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Regulation of Interferon-Inducible Proteins by Doxorubicin via Interferon γ-Janus Tyrosine Kinase-Signal Transducer and Activator of Transcription Signaling in Tumor Cells
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/(sici)1097-0142(20000201)88:3<577::aid-cncr13>3.0.co;2-vopenalex-snapshot
Prognostic value of intratumoral natural killer cells in gastric carcinoma
inferredcites →https://doi.org/10.1002/ijc.24276openalex-snapshot
Nmi (N‐Myc interactor) inhibits Wnt/β‐catenin signaling and retards tumor growth
inferredcites →https://doi.org/10.1007/s00262-003-0391-xopenalex-snapshot
Doxorubicin induces specific immune functions and cytokine expression in peritoneal cells
inferredcites →https://doi.org/10.1016/s0014-5793(97)01282-9openalex-snapshot
Doxorubicin‐induced apoptosis in human T‐cell leukemia is mediated by caspase‐3 activation in a Fas‐independent way
inferredcites →https://doi.org/10.1016/s0021-9258(17)36621-8openalex-snapshot
Interferon-gamma induces tyrosine phosphorylation of interferon-gamma receptor and regulated association of protein tyrosine kinases, Jak1 and Jak2, with its receptor.
inferredcites →https://doi.org/10.1016/s0092-8674(00)80965-4openalex-snapshot
Functional Association of Nmi with Stat5 and Stat1 in IL-2- and IFN γ-Mediated Signaling
inferredcites →https://doi.org/10.1016/s1016-8478(23)13080-9openalex-snapshot
Aurintricarboxylic Acid Translocates across the Plasma Membrane, Inhibits Protein Tyrosine Phosphatase and Prevents Apoptosis in PC12 Cells
inferredcites →https://doi.org/10.1016/s1016-8478(23)14019-2openalex-snapshot
AG490, a Jak2-specific Inhibitor, Induces Osteoclast Survival by Activating the Akt and ERK Signaling Pathways
inferredcites →https://doi.org/10.1038/sj.bjp.0704955openalex-snapshot
Inhibition of cytokine‐induced JAK‐STAT signalling pathways by an endonuclease inhibitor aurintricarboxylic acid
inferredcites →https://doi.org/10.1038/sj.onc.1203476openalex-snapshot
The role of STATs in transcriptional control and their impact on cellular function
inferredcites →https://doi.org/10.1038/sj.onc.1203480openalex-snapshot
Divergent roles of STAT1 and STAT5 in malignancy as revealed by gene disruptions in mice
inferredcites →https://doi.org/10.1073/pnas.95.13.7556openalex-snapshot
Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice
inferredcites →https://doi.org/10.1073/pnas.95.26.15623openalex-snapshot
Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays
inferredcites →https://doi.org/10.1074/jbc.c100025200openalex-snapshot
Direct Transcriptional Activation of Human Caspase-1 by Tumor Suppressor p53
inferredcites →https://doi.org/10.1074/jbc.m003177200openalex-snapshot
Interferon-α Induces Nmi-IFP35 Heterodimeric Complex Formation That Is Affected by the Phosphorylation of IFP35
inferredcites →https://doi.org/10.1089/jir.1988.8.263openalex-snapshot
Enhanced Antitumor Efficacy of Adriamycin in Combination with Interferon-γ: Effects on Macrophages
inferredcites →https://doi.org/10.1089/jir.1998.18.549openalex-snapshot
Studies of IFN-Induced Transcriptional Activation Uncover the Jak-Stat Pathway
inferredcites →https://doi.org/10.1124/mol.62.1.90openalex-snapshot
Aurintricarboxylic Acid Protects against Cell Death Caused by Lipopolysaccharide in Macrophages by Decreasing Inducible Nitric-Oxide Synthase Induction via IκB Kinase, Extracellular Signal-Regulated Kinase, and p38 Mitogen-Activated Protein Kinase Inhibition
inferredcites →https://doi.org/10.1124/pr.56.2.6openalex-snapshot
Anthracyclines: Molecular Advances and Pharmacologic Developments in Antitumor Activity and Cardiotoxicity
inferredcites →https://doi.org/10.1126/science.277.5332.1630openalex-snapshot
STATs and Gene Regulation
inferredcites →https://doi.org/10.1146/annurev.immunol.16.1.293openalex-snapshot
JAKS AND STATS: Biological Implications
inferredcites →https://doi.org/10.1158/1078-0432.ccr-06-2894openalex-snapshot
Doxorubicin Directs the Accumulation of Interleukin-12–Induced IFNγ into Tumors for Enhancing STAT1–Dependent Antitumor Effect
inferredcites →https://doi.org/10.1172/jci32136openalex-snapshot
Harnessing the immune system to treat cancer
inferredcites →https://doi.org/10.1189/jlb.1206756openalex-snapshot
Caspase-1 inflammasomes in infection and inflammation
inferredcites →https://doi.org/10.1371/journal.pone.0005821openalex-snapshot
STAT1 Pathway Mediates Amplification of Metastatic Potential and Resistance to Therapy
inferredcites →https://doi.org/10.18926/amo/32897openalex-snapshot
STAT proteins in innate immunity during sepsis: lessons from gene knockout mice.
inferredcites →https://doi.org/10.4049/jimmunol.138.2.641openalex-snapshot
Successful treatment of advanced murine renal cell cancer by bicompartmental adoptive chemoimmunotherapy.
inferredcites →https://doi.org/10.4049/jimmunol.162.7.3897openalex-snapshot
JAK3, STAT, and MAPK Signaling Pathways as Novel Molecular Targets for the Tyrphostin AG-490 Regulation of IL-2-Mediated T Cell Response
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4781335openalex-extracted
The Abl1 Tyrosine Kinase and p53 are Key Players in Doxorubicin-Induced Cardiomyopathy and Their Cell Death Signaling Differs in Atrial and Ventricular Cardiomyocytes
inferred← citeshttps://doi.org/10.1002/jmr.2815openalex-snapshot
Binding of anticancer drug adriamycin to parallel G‐quadruplex DNA [d‐(TTAGGGT)]4 comprising human telomeric DNA leads to thermal stabilization: A multiple spectroscopy study
inferred← citeshttps://doi.org/10.1016/j.bbagen.2016.02.011openalex-snapshot
Nemorubicin and doxorubicin bind the G-quadruplex sequences of the human telomeres and of the c-MYC promoter element Pu22
inferred← citeshttps://doi.org/10.1016/j.bbrc.2024.150943openalex-snapshot
Poly(ADP-ribose) polymerase1 (PARP1) and PARP inhibitors: New frontiers in cervical cancer
inferred← citeshttps://doi.org/10.1016/j.bmc.2020.115761openalex-snapshot
Structural basis for stabilization of human telomeric G-quadruplex [d-(TTAGGGT)]4 by anticancer drug epirubicin
inferred← citeshttps://doi.org/10.1016/j.cell.2016.03.025openalex-snapshot
Cell-to-Cell Variation in p53 Dynamics Leads to Fractional Killing
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2018.09.154openalex-snapshot
Binding of anticancer drug daunomycin to parallel G-quadruplex DNA [d-(TTGGGGT)]4 leads to thermal stabilization: A multispectroscopic investigation
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2019.08.109openalex-snapshot
Molecular recognition of 3 + 1 hybrid human telomeric G-quadruplex DNA d-[AGGG(TTAGGG)3] by anticancer drugs epirubicin and adriamycin leads to thermal stabilization
inferred← citeshttps://doi.org/10.1016/j.lfs.2021.119155openalex-snapshot
Toll-like receptor 4: An attractive therapeutic target for acute kidney injury
inferred← citeshttps://doi.org/10.1021/acsomega.9b00331openalex-snapshot
Affinity of Anticancer Drug Daunomycin toward Tetrahymena Telomeric G-Quadruplex DNA D-[GGGG(TTGGGG)3]
inferred← citeshttps://doi.org/10.1038/bjc.2015.398openalex-snapshot
Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer
inferred← citeshttps://doi.org/10.1038/nm.4087openalex-snapshot
Human induced pluripotent stem cell–derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity
inferred← citeshttps://doi.org/10.1038/s41419-021-04229-yopenalex-snapshot
Stat1 confers sensitivity to radiation in cervical cancer cells by controlling Parp1 levels: a new perspective for Parp1 inhibition
inferred← citeshttps://doi.org/10.1039/c6ra06007bopenalex-snapshot
Macrophage-targeted chitosan anchored PLGA nanoparticles bearing doxorubicin and amphotericin B against visceral leishmaniasis
inferred← citeshttps://doi.org/10.1080/07391102.2020.1730969openalex-snapshot
Structural basis for stabilization of human telomeric G-quadruplex [d-(TTAGGGT)]4 by anticancer drug adriamycin
inferred← citeshttps://doi.org/10.1111/bph.12754openalex-snapshot
Coating doxorubicin‐loaded nanocapsules with alginate enhances therapeutic efficacy against L eishmaniain hamsters by inducing T h1‐type immune responses
inferred← citeshttps://doi.org/10.1128/mbio.00368-17openalex-snapshot
Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion
inferred← citeshttps://doi.org/10.1158/0008-5472.can-15-3034openalex-snapshot
Doxorubicin-Induced Systemic Inflammation Is Driven by Upregulation of Toll-Like Receptor TLR4 and Endotoxin Leakage
inferred← citeshttps://doi.org/10.1186/s12967-024-05623-8openalex-snapshot
The Abl1 tyrosine kinase is a key player in doxorubicin-induced cardiomyopathy and its p53/p73 cell death mediated signaling differs in atrial and ventricular cardiomyocytes
inferred← citeshttps://doi.org/10.1371/journal.pone.0183969openalex-snapshot
A systems medicine approach for finding target proteins affecting treatment outcomes in patients with non-Hodgkin lymphoma
inferred← citeshttps://doi.org/10.3109/00365548.2014.989540openalex-snapshot
Tuberculosis reactivation in hepatocellular carcinoma: association with transarterial chemoembolization
inferred← citeshttps://doi.org/10.3390/biom10040643openalex-snapshot
Sequential Interferon β-Cisplatin Treatment Enhances the Surface Exposure of Calreticulin in Cancer Cells via an Interferon Regulatory Factor 1-Dependent Manner
inferred← citeshttps://doi.org/10.3390/molecules23092266openalex-snapshot
Molecular Recognition of Parallel G-quadruplex [d-(TTGGGGT)]4 Containing Tetrahymena Telomeric DNA Sequence by Anticancer Drug Daunomycin: NMR-Based Structure and Thermal Stability
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