenalex-snapshot
Insights into clonal haematopoiesis from 8,342 mosaic chromosomal alterations
inferredcites →https://doi.org/10.1038/s41586-021-03205-yopenalex-snapshot
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program
inferredcites →https://doi.org/10.1038/s41588-018-0184-yopenalex-snapshot
Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies
inferredcites →https://doi.org/10.1038/s41598-019-45839-zopenalex-snapshot
The ENCODE Blacklist: Identification of Problematic Regions of the Genome
inferredcites →https://doi.org/10.1056/nejmoa1408617openalex-snapshot
Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes
inferredcites →https://doi.org/10.1056/nejmoa1409405openalex-snapshot
Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
inferredcites →https://doi.org/10.1056/nejmoa1701719openalex-snapshot
Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease
inferredcites →https://doi.org/10.1086/426403openalex-snapshot
CHEK2 Is a Multiorgan Cancer Susceptibility Gene
inferredcites →https://doi.org/10.1093/bioinformatics/bts124openalex-snapshot
CpGassoc: an R function for analysis of DNA methylation microarray data
inferredcites →https://doi.org/10.1093/bioinformatics/btw691openalex-snapshot
Preprocessing, normalization and integration of the Illumina HumanMethylationEPIC array with minfi
inferredcites →https://doi.org/10.1093/biostatistics/kxj037openalex-snapshot
Adjusting batch effects in microarray expression data using empirical Bayes methods
inferredcites →https://doi.org/10.1093/gerona/glp163openalex-snapshot
Red Cell Distribution Width and Mortality in Older Adults: A Meta-analysis
inferredcites →https://doi.org/10.1093/infdis/jiv277openalex-snapshot
HIV-1 Infection Accelerates Age According to the Epigenetic Clock
inferredcites →https://doi.org/10.1101/529990openalex-snapshot
Activity-by-Contact model of enhancer specificity from thousands of CRISPR perturbations
inferredcites →https://doi.org/10.1101/531210openalex-snapshot
The mutational constraint spectrum quantified from variation in 141,456 humans
inferredcites →https://doi.org/10.1126/science.aag1381openalex-snapshot
Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice
inferredcites →https://doi.org/10.1182/blood-2005-12-5022openalex-snapshot
Variants in the ATM-BRCA2-CHEK2 axis predispose to chronic lymphocytic leukemia
inferredcites →https://doi.org/10.1182/blood-2015-03-631747openalex-snapshot
Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
inferredcites →https://doi.org/10.1182/blood-2015-06-652941openalex-snapshot
Germ line variants predispose to both JAK2 V617F clonal hematopoiesis and myeloproliferative neoplasms
inferredcites →https://doi.org/10.1182/blood-2017-02-769869openalex-snapshot
Clonal hematopoiesis, with and without candidate driver mutations, is common in the elderly
inferredcites →https://doi.org/10.1186/1471-2105-13-86openalex-snapshot
DNA methylation arrays as surrogate measures of cell mixture distribution
inferredcites →https://doi.org/10.18637/jss.v067.i01openalex-snapshot
Fitting Linear Mixed-Effects Models Using lme4

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.ajhg.2020.07.012openalex-snapshot
Response to Holstege et al.
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2020.02.008openalex-snapshot
Clonal hematopoiesis driven by somatic mutations: A new player in atherosclerotic cardiovascular disease
inferred← citeshttps://doi.org/10.1016/j.cell.2020.08.030openalex-snapshot
Unraveling Hematopoiesis through the Lens of Genomics
inferred← citeshttps://doi.org/10.1016/j.celrep.2020.108326openalex-snapshot
TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity
inferred← citeshttps://doi.org/10.1016/j.exphem.2022.03.008openalex-snapshot
Combination strategies to promote sensitivity to cytarabine-induced replication stress in acute myeloid leukemia with and without DNMT3A mutations
inferred← citeshttps://doi.org/10.1016/j.stem.2020.07.011openalex-snapshot
Sowing the Seeds of Clonal Hematopoiesis
inferred← citeshttps://doi.org/10.1038/s41420-023-01590-zopenalex-snapshot
Clonal haematopoiesis - a novel entity that modifies pathological processes in elderly
inferred← citeshttps://doi.org/10.1038/s41588-020-00710-0openalex-snapshot
Cancer therapy shapes the fitness landscape of clonal hematopoiesis
inferred← citeshttps://doi.org/10.1093/eurheartj/ehaa845openalex-snapshot
Clonal haematopoiesis in chronic ischaemic heart failure: prognostic role of clone size for DNMT3A - and TET2 -driver gene mutations
inferred← citeshttps://doi.org/10.1101/2020.09.01.278093openalex-snapshot
Genome-wide maps of enhancer regulation connect risk variants to disease genes
inferred← citeshttps://doi.org/10.1101/2022.01.17.22269409openalex-snapshot
Clonal hematopoiesis and risk of chronic liver disease
inferred← citeshttps://doi.org/10.1101/790626openalex-snapshot
Genetic predisposition to myeloproliferative neoplasms implicates hematopoietic stem cell biology
inferred← citeshttps://doi.org/10.1111/joim.13130openalex-snapshot
The role of clonal haematopoiesis in cardiovascular diseases: epidemiology and experimental studies
inferred← citeshttps://doi.org/10.1161/circulationaha.119.044362openalex-snapshot
Genetic Interleukin 6 Signaling Deficiency Attenuates Cardiovascular Risk in Clonal Hematopoiesis
inferred← citeshttps://doi.org/10.1161/jaha.120.018789openalex-snapshot
Healthy Lifestyle and Clonal Hematopoiesis of Indeterminate Potential: Results From the Women's Health Initiative
inferred← citeshttps://doi.org/10.1172/jci.insight.135204openalex-snapshot
Tet2-mediated clonal hematopoiesis in nonconditioned mice accelerates age-associated cardiac dysfunction
inferred← citeshttps://doi.org/10.1182/blood.2019000989openalex-snapshot
Clonal hematopoiesis and non-hematologic disorders
inferred← citeshttps://doi.org/10.1182/blood.2020005118openalex-snapshot
The double-edged sword of AlloHCT for SCD
inferred← citeshttps://doi.org/10.1182/blood.2020008206openalex-snapshot
Contribution of clonal hematopoiesis to adult-onset hemophagocytic lymphohistiocytosis
inferred← citeshttps://doi.org/10.1182/blood.2021013531openalex-snapshot
Association of clonal hematopoiesis with chronic obstructive pulmonary disease
inferred← citeshttps://doi.org/10.1182/bloodadvances.2019000770openalex-snapshot
High-sensitivity C-reactive protein is associated with clonal hematopoiesis of indeterminate potential
inferred← citeshttps://doi.org/10.3390/ijms21217902openalex-snapshot
Clonal Hematopoiesis, Cardiovascular Diseases and Hematopoietic Stem Cells
inferred← citeshttps://doi.org/10.3390/jcm9082480openalex-snapshot
Translating Evidence from Clonal Hematopoiesis to Cardiovascular Disease: A Systematic Review
inferred← citeshttps://doi.org/10.7554/elife.96150.1openalex-snapshot
Comprehensive Evaluation of Clonal Hematopoiesis and Mosaic Loss of Y Chromosome in Cardiovascular Risk: A Thorough Analysis in prospective studies
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