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Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/emmm.201302847openalex-snapshot
The Fragile X Protein binds mRNAs involved in cancer progression and modulates metastasis formation
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GKAP Acts as a Genetic Modulator of NMDAR Signaling to Govern Invasive Tumor Growth
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Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy
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Acquired Resistance to Immune Checkpoint Inhibitors
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Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
inferredcites →https://doi.org/10.1016/j.cell.2011.06.013openalex-snapshot
FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
inferredcites →https://doi.org/10.1016/j.cell.2014.08.035openalex-snapshot
SnapShot: FMRP mRNA Targets and Diseases
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The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity
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Oncogenic Signaling Pathways in The Cancer Genome Atlas
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A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells
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Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles
inferredcites →https://doi.org/10.1016/j.immuni.2019.04.010openalex-snapshot
Intratumoral Activity of the CXCR3 Chemokine System Is Required for the Efficacy of Anti-PD-1 Therapy
inferredcites →https://doi.org/10.1016/j.jcmgh.2020.10.009openalex-snapshot
The Fragile X Mental Retardation Protein Regulates RIPK1 and Colorectal Cancer Resistance to Necroptosis
inferredcites →https://doi.org/10.1016/j.nbd.2005.08.019openalex-snapshot
The generation of a conditional Fmr1 knock out mouse model to study Fmrp function in vivo
inferredcites →https://doi.org/10.1016/j.pbiomolbio.2018.07.001openalex-snapshot
Handling FMRP and its molecular partners: Structural insights into Fragile X Syndrome
inferredcites →https://doi.org/10.1016/j.yexcr.2008.09.020openalex-snapshot
Trafficking and function of the tetraspanin CD63
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FMRP Associates with Polyribosomes as an mRNP, and the I304N Mutation of Severe Fragile X Syndrome Abolishes This Association
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Mechanisms of resistance to immune checkpoint inhibitors
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The fragile X mental retardation protein regulates tumor invasiveness-related pathways in melanoma cells
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Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
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c-MYC: more than just a matter of life and death
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Immunological aspects of cancer chemotherapy
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Post-translational modifications of the Fragile X Mental Retardation Protein in neuronal function and dysfunction
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FMRP modulates the Wnt signalling pathway in glioblastoma
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Chemotherapy induces dynamic immune responses in breast cancers that impact treatment outcome
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Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models
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A reality check of the accelerated approval of immune-checkpoint inhibitors
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RNA-Guided Human Genome Engineering via Cas9
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Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion
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Gene expression analysis in Fmr1KO mice identifies an immunological signature in brain tissue and mGluR5-related signaling in primary neuronal cultures
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inferredcites →https://doi.org/10.18632/oncotarget.4617openalex-snapshot
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inferredcites →https://doi.org/10.18632/oncotarget.6162openalex-snapshot
VE1 immunohistochemistry predictsBRAFV600E mutation status and clinical outcome in colorectal cancer
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Chemokine Receptor CCR5 Antagonist Maraviroc: Medicinal Chemistry and Clinical Applications
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inferredcites →https://doi.org/10.7554/elife.71892openalex-snapshot
FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons
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Crucial biological functions of CCL7 in cancer
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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G‐Quadruplex RNA Based PROTAC Enables Targeted Degradation of RNA Binding Protein FMRP for Tumor Immunotherapy
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G‐Quadruplex RNA Based PROTAC Enables Targeted Degradation of RNA Binding Protein FMRP for Tumor Immunotherapy
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inferred← citeshttps://doi.org/10.1186/s12964-024-01799-0openalex-snapshot
Tumor-associated macrophage-derived itaconic acid contributes to nasopharyngeal carcinoma progression by promoting immune escape via TET2
inferred← citeshttps://doi.org/10.12122/j.issn.1673-4254.2024.05.10openalex-snapshot
[High expression of fragile X mental retardation protein inhibits ferroptosis of colorectal tumor cells by activating the RAS/MAPK signaling pathway].
inferred← citeshttps://doi.org/10.1371/journal.pone.0287062openalex-snapshot
FMRP expression in primary breast tumor cells correlates with recurrence and specific site of metastasis
inferred← citeshttps://doi.org/10.1371/journal.pone.0340222openalex-snapshot
Myeloid Fmr1 deficiency in mice results in reduced serum cholesterol and altered bile pathway gene expression
inferred← citeshttps://doi.org/10.20517/cdr.2023.06openalex-snapshot
Fungal mycobiome-mediated immune response: a non-negligible promoter in pancreatic oncogenesis and chemoresistance
inferred← citeshttps://doi.org/10.21037/tcr-23-2332openalex-snapshot
Machine learning-based integration of CD8 T cell-related gene signatures for comprehensive prognostic assessment in lung adenocarcinoma
inferred← citeshttps://doi.org/10.3389/fimmu.2024.1509658openalex-snapshot
Innovative strategies to optimise colorectal cancer immunotherapy through molecular mechanism insights
inferred← citeshttps://doi.org/10.3389/fimmu.2026.1685015openalex-snapshot
The emerging role of m6A methylation in prostate-related diseases: mechanisms and clinical implications
inferred← citeshttps://doi.org/10.3389/fimmu.2026.1713267openalex-snapshot
Integrative single-cell, spatial, and bulk transcriptomics reveal an FMR1–FTO axis linked to the immune-excluded phenotype in gastric cancer
inferred← citeshttps://doi.org/10.3389/fimmu.2026.1797535openalex-snapshot
RNA-binding motif proteins as context-dependent regulators of tumor–immune crosstalk, genome stability, and therapeutic vulnerabilities in cancer
inferred← citeshttps://doi.org/10.3389/fonc.2025.1534948openalex-snapshot
Biological functions of 5-methylcytosine RNA-binding proteins and their potential mechanisms in human cancers
inferred← citeshttps://doi.org/10.3390/biom15060779openalex-snapshot
FMR1: A Neurodevelopmental Factor Regulating Cell Metabolism in the Tumor Microenvironment
inferred← citeshttps://doi.org/10.3390/cancers16020269openalex-snapshot
MICA+ Tumor Cell Upregulated Macrophage-Secreted MMP9 via PROS1-AXL Axis to Induce Tumor Immune Escape in Advanced Hepatocellular Carcinoma (HCC)
inferred← citeshttps://doi.org/10.3390/ijms25137290openalex-snapshot
The Prognostic and Therapeutic Potential of Fragile X Mental Retardation 1 (FMR1) Gene Expression in Prostate Adenocarcinoma: Insights into Survival Outcomes and Oncogenic Pathway Modulation
inferred← citeshttps://doi.org/10.3390/ijms27010205openalex-snapshot
RNA-Binding Proteins: Modulators of Canonical Wnt Signaling Pathway
inferred← citeshttps://doi.org/10.4110/in.2025.25.e36openalex-snapshot
Unlocking IL-33: New Insights into Tumor Immunity
inferred← citeshttps://doi.org/10.6023/a23070316openalex-snapshot
RNA-Binding Proteome Analysis and Functional Explorations★
inferred← citeshttps://doi.org/10.62347/xvfp6530openalex-snapshot
The prognostic significance of FMR1 expression and its immunomodulatory implications in esophageal carcinoma
inferred← citeshttps://doi.org/10.70675/b2b42aebz2dd5z4743z8c66z2702c45a7634openalex-snapshot
Bioproduction de vésicules extracellulaires à partir de cultures de sphéroïdes de cellules humaines en bioréacteurs à cuves agitées
inferred← citeshttps://doi.org/10.7150/thno.99633openalex-snapshot
Oncofetal TRIM71 drives liver cancer carcinogenesis through remodeling CEBPA-mediated serine/glycine metabolism
inferred← citeshttps://doi.org/10.7717/peerj.15070openalex-snapshot
PAIP1 regulates expression of immune and inflammatory response associated genes at transcript level in liver cancer cell
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