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Osteosarcoma mechanobiology and therapeutic targets

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ar.23571openalex-snapshot
Collagen Fiber Orientation in Primate Long Bones
inferredcites →https://doi.org/10.1002/ar.a.20334openalex-snapshot
Multiple roles for emerin: Implications for Emery‐Dreifuss muscular dystrophy
inferredcites →https://doi.org/10.1002/bit.22361openalex-snapshot
Hydrogels as extracellular matrix mimics for 3D cell culture
inferredcites →https://doi.org/10.1002/ijc.33046openalex-snapshot
Histone deacetylase inhibition prevents the growth of primary and metastatic osteosarcoma
inferredcites →https://doi.org/10.1002/jbm.b.20035openalex-snapshot
Hierarchically biomimetic bone scaffold materials: Nano‐HA/collagen/PLA composite
inferredcites →https://doi.org/10.1002/jbmr.2182openalex-snapshot
Bisphosphonates Inhibit Osteosarcoma-Mediated Osteolysis Via Attenuation of Tumor Expression of MCP-1 and RANKL
inferredcites →https://doi.org/10.1002/jbmr.2340openalex-snapshot
Modifications to Nano- and Microstructural Quality and the Effects on Mechanical Integrity in Paget's Disease of Bone
inferredcites →https://doi.org/10.1002/jbmr.455openalex-snapshot
Formulated siRNAs targeting Rankl prevent osteolysis and enhance chemotherapeutic response in osteosarcoma models
inferredcites →https://doi.org/10.1002/jcb.24708openalex-snapshot
Wnt Pathway in Osteosarcoma, from Oncogenic to Therapeutic
inferredcites →https://doi.org/10.1002/jcp.29967openalex-snapshot
The Hippo in the room: Targeting the Hippo signalling pathway for osteosarcoma therapies
inferredcites →https://doi.org/10.1002/mabi.202000370openalex-snapshot
Stiffness of Nanoparticulate Mineralized Collagen Scaffolds Triggers Osteogenesis via Mechanotransduction and Canonical Wnt Signaling
inferredcites →https://doi.org/10.1002/stem.1647openalex-snapshot
Bone Environment is Essential for Osteosarcoma Development from Transformed Mesenchymal Stem Cells
inferredcites →https://doi.org/10.1002/stem.2090openalex-snapshot
Intranuclear Actin Regulates Osteogenesis
inferredcites →https://doi.org/10.1002/wnan.1443openalex-snapshot
Beyond quantification: in situ analysis of transcriptome and pre‐ mRNA alternative splicing at the nanoscale
inferredcites →https://doi.org/10.1007/s00198-005-2035-9openalex-snapshot
The role of collagen in bone strength
inferredcites →https://doi.org/10.1007/s00223-008-9104-yopenalex-snapshot
Aminobisphosphonates Cause Osteoblast Apoptosis and Inhibit Bone Nodule Formation In Vitro
inferredcites →https://doi.org/10.1007/s00223-019-00522-3openalex-snapshot
Paget’s Disease of Bone
inferredcites →https://doi.org/10.1007/s002230001211openalex-snapshot
Mutation Screening of the TNFRSF11A Gene Encoding Receptor Activator of NFkB (RANK) in Familial and Sporadic Paget's Disease of Bone and Osteosarcoma
inferredcites →https://doi.org/10.1007/s10278-018-0145-0openalex-snapshot
Bone-Cancer Assessment and Destruction Pattern Analysis in Long-Bone X-ray Image
inferredcites →https://doi.org/10.1007/s10585-012-9543-8openalex-snapshot
Dynamic analysis of lung metastasis by mouse osteosarcoma LM8: VEGF is a candidate for anti-metastasis therapy
inferredcites →https://doi.org/10.1007/s11914-016-0303-6openalex-snapshot
Bone Quality in Paget’s Disease of Bone
inferredcites →https://doi.org/10.1007/s11914-016-0319-yopenalex-snapshot
Cortical Bone Porosity: What Is It, Why Is It Important, and How Can We Detect It?
inferredcites →https://doi.org/10.1016/j.actbio.2019.05.031openalex-snapshot
The inclusion of zinc into mineralized collagen scaffolds for craniofacial bone repair applications
inferredcites →https://doi.org/10.1016/j.bbcan.2012.07.003openalex-snapshot
The role of osteoclasts and tumour-associated macrophages in osteosarcoma metastasis
inferredcites →https://doi.org/10.1016/j.bcp.2018.06.015openalex-snapshot
Connective tissue growth factor stimulates osteosarcoma cell migration and induces osteosarcoma metastasis by upregulating VCAM-1 expression
inferredcites →https://doi.org/10.1016/j.bioactmat.2018.05.006openalex-snapshot
Bioactive hydrogels for bone regeneration
inferredcites →https://doi.org/10.1016/j.biomaterials.2015.01.023openalex-snapshot
Cytoskeletal tension induces the polarized architecture of the nucleus
inferredcites →https://doi.org/10.1016/j.bone.2017.01.004openalex-snapshot
Disruption of collagen/apatite alignment impairs bone mechanical function in osteoblastic metastasis induced by prostate cancer
inferredcites →https://doi.org/10.1016/j.canlet.2016.11.019openalex-snapshot
Cancer stem cells in osteosarcoma
inferredcites →https://doi.org/10.1016/j.cell.2017.10.008openalex-snapshot
Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores
inferredcites →https://doi.org/10.1016/j.cellsig.2019.109382openalex-snapshot
On the relationship of YAP and FAK in hMSCs and osteosarcoma cells: Discrimination of FAK modulation by nuclear YAP depletion or YAP silencing
inferredcites →https://doi.org/10.1016/j.cub.2014.07.034openalex-snapshot
Regulation of YAP by Mechanical Strain through Jnk and Hippo Signaling
inferredcites →https://doi.org/10.1016/j.ijbiomac.2018.11.003openalex-snapshot
NF-κB signaling and integrin-β1 inhibition attenuates osteosarcoma metastasis via increased cell apoptosis
inferredcites →https://doi.org/10.1016/j.jbo.2012.03.001openalex-snapshot
Anti-RANKL therapy for bone tumours: Basic, pre-clinical and clinical evidences
inferredcites →https://doi.org/10.1016/j.jbo.2020.100321openalex-snapshot
Expression profiling of DNA methyl transferase I (DNMT1) and efficacy of a DNA-hypomethylating agent (decitabine) in combination with chemotherapy in osteosarcoma
inferredcites →https://doi.org/10.1016/j.jbspin.2010.07.010openalex-snapshot
Genetics of bone diseases: Paget's disease, fibrous dysplasia, osteopetrosis, and osteogenesis imperfecta
inferredcites →https://doi.org/10.1016/j.jmbbm.2016.10.017openalex-snapshot
Modifying the strength and strain concentration profile within collagen scaffolds using customizable arrays of poly-lactic acid fibers
inferredcites →https://doi.org/10.1016/j.ocl.2015.08.022openalex-snapshot
Update on Survival in Osteosarcoma
inferredcites →https://doi.org/10.1016/j.yexcr.2015.08.001openalex-snapshot
Osteoprotegerin activates osteosarcoma cells that co-express RANK and RANKL
inferredcites →https://doi.org/10.1016/j.yexcr.2017.08.035openalex-snapshot
Combining 2D angiogenesis and 3D osteosarcoma microtissues to improve vascularization
inferredcites →https://doi.org/10.1016/s0006-3495(00)76279-5openalex-snapshot
Cell Movement Is Guided by the Rigidity of the Substrate
inferredcites →https://doi.org/10.1016/s0021-9290(98)00177-8openalex-snapshot
The elastic properties of trabecular and cortical bone tissues are similar: results from two microscopic measurement techniques
inferredcites →https://doi.org/10.1016/s1470-2045(16)30096-1openalex-snapshot
Zoledronate in combination with chemotherapy and surgery to treat osteosarcoma (OS2006): a randomised, multicentre, open-label, phase 3 trial
inferredcites →https://doi.org/10.1016/s1525-1578(10)60669-1openalex-snapshot
Inheritance of Osteosarcoma and Paget's Disease of Bone
inferredcites →https://doi.org/10.1021/acsami.0c00275openalex-snapshot
Intrafibrillar Mineralized Collagen–Hydroxyapatite-Based Scaffolds for Bone Regeneration
inferredcites →https://doi.org/10.1021/acsami.6b06489openalex-snapshot
Biodegradation and Osteosarcoma Cell Cultivation on Poly(aspartic acid) Based Hydrogels
inferredcites →https://doi.org/10.1021/acssensors.7b00359openalex-snapshot
Real-Time Multiplex Kinase Phosphorylation Sensors in Living Cells
inferredcites →https://doi.org/10.1038/21674openalex-snapshot
The TAK1–NLK–MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF
inferredcites →https://doi.org/10.1038/modpathol.2010.77openalex-snapshot
Phosphorylated ezrin is located in the nucleus of the osteosarcoma cell
inferredcites →https://doi.org/10.1038/ncb2615openalex-snapshot
YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29
inferredcites →https://doi.org/10.1038/ncb3387openalex-snapshot
Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment
inferredcites →https://doi.org/10.1038/nrendo.2013.137openalex-snapshot
Osteopetrosis: genetics, treatment and new insights into osteoclast function
inferredcites →https://doi.org/10.1038/nrm.2017.87openalex-snapshot
Mechanobiology of YAP and TAZ in physiology and disease
inferredcites →https://doi.org/10.1038/nrm3897openalex-snapshot
Physical influences of the extracellular environment on cell migration
inferredcites →https://doi.org/10.1038/onc.2008.437openalex-snapshot
The actin-cytoskeleton linker protein ezrin is regulated during osteosarcoma metastasis by PKC
inferredcites →https://doi.org/10.1038/onc.2009.206openalex-snapshot
Beta4 integrin promotes osteosarcoma metastasis and interacts with ezrin
inferredcites →https://doi.org/10.1038/onc.2011.245openalex-snapshot
Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells
inferredcites →https://doi.org/10.1038/onc.2013.179openalex-snapshot
Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA
inferredcites →https://doi.org/10.1038/s41413-018-0036-5openalex-snapshot
Efficacy of an orally active small-molecule inhibitor of RANKL in bone metastasis
inferredcites →https://doi.org/10.1038/s41580-018-0086-yopenalex-snapshot
Hippo–YAP/TAZ signalling in organ regeneration and regenerative medicine
inferredcites →https://doi.org/10.1038/s41591-018-0158-8openalex-snapshot
Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4
inferredcites →https://doi.org/10.1038/s41598-020-72552-zopenalex-snapshot
A multiple drug loaded, functionalized pH-sensitive nanocarrier as therapeutic and epigenetic modulator for osteosarcoma
inferredcites →https://doi.org/10.1038/s41598-020-75833-9openalex-snapshot
Cell geometry and the cytoskeleton impact the nucleo-cytoplasmic localisation of the SMYD3 methyltransferase
inferredcites →https://doi.org/10.1038/srep00555openalex-snapshot
Actin cap associated focal adhesions and their distinct role in cellular mechanosensing
inferredcites →https://doi.org/10.1038/srep12999openalex-snapshot
Enhancer of zeste homolog 2 silencing inhibits tumor growth and lung metastasis in osteosarcoma
inferredcites →https://doi.org/10.1039/c9bm02075fopenalex-snapshot
Hydrogel 3D in vitro tumor models for screening cell aggregation mediated drug response
inferredcites →https://doi.org/10.1039/d0ra03872eopenalex-snapshot
Sequential sequestrations increase the incorporation and retention of multiple growth factors in mineralized collagen scaffolds
inferredcites →https://doi.org/10.1051/sicotj/2017028openalex-snapshot
Osteosarcoma: a comprehensive review
inferredcites →https://doi.org/10.1073/pnas.1221637110openalex-snapshot
Orientation-specific responses to sustained uniaxial stretching in focal adhesion growth and turnover
inferredcites →https://doi.org/10.1073/pnas.1504837112openalex-snapshot
Mechanical stimulation induces formin-dependent assembly of a perinuclear actin rim
inferredcites →https://doi.org/10.1073/pnas.1603316113openalex-snapshot
Pamidronate functionalized nanoconjugates for targeted therapy of focal skeletal malignant osteolysis
inferredcites →https://doi.org/10.1073/pnas.1605317113openalex-snapshot
Intratumoral oxygen gradients mediate sarcoma cell invasion
inferredcites →https://doi.org/10.1073/pnas.96.13.7300openalex-snapshot
Ezrin, a plasma membrane–microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway
inferredcites →https://doi.org/10.1074/jbc.272.15.9755openalex-snapshot
Characterization of Urinary Degradation Products Derived from Type I Collagen
inferredcites →https://doi.org/10.1074/jbc.m116.718189openalex-snapshot
Ezrin Inhibition Up-regulates Stress Response Gene Expression
inferredcites →https://doi.org/10.1074/jbc.m412817200openalex-snapshot
Bisphosphonates and Estrogens Inhibit Osteocyte Apoptosis via Distinct Molecular Mechanisms Downstream of Extracellular Signal-regulated Kinase Activation
inferredcites →https://doi.org/10.1083/jcb.201806065openalex-snapshot
YAP and TAZ limit cytoskeletal and focal adhesion maturation to enable persistent cell motility
inferredcites →https://doi.org/10.1086/323798openalex-snapshot
Genomewide Search in Familial Paget Disease of Bone Shows Evidence of Genetic Heterogeneity with Candidate Loci on Chromosomes 2q36, 10p13, and 5q35
inferredcites →https://doi.org/10.1086/338658openalex-snapshot
Linkage of Paget Disease of Bone to a Novel Region on Human Chromosome 18q23
inferredcites →https://doi.org/10.1089/ten.teb.2019.0243openalex-snapshot
Mechanical Roles in Formation of Oriented Collagen Fibers
inferredcites →https://doi.org/10.1091/mbc.e14-12-1584openalex-snapshot
Ezrin regulates focal adhesion and invadopodia dynamics by altering calpain activity to promote breast cancer cell invasion
inferredcites →https://doi.org/10.1093/nar/gkv098openalex-snapshot
Dissecting the behavior and function of MBD3 in DNA methylation homeostasis by single-molecule spectroscopy and microscopy
inferredcites →https://doi.org/10.1096/fj.201900131ropenalex-snapshot
Crosshatch nanofiber networks of tunable interfiber spacing induce plasticity in cell migration and cytoskeletal response
inferredcites →https://doi.org/10.1097/01.blo.0000188063.56091.69openalex-snapshot
Aberrant Methylation of p14ARF Gene Correlates with Poor Survival in Osteosarcoma
inferredcites →https://doi.org/10.1097/cad.0000000000000418openalex-snapshot
Suberanilohydroxamic acid (vorinostat) synergistically enhances the cytotoxicity of doxorubicin and cisplatin in osteosarcoma cell lines
inferredcites →https://doi.org/10.1111/bph.15541openalex-snapshot
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors
inferredcites →https://doi.org/10.1111/bph.15542openalex-snapshot
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes
inferredcites →https://doi.org/10.1111/bph.15713openalex-snapshot
Osteosarcoma mechanobiology and therapeutic targets
inferredcites →https://doi.org/10.1111/j.1532-950x.1992.tb00069.xopenalex-snapshot
Canine Axial Skeletal Osteosarcoma A Retrospective Study of 116 Cases (1986 to 1989)
inferredcites →https://doi.org/10.1111/j.1939-1676.2001.tb01242.xopenalex-snapshot
Retrospective Analysis of Axial Skeleton Osteosarcoma in 22 Large-Breed Dogs
inferredcites →https://doi.org/10.1111/vco.12741openalex-snapshot
A retrospective analysis of 11 dogs with surface osteosarcoma
inferredcites →https://doi.org/10.1126/sciadv.aaw4991openalex-snapshot
Osteoprotegerin reduces osteoclast resorption activity without affecting osteogenesis on nanoparticulate mineralized collagen scaffolds
inferredcites →https://doi.org/10.1126/sciadv.aay6515openalex-snapshot
Nuclear actin regulates inducible transcription by enhancing RNA polymerase II clustering
inferredcites →https://doi.org/10.1155/2012/627254openalex-snapshot
The Genetics of Osteosarcoma
inferredcites →https://doi.org/10.1155/2015/290368openalex-snapshot
The HDAC Inhibitor Vorinostat Diminishes theIn VitroMetastatic Behavior of Osteosarcoma Cells
inferredcites →https://doi.org/10.1158/0008-5472.can-09-4291openalex-snapshot
Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases
inferredcites →https://doi.org/10.1158/0008-5472.can-18-1255openalex-snapshot
Activation of Estrogen Receptor Alpha by Decitabine Inhibits Osteosarcoma Growth and Metastasis
inferredcites →https://doi.org/10.1158/1055-9965.epi-05-0909openalex-snapshot
Alpha CTX as a Biomarker of Skeletal Invasion of Breast Cancer: Immunolocalization and the Load Dependency of Urinary Excretion
inferredcites →https://doi.org/10.1158/1078-0432.ccr-05-1933openalex-snapshot
A study of the biological receptor activator of nuclear factor-kappaB ligand inhibitor, denosumab, in patients with multiple myeloma or bone metastases from breast cancer.
inferredcites →https://doi.org/10.1158/1538-7445.am2020-2917openalex-snapshot
Abstract 2917: Antitumor effects of an epigenetic inhibitor, 4SC-202, on human osteosarcoma cells
inferredcites →https://doi.org/10.1159/000331743openalex-snapshot
Stretch-inducible Expression of Connective Tissue Growth Factor (CTGF) in Human Osteoblasts-like Cells is Mediated by PI3K-JNK Pathway
inferredcites →https://doi.org/10.1186/1471-2407-14-450openalex-snapshot
The genetic basis for inactivation of Wnt pathway in human osteosarcoma
inferredcites →https://doi.org/10.1186/1746-6148-8-56openalex-snapshot
Prognostic factors in canine appendicular osteosarcoma – a meta-analysis
inferredcites →https://doi.org/10.1186/jbiol22openalex-snapshot
Dishevelled and Wnt signaling: is the nucleus the final frontier?
inferredcites →https://doi.org/10.1186/s13148-018-0605-xopenalex-snapshot
Elevated H3K27me3 levels sensitize osteosarcoma to cisplatin
inferredcites →https://doi.org/10.1186/s13148-019-0620-6openalex-snapshot
Epigenetic biomarker screening by FLIM-FRET for combination therapy in ER+ breast cancer
inferredcites →https://doi.org/10.1359/jbmr.040602openalex-snapshot
Susceptibility to Paget's Disease of Bone Is Influenced by a Common Polymorphic Variant of Osteoprotegerin
inferredcites →https://doi.org/10.1359/jbmr.06s206openalex-snapshot
Contribution of Genetic Factors to the Pathogenesis of Paget's Disease of Bone and Related Disorders
inferredcites →https://doi.org/10.1359/jbmr.06s211openalex-snapshot
Osteosarcoma in Paget's Disease of Bone
inferredcites →https://doi.org/10.1359/jbmr.1997.12.9.1407openalex-snapshot
Decreased β-Isomerization of the C-Terminal Telopeptide of Type I Collagen α1 Chain in Paget's Disease of Bone
inferredcites →https://doi.org/10.1359/jbmr.2003.18.8.1381openalex-snapshot
Phenotypic Characterization of Early Onset Paget's Disease of Bone Caused by a 27-bp Duplication in the TNFRSF11A Gene
inferredcites →https://doi.org/10.1371/journal.pone.0095596openalex-snapshot
Separate and Combined Effects of DNMT and HDAC Inhibitors in Treating Human Multi-Drug Resistant Osteosarcoma HosDXR150 Cell Line
inferredcites →https://doi.org/10.1371/journal.pone.0097381openalex-snapshot
Micro-Computed Tomography Derived Anisotropy Detects Tumor Provoked Deviations in Bone in an Orthotopic Osteosarcoma Murine Model
inferredcites →https://doi.org/10.1371/journal.pone.0132377openalex-snapshot
RETRACTED: Optimum 3D Matrix Stiffness for Maintenance of Cancer Stem Cells Is Dependent on Tissue Origin of Cancer Cells
inferredcites →https://doi.org/10.1387/ijdb.190019usopenalex-snapshot
On the biomechanical properties of osteosarcoma cells and their environment
inferredcites →https://doi.org/10.14670/hh-24.235openalex-snapshot
Receptor activator of nuclear factor-kappa B ligand (RANKL) stimulates bone-associated tumors through functional RANK expressed on bone-associated cancer cells?
inferredcites →https://doi.org/10.1586/era.11.94openalex-snapshot
The Wnt signaling pathway: implications for therapy in osteosarcoma
inferredcites →https://doi.org/10.18632/oncotarget.25484openalex-snapshot
Frequent epigenetic alterations in polycomb repressive complex 2 in osteosarcoma cell lines
inferredcites →https://doi.org/10.18632/oncotarget.26377openalex-snapshot
Targeting the Wnt/β-catenin pathway in human osteosarcoma cells
inferredcites →https://doi.org/10.18632/oncotarget.27669openalex-snapshot
Can Denosumab be used in combination with Doxorubicin in Osteosarcoma?
inferredcites →https://doi.org/10.18632/oncotarget.9518openalex-snapshot
Overexpression of EZH2 is associated with the poor prognosis in osteosarcoma and function analysis indicates a therapeutic potential
inferredcites →https://doi.org/10.21037/atm.2016.12.10openalex-snapshot
RANKL inhibitors for osteosarcoma treatment: hope and caution
inferredcites →https://doi.org/10.2147/ott.s105418openalex-snapshot
Histone deacetylase inhibitor sodium butyrate suppresses proliferation and promotes apoptosis in osteosarcoma cells by regulation of the MDM2–p53 signaling
inferredcites →https://doi.org/10.2174/1568009611313040005openalex-snapshot
The Histone Deacetylase Inhibitor, MS-275 (Entinostat), Downregulates c-FLIP, Sensitizes Osteosarcoma Cells to FasL, and Induces the Regression of Osteosarcoma Lung Metastases
inferredcites →https://doi.org/10.2217/fon-2019-0170openalex-snapshot
Excess of Second Tumors in Denosumab-Treated Patients: A Metabolic Hypothesis
inferredcites →https://doi.org/10.22203/ecm.v033a14openalex-snapshot
Clinical use of stem cells in orthopaedics
inferredcites →https://doi.org/10.22203/ecm.v033a17openalex-snapshot
Cyclic tensile strain enhances human mesenchymal stem cell Smad 2/3 activation and tenogenic differentiation in anisotropic collagen-glycosaminoglycan scaffolds
inferredcites →https://doi.org/10.2320/matertrans.m2016341openalex-snapshot
Disruption of Collagen Matrix Alignment in Osteolytic Bone Metastasis Induced by Breast Cancer
inferredcites →https://doi.org/10.3389/fcell.2020.00678openalex-snapshot
Cofilin-1 Is a Mechanosensitive Regulator of Transcription
inferredcites →https://doi.org/10.3389/fgene.2017.00027openalex-snapshot
Nuclear Actin in Development and Transcriptional Reprogramming
inferredcites →https://doi.org/10.3389/fonc.2020.00013openalex-snapshot
Understanding and Modeling Metastasis Biology to Improve Therapeutic Strategies for Combating Osteosarcoma Progression
inferredcites →https://doi.org/10.3390/cancers12123847openalex-snapshot
The YAP/TEAD Axis as a New Therapeutic Target in Osteosarcoma: Effect of Verteporfin and CA3 on Primary Tumor Growth
inferredcites →https://doi.org/10.3390/cancers13040683openalex-snapshot
Mechanisms of Resistance to Conventional Therapies for Osteosarcoma
inferredcites →https://doi.org/10.3390/ijms20153751openalex-snapshot
New Insights about the Wnt/β-Catenin Signaling Pathway in Primary Bone Tumors and Their Microenvironment: A Promising Target to Develop Therapeutic Strategies?
inferredcites →https://doi.org/10.3390/ijms21207595openalex-snapshot
Targeting Mechanotransduction in Osteosarcoma: A Comparative Oncology Perspective
inferredcites →https://doi.org/10.3390/ijms22042162openalex-snapshot
Integrin-Linked Kinase Links Integrin Activation to Invadopodia Function and Invasion via the p(T567)-Ezrin/NHERF1/NHE1 Pathway
inferredcites →https://doi.org/10.3390/nano10081511openalex-snapshot
Hydrogel as a Biomaterial for Bone Tissue Engineering: A Review
inferredcites →https://doi.org/10.3390/ph14030260openalex-snapshot
Potential Antimetastatic Effect of Timosaponin AIII against Human Osteosarcoma Cells through Regulating the Integrin/FAK/Cofilin Axis
inferredcites →https://doi.org/10.3390/polym8020042openalex-snapshot
Application of Collagen Scaffold in Tissue Engineering: Recent Advances and New Perspectives
inferredcites →https://doi.org/10.3892/mmr.2015.4701openalex-snapshot
Downregulation of connective tissue growth factor reduces migration and invasiveness of osteosarcoma cells
inferredcites →https://doi.org/10.3892/ol.2013.1655openalex-snapshot
Downregulation of ERK signaling impairs U2OS osteosarcoma cell migration in collagen matrix by suppressing MMP9 production
inferredcites →https://doi.org/10.3892/ol.2017.6972openalex-snapshot
Expression of NF-κB and PTEN in osteosarcoma and its clinical significance
inferredcites →https://doi.org/10.4065/83.9.1032openalex-snapshot
Bisphosphonates: Mechanism of Action and Role in Clinical Practice
inferredcites →https://doi.org/10.4161/org.4.2.5851openalex-snapshot
Wnt signal transduction pathways
inferredcites →https://doi.org/10.7150/ijbs.16569openalex-snapshot
Histone Deacetylase Inhibitor Trichostatin a Promotes the Apoptosis of Osteosarcoma Cells through p53 Signaling Pathway Activation
inferredcites →https://doi.org/10.7150/thno.40889openalex-snapshot
A combat with the YAP/TAZ-TEAD oncoproteins for cancer therapy
inferredcites →https://doi.org/10.7150/thno.53347openalex-snapshot
KDM6B-mediated histone demethylation of LDHA promotes lung metastasis of osteosarcoma

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4661833openalex-extracted
Oligopeptide Modified ICG/Cisplatin@CaCO 3 for Targeted Osteosarcoma NIR-II Imaging Guided Multimodal Therapy
inferred← citeshttps://doi.org/10.1002/9781119863564.ch5openalex-snapshot
Parathyroid Gland and Bone Therapies
inferred← citeshttps://doi.org/10.1002/adma.202505951openalex-snapshot
Dual Targeting of m 7 G tRNA Modification and Histone Acetylation using Carrier‐Free Nano‐Epidrugs to Evoke Osteosarcoma Chemosensitization
inferred← citeshttps://doi.org/10.1002/advs.202206779openalex-snapshot
Tantalum–Zirconium Co‐Doped Metal–Organic Frameworks Sequentially Sensitize Radio–Radiodynamic–Immunotherapy for Metastatic Osteosarcoma
inferred← citeshttps://doi.org/10.1002/advs.202513310openalex-snapshot
ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling
inferred← citeshttps://doi.org/10.1002/btm2.10654openalex-snapshot
Spatiotemporal evolutionary process of osteosarcoma immune microenvironment remodeling and C1QBP‐driven drug resistance deciphered through single‐cell multi‐dimensional analysis
inferred← citeshttps://doi.org/10.1002/cam4.70391openalex-snapshot
Biological Activity of Biomarkers Associated With Metastasis in Osteosarcoma Cell Lines
inferred← citeshttps://doi.org/10.1002/eji.202048980openalex-snapshot
Epigenetic Regulations in Autoimmunity and Cancer: from Basic Science to Translational Medicine
inferred← citeshttps://doi.org/10.1002/ijc.34841openalex-snapshot
Augmented drug resistance of osteosarcoma cells within decalcified bone matrix scaffold: The role of glutamine metabolism
inferred← citeshttps://doi.org/10.1002/jbt.23846openalex-snapshot
Circ_0004674 regulation of glycolysis and proliferation mechanism of osteosarcoma through miR‐140‐3p/TCF4 pathway
inferred← citeshttps://doi.org/10.1002/jcp.70100openalex-snapshot
Bidirectional Regulatory Mechanisms of Disulfidptosis Govern Precision Targeting in Degenerative Bone Diseases and Osteosarcoma
inferred← citeshttps://doi.org/10.1002/jev2.70130openalex-snapshot
124 I‐labelled BMSC‐Derived Extracellular Vesicles Deliver CRISPR/Cas9 Ribonucleoproteins With a GFP‐Reporter System to Inhibit Osteosarcoma Proliferation and Metastasis
inferred← citeshttps://doi.org/10.1002/jor.70232openalex-snapshot
METTL14‐Mediated RPL13A Expression Regulates Apoptosis and Invasion of Osteosarcoma via the PTEN/PI3K/AKT Signaling Pathway
inferred← citeshttps://doi.org/10.1002/mco2.292openalex-snapshot
Post‐translational modifications of histones: Mechanisms, biological functions, and therapeutic targets
inferred← citeshttps://doi.org/10.1002/smll.202204852openalex-snapshot
Collaborative Design of MgO/FeOx Nanosheets on Titanium: Combining Therapy with Regeneration
inferred← citeshttps://doi.org/10.1002/smtd.202400436openalex-snapshot
Bone and Joint‐on‐Chip Platforms: Construction Strategies and Applications
inferred← citeshttps://doi.org/10.1002/tox.24325openalex-snapshot
Deciphering the role of lipid metabolism and acetylation in osteosarcoma: A comprehensive molecular analysis
inferred← citeshttps://doi.org/10.1007/s00210-023-02903-wopenalex-snapshot
RETRACTED ARTICLE: Micafungin exerts antitumor effect on breast cancer and osteosarcoma through preventing EMT in tumor cells in an USP7/AKT/GSK-3β pathway-dependent manner
inferred← citeshttps://doi.org/10.1007/s10142-023-01197-8openalex-snapshot
CircUSP48 promotes malignant behavior by regulating CYR61 via miR-365 in osteosarcoma
inferred← citeshttps://doi.org/10.1007/s10528-026-11404-3openalex-snapshot
HILPDA, Regulated by WTAP in an m6A-Dependent Manner, Enhances Osteosarcoma Development by Inhibiting Ferroptosis and Promoting Glycolysis
inferred← citeshttps://doi.org/10.1007/s10555-026-10373-8openalex-snapshot
Decoding osteosarcoma mechanobiology: PIEZO channels in tumor progression, immune remodeling, and pain
inferred← citeshttps://doi.org/10.1007/s10616-025-00792-wopenalex-snapshot
Erianin induces apoptosis of osteosarcoma cells through ferroptosis signaling pathway, and inhibits proliferation and migration of osteosarcoma cells
inferred← citeshttps://doi.org/10.1007/s11010-026-05552-8openalex-snapshot
SENP1 regulates the malignant activities of osteosarcoma cells and antitumor immunity via the cGAS-STING signaling
inferred← citeshttps://doi.org/10.1007/s11010-026-05578-yopenalex-snapshot
Single-cell transcriptomics reveals glycolytic heterogeneity and identifies STC2 as a key regulator of metabolic reprogramming in osteosarcoma
inferred← citeshttps://doi.org/10.1007/s11596-026-00235-3openalex-snapshot
Matrix Competence Failure in Osteoporosis: Mechanosensing, Osteoimmune Crosstalk, and Fragility Beyond Bone Mineral Density
inferred← citeshttps://doi.org/10.1007/s11914-023-00803-9openalex-snapshot
Advances in Osteosarcoma
inferred← citeshttps://doi.org/10.1007/s12032-025-03097-2openalex-snapshot
BMP-9 promotes the expression of PD-L1 in osteosarcoma cells through FOXO1
inferred← citeshttps://doi.org/10.1007/s12602-026-11229-xopenalex-snapshot
Epinecidin-1 Induces Distinct Oncosis and Pyroptosis Responses in Osteosarcoma Cells and Enhances Methotrexate-associated Cytotoxicity
inferred← citeshttps://doi.org/10.1007/s12672-024-01280-xopenalex-snapshot
Unraveling the role of bisphenol A in osteosarcoma biology: insights into prognosis and immune microenvironment modulation
inferred← citeshttps://doi.org/10.1007/s12672-024-01461-8openalex-snapshot
Integrated immunogenomic analyses of single-cell and bulk profiling construct a T cell-related signature for predicting prognosis and treatment response in osteosarcoma
inferred← citeshttps://doi.org/10.1007/s12672-026-04913-5openalex-snapshot
miR-155-5p promotes osteosarcoma progression and cisplatin resistance by targeting the SOCS1/STAT1/c-Fos signaling axis
inferred← citeshttps://doi.org/10.1007/s12672-026-05035-8openalex-snapshot
LncRNA MCM3AP-AS1 is a potential prognostic marker for osteosarcoma and promotes its development by targeting miR-205-5p
inferred← citeshttps://doi.org/10.1007/s13353-024-00872-1openalex-snapshot
Discovery of core genes and intercellular communication role in osteosarcoma
inferred← citeshttps://doi.org/10.1007/s13402-026-01226-1openalex-snapshot
Machine learning–based integrative analysis identifies CXCL13-driven tertiary lymphoid structures as favorable immune and prognostic features in osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.actbio.2025.04.057openalex-snapshot
Insights into the osteosarcoma microenvironment: Multiscale analysis of structural and mineral heterogeneity
inferred← citeshttps://doi.org/10.1016/j.bbrep.2026.102732openalex-snapshot
LNP-mediated silencing of oncogenic lncRNA PVT1 enhances chemotherapeutic efficacy in osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.bcp.2025.117093openalex-snapshot
Arsenic compounds in cancer therapy: mechanistic insights and antitumor activity
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2025.123263openalex-snapshot
Implant derived high local concentration of magnesium inhibits tumorigenicity of osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.114771openalex-snapshot
The promising roles of exosomal microRNAs in osteosarcoma: A new insight into the clinical therapy
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.117094openalex-snapshot
Penfluridol regulates p62 / Keap1 / Nrf2 signaling pathway to induce ferroptosis in osteosarcoma cells
inferred← citeshttps://doi.org/10.1016/j.biopha.2025.118471openalex-snapshot
Three-dimensional preclinical models for Osteosarcoma: Advances and translational prospects
inferred← citeshttps://doi.org/10.1016/j.bone.2024.117333openalex-snapshot
The functions and clinical implications of hsa_circ_0032462-miR-488-3p-SLC7A1 axis in human osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.bone.2026.117832openalex-snapshot
NSUN6-mediated m5C RNA methylation aggravate osteosarcoma progression through promoting PKP2 mRNA stability and expression
inferred← citeshttps://doi.org/10.1016/j.bone.2026.118070openalex-snapshot
ZCCHC4-mediated m6A methylation regulates the UHRF1/CDO1 axis to inhibit ferroptosis and promote osteosarcoma malignant progression
inferred← citeshttps://doi.org/10.1016/j.canlet.2025.218121openalex-snapshot
CPE/HYOU1 axis-activated Hippo-YAP signaling pathway suppresses PANoptosis to facilitate osteosarcoma progression
inferred← citeshttps://doi.org/10.1016/j.cellsig.2023.110858openalex-snapshot
CircTNPO1 promotes the tumorigenesis of osteosarcoma by sequestering miR-578 to upregulate WNT5A expression
inferred← citeshttps://doi.org/10.1016/j.cellsig.2025.111855openalex-snapshot
STUB1-mediated ubiquitination of SLC25A10 regulates mitochondrial function and drives osteosarcoma progression: A novel therapeutic target
inferred← citeshttps://doi.org/10.1016/j.cellsig.2025.112077openalex-snapshot
ABLIM1 promotes the proliferation, migration and invasion of osteosarcoma through DCC mediated activation of PI3K/AKT signaling pathway
inferred← citeshttps://doi.org/10.1016/j.cellsig.2026.112733openalex-snapshot
PFKP promotes oncogenesis in osteosarcoma through PI3K/HIF-1α pathway-mediated H3K18la modification
inferred← citeshttps://doi.org/10.1016/j.ejcb.2024.151469openalex-snapshot
GsMTx-4 venom toxin antagonizes biophysical modulation of metastatic traits in human osteosarcoma cells
inferred← citeshttps://doi.org/10.1016/j.ejpb.2026.115132openalex-snapshot
Lipoxin A4 (LXA4) versus Nanolipoxin A4 (Nano-LXA4) for osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.gendis.2026.102514openalex-snapshot
The fragility and dual biological functions of PARK2 in neuroinflammation and tumorigenesis
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e27630openalex-snapshot
Immunogenic cell death related mRNAs associated signature to predict immunotherapeutic response in osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e31971openalex-snapshot
Allicin affects immunoreactivity of osteosarcoma cells through lncRNA CBR3-AS1
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e32231openalex-snapshot
Identification of immune-related tumor antigens and immune subtypes in osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2024.123865openalex-snapshot
Mitochondria targeted biomimetic platform for chemo/photodynamic combination therapy against osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.111226openalex-snapshot
In vitro and in vivo killing effects of methionine enkephalin on osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.113759openalex-snapshot
m6A methylation modification: Potential pathways to suppress osteosarcoma metastasis
inferred← citeshttps://doi.org/10.1016/j.intimp.2025.115482openalex-snapshot
RNF207 promotes the proliferation, migration and invasion of osteosarcoma through KCNQ1 mediated activation of ERK/MEK signaling pathway
inferred← citeshttps://doi.org/10.1016/j.jbo.2024.100604openalex-snapshot
Single-cell transcriptional profiling in osteosarcoma and the effect of neoadjuvant chemotherapy on the tumor microenvironment
inferred← citeshttps://doi.org/10.1016/j.jbo.2025.100692openalex-snapshot
Glutathione peroxidase 7 knockdown inhibits growth, invasion, and migration while enhancing oxidative stress and ferroptosis in osteosarcoma cells
inferred← citeshttps://doi.org/10.1016/j.jbo.2025.100701openalex-snapshot
Yin Yang 1 protein-activated N-acetyltransferase 10 drives cell malignant progression of osteosarcoma through ac4C acetylation of integrin β3
inferred← citeshttps://doi.org/10.1016/j.jbo.2026.100743openalex-snapshot
Efferocytosis-associated transcriptomic patterns characterize prognosis and immune landscape in osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.jbo.2026.100787openalex-snapshot
Integrative machine learning and multi-omics identify a centromere gene signature and validate B3GALT4 as a tumor suppressor in osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.jma.2025.101975openalex-snapshot
NIR/TME-responsive release of zoledronic acid-loaded LDHs on ZE21C magnesium alloy with multi-therapy for osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.jos.2024.10.011openalex-snapshot
CD93 aggravates cell proliferation, angiogenesis and immune escape in osteosarcoma through triggering the PI3K/AKT pathway
inferred← citeshttps://doi.org/10.1016/j.jpet.2026.104890openalex-snapshot
Mechanisms by which chromobox homolog 4 regulates angiogenic mimicry and angiogenic activity in osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.jpha.2025.101228openalex-snapshot
ZFP36 promotes ferroptosis and mitochondrial dysfunction and inhibits malignant progression in osteosarcoma by regulating the E2F1/ATF4 axis
inferred← citeshttps://doi.org/10.1016/j.jrras.2026.102338openalex-snapshot
The NR4A1-IRF1 axis suppresses dendritic cell maturation to promote an immunosuppressive microenvironment in osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.lddd.2026.100586openalex-snapshot
ABCG2/PRKCA as key mediators of the gut-bone-axis regulated by gut microbiota metabolites and Tripterygium wilfordii in osteosarcoma: Bioinformatics, machine learning, Mendelian randomization and validation
inferred← citeshttps://doi.org/10.1016/j.matdes.2024.112965openalex-snapshot
Oligopeptide modified ICG/Cisplatin@CaCO3 for targeted osteosarcoma NIR-II imaging guided multimodal therapy
inferred← citeshttps://doi.org/10.1016/j.mcp.2024.101993openalex-snapshot
SQLE promotes osteosarcoma progression via activating TGFβ/SMAD signaling pathway
inferred← citeshttps://doi.org/10.1016/j.microc.2026.117109openalex-snapshot
Medical detection of osteosarcoma biomarkers through machine learning and electrochemical sensors: the macromolecular mechanism of BAG2 and MGA proteins
inferred← citeshttps://doi.org/10.1016/j.molimm.2026.01.014openalex-snapshot
Characterizing two subtypes of osteosarcoma using G2M checkpoint-related genes and revealing its immune landscape
inferred← citeshttps://doi.org/10.1016/j.mtbio.2025.101796openalex-snapshot
A catalase-powered self-oxygen-generating soft nanomotor for photodynamic therapy of osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.mtbio.2025.102455openalex-snapshot
A design-of-experiments strategy for engineering 3D topographical features in osteosarcoma modelling
inferred← citeshttps://doi.org/10.1016/j.pbiomolbio.2024.10.003openalex-snapshot
m6A methylation regulators and ncRNAs in osteosarcoma: Potential therapeutic strategies
inferred← citeshttps://doi.org/10.1016/j.pbiomolbio.2025.07.001openalex-snapshot
Advances and challenges in the treatment of osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2026.109014openalex-snapshot
Targeting signaling cascades by bioactive phytocompounds in osteosarcoma: A novel therapeutic approach
inferred← citeshttps://doi.org/10.1016/j.phymed.2025.156912openalex-snapshot
Brusatol induced ferroptosis in osteosarcoma cells by modulating the Keap1/Nrf2/SLC7A11 signaling pathway
inferred← citeshttps://doi.org/10.1016/j.prp.2023.154849openalex-snapshot
Versatile function of AMPK signaling in osteosarcoma: An old player with new emerging carcinogenic functions
inferred← citeshttps://doi.org/10.1016/j.prp.2026.156525openalex-snapshot
Pomolic acid suppresses osteosarcoma growth and metastasis through the TNF/NF-κB-autophagy axis
inferred← citeshttps://doi.org/10.1016/j.redox.2024.103328openalex-snapshot
Synergistic induction of ferroptosis by targeting HERC1-NCOA4 axis to enhance the photodynamic sensitivity of osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.tice.2025.103297openalex-snapshot
Microtubule-based cup-like structures appear during microparticle uptake in U2OS cells cultured on different substrate types
inferred← citeshttps://doi.org/10.1016/j.xinn.2026.101307openalex-snapshot
Transformative biomechanics and mechanobiology breakthroughs shaping the future of health and medicine
inferred← citeshttps://doi.org/10.1016/j.yexcr.2025.114490openalex-snapshot
A m6A writer RBM15 enhances the cell malignancy of osteosarcoma by mediating m6A modification of lncRNA THAP9-AS1
inferred← citeshttps://doi.org/10.1016/j.yexcr.2026.115147openalex-snapshot
The bone vicious cycle: How the microenvironment drives osteosarcoma progression
inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.2c00880openalex-snapshot
Targeting Intratibial Osteosarcoma Using Water-Soluble Copolymers Conjugated to Collagen Hybridizing Peptides
inferred← citeshttps://doi.org/10.1021/acsbiomaterials.3c00357openalex-snapshot
Molecular Mechanism Underlying the Action of a Celastrol-Loaded Layered Double Hydroxide-Coated Magnesium Alloy in Osteosarcoma Inhibition and Bone Regeneration
inferred← citeshttps://doi.org/10.1021/acsbiomaterials.6c00437openalex-snapshot
Robinetin Modulates TGF-β/ERK Signaling and Tumor-Associated Phenotype in 3D Osteosarcoma Spheroids
inferred← citeshttps://doi.org/10.1038/s41388-023-02880-7openalex-snapshot
Low expression of ZFP36L1 in osteosarcoma promotes lung metastasis by inhibiting the SDC4-TGF-β signaling feedback loop
inferred← citeshttps://doi.org/10.1038/s41413-023-00265-wopenalex-snapshot
Impairment of rigidity sensing caused by mutant TP53 gain of function in osteosarcoma
inferred← citeshttps://doi.org/10.1038/s41419-025-08106-wopenalex-snapshot
Targeting TIMM23 to overcome osteosarcoma chemoresistance
inferred← citeshttps://doi.org/10.1038/s41419-025-08217-4openalex-snapshot
Downregulation of ZFP36L1 contributes to methotrexate resistance in osteosarcoma through enhanced NHEJ DNA repair mechanisms
inferred← citeshttps://doi.org/10.1038/s41598-023-32195-2openalex-snapshot
Artificial intelligence reveals dysregulation of osteosarcoma and cuproptosis-related biomarkers, PDHA1, CDKN2A and neutrophils
inferred← citeshttps://doi.org/10.1038/s41598-023-49597-xopenalex-snapshot
Network pharmacology-based research on the effect of Radix Astragali on osteosarcoma and the underlying mechanism
inferred← citeshttps://doi.org/10.1038/s41598-025-04440-3openalex-snapshot
LncRNAs regulates cell death in osteosarcoma
inferred← citeshttps://doi.org/10.1038/s41598-025-13324-5openalex-snapshot
Sulfasalazine induces ferroptosis in osteosarcomas by regulating Nrf2/SLC7A11/GPX4 signaling axis
inferred← citeshttps://doi.org/10.1038/s41598-025-15125-2openalex-snapshot
Exosomal LncRNA SCAMP1-AS1 enhances osteosarcoma malignancy by regulating the LKB1-AMPK signaling pathway
inferred← citeshttps://doi.org/10.1038/s41598-025-26524-wopenalex-snapshot
Pulsed electromagnetic field stimulation subtly modulates doxorubicin sensitivity in a spheroid co-culture model of osteosarcoma
inferred← citeshttps://doi.org/10.1038/s41598-025-91869-1openalex-snapshot
Genetically predicted plasma metabolites mediate the causal relationship between gut microbiota and osteosarcoma
inferred← citeshttps://doi.org/10.1038/s41598-025-95173-wopenalex-snapshot
Identification and characterization of mitochondrial autophagy-related genes in osteosarcoma and predicting clinical prognosis
inferred← citeshttps://doi.org/10.1039/d4lc00762jopenalex-snapshot
Bone microphysiological models for biomedical research
inferred← citeshttps://doi.org/10.1039/d6bm00074fopenalex-snapshot
Next-generation hydrogels and strategies to recreate 3D tumour microenvironments for osteosarcoma: from bioprinting to therapeutic testing
inferred← citeshttps://doi.org/10.1039/d6nr02152bopenalex-snapshot
Dual-targeting poly(2-oxazoline)-coated porous silicon nanoparticles for improving osteosarcoma therapy
inferred← citeshttps://doi.org/10.1063/5.0268234openalex-snapshot
Mechanical cues orchestrate monocyte behavior in immune regulation and disease
inferred← citeshttps://doi.org/10.1080/01652176.2025.2567523openalex-snapshot
In vitro characterization of OSA-424 and OSA-55: new canine models for osteosarcoma research
inferred← citeshttps://doi.org/10.1080/03008207.2023.2223289openalex-snapshot
Knockdown of LncRNA DICER1-AS1 arrests the cell cycle, inhibits cell proliferation, and induces cell apoptosis by regulating CDC5L nuclear transfer in osteosarcoma
inferred← citeshttps://doi.org/10.1080/08982104.2023.2262025openalex-snapshot
CB65 and novel CB65 liposomal system suppress MG63 and Saos-2 osteosarcoma cell growth in vitro
inferred← citeshttps://doi.org/10.1080/17435390.2024.2369602openalex-snapshot
Nanoparticles-encapsulated doxorubicin alleviates drug resistance of osteosarcoma via inducing ferroptosis
inferred← citeshttps://doi.org/10.1080/17460441.2026.2642320openalex-snapshot
Recent advances in purpose-built 3D bioprinted cancer models for drug development
inferred← citeshttps://doi.org/10.1089/ten.teb.2023.0106openalex-snapshot
Biomechanical Aspects in Bone Tumor Engineering
inferred← citeshttps://doi.org/10.1093/rb/rbaf087openalex-snapshot
Recent advances in biomaterials for osteosarcoma treatment
inferred← citeshttps://doi.org/10.1096/fj.202401508rropenalex-snapshot
Inhibition of discoidin domain receptor 1 as a new therapeutic strategy for osteosarcoma
inferred← citeshttps://doi.org/10.1097/cad.0000000000001643openalex-snapshot
DEPDC1 affects autophagy-dependent glycolysis levels in human osteosarcoma cells by modulating RAS/ERK signaling through TTK
inferred← citeshttps://doi.org/10.1097/js9.0000000000003946openalex-snapshot
Cancer-associated fibroblast exosomal miR-214-3p regulated by hnRNPA2B1 promotes cisplatin resistance by inhibiting ferroptosis
inferred← citeshttps://doi.org/10.1097/md.0000000000032389openalex-snapshot
Network pharmacology, molecular docking and bioinformatics reveal the mechanism of Tripterygii Wilfordii against Osteosarcoma
inferred← citeshttps://doi.org/10.1097/md.0000000000035957openalex-snapshot
Network pharmacology-based research on the effect of Scutellaria baicalensis on osteosarcoma and the underlying mechanism
inferred← citeshttps://doi.org/10.1097/md.0000000000048632openalex-snapshot
A retrospective study on the efficacy and safety of anlotinib combined with limb salvage therapy for osteosarcoma after chemotherapy failure
inferred← citeshttps://doi.org/10.1101/2025.09.22.677759openalex-snapshot
Substrate elasticity regulates cytoskeletal remodeling and mechanical behavior of U2OS osteosarcoma cells
inferred← citeshttps://doi.org/10.1111/bph.15715openalex-snapshot
Themed issue: ‘New avenues in cancer prevention and treatment’
inferred← citeshttps://doi.org/10.1111/cpr.13344openalex-snapshot
Circ‐CTNNB1 drives aerobic glycolysis and osteosarcoma progression via m6A modification through interacting with RBM15
inferred← citeshttps://doi.org/10.1111/jcmm.18286openalex-snapshot
Inflammasome‐related gene signatures as prognostic biomarkers in osteosarcoma
inferred← citeshttps://doi.org/10.1111/jcmm.70239openalex-snapshot
USP22 Promotes Osteosarcoma Progression by Stabilising β‐Catenin and Upregulating HK2 and Glycolysis
inferred← citeshttps://doi.org/10.1111/jcmm.71111openalex-snapshot
Gene Expression Alterations Associated With Resveratrol‐Induced Antiproliferative Effects and S‐Phase Cell Cycle Arrest in Osteosarcoma Cancer Cells
inferred← citeshttps://doi.org/10.1152/ajpcell.00302.2024openalex-snapshot
The contribution of the novel CLTC-VMP1 fusion gene to autophagy regulation and energy metabolism in cisplatin-resistant osteosarcoma
inferred← citeshttps://doi.org/10.1155/ijcp/9026711openalex-snapshot
Comprehensive Analysis of FBXO43 Expression and Its Prognostic and Therapeutic Implications in Osteosarcoma
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-22-2470openalex-snapshot
First-in-Maintenance Therapy for Localized High-Grade Osteosarcoma: An Open-Label Phase I/II Trial of the Anti–PD-L1 Antibody ZKAB001
inferred← citeshttps://doi.org/10.1158/1541-7786.mcr-25-0687openalex-snapshot
E3 Ubiquitin Ligase ITCH Enhances P53 Ubiquitination-Dependent Degradation and Drives Osteosarcoma Tumorigenesis
inferred← citeshttps://doi.org/10.1159/000545370openalex-snapshot
UBE2K Facilitates Erlotinib Resistance and Induces Epithelial Mesenchymal Transition in Osteosarcoma Cancer Stem-Like Cells via Activating the mTOR Signaling
inferred← citeshttps://doi.org/10.1177/15353702231220670openalex-snapshot
Curcumin induces ferroptosis and apoptosis in osteosarcoma cells by regulating Nrf2/GPX4 signaling pathway
inferred← citeshttps://doi.org/10.1177/20363613241298536openalex-snapshot
Surgical management of a chest wall osteosarcoma with pleural and lung invasion through en-bloc chest resection and complex reconstruction. Case report
inferred← citeshttps://doi.org/10.1177/20417314261454194openalex-snapshot
Mechanical regulation of mesenchymal stem cell osteogenesis, bone matrix homoeostasis, and skeletal pathology
inferred← citeshttps://doi.org/10.1186/s10020-023-00722-6openalex-snapshot
RILP inhibits tumor progression in osteosarcoma via Grb10-mediated inhibition of the PI3K/AKT/mTOR pathway
inferred← citeshttps://doi.org/10.1186/s12263-025-00771-yopenalex-snapshot
Arjunolic acid inhibits Wnt3a-mediated macrophage M2 polarization to suppress osteosarcoma progression
inferred← citeshttps://doi.org/10.1186/s12885-024-12346-yopenalex-snapshot
High expression of SRSF1 facilitates osteosarcoma progression and unveils its potential mechanisms
inferred← citeshttps://doi.org/10.1186/s12885-024-12836-zopenalex-snapshot
ANK1 inhibits malignant progression of osteosarcoma by promoting ferroptosis
inferred← citeshttps://doi.org/10.1186/s12885-025-13722-yopenalex-snapshot
Efficacy and safety of regorafenib in the treatment of bone sarcomas: systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1186/s12906-024-04689-7openalex-snapshot
Tongguanteng injection exerts anti-osteosarcoma effects through the ER stress-associated IRE1/CHOP pathway
inferred← citeshttps://doi.org/10.1186/s12935-025-03761-7openalex-snapshot
LncRNA SPINT1-AS1 enhances the Warburg effect and promotes the progression of osteosarcoma via the miR-135b-5p/PGAM1 axis
inferred← citeshttps://doi.org/10.1186/s12935-025-04087-0openalex-snapshot
Creatine kinase B, a downstream effector of c-Myb, controls migration of osteosarcoma cells via regulation of N-cadherin
inferred← citeshttps://doi.org/10.1186/s12943-024-02161-1openalex-snapshot
Nanoparticles and bone microenvironment: a comprehensive review for malignant bone tumor diagnosis and treatment
inferred← citeshttps://doi.org/10.1186/s12943-025-02365-zopenalex-snapshot
Targeting metastasis in paediatric bone sarcomas
inferred← citeshttps://doi.org/10.1186/s12951-023-01826-1openalex-snapshot
Active targeting schemes for nano-drug delivery systems in osteosarcoma therapeutics
inferred← citeshttps://doi.org/10.1186/s12951-024-02844-3openalex-snapshot
The biomedical applications of nanozymes in orthopaedics based on regulating reactive oxygen species
inferred← citeshttps://doi.org/10.1186/s12967-025-06227-6openalex-snapshot
HMGCL activates autophagy in osteosarcoma through β-HB mediated inhibition of the PI3K/AKT/mTOR signaling pathway
inferred← citeshttps://doi.org/10.1186/s13018-023-04406-zopenalex-snapshot
ARHGAP44-mediated regulation of the p53/C-myc/Cyclin D1 pathway in modulating the malignant biological behavior of osteosarcoma cells
inferred← citeshttps://doi.org/10.1186/s13018-023-04442-9openalex-snapshot
Circadian rhythm-associated lncRNA RP11-414H17.5 as a key therapeutic target in osteosarcoma affects the tumor immune microenvironment and enhances malignancy
inferred← citeshttps://doi.org/10.1186/s13018-023-04502-0openalex-snapshot
m6A-modified circARHGAP12 promotes the aerobic glycolysis of doxorubicin-resistance osteosarcoma by targeting c-Myc
inferred← citeshttps://doi.org/10.1186/s13018-024-05412-5openalex-snapshot
Inhibition of id-1 reduces osteosarcoma growth and metastasis through mediation of snail
inferred← citeshttps://doi.org/10.1186/s13018-025-06148-6openalex-snapshot
PiRNA hsa_pir_018849 promotes the proliferation and invasion of osteosarcoma cells by regulating the stability of CCN5 mRNA
inferred← citeshttps://doi.org/10.1186/s13020-025-01179-xopenalex-snapshot
Explore the potential mechanism of Huachansu injection against osteosarcoma via metabolomics, network pharmacology and bioinformatics
inferred← citeshttps://doi.org/10.1186/s13062-024-00472-3openalex-snapshot
ZNF692 promotes osteosarcoma cell proliferation, migration, and invasion through TNK2-mediated activation of the MEK/ERK pathway
inferred← citeshttps://doi.org/10.1186/s13578-024-01301-wopenalex-snapshot
The roles of OGT and its mechanisms in cancer
inferred← citeshttps://doi.org/10.1186/s40359-026-05047-7openalex-snapshot
What are the predominant factors predicting trend of post-traumatic growth for patients after bone tumour surgery? A longitudinal observational study
inferred← citeshttps://doi.org/10.1186/s41065-025-00588-0openalex-snapshot
DExD-box helicase 39 A, targeted by coumestrol, facilitates the malignant behaviors of osteosarcoma cells
inferred← citeshttps://doi.org/10.12669/pjms.40.4.8536openalex-snapshot
Effects of combined sintilimab and chemotherapy on progression-free survival and overall survival in osteosarcoma patients with metastasis
inferred← citeshttps://doi.org/10.12677/acm.2024.14102823openalex-snapshot
Construction and Validation of a Prognostic Model for Osteosarcoma Based on Disulfide Death Related lncRNA
inferred← citeshttps://doi.org/10.1515/biol-2025-1296openalex-snapshot
Curcumin induces apoptosis in osteosarcoma cells by regulating the glycolytic pathway via the MAPK axis: a mechanistic study
inferred← citeshttps://doi.org/10.21037/atm-22-6011openalex-snapshot
Construction of a novel mRNAsi-related risk model for predicting prognosis and immunotherapy response in osteosarcoma
inferred← citeshttps://doi.org/10.21203/rs.3.rs-2356189/v1openalex-snapshot
CTNNBIP1 Act as A potential Prognostic Biomarker and A Comprehensive Prognostic Analysis in Osteosarcoma
inferred← citeshttps://doi.org/10.21203/rs.3.rs-2356189/v2openalex-snapshot
Wnt Signaling Pathway Related Gene CTNNBIP1 Act as A potential Prognostic Biomarker and A Comprehensive Prognostic Analysis in Osteosarcoma
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3957709/v1openalex-snapshot
Inhibition of discoidin domain receptor 1 (DDR1) as a new therapeutic strategy for osteosarcoma
inferred← citeshttps://doi.org/10.21203/rs.3.rs-4884389/v1openalex-snapshot
The expression and clinical significance of tumor stem cell markers CD34 and CD40 in osteosarcoma tissue
inferred← citeshttps://doi.org/10.21203/rs.3.rs-9483608/v1openalex-snapshot
Identification of paraptosis related genes in osteosarcoma and development of a risk model based on single cell RNA sequencing and bulk RNA sequencing data
inferred← citeshttps://doi.org/10.2147/cmar.s562346openalex-snapshot
Regorafenib-Induced Stress Response Alters the Bioenergetic Profile of Osteosarcoma Cells and Modulates Gene Expression Associated with Metabolic regulation-a Potential Mechanism of Osteosarcoma Treatment-Related Adaptation
inferred← citeshttps://doi.org/10.2147/dddt.s542983openalex-snapshot
YK-4-279 Induces Osteosarcoma Cell Cycle Arrest, DNA Damage Response, and Apoptosis by Regulating the MAPK Cascade
inferred← citeshttps://doi.org/10.2147/ijn.s560865openalex-snapshot
Intelligent Nanomedicine Systems Utilizing Diverse Nanoparticles for Osteosarcoma Therapy: A Review
inferred← citeshttps://doi.org/10.2174/0109298673446767260313082429openalex-snapshot
An In Vitro Laboratory Exploration Revealed the Antitumor Effects of Melittin on Osteosarcoma Cells
inferred← citeshttps://doi.org/10.2174/0113895575398488250831213920openalex-snapshot
The Roles, Mechanisms, and Clinical Significance of Long Non-coding RNA MSC-AS1 in Cancer
inferred← citeshttps://doi.org/10.2174/0118715206343978241223080625openalex-snapshot
Harnessing Therapeutic Potential of Allicin Against Cancer: An Exploratory Review
inferred← citeshttps://doi.org/10.2174/0122103155326378250217105556openalex-snapshot
Exploring the Therapeutic Potential of Dietary Phytoactives in Osteosarcoma Management - A Comprehensive Review
inferred← citeshttps://doi.org/10.2174/1568009623666230815115755openalex-snapshot
C-C Motif Chemokine Ligand 5 (CCL5): A Potential Biomarker and Immunotherapy Target for Osteosarcoma
inferred← citeshttps://doi.org/10.2174/1871520623666230913105845openalex-snapshot
Arctigenin Suppresses the Proliferation and Metastasis, and Induces Apoptosis and Cycle Arrest of Osteosarcoma Cells by inhibiting HMOX1 Expression
inferred← citeshttps://doi.org/10.31083/j.fbl2903120openalex-snapshot
METTL3 Promotes Osteosarcoma Metastasis via an m6A-dependent Epigenetic Activity of CBX4
inferred← citeshttps://doi.org/10.3389/fbioe.2024.1421674openalex-snapshot
Revolutionizing bone defect healing: the power of mesenchymal stem cells as seeds
inferred← citeshttps://doi.org/10.3389/fcell.2023.1125881openalex-snapshot
Ezrin expression in female reproductive tissues: A review of regulation and pathophysiological implications
inferred← citeshttps://doi.org/10.3389/fcell.2023.1201200openalex-snapshot
AnnexinA6: a potential therapeutic target gene for extracellular matrix mineralization
inferred← citeshttps://doi.org/10.3389/fcell.2026.1783487openalex-snapshot
Lamins’ role in osteosarcoma
inferred← citeshttps://doi.org/10.3389/fchem.2024.1386076openalex-snapshot
Magnetic-driven hydrogel microrobots for promoting osteosarcoma chemo-therapy with synthetic lethality strategy
inferred← citeshttps://doi.org/10.3389/fendo.2022.1028031openalex-snapshot
Knowledge atlas and emerging trends on ncRNAs of osteosarcoma: A bibliometric analysis
inferred← citeshttps://doi.org/10.3389/fimmu.2024.1427661openalex-snapshot
A novel prognostic signature related to programmed cell death in osteosarcoma
inferred← citeshttps://doi.org/10.3389/fimmu.2024.1489378openalex-snapshot
circFOXP1: a potential diagnostic and therapeutic target in human diseases
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1647931openalex-snapshot
Immunometabolic regulation of disulfidptosis in orthopedic diseases: mechanistic heterogeneity and therapeutic targets
inferred← citeshttps://doi.org/10.3389/fmolb.2023.1297826openalex-snapshot
Mechano-induced cell metabolism disrupts the oxidative stress homeostasis of SAOS-2 osteosarcoma cells
inferred← citeshttps://doi.org/10.3389/fonc.2022.1031802openalex-snapshot
Circ_0007534 as new emerging target in cancer: Biological functions and molecular interactions
inferred← citeshttps://doi.org/10.3389/fonc.2023.1064815openalex-snapshot
Global scientific trends on matrix metalloproteinase and osteosarcoma: A bibliometric and visualized analysis
inferred← citeshttps://doi.org/10.3389/fonc.2023.1156663openalex-snapshot
Identification and validation of an anoikis-related lncRNA signature to predict prognosis and immune landscape in osteosarcoma
inferred← citeshttps://doi.org/10.3389/fonc.2025.1597750openalex-snapshot
Identification of MAEA protein as a potential target for chemoresistance in osteosarcoma using bioinformatics and proteomic analysis
inferred← citeshttps://doi.org/10.3389/fonc.2025.1614058openalex-snapshot
Integrating network pharmacology and transcriptomics to identify solasonine’s anti-osteosarcoma targets and experimental validation
inferred← citeshttps://doi.org/10.3389/fonc.2025.1702219openalex-snapshot
Decoding the immune microenvironment in osteosarcoma: new insights into checkpoints, vaccines, and CAR-T cells
inferred← citeshttps://doi.org/10.3389/fonc.2026.1770105openalex-snapshot
MRI-based intratumoral and peritumoral radiomics predicting neoadjuvant chemotherapy response in osteosarcoma
inferred← citeshttps://doi.org/10.3389/fphar.2024.1350187openalex-snapshot
Hypoxia inducible factor-1ɑ as a potential therapeutic target for osteosarcoma metastasis
inferred← citeshttps://doi.org/10.3389/fphys.2025.1661054openalex-snapshot
Tissue stiffness heterogeneity in the jaw and temporomandibular joint: its impact on tumor metabolism and considerations for in vitro model development
inferred← citeshttps://doi.org/10.3390/biom12091224openalex-snapshot
Role of WTAP in Cancer: From Mechanisms to the Therapeutic Potential
inferred← citeshttps://doi.org/10.3390/biomedicines10123013openalex-snapshot
CircDOCK1 Regulates miR-186/DNMT3A to Promote Osteosarcoma Progression
inferred← citeshttps://doi.org/10.3390/cancers15030758openalex-snapshot
Anti-Invasive and Anti-Migratory Effects of Ononin on Human Osteosarcoma Cells by Limiting the MMP2/9 and EGFR-Erk1/2 Pathway
inferred← citeshttps://doi.org/10.3390/cimb47110887openalex-snapshot
HMGB1 and Its Signaling Pathway in Osteosarcoma: Current Advances in Targeted Therapy
inferred← citeshttps://doi.org/10.3390/diagnostics13122101openalex-snapshot
Paget’s Disease of the Bone and Lynch Syndrome: An Exceptional Finding
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