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High constitutive activity of a broad panel of housekeeping and tissue-specific cis-regulatory elements depends on a subset of ETS proteins

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/wdev.21openalex-snapshot
Perspectives on the RNA polymerase II core promoter
inferredcites →https://doi.org/10.1007/s00005-006-0017-zopenalex-snapshot
ETS transcription factors and regulation of immunity
inferredcites →https://doi.org/10.1016/0092-8674(89)90176-1openalex-snapshot
The “initiator” as a transcription control element
inferredcites →https://doi.org/10.1016/j.cell.2012.12.018openalex-snapshot
Latent Enhancers Activated by Stimulation in Differentiated Cells
inferredcites →https://doi.org/10.1016/j.devcel.2016.01.024openalex-snapshot
Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation
inferredcites →https://doi.org/10.1016/j.gene.2006.09.029openalex-snapshot
Prevalence of the initiator over the TATA box in human and yeast genes and identification of DNA motifs enriched in human TATA-less core promoters
inferredcites →https://doi.org/10.1016/j.immuni.2010.02.008openalex-snapshot
Identification and Characterization of Enhancers Controlling the Inflammatory Gene Expression Program in Macrophages
inferredcites →https://doi.org/10.1016/j.molcel.2010.05.004openalex-snapshot
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
inferredcites →https://doi.org/10.1016/j.molcel.2013.07.010openalex-snapshot
Remodeling of the Enhancer Landscape during Macrophage Activation Is Coupled to Enhancer Transcription
inferredcites →https://doi.org/10.1016/j.molcel.2014.04.006openalex-snapshot
Coregulation of Transcription Factor Binding and Nucleosome Occupancy through DNA Features of Mammalian Enhancers
inferredcites →https://doi.org/10.1016/j.molcel.2014.08.004openalex-snapshot
Integrator Regulates Transcriptional Initiation and Pause Release following Activation
inferredcites →https://doi.org/10.1016/j.molcel.2015.09.018openalex-snapshot
Transcription of Mammalian cis-Regulatory Elements Is Restrained by Actively Enforced Early Termination
inferredcites →https://doi.org/10.1016/s0092-8674(03)00887-0openalex-snapshot
Structural Basis of Core Promoter Recognition in a Primitive Eukaryote
inferredcites →https://doi.org/10.1038/emboj.2010.106openalex-snapshot
Genome‐wide analysis of ETS‐family DNA‐binding in vitro and in vivo
inferredcites →https://doi.org/10.1038/emboj.2012.275openalex-snapshot
RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis
inferredcites →https://doi.org/10.1038/msb.2012.23openalex-snapshot
Chromatin measurements reveal contributions of synthesis and decay to steady‐state mRNA levels
inferredcites →https://doi.org/10.1038/nature03441openalex-snapshot
Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals
inferredcites →https://doi.org/10.1038/nature09033openalex-snapshot
Widespread transcription at neuronal activity-regulated enhancers
inferredcites →https://doi.org/10.1038/nature09692openalex-snapshot
A unique chromatin signature uncovers early developmental enhancers in humans
inferredcites →https://doi.org/10.1038/nature10006openalex-snapshot
Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA
inferredcites →https://doi.org/10.1038/nbt.1630openalex-snapshot
GREAT improves functional interpretation of cis-regulatory regions
inferredcites →https://doi.org/10.1038/ncomms6531openalex-snapshot
Integrator complex regulates NELF-mediated RNA polymerase II pause/release and processivity at coding genes
inferredcites →https://doi.org/10.1038/ng.3142openalex-snapshot
Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers
inferredcites →https://doi.org/10.1038/ng1789openalex-snapshot
Genome-wide analysis of mammalian promoter architecture and evolution
inferredcites →https://doi.org/10.1038/ni.3306openalex-snapshot
Molecular control of activation and priming in macrophages
inferredcites →https://doi.org/10.1038/nmeth.2688openalex-snapshot
Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
inferredcites →https://doi.org/10.1038/nmeth.3047openalex-snapshot
Improved vectors and genome-wide libraries for CRISPR screening
inferredcites →https://doi.org/10.1038/nrg3207openalex-snapshot
Transcription factors: from enhancer binding to developmental control
inferredcites →https://doi.org/10.1038/nrg3682openalex-snapshot
Transcriptional enhancers: from properties to genome-wide predictions
inferredcites →https://doi.org/10.1042/bst0341047openalex-snapshot
Perspectives on the RNA polymerase II core promoter
inferredcites →https://doi.org/10.1073/pnas.1016071107openalex-snapshot
Histone H3K27ac separates active from poised enhancers and predicts developmental state
inferredcites →https://doi.org/10.1101/gad.12.1.34openalex-snapshot
New core promoter element in RNA polymerase II-dependent transcription: sequence-specific DNA binding by transcription factor IIB
inferredcites →https://doi.org/10.1101/gad.176826.111openalex-snapshot
Pioneer transcription factors: establishing competence for gene expression
inferredcites →https://doi.org/10.1101/gad.257592.114openalex-snapshot
A dual cis -regulatory code links IRF8 to constitutive and inducible gene expression in macrophages
inferredcites →https://doi.org/10.1101/gad.342405openalex-snapshot
A core promoter element downstream of the TATA box that is recognized by TFIIB
inferredcites →https://doi.org/10.1101/gr.138776.112openalex-snapshot
CpG islands and GC content dictate nucleosome depletion in a transcription-independent manner at mammalian promoters
inferredcites →https://doi.org/10.1101/gr.1953904openalex-snapshot
Clustering of DNA Sequences in Human Promoters
inferredcites →https://doi.org/10.1101/gr.6831208openalex-snapshot
A code for transcription initiation in mammalian genomes
inferredcites →https://doi.org/10.1101/sqb.1978.042.01.105openalex-snapshot
The Organization of the Histone Genes in Drosophila melanogaster: Functional and Evolutionary Implications
inferredcites →https://doi.org/10.1126/science.1256271openalex-snapshot
Chromatin state dynamics during blood formation
inferredcites →https://doi.org/10.1126/science.aac6948openalex-snapshot
Suboptimization of developmental enhancers
inferredcites →https://doi.org/10.1128/mcb.17.6.2973openalex-snapshot
Accurate Positioning of RNA Polymerase II on a Natural TATA-Less Promoter Is Independent of TATA-Binding-Protein-Associated Factors and Initiator-Binding Proteins
inferredcites →https://doi.org/10.1146/annurev.biochem.79.081507.103945openalex-snapshot
Genomic and Biochemical Insights into the Specificity of ETS Transcription Factors
inferredcites →https://doi.org/10.1186/gb-2006-7-7-r53openalex-snapshot
Comparative genomics of Drosophila and human core promoters
inferredcites →https://doi.org/10.1186/gb-2006-7-8-r78openalex-snapshot
Transcriptional and structural impact of TATA-initiation site spacing in mammalian core promoters
inferredcites →https://doi.org/10.1242/dev.106054openalex-snapshot
A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification
inferredcites →https://doi.org/10.1242/dev.114843openalex-snapshot
Chd1 is essential for the high transcriptional output and rapid growth of the mouse epiblast
inferredcites →https://doi.org/10.1371/journal.pbio.1000384openalex-snapshot
A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers
inferredcites →https://doi.org/10.7554/elife.02042openalex-snapshot
The nucleosomal barrier to promoter escape by RNA polymerase II is overcome by the chromatin remodeler Chd1

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4755772openalex-extracted
Cross-Validation of Conserved Osteoblast-Specific Enhancers Illuminates Bone Diseases and Early Skeletal Evolution
inferred← citeshttps://doi.org/10.1007/978-3-319-31143-2_115-1openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/978-3-319-55530-0_115openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s00018-022-04290-6openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s10875-023-01453-3openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s12015-021-10188-wopenalex-snapshot
Stress Decreases Host Viral Resistance and Increases Covid Susceptibility in Embryonic Stem Cells
inferred← citeshttps://doi.org/10.1016/j.cdev.2024.203924openalex-snapshot
Xenopus tropicalis osteoblast-specific open chromatin regions reveal promoters and enhancers involved in human skeletal phenotypes and shed light on early vertebrate evolution
inferred← citeshttps://doi.org/10.1016/j.cell.2018.03.081openalex-snapshot
Co-optation of Tandem DNA Repeats for the Maintenance of Mesenchymal Identity
inferred← citeshttps://doi.org/10.1016/j.devcel.2020.09.011openalex-snapshot
Pancreatic Cancer Cells Require the Transcription Factor MYRF to Maintain ER Homeostasis
inferred← citeshttps://doi.org/10.1016/j.isci.2021.102169openalex-snapshot
Suppression of ELF4 in ulcerative colitis predisposes host to colorectal cancer
inferred← citeshttps://doi.org/10.1016/j.mce.2024.112411openalex-snapshot
Transforming growth factor β-2 is rhythmically expressed in both WT and BMAL1-deficient hypothalamic neurons and regulates neuropeptide Y: Disruption by palmitate
inferred← citeshttps://doi.org/10.1016/j.molcel.2018.07.017openalex-snapshot
Emerging Principles of Gene Expression Programs and Their Regulation
inferred← citeshttps://doi.org/10.1016/j.molcel.2023.12.033openalex-snapshot
Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide
inferred← citeshttps://doi.org/10.1016/j.scib.2025.06.007openalex-snapshot
GABPα2β2 tetramer deficiency impairs natural killer cell maturation, compromising cytotoxicity and resistance against melanoma
inferred← citeshttps://doi.org/10.1016/j.tig.2024.11.008openalex-snapshot
Q-rich activation domains: flexible ‘rulers’ for transcription start site selection?
inferred← citeshttps://doi.org/10.1038/nri.2017.51openalex-snapshot
Transcriptional determination and functional specificity of myeloid cells: making sense of diversity
inferred← citeshttps://doi.org/10.1038/s41467-020-16209-5openalex-snapshot
Negative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression
inferred← citeshttps://doi.org/10.1038/s41467-020-18368-xopenalex-snapshot
Concerted localization-resets precede YAP-dependent transcription
inferred← citeshttps://doi.org/10.1038/s41467-023-39627-7openalex-snapshot
Single-cell profiling of lncRNA expression during Ebola virus infection in rhesus macaques
inferred← citeshttps://doi.org/10.1038/s41586-022-04877-wopenalex-snapshot
Compatibility rules of human enhancer and promoter sequences
inferred← citeshttps://doi.org/10.1038/s41590-020-0622-8openalex-snapshot
A molecular network regulating the proinflammatory phenotype of human memory T lymphocytes
inferred← citeshttps://doi.org/10.1038/s41590-021-00984-4openalex-snapshot
Human autoinflammatory disease reveals ELF4 as a transcriptional regulator of inflammation
inferred← citeshttps://doi.org/10.1038/s42003-021-02153-7openalex-snapshot
Transcription factor enrichment analysis (TFEA) quantifies the activity of multiple transcription factors from a single experiment
inferred← citeshttps://doi.org/10.1071/an20689openalex-snapshot
An integrated approach in gene-expression landscape profiling to identify housekeeping and tissue-specific genes in cattle
inferred← citeshttps://doi.org/10.1073/pnas.2502963122openalex-snapshot
Roles of transposable elements and DNA methylation in the formation of CpG islands and CpG-depleted regulatory elements
inferred← citeshttps://doi.org/10.1074/jbc.ra119.007866openalex-snapshot
Mechanism of cognate sequence discrimination by the ETS-family transcription factor ETS-1
inferred← citeshttps://doi.org/10.1080/21541264.2017.1378158openalex-snapshot
Housekeeping and tissue-specific cis-regulatory elements: Recipes for specificity and recipes for activity
inferred← citeshttps://doi.org/10.1089/scd.2021.0330openalex-snapshot
Using Live Imaging and Fluorescence Ubiquitinated Cell Cycle Indicator Embryonic Stem Cells to Distinguish G1 Cell Cycle Delays for General Stressors like Perfluoro-Octanoic Acid and Hyperosmotic Sorbitol or G2 Cell Cycle Delay for Mutagenic Stressors like Benzo(a)pyrene
inferred← citeshttps://doi.org/10.1093/nar/gkae088openalex-snapshot
Lineage-determining transcription factor-driven promoters regulate cell type-specific macrophage gene expression
inferred← citeshttps://doi.org/10.1093/nar/gkae706openalex-snapshot
Rapid profiling of transcription factor–cofactor interaction networks reveals principles of epigenetic regulation
inferred← citeshttps://doi.org/10.1093/nar/gkx821openalex-snapshot
Chromatin proteomics reveals novel combinatorial histone modification signatures that mark distinct subpopulations of macrophage enhancers
inferred← citeshttps://doi.org/10.1101/2020.12.04.411389openalex-snapshot
Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of the induction of IFN-mediated innate immune defences
inferred← citeshttps://doi.org/10.1101/2021.10.23.462170openalex-snapshot
Compatibility logic of human enhancer and promoter sequences
inferred← citeshttps://doi.org/10.1101/2022.07.18.500456openalex-snapshot
The logic of native enhancer-promoter compatibility and cell-type-specific gene expression variation
inferred← citeshttps://doi.org/10.1101/2023.08.30.555543openalex-snapshot
Architecture and evolutionary conservation of Xenopus tropicalis osteoblast-specific regulatory regions shed light on bone diseases and early skeletal evolution
inferred← citeshttps://doi.org/10.1101/2023.09.29.560106openalex-snapshot
Temperature elevation synergises with and enhances the type-I IFN-mediated restriction of MPXV
inferred← citeshttps://doi.org/10.1101/2024.04.26.590475openalex-snapshot
CRISPR PERSIST-On enables heritable and fine-tunable human gene activation
inferred← citeshttps://doi.org/10.1101/2024.09.13.612885openalex-snapshot
Novel regulator Fpr2 controls immune homeostasis via CCL4-dependent neutrophils
inferred← citeshttps://doi.org/10.1101/539049openalex-snapshot
Concerted localization-resets precede YAP-dependent transcription
inferred← citeshttps://doi.org/10.1101/gad.326348.119openalex-snapshot
Dissection of acute stimulus-inducible nucleosome remodeling in mammalian cells
inferred← citeshttps://doi.org/10.1101/gad.349282.121openalex-snapshot
H3K9 trimethylation in active chromatin restricts the usage of functional CTCF sites in SINE B2 repeats
inferred← citeshttps://doi.org/10.1101/gr.278130.123openalex-snapshot
Clustered and diverse transcription factor binding underlies cell type specificity of enhancers for housekeeping genes
inferred← citeshttps://doi.org/10.1186/s12864-024-10408-wopenalex-snapshot
Enhancer selectivity across cell types delineates three functionally distinct enhancer-promoter regulation patterns
inferred← citeshttps://doi.org/10.1186/s12915-024-01869-2openalex-snapshot
Integrative analysis of transcriptomic and epigenomic data reveals distinct patterns for developmental and housekeeping gene regulation
inferred← citeshttps://doi.org/10.1186/s13046-022-02505-zopenalex-snapshot
Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1
inferred← citeshttps://doi.org/10.1186/s13059-021-02322-1openalex-snapshot
Mechanisms of enhancer action: the known and the unknown
inferred← citeshttps://doi.org/10.1186/s13059-021-02485-xopenalex-snapshot
Mapping the evolving landscape of super-enhancers during cell differentiation
inferred← citeshttps://doi.org/10.1371/journal.pbio.3001065openalex-snapshot
Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defenses
inferred← citeshttps://doi.org/10.1371/journal.pgen.1007380openalex-snapshot
Sustained activation of detoxification pathways promotes liver carcinogenesis in response to chronic bile acid-mediated damage
inferred← citeshttps://doi.org/10.15252/embj.2019102161openalex-snapshot
FOXA2 controls the cis‐regulatory networks of pancreatic cancer cells in a differentiation grade‐specific manner
inferred← citeshttps://doi.org/10.3389/fendo.2023.1272646openalex-snapshot
Novel insights into the role of acetyl-CoA producing enzymes in epigenetic regulation
inferred← citeshttps://doi.org/10.4049/jimmunol.1701117openalex-snapshot
PARP14 Controls the Nuclear Accumulation of a Subset of Type I IFN–Inducible Proteins
inferred← citeshttps://doi.org/10.6084/m9.figshare.14429176openalex-snapshot
Additional file 1 of Mechanisms of enhancer action: the known and the unknown
inferred← citeshttps://doi.org/10.6084/m9.figshare.16625174openalex-snapshot
Additional file 1 of Mapping the evolving landscape of super-enhancers during cell differentiation
inferred← citeshttps://doi.org/10.6084/m9.figshare.16625177openalex-snapshot
Additional file 2 of Mapping the evolving landscape of super-enhancers during cell differentiation
inferred← citeshttps://doi.org/10.6084/m9.figshare.16625180openalex-snapshot
Additional file 3 of Mapping the evolving landscape of super-enhancers during cell differentiation
inferred← citeshttps://doi.org/10.6084/m9.figshare.16625183openalex-snapshot
Additional file 4 of Mapping the evolving landscape of super-enhancers during cell differentiation
inferred← citeshttps://doi.org/10.6084/m9.figshare.16625186openalex-snapshot
Additional file 5 of Mapping the evolving landscape of super-enhancers during cell differentiation
inferred← citeshttps://doi.org/10.6084/m9.figshare.16625189openalex-snapshot
Additional file 6 of Mapping the evolving landscape of super-enhancers during cell differentiation
inferred← citeshttps://doi.org/10.6084/m9.figshare.21301383openalex-snapshot
Additional file 10 of Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1
inferred← citeshttps://doi.org/10.6084/m9.figshare.21301386openalex-snapshot
Additional file 11 of Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1
inferred← citeshttps://doi.org/10.6084/m9.figshare.21301389openalex-snapshot
Additional file 12 of Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1
inferred← citeshttps://doi.org/10.6084/m9.figshare.21301392openalex-snapshot
Additional file 1 of Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1
inferred← citeshttps://doi.org/10.6084/m9.figshare.21301395openalex-snapshot
Additional file 2 of Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1
inferred← citeshttps://doi.org/10.6084/m9.figshare.21301398openalex-snapshot
Additional file 3 of Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1
inferred← citeshttps://doi.org/10.6084/m9.figshare.21301401openalex-snapshot
Additional file 4 of Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1
inferred← citeshttps://doi.org/10.6084/m9.figshare.21301404openalex-snapshot
Additional file 5 of Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1
inferred← citeshttps://doi.org/10.6084/m9.figshare.21301407openalex-snapshot
Additional file 6 of Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1
inferred← citeshttps://doi.org/10.6084/m9.figshare.21301410openalex-snapshot
Additional file 7 of Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1
inferred← citeshttps://doi.org/10.6084/m9.figshare.21301413openalex-snapshot
Additional file 8 of Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1
inferred← citeshttps://doi.org/10.6084/m9.figshare.21301416openalex-snapshot
Additional file 9 of Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1
inferred← citeshttps://doi.org/10.6084/m9.figshare.26721306openalex-snapshot
Additional file 1 of Enhancer selectivity across cell types delineates three functionally distinct enhancer-promoter regulation patterns
inferred← citeshttps://doi.org/10.6084/m9.figshare.26721309openalex-snapshot
Additional file 2 of Enhancer selectivity across cell types delineates three functionally distinct enhancer-promoter regulation patterns
inferred← citeshttps://doi.org/10.7554/elife.80943openalex-snapshot
Promoter sequence and architecture determine expression variability and confer robustness to genetic variants
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