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Identification of risk variants and characterization of the polygenic architecture of disruptive behavior disorders in the context of ADHD

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Hyperactive Boys Almost Grown Up
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Genome-Wide Association Studies of a Broad Spectrum of Antisocial Behavior
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School Outcomes of Aggressive‐Disruptive Children: Prediction From Kindergarten Risk Factors and Impact of the Fast Track Prevention Program
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Conduct disorder and ADHD: Evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study
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A genome‐wide approach to children's aggressive behavior: The EAGLE consortium
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Gene‐set and multivariate genome‐wide association analysis of oppositional defiant behavior subtypes in attention‐deficit/hyperactivity disorder
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Longitudinal heritability of childhood aggression
inferredcites →https://doi.org/10.1002/ajmg.b.32434openalex-snapshot
Genome‐wide analyses of aggressiveness in attention‐deficit hyperactivity disorder
inferredcites →https://doi.org/10.1002/ajmg.b.32709openalex-snapshot
Genomics of body fat percentage may contribute to sex bias in anorexia nervosa
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Does the prevalence of CD and ODD vary across cultures?
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Co-transmission of conduct problems with attention-deficit/hyperactivity disorder: familial evidence for a distinct disorder
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Understanding the Covariation Among Childhood Externalizing Symptoms: Genetic and Environmental Influences on Conduct Disorder, Attention Deficit Hyperactivity Disorder, and Oppositional Defiant Disorder Symptoms
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Long-Range LD Can Confound Genome Scans in Admixed Populations
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GCTA: A Tool for Genome-wide Complex Trait Analysis
inferredcites →https://doi.org/10.1016/j.ajhg.2015.12.022openalex-snapshot
Fast Principal-Component Analysis Reveals Convergent Evolution of ADH1B in Europe and East Asia
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Overexpression of STIM1 in neurons in mouse brain improves contextual learning and impairs long-term depression
inferredcites →https://doi.org/10.1016/j.ceca.2019.02.002openalex-snapshot
Numbers count: How STIM and Orai stoichiometry affect store-operated calcium entry
inferredcites →https://doi.org/10.1016/j.cpr.2016.03.001openalex-snapshot
Risky decision making in Attention-Deficit/Hyperactivity Disorder: A meta-regression analysis
inferredcites →https://doi.org/10.1016/j.euroneuro.2018.08.001openalex-snapshot
Live fast, die young? A review on the developmental trajectories of ADHD across the lifespan
inferredcites →https://doi.org/10.1016/j.jaac.2016.06.016openalex-snapshot
Long-Term Outcomes of Attention-Deficit/Hyperactivity Disorder and Conduct Disorder: A Systematic Review and Meta-Analysis
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Expression of STIM1 in brain and puncta-like co-localization of STIM1 and ORAI1 upon depletion of Ca2+ store in neurons
inferredcites →https://doi.org/10.1016/j.neuron.2018.03.017openalex-snapshot
Calcium Channels, Synaptic Plasticity, and Neuropsychiatric Disease
inferredcites →https://doi.org/10.1016/s0140-6736(12)62129-1openalex-snapshot
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
inferredcites →https://doi.org/10.1016/s0140-6736(14)61684-6openalex-snapshot
Mortality in children, adolescents, and adults with attention deficit hyperactivity disorder: a nationwide cohort study
inferredcites →https://doi.org/10.1017/s0021963098002996openalex-snapshot
Familial Subtypes of Attention Deficit Hyperactivity Disorder: A 4-year Follow-up Study of Children from Antisocial-ADHD Families
inferredcites →https://doi.org/10.1017/s0033291700014707openalex-snapshot
Separation of DSM-III attention deficit disorder and conduct disorder: evidence from a family-genetic study of American child psychiatric patients
inferredcites →https://doi.org/10.1017/s003329170003854xopenalex-snapshot
The outcome of childhood conduct disorder: implications for defining adult personality disorder and conduct disorder
inferredcites →https://doi.org/10.1017/s0033291713001396openalex-snapshot
DSM-IV defined conduct disorder and oppositional defiant disorder: an investigation of shared liability in female twins
inferredcites →https://doi.org/10.1023/a:1025735002864openalex-snapshot
Causes of Stability of Aggression from Early Childhood to Adolescence: A Longitudinal Genetic Analysis in Dutch Twins
inferredcites →https://doi.org/10.1037/0012-1649.20.6.1120openalex-snapshot
Stability of aggression over time and generations.
inferredcites →https://doi.org/10.1037/0021-843x.106.2.266openalex-snapshot
Modeling genetic and environmental influences in the etiology of conduct disorder: A study of 2,682 adult twin pairs.
inferredcites →https://doi.org/10.1037/a0029428openalex-snapshot
Sex begets violence: Mating motives, social dominance, and physical aggression in men.
inferredcites →https://doi.org/10.1038/mp.2010.73openalex-snapshot
Genome-wide association study of conduct disorder symptomatology
inferredcites →https://doi.org/10.1038/mp.2013.138openalex-snapshot
Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia
inferredcites →https://doi.org/10.1038/mp.2013.2openalex-snapshot
Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci
inferredcites →https://doi.org/10.1038/mp.2016.259openalex-snapshot
A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder
inferredcites →https://doi.org/10.1038/mp.2016.45openalex-snapshot
Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151)
inferredcites →https://doi.org/10.1038/mp.2017.196openalex-snapshot
The iPSYCH2012 case–cohort sample: new directions for unravelling genetic and environmental architectures of severe mental disorders
inferredcites →https://doi.org/10.1038/mp.2017.98openalex-snapshot
Autism spectrum disorders and autistic traits share genetics and biology
inferredcites →https://doi.org/10.1038/nature04147openalex-snapshot
STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane
inferredcites →https://doi.org/10.1038/nature11632openalex-snapshot
An integrated map of genetic variation from 1,092 human genomes
inferredcites →https://doi.org/10.1038/nature13595openalex-snapshot
Biological insights from 108 schizophrenia-associated genetic loci
inferredcites →https://doi.org/10.1038/nature15393openalex-snapshot
A global reference for human genetic variation
inferredcites →https://doi.org/10.1038/nature15394openalex-snapshot
An integrated map of structural variation in 2,504 human genomes
inferredcites →https://doi.org/10.1038/nature17671openalex-snapshot
Genome-wide association study identifies 74 loci associated with educational attainment
inferredcites →https://doi.org/10.1038/ng.209openalex-snapshot
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder
inferredcites →https://doi.org/10.1038/ng.2653openalex-snapshot
The Genotype-Tissue Expression (GTEx) project
inferredcites →https://doi.org/10.1038/ng.3211openalex-snapshot
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
inferredcites →https://doi.org/10.1038/ng.3367openalex-snapshot
A gene-based association method for mapping traits using reference transcriptome data
inferredcites →https://doi.org/10.1038/ng.3406openalex-snapshot
An atlas of genetic correlations across human diseases and traits
inferredcites →https://doi.org/10.1038/ng.3529openalex-snapshot
Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population
inferredcites →https://doi.org/10.1038/ng.3869openalex-snapshot
Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence
inferredcites →https://doi.org/10.1038/ng1017-1558copenalex-snapshot
Erratum: Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence
inferredcites →https://doi.org/10.1038/ng1847openalex-snapshot
Principal components analysis corrects for stratification in genome-wide association studies
inferredcites →https://doi.org/10.1038/nmeth.1785openalex-snapshot
A linear complexity phasing method for thousands of genomes
inferredcites →https://doi.org/10.1038/nrdp.2015.20openalex-snapshot
Attention-deficit/hyperactivity disorder
inferredcites →https://doi.org/10.1038/s41380-018-0070-0openalex-snapshot
Genetics of attention deficit hyperactivity disorder
inferredcites →https://doi.org/10.1038/s41467-017-02317-2openalex-snapshot
Causal associations between risk factors and common diseases inferred from GWAS summary data
inferredcites →https://doi.org/10.1038/s41572-019-0095-yopenalex-snapshot
Conduct disorder
inferredcites →https://doi.org/10.1038/s41588-018-0269-7openalex-snapshot
Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder
inferredcites →https://doi.org/10.1080/10349120500509992openalex-snapshot
A Genetic Study of Attention Deficit Hyperactivity Disorder, Conduct Disorder, Oppositional Defiant Disorder and Reading Disability: Aetiological overlaps and implications
inferredcites →https://doi.org/10.1086/519795openalex-snapshot
PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses
inferredcites →https://doi.org/10.1093/bioinformatics/btq340openalex-snapshot
METAL: fast and efficient meta-analysis of genomewide association scans
inferredcites →https://doi.org/10.1093/bioinformatics/btz633openalex-snapshot
RICOPILI: Rapid Imputation for COnsortias PIpeLIne
inferredcites →https://doi.org/10.1097/00004583-199701000-00013openalex-snapshot
Is ADHD a Risk Factor for Psychoactive Substance Use Disorders? Findings From a Four-Year Prospective Follow-up Study
inferredcites →https://doi.org/10.1097/00005053-200104000-00001openalex-snapshot
Genetic and Environmental Factors in Conduct Problems and Adult Antisocial Behavior among Adult Female Twins
inferredcites →https://doi.org/10.1097/01.alc.0000141822.36776.55openalex-snapshot
Genetic and Environmental Effects on Conduct Disorder and Alcohol Dependence Symptoms and Their Covariation at Age 14
inferredcites →https://doi.org/10.1101/528117openalex-snapshot
Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders
inferredcites →https://doi.org/10.1111/add.12188openalex-snapshot
Substance use disorders in adolescents with attention deficit hyperactivity disorder: a 4-year follow-up study
inferredcites →https://doi.org/10.1111/j.1469-7610.2004.00250.xopenalex-snapshot
Conduct Disorder and Oppositional Defiant Disorder in a national sample: developmental epidemiology
inferredcites →https://doi.org/10.1111/j.1469-7610.2007.01733.xopenalex-snapshot
Lifetime prevalence, correlates, and persistence of oppositional defiant disorder: results from the National Comorbidity Survey Replication
inferredcites →https://doi.org/10.1176/appi.ajp.2013.12081129openalex-snapshot
High Loading of Polygenic Risk for ADHD in Children With Comorbid Aggression
inferredcites →https://doi.org/10.1177/1403494810395825openalex-snapshot
The Danish Psychiatric Central Research Register
inferredcites →https://doi.org/10.1186/1471-2156-12-58openalex-snapshot
Robustness of genome-wide scanning using archived dried blood spot samples as a DNA source
inferredcites →https://doi.org/10.1186/s13742-015-0047-8openalex-snapshot
Second-generation PLINK: rising to the challenge of larger and richer datasets
inferredcites →https://doi.org/10.1192/bjp.179.3.224openalex-snapshot
Examining the comorbidity of ADHD-related behaviours and conduct problems using a twin study design
inferredcites →https://doi.org/10.1192/bjp.181.5.416openalex-snapshot
Conduct problems, gender and adult psychiatric outcome of children with attention-deficit hyperactivity disorder
inferredcites →https://doi.org/10.1371/journal.pcbi.1004219openalex-snapshot
MAGMA: Generalized Gene-Set Analysis of GWAS Data
inferredcites →https://doi.org/10.1371/journal.pone.0062594openalex-snapshot
Childhood Hyperactivity, Physical Aggression and Criminality: A 19-Year Prospective Population-Based Study
inferredcites →https://doi.org/10.1534/g3.111.001198openalex-snapshot
Genotype Imputation with Thousands of Genomes
inferredcites →https://doi.org/10.1542/peds.2010-0165openalex-snapshot
Patterns of Comorbidity, Functioning, and Service Use for US Children With ADHD, 2007
inferredcites →https://doi.org/10.3389/fnbeh.2015.00180openalex-snapshot
Impaired spatial memory and enhanced long-term potentiation in mice with forebrain-specific ablation of the Stim genes
inferredcites →https://doi.org/10.34944/dspace/4648openalex-snapshot
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics
inferredcites →https://doi.org/10.7334/psicothema2016.294openalex-snapshot
Aggressive behavior in adolescence as a predictor of personal, family, and school adjustment problems

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): II. Externalizing superspectrum
inferred← citeshttps://doi.org/10.1016/j.euroneuro.2019.12.113openalex-snapshot
Special Issue on the Neurobiology of aggressive behaviour in the context of ADHD and related disorders
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Systematic Review: Molecular Studies of Common Genetic Variation in Child and Adolescent Psychiatric Disorders
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2022.104949openalex-snapshot
The translational genetics of ADHD and related phenotypes in model organisms
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Psychological Underpinnings
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The Psychology of Violent Behavior
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Neurobiology of attention-deficit hyperactivity disorder: historical challenges and emerging frontiers
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A Rare Presentation of Hyperphagia and Parasomnias Associated With Chromosome 4q Deletion: A Case Report
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