On the public citation graph

Integration analysis of GWAS and expression quantitative trait loci to identify candidate genes and pathways for clozapine‐related neutropaenia

https://doi.org/10.1111/bcp.15043
0 signed · 49 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.
Claim with ORCID
Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.
See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/archpsyc.1988.01800330013001openalex-snapshot
Clozapine for the Treatment-Resistant Schizophrenic
inferredcites →https://doi.org/10.1001/jamapsychiatry.2017.1322openalex-snapshot
Real-World Effectiveness of Antipsychotic Treatments in a Nationwide Cohort of 29 823 Patients With Schizophrenia
inferredcites →https://doi.org/10.1002/hup.1176openalex-snapshot
Correlation of adenosinergic activity with superior efficacy of clozapine for treatment of chronic schizophrenia: a double blind randomised trial
inferredcites →https://doi.org/10.1002/jlb.3vma0918-374ropenalex-snapshot
Adenosine from a biologic source regulates neutrophil extracellular traps (NETs)
inferredcites →https://doi.org/10.1007/s00044-015-1484-8openalex-snapshot
Structure and toxicity of clozapine and olanzapine on agranulocytosis
inferredcites →https://doi.org/10.1016/j.ajhg.2010.11.011openalex-snapshot
GCTA: A Tool for Genome-wide Complex Trait Analysis
inferredcites →https://doi.org/10.1016/j.ajhg.2020.03.002openalex-snapshot
Genetic Architecture of Gene Expression in European and African Americans: An eQTL Mapping Study in GENOA
inferredcites →https://doi.org/10.1016/j.biopsych.2015.12.006openalex-snapshot
Pharmacogenomic Study of Clozapine-Induced Agranulocytosis/Granulocytopenia in a Japanese Population
inferredcites →https://doi.org/10.1016/j.celrep.2019.05.065openalex-snapshot
Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation
inferredcites →https://doi.org/10.1016/j.neulet.2006.11.071openalex-snapshot
Increased serum adenosine deaminase activity in schizophrenic receiving antipsychotic treatment
inferredcites →https://doi.org/10.1016/s0022-3565(25)12207-6openalex-snapshot
Clozapine is oxidized by activated human neutrophils to a reactive nitrenium ion that irreversibly binds to the cells.
inferredcites →https://doi.org/10.1016/s0026-895x(24)13269-5openalex-snapshot
A Comparison of the Covalent Binding of Clozapine and Olanzapine to Human Neutrophils In Vitro and In Vivo
inferredcites →https://doi.org/10.1016/s0140-6736(08)61764-xopenalex-snapshot
Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis
inferredcites →https://doi.org/10.1017/s0033291716002014openalex-snapshot
Two distinct patterns of treatment resistance: clinical predictors of treatment resistance in first-episode schizophrenia spectrum psychoses
inferredcites →https://doi.org/10.1017/s0033291717000435openalex-snapshot
Antipsychotic treatment resistance in first-episode psychosis: prevalence, subtypes and predictors
inferredcites →https://doi.org/10.1023/a:1015934104984openalex-snapshot
Idiosyncratic Drug Reactions: Possible Role of Reactive Metabolites Generated by Leukocytes
inferredcites →https://doi.org/10.1038/mp.2016.97openalex-snapshot
Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia
inferredcites →https://doi.org/10.1038/ncomms5757openalex-snapshot
Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles
inferredcites →https://doi.org/10.1038/nri1841openalex-snapshot
Neutrophil serine proteases: specific regulators of inflammation
inferredcites →https://doi.org/10.1038/s41380-018-0335-7openalex-snapshot
A genome-wide association study in individuals of African ancestry reveals the importance of the Duffy-null genotype in the assessment of clozapine-related neutropenia
inferredcites →https://doi.org/10.1038/s41386-020-0605-3openalex-snapshot
Integration analysis of methylation quantitative trait loci and GWAS identify three schizophrenia risk variants
inferredcites →https://doi.org/10.1038/s41467-020-17668-6openalex-snapshot
Testing and controlling for horizontal pleiotropy with probabilistic Mendelian randomization in transcriptome-wide association studies
inferredcites →https://doi.org/10.1038/tpj.2017.6openalex-snapshot
More than 25 years of genetic studies of clozapine-induced agranulocytosis
inferredcites →https://doi.org/10.1073/pnas.90.20.9417openalex-snapshot
Cloning and molecular characterization of a human intracellular serine proteinase inhibitor.
inferredcites →https://doi.org/10.1074/jbc.271.3.1605openalex-snapshot
Proteinase Inhibitor 6 Cannot Be Secreted, Which Suggests It Is a New Type of Cellular Serpin
inferredcites →https://doi.org/10.1080/14740338.2016.1191468openalex-snapshot
Clozapine’s critical role in treatment resistant schizophrenia: ensuring both safety and use
inferredcites →https://doi.org/10.1093/hmg/ddz263openalex-snapshot
Colocalization of GWAS and eQTL signals at loci with multiple signals identifies additional candidate genes for body fat distribution
inferredcites →https://doi.org/10.1093/schbul/sbl068openalex-snapshot
Clozapine Underutilization and Discontinuation in African Americans Due to Leucopenia
inferredcites →https://doi.org/10.1097/00008571-200103000-00004openalex-snapshot
Further evidence of human leukocyte antigen-encoded susceptibility to clozapine-induced agranulocytosis independent of ancestry
inferredcites →https://doi.org/10.1111/acps.12233openalex-snapshot
Discontinuation of clozapine: a 15‐year naturalistic retrospective study of 320 patients
inferredcites →https://doi.org/10.1161/atvbaha.111.226845openalex-snapshot
Regulation of Neutrophil Function by Adenosine
inferredcites →https://doi.org/10.1164/rccm.201707-1434ocopenalex-snapshot
Human Lung DNA Methylation Quantitative Trait Loci Colocalize with Chronic Obstructive Pulmonary Disease Genome-Wide Association Loci
inferredcites →https://doi.org/10.1176/ajp.154.4.475openalex-snapshot
Age at onset and gender of schizophrenic patients in relation to neuroleptic resistance
inferredcites →https://doi.org/10.1176/ajp.2006.163.4.600openalex-snapshot
Effectiveness of Clozapine Versus Olanzapine, Quetiapine, and Risperidone in Patients With Chronic Schizophrenia Who Did Not Respond to Prior Atypical Antipsychotic Treatment
inferredcites →https://doi.org/10.1176/appi.ajp.159.4.567openalex-snapshot
Racial Disparities in Antipsychotic Prescription Patterns for Patients With Schizophrenia
inferredcites →https://doi.org/10.1182/blood.v86.3.1177.1177openalex-snapshot
HLA associations in clozapine-induced agranulocytosis
inferredcites →https://doi.org/10.1182/blood.v93.6.2089.406k10_2089_2097openalex-snapshot
The Intracellular Serpin Proteinase Inhibitor 6 Is Expressed in Monocytes and Granulocytes and Is a Potent Inhibitor of the Azurophilic Granule Protease, Cathepsin G
inferredcites →https://doi.org/10.1192/bjp.175.6.576openalex-snapshot
Active monitoring of 12760 clozapine recipients in the UK and Ireland
inferredcites →https://doi.org/10.1192/bjp.bp.115.177261openalex-snapshot
Clozapine v . first- and second-generation antipsychotics in treatment-refractory schizophrenia: systematic review and meta-analysis
inferredcites →https://doi.org/10.1371/journal.pgen.1004383openalex-snapshot
Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
inferredcites →https://doi.org/10.3109/10401239509149622openalex-snapshot
Risk Factors for Clozapine Discontinuation Among 805 Patients in the VA Hospital System
inferredcites →https://doi.org/10.3389/fimmu.2018.00813openalex-snapshot
Controlling the Immune Suppressor: Transcription Factors and MicroRNAs Regulating CD73/NT5E
inferredcites →https://doi.org/10.4088/jcp.09m05527yelopenalex-snapshot
Candidate Gene Analysis Identifies a Polymorphism inHLA-DQB1Associated With Clozapine-Induced Agranulocytosis
inferredcites →https://doi.org/10.4088/jcp.v67n0911openalex-snapshot
Clozapine Utilization and Outcomes by Race in a Public Mental Health System: 1994-2000

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4089530openalex-extracted
Clozapine's Multiple Cellular Mechanisms: What Do We Know after More than Fifty Years? a Systematic Review and Critical Assessment of Translational Mechanisms Relevant for Innovative Strategies in Treatment-Resistant Schizophrenia
inferred← citeshttps://doi.org/10.1007/978-1-0716-3354-0openalex-snapshot
Plant Gene Regulatory Networks
inferred← citeshttps://doi.org/10.1007/978-1-0716-3354-0_18openalex-snapshot
Predicting Gene Regulatory Interactions Using Natural Genetic Variation
inferred← citeshttps://doi.org/10.1007/s12031-026-02505-0openalex-snapshot
Genetic Variations in the Dopaminergic Signaling Pathways and Their Implications for Antipsychotics Pharmacogenetics
inferred← citeshttps://doi.org/10.1111/bcp.15114openalex-snapshot
Integration of innovative statistical methods using genetic data provides pharmacological insight and facilitates drug development
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.