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Sleep quality and quantity determined by polysomnography in mechanically ventilated critically ill patients randomized to dexmedetomidine or placebo

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/jama.2009.56openalex-snapshot
Dexmedetomidine vs Midazolam for Sedation of Critically Ill Patients A Randomized Trial
inferredcites →https://doi.org/10.1001/jama.2012.304openalex-snapshot
Dexmedetomidine vs Midazolam or Propofol for Sedation During Prolonged Mechanical Ventilation
inferredcites →https://doi.org/10.1001/jama.289.22.2983openalex-snapshot
Monitoring Sedation Status Over Time in ICU Patients
inferredcites →https://doi.org/10.1001/jama.291.14.1753openalex-snapshot
Delirium as a Predictor of Mortality in Mechanically Ventilated Patients in the Intensive Care Unit
inferredcites →https://doi.org/10.1001/jama.298.22.2644openalex-snapshot
Effect of Sedation With Dexmedetomidine vs Lorazepam on Acute Brain Dysfunction in Mechanically Ventilated Patients
inferredcites →https://doi.org/10.1007/s00134-003-2030-6openalex-snapshot
Sleep in the intensive care unit
inferredcites →https://doi.org/10.1007/s00134-009-1397-4openalex-snapshot
Sleep and delirium in ICU patients: a review of mechanisms and manifestations
inferredcites →https://doi.org/10.1007/s00134-012-2623-zopenalex-snapshot
Effects of propofol on sleep quality in mechanically ventilated critically ill patients: a physiological study
inferredcites →https://doi.org/10.1007/s00134-012-2685-yopenalex-snapshot
Sleep quality of mechanically ventilated patients sedated with dexmedetomidine
inferredcites →https://doi.org/10.1007/s00134-016-4297-4openalex-snapshot
Comfort and patient-centred care without excessive sedation: the eCASH concept
inferredcites →https://doi.org/10.1007/s12028-011-9520-0openalex-snapshot
Delirium and Sedation in the ICU
inferredcites →https://doi.org/10.1007/s40262-017-0507-7openalex-snapshot
Clinical Pharmacokinetics and Pharmacodynamics of Dexmedetomidine
inferredcites →https://doi.org/10.1016/j.anclin.2011.09.007openalex-snapshot
Sedation and Sleep Disturbances in the ICU
inferredcites →https://doi.org/10.1016/j.clinph.2017.10.005openalex-snapshot
Dexmedetomidine promotes biomimetic non-rapid eye movement stage 3 sleep in humans: A pilot study
inferredcites →https://doi.org/10.1016/j.jcrc.2016.09.005openalex-snapshot
Sleep in intensive care unit: The role of environment
inferredcites →https://doi.org/10.1016/j.jcrc.2016.12.006openalex-snapshot
Circadian disruption of ICU patients: A review of pathways, expression, and interventions
inferredcites →https://doi.org/10.1016/j.sleep.2011.07.012openalex-snapshot
A new classification for sleep analysis in critically ill patients
inferredcites →https://doi.org/10.1053/j.jvca.2014.03.010openalex-snapshot
Dexmedetomidine Reduces the Risk of Delirium, Agitation and Confusion in Critically Ill Patients: A Meta-analysis of Randomized Controlled Trials
inferredcites →https://doi.org/10.1055/s-2007-998867openalex-snapshot
Alpha2-Agonisten in Anästhesie und Intensivmedizin
inferredcites →https://doi.org/10.1056/nejmc2011055openalex-snapshot
Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients
inferredcites →https://doi.org/10.1056/nejmoa1906759openalex-snapshot
Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients
inferredcites →https://doi.org/10.1097/00000539-200003000-00035openalex-snapshot
Sedative, Amnestic, and Analgesic Properties of Small-Dose Dexmedetomidine Infusions
inferredcites →https://doi.org/10.1097/00000542-200302000-00024openalex-snapshot
The α2-Adrenoceptor Agonist Dexmedetomidine Converges on an Endogenous Sleep-promoting Pathway to Exert Its Sedative Effects
inferredcites →https://doi.org/10.1097/00000542-200601000-00005openalex-snapshot
Lorazepam Is an Independent Risk Factor for Transitioning to Delirium in Intensive Care Unit Patients
inferredcites →https://doi.org/10.1097/00003246-199701000-00009openalex-snapshot
Prolonged sedation of critically ill patients with midazolam or propofol
inferredcites →https://doi.org/10.1097/aln.0000000000000361openalex-snapshot
Effects of Dexmedetomidine on Sleep Quality in Critically Ill Patients
inferredcites →https://doi.org/10.1097/ccm.0b013e3181643f29openalex-snapshot
Sleep and recovery from critical illness and injury: A review of theory, current practice, and future directions*
inferredcites →https://doi.org/10.1097/ccm.0b013e3181a5689fopenalex-snapshot
Randomized trial of light versus deep sedation on mental health after critical illness*
inferredcites →https://doi.org/10.1097/ccm.0b013e3181f85759openalex-snapshot
Delirium duration and mortality in lightly sedated, mechanically ventilated intensive care patients*
inferredcites →https://doi.org/10.1097/ccm.0b013e3182783b72openalex-snapshot
Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit
inferredcites →https://doi.org/10.1097/ccm.0b013e31828a3f75openalex-snapshot
Atypical Sleep in Ventilated Patients
inferredcites →https://doi.org/10.1111/aas.14154openalex-snapshot
Sleep quality and quantity determined by polysomnography in mechanically ventilated critically ill patients randomized to dexmedetomidine or placebo
inferredcites →https://doi.org/10.1136/bmjopen-2021-050282openalex-snapshot
Dexmedetomidine and sleep quality in mechanically ventilated critically ill patients: study protocol for a randomised placebo-controlled trial
inferredcites →https://doi.org/10.1164/ajrccm.163.2.9912128openalex-snapshot
Abnormal Sleep/Wake Cycles and the Effect of Environmental Noise on Sleep Disruption in the Intensive Care Unit
inferredcites →https://doi.org/10.1164/rccm.201310-1815ocopenalex-snapshot
Rapidly Reversible, Sedation-related Delirium versus Persistent Delirium in the Intensive Care Unit
inferredcites →https://doi.org/10.1164/rccm.201504-0767stopenalex-snapshot
An Official American Thoracic Society Statement: The Importance of Healthy Sleep. Recommendations and Future Priorities
inferredcites →https://doi.org/10.1164/rccm.201710-1995ocopenalex-snapshot
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial
inferredcites →https://doi.org/10.1164/rccm.2107138openalex-snapshot
The Richmond Agitation–Sedation Scale: Validity and Reliability in Adult Intensive Care Unit Patients
inferredcites →https://doi.org/10.1186/1745-6215-15-499openalex-snapshot
Non-sedation versus sedation with a daily wake-up trial in critically ill patients receiving mechanical ventilation (NONSEDA Trial): study protocol for a randomised controlled trial
inferredcites →https://doi.org/10.1186/cc10042openalex-snapshot
How did you sleep in the ICU?
inferredcites →https://doi.org/10.1186/s13613-021-00829-1openalex-snapshot
Serum melatonin concentration in critically ill patients randomized to sedation or non-sedation
inferredcites →https://doi.org/10.1371/journal.pone.0082913openalex-snapshot
Dexmedetomidine as a Sedative Agent in Critically Ill Patients: A Meta-Analysis of Randomized Controlled Trials
inferredcites →https://doi.org/10.1378/chest.117.3.809openalex-snapshot
Sleep in Critically Ill Patients Requiring Mechanical Ventilation
inferredcites →https://doi.org/10.1513/annalsats.201702-148sropenalex-snapshot
Sleep Disturbance after Hospitalization and Critical Illness: A Systematic Review
inferredcites →https://doi.org/10.2147/nss.s151525openalex-snapshot
Sleep quality and circadian rhythm disruption in the intensive care unit: a review
inferredcites →https://doi.org/10.3402/jchimp.v4.24983openalex-snapshot
How to interpret the results of a sleep study
inferredcites →https://doi.org/10.4037/ajcc2021221openalex-snapshot
Daytime-to-Nighttime Sleep Ratios and Cognitive Impairment in Older Intensive Care Unit Survivors
inferredcites →https://doi.org/10.5664/jcsm.6576openalex-snapshot
AASM Scoring Manual Updates for 2017 (Version 2.4)

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4690504openalex-extracted
Effect of Procedural Sedation on Sleep Quality of Pediatric Outpatients: A Single-Centre, Self-Controlled, Observational Study
inferred← citeshttps://doi.org/10.1002/jcph.6151openalex-snapshot
Pharmacological Management of Sleep–Wake Disturbances in Delirium
inferred← citeshttps://doi.org/10.1016/j.bja.2023.11.014openalex-snapshot
Effect of prolonged sedation with dexmedetomidine, midazolam, propofol, and sevoflurane on sleep homeostasis in rats
inferred← citeshttps://doi.org/10.1016/j.brainres.2025.149482openalex-snapshot
Role of dexmedetomidine in postoperative cognitive dysfunction and sleep improvement in aged rats by regulating the PI3K/Akt signaling pathway and its mechanism
inferred← citeshttps://doi.org/10.1016/j.ccrj.2024.06.009openalex-snapshot
A multicentre point prevalence study of nocturnal hours awake and enteral pharmacological sleep aids in patients admitted to Australian and New Zealand intensive care units
inferred← citeshttps://doi.org/10.1016/j.ccrj.2026.100181openalex-snapshot
Interpreting sleep outcomes in the ICU: Reflections on the DREAM trial—Author’s reply
inferred← citeshttps://doi.org/10.1016/j.jaclp.2026.02.002openalex-snapshot
Circadian Dysfunction in Delirium: A Systematic Review
inferred← citeshttps://doi.org/10.1016/j.redar.2025.501805openalex-snapshot
Guía clínica y plan estratégico para la prevención, el diagnóstico y el tratamiento del delirium: Proyecto Delirium Zero
inferred← citeshttps://doi.org/10.1016/j.redare.2025.501805openalex-snapshot
Clinical guidelines and strategic plan for the prevention, diagnosis and treatment of delirium: The zero delirium project
inferred← citeshttps://doi.org/10.1016/j.smrv.2024.102016openalex-snapshot
Novel applications of sleep pharmacology as delirium therapeutics
inferred← citeshttps://doi.org/10.1093/ajhp/zxae224openalex-snapshot
A pharmacist’s guide to mitigating sleep dysfunction and promoting good sleep in the intensive care unit
inferred← citeshttps://doi.org/10.1097/ccm.0000000000007011openalex-snapshot
Remimazolam Besylate Versus Dexmedetomidine As a Sedative in ICU Patients Undergoing Mechanical Ventilation: A Multicenter, Single-blinded, Randomized, Noninferiority Trial
inferred← citeshttps://doi.org/10.1111/aas.14190openalex-snapshot
Subjective sleep assessment compared to polysomnography in mechanically ventilated critically ill ICU patients
inferred← citeshttps://doi.org/10.1111/nicc.70482openalex-snapshot
Clinical Care Interaction and Patient Sleep in the Intensive Care Unit: A Secondary Data Analysis
inferred← citeshttps://doi.org/10.1136/bmjopen-2025-107084openalex-snapshot
Intranasal dexmedetomidine for perioperative sleep disturbance: a protocol for a systematic review with meta-analysis and trial sequential analysis
inferred← citeshttps://doi.org/10.1136/thorax-2023-220036openalex-snapshot
Intensive care unit interventions to promote sleep and circadian biology in reducing incident delirium: a scoping review
inferred← citeshttps://doi.org/10.1152/ajplung.00210.2024openalex-snapshot
Development of a preclinical model of ICU-associated sleep fragmentation and effects on pneumonia recovery in mice
inferred← citeshttps://doi.org/10.1164/rccm.202301-0184stopenalex-snapshot
Causes, Consequences, and Treatments of Sleep and Circadian Disruption in the ICU: An Official American Thoracic Society Research Statement
inferred← citeshttps://doi.org/10.1177/08850666241255345openalex-snapshot
Pharmacologic Sleep Aids in the Intensive Care Unit: A Systematic Review
inferred← citeshttps://doi.org/10.1186/s12871-023-02048-6openalex-snapshot
Effects of dexmedetomidine on postoperative sleep quality: a systematic review and meta-analysis of randomized controlled trials
inferred← citeshttps://doi.org/10.1186/s13054-026-06151-1openalex-snapshot
Effect of the orexin receptor antagonist, suvorexant, on sleep architecture in the early postoperative period following cardiac surgery: a randomized controlled trial
inferred← citeshttps://doi.org/10.1213/ane.0000000000007548openalex-snapshot
A Randomized Clinical Trial of Dexmedetomidine on Delirium, Cognitive Dysfunction, and Sleep After Non-Ambulatory Orthopedic Surgery With Regional Anesthesia
inferred← citeshttps://doi.org/10.2147/ijgm.s513018openalex-snapshot
Distinct Trajectories of Fatigue Among Families with Post-Intensive Care Syndrome
inferred← citeshttps://doi.org/10.2174/011570159x368375250611103614openalex-snapshot
Therapeutic Potential of Anesthesiology for Sleep Disorders in the Perioperative Period
inferred← citeshttps://doi.org/10.2478/jccm-2024-0043openalex-snapshot
Effect of sleep quality on weaning from mechanical ventilation: A scoping review
inferred← citeshttps://doi.org/10.3389/fmed.2023.1199685openalex-snapshot
Sleep and critical illness: a review
inferred← citeshttps://doi.org/10.3389/fneur.2026.1814615openalex-snapshot
Pharmacotherapy for sleep during critical illness and beyond
inferred← citeshttps://doi.org/10.3389/frsle.2025.1629408openalex-snapshot
Sleep fragmentation in critically ill children: a review of contributing factors in the pediatric intensive care unit and neurodevelopmental outcomes
inferred← citeshttps://doi.org/10.3390/clockssleep7030031openalex-snapshot
Translation and Validation of the Richards–Campbell Sleep Questionnaire for Intensive Care Unit Patients in Morocco: Reliability and Validity Assessment
inferred← citeshttps://doi.org/10.3390/jpm13121641openalex-snapshot
Sedation for Patients with Sepsis: Towards a Personalised Approach
inferred← citeshttps://doi.org/10.3918/jsicm.31_485openalex-snapshot
Usage of sedatives for delirious patients and its ethical problems in ICU
inferred← citeshttps://doi.org/10.7759/cureus.96219openalex-snapshot
Dexmedetomidine for Managing Delirium and Agitation in Patients Admitted to Intensive Care Units: A Bibliometric Analysis
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