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Functional divergence of diterpene syntheses in the medicinal plant Salvia miltiorrhiza Bunge

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/anie.201402911openalex-snapshot
Novel Product Chemistry from Mechanistic Analysis of ent ‐Copalyl Diphosphate Synthases from Plant Hormone Biosynthesis
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Bioactive tanshinones in Salvia miltiorrhiza inhibit the growth of prostate cancer cells in vitro and in mice
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AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
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Characterization of tanshinones in the roots of Salvia miltiorrhiza (Dan‐shen) by high‐performance liquid chromatography with electrospray ionization tandem mass spectrometry
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Isolation and characterization of a Ds-tagged rice (Oryza sativa L.) GA-responsive dwarf mutant defective in an early step of the gibberellin biosynthesis pathway
inferredcites →https://doi.org/10.1007/s10529-013-1358-4openalex-snapshot
RNA interference-mediated repression of SmCPS (copalyldiphosphate synthase) expression in hairy roots of Salvia miltiorrhiza causes a decrease of tanshinones and sheds light on the functional role of SmCPS
inferredcites →https://doi.org/10.1007/s11033-009-9703-3openalex-snapshot
Characterization of reference genes for quantitative real-time PCR analysis in various tissues of Salvia miltiorrhiza
inferredcites →https://doi.org/10.1007/s11240-006-9187-yopenalex-snapshot
Genetic transformation of the medicinal plant Salvia miltiorrhiza by Agrobacterium tumefaciens-mediated method
inferredcites →https://doi.org/10.1016/j.bbagen.2013.09.004openalex-snapshot
1.55Å-resolution structure of ent-copalyl diphosphate synthase and exploration of general acid function by site-directed mutagenesis
inferredcites →https://doi.org/10.1016/j.chroma.2009.04.017openalex-snapshot
Qualitative and quantitative analysis of diterpenoids in Salvia species by liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry
inferredcites →https://doi.org/10.1016/j.ejphar.2008.06.005openalex-snapshot
Tanshinone IIA: A new activator of human cardiac KCNQ1/KCNE1 (IKs) potassium channels
inferredcites →https://doi.org/10.1016/j.fct.2007.08.013openalex-snapshot
Cytotoxicity of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on HepG2 cells in relation to glutathione perturbation
inferredcites →https://doi.org/10.1016/j.phytochem.2014.01.021openalex-snapshot
Characterization of two genes for the biosynthesis of abietane-type diterpenes in rosemary (Rosmarinus officinalis) glandular trichomes
inferredcites →https://doi.org/10.1016/j.trsl.2007.11.005openalex-snapshot
Tanshinone IIA protects neonatal rat cardiomyocytes from adriamycin-induced apoptosis
inferredcites →https://doi.org/10.1016/j.ymeth.2010.01.005openalex-snapshot
A practical approach to RT-qPCR—Publishing data that conform to the MIQE guidelines
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A simple and rapid method for the differentiation of C-13 manoyl oxide epimers in biologically important samples using GC–MS analysis supported with NMR spectroscopy and computational chemistry results
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Structural Biology and Chemistry of the Terpenoid Cyclases
inferredcites →https://doi.org/10.1021/ja074977gopenalex-snapshot
A Single Residue Switch Converts Abietadiene Synthase into a Pimaradiene Specific Cyclase
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Toward a Biosynthetic Route to Sclareol and Amber Odorants
inferredcites →https://doi.org/10.1021/ja710524wopenalex-snapshot
Increasing Complexity of a Diterpene Synthase Reaction with a Single Residue Switch
inferredcites →https://doi.org/10.1021/jf901462sopenalex-snapshot
Chemical Characteristics of Salvia miltiorrhiza (Danshen) Collected from Different Locations in China
inferredcites →https://doi.org/10.1021/ol3026022openalex-snapshot
A Single Residue Change Leads to a Hydroxylated Product from the Class II Diterpene Cyclization Catalyzed by Abietadiene Synthase
inferredcites →https://doi.org/10.1021/ol902051vopenalex-snapshot
A Functional Genomics Approach to Tanshinone Biosynthesis Provides Stereochemical Insights
inferredcites →https://doi.org/10.1038/nchembio.578openalex-snapshot
Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase
inferredcites →https://doi.org/10.1073/pnas.0504284102openalex-snapshot
Formation of organelle-like N 2 -fixing symbiosomes in legume root nodules is controlled by DMI2
inferredcites →https://doi.org/10.1073/pnas.0611454104openalex-snapshot
Following evolution's lead to a single residue switch for diterpene synthase product outcome
inferredcites →https://doi.org/10.1073/pnas.0709466105openalex-snapshot
Functional plasticity of paralogous diterpene synthases involved in conifer defense
inferredcites →https://doi.org/10.1073/pnas.0712365105openalex-snapshot
Dissection of mechanisms of Chinese medicinal formula Realgar- Indigo naturalis as an effective treatment for promyelocytic leukemia
inferredcites →https://doi.org/10.1073/pnas.1218061110openalex-snapshot
CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts
inferredcites →https://doi.org/10.1074/jbc.m110.123307openalex-snapshot
A Single Residue Switch for Mg2+-dependent Inhibition Characterizes Plant Class II Diterpene Cyclases from Primary and Secondary Metabolism
inferredcites →https://doi.org/10.1093/bioinformatics/bti770openalex-snapshot
The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling
inferredcites →https://doi.org/10.1093/genetics/158.2.811openalex-snapshot
Genomic Organization of Plant Terpene Synthases and Molecular Evolutionary Implications
inferredcites →https://doi.org/10.1093/jxb/err466openalex-snapshot
Genome-wide identification and characterization of novel genes involved in terpenoid biosynthesis in Salvia miltiorrhiza
inferredcites →https://doi.org/10.1093/molbev/msh117openalex-snapshot
Frequent False Detection of Positive Selection by the Likelihood Method with Branch-Site Models
inferredcites →https://doi.org/10.1093/molbev/msi097openalex-snapshot
Bayes Empirical Bayes Inference of Amino Acid Sites Under Positive Selection
inferredcites →https://doi.org/10.1093/molbev/msi237openalex-snapshot
Evaluation of an Improved Branch-Site Likelihood Method for Detecting Positive Selection at the Molecular Level
inferredcites →https://doi.org/10.1093/molbev/msm088openalex-snapshot
PAML 4: Phylogenetic Analysis by Maximum Likelihood
inferredcites →https://doi.org/10.1093/molbev/msq303openalex-snapshot
Statistical Properties of the Branch-Site Test of Positive Selection
inferredcites →https://doi.org/10.1093/nar/gki198openalex-snapshot
MAFFT version 5: improvement in accuracy of multiple sequence alignment
inferredcites →https://doi.org/10.1093/sysbio/syq010openalex-snapshot
New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0
inferredcites →https://doi.org/10.1104/pp.104.050567openalex-snapshot
Rice Contains Two Disparate ent-Copalyl Diphosphate Synthases with Distinct Metabolic Functions
inferredcites →https://doi.org/10.1104/pp.106.095208openalex-snapshot
Synergistic Substrate Inhibition of ent-Copalyl Diphosphate Synthase: A Potential Feed-Forward Inhibition Mechanism Limiting Gibberellin Metabolism
inferredcites →https://doi.org/10.1104/pp.113.218347openalex-snapshot
Gene Discovery of Modular Diterpene Metabolism in Nonmodel Systems
inferredcites →https://doi.org/10.1104/pp.113.228429openalex-snapshot
Manoyl Oxide (13R), the Biosynthetic Precursor of Forskolin, Is Synthesized in Specialized Root Cork Cells in Coleus forskohlii
inferredcites →https://doi.org/10.1104/pp.113.231696openalex-snapshot
Evolution of Gene Structural Complexity: An Alternative-Splicing-Based Model Accounts for Intron-Containing Retrogenes
inferredcites →https://doi.org/10.1111/j.1365-313x.2011.04756.xopenalex-snapshot
Domain loss has independently occurred multiple times in plant terpene synthase evolution
inferredcites →https://doi.org/10.1111/j.1365-313x.2012.05068.xopenalex-snapshot
Characterization of two genes for the biosynthesis of the labdane diterpene Z ‐abienol in tobacco ( Nicotiana tabacum) glandular trichomes
inferredcites →https://doi.org/10.1111/j.1469-8137.2012.04212.xopenalex-snapshot
Highly conserved low‐copy nuclear genes as effective markers for phylogenetic analyses in angiosperms
inferredcites →https://doi.org/10.1146/annurev-arplant-050213-035705openalex-snapshot
To Gibberellins and Beyond! Surveying the Evolution of (Di)Terpenoid Metabolism
inferredcites →https://doi.org/10.1158/1535-7163.mct-07-0073openalex-snapshot
Phytochemistry and pharmacogenomics of natural products derived from traditional chinese medicine and chinese materia medica with activity against tumor cells
inferredcites →https://doi.org/10.1177/0091270005282630openalex-snapshot
Danshen: An Overview of Its Chemistry, Pharmacology, Pharmacokinetics, and Clinical Use
inferredcites →https://doi.org/10.1186/1471-2229-12-119openalex-snapshot
Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea(L.) and their relevance for perfume manufacture
inferredcites →https://doi.org/10.1248/yakushi1881.54.9_844openalex-snapshot
On the the Chemical Composition of Salvia Miltiorrhiza (Chinese drug Tan-Shen)
inferredcites →https://doi.org/10.1360/yc-007-1023openalex-snapshot
GSDS: a gene structure display server
inferredcites →https://doi.org/10.3390/molecules16032259openalex-snapshot
Diterpenoid Tanshinones and Phenolic Acids from Cultured Hairy Roots of Salvia miltiorrhiza Bunge and Their Antimicrobial Activities

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4753280openalex-extracted
Enhancing Secondary Metabolites and Stress Response in Salvia Miltiorrhiza Bunge Via Scwrky35 Overexpression: Insights from a Salvia Castanea Homolog
inferred← citeshttps://doi.org/10.2139/ssrn.4837258openalex-extracted
Genome-Wide Characterization and Expression of the Myb-Cc Gene Family in Salvia Miltiorrhiza Andsmmyb-Cc7-Mediated Response to Phosphate Starvation in Arabidopsis
inferred← citeshttps://doi.org/10.1002/med.21816openalex-snapshot
Recent progress and new perspectives for diterpenoid biosynthesis in medicinal plants
inferred← citeshttps://doi.org/10.1002/tpg2.20041openalex-snapshot
A high‐quality reference genome sequence of Salvia miltiorrhiza provides insights into tanshinone synthesis in its red rhizomes
inferred← citeshttps://doi.org/10.1007/978-3-030-24716-4_1openalex-snapshot
Salvia miltiorrhiza: An Economically and Academically Important Medicinal Plant
inferred← citeshttps://doi.org/10.1007/978-3-030-24716-4_10openalex-snapshot
Biosynthetic Pathway of Tanshinones in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.1007/978-3-030-24716-4_13openalex-snapshot
Genetic Transformation of Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.1007/978-3-030-24716-4_4openalex-snapshot
The Genome of Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.1007/978-3-319-73900-7_7openalex-snapshot
Biosynthesis of Salvia Specialized Metabolites and Biotechnological Approaches to Increase Their Production
inferred← citeshttps://doi.org/10.1007/978-981-10-1085-9_8openalex-snapshot
Salvia miltiorrhiza: A Medicinal Herb from Metabolites to Pathway Engineering
inferred← citeshttps://doi.org/10.1007/978-981-15-2874-3_2openalex-snapshot
Advanced Approaches for Biofortification
inferred← citeshttps://doi.org/10.1007/978-981-16-3529-8_12openalex-snapshot
Rhizobium rhizogenes-Mediated Genetic Transformation of Antidiabetic Plants
inferred← citeshttps://doi.org/10.1007/978-981-19-4771-1_3openalex-snapshot
TCM Related Multi-Omics Data Integration Techniques
inferred← citeshttps://doi.org/10.1007/s00299-018-2339-9openalex-snapshot
Overexpression of SmbHLH148 induced biosynthesis of tanshinones as well as phenolic acids in Salvia miltiorrhiza hairy roots
inferred← citeshttps://doi.org/10.1007/s00299-020-02562-8openalex-snapshot
smi-miR396b targeted SmGRFs, SmHDT1, and SmMYB37/4 synergistically regulates cell growth and active ingredient accumulation in Salvia miltiorrhiza hairy roots
inferred← citeshttps://doi.org/10.1007/s00299-025-03461-6openalex-snapshot
Genome-wide identification of the SmPHR gene family in Salvia miltiorrhiza and SmPHR7-mediated response to phosphate starvation in Arabidopsis thaliana
inferred← citeshttps://doi.org/10.1007/s00425-018-2884-zopenalex-snapshot
The ethylene response factor SmERF6 co-regulates the transcription of SmCPS1 and SmKSL1 and is involved in tanshinone biosynthesis in Salvia miltiorrhiza hairy roots
inferred← citeshttps://doi.org/10.1007/s00709-016-1045-0openalex-snapshot
Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.1007/s10528-024-10964-6openalex-snapshot
Quantitative Trait Locus Mapping and Candidate Gene Analysis of the Contents of Three Tanshinone Components in Salvia miltiorrhiza Bunge
inferred← citeshttps://doi.org/10.1007/s10529-016-2098-zopenalex-snapshot
Characterization of a monoterpene synthase from Paeonia lactiflora producing α-pinene as its single product
inferred← citeshttps://doi.org/10.1007/s11101-018-9550-8openalex-snapshot
NMR spectroscopy and mass spectrometry in metabolomics analysis of Salvia
inferred← citeshttps://doi.org/10.1007/s11103-019-00845-7openalex-snapshot
The AP2/ERF transcription factor SmERF128 positively regulates diterpenoid biosynthesis in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.1007/s11240-018-1405-xopenalex-snapshot
Phenolic acid production is more effectively enhanced than tanshinone production by methyl jasmonate in Salvia miltiorrhiza hairy roots
inferred← citeshttps://doi.org/10.1007/s11427-018-9352-7openalex-snapshot
Trends in herbgenomics
inferred← citeshttps://doi.org/10.1007/s11427-018-9472-yopenalex-snapshot
Herbgenomics: A stepping stone for research into herbal medicine
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Recent advances in biosynthesis of bioactive compounds in traditional Chinese medicinal plants
inferred← citeshttps://doi.org/10.1007/s11738-017-2563-xopenalex-snapshot
Coding single nucleotide polymorphisms and SmCPS1 and SmKSL1 subcellular localization are associated with tanshinone biosynthesis in Salvia miltiorrhiza Bunge roots
inferred← citeshttps://doi.org/10.1007/s11738-020-03119-8openalex-snapshot
Physiological responses of white mustard grown in Zn-contaminated soils
inferred← citeshttps://doi.org/10.1007/s12539-019-00342-xopenalex-snapshot
Computer-Aided Saturation Mutagenesis of Arabidopsis thaliana Ent-Copalyl Diphosphate Synthase
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Advances in hairy root technology: from pathway elucidation and omics integration for the scale-up production of biomolecules
inferred← citeshttps://doi.org/10.1016/b978-0-443-18925-8.00013-1openalex-snapshot
Hairy root culture: a reliable bioreactor from transgenic plants
inferred← citeshttps://doi.org/10.1016/j.apsb.2021.04.008openalex-snapshot
Functional identification of the terpene synthase family involved in diterpenoid alkaloids biosynthesis in Aconitum carmichaelii
inferred← citeshttps://doi.org/10.1016/j.apsb.2022.02.013openalex-snapshot
Mechanistic analysis for the origin of diverse diterpenes in Tripterygium wilfordii
inferred← citeshttps://doi.org/10.1016/j.apsb.2025.12.018openalex-snapshot
The transcriptional regulatory network involved in periderm-specific tanshinones biosynthesis in Salvia miltiorrhiza root
inferred← citeshttps://doi.org/10.1016/j.bbrc.2016.06.036openalex-snapshot
RNA interference targeting CYP76AH1 in hairy roots of Salvia miltiorrhiza reveals its key role in the biosynthetic pathway of tanshinones
inferred← citeshttps://doi.org/10.1016/j.bbrc.2019.03.057openalex-snapshot
An alternative splicing alters the product outcome of a class I terpene synthase in Isodon rubescens
inferred← citeshttps://doi.org/10.1016/j.bej.2017.12.007openalex-snapshot
Diverse specialized metabolism and their responses to lactalbumin hydrolysate in hairy root cultures of Salvia miltiorrhiza Bunge and Salvia castanea Diels f. t omentosa Stib
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.111236openalex-snapshot
The sage genome provides insight into the evolutionary dynamics of diterpene biosynthesis gene cluster in plants
inferred← citeshttps://doi.org/10.1016/j.gene.2017.11.067openalex-snapshot
Diverse responses of tanshinone biosynthesis to biotic and abiotic elicitors in hairy root cultures of Salvia miltiorrhiza and Salvia castanea Diels f . tomentosa
inferred← citeshttps://doi.org/10.1016/j.gene.2023.148094openalex-snapshot
Endophytic fungus Penicillium steckii DF33 promoted tanshinones biosynthesis in Salvia miltiorrhiza by regulating the expression of CYP450 genes
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.143688openalex-snapshot
The APETALA2/ETHYLENE RESPONSE FACTOR transcription factor SmERF005 negatively regulates meristem cell division and biosynthesis of phenolic acids and diterpenoids in Salvia miltiorrhiza hairy roots
inferred← citeshttps://doi.org/10.1016/j.indcrop.2019.01.001openalex-snapshot
Expression patterns of some genes involved in tanshinone biosynthesis in Salvia miltiorrhiza roots
inferred← citeshttps://doi.org/10.1016/j.indcrop.2019.112004openalex-snapshot
SmGRAS3 negatively responds to GA signaling while promotes tanshinones biosynthesis in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.1016/j.indcrop.2021.113784openalex-snapshot
Integrative analysis of metabolome and transcriptome reveals the mechanism of color formation in white root (Salvia miltiorrhiza)
inferred← citeshttps://doi.org/10.1016/j.indcrop.2024.119056openalex-snapshot
The SmWRKY32-SmERF128 module regulates tanshinone biosynthesis in Salvia miltiorrhiza hairy roots
inferred← citeshttps://doi.org/10.1016/j.indcrop.2025.121999openalex-snapshot
Targeted knockout of SmCPS4 elevates tanshinone production in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.1016/j.molp.2016.03.010openalex-snapshot
Analysis of the Genome Sequence of the Medicinal Plant Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.1016/j.molp.2022.09.007openalex-snapshot
Metabolomics-centered mining of plant metabolic diversity and function: Past decade and future perspectives
inferred← citeshttps://doi.org/10.1016/j.molp.2023.01.006openalex-snapshot
The genomes of medicinal skullcaps reveal the polyphyletic origins of clerodane diterpene biosynthesis in the family Lamiaceae
inferred← citeshttps://doi.org/10.1016/j.pbi.2020.03.005openalex-snapshot
Gene and genome duplications in the evolution of chemodiversity: perspectives from studies of Lamiaceae
inferred← citeshttps://doi.org/10.1016/j.pbi.2022.102189openalex-snapshot
Tanshinones: Leading the way into Lamiaceae labdane-related diterpenoid biosynthesis
inferred← citeshttps://doi.org/10.1016/j.phytochem.2018.11.015openalex-snapshot
Diterpene synthases facilitating production of the kaurane skeleton of eriocalyxin B in the medicinal plant Isodon eriocalyx
inferred← citeshttps://doi.org/10.1016/j.phytochem.2019.112183openalex-snapshot
SmbHLH3 acts as a transcription repressor for both phenolic acids and tanshinone biosynthesis in Salvia miltiorrhiza hairy roots
inferred← citeshttps://doi.org/10.1016/j.plantsci.2018.07.016openalex-snapshot
Overexpression of SmbHLH10 enhances tanshinones biosynthesis in Salvia miltiorrhiza hairy roots
inferred← citeshttps://doi.org/10.1016/j.plantsci.2024.112046openalex-snapshot
ApCPS2 contributes to medicinal diterpenoid biosynthesis and defense against insect herbivore in Andrographis paniculata
inferred← citeshttps://doi.org/10.1016/j.plantsci.2024.112080openalex-snapshot
Functional identification of specialized diterpene synthases from Chamaecyparis obtusa and C. obtusa var. formosana to illustrate the putative evolution of diterpene synthases in Cupressaceae
inferred← citeshttps://doi.org/10.1016/j.plantsci.2025.112384openalex-snapshot
New insights of advanced biotechnological engineering strategies for tanshinone biosynthesis in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.1016/j.plantsci.2025.112440openalex-snapshot
SmGRAS5 acts as a positive regulator in GA-induced biosynthesis of tanshinones in Salvia miltiorrhiza hairy roots
inferred← citeshttps://doi.org/10.1016/j.plantsci.2026.112981openalex-snapshot
Functional characterization of the key enzyme gene SmAOC1/2 in Salvia miltiorrhiza Bunge jasmonic acid biosynthesis pathway
inferred← citeshttps://doi.org/10.1016/j.plaphy.2016.03.003openalex-snapshot
Arabidopsis DREB1B in transgenic Salvia miltiorrhiza increased tolerance to drought stress without stunting growth
inferred← citeshttps://doi.org/10.1016/j.plaphy.2023.107968openalex-snapshot
Functional diversity of diterpene synthases in Aconitum plants
inferred← citeshttps://doi.org/10.1016/j.plaphy.2024.108671openalex-snapshot
Changes in secondary metabolites contents and stress responses in Salvia miltiorrhiza via ScWRKY35 overexpression: Insights from a wild relative Salvia castanea
inferred← citeshttps://doi.org/10.1016/j.plaphy.2024.108932openalex-snapshot
The methyl jasmonate-responsive transcription factor SmERF106 promotes tanshinone accumulation in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.1016/j.plaphy.2024.109190openalex-snapshot
Identification and functional characterization of the diterpene synthase family in Pogostemon cablin (Blanco) Benth
inferred← citeshttps://doi.org/10.1016/j.plaphy.2025.109677openalex-snapshot
Functional identification of the diterpene synthases exploring the landscape of diterpene structural diversity in Isodon
inferred← citeshttps://doi.org/10.1016/j.tibtech.2020.06.012openalex-snapshot
Biotechnological Exploration of Transformed Root Culture for Value-Added Products
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Mining plant metabolomes: Methods, applications, and perspectives
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Extreme promiscuity of a bacterial and a plant diterpene synthase enables combinatorial biosynthesis
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Combinatorial biosynthesis and the basis for substrate promiscuity in class I diterpene synthases
inferred← citeshttps://doi.org/10.1016/j.ymben.2020.08.002openalex-snapshot
Production of multiple terpenes of different chain lengths by subcellular targeting of multi-substrate terpene synthase in plants
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Metabolic engineering of artificially modified transcription factor SmMYB36-VP16 for high-level production of tanshinones and phenolic acids
inferred← citeshttps://doi.org/10.1016/s1674-6384(16)60001-1openalex-snapshot
Medicinal Model Plants: Breaking the Traditional Medicine Research Methods
inferred← citeshttps://doi.org/10.1016/s1674-6384(16)60002-3openalex-snapshot
Biosynthesis and Regulation of Active Compounds in Medicinal Model Plant Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.1016/s1875-5364(16)30097-8openalex-snapshot
The phenylalanine ammonia-lyase gene family in Isatis indigotica Fort.: molecular cloning, characterization, and expression analysis
inferred← citeshttps://doi.org/10.1016/s1875-5364(21)60100-0openalex-snapshot
A review: biosynthesis of plant-derived labdane-related diterpenoids
inferred← citeshttps://doi.org/10.1021/acs.biochem.8b00193openalex-snapshot
Catalytic Bases and Stereocontrol in Lamiaceae Class II Diterpene Cyclases
inferred← citeshttps://doi.org/10.1021/acs.jafc.5b04697openalex-snapshot
Enhanced Diterpene Tanshinone Accumulation and Bioactivity of Transgenic Salvia miltiorrhiza Hairy Roots by Pathway Engineering
inferred← citeshttps://doi.org/10.1021/acscatal.3c05918openalex-snapshot
From Functional Plasticity of Two Diterpene Synthases (IrTPS2/IrKSL3a) to Enzyme Evolution
inferred← citeshttps://doi.org/10.1038/s41467-021-20959-1openalex-snapshot
Expansion within the CYP71D subfamily drives the heterocyclization of tanshinones synthesis in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.1038/s41467-023-35845-1openalex-snapshot
Uncovering a miltiradiene biosynthetic gene cluster in the Lamiaceae reveals a dynamic evolutionary trajectory
inferred← citeshttps://doi.org/10.1038/s41467-023-40401-yopenalex-snapshot
Functional divergence of CYP76AKs shapes the chemodiversity of abietane-type diterpenoids in genus Salvia
inferred← citeshttps://doi.org/10.1038/s41598-018-25315-wopenalex-snapshot
Systematic analysis of DEMETER-like DNA glycosylase genes shows lineage-specific Smi-miR7972 involved in SmDML1 regulation in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.1038/s41598-019-42164-3openalex-snapshot
Proteomic analysis reveals novel insights into tanshinones biosynthesis in Salvia miltiorrhiza hairy roots
inferred← citeshttps://doi.org/10.1038/s41598-019-51535-9openalex-snapshot
Transcriptomic analysis reveals potential genes involved in tanshinone biosynthesis in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.1038/s41598-024-53510-5openalex-snapshot
Comparative transcriptomics of two Salvia subg. Perovskia species contribute towards molecular background of abietane-type diterpenoid biosynthesis
inferred← citeshttps://doi.org/10.1038/srep23057openalex-snapshot
Functional characterization of ent-copalyl diphosphate synthase, kaurene synthase and kaurene oxidase in the Salvia miltiorrhiza gibberellin biosynthetic pathway
inferred← citeshttps://doi.org/10.1038/srep43320openalex-snapshot
Targeted mutagenesis in the medicinal plant Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.1042/bcj20190479openalex-snapshot
Conserved bases for the initial cyclase in gibberellin biosynthesis: from bacteria to plants
inferred← citeshttps://doi.org/10.1074/jbc.ra118.006025openalex-snapshot
A database-driven approach identifies additional diterpene synthase activities in the mint family (Lamiaceae)
inferred← citeshttps://doi.org/10.1080/07352689.2021.1935719openalex-snapshot
Biosynthesis and Regulatory Mechanisms of Bioactive Compounds in Salvia miltiorrhiza, a Model System for Medicinal Plant Biology
inferred← citeshttps://doi.org/10.1080/13880209.2019.1680706openalex-snapshot
Transcriptome sequencing of Salvia miltiorrhiza after infection by its endophytic fungi and identification of genes related to tanshinone biosynthesis
inferred← citeshttps://doi.org/10.1093/hr/uhac238openalex-snapshot
The SmMYB36-SmERF6/SmERF115 module regulates the biosynthesis of tanshinones and phenolic acids in salvia miltiorrhiza hairy roots
inferred← citeshttps://doi.org/10.1093/hr/uhad069openalex-snapshot
Chromosome-level genome assembly of Salvia miltiorrhiza with orange roots uncovers the role of Sm2OGD3 in catalyzing 15,16-dehydrogenation of tanshinones
inferred← citeshttps://doi.org/10.1093/hr/uhad114openalex-snapshot
Characteristics ofSalvia miltiorrhizamethylome and the regulatory mechanism of DNA methylation in tanshinone biosynthesis
inferred← citeshttps://doi.org/10.1093/hr/uhaf058openalex-snapshot
Molecular mechanism of SmMYB53 activates the expression of SmCYP71D375, thereby modulating tanshinone accumulation in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.1093/jxb/erw493openalex-snapshot
A (–)-kolavenyl diphosphate synthase catalyzes the first step of salvinorin A biosynthesis in Salvia divinorum
inferred← citeshttps://doi.org/10.1093/jxb/erx113openalex-snapshot
The 2-oxoglutarate-dependent dioxygenase superfamily participates in tanshinone production in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.1093/jxb/erx484openalex-snapshot
SmJAZ8 acts as a core repressor regulating JA-induced biosynthesis of salvianolic acids and tanshinones in Salvia miltiorrhiza hairy roots
inferred← citeshttps://doi.org/10.1093/jxb/ery349openalex-snapshot
The biosynthesis of phenolic acids is positively regulated by the JA-responsive transcription factor ERF115 inSalvia miltiorrhiza
inferred← citeshttps://doi.org/10.1093/pcp/pcab089openalex-snapshot
Discovery and Functional Characterization of a Diverse Diterpene Synthase Family in the Medicinal Herb Isodon lophanthoides Var. gerardiana
inferred← citeshttps://doi.org/10.1104/pp.15.01353openalex-snapshot
Comparative transcriptomics unravel biochemical specialization of leaf tissues of Stevia (Stevia rebaudiana) for diterpenoid production
inferred← citeshttps://doi.org/10.1104/pp.17.00202openalex-snapshot
Functional Diversification of Kaurene Synthase-Like Genes in Isodon rubescens
inferred← citeshttps://doi.org/10.1104/pp.17.01351openalex-snapshot
Discovery, Biosynthesis and Stress-Related Accumulation of Dolabradiene-Derived Defenses in Maize
inferred← citeshttps://doi.org/10.1104/pp.18.00590openalex-snapshot
Functional Diversity of Diterpene Synthases in the Biofuel Crop Switchgrass
inferred← citeshttps://doi.org/10.1111/jipb.13806openalex-snapshot
The ABC transporter SmABCG1 mediates tanshinones export from the peridermic cells of Salvia miltiorrhiza root
inferred← citeshttps://doi.org/10.1111/nph.13790openalex-snapshot
Cytochrome P450 promiscuity leads to a bifurcating biosynthetic pathway for tanshinones
inferred← citeshttps://doi.org/10.1111/nph.17463openalex-snapshot
The ERF‐VII transcription factor SmERF73 coordinately regulates tanshinone biosynthesis in response to stress elicitors in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.1111/pbi.13933openalex-snapshot
Structural and mechanistic insights into the precise product synthesis by a bifunctional miltiradiene synthase
inferred← citeshttps://doi.org/10.1111/tpj.13427openalex-snapshot
Biosynthesis of the psychotropic plant diterpene salvinorin A: Discovery and characterization of the Salvia divinorum clerodienyl diphosphate synthase
inferred← citeshttps://doi.org/10.1186/s12864-025-11535-8openalex-snapshot
Genome-wide characterization and expression analysis of WRKY family genes in the biosynthesis of triptolide in Tripterygium wilfordii
inferred← citeshttps://doi.org/10.1186/s12870-018-1505-0openalex-snapshot
Comparative transcriptome analysis of roots, stems and leaves of Isodon amethystoides reveals candidate genes involved in Wangzaozins biosynthesis
inferred← citeshttps://doi.org/10.1186/s13007-019-0439-3openalex-snapshot
Enhancement of tanshinone production in Salvia miltiorrhiza hairy root cultures by metabolic engineering
inferred← citeshttps://doi.org/10.1186/s13020-019-0265-6openalex-snapshot
Metabolome and transcriptome analyses reveal quality change in the orange-rooted Salvia miltiorrhiza (Danshen) from cultivated field
inferred← citeshttps://doi.org/10.1186/s13020-024-00971-5openalex-snapshot
Biosynthesis and signal transduction of plant growth regulators and their effects on bioactive compound production in Salvia miltiorrhiza (Danshen)
inferred← citeshttps://doi.org/10.1242/bio.017178openalex-snapshot
Genome-wide analysis of auxin response factor gene family members in medicinal model plantSalvia miltiorrhiza
inferred← citeshttps://doi.org/10.1371/journal.pone.0176507openalex-snapshot
Biosynthesis of the oxygenated diterpene nezukol in the medicinal plant Isodon rubescens is catalyzed by a pair of diterpene synthases
inferred← citeshttps://doi.org/10.1371/journal.pone.0207097openalex-snapshot
Genome-wide detection of terpene synthase genes in holy basil (Ocimum sanctum L.)
inferred← citeshttps://doi.org/10.17221/97/2017-cjgpbopenalex-snapshot
Correlations between SmCPS1 promoter polymorphism and tanshinone contents in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.21203/rs.3.rs-1535494/v1openalex-snapshot
Uncovering a miltiradiene biosynthetic gene cluster in the Lamiaceae reveals a dynamic evolutionary trajectory
inferred← citeshttps://doi.org/10.3389/fgene.2021.645115openalex-snapshot
Genome-Wide Identification of Circular RNAs Potentially Involved in the Biosynthesis of Secondary Metabolites in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.3389/fphar.2019.00202openalex-snapshot
Tanshinones, Critical Pharmacological Components in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.3389/fpls.2017.00052openalex-snapshot
Modulating AtDREB1C Expression Improves Drought Tolerance in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.3389/fpls.2017.00627openalex-snapshot
Identification of a Novel (-)-5-Epieremophilene Synthase from Salvia miltiorrhiza via Transcriptome Mining
inferred← citeshttps://doi.org/10.3389/fpls.2018.01542openalex-snapshot
Functional Characterization of Two Class II Diterpene Synthases Indicates Additional Specialized Diterpenoid Pathways in Maize (Zea mays)
inferred← citeshttps://doi.org/10.3389/fpls.2019.01166openalex-snapshot
Terpene Synthases as Metabolic Gatekeepers in the Evolution of Plant Terpenoid Chemical Diversity
inferred← citeshttps://doi.org/10.3389/fpls.2019.01367openalex-snapshot
SmGRAS1 and SmGRAS2 Regulate the Biosynthesis of Tanshinones and Phenolic Acids in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.3389/fpls.2020.559438openalex-snapshot
SmMYC2b Enhances Tanshinone Accumulation in Salvia miltiorrhiza by Activating Pathway Genes and Promoting Lateral Root Development
inferred← citeshttps://doi.org/10.3389/fpls.2021.667678openalex-snapshot
Chia (Salvia hispanica) Gene Expression Atlas Elucidates Dynamic Spatio-Temporal Changes Associated With Plant Growth and Development
inferred← citeshttps://doi.org/10.3389/fpls.2024.1279738openalex-snapshot
Enhancement of specialized metabolites using CRISPR/Cas gene editing technology in medicinal plants
inferred← citeshttps://doi.org/10.3389/fpls.2024.1463666openalex-snapshot
Application of metabolomics in quality control of traditional Chinese medicines: a review
inferred← citeshttps://doi.org/10.3389/fpls.2026.1943006openalex-snapshot
Functional identification of two cytochrome P450 enzymes involved in diterpenoid oxidation in Ginkgo biloba
inferred← citeshttps://doi.org/10.3390/biom13121725openalex-snapshot
Functions of Representative Terpenoids and Their Biosynthesis Mechanisms in Medicinal Plants
inferred← citeshttps://doi.org/10.3390/biom14010120openalex-snapshot
Sequence-Structure Analysis Unlocking the Potential Functional Application of the Local 3D Motifs of Plant-Derived Diterpene Synthases
inferred← citeshttps://doi.org/10.3390/genes14010054openalex-snapshot
Isolation of Salvia miltiorrhiza Kaurene Synthase-like (KSL) Gene Promoter and Its Regulation by Ethephon and Yeast Extract
inferred← citeshttps://doi.org/10.3390/ijms21093101openalex-snapshot
Integrated Analysis of mRNA and microRNA Elucidates the Regulation of Glycyrrhizic Acid Biosynthesis in Glycyrrhiza uralensis Fisch
inferred← citeshttps://doi.org/10.3390/molecules200916235openalex-snapshot
The Biosynthetic Pathways of Tanshinones and Phenolic Acids in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.3390/molecules23112952openalex-snapshot
Transcriptomic Insight into Terpenoid Biosynthesis and Functional Characterization of Three Diterpene Synthases in Scutellaria barbata
inferred← citeshttps://doi.org/10.3390/molecules29174016openalex-snapshot
UHPLC-QTOF-MS-Based Targeted Metabolomics Provides Novel Insights into the Accumulative Mechanism of Soil Types on the Bioactive Components of Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.3390/plants12010069openalex-snapshot
Functional Characterization of Three Diterpene Synthases Responsible for Tetracyclic Diterpene Biosynthesis in Scoparia dulcis
inferred← citeshttps://doi.org/10.3390/plants12193385openalex-snapshot
Salvia officinalis L. and Salvia sclarea Essential Oils: Chemical Composition, Biological Activities and Preservative Effects against Listeria monocytogenes Inoculated into Minced Beef Meat
inferred← citeshttps://doi.org/10.3835/plantgenome2015.08.0077openalex-snapshot
Genome‐Wide Identification of the AP2/ERF Gene Family Involved in Active Constituent Biosynthesis in Salvia miltiorrhiza
inferred← citeshttps://doi.org/10.70675/5e45bb7az93d3z4c80zbc60zed1b729bd936openalex-snapshot
Biosynthèse et rôle biologique des diterpènes dans les graines de caféiers
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