On the public citation graph

Filociclovir Is a PotentIn VitroandIn VivoInhibitor of Human Adenoviruses

0 signed · 77 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.

Claim with ORCID

Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.

See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/jgm.1638openalex-snapshot

Targeted expression of herpes simplex virus thymidine kinase in adenovirus‐infected cells reduces virus titers upon treatment with ganciclovir in vitro

inferredcites →https://doi.org/10.1002/phar.2094openalex-snapshot

Brincidofovir as Salvage Therapy for Adenovirus Disease in Intestinal Transplant Recipients

inferredcites →https://doi.org/10.1016/j.antiviral.2014.10.005openalex-snapshot

Cidofovir and brincidofovir reduce the pathology caused by systemic infection with human type 5 adenovirus in immunosuppressed Syrian hamsters, while ribavirin is largely ineffective in this model

inferredcites →https://doi.org/10.1016/j.antiviral.2018.03.001openalex-snapshot

USC-087 protects Syrian hamsters against lethal challenge with human species C adenoviruses

inferredcites →https://doi.org/10.1016/j.antiviral.2018.09.015openalex-snapshot

A standardized approach to the evaluation of antivirals against DNA viruses: Orthopox-, adeno-, and herpesviruses

inferredcites →https://doi.org/10.1016/j.antiviral.2018.09.016openalex-snapshot

A standardized approach to the evaluation of antivirals against DNA viruses: Polyomaviruses and lymphotropic herpesviruses

inferredcites →https://doi.org/10.1016/j.antiviral.2020.104710openalex-snapshot

The discovery and development of filociclovir for the prevention and treatment of human cytomegalovirus-related disease

inferredcites →https://doi.org/10.1016/j.bbmt.2014.10.012openalex-snapshot

The Effect of Cidofovir on Adenovirus Plasma DNA Levels in Stem Cell Transplantation Recipients without T Cell Reconstitution

inferredcites →https://doi.org/10.1016/j.bbmt.2016.12.621openalex-snapshot

Brincidofovir for Asymptomatic Adenovirus Viremia in Pediatric and Adult Allogeneic Hematopoietic Cell Transplant Recipients: A Randomized Placebo-Controlled Phase II Trial

inferredcites →https://doi.org/10.1016/j.bcp.2010.09.005openalex-snapshot

Phosphorylation of antiviral and endogenous nucleotides to di- and triphosphates by guanosine monophosphate kinase

inferredcites →https://doi.org/10.1016/j.ijid.2017.07.011openalex-snapshot

Respiratory viruses in transplant recipients: more than just a cold. Clinical syndromes and infection prevention principles

inferredcites →https://doi.org/10.1016/j.jcv.2010.10.016openalex-snapshot

Eradication of disseminated adenovirus infection in a pediatric hematopoietic stem cell transplantation recipient using the novel antiviral agent CMX001

inferredcites →https://doi.org/10.1016/j.jcv.2017.09.013openalex-snapshot

Disseminated adenovirus infection after allogeneic stem cell transplant and the potential role of brincidofovir – Case series and 10 year experience of management in an adult transplant cohort

inferredcites →https://doi.org/10.1016/j.rmed.2013.09.008openalex-snapshot

Severe adenovirus pneumonia requiring extracorporeal membrane oxygenation support – Serotype 7 revisited

inferredcites →https://doi.org/10.1016/j.virol.2017.10.015openalex-snapshot

Male Syrian hamsters are more susceptible to intravenous infection with species C human adenoviruses than are females

inferredcites →https://doi.org/10.1021/jm030316sopenalex-snapshot

Synthesis and Antiviral Activity of (Z)- and (E)-2,2-[Bis(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines: Second-Generation Methylenecyclopropane Analogues of Nucleosides

inferredcites →https://doi.org/10.1038/srep01812openalex-snapshot

Molecular evolution of human adenoviruses

inferredcites →https://doi.org/10.1055/s-0036-1584923openalex-snapshot

Adenovirus: Epidemiology, Global Spread of Novel Serotypes, and Advances in Treatment and Prevention

inferredcites →https://doi.org/10.1056/nejmcpc1712222openalex-snapshot

Case 1-2018: A 39-Year-Old Woman with Rapidly Progressive Respiratory Failure

inferredcites →https://doi.org/10.1056/nejmoa1405870openalex-snapshot

Community-Acquired Pneumonia Requiring Hospitalization among U.S. Children

inferredcites →https://doi.org/10.1056/nejmoa1500245openalex-snapshot

Community-Acquired Pneumonia Requiring Hospitalization among U.S. Adults

inferredcites →https://doi.org/10.1073/pnas.0800200105openalex-snapshot

Hexadecyloxypropyl-cidofovir, CMX001, prevents adenovirus-induced mortality in a permissive, immunosuppressed animal model

inferredcites →https://doi.org/10.1080/15257770903172720openalex-snapshot

Synthesis and Enantioselectivity of Cyclopropavir Phosphates for Cellular GMP Kinase

inferredcites →https://doi.org/10.1086/380450openalex-snapshot

Real‐Time Blood Plasma Polymerase Chain Reaction for Management of Disseminated Adenovirus Infection

inferredcites →https://doi.org/10.1086/420817openalex-snapshot

Effect of Ribavirin on the Plasma Viral DNA Load in Patients with Disseminating Adenovirus Infection

inferredcites →https://doi.org/10.1086/426831openalex-snapshot

Ether Lipid‐Ester Prodrugs of Acyclic Nucleoside Phosphonates: Activity against Adenovirus Replication In Vitro

inferredcites →https://doi.org/10.1086/514978openalex-snapshot

Disseminated Adenovirus Disease in Immunocompromised and Immunocompetent Children

inferredcites →https://doi.org/10.1093/femsre/fuz008openalex-snapshot

Drug development against human adenoviruses and its advancement by Syrian hamster models

inferredcites →https://doi.org/10.1093/infdis/165.1.170openalex-snapshot

Adenovirus Infection in Pediatric Liver Transplant Recipients

inferredcites →https://doi.org/10.1093/infdis/jiz493openalex-snapshot

Advances in the Development of Therapeutics for Cytomegalovirus Infections

inferredcites →https://doi.org/10.1093/jpids/pix011openalex-snapshot

Renal Toxicity in Pediatric Patients Receiving Cidofovir for the Treatment of Adenovirus Infection

inferredcites →https://doi.org/10.1097/01.tp.0000209195.95115.8eopenalex-snapshot

Cidofovir for the Treatment of Adenoviral Infection in Pediatric Hematopoietic Stem Cell Transplant Patients

inferredcites →https://doi.org/10.1097/mph.0000000000001227openalex-snapshot

Brincidofovir (CMX001) Toxicity Associated With Epithelial Apoptosis and Crypt Drop Out in a Hematopoietic Cell Transplant Patient: Challenges in Distinguishing Drug Toxicity From GVHD

inferredcites →https://doi.org/10.1097/qco.0000000000000451openalex-snapshot

Human adenovirus infections: update and consideration of mechanisms of viral persistence

inferredcites →https://doi.org/10.1111/j.1600-6143.2009.02907.xopenalex-snapshot

Adenovirus in Solid Organ Transplant Recipients

inferredcites →https://doi.org/10.1128/aac.00429-13openalex-snapshot

Synthesis and Antiviral Activities of Methylenecyclopropane Analogs with 6-Alkoxy and 6-Alkylthio Substitutions That Exhibit Broad-Spectrum Antiviral Activity against Human Herpesviruses

inferredcites →https://doi.org/10.1128/aac.00449-16openalex-snapshot

Potency and Stereoselectivity of Cyclopropavir Triphosphate Action on Human Cytomegalovirus DNA Polymerase

inferredcites →https://doi.org/10.1128/aac.00468-10openalex-snapshot

Stereoselective Phosphorylation of Cyclopropavir by pUL97 and Competitive Inhibition by Maribavir

inferredcites →https://doi.org/10.1128/aac.00717-19openalex-snapshot

Phase Ib Trial To Evaluate the Safety and Pharmacokinetics of Multiple Ascending Doses of Filociclovir (MBX-400, Cyclopropavir) in Healthy Volunteers

inferredcites →https://doi.org/10.1128/aac.00978-13openalex-snapshot

Human Herpesvirus 6 U69 Kinase Phosphorylates the Methylenecyclopropane Nucleosides Cyclopropavir, MBX 2168, and MBX 1616 to Their Monophosphates

inferredcites →https://doi.org/10.1128/aac.01925-18openalex-snapshot

Cidofovir Diphosphate Inhibits Adenovirus 5 DNA Polymerase via both Nonobligate Chain Termination and Direct Inhibition, and Polymerase Mutations Confer Cidofovir Resistance on Intact Virus

inferredcites →https://doi.org/10.1128/aac.03860-14openalex-snapshot

Ganciclovir Inhibits Human Adenovirus Replication and Pathogenicity in Permissive Immunosuppressed Syrian Hamsters

inferredcites →https://doi.org/10.1128/aac.48.12.4745-4753.2004openalex-snapshot

Oral Activity of a Methylenecyclopropane Analog, Cyclopropavir, in Animal Models for Cytomegalovirus Infections

inferredcites →https://doi.org/10.1128/aac.49.3.1010-1016.2005openalex-snapshot

Antiadenovirus Activities of Several Classes of Nucleoside and Nucleotide Analogues

inferredcites →https://doi.org/10.1128/aac.49.3.1039-1045.2005openalex-snapshot

In Vitro Activity and Mechanism of Action of Methylenecyclopropane Analogs of Nucleosides against Herpesvirus Replication

inferredcites →https://doi.org/10.1128/cmr.00116-13openalex-snapshot

Adenovirus Infections in Immunocompetent and Immunocompromised Patients

inferredcites →https://doi.org/10.1128/jvi.00284-17openalex-snapshot

Pathology in Permissive Syrian Hamsters after Infection with Species C Human Adenovirus (HAdV-C) Is the Result of Virus Replication: HAdV-C6 Replicates More and Causes More Pathology than HAdV-C5

inferredcites →https://doi.org/10.1177/135965350501000204openalex-snapshot

In Vitro Susceptibility of Adenovirus to Antiviral Drugs is Species-Dependent

inferredcites →https://doi.org/10.1182/blood-2016-11-749721openalex-snapshot

Brincidofovir is highly efficacious in controlling adenoviremia in pediatric recipients of hematopoietic cell transplant

inferredcites →https://doi.org/10.15585/mmwr.mm6712a6openalex-snapshot

Notes from the Field: Fatalities Associated with Human Adenovirus Type 7 at a Substance Abuse Rehabilitation Facility — New Jersey, 2017

inferredcites →https://doi.org/10.2147/idr.s162669openalex-snapshot

Pathogenesis and management of adenoviral keratoconjunctivitis

inferredcites →https://doi.org/10.3109/23744235.2015.1055585openalex-snapshot

Fatal pneumonia cases caused by human adenovirus 55 in immunocompetent adults

inferredcites →https://doi.org/10.3201/eid0506.990609openalex-snapshot

Large, Persistent Epidemic of Adenovirus Type 4-Associated Acute Respiratory Disease in U.S. Army Trainees

inferredcites →https://doi.org/10.3201/eid1605.091633openalex-snapshot

Spread of Adenovirus to Geographically Dispersed Military Installations, May–October 2007

inferredcites →https://doi.org/10.3390/biomedicines6010030openalex-snapshot

The Repertoire of Adenovirus in Human Disease: The Innocuous to the Deadly

inferredcites →https://doi.org/10.3390/ph3103343openalex-snapshot

Anti-Viral Drugs for Human Adenoviruses

inferredcites →https://doi.org/10.3390/v7031409openalex-snapshot

Valganciclovir Inhibits Human Adenovirus Replication and Pathology in Permissive Immunosuppressed Female and Male Syrian Hamsters

inferredcites →https://doi.org/10.3390/v9060147openalex-snapshot

HAdV-C6 Is a More Relevant Challenge Virus than HAdV-C5 for Testing Antiviral Drugs with the Immunosuppressed Syrian Hamster Model

inferredcites →https://doi.org/10.7759/cureus.5296openalex-snapshot

Brincidofovir (CMX001) for the Treatment of Severe Adenoviral Pneumonia in Kidney Transplant Recipient

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4656748openalex-extracted

inferred← citeshttps://doi.org/10.1016/j.antiviral.2021.105034openalex-snapshot

Emerging antiviral therapeutics for human adenovirus infection: Recent developments and novel strategies

inferred← citeshttps://doi.org/10.1016/j.antiviral.2022.105431openalex-snapshot

Filociclovir is a potent inhibitor of human adenovirus F41

inferred← citeshttps://doi.org/10.1016/j.antiviral.2024.105799openalex-snapshot

Oral USC-093, a novel homoserinamide analogue of the tyrosinamide (S)-HPMPA prodrug USC-087 has decreased nephrotoxicity while maintaining antiviral efficacy against human adenovirus infection of Syrian hamsters

inferred← citeshttps://doi.org/10.1016/j.antiviral.2025.106155openalex-snapshot

Salicylamide derivative JMX0312 protects immunosuppressed Syrian hamsters against adenovirus lethal challenge

inferred← citeshttps://doi.org/10.1016/j.stem.2023.12.008openalex-snapshot

Human conjunctiva organoids to study ocular surface homeostasis and disease

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5c00868openalex-snapshot

Small-Molecule Strategies against Human Adenoviruses: Progress, Challenges, and Future Perspectives

inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.2c00668openalex-snapshot

NPP-669, a Novel Broad-Spectrum Antiviral Therapeutic with Excellent Cellular Uptake, Antiviral Potency, Oral Bioavailability, Preclinical Efficacy, and a Promising Safety Margin

inferred← citeshttps://doi.org/10.1080/17460794.2025.2577001openalex-snapshot

Identifying new strategies to combat cytomegalovirus by integrating existing and innovative approaches in diagnosis and treatment

inferred← citeshttps://doi.org/10.1128/aac.00489-24openalex-snapshot

NPP-669, a prodrug of cidofovir, is highly efficacious against human adenovirus infection in the permissive Syrian hamster model

inferred← citeshttps://doi.org/10.1128/jcm.00836-22openalex-snapshot

Adenovirus infections: new insights for the clinical laboratory

inferred← citeshttps://doi.org/10.1128/jvi.01184-21openalex-snapshot

Biographical Feature: William S. M. Wold, Ph.D., 1944–2021

inferred← citeshttps://doi.org/10.3389/fmicb.2023.1321116openalex-snapshot

Anti-CMV therapy, what next? A systematic review

inferred← citeshttps://doi.org/10.3389/fped.2024.1456250openalex-snapshot

Current antiviral agents against human adenoviruses associated with respiratory infections

inferred← citeshttps://doi.org/10.3390/microorganisms10102014openalex-snapshot

Antiviral Drugs in Adenovirus-Induced Keratoconjunctivitis

inferred← citeshttps://doi.org/10.3390/microorganisms9081599openalex-snapshot

Current and Future Antiviral Strategies to Tackle Gastrointestinal Viral Infections

inferred← citeshttps://doi.org/10.3390/ph14040294openalex-snapshot

Filociclovir Is an Active Antiviral Agent against Ocular Adenovirus Isolates In Vitro and in the Ad5/NZW Rabbit Ocular Model

inferred← citeshttps://doi.org/10.3390/v16081200openalex-snapshot

Longitudinal Monitoring of the Effects of Anti-Adenoviral Treatment Regimens in a Permissive In Vivo Model

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.