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Small Molecule Inhibitors of ERCC1-XPF Protein-Protein Interaction Synergize Alkylating Agents in Cancer Cells
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Downregulation of XPF–ERCC1 enhances cisplatin efficacy in cancer cells☆
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Characterization of an inhibitory dynamic pharmacophore for the ERCC1–XPA interaction using a combined molecular dynamics and virtual screening approach
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The Structure of the Human ERCC1/XPF Interaction Domains Reveals a Complementary Role for the Two Proteins in Nucleotide Excision Repair
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Repair of DNA interstrand crosslinks: molecular mechanisms and clinical relevance
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Biosensor Analysis of the Interaction between Immobilized Human Serum Albumin and Drug Compounds for Prediction of Human Serum Albumin Binding Levels
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Molecular mechanisms of cisplatin resistance
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Structural basis for the recruitment of ERCC1‐XPF to nucleotide excision repair complexes by XPA
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High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs
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PDB2PQR: expanding and upgrading automated preparation of biomolecular structures for molecular simulations
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DNA repair endonuclease ERCC1-XPF as a novel therapeutic target to overcome chemoresistance in cancer therapy
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The Structure-Specific Endonuclease Ercc1-Xpf Is Required To Resolve DNA Interstrand Cross-Link-Induced Double-Strand Breaks
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Oncogenic H-Ras Up-Regulates Expression of ERCC1 to Protect Cells from Platinum-Based Anticancer Agents
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Regulation of Excision Repair Cross-Complementation Group 1 by Snail Contributes to Cisplatin Resistance in Head and Neck Cancer
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Cisplatin sensitivity of testis tumour cells is due to deficiency in interstrand-crosslink repair and low ERCC1-XPF expression
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Scalable Molecular Dynamics with NAMD
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Excision Repair Cross-Complementation Group 1 (ERCC1) Status and Lung Cancer Outcomes: A Meta-Analysis of Published Studies and Recommendations
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Virtual Screening and Biological Evaluation of Inhibitors Targeting the XPA-ERCC1 Interaction
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Catechols and 3-hydroxypyridones as inhibitors of the DNA repair complex ERCC1-XPF
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Sclareol ameliorated ERCC1-mediated cisplatin resistance in A549 human lung adenocarcinoma cells and a murine xenograft tumor model by suppressing AKT-GSK3β-AP1/Snail and JNK-AP1 pathways
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