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Inactivation of thermogenic UCP1 as a historical contingency in multiple placental mammal clades

https://doi.org/10.1126/sciadv.1602878
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Chiroptera
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Definitive fossil evidence for the extant avian radiation in the Cretaceous
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Three new Jurassic euharamiyidan species reinforce early divergence of mammals
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Brown fat in a protoendothermic mammal fuels eutherian evolution
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Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals
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Microbat paraphyly and the convergent evolution of a key innovation in Old World rhinolophoid microbats
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Cranial remains of an Eocene tarsier
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Revised age estimates for the later Paleogene mammal faunas of Egypt and Oman
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New Paleocene skeletons and the relationship of plesiadapiforms to crown-clade primates
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Patterns of damage in genomic DNA sequences from a Neandertal
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Cosmogenic nuclide dating of Sahelanthropus tchadensis and Australopithecus bahrelghazali : Mio-Pliocene hominids from Chad
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The oldest Asian record of Anthropoidea
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Paleocene emergence of elephant relatives and the rapid radiation of African ungulates
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Climate directly influences Eocene mammal faunal dynamics in North America
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New perspectives on anthropoid origins
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Integrated fossil and molecular data reconstruct bat echolocation
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Resolution of ray-finned fish phylogeny and timing of diversification
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Complete mitochondrial genome sequence of a Middle Pleistocene cave bear reconstructed from ultrashort DNA fragments
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A new Eocene archaeocete (Mammalia, Cetacea) from India and the time of origin of whales
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Uncoupling Protein 1 and Sarcolipin Are Required to Maintain Optimal Thermogenesis, and Loss of Both Systems Compromises Survival of Mice under Cold Stress
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Adelobasileusfrom the Upper Triassic of West Texas: the oldest mammal
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Fossil Sirenia of the West Atlantic and Caribbean region. xi.Callistosiren boriquensis, gen. et sp. nov.
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The readaptation of Eocene sirenians to life in water
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Inferring Speciation Times under an Episodic Molecular Clock
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Estimating a Binary Character's Effect on Speciation and Extinction
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A primitive hyracoid (Mammalia, Paenungulata) from the early Priabonian (Late Eocene) of Egypt
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Quality control and preprocessing of metagenomic datasets
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Easyfig: a genome comparison visualizer
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Paleontological Evidence to Date the Tree of Life
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PAML 4: Phylogenetic Analysis by Maximum Likelihood
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Origin and Ascendancy of a Chimeric Fusion Gene: The / -Globin Gene of Paenungulate Mammals
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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
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Analysis of canonical and non-canonical splice sites in mammalian genomes
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MUSCLE: multiple sequence alignment with high accuracy and high throughput
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Calibrating And Constraining Molecular Clocks
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Model Inadequacy and Mistaken Inferences of Trait-Dependent Speciation
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Testing for Depéret's Rule (Body Size Increase) in Mammals using Combined Extinct and Extant Data
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Only UCP1 can mediate adaptive nonshivering thermogenesis in the cold
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Early Eocene lagomorph (Mammalia) from Western India and the early diversification of Lagomorpha
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Anthropoid versus strepsirhine status of the African Eocene primates Algeripithecus and Azibius : craniodental evidence
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Middle Eocene rodents from Peruvian Amazonia reveal the pattern and timing of caviomorph origins and biogeography
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Fossils and living taxa agree on patterns of body mass evolution: a case study with Afrotheria
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The historical biogeography of Mammalia
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Body mass evolution and diversification within horses (family Equidae)
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THE EVOLUTIONARY HISTORY OF CETACEAN BRAIN AND BODY SIZE
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A NEW SPECIES OF MOERITHERIUM (PROBOSCIDEA, MAMMALIA) FROM THE EOCENE OF ALGERIA: NEW PERSPECTIVES ON THE ANCESTRAL MORPHOTYPE OF THE GENUS
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EVOLUTION OF CLIMATIC ADAPTATION IN HOMEOTHERMS
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Diversitree: comparative phylogenetic analyses of diversification in R
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The evolution of mammal body sizes: responses to C enozoic climate change in N orth A merican mammals
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Brown adipose tissue expresses uncoupling protein 1 in newborn harbor seals (Phoca vitulina)
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Brown adipose tissue in the new‐born calf (Bos taurus).
inferredcites →https://doi.org/10.1126/science.1063902openalex-snapshot
Origin of Whales from Early Artiodactyls: Hands and Feet of Eocene Protocetidae from Pakistan
inferredcites →https://doi.org/10.1126/science.1105113openalex-snapshot
A Molecular Phylogeny for Bats Illuminates Biogeography and the Fossil Record
inferredcites →https://doi.org/10.1126/science.1107808openalex-snapshot
Stem Lagomorpha and the Antiquity of Glires
inferredcites →https://doi.org/10.1126/science.1116030openalex-snapshot
Multiple Causes of High Extinction Risk in Large Mammal Species
inferredcites →https://doi.org/10.1126/science.1116569openalex-snapshot
Basal Anthropoids from Egypt and the Antiquity of Africa's Higher Primate Radiation
inferredcites →https://doi.org/10.1126/science.1194830openalex-snapshot
The Evolution of Maximum Body Size of Terrestrial Mammals
inferredcites →https://doi.org/10.1126/science.1211028openalex-snapshot
Impacts of the Cretaceous Terrestrial Revolution and KPg Extinction on Mammal Diversification
inferredcites →https://doi.org/10.1126/science.1229237openalex-snapshot
The Placental Mammal Ancestor and the Post–K-Pg Radiation of Placentals
inferredcites →https://doi.org/10.1126/science.1234192openalex-snapshot
Evolution of Mammalian Diving Capacity Traced by Myoglobin Net Surface Charge
inferredcites →https://doi.org/10.1127/0078-0421/2012/0020openalex-snapshot
On The Geologic Time Scale
inferredcites →https://doi.org/10.1130/g32701.1openalex-snapshot
Evolution of middle to Late Cretaceous oceans—A 55 m.y. record of Earth's temperature and carbon cycle
inferredcites →https://doi.org/10.1139/f89-273openalex-snapshot
A New Cetacean from the Late Eocene La Meseta Formation Seymour Island, Antarctic Peninsula
inferredcites →https://doi.org/10.1146/annurev-earth-040809-152453openalex-snapshot
The Origin(s) of Whales
inferredcites →https://doi.org/10.1146/annurev.es.24.110193.002343openalex-snapshot
Tertiary Mammal Evolution in the Context of Changing Climates, Vegetation, and Tectonic Events
inferredcites →https://doi.org/10.1152/ajpregu.00021.2009openalex-snapshot
Adaptive thermogenesis and thermal conductance in wild-type and UCP1-KO mice
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Body temperature and rate of O2 consumption in Chinese pangolins
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Metabolism and Insulation of Swine as Bare-Skinned Mammals
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Uncoupling protein 1 in fish uncovers an ancient evolutionary history of mammalian nonshivering thermogenesis
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Brown Adipose Tissue: Function and Physiological Significance
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Thermogenic mechanisms in brown fat.
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A Comparative Survey of Brown Fat in the Neck and Axilla of Mammals at Birth
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The Metabolic Phenotype in Obesity: Fat Mass, Body Fat Distribution, and Adipose Tissue Function
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Molecular evolution of UCP1 and the evolutionary history of mammalian non-shivering thermogenesis
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The brown adipocyte differentiation pathway in birds: An evolutionary road not taken
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Amphicticeps and Amphicynodon (Arctoidea, Carnivora) from Hsanda Gol Formation, Central Mongolia and Phylogeny of Basal Arctoids with Comments on Zoogeography
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Chapter 3
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Chapter 5
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Chapter 7: Phylogeny and Divergence of Basal Glires
inferredcites →https://doi.org/10.1242/jeb.092700openalex-snapshot
Mitochondrial uncoupling prevents cold-induced oxidative stress: a case study using UCP1 knock-out mice
inferredcites →https://doi.org/10.1371/journal.pgen.0020129openalex-snapshot
The Uncoupling Protein 1 Gene (UCP1) Is Disrupted in the Pig Lineage: A Genetic Explanation for Poor Thermoregulation in Piglets
inferredcites →https://doi.org/10.1371/journal.pgen.1000634openalex-snapshot
Molecular Decay of the Tooth Gene Enamelin (ENAM) Mirrors the Loss of Enamel in the Fossil Record of Placental Mammals
inferredcites →https://doi.org/10.1371/journal.pone.0004366openalex-snapshot
New Protocetid Whale from the Middle Eocene of Pakistan: Birth on Land, Precocial Development, and Sexual Dimorphism
inferredcites →https://doi.org/10.1371/journal.pone.0008278openalex-snapshot
Cranial Anatomy of the Earliest Marsupials and the Origin of Opossums
inferredcites →https://doi.org/10.1371/journal.pone.0024146openalex-snapshot
A New Basal Caniform (Mammalia: Carnivora) from the Middle Eocene of North America and Remarks on the Phylogeny of Early Carnivorans
inferredcites →https://doi.org/10.1371/journal.pone.0031294openalex-snapshot
Iterative Evolution of Sympatric Seacow (Dugongidae, Sirenia) Assemblages during the Past ∼26 Million Years
inferredcites →https://doi.org/10.1371/journal.pone.0089739openalex-snapshot
Ocepeia (Middle Paleocene of Morocco): The Oldest Skull of an Afrotherian Mammal
inferredcites →https://doi.org/10.1371/journal.pone.0116734openalex-snapshot
Brown Adipose Tissue in Cetacean Blubber
inferredcites →https://doi.org/10.1371/journal.pone.0157556openalex-snapshot
Convergence of Afrotherian and Laurasiatherian Ungulate-Like Mammals: First Morphological Evidence from the Paleocene of Morocco
inferredcites →https://doi.org/10.14430/arctic852openalex-snapshot
The Ground Sloth, Megalonyx, from Pleistocene Deposits of the Old Crow Basin, Yukon, Canada
inferredcites →https://doi.org/10.1644/1545-1542(2000)081<0914:>2.3.co;2openalex-snapshot
Evolution of Tertiary Mammals of North America. Volume 1: Terrestrial Carnivores, Ungulates, and Ungulatelike Mammals
inferredcites →https://doi.org/10.1666/0094-8373(2004)030<0614:rhpeci>2.0.co;2openalex-snapshot
Reassessing hominoid phylogeny: evaluating congruence in the morphological and temporal data
inferredcites →https://doi.org/10.1671/0272-4634(2005)025[0200:emwteu]2.0.co;2openalex-snapshot
Earliest mammal with transversely expanded upper molar from the Late Triassic (Carnian) Tiki Formation, South Rewa Gondwana Basin, India
inferredcites →https://doi.org/10.1671/039.029.0408openalex-snapshot
Anatomy of the postcranial skeleton of “ Miacis ” uintensis (Mammalia: Carnivoramorpha)
inferredcites →https://doi.org/10.18563/pv.36.1-4.159-233openalex-snapshot
Old world hemiones and new world slender species (Mammalia, Equidae)
inferredcites →https://doi.org/10.18814/epiiugs/2013/v36i3/002openalex-snapshot
The ICS International Chronostratigraphic Chart
inferredcites →https://doi.org/10.2110/pec.95.04.0317openalex-snapshot
Cenozoic South American Land Mammal Ages
inferredcites →https://doi.org/10.2307/1223169openalex-snapshot
Mammal Species of the World: A Taxonomic and Geographic Reference
inferredcites →https://doi.org/10.2307/1374820openalex-snapshot
Acquired Homiothermism in the Pregnant Sloth
inferredcites →https://doi.org/10.2307/1382601openalex-snapshot
Body-Size Diversity and Community Structure of Fossil Hyracoids
inferredcites →https://doi.org/10.24199/j.mmv.2005.62.2openalex-snapshot
Pliocene marine mammals from the Whalers Bluff Formation of Portland, Victoria, Australia
inferredcites →https://doi.org/10.2517/1342-8144-13.3.265openalex-snapshot
New Neogene Hyracoid Specimens from the Peri-Tethys Region and East Africa
inferredcites →https://doi.org/10.26879/424openalex-snapshot
Constraints on the timescale of animal evolutionary history
inferredcites →https://doi.org/10.26879/490openalex-snapshot
Four mammal fossil calibrations: balancing competing palaeontological and molecular considerations
inferredcites →https://doi.org/10.2973/dsdp.proc.29.117.1975openalex-snapshot
Paleotemperature History of the Cenozoic and the Initiation of Antarctic Glaciation: Oxygen and Carbon Isotope Analyses in DSDP Sites 277, 279 and 281
inferredcites →https://doi.org/10.2992/0145-9058(2007)39[97:daaplf]2.0.co;2openalex-snapshot
Dawsonolagus antiquus, A Primitive Lagomorph from the Eocene Arshanto Formation, Nei Mongol, China
inferredcites →https://doi.org/10.3389/fevo.2016.00061openalex-snapshot
Inactivation of Cone-Specific Phototransduction Genes in Rod Monochromatic Cetaceans
inferredcites →https://doi.org/10.4202/app.00136.2014openalex-snapshot
Proboscideans: Shoulder Height, Body Mass and Shape
inferredcites →https://doi.org/10.4202/app.2007.0036openalex-snapshot
Reassessment of the Generic Attribution ofNumidotherium savageiand the Homologies of Lower Incisors in Proboscideans
inferredcites →https://doi.org/10.5281/zenodo.5375879openalex-snapshot
The Xenarthra (Mammalia) of São José de Itaboraí Basin (upper Paleocene, Itaboraian), Rio de Janeiro, Brazil
inferredcites →https://doi.org/10.5962/bhl.title.84425openalex-snapshot
Equidæ of the Oligocene, Miocene and Pliocene of North America, iconographic type revision.
inferredcites →https://doi.org/10.5962/bhl.title.86403openalex-snapshot
Cenozoic mammal horizons of western North America
inferredcites →https://doi.org/10.7312/kiel11918openalex-snapshot
Mammals from the Age of Dinosaurs
inferredcites →https://doi.org/10.7312/leak11870-014openalex-snapshot
8.1. Elephantoidea from Lothagam

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.12688/openreseurope.13795.1zenodo-depositor-declared
Genomic evidence for the parallel regression of melatonin synthesis and signaling pathways in placental mammals
inferred← citeshttps://doi.org/10.12688/openreseurope.13795.2zenodo-depositor-declared
Genomic evidence for the parallel regression of melatonin synthesis and signaling pathways in placental mammals
inferred← citeshttps://doi.org/10.1007/164_2018_116openalex-snapshot
Evolution of UCP1
inferred← citeshttps://doi.org/10.1007/978-1-0716-2087-8_9openalex-snapshot
Activation of UCP1-Independent Ca2+ Cycling Thermogenesis by Wireless Optogenetics
inferred← citeshttps://doi.org/10.1007/978-981-97-4584-5_18openalex-snapshot
Thermal Adaptations in Animals: Genes, Development, and Evolution
inferred← citeshttps://doi.org/10.1007/s00360-021-01362-0openalex-snapshot
Pros and cons for the evidence of adaptive non-shivering thermogenesis in marsupials
inferred← citeshttps://doi.org/10.1007/s00360-023-01512-6openalex-snapshot
Thermoregulation in the wild boar (Sus scrofa)
inferred← citeshttps://doi.org/10.1007/s10863-025-10071-0openalex-snapshot
The mitochondrial uncoupling proteins in early-branching animals: comparative analysis and transcriptional response to temperature in the jellyfish Stomolophus sp.2
inferred← citeshttps://doi.org/10.1007/s13105-019-00708-1openalex-snapshot
The role of autophagy in brown and beige adipose tissue plasticity
inferred← citeshttps://doi.org/10.1016/b978-0-12-818969-6.00020-0openalex-snapshot
Molecular insights into anatomy and physiology
inferred← citeshttps://doi.org/10.1016/b978-0-323-90516-9.00013-0openalex-snapshot
Genetic and molecular adaptations
inferred← citeshttps://doi.org/10.1016/b978-0-323-95219-4.00021-6openalex-snapshot
Endothermy and immunity
inferred← citeshttps://doi.org/10.1016/b978-0-444-63912-7.00009-6openalex-snapshot
Brown adipose tissue as a heat-producing thermoeffector
inferred← citeshttps://doi.org/10.1016/bs.ircmb.2025.10.006openalex-snapshot
Autophagy in adipose tissue thermogenic function
inferred← citeshttps://doi.org/10.1016/j.bpj.2019.11.3385openalex-snapshot
Interaction of a Sarcolipin Pentamer and Monomer with the Sarcoplasmic Reticulum Calcium Pump, SERCA
inferred← citeshttps://doi.org/10.1016/j.carpath.2022.107459openalex-snapshot
The pathobiology of perivascular adipose tissue (PVAT), the fourth layer of the blood vessel wall
inferred← citeshttps://doi.org/10.1016/j.cbpb.2021.110613openalex-snapshot
Comparative functional analyses of UCP1 to unravel evolution, ecophysiology and mechanisms of mammalian thermogenesis
inferred← citeshttps://doi.org/10.1016/j.cmet.2024.11.002openalex-snapshot
Emerging debates and resolutions in brown adipose tissue research
inferred← citeshttps://doi.org/10.1016/j.cmet.2025.03.009openalex-snapshot
Identification of a molecular resistor that controls UCP1-independent Ca2+ cycling thermogenesis in adipose tissue
inferred← citeshttps://doi.org/10.1016/j.cub.2021.02.057openalex-snapshot
Genomic and anatomical comparisons of skin support independent adaptation to life in water by cetaceans and hippos
inferred← citeshttps://doi.org/10.1016/j.isci.2023.108619openalex-snapshot
Summer fades, deer change: Photoperiodic control of cellular seasonal acclimatization of skeletal muscle
inferred← citeshttps://doi.org/10.1016/j.isci.2025.112969openalex-snapshot
In silico analysis of UCP promoters predicts conserved and human specific regulators of adipocyte thermogenesis
inferred← citeshttps://doi.org/10.1016/j.jmb.2020.09.022openalex-snapshot
Emergent Coordination of the CHKB and CPT1B Genes in Eutherian Mammals: Implications for the Origin of Brown Adipose Tissue
inferred← citeshttps://doi.org/10.1016/j.mam.2019.06.006openalex-snapshot
Molecular evolution of thermogenic uncoupling protein 1 and implications for medical intervention of human disease
inferred← citeshttps://doi.org/10.1016/j.mam.2019.07.006openalex-snapshot
Fifty shades of brown: The functions, diverse regulation and evolution of brown adipose tissue
inferred← citeshttps://doi.org/10.1016/j.mce.2021.111402openalex-snapshot
Sex differences in nonshivering thermogenesis in the wild
inferred← citeshttps://doi.org/10.1016/j.neulet.2018.12.027openalex-snapshot
Molecular evolution of uncoupling proteins and implications for brain function
inferred← citeshttps://doi.org/10.1016/j.tree.2020.02.006openalex-snapshot
Is Endothermy an Evolutionary By-Product?
inferred← citeshttps://doi.org/10.1016/j.tree.2020.12.006openalex-snapshot
Integrating Mitochondrial Aerobic Metabolism into Ecology and Evolution
inferred← citeshttps://doi.org/10.1016/j.ygeno.2020.01.023openalex-snapshot
Neofunctionalization of the UCP1 mediated the non-shivering thermogenesis in the evolution of small-sized placental mammals
inferred← citeshttps://doi.org/10.1016/j.ympev.2022.107463openalex-snapshot
Molecular evolutionary analyses of tooth genes support sequential loss of enamel and teeth in baleen whales (Mysticeti)
inferred← citeshttps://doi.org/10.1038/s41467-023-39191-0openalex-snapshot
Dynamic chromatin architecture of the porcine adipose tissues with weight gain and loss
inferred← citeshttps://doi.org/10.1038/s41467-025-64288-zopenalex-snapshot
Cetacean loss of the master adipose tissue regulator β3-adrenergic receptor may underlie their thick blubber and an Oligocene radiation and dispersal
inferred← citeshttps://doi.org/10.1038/s41522-022-00283-2openalex-snapshot
Porcine gut microbiota in mediating host metabolic adaptation to cold stress
inferred← citeshttps://doi.org/10.1038/s41580-021-00350-0openalex-snapshot
The cellular and functional complexity of thermogenic fat
inferred← citeshttps://doi.org/10.1038/s41598-019-42756-zopenalex-snapshot
Muscle nonshivering thermogenesis in a feral mammal
inferred← citeshttps://doi.org/10.1038/s41598-021-04077-yopenalex-snapshot
Recurrent erosion of COA1/MITRAC15 exemplifies conditional gene dispensability in oxidative phosphorylation
inferred← citeshttps://doi.org/10.1038/s41598-021-84762-0openalex-snapshot
Amplification of potential thermogenetic mechanisms in cetacean brains compared to artiodactyl brains
inferred← citeshttps://doi.org/10.1038/s41598-021-97825-zopenalex-snapshot
Atypical for northern ungulates, energy metabolism is lowest during summer in female wild boars (Sus scrofa)
inferred← citeshttps://doi.org/10.1073/pnas.2106080118openalex-snapshot
Comparative genomics provides insights into the aquatic adaptations of mammals
inferred← citeshttps://doi.org/10.1073/pnas.2118431119openalex-snapshot
Evolution of pinniped UCP1 is not linked to aquatic life but to neonatal thermogenesis and body size
inferred← citeshttps://doi.org/10.1073/pnas.2600755123openalex-snapshot
Comparative analysis of naked mole-rat thermogenesis and its potential to maintain euthermia in response to cold
inferred← citeshttps://doi.org/10.1093/gbe/evy243openalex-snapshot
Loss of Enzymes in the Bile Acid Synthesis Pathway Explains Differences in Bile Composition among Mammals
inferred← citeshttps://doi.org/10.1093/jmammal/gyad042openalex-snapshot
Deconstructing the latitudinal diversity gradient of North American mammals by nominal order
inferred← citeshttps://doi.org/10.1093/molbev/msaa212openalex-snapshot
Recapitulating Evolutionary Divergence in a Single Cis -Regulatory Element Is Sufficient to Cause Expression Changes of the Lens Gene Tdrd7
inferred← citeshttps://doi.org/10.1093/molbev/msac230openalex-snapshot
Functional Attenuation of UCP1 as the Potential Mechanism for a Thickened Blubber Layer in Cetaceans
inferred← citeshttps://doi.org/10.1093/molbev/msae075openalex-snapshot
Terrestrial Birth and Body Size Tune UCP1 Functionality in Seals
inferred← citeshttps://doi.org/10.1093/nar/gkaa408openalex-snapshot
PseudoChecker: an integrated online platform for gene inactivation inference
inferred← citeshttps://doi.org/10.1098/rspb.2015.2023openalex-snapshot
Fossils and living taxa agree on patterns of body mass evolution: a case study with Afrotheria
inferred← citeshttps://doi.org/10.1098/rstb.2019.0134openalex-snapshot
Importance of adipocyte browning in the evolution of endothermy
inferred← citeshttps://doi.org/10.1098/rstb.2019.0135openalex-snapshot
Uncoupling of sarcoendoplasmic reticulum calcium ATPase pump activity by sarcolipin as the basis for muscle non-shivering thermogenesis
inferred← citeshttps://doi.org/10.1098/rstb.2019.0136openalex-snapshot
The evolution of mechanisms involved in vertebrate endothermy
inferred← citeshttps://doi.org/10.1101/2020.03.22.002535openalex-snapshot
Recapitulating evolutionary divergence in a single cis -regulatory element is sufficient to cause expression changes of the lens gene Tdrd7
inferred← citeshttps://doi.org/10.1101/2024.05.16.594487openalex-snapshot
Homeodomain transcription factors in adipocyte thermogenesis: insights into the species-specific and conserved regulatory elements of human UCP1
inferred← citeshttps://doi.org/10.1101/688531openalex-snapshot
Horse gluteus is a null-sarcolipin muscle with enhanced sarcoplasmic reticulum calcium transport
inferred← citeshttps://doi.org/10.1111/1749-4877.70047openalex-snapshot
Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model
inferred← citeshttps://doi.org/10.1111/aec.13377openalex-snapshot
Combined effect of ambient temperature and solar radiation on maned sloths' behaviour and detectability
inferred← citeshttps://doi.org/10.1111/apha.13956openalex-snapshot
Novel UCP1 knockout models broaden our understanding of mammalian non‐shivering thermogenesis
inferred← citeshttps://doi.org/10.1111/apha.70109openalex-snapshot
Natural Mutation in Naked Mole‐Rat UCP 1 Refutes Importance of the Histidine Pair Motif for Proton Conductance and Thermogenesis
inferred← citeshttps://doi.org/10.1111/apha.70148openalex-snapshot
Body Temperature Regulation in the Rat by Muscle Tone
inferred← citeshttps://doi.org/10.1111/brv.12822openalex-snapshot
Whole‐body endothermy: ancient, homologous and widespread among the ancestors of mammals, birds and crocodylians
inferred← citeshttps://doi.org/10.1126/sciadv.aaw6671openalex-snapshot
Genes lost during the transition from land to water in cetaceans highlight genomic changes associated with aquatic adaptations
inferred← citeshttps://doi.org/10.1126/sciadv.abl6496openalex-snapshot
Genomic basis for skin phenotype and cold adaptation in the extinct Steller’s sea cow
inferred← citeshttps://doi.org/10.1126/science.adg1947openalex-snapshot
Two-stage evolution of mammalian adipose tissue thermogenesis
inferred← citeshttps://doi.org/10.1134/s2079086423060051openalex-snapshot
Preadaptivity of Noncontractile Thermogenesis in the Evolution of Warm-Bloodedness in Vertebrates
inferred← citeshttps://doi.org/10.1146/annurev-pathol-042220-023633openalex-snapshot
Adipose Tissue Remodeling in Pathophysiology
inferred← citeshttps://doi.org/10.1152/physrev.00024.2024openalex-snapshot
Glycerolipid Cycling in Thermogenesis, Energy Homeostasis, Signaling, and Diseases
inferred← citeshttps://doi.org/10.1210/en.2018-00371openalex-snapshot
Multifaceted Roles of Beige Fat in Energy Homeostasis Beyond UCP1
inferred← citeshttps://doi.org/10.1210/jendso/bvac151openalex-snapshot
Brown to White Fat Transition Overlap With Skeletal Muscle During Development of Larger Mammals: Is it a Coincidence?
inferred← citeshttps://doi.org/10.1242/jeb.162586openalex-snapshot
Nature's fat-burning machine: brown adipose tissue in a hibernating mammal
inferred← citeshttps://doi.org/10.1242/jeb.169425openalex-snapshot
Insights into brown adipose tissue evolution and function from non-model organisms
inferred← citeshttps://doi.org/10.1242/jeb.223974openalex-snapshot
Disruption of thermogenic UCP1 predated the divergence of pigs and peccaries
inferred← citeshttps://doi.org/10.15252/embj.201899071openalex-snapshot
CPEB2‐dependent translation of long 3′‐UTR Ucp1 mRNA promotes thermogenesis in brown adipose tissue
inferred← citeshttps://doi.org/10.22201/fmvz.24486760e.2023.1178openalex-snapshot
Obesidad y plasticidad termogénica del tejido adiposo en perros
inferred← citeshttps://doi.org/10.2337/db19-0308openalex-snapshot
Cellular Origins of Beige Fat Cells Revisited
inferred← citeshttps://doi.org/10.31146/1682-8658-ecg-228-8-7-27openalex-snapshot
Effects of therapeutic factors on brown adipose tissue in order to correct obesity
inferred← citeshttps://doi.org/10.31857/s004213242304004xopenalex-snapshot
Preadaptivity of Non-Contractive Thermogenesis in the Evolution of Warm-Bloodedness in Vertebrates
inferred← citeshttps://doi.org/10.3389/fimmu.2026.1738836openalex-snapshot
Transcriptomic insights into the immune responses of the lung and muscle of non-healthy harbor porpoises (Phocoena phocoena)
inferred← citeshttps://doi.org/10.3389/fped.2020.612279openalex-snapshot
Alternative Polyadenylation and Differential Regulation of Ucp1: Implications for Brown Adipose Tissue Thermogenesis Across Species
inferred← citeshttps://doi.org/10.3389/fphys.2017.00670openalex-snapshot
Evolution of UCP1 Transcriptional Regulatory Elements Across the Mammalian Phylogeny
inferred← citeshttps://doi.org/10.3389/fphys.2017.00889openalex-snapshot
Muscle Non-shivering Thermogenesis and Its Role in the Evolution of Endothermy
inferred← citeshttps://doi.org/10.3389/fphys.2017.00978openalex-snapshot
Commentary: Evolution of UCP1 Transcriptional Regulatory Elements Across the Mammalian Phylogeny
inferred← citeshttps://doi.org/10.3389/fphys.2018.00714openalex-snapshot
Sarcolipin Makes Heat, but Is It Adaptive Thermogenesis?
inferred← citeshttps://doi.org/10.3389/fphys.2021.633058openalex-snapshot
Is Upregulation of Sarcolipin Beneficial or Detrimental to Muscle Function?
inferred← citeshttps://doi.org/10.3390/biology13050284openalex-snapshot
Potential Role of Pig UCP3 in Modulating Adipocyte Browning via the Beta-Adrenergic Receptor Signaling Pathway
inferred← citeshttps://doi.org/10.3390/biom11111705openalex-snapshot
Co-Evolution of Breast Milk Lipid Signaling and Thermogenic Adipose Tissue
inferred← citeshttps://doi.org/10.3390/cells13080709openalex-snapshot
The Role of β3-Adrenergic Receptors in Cold-Induced Beige Adipocyte Production in Pigs
inferred← citeshttps://doi.org/10.3390/ijms24087431openalex-snapshot
Distinct Transcriptional Responses of Skeletal Muscle to Short-Term Cold Exposure in Tibetan Pigs and Bama Pigs
inferred← citeshttps://doi.org/10.3390/ijms26052155openalex-snapshot
Evolution of UCP1 Gene and Its Significance to Temperature Adaptation in Rodents
inferred← citeshttps://doi.org/10.3390/nu15184072openalex-snapshot
Brown Fat and Nutrition: Implications for Nutritional Interventions
inferred← citeshttps://doi.org/10.3390/vetsci7040178openalex-snapshot
Sarcolipin Exhibits Abundant RNA Transcription and Minimal Protein Expression in Horse Gluteal Muscle
inferred← citeshttps://doi.org/10.3410/f.736665351.793567195openalex-snapshot
Faculty Opinions recommendation of Genes lost during the transition from land to water in cetaceans highlight genomic changes associated with aquatic adaptations.
inferred← citeshttps://doi.org/10.5194/aab-65-427-2022openalex-snapshot
Intrinsic challenges of neonatal adaptation in swine
inferred← citeshttps://doi.org/10.70675/6428b749z56ccz4648z8326z85669ba0f33eopenalex-snapshot
Effects of thermophysiology on the evolution of Pseudosuchia (Archosauria) : contributions of paleohistology and isotopic geochemistry using phylogenetic comparative methods
inferred← citeshttps://doi.org/10.7554/elife.38906openalex-snapshot
Recurrent loss of HMGCS2 shows that ketogenesis is not essential for the evolution of large mammalian brains
inferred← citeshttps://doi.org/10.7554/elife.85414openalex-snapshot
Evolution of an extreme hemoglobin phenotype contributed to the sub-Arctic specialization of extinct Steller’s sea cows
inferred← citeshttps://doi.org/10.7717/peerj.19697openalex-snapshot
Molecular evolution of TRPC4 regulatory sequences supports a role in mammalian thermoregulatory adaptation
inferred← citeshttps://doi.org/10.7717/peerj.5600openalex-snapshot
The metabolic response of theBradypussloth to temperature
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