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p53 isoforms can regulate p53 transcriptional activity

https://doi.org/10.1101/gad.1339905
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/humu.10172openalex-snapshot
TP53 family members and human cancers
inferredcites →https://doi.org/10.1002/j.1460-2075.1985.tb04067.xopenalex-snapshot
The 5′ region of the p53 gene: evolutionary conservation and evidence for a negative regulatory element.
inferredcites →https://doi.org/10.1002/j.1460-2075.1994.tb06808.xopenalex-snapshot
Wild‐type alternatively spliced p53: binding to DNA and interaction with the major p53 protein in vitro and in cells.
inferredcites →https://doi.org/10.1006/jmbi.1995.0202openalex-snapshot
Characterisation of Epitopes on Human p53 using Phage-displayed Peptide Libraries: Insights into Antibody-Peptide Interactions
inferredcites →https://doi.org/10.1006/jmbi.2001.5082openalex-snapshot
Biological significance of a small highly conserved region in the N terminus of the p53 tumour suppressor protein
inferredcites →https://doi.org/10.1016/0042-6822(79)90250-2openalex-snapshot
Identification of new polypeptide species (48–55K) immunoprecipitable by antiserum to purified large T antigen and present in SV40-infected and -transformed cells
inferredcites →https://doi.org/10.1016/0092-8674(74)90154-8openalex-snapshot
Arrangement of specific oligonucleotides within poly(A) terminated HnRNA molecules
inferredcites →https://doi.org/10.1016/0092-8674(79)90293-9openalex-snapshot
Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells
inferredcites →https://doi.org/10.1016/0753-3322(89)90130-3openalex-snapshot
Antibodies, a laboratory manual
inferredcites →https://doi.org/10.1016/j.cell.2004.06.016openalex-snapshot
Mdm2-Mediated NEDD8 Conjugation of p53 Inhibits Its Transcriptional Activity
inferredcites →https://doi.org/10.1016/j.tibs.2003.10.004openalex-snapshot
Functional regulation of p73 and p63: development and cancer
inferredcites →https://doi.org/10.1016/s0092-8674(00)80626-1openalex-snapshot
Drosophila p53 Is a Structural and Functional Homolog of the Tumor Suppressor p53
inferredcites →https://doi.org/10.1016/s0092-8674(00)80627-3openalex-snapshot
Drosophila p53 Binds a Damage Response Element at the reaper Locus
inferredcites →https://doi.org/10.1016/s0168-9525(02)02595-7openalex-snapshot
On the shoulders of giants: p63, p73 and the rise of p53
inferredcites →https://doi.org/10.1038/278261a0openalex-snapshot
T antigen is bound to a host protein in SY40-transformed cells
inferredcites →https://doi.org/10.1038/415045aopenalex-snapshot
p53 mutant mice that display early ageing-associated phenotypes
inferredcites →https://doi.org/10.1038/ncb801openalex-snapshot
p53 stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation products
inferredcites →https://doi.org/10.1038/sj.cdd.4401183openalex-snapshot
Decision making by p53: life, death and cancer
inferredcites →https://doi.org/10.1038/sj.emboj.7600550openalex-snapshot
The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor
inferredcites →https://doi.org/10.1038/sj.onc.1203673openalex-snapshot
p53-dependent apoptosis is regulated by a C-terminally alternatively spliced form of murine p53
inferredcites →https://doi.org/10.1038/sj.onc.1203960openalex-snapshot
Direct transactivation of c-Ha-Ras gene by p53: evidence for its involvement in p53 transactivation activity and p53-mediated apoptosis
inferredcites →https://doi.org/10.1038/sj.onc.1204427openalex-snapshot
p63α and ΔNp63α can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes
inferredcites →https://doi.org/10.1038/sj.onc.1205874openalex-snapshot
ΔN-p53, a natural isoform of p53 lacking the first transactivation domain, counteracts growth suppression by wild-type p53
inferredcites →https://doi.org/10.1073/pnas.012283399openalex-snapshot
Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo
inferredcites →https://doi.org/10.1073/pnas.76.5.2420openalex-snapshot
Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse.
inferredcites →https://doi.org/10.1073/pnas.97.13.7301openalex-snapshot
Identification and characterization of a p53 homologue in Drosophila melanogaster
inferredcites →https://doi.org/10.1074/jbc.273.21.13030openalex-snapshot
Identification of a Novel p53 Functional Domain That Is Necessary for Mediating Apoptosis
inferredcites →https://doi.org/10.1074/jbc.m005676200openalex-snapshot
Definition of the p53 Functional Domains Necessary for Inducing Apoptosis
inferredcites →https://doi.org/10.1083/jcb.200203006openalex-snapshot
Scotin, a novel p53-inducible proapoptotic protein located in the ER and the nuclear membrane
inferredcites →https://doi.org/10.1101/gad.1162404openalex-snapshot
Modulation of mammalian life span by the short isoform of p53
inferredcites →https://doi.org/10.1128/jvi.31.2.472-483.1979openalex-snapshot
Simian virus 40-transformed cells express new species of proteins precipitable by anti-simian virus 40 tumor serum
inferredcites →https://doi.org/10.1128/mcb.24.18.7987-7997.2004openalex-snapshot
Regulation of Human p53 Activity and Cell Localization by Alternative Splicing
inferredcites →https://doi.org/10.1128/mcb.24.2.487-501.2004openalex-snapshot
ΔNp73β Is Active in Transactivation and Growth Suppression
inferredcites →https://doi.org/10.1128/mcb.25.5.2014-2030.2005openalex-snapshot
The C Terminus of p53 Family Proteins Is a Cell Fate Determinant
inferredcites →https://doi.org/10.1128/mcb.5.1.127openalex-snapshot
Isolation of a Full-Length Mouse cDNA Clone Coding for an Immunologically Distinct p53 Molecule
inferredcites →https://doi.org/10.1128/mcb.6.5.1379openalex-snapshot
Characterization of the Human p53 Gene
inferredcites →https://doi.org/10.1242/jcs.01704openalex-snapshot
The neurogene BTG2TIS21/PC3 is transactivated by ΔNp73α via p53 specifically in neuroblastoma cells
inferredcites →https://doi.org/10.1242/jcs.101.1.183openalex-snapshot
Analysis of p53 expression in human tumours: an antibody raised against human p53 expressed in Escherichia coli

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Computational insights into Sitahe (Leuconotis eugenifolia) bioactive compounds: A promising approach for radioprotection through p53 inhibition
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Small Molecule Inhibition of HDM2 Leads to p53-Mediated Cell Death in Retinoblastoma Cells
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Effect of p53 and its N‐terminally truncated isoform, Δ40p53, on breast cancer migration and invasion
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p 53 Family Pathway in Cancer
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Regulation of the p53 Tumor‐Suppressor Protein by Ubiquitin and Ubiquitin‐Like Molecules
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Regulation of the p53 Tumor‐Suppressor Protein by Ubiquitin and Ubiquitin‐Like Molecules
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P53 protein overexpression in de novo acute myeloid leukemia patients with normal diploid karyotype correlates with FLT3 internal tandem duplication and worse relapse‐free survival
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Expression of p53 protein isoforms predicts survival in patients with multiple myeloma
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Advances in the translational genomics of neuroblastoma: From improving risk stratification and revealing novel biology to identifying actionable genomic alterations
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The Role of p53‐Mediated Cellular Senescence in Idiopathic Pulmonary Fibrosis
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Role of p53 family members during development of striated muscle, with focus on p63
inferred← citeshttps://doi.org/10.1002/hep.23746openalex-snapshot
Direct Activation of Forkhead Box O3 by Tumor Suppressors p53 and p73 Is Disrupted During Liver Regeneration in Mice†,‡
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Does the nonsense-mediated mRNA decay mechanism prevent the synthesis of truncated BRCA1, CHK2, and p53 proteins?
inferred← citeshttps://doi.org/10.1002/humu.21214openalex-snapshot
ΔN133p53 expression levels in relation to haplotypes of the TP53 internal promoter region
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Analysis of TP53 Mutation Status in Human Cancer Cell Lines: A Reassessment
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Recommendations for Analyzing and ReportingTP53Gene Variants in the High-Throughput Sequencing Era
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TheTP53Gene Network in a Postgenomic Era
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In vivo evaluation of the role of DNp73α protein in regulating the p53‐dependent apoptotic pathway after treatment with cytotoxic drugs
inferred← citeshttps://doi.org/10.1002/ijc.30003openalex-snapshot
Aberrant splicing of the DMP1 ‐ ARF ‐ MDM2 ‐p53 pathway in cancer
inferred← citeshttps://doi.org/10.1002/ijc.32743openalex-snapshot
GD2‐directed CAR‐T cells in combination with HGF‐targeted neutralizing antibody (AMG102) prevent primary tumor growth and metastasis in Ewing sarcoma
inferred← citeshttps://doi.org/10.1002/jcp.20818openalex-snapshot
Deregulation of cyclin E meets dysfunction in p53: Closing the escape hatch on breast cancer
inferred← citeshttps://doi.org/10.1002/jcp.20829openalex-snapshot
The role of p63 in germ cell apoptosis in the developing testis
inferred← citeshttps://doi.org/10.1002/jcp.26912openalex-snapshot
The role of DEAD‐box RNA helicase p68 (DDX5) in the development and treatment of breast cancer
inferred← citeshttps://doi.org/10.1002/jgm.3063openalex-snapshot
TP53 somatic mutations are associated with somatic mitogenome substitutions but not indels in colorectal cancer cells
inferred← citeshttps://doi.org/10.1002/mc.20337openalex-snapshot
p63: Defining roles in morphogenesis, homeostasis, and neoplasia of the epidermis
inferred← citeshttps://doi.org/10.1002/mc.20537openalex-snapshot
Li–Fraumeni and Li–Fraumeni‐like syndrome mutations in p53 are associated with exonic methylation and splicing regulatory elements
inferred← citeshttps://doi.org/10.1002/mc.22441openalex-snapshot
Damage‐inducible intragenic demethylation of the human TP53 tumor suppressor gene is associated with transcription from an alternative intronic promoter
inferred← citeshttps://doi.org/10.1002/path.1913openalex-snapshot
Assessing p53 in clinical contexts: unlearned lessons and new perspectives
inferred← citeshttps://doi.org/10.1002/path.2086openalex-snapshot
p53: at the crossroad between cancer and ageing
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Tumour suppression by p53: the importance of apoptosis and cellular senescence
inferred← citeshttps://doi.org/10.1002/path.2637openalex-snapshot
Massively regulated genes: the example of TP53
inferred← citeshttps://doi.org/10.1002/path.2652openalex-snapshot
An introduction to genes, genomes and disease
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p53 transcriptional pathways in breast cancer: the good, the bad and the complex
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The role of mutant p53 in human cancer
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Elevation of the TP53 isoform Δ133p53β in glioblastomas: an alternative to mutant p53 in promoting tumor development
inferred← citeshttps://doi.org/10.1002/prca.201200003openalex-snapshot
Fludarabine nucleoside induces accumulations of p53, p63 and p73 in the nuclei of human B ‐lymphoid cell lines, with cytosolic and mitochondrial increases in p53
inferred← citeshttps://doi.org/10.1002/pro.4684openalex-snapshot
Evolution of affinity between p53 transactivation domain and MDM2 across the animal kingdom demonstrates high plasticity of motif‐mediated interactions
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Natural Modulators of the TP53 Pathway: Potential Herbal and Plant‐Derived Agents for Cancer Therapy
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Targeting RNA G-Quadruplexes for Potential Therapeutic Applications
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Role of TP53 Mutations in Cancer (An Overview)
inferred← citeshttps://doi.org/10.1007/978-1-4419-6676-6_10openalex-snapshot
Ubiquitin Family Members in the Regulation of the Tumor Suppressor p53
inferred← citeshttps://doi.org/10.1007/978-1-4419-7203-3_12openalex-snapshot
p63 in Squamous Differentiation and Cancer
inferred← citeshttps://doi.org/10.1007/978-1-4614-7696-2_25openalex-snapshot
Stem Cells and Aging
inferred← citeshttps://doi.org/10.1007/978-1-4939-8876-1_6openalex-snapshot
Detection and Functional Analysis of TP53 Mutations in CLL
inferred← citeshttps://doi.org/10.1007/978-1-59745-169-7_2openalex-snapshot
Integration of Genomics and Proteomics in Dissecting p53 Signaling
inferred← citeshttps://doi.org/10.1007/978-1-59745-510-7_8openalex-snapshot
Medulloblastoma, Primitive Neuroectodermal Tumors, and Pineal Tumors
inferred← citeshttps://doi.org/10.1007/978-1-60327-553-8_14openalex-snapshot
p53 Pathway Alterations in Brain Tumors
inferred← citeshttps://doi.org/10.1007/978-1-62703-236-0_1openalex-snapshot
Detecting and Quantifying p53 Isoforms at mRNA Level in Cell Lines and Tissues
inferred← citeshttps://doi.org/10.1007/978-1-62703-236-0_2openalex-snapshot
Detecting p53 Isoforms at Protein Level
inferred← citeshttps://doi.org/10.1007/978-1-62703-239-1_3openalex-snapshot
Senescence Regulation by the p53 Protein Family
inferred← citeshttps://doi.org/10.1007/978-3-030-55743-0_19openalex-snapshot
Molecular Pathology of Lung Tumors
inferred← citeshttps://doi.org/10.1007/978-3-031-91697-7_19openalex-snapshot
Molecular Pathology of Lung Tumors
inferred← citeshttps://doi.org/10.1007/978-3-642-00150-5_23openalex-snapshot
p53
inferred← citeshttps://doi.org/10.1007/978-3-642-31659-3_3openalex-snapshot
Cancer-Associated Perturbations in Alternative Pre-messenger RNA Splicing
inferred← citeshttps://doi.org/10.1007/978-3-662-50491-8_19openalex-snapshot
Molecular Pathology of Lung Tumors
inferred← citeshttps://doi.org/10.1007/978-94-017-9211-0_2openalex-snapshot
Alterations of p63 and p73 in Human Cancers
inferred← citeshttps://doi.org/10.1007/978-94-017-9211-0_3openalex-snapshot
Cooperation of p53 Mutations with Other Oncogenic Alterations in Cancer
inferred← citeshttps://doi.org/10.1007/978-94-017-9421-3_4openalex-snapshot
p53 at the Crossroads Between Stress Response Signaling and Tumorigenesis: From Molecular Mechanisms to Therapeutic Opportunities
inferred← citeshttps://doi.org/10.1007/978-94-017-9639-2_8openalex-snapshot
Sentinel Gene Within Cell Territory and Molecular Platforms in Cancer: Methylation Diversity of p53 Gene in Brain Tumors
inferred← citeshttps://doi.org/10.1007/s00018-008-8336-3openalex-snapshot
p53 isoforms - A conspiracy to kidnap p53 tumor suppressor activity?
inferred← citeshttps://doi.org/10.1007/s00239-008-9124-2openalex-snapshot
Biochemical and Functional Evidence of p53 Homology Is Inconsistent with Molecular Phylogenetics for Distant Sequences
inferred← citeshttps://doi.org/10.1007/s00262-008-0639-6openalex-snapshot
Why do centenarians escape or postpone cancer? The role of IGF-1, inflammation and p53
inferred← citeshttps://doi.org/10.1007/s00335-018-9758-3openalex-snapshot
A mouse model of the Δ133p53 isoform: roles in cancer progression and inflammation
inferred← citeshttps://doi.org/10.1007/s00795-012-0575-6openalex-snapshot
Overexpression of p53 protein in human tumors
inferred← citeshttps://doi.org/10.1007/s10126-006-6045-1openalex-snapshot
Identification of DeltaN Isoform and Polyadenylation Site Choice Variants in Molluscan p63/p73-Like Homologues
inferred← citeshttps://doi.org/10.1007/s10495-010-0456-1openalex-snapshot
Regulating the genome surveillance system: miRNAs and the p53 super family
inferred← citeshttps://doi.org/10.1007/s10495-014-1000-5openalex-snapshot
Drosophila p53 controls Notch expression and balances apoptosis and proliferation
inferred← citeshttps://doi.org/10.1007/s10495-014-1035-7openalex-snapshot
The p53 control of apoptosis and proliferation: lessons from Drosophila
inferred← citeshttps://doi.org/10.1007/s10528-025-11180-6openalex-snapshot
Decoding the Transcriptional Complexity of the Human BRCA2 DNA Repair Gene Using Hybrid-seq
inferred← citeshttps://doi.org/10.1007/s10549-007-9514-yopenalex-snapshot
G:C > A:T mutations and potential epigenetic regulation of p53 in breast cancer
inferred← citeshttps://doi.org/10.1007/s10585-009-9278-3openalex-snapshot
Allelic loss at TP53 in metastatic human endometrial carcinomas
inferred← citeshttps://doi.org/10.1007/s10689-018-0075-5openalex-snapshot
The first two confirmed sub-Saharan African families with germline TP53 mutations causing Li-Fraumeni syndrome
inferred← citeshttps://doi.org/10.1007/s11010-006-9374-5openalex-snapshot
Loss of heterozygosity of the p53 gene and deregulated expression of its mRNA and protein in human brain tumors
inferred← citeshttps://doi.org/10.1007/s11010-018-3461-2openalex-snapshot
AG1031 induces apoptosis through suppressing SIRT1/p53 pathway in human neuroblastoma cells
inferred← citeshttps://doi.org/10.1007/s11033-010-0569-1openalex-snapshot
The characterization of two novel IRF-3 transcripts starting from intron 2 of the wild type of IRF-3
inferred← citeshttps://doi.org/10.1007/s11033-012-1528-9openalex-snapshot
Characterization of a spliced variant of human IRF-3 promoter and its regulation by the transcription factor Sp1
inferred← citeshttps://doi.org/10.1007/s11033-012-1798-2openalex-snapshot
Splicing of mouse p53 pre-mRNA does not always follow the “first come, first served” principle and may be influenced by cisplatin treatment and serum starvation
inferred← citeshttps://doi.org/10.1007/s11033-024-10051-4openalex-snapshot
Role of artificial intelligence in cancer detection using protein p53: A Review
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Circular RNA role in Atherosclerosis Development and Progression
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Small Interfering RNA (siRNA) for Cardiorenal Disease: Mechanistic Insights from Preclinical and Clinical Studies
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Navigating the complexity of p53-DNA binding: implications for cancer therapy
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(Intrinsically disordered) splice variants in the proteome: implications for novel drug discovery
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Current understanding of the role and targeting of tumor suppressor p53 in glioblastoma multiforme
inferred← citeshttps://doi.org/10.1007/s13353-014-0239-4openalex-snapshot
Splice-acceptor site mutation in p53 gene of hu888 zebrafish line
inferred← citeshttps://doi.org/10.1007/s13370-026-01450-wopenalex-snapshot
A mathematical perspective into the p53 protein on the expression of the transcription factor E2F in CycD/Cdk4(6) subsystem
inferred← citeshttps://doi.org/10.1016/b978-0-12-374145-5.00264-3openalex-snapshot
Signaling to the p53 Tumor Suppressor through Pathways Activated by Genotoxic and Non-Genotoxic Stresses
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The Role of Alternative Splicing During the Cell Cycle and Programmed Cell Death
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The Molecular Biology of Cancer
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Theranostics in gastric and colorectal cancer
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MOLECULAR BIOLOGY OF COLORECTAL CANCER
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SPARC-p53: The double agents of cancer
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Understanding the Multifaceted Role of Human Down Syndrome Kinase DYRK1A
inferred← citeshttps://doi.org/10.1016/j.ab.2007.04.003openalex-snapshot
The use of Alu I to destroy DNA contamination in reverse transcription polymerase chain reaction and its advantages
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The calcium binding protein ALG-2 binds and stabilizes Scotin, a p53-inducible gene product localized at the endoplasmic reticulum membrane
inferred← citeshttps://doi.org/10.1016/j.bbagen.2011.11.011openalex-snapshot
Trichostatin A and sirtinol suppressed survivin expression through AMPK and p38MAPK in HT29 colon cancer cells
inferred← citeshttps://doi.org/10.1016/j.bbagen.2013.04.011openalex-snapshot
Simvastatin induced HCT116 colorectal cancer cell apoptosis through p38MAPK-p53-survivin signaling cascade
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2016.06.001openalex-snapshot
p53 represses the transcription of snRNA genes by preventing the formation of little elongation complex
inferred← citeshttps://doi.org/10.1016/j.bbcan.2009.12.001openalex-snapshot
Helpers of the cellular gatekeeper—miRNAs dance in P53 network
inferred← citeshttps://doi.org/10.1016/j.bbcan.2021.188556openalex-snapshot
Tumor suppressor p53: Biology, signaling pathways, and therapeutic targeting
inferred← citeshttps://doi.org/10.1016/j.bbcan.2023.188882openalex-snapshot
The role of truncated p53 isoforms in the DNA damage response
inferred← citeshttps://doi.org/10.1016/j.bbrc.2006.03.128openalex-snapshot
A dominant negative form of p63 inhibits apoptosis in a p53-independent manner
inferred← citeshttps://doi.org/10.1016/j.bbrc.2006.04.120openalex-snapshot
Functional cross-talk between p73β and NF-κB mediated by p300
inferred← citeshttps://doi.org/10.1016/j.bbrc.2006.10.029openalex-snapshot
p53 splice variants generated by atypical mRNA processing confer complexity of p53 transcripts in the human brain
inferred← citeshttps://doi.org/10.1016/j.bbrc.2007.01.057openalex-snapshot
Functional characterization of a new p53 mutant generated by homozygous deletion in a neuroblastoma cell line
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Analysis of p53–RNA interactions in cultured human cells
inferred← citeshttps://doi.org/10.1016/j.bbrc.2008.02.128openalex-snapshot
ΔNp63/BMP-7-dependent expression of matrilin-2 is involved in keratinocyte migration in response to wounding
inferred← citeshttps://doi.org/10.1016/j.bbrc.2011.08.098openalex-snapshot
Alternative splicings on p53, BRCA1 and PTEN genes involved in breast cancer
inferred← citeshttps://doi.org/10.1016/j.bcp.2008.08.030openalex-snapshot
Wild-type p53 in cancer cells: When a guardian turns into a blackguard
inferred← citeshttps://doi.org/10.1016/j.biocel.2010.10.017openalex-snapshot
Co-localization of mutant p53 and amyloid-like protein aggregates in breast tumors
inferred← citeshttps://doi.org/10.1016/j.biocel.2013.12.004openalex-snapshot
Caffeine induces tumor cytotoxicity via the regulation of alternative splicing in subsets of cancer-associated genes
inferred← citeshttps://doi.org/10.1016/j.biochi.2011.06.010openalex-snapshot
The can and can’t dos of p53 RNA
inferred← citeshttps://doi.org/10.1016/j.biochi.2017.02.008openalex-snapshot
Genetic alterations in Krebs cycle and its impact on cancer pathogenesis
inferred← citeshttps://doi.org/10.1016/j.biochi.2022.12.011openalex-snapshot
Interaction of C-terminal p53 isoforms depends strongly upon DNA sequence and topology
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.114786openalex-snapshot
Methods and biomarkers for early detection, prediction, and diagnosis of colorectal cancer
inferred← citeshttps://doi.org/10.1016/j.biosystems.2013.08.004openalex-snapshot
Novel recurrent neural network for modelling biological networks: Oscillatory p53 interaction dynamics
inferred← citeshttps://doi.org/10.1016/j.canep.2026.103204openalex-snapshot
TP53 mutations predict poor breast cancer–specific survival in ER-positive breast cancer patients
inferred← citeshttps://doi.org/10.1016/j.cbpc.2008.09.017openalex-snapshot
Expression analysis of the molluscan p53 protein family mRNA in mussels (Mytilus spp.) exposed to organic contaminants
inferred← citeshttps://doi.org/10.1016/j.ccr.2007.10.001openalex-snapshot
Shaping Genetic Alterations in Human Cancer: The p53 Mutation Paradigm
inferred← citeshttps://doi.org/10.1016/j.cell.2009.04.037openalex-snapshot
Blinded by the Light: The Growing Complexity of p53
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2005.12.005openalex-snapshot
Effects of exogenous p53 transfection on the gene expression in the human brain glioma cell line U251
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2006.05.021openalex-snapshot
Characterization of the human PAP1 gene and its homologue possible involvement in mouse embryonic development
inferred← citeshttps://doi.org/10.1016/j.cub.2006.07.046openalex-snapshot
Compensatory Proliferation in Drosophila Imaginal Discs Requires Dronc-Dependent p53 Activity
inferred← citeshttps://doi.org/10.1016/j.devcel.2018.01.022openalex-snapshot
Innate Immune Response and Off-Target Mis-splicing Are Common Morpholino-Induced Side Effects in Xenopus
inferred← citeshttps://doi.org/10.1016/j.dnarep.2006.01.006openalex-snapshot
Cellular responses to DNA damage: Current state of the field and review of the 52nd Benzon Symposium
inferred← citeshttps://doi.org/10.1016/j.dnarep.2007.12.007openalex-snapshot
DNA repair, damage signaling and carcinogenesis
inferred← citeshttps://doi.org/10.1016/j.dnarep.2009.01.008openalex-snapshot
p53 ubiquitination by Mdm2: A never ending tail?
inferred← citeshttps://doi.org/10.1016/j.dnarep.2011.10.016openalex-snapshot
TAp63γ enhances nucleotide excision repair through transcriptional regulation of DNA repair genes
inferred← citeshttps://doi.org/10.1016/j.drup.2007.01.001openalex-snapshot
One, two, three—p53, p63, p73 and chemosensitivity
inferred← citeshttps://doi.org/10.1016/j.ejca.2006.10.019openalex-snapshot
Expression of p53 isoforms in squamous cell carcinoma of the head and neck
inferred← citeshttps://doi.org/10.1016/j.ejca.2007.01.042openalex-snapshot
p73: A chiaroscuro gene in cancer
inferred← citeshttps://doi.org/10.1016/j.ejca.2007.10.011openalex-snapshot
Expression levels of p53 and p73 isoforms in stage I and stage III ovarian cancer
inferred← citeshttps://doi.org/10.1016/j.ejca.2017.06.023openalex-snapshot
Mutant p53 as a target for cancer treatment
inferred← citeshttps://doi.org/10.1016/j.ejcts.2009.12.018openalex-snapshot
Prognostic value of p53 mutations in oesophageal adenocarcinoma: final results of a 15-year prospective study
inferred← citeshttps://doi.org/10.1016/j.ejmech.2018.08.099openalex-snapshot
Role of p53 circuitry in tumorigenesis: A brief review
inferred← citeshttps://doi.org/10.1016/j.exger.2008.05.017openalex-snapshot
Running on empty: How p53 controls INS/IGF signaling and affects life span
inferred← citeshttps://doi.org/10.1016/j.exger.2010.02.007openalex-snapshot
A role for p53 in mitochondrial stress response control of longevity in C. elegans
inferred← citeshttps://doi.org/10.1016/j.fct.2025.115505openalex-snapshot
Cr (VI) induces lactate utilization through HIF-1α/MCT1 dependent on p53 protein level
inferred← citeshttps://doi.org/10.1016/j.febslet.2007.11.013openalex-snapshot
SuPr‐1‐mediated desumoylation regulates the repressor activity of ΔNp63α
inferred← citeshttps://doi.org/10.1016/j.febslet.2009.09.057openalex-snapshot
Polo‐like kinase‐1 phosphorylates MDM2 at Ser260 and stimulates MDM2‐mediated p53 turnover
inferred← citeshttps://doi.org/10.1016/j.febslet.2010.10.005openalex-snapshot
Δ160p53 is a novel N‐terminal p53 isoform encoded by Δ133p53 transcript
inferred← citeshttps://doi.org/10.1016/j.fsi.2017.09.039openalex-snapshot
Mandarin fish p53: Genomic structure, alternatively spliced variant and its mRNA expression after virus challenge
inferred← citeshttps://doi.org/10.1016/j.fsi.2018.10.054openalex-snapshot
c-Jun regulates the promoter of small subunit hemocyanin gene of Litopenaeus vannamei
inferred← citeshttps://doi.org/10.1016/j.gde.2005.12.001openalex-snapshot
p63: oncogene or tumor suppressor?
inferred← citeshttps://doi.org/10.1016/j.gendis.2022.10.014openalex-snapshot
Sonic hedgehog signaling: Alternative splicing and pathogenic role in medulloblastoma
inferred← citeshttps://doi.org/10.1016/j.gene.2006.08.002openalex-snapshot
Tissue-specific alternative promoters of the serotonin receptor gene HTR3B in human brain and intestine
inferred← citeshttps://doi.org/10.1016/j.heliyon.2019.e02624openalex-snapshot
The interplay between Epstein-Bar virus (EBV) with the p53 and its homologs during EBV associated malignancies
inferred← citeshttps://doi.org/10.1016/j.isci.2024.110604openalex-snapshot
Patient-derived tumor organoids mimic treatment-induced DNA damage response in glioblastoma
inferred← citeshttps://doi.org/10.1016/j.jbc.2021.101163openalex-snapshot
Inhibition of nonsense-mediated decay rescues p53β/γ isoform expression and activates the p53 pathway in MDM2-overexpressing and select p53-mutant cancers
inferred← citeshttps://doi.org/10.1016/j.jbiotec.2012.01.006openalex-snapshot
Selective regression of cancer cells expressing a splicing variant of AIMP2 through targeted RNA replacement by trans-splicing ribozyme
inferred← citeshttps://doi.org/10.1016/j.jcpa.2007.04.021openalex-snapshot
A Comprehensive Test System to Identify Suitable Antibodies Against p53 for Immunohistochemical Analysis of Canine Tissues
inferred← citeshttps://doi.org/10.1016/j.jgg.2014.01.001openalex-snapshot
Protein Interaction Between p53 and Δ113p53 Is Required for the Anti-Apoptotic Function of Δ113p53
inferred← citeshttps://doi.org/10.1016/j.jmb.2026.169764openalex-snapshot
Regulation of Eukaryotic Gene Expression Through Functional Coupling Between Alternative Splicing and Nonsense-mediated Decay
inferred← citeshttps://doi.org/10.1016/j.jprot.2012.07.021openalex-snapshot
Leukocyte p53 protein biosignature through standard-aligned two-dimensional immunoblotting
inferred← citeshttps://doi.org/10.1016/j.leukres.2007.06.022openalex-snapshot
Identification of a novel, transactivation-defective splicing variant of p53 gene in patients with chronic lymphocytic leukemia
inferred← citeshttps://doi.org/10.1016/j.leukres.2010.12.016openalex-snapshot
A comprehensive study of TP53 mutations in chronic lymphocytic leukemia: Analysis of 1287 diagnostic and 1148 follow-up CLL samples
inferred← citeshttps://doi.org/10.1016/j.mad.2007.01.001openalex-snapshot
Reassessing the role of p53 in cancer and ageing from an evolutionary perspective
inferred← citeshttps://doi.org/10.1016/j.mad.2007.10.011openalex-snapshot
Aging-associated truncated form of p53 interacts with wild-type p53 and alters p53 stability, localization, and activity
inferred← citeshttps://doi.org/10.1016/j.mad.2008.02.002openalex-snapshot
DNA double-strand breaks: A potential causative factor for mammalian aging?
inferred← citeshttps://doi.org/10.1016/j.mad.2008.06.002openalex-snapshot
Antagonistic pleiotropy and p53
inferred← citeshttps://doi.org/10.1016/j.marenvres.2008.06.004openalex-snapshot
Invertebrate p53-like mRNA isoforms are differentially expressed in mussel haemic neoplasia
inferred← citeshttps://doi.org/10.1016/j.marenvres.2014.09.005openalex-snapshot
The metallothionein gene from the white shrimp Litopenaeus vannamei : Characterization and expression in response to hypoxia
inferred← citeshttps://doi.org/10.1016/j.mod.2008.09.003openalex-snapshot
p53 family in development
inferred← citeshttps://doi.org/10.1016/j.molcel.2006.01.020openalex-snapshot
p53 Ubiquitination: Mdm2 and Beyond
inferred← citeshttps://doi.org/10.1016/j.molcel.2006.05.015openalex-snapshot
Structural Basis of DNA Recognition by p53 Tetramers
inferred← citeshttps://doi.org/10.1016/j.molcel.2010.01.041openalex-snapshot
Endoplasmic Reticulum Stress Induces G2 Cell-Cycle Arrest via mRNA Translation of the p53 Isoform p53/47
inferred← citeshttps://doi.org/10.1016/j.molmed.2007.03.002openalex-snapshot
Classic and novel roles of p53: prospects for anticancer therapy
inferred← citeshttps://doi.org/10.1016/j.mrgentox.2010.06.001openalex-snapshot
Variations in p53-like cDNA sequence are correlated with mussel haemic neoplasia: A potential molecular-level tool for biomonitoring
inferred← citeshttps://doi.org/10.1016/j.mrrev.2008.06.002openalex-snapshot
P53 transcriptional activities: A general overview and some thoughts
inferred← citeshttps://doi.org/10.1016/j.neurobiolaging.2015.06.021openalex-snapshot
The amyloid precursor protein (APP) intracellular domain regulates translation of p44, a short isoform of p53, through an IRES-dependent mechanism
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2022.06.004openalex-snapshot
Δ133p53α Protects Human Astrocytes from Amyloid-beta Induced Senescence and Neurotoxicity
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2025.06.031openalex-snapshot
Δ133p53α-mediated inhibition of astrocyte senescence and neurotoxicity as a possible therapeutic approach for neurodegenerative diseases
inferred← citeshttps://doi.org/10.1016/j.oraloncology.2007.01.014openalex-snapshot
Expression of novel p53 isoforms in oral lichen planus
inferred← citeshttps://doi.org/10.1016/j.pathol.2024.02.003openalex-snapshot
Combining TP53 mutation and isoform has the potential to improve clinical practice
inferred← citeshttps://doi.org/10.1016/j.physd.2024.134348openalex-snapshot
A mathematical treatment of the impact of p53 signalling on the expression of the transcription factor E2F in the CycE/Cdk2 subsystem in cancerous cells
inferred← citeshttps://doi.org/10.1016/j.pneurobio.2018.05.001openalex-snapshot
The interactions of p53 with tau and Aß as potential therapeutic targets for Alzheimer’s disease
inferred← citeshttps://doi.org/10.1016/j.prp.2022.153890openalex-snapshot
New insights into the interactions of HPV-16 E6*I and E6*II with p53 isoforms and induction of apoptosis in cancer-derived cell lines
inferred← citeshttps://doi.org/10.1016/j.sbi.2008.10.002openalex-snapshot
Function and structure of inherently disordered proteins
inferred← citeshttps://doi.org/10.1016/j.semcancer.2010.02.005openalex-snapshot
p53 family members in cancer diagnosis and treatment
inferred← citeshttps://doi.org/10.1016/j.semcancer.2024.08.003openalex-snapshot
Molecular signaling and clinical implications in the human aging-cancer cycle
inferred← citeshttps://doi.org/10.1016/j.semcdb.2015.10.024openalex-snapshot
cncRNAs: Bi-functional RNAs with protein coding and non-coding functions
inferred← citeshttps://doi.org/10.1016/j.semcdb.2017.09.018openalex-snapshot
Alternative splicing in cancers: From aberrant regulation to new therapeutics
inferred← citeshttps://doi.org/10.1016/j.stemcr.2015.02.001openalex-snapshot
The p53 Isoform Δ133p53β Promotes Cancer Stem Cell Potential
inferred← citeshttps://doi.org/10.1016/j.str.2009.11.011openalex-snapshot
Crystal Structure of the p53 Core Domain Bound to a Full Consensus Site as a Self-Assembled Tetramer
inferred← citeshttps://doi.org/10.1016/j.tcb.2008.03.003openalex-snapshot
The impact of p53 and p73 on aneuploidy and cancer
inferred← citeshttps://doi.org/10.1016/j.tibs.2016.08.011openalex-snapshot
The Tail That Wags the Dog: How the Disordered C-Terminal Domain Controls the Transcriptional Activities of the p53 Tumor-Suppressor Protein
inferred← citeshttps://doi.org/10.1016/j.tig.2014.05.005openalex-snapshot
The emerging era of genomic data integration for analyzing splice isoform function
inferred← citeshttps://doi.org/10.1016/j.tranon.2025.102616openalex-snapshot
First functional evidence that a rare germline TP53β variant drives senescence-associated immune suppression and impairs apoptosis and cell migration in breast cancer patients
inferred← citeshttps://doi.org/10.1016/j.trecan.2020.04.011openalex-snapshot
RNA Splicing and Cancer
inferred← citeshttps://doi.org/10.1016/j.tripleo.2008.07.002openalex-snapshot
Prognostic factors and survival analysis in a sample of oral squamous cell carcinoma patients
inferred← citeshttps://doi.org/10.1016/j.urolonc.2019.03.007openalex-snapshot
The role of p53 isoforms’ expression and p53 mutation status in renal cell cancer prognosis
inferred← citeshttps://doi.org/10.1016/j.ydbio.2007.10.004openalex-snapshot
Altered mammary gland development in the p53+/m mouse, a model of accelerated aging
inferred← citeshttps://doi.org/10.1016/j.yexcr.2020.111925openalex-snapshot
Research progress on the effect of autophagy-lysosomal pathway on tumor drug resistance
inferred← citeshttps://doi.org/10.1016/j.ymeth.2015.04.018openalex-snapshot
The variation game: Cracking complex genetic disorders with NGS and omics data
inferred← citeshttps://doi.org/10.1016/j.ymeth.2015.07.016openalex-snapshot
Pushing the annotation of cellular activities to a higher resolution: Predicting functions at the isoform level
inferred← citeshttps://doi.org/10.1016/s1470-2045(09)70198-6openalex-snapshot
30 years and a long way into p53 research
inferred← citeshttps://doi.org/10.1016/s1470-2045(11)70094-8openalex-snapshot
TP53 status for prediction of sensitivity to taxane versus non-taxane neoadjuvant chemotherapy in breast cancer (EORTC 10994/BIG 1-00): a randomised phase 3 trial
inferred← citeshttps://doi.org/10.1016/s1472-6483(10)60105-8openalex-snapshot
Study of p53 gene mutations and placental expression in recurrent miscarriage cases
inferred← citeshttps://doi.org/10.1017/9781107707504.006openalex-snapshot
Molecular genetics of soft tissue tumors
inferred← citeshttps://doi.org/10.1017/cbo9780511781049.006openalex-snapshot
MOLECULAR GENETICS OF SOFT TISSUE TUMORS
inferred← citeshttps://doi.org/10.1021/acs.analchem.7b02890openalex-snapshot
Simultaneous Detection of Human C‑Terminal p53 Isoforms by Single Template Molecularly Imprinted Polymers (MIPs) Coupled with Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)-Based Targeted Proteomics
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