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Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide
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Toll-like receptor function and signaling
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C-terminal LRRs of human Toll-like receptor 3 control receptor dimerization and signal transmission
inferredcites →https://doi.org/10.1038/35099560openalex-snapshot
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
inferredcites →https://doi.org/10.1038/ni1112openalex-snapshot
Toll-like receptor control of the adaptive immune responses
inferredcites →https://doi.org/10.1038/ni886openalex-snapshot
TICAM-1, an adaptor molecule that participates in Toll-like receptor 3–mediated interferon-β induction
inferredcites →https://doi.org/10.1073/pnas.0505077102openalex-snapshot
The molecular structure of the Toll-like receptor 3 ligand-binding domain
inferredcites →https://doi.org/10.1073/pnas.0603245103openalex-snapshot
The dsRNA binding site of human Toll-like receptor 3
inferredcites →https://doi.org/10.1073/pnas.0710779105openalex-snapshot
The TLR3 signaling complex forms by cooperative receptor dimerization
inferredcites →https://doi.org/10.1074/jbc.m507163200openalex-snapshot
Recognition of Double-stranded RNA by Human Toll-like Receptor 3 and Downstream Receptor Signaling Requires Multimerization and an Acidic pH
inferredcites →https://doi.org/10.1074/jbc.m510442200openalex-snapshot
Structural and Functional Analyses of the Human Toll-like Receptor 3
inferredcites →https://doi.org/10.1126/science.1115253openalex-snapshot
Crystal Structure of Human Toll-Like Receptor 3 (TLR3) Ectodomain
inferredcites →https://doi.org/10.1126/science.1139522openalex-snapshot
TLR3 Deficiency in Patients with Herpes Simplex Encephalitis
inferredcites →https://doi.org/10.1146/annurev.biochem.76.060305.151318openalex-snapshot
Structure and Function of Toll Receptors and Their Ligands
inferredcites →https://doi.org/10.4049/jimmunol.171.6.3154openalex-snapshot
Subcellular Localization of Toll-Like Receptor 3 in Human Dendritic Cells
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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DAMPs as mediators of sterile inflammation in aging-related pathologies
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TLRs, future potential therapeutic targets for RA
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The Toll-like receptor 3:dsRNA signaling complex
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The intricate interplay between RNA viruses and NF-κB
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A polar SxxS motif drives assembly of the transmembrane domains of Toll-like receptor 4
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STING recognition of viral dsDNA by nociceptors mediates pain in mice
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Different functional role of domain boundaries of Toll-like receptor 4
inferred← citeshttps://doi.org/10.1016/j.bbrc.2009.06.036openalex-snapshot
Synthetic oligoribonucleotides-containing secondary structures act as agonists of Toll-like receptors 7 and 8
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Toll-like receptors and innate immunity
inferred← citeshttps://doi.org/10.1016/j.bbrc.2012.02.116openalex-snapshot
Endothelial RIG-I activation impairs endothelial function
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Determination of the physiological 2:2 TLR5:flagellin activation stoichiometry revealed by the activity of a fusion receptor
inferred← citeshttps://doi.org/10.1016/j.bbrc.2024.150581openalex-snapshot
Toll-like receptor 21 in Labeo rohita recognizes double-stranded RNA and lipopolysaccharides by engaging the critical motifs in the LRR domain and gets activated against bacterial assaults
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Bifurcation of signalling in human innate immune pathways to NF-kB and IRF family activation
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TLRs and chronic inflammation
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Selectively targeting the toll-like receptor 9 (TLR9) – IRF 7 signaling pathway by polymer blend particles
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Chemical reagents modulate nucleic acid-activated toll-like receptors
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Modulation of the NOD-like receptors NOD1 and NOD2: A chemist’s perspective
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Revitalizing antitumor immunity: Leveraging nucleic acid sensors as therapeutic targets
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Mechanisms of interactions in pattern-recognition of common glycostructures across pectin-derived heteropolysaccharides by Toll-like receptor 4
inferred← citeshttps://doi.org/10.1016/j.ccell.2016.06.021openalex-snapshot
Tumor Exosomal RNAs Promote Lung Pre-metastatic Niche Formation by Activating Alveolar Epithelial TLR3 to Recruit Neutrophils
inferred← citeshttps://doi.org/10.1016/j.cell.2010.01.022openalex-snapshot
Pattern Recognition Receptors and Inflammation
inferred← citeshttps://doi.org/10.1016/j.cell.2011.06.021openalex-snapshot
The Inside-Out Mechanism of Dicers from Budding Yeasts
inferred← citeshttps://doi.org/10.1016/j.cell.2011.09.023openalex-snapshot
Structural Insights into RNA Recognition by RIG-I
inferred← citeshttps://doi.org/10.1016/j.cell.2011.09.027openalex-snapshot
The Powerstroke and Camshaft of the RIG-I Antiviral RNA Detection Machine
inferred← citeshttps://doi.org/10.1016/j.cellimm.2010.05.005openalex-snapshot
Effect of the antimicrobial peptide LL-37 on Toll-like receptors 2-, 3- and 4-triggered expression of IL-6, IL-8 and CXCL10 in human gingival fibroblasts
inferred← citeshttps://doi.org/10.1016/j.cellsig.2014.01.015openalex-snapshot
TLR3 regulates mycobacterial RNA-induced IL-10 production through the PI3K/AKT signaling pathway
inferred← citeshttps://doi.org/10.1016/j.celrep.2026.117748openalex-snapshot
Notch2 signaling instructs viral and bacterial TLR responsiveness in B cells
inferred← citeshttps://doi.org/10.1016/j.cis.2016.02.003openalex-snapshot
A review of immune amplification via ligand clustering by self-assembled liquid–crystalline DNA complexes
inferred← citeshttps://doi.org/10.1016/j.clnves.2025.100018openalex-snapshot
Endogenous double-stranded RNA: Bridging immune activation and cancer therapeutics
inferred← citeshttps://doi.org/10.1016/j.coi.2008.06.002openalex-snapshot
Structures of TLR–ligand complexes
inferred← citeshttps://doi.org/10.1016/j.coi.2008.07.007openalex-snapshot
Accessing the therapeutic potential of immunostimulatory nucleic acids
inferred← citeshttps://doi.org/10.1016/j.coi.2012.10.005openalex-snapshot
Creating diseases to understand what prevents them: genetic analysis of inflammation in the gastrointestinal tract
inferred← citeshttps://doi.org/10.1016/j.coi.2012.11.001openalex-snapshot
TLR3 immunity to infection in mice and humans
inferred← citeshttps://doi.org/10.1016/j.coi.2013.10.009openalex-snapshot
Structures of pattern recognition receptors reveal molecular mechanisms of autoinhibition, ligand recognition and oligomerization
inferred← citeshttps://doi.org/10.1016/j.coi.2016.10.003openalex-snapshot
Nucleic acid-sensing TLRs: trafficking and regulation
inferred← citeshttps://doi.org/10.1016/j.coi.2024.102460openalex-snapshot
Rethinking Toll-like receptor signalling
inferred← citeshttps://doi.org/10.1016/j.crstbi.2023.100097openalex-snapshot
Structural modelling and dynamics of full-length of TLR10 sheds light on possible modes of dimerization, ligand binding and mechanism of action
inferred← citeshttps://doi.org/10.1016/j.csbj.2022.08.001openalex-snapshot
Host-pathogen protein-nucleic acid interactions: A comprehensive review
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2011.02.001openalex-snapshot
Toll-like receptor 3, RIG-I-like receptors and the NLRP3 inflammasome: Key modulators of innate immune responses to double-stranded RNA viruses
inferred← citeshttps://doi.org/10.1016/j.dci.2010.08.001openalex-snapshot
Synthetic double-stranded RNA oligonucleotides are immunostimulatory for chicken spleen cells
inferred← citeshttps://doi.org/10.1016/j.dci.2011.12.004openalex-snapshot
Molecular cloning and characterization of Toll-like receptor 3 in Japanese flounder, Paralichthys olivaceus
inferred← citeshttps://doi.org/10.1016/j.dci.2013.01.001openalex-snapshot
Characterization of white shrimp Litopenaeus vannamei integrin β and its role in immunomodulation by dsRNA-mediated gene silencing
inferred← citeshttps://doi.org/10.1016/j.dci.2013.04.009openalex-snapshot
Unique features of chicken Toll-like receptors
inferred← citeshttps://doi.org/10.1016/j.dci.2015.04.007openalex-snapshot
A member of the Tlr family is involved in dsRNA innate immune response in Paracentrotus lividus sea urchin
inferred← citeshttps://doi.org/10.1016/j.dci.2018.04.022openalex-snapshot
Genomic structure and molecular characterization of Toll-like receptors 1 and 2 from golden pompano Trachinotus ovatus (Linnaeus, 1758) and their expression response to three types of pathogen-associated molecular patterns
inferred← citeshttps://doi.org/10.1016/j.dci.2018.11.012openalex-snapshot
Class A scavenger receptors mediate extracellular dsRNA sensing, leading to downstream antiviral gene expression in a novel American toad cell line, BufoTad
inferred← citeshttps://doi.org/10.1016/j.dci.2020.103990openalex-snapshot
Gene duplication and adaptive evolution of Toll-like receptor genes in birds
inferred← citeshttps://doi.org/10.1016/j.dci.2021.104100openalex-snapshot
Identification and expression analysis of sixteen Toll-like receptor genes, TLR1, TLR2a, TLR2b, TLR3, TLR5M, TLR5S, TLR7−9, TLR13a−c, TLR14, TLR21−23 in mandarin fish Siniperca chuatsi
inferred← citeshttps://doi.org/10.1016/j.dci.2024.105147openalex-snapshot
Natural selection directing molecular evolution in vertebrate viral sensors
inferred← citeshttps://doi.org/10.1016/j.dci.2024.105197openalex-snapshot
TLR7 in channel catfish (Ictalurus punctatus) is expressed in the endolysosome and is stimulated by synthetic ssRNA analogs, imiquimod, and resiquimod.
inferred← citeshttps://doi.org/10.1016/j.drudis.2009.02.009openalex-snapshot
The path to a successful vaccine adjuvant – ‘The long and winding road’
inferred← citeshttps://doi.org/10.1016/j.drudis.2025.104554openalex-snapshot
Advances and challenges in Toll-like receptor-targeted therapy for rheumatoid arthritis
inferred← citeshttps://doi.org/10.1016/j.febslet.2014.08.031openalex-snapshot
Toll‐like receptor 3 transmembrane domain is able to perform various homotypic interactions: An NMR structural study
inferred← citeshttps://doi.org/10.1016/j.fsi.2012.07.010openalex-snapshot
Evolutionary analysis of Antarctic teleost Toll-like receptor 2
inferred← citeshttps://doi.org/10.1016/j.fsi.2015.06.017openalex-snapshot
Structural characterization and evolutionary analysis of fish-specific TLR27
inferred← citeshttps://doi.org/10.1016/j.fsi.2015.08.016openalex-snapshot
Roles of receptor for activated protein kinase C1 for modulating immune responses in white shrimp Litopenaeus vannamei
inferred← citeshttps://doi.org/10.1016/j.fsi.2015.09.005openalex-snapshot
Structural and evolutionary characteristics of fish-specific TLR19
inferred← citeshttps://doi.org/10.1016/j.fsi.2016.01.025openalex-snapshot
Identification and functional characterization of three TLR signaling pathway genes in Cyclina sinensis
inferred← citeshttps://doi.org/10.1016/j.fsi.2016.07.035openalex-snapshot
Identification and expression analysis of IκB and NF-κB genes from Cyclina sinensis
inferred← citeshttps://doi.org/10.1016/j.fsi.2022.09.046openalex-snapshot
Computational analysis and functional characterisation of Tor putitora toll-like receptor 4 with the elucidation of its binding sites for microbial mimicking ligands
inferred← citeshttps://doi.org/10.1016/j.gene.2012.04.007openalex-snapshot
Molecular evolution of vertebrate Toll-like receptors: Evolutionary rate difference between their leucine-rich repeats and their TIR domains
inferred← citeshttps://doi.org/10.1016/j.hlc.2022.02.012openalex-snapshot
Toll-Like Receptor 3 in Cardiovascular Diseases
inferred← citeshttps://doi.org/10.1016/j.humimm.2011.07.307openalex-snapshot
Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk
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