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Chromones: Privileged scaffold in anticancer drug discovery
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/9780470187012openalex-snapshot
Chemistry of Heterocyclic Compounds
inferredcites →https://doi.org/10.1002/9780470187012.ch7openalex-snapshot
Naturally Occurring Chromones
inferredcites →https://doi.org/10.1002/anie.201306948openalex-snapshot
Discovery of Inhibitors of the Wnt and Hedgehog Signaling Pathways through the Catalytic Enantioselective Synthesis of an Iridoid‐Inspired Compound Collection
inferredcites →https://doi.org/10.1002/ardp.201200220openalex-snapshot
Synthesis and Biological Evaluation of New Bischromone Derivatives with Antiproliferative Activity
inferredcites →https://doi.org/10.1002/ejoc.201501278openalex-snapshot
One‐Pot Synthesis of Benzopyran‐4‐ones with Cancer Preventive and Therapeutic Potential
inferredcites →https://doi.org/10.1002/jhet.3813openalex-snapshot
Synthesis of furo[3,2‐g]chromones under microwave irradiation and their antitumor activity evaluation
inferredcites →https://doi.org/10.1007/s11243-014-9904-zopenalex-snapshot
Synthesis, characterization and anticancer activity of 3-formylchromone benzoylhydrazone metal complexes
inferredcites →https://doi.org/10.1007/s12272-001-1253-yopenalex-snapshot
A new chromone glycoside from Rhododendron spinuliferum
inferredcites →https://doi.org/10.1016/j.bcp.2012.03.007openalex-snapshot
Discovery of novel A3 adenosine receptor ligands based on chromone scaffold
inferredcites →https://doi.org/10.1016/j.bmc.2014.03.046openalex-snapshot
Bis(4-hydroxy-2H-chromen-2-one): Synthesis and effects on leukemic cell lines proliferation and NF-κB regulation
inferredcites →https://doi.org/10.1016/j.bmcl.2011.03.079openalex-snapshot
Synthesis, structure–activity relationship of novel substituted 4H-chromen-1,2,3,4-tetrahydropyrimidine-5-carboxylates as potential anti-mycobacterial and anticancer agents
inferredcites →https://doi.org/10.1016/j.bmcl.2014.09.057openalex-snapshot
Synthesis and SAR studies of bis-chromenone derivatives for anti-proliferative activity against human cancer cells
inferredcites →https://doi.org/10.1016/j.clinre.2013.06.012openalex-snapshot
In vitro regulation of hepatocellular carcinoma cell viability, apoptosis, invasion, and AEG-1 expression by LY294002
inferredcites →https://doi.org/10.1016/j.ejmech.2006.04.008openalex-snapshot
Synthesis and anticancer activity of lavendustin A derivatives containing arylethenylchromone substituents
inferredcites →https://doi.org/10.1016/j.ejmech.2009.01.034openalex-snapshot
Synthesis of 2-styrylchromones as a novel class of antiproliferative agents targeting carcinoma cells
inferredcites →https://doi.org/10.1016/j.ejmech.2010.02.028openalex-snapshot
Synthesis, anticancer and antioxidant activities of 7-methoxyisoflavanone and 2,3-diarylchromanones
inferredcites →https://doi.org/10.1016/j.ejmech.2011.12.025openalex-snapshot
Antitumor agents 292. Design, synthesis and pharmacological study of S- and O-substituted 7-mercapto- or hydroxy-coumarins and chromones as potent cytotoxic agents
inferredcites →https://doi.org/10.1016/j.ejmech.2012.04.026openalex-snapshot
Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry
inferredcites →https://doi.org/10.1016/j.ejmech.2012.04.028openalex-snapshot
Synthesis and biological activity assays of some new N1-(flavon-7-yl)amidrazone derivatives and related congeners
inferredcites →https://doi.org/10.1016/j.ejmech.2013.09.024openalex-snapshot
Multifunctional tacrine–flavonoid hybrids with cholinergic, β-amyloid-reducing, and metal chelating properties for the treatment of Alzheimer's disease
inferredcites →https://doi.org/10.1016/j.ejmech.2014.03.047openalex-snapshot
Chromones as a privileged scaffold in drug discovery: A review
inferredcites →https://doi.org/10.1016/j.ejmech.2014.05.023openalex-snapshot
Ferrocenyl and dicobalt hexacarbonyl chromones – New organometallics inducing oxidative stress and arresting human cancer cells in G2/M phase
inferredcites →https://doi.org/10.1016/j.ejmech.2014.07.013openalex-snapshot
Flavones: An important scaffold for medicinal chemistry
inferredcites →https://doi.org/10.1016/j.ejmech.2015.01.061openalex-snapshot
Design, synthesis and docking studies of novel thienopyrimidine derivatives bearing chromone moiety as mTOR/PI3Kα inhibitors
inferredcites →https://doi.org/10.1016/j.ejmech.2015.02.048openalex-snapshot
Recent advances of chroman-4-one derivatives: Synthetic approaches and bioactivities
inferredcites →https://doi.org/10.1016/j.ejmech.2015.04.033openalex-snapshot
Synthesis, carbonic anhydrase inhibition and cytotoxic activity of novel chromone-based sulfonamide derivatives
inferredcites →https://doi.org/10.1016/j.ejmech.2015.12.010openalex-snapshot
Flavonoid derivatives as selective ABCC1 modulators: Synthesis and functional characterization
inferredcites →https://doi.org/10.1016/j.jinorgbio.2014.02.014openalex-snapshot
Synthesis, physico-chemical properties and biological analysis of newly obtained copper(II) complexes with pyrazole derivatives
inferredcites →https://doi.org/10.1016/j.jinorgbio.2016.02.020openalex-snapshot
The synthesis, lipophilicity and cytotoxic effects of new ruthenium(II) arene complexes with chromone derivatives
inferredcites →https://doi.org/10.1016/j.jorganchem.2013.05.009openalex-snapshot
Ferrocenylvinyl-flavones: Synthesis, structure, anticancer and antibacterial activity studies
inferredcites →https://doi.org/10.1016/j.molstruc.2021.130502openalex-snapshot
Rational design, synthesis, biological evaluation and molecular docking studies of chromone-pyrimidine derivatives as potent anti-cancer agents
inferredcites →https://doi.org/10.1016/j.poly.2016.01.011openalex-snapshot
Synthesis, crystal structure and biological evaluation of Ni(II) complexes containing 4-chromone-N(4)-substituted thiosemicarbazone ligands
inferredcites →https://doi.org/10.1016/j.tips.2012.08.002openalex-snapshot
Target-based selection of flavonoids for neurodegenerative disorders
inferredcites →https://doi.org/10.1021/acs.jmedchem.6b01720openalex-snapshot
Chromone as a Privileged Scaffold in Drug Discovery: Recent Advances
inferredcites →https://doi.org/10.1021/acsomega.7b00445openalex-snapshot
Metal- and Solvent-Free Approach to Access 3-Se/S-Chromones from the Cyclization of Enaminones in the Presence of Dichalcogenides Catalyzed by KIO3
inferredcites →https://doi.org/10.1021/bc500154copenalex-snapshot
In Vivo Imaging of Multidrug Resistance Using a Third Generation MDR1 Inhibitor
inferredcites →https://doi.org/10.1021/cr400265zopenalex-snapshot
Chromone: A Valid Scaffold in Medicinal Chemistry
inferredcites →https://doi.org/10.1021/jm101249zopenalex-snapshot
Antitumor Agents 286. Design, Synthesis, and Structure−Activity Relationships of 3′R,4′R-Disubstituted-2′,2′-dimethyldihydropyrano[2,3-f]chromone (DSP) Analogues as Potent Chemosensitizers to Overcome Multidrug Resistance
inferredcites →https://doi.org/10.1021/jm201404wopenalex-snapshot
Substituted Chromones as Highly Potent Nontoxic Inhibitors, Specific for the Breast Cancer Resistance Protein
inferredcites →https://doi.org/10.1021/jm201460yopenalex-snapshot
New Tacrine–4-Oxo-4H-chromene Hybrids as Multifunctional Agents for the Treatment of Alzheimer’s Disease, with Cholinergic, Antioxidant, and β-Amyloid-Reducing Properties
inferredcites →https://doi.org/10.1021/jm401649jopenalex-snapshot
Structure–Activity Relationships of Chromone Derivatives toward the Mechanism of Interaction with and Inhibition of Breast Cancer Resistance Protein ABCG2
inferredcites →https://doi.org/10.1021/jm500930hopenalex-snapshot
Chroman-4-one- and Chromone-Based Sirtuin 2 Inhibitors with Antiproliferative Properties in Cancer Cells
inferredcites →https://doi.org/10.1021/jm501026zopenalex-snapshot
Phosphatidylinositol 3-Kinase (PI3K) and Phosphatidylinositol 3-Kinase-Related Kinase (PIKK) Inhibitors: Importance of the Morpholine Ring
inferredcites →https://doi.org/10.1021/jm501690ropenalex-snapshot
New Frontiers in Selective Human MAO-B Inhibitors
inferredcites →https://doi.org/10.1038/leu.2013.245openalex-snapshot
Chemical genomic screening identifies LY294002 as a modulator of glucocorticoid resistance in MLL-rearranged infant ALL
inferredcites →https://doi.org/10.1038/nrc3079openalex-snapshot
The Hedgehog's tale: developing strategies for targeting cancer
inferredcites →https://doi.org/10.1038/s41598-021-90337-wopenalex-snapshot
A novel synthetic microtubule inhibitor exerts antiproliferative effects in multidrug resistant cancer cells and cancer stem cells
inferredcites →https://doi.org/10.1039/c1np00044fopenalex-snapshot
Flavonoids and their glycosides, including anthocyanins
inferredcites →https://doi.org/10.1039/c3md00241aopenalex-snapshot
Novel benzofuran–chromone and –coumarin derivatives: synthesis and biological activity in K562 human leukemia cells
inferredcites →https://doi.org/10.1039/c4cc08376hopenalex-snapshot
Oxidative regioselective amination of chromones exposes potent inhibitors of the hedgehog signaling pathway
inferredcites →https://doi.org/10.1039/c5ra14988fopenalex-snapshot
Navigating in chromone chemical space: discovery of novel and distinct A 3 adenosine receptor ligands
inferredcites →https://doi.org/10.1039/c9nj02650aopenalex-snapshot
NHC-catalyzed green synthesis of functionalized chromones: DFT mechanistic insights and in vitro activities in cancer cells
inferredcites →https://doi.org/10.1042/bj20061489openalex-snapshot
Exploring the specificity of the PI3K family inhibitor LY294002
inferredcites →https://doi.org/10.1046/j.1365-2222.2000.00879.xopenalex-snapshot
The chromones: history, chemistry and clinical development. A tribute to the work of Dr R. E. C. Altounyan
inferredcites →https://doi.org/10.1080/14756366.2020.1740696openalex-snapshot
Antiproliferative chromone derivatives induce K562 cell death through endogenous and exogenous pathways
inferredcites →https://doi.org/10.1080/14786419.2010.482054openalex-snapshot
Flavonoids: chemical properties and analytical methodologies of identification and quantitation in foods and plants
inferredcites →https://doi.org/10.1080/17460441.2018.1494720openalex-snapshot
Challenges with chromone as a privileged scaffold in drug discovery
inferredcites →https://doi.org/10.1111/fcp.12043openalex-snapshot
Phosphatidylinositol 3‐kinases inhibitor LY 294002 potentiates the cytotoxic effects of doxorubicin, vincristine, and etoposide in a panel of cancer cell lines
inferredcites →https://doi.org/10.1517/13543784.9.12.2903openalex-snapshot
Flavopiridol, the first cyclin-dependent kinase inhibitor to enter the clinic: current status
inferredcites →https://doi.org/10.18632/oncotarget.2566openalex-snapshot
MBL-II-141, a chromone derivative, enhances irinotecan (CPT-11) anticancer efficiency in ABCG2-positive xenografts
inferredcites →https://doi.org/10.2174/092986710791111161openalex-snapshot
Flavonoids Influence Epigenetic-Modifying Enzyme Activity: Structure-Function Relationships and the Therapeutic Potential for Cancer
inferredcites →https://doi.org/10.2174/092986711803414359openalex-snapshot
An Update on Natural Occurrence and Biological Activity of Chromones
inferredcites →https://doi.org/10.2174/138527211796367309openalex-snapshot
Structure-Activity Relationships of Flavonoids
inferredcites →https://doi.org/10.2174/138527211796367354openalex-snapshot
Recent Progress in the Synthesis of Flavonoids: From Monomers to Supra-Complex Molecules
inferredcites →https://doi.org/10.2174/1570180812666141111235539openalex-snapshot
Promising Anticancer Drug Candidates Based on the 7-methoxychromone Scaffold: Synthesis and Evaluation of Antiproliferative Activity
inferredcites →https://doi.org/10.2174/1573406411309030003openalex-snapshot
Synthesis, Topoisomerase I Inhibitory and Cytotoxic Activities of Chromone Derivatives
inferredcites →https://doi.org/10.2174/1871520618666180130102259openalex-snapshot
Anticancer Activity Study of Chromone and Coumarin Hybrids using Electrical Impedance Spectroscopy
inferredcites →https://doi.org/10.21873/anticanres.12674openalex-snapshot
Quantitative Structure–Cytotoxicity Relationship of 2-(N-cyclicamino)chromone Derivatives
inferredcites →https://doi.org/10.21873/anticanres.12747openalex-snapshot
Quantitative Structure–Cytotoxicity Relationship of Pyrano[4,3-b]chromones
inferredcites →https://doi.org/10.3390/medicines7090050openalex-snapshot
Development of Newly Synthesized Chromone Derivatives with High Tumor Specificity against Human Oral Squamous Cell Carcinoma
inferredcites →https://doi.org/10.3390/molecules16031956openalex-snapshot
Synthesis of New Visnagen and Khellin Furochromone Pyrimidine Derivatives and Their Anti-Inflammatory and Analgesic Activity
inferredcites →https://doi.org/10.3390/molecules17010191openalex-snapshot
Chromone and Flavonoid Alkaloids: Occurrence and Bioactivity
inferredcites →https://doi.org/10.3390/molecules20011151openalex-snapshot
Synthesis of Chromonylthiazolidines and Their Cytotoxicity to Human Cancer Cell Lines
inferredcites →https://doi.org/10.3390/molecules200611418openalex-snapshot
Synthesis of (E)-2-Styrylchromones and Flavones by Base-Catalyzed Cyclodehydration of the Appropriate β-Diketones Using Water as Solvent
inferredcites →https://doi.org/10.3390/molecules201119647openalex-snapshot
Anticancer and Antibacterial Activity Studies of Gold(I)-Alkynyl Chromones
inferredcites →https://doi.org/10.3892/mmr.2014.2787openalex-snapshot
LY294002 inhibits the malignant phenotype of osteosarcoma cells by modulating the phosphatidylinositol 3-kinase/Akt/fatty acid synthase signaling pathway in vitro
inferredcites →https://doi.org/10.4103/1735-5362.251855openalex-snapshot
Searching for new cytotoxic agents based on chromen-4-one and chromane-2,4-dione scaffolds
inferredcites →https://doi.org/10.7324/japs.2021.110114openalex-snapshot
Synthesis of 2-styrylchromones: In vitro and in silico anticancer activity evaluation
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4773911openalex-extracted
Divergent Synthesis of Chromones and Chromanones from Diketones Using an Agotf/[Si]H System by Switching Hydrosilanes
inferred← citeshttps://doi.org/10.1002/ajoc.202200031openalex-snapshot
Regiospecific C2‐Difluoroalkylation on Chromone via Transition‐Metal‐free Oxidative Decarboxylation of Aryldifluoroacetic acids
inferred← citeshttps://doi.org/10.1002/ajoc.70408openalex-snapshot
Racemic and Stereoselective Phospha ‐Michael Addition of Chromones and Further Oxidation of C2‐Phosphorylated Chromanones
inferred← citeshttps://doi.org/10.1002/ardp.202200106openalex-snapshot
Therapeutic potential of 1,2,3‐triazole hybrids for leukemia treatment
inferred← citeshttps://doi.org/10.1002/ardp.70224openalex-snapshot
Chromones as Nonclassical Inhibitors of Carbonic Anhydrase IX and XII Isoforms: Probing Chromone‐Based Derivatives
inferred← citeshttps://doi.org/10.1002/cbdv.202300251openalex-snapshot
Selective Induction of DNA Damage and Cell Cycle Arrest Mediated by Chromone‐Triazole Dyads Derivatives: Effects on Breast and Prostate Cancer Cells
inferred← citeshttps://doi.org/10.1002/cbdv.202301930openalex-snapshot
Cytotoxicity Activity of Some meso‐Dihydroguaiaretic Acid Derivatives and Mode of Action of the Most Active Compound.
inferred← citeshttps://doi.org/10.1002/chem.202500283openalex-snapshot
Visible‐Light Photocatalysis for Sustainable Chromene Synthesis and Functionalization
inferred← citeshttps://doi.org/10.1002/ddr.22228openalex-snapshot
Exploring chromone‐2‐carboxamide derivatives for triple‐negative breast cancer targeting EGFR, FGFR3, and VEGF pathways: Design, synthesis, and preclinical insights
inferred← citeshttps://doi.org/10.1002/jhet.70156openalex-snapshot
Utility of 3‐Formylchromone in the Synthesis of Polyfunctional Nitrogenous Hybrids: Empowered by Anticancer Efficiency and Molecular Simulations
inferred← citeshttps://doi.org/10.1002/minf.202200088openalex-snapshot
A Scaffold‐based Deep Generative Model Considering Molecular Stereochemical Information
inferred← citeshttps://doi.org/10.1002/slct.202200834openalex-snapshot
Imidazoquinoxaline as a Privileged Fused Pharmacophore in Anticancer Drug Development: A Review of Synthetic Strategies and Medicinal Aspects
inferred← citeshttps://doi.org/10.1002/slct.202202650openalex-snapshot
Silver‐Catalyzed Regioselective Alkylation of Chromones with Carboxylic Acids
inferred← citeshttps://doi.org/10.1002/tcr.202500073openalex-snapshot
Harnessing Chromone as a Versatile Scaffold for Emerging Biological Applications: Recent Advances and Medicinal Insights
inferred← citeshttps://doi.org/10.1007/s00044-023-03063-5openalex-snapshot
Exploring the potential of chromone scaffold compounds in cancer therapy: targeting key kinase pathways
inferred← citeshttps://doi.org/10.1007/s11030-024-11027-zopenalex-snapshot
HFIP-driven Schmidt-type reaction enables chromone-3-carbonitriles and its applications
inferred← citeshttps://doi.org/10.1016/j.bioorg.2025.109150openalex-snapshot
Exploration of chromenone-based ligands as DNA G-quadruplex targets in triple-negative breast cancer
inferred← citeshttps://doi.org/10.1016/j.bmcl.2024.129853openalex-snapshot
Development of chromone-thiazolidine-2,4-dione Knoevenagel conjugates as apoptosis inducing agents
inferred← citeshttps://doi.org/10.1016/j.carbpol.2024.122667openalex-snapshot
Inclusion complexes of novel formyl chromone Schiff bases with β-Cyclodextrin: Synthesis, characterization, DNA binding studies and in-vitro release study
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Synthesis of 3-phosphinyl chromones via in situ iodination mediated C H phosphination and the tunable synthesis of 2-phosphoryl chromanones
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Molecular networking guided metabolomics for mapping the secondary metabolome of six Melaleuca species and their digestive enzymes' inhibitory potential
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Monoamine oxidase B inhibitors based on natural privileged scaffolds: A review of systematically structural modification
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Synergistic effect of cold gas plasma and experimental drug exposure exhibits skin cancer toxicity in vitro and in vivo
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Synthesis of fluorinated 4H-chromen-4-ones from 2-hydroxyacetophenones and in vitro evaluation of their anticancer and antiviral activity
inferred← citeshttps://doi.org/10.1016/j.molliq.2024.124983openalex-snapshot
Anticorrosive evaluation of an environmentally benign chromone-thiazole hybrid with excellent anticancer activity
inferred← citeshttps://doi.org/10.1016/j.molstruc.2023.137006openalex-snapshot
Nucleophilic transformation of 3-substituted-6,8-dimethylchromones with phenylhydrazine under various reaction conditions: Theoretical, spectroscopic characterization and in silico ADME studies
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Design, synthesis, characterization and biological evaluation of 2H-chromene based [1,2-c]pyrazolone derivatives as promising anticancer agents: In silico computational studies
inferred← citeshttps://doi.org/10.1016/j.phytochem.2024.114046openalex-snapshot
Chromones from the endophytic fungus Bipolaris eleusines
inferred← citeshttps://doi.org/10.1016/j.rechem.2022.100697openalex-snapshot
Halogenation followed by deformylation of 3-formylchromones: A novel approaches for synthesis of 3-halochromones with oxone and NaX
inferred← citeshttps://doi.org/10.1016/j.rechem.2023.101175openalex-snapshot
Synthesis and antibacterial activity of pyrano[3,2-g]chromene-4,6-dione derivatives and their molecular docking and DFT calculation studies
inferred← citeshttps://doi.org/10.1016/j.rechem.2025.102601openalex-snapshot
Natural chromones targeting autophagy signalling pathways as potential anticancer interventions: a systematic review
inferred← citeshttps://doi.org/10.1016/j.tet.2022.132780openalex-snapshot
Photoinduced 6π-Electrocyclization of 1,3,5-hexatriene system containing allomaltol fragment: A convenient approach to polycondensed pyrrole derivatives
inferred← citeshttps://doi.org/10.1016/j.tet.2024.134087openalex-snapshot
Divergent synthesis of chromones and chromanones from diketones using an AgOTf/[Si]H system by switching hydrosilanes
inferred← citeshttps://doi.org/10.1021/acs.joc.2c01005openalex-snapshot
Copper-Mediated Cyclization of o -Hydroxyaryl Enaminones with 3-Indoleacetic Acids toward the Synthesis of 3-Indolmethyl-Chromones
inferred← citeshttps://doi.org/10.1021/acs.joc.3c00407openalex-snapshot
One-Pot Synthesis of Chromone-2-carboxylate Scaffold: An Important Pharmacophore with Diverse Biological Properties
inferred← citeshttps://doi.org/10.1021/acs.joc.3c02337openalex-snapshot
Synthesis of Chroman-2,4-diones via Ring-Opening/Ring-Closing Reaction Involving Palladium-Catalyzed Intramolecular Aryloxycarbonylation
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Selective O -Acylation of Ketones with Carboxylic Acids for Enol Esters Synthesis
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The Experimentalist’s Guide to Machine Learning for Small Molecule Design
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Synthesis, molecular docking studies and biological evaluation of N-(4-oxo-2-(trifluoromethyl)-4H-chromen-7-yl) benzamides as potential antioxidant, and anticancer agents
inferred← citeshttps://doi.org/10.1038/s41598-024-59606-2openalex-snapshot
Synthesis, bioactivity assessment, molecular docking and ADMET studies of new chromone congeners exhibiting potent anticancer activity
inferred← citeshttps://doi.org/10.1038/s41598-024-63237-yopenalex-snapshot
Investigating the potential of 6-substituted 3-formyl chromone derivatives as anti-diabetic agents using in silico methods
inferred← citeshttps://doi.org/10.1039/d2ob00126hopenalex-snapshot
Recent advances in transition metal-free annulation toward heterocycle diversity based on the C–N bond cleavage of enaminone platform
inferred← citeshttps://doi.org/10.1039/d2ob01762hopenalex-snapshot
Radical cyclization of alkynyl aryl ketones for the synthesis of 3-seleno-substituted thiochromones and chromones
inferred← citeshttps://doi.org/10.1039/d2ra03475aopenalex-snapshot
Ni II and Co II binary and ternary complexes of 3-formylchromone: spectroscopic characterization, antimicrobial activities, docking and modeling studies
inferred← citeshttps://doi.org/10.1039/d3cc04107gopenalex-snapshot
Visible-light-enabled cascade cross-dehydrogenative-coupling/cyclization to construct α-chromone substituted α-amino acid derivatives
inferred← citeshttps://doi.org/10.1039/d5nj04550aopenalex-snapshot
Copper-catalyzed tandem cyclization via (C–O) arylation and oxidative acylation for the construction of chromeno-fused isoxazole derivatives
inferred← citeshttps://doi.org/10.1039/d5ra08430jopenalex-snapshot
Exploring the chemical reactivity of 2,6-dimethylchromone toward heterocyclic hydrazines and enamines: experimental and theoretical investigations
inferred← citeshttps://doi.org/10.1080/00397911.2022.2051551openalex-snapshot
Novel heteroannulated chromeno[3′,2′:5,6]pyrido[2,3-d][1,2,4]triazolo[4,3-a] pyrimidines and chromeno[3′′,2′′:5′,6′]pyrido[2′,3′:4,5]pyrimido[2,1-c][1,2,4] triazines: Synthesis, characterization and antimicrobial evaluation
inferred← citeshttps://doi.org/10.1080/00397911.2023.2287654openalex-snapshot
Design, synthesis and antimicrobial activity of heteroannulated chromeno[3′,2′:5,6]pyrido[2,3- d ][1,3]thiazolo[3,2- a ]pyrimidines
inferred← citeshttps://doi.org/10.1080/00397911.2025.2463603openalex-snapshot
Ring opening and recyclization reactions with 3-functionalized chromones: Recent synthetic approaches for five, six and seven membered heterocycles
inferred← citeshttps://doi.org/10.1080/10406638.2022.2118334openalex-snapshot
Therapeutic Efficacy of Benzimidazole and Its Analogs: An Update
inferred← citeshttps://doi.org/10.1080/10406638.2022.2158885openalex-snapshot
Recyclization Reactions of 2-Methylchromone-3-Carbonitrile with Active Methylene Nucleophiles: Synthesis and Reactions of 4-Methylchromeno[2,3-b]Pyridines
inferred← citeshttps://doi.org/10.1080/10406638.2023.2172050openalex-snapshot
Novel heteroannulated chromeno[3′,2′:5,6]pyrido[2,3- d ]pyrido[2′,3′: 4,5][1,3]thiazolo[3,2- a ]pyrimidines: synthesis, characterization and antimicrobial evaluation
inferred← citeshttps://doi.org/10.1080/10408347.2022.2094198openalex-snapshot
Analytical Methods for Furanochromone Natural Product, Khellin and Its Inspired Drug Candidates, Amiodarone and Sodium Cromoglycate
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Novel chromone-based thiazolidinone-5-ylidene through hydrazone linker: synthesis, antiproliferative activity, apoptosis induction, cell cycle arrest, autophagy, in silico ADMET and molecular docking studies
inferred← citeshttps://doi.org/10.1080/14786419.2022.2147169openalex-snapshot
Two new chromone derivatives from the rhizosphere soil fungus Ilyonectria robusta
inferred← citeshttps://doi.org/10.1080/17415993.2025.2536599openalex-snapshot
Synthesis, in silico ADMET, and molecular docking studies of novel 3-substituted- 5-[(4-oxo-4 H -chromen-3-yl)methylene]−2-(2-phenylhydrazineylidene)thiazolidin-4-ones inducing apoptosis, autophagy, and cell cycle arrest in breast cancer cell lines
inferred← citeshttps://doi.org/10.1080/17568919.2024.2363668openalex-snapshot
A novel chromone-based as a potential inhibitor of ULK1 that modulates autophagy and induces apoptosis in colon cancer
inferred← citeshttps://doi.org/10.1080/17568919.2026.2718762openalex-snapshot
Chromanone and chromone scaffolds in cancer and metabolic disorders: advances in synthesis, SAR, and developability (2020–2026)
inferred← citeshttps://doi.org/10.1080/19490976.2025.2571433openalex-snapshot
The role of gut mycobiome in responses to cancer immunotherapy
inferred← citeshttps://doi.org/10.1111/cbdd.14166openalex-snapshot
Why are heterocycles so special in medicinal chemistry?
inferred← citeshttps://doi.org/10.1111/cbdd.14639openalex-snapshot
Exploring the Artificial Intelligence and Its Impact in Pharmaceutical Sciences: Insights Toward the Horizons Where Technology Meets Tradition
inferred← citeshttps://doi.org/10.1186/s40538-023-00383-xopenalex-snapshot
Induced secondary metabolites of the beneficial fungus Trichoderma harzianum M10 through OSMAC approach
inferred← citeshttps://doi.org/10.1515/chem-2025-0176openalex-snapshot
Synthesis, biological evaluation, and molecular docking studies of substituted chromone-2-carboxamide derivatives as anti-breast cancer agents
inferred← citeshttps://doi.org/10.17721/fujcv11i2p95-116openalex-snapshot
Chromones Modified with 7-Membered Heterocycles: Synthesis and Biological Activity
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3257298/v1openalex-snapshot
Investigating the Potential of 6-Substituted 3-Formyl Chromone Derivatives as Anti-Diabetic Agents Using DFT, Molecular Docking and Molecular Dynamics Methods
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3706913/v1openalex-snapshot
A Simple and New Chromone Congeners Promote Anticancer Activity: Synthesis, Bioactivity Assessment and molecular docking study with ADME profile
inferred← citeshttps://doi.org/10.2174/0115734064293848240408085039openalex-snapshot
Synthesis, Molecular Docking Studies and Biological Evaluation of Thiazolyl Hydrazone Derivatives of Chromone-3-carbaldehyde as Potent Anti-Oxidant and Anti-Inflammatory Agents
inferred← citeshttps://doi.org/10.2174/0118715206341087241029064945openalex-snapshot
Synthesis of Chromene-linked Bis-indole Derivatives as Selective Tumor-associated Carbonic Anhydrase IX Inhibitors
inferred← citeshttps://doi.org/10.2174/1568026622666220415225334openalex-snapshot
1,2,3-Triazole Derivatives with Anti-breast Cancer Potential
inferred← citeshttps://doi.org/10.2174/1570180820666230111155456openalex-snapshot
Synthesis, Molecular Docking, and Anticancer Activity of N-Heteroaryl Substituted Flavon Derivatives
inferred← citeshttps://doi.org/10.22038/ijbms.2022.65377.14387openalex-snapshot
Chromone derivatives suppress neuroinflammation and improve mitochondrial function in the sporadic form of Alzheimer's disease under experimental conditions.
inferred← citeshttps://doi.org/10.3390/cancers14092196openalex-snapshot
Structure–Activity Relationship of Benzofuran Derivatives with Potential Anticancer Activity
inferred← citeshttps://doi.org/10.3390/ijms24097724openalex-snapshot
Chemical and Biological Evaluation of Novel 1H-Chromeno[3,2-c]pyridine Derivatives as MAO Inhibitors Endowed with Potential Anticancer Activity
inferred← citeshttps://doi.org/10.3390/m2127openalex-snapshot
Ethyl 2-(2-((6-Methyl-4-oxo-4H-chromen-3-yl)methylene)hydrazineyl)thiazole-4-carboxylate
inferred← citeshttps://doi.org/10.3390/md22010023openalex-snapshot
OSMAC Method to Assess Impact of Culture Parameters on Metabolomic Diversity and Biological Activity of Marine-Derived Actinobacteria
inferred← citeshttps://doi.org/10.3390/molecules27092636openalex-snapshot
Synthesis, Experimental and Theoretical Study of Azidochromones
inferred← citeshttps://doi.org/10.3390/molecules27092883openalex-snapshot
Acridine Based N-Acylhydrazone Derivatives as Potential Anticancer Agents: Synthesis, Characterization and ctDNA/HSA Spectroscopic Binding Properties
inferred← citeshttps://doi.org/10.3390/molecules27103300openalex-snapshot
Quantitative and Qualitative Analysis of the Anti-Proliferative Potential of the Pyrazole Scaffold in the Design of Anticancer Agents
inferred← citeshttps://doi.org/10.3390/plants14071012openalex-snapshot
Biosynthesis and Its Regulatory Mechanisms of 2-(2-Phenylethyl)chromones in Agarwood
inferred← citeshttps://doi.org/10.6084/m9.figshare.26578346openalex-snapshot
Additional file 1 of Induced secondary metabolites of the beneficial fungus Trichoderma harzianum M10 through OSMAC approach
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