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Cidofovir Diphosphate Inhibits Adenovirus 5 DNA Polymerase via both Nonobligate Chain Termination and Direct Inhibition, and Polymerase Mutations Confer Cidofovir Resistance on Intact Virus

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/jmv.25041openalex-snapshot
Recombinant type Human mastadenovirus D85 associated with epidemic keratoconjunctivitis since 2015 in Japan
inferredcites →https://doi.org/10.1007/s11908-014-0416-yopenalex-snapshot
Adenovirus: Current Epidemiology and Emerging Approaches to Prevention and Treatment
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GSK983: A novel compound with broad-spectrum antiviral activity
inferredcites →https://doi.org/10.1016/j.antiviral.2009.01.005openalex-snapshot
Alkoxyalkyl prodrugs of acyclic nucleoside phosphonates enhance oral antiviral activity and reduce toxicity: Current state of the art
inferredcites →https://doi.org/10.1016/j.bbmt.2011.09.007openalex-snapshot
Safety and Efficacy of CMX001 as Salvage Therapy for Severe Adenovirus Infections in Immunocompromised Patients
inferredcites →https://doi.org/10.1016/s0166-3542(02)00098-0openalex-snapshot
Sequence changes in the human adenovirus type 5 DNA polymerase associated with resistance to the broad spectrum antiviral cidofovir
inferredcites →https://doi.org/10.1056/nejmcpc1712222openalex-snapshot
Case 1-2018: A 39-Year-Old Woman with Rapidly Progressive Respiratory Failure
inferredcites →https://doi.org/10.1086/505498openalex-snapshot
Emerging Infections: Adenovirus Infections in Transplant Recipients
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(S)-1-[3-Hydroxy-2-(Phosphonylmethoxy)propyl]cytosine (Cidofovir): Results of a Phase I/II Study of a Novel Antiviral Nucleotide Analogue
inferredcites →https://doi.org/10.1093/nar/25.9.1745openalex-snapshot
Processive proofreading by the adenovirus DNA polymerase. Association with the priming protein reduces exonucleolytic degradation
inferredcites →https://doi.org/10.1093/nar/26.5.1240openalex-snapshot
Adenovirus DNA polymerase: domain organisation and interaction with preterminal protein
inferredcites →https://doi.org/10.1097/00042560-199700001-00006openalex-snapshot
Clinical Experience With Cidofovir in the Treatment of Cytomegalovirus Retinitis
inferredcites →https://doi.org/10.1097/ftd.0000000000000353openalex-snapshot
Brincidofovir Is Not a Substrate for the Human Organic Anion Transporter 1: A Mechanistic Explanation for the Lack of Nephrotoxicity Observed in Clinical Studies
inferredcites →https://doi.org/10.1101/cshperspect.a013003openalex-snapshot
Adenovirus DNA Replication
inferredcites →https://doi.org/10.1128/aac.41.3.594openalex-snapshot
Effect of incorporation of cidofovir into DNA by human cytomegalovirus DNA polymerase on DNA elongation
inferredcites →https://doi.org/10.1128/aac.49.8.3153-3162.2005openalex-snapshot
Mechanism of Inhibition of Vaccinia Virus DNA Polymerase by Cidofovir Diphosphate
inferredcites →https://doi.org/10.1128/aac.49.9.3724-3733.2005openalex-snapshot
Comparative Activities of Lipid Esters of Cidofovir and Cyclic Cidofovir against Replication of Herpesviruses In Vitro
inferredcites →https://doi.org/10.1128/cmr.00116-13openalex-snapshot
Adenovirus Infections in Immunocompetent and Immunocompromised Patients
inferredcites →https://doi.org/10.1128/jvi.00739-12openalex-snapshot
Selective Modification of Adenovirus Replication Can Be Achieved through Rational Mutagenesis of the Adenovirus Type 5 DNA Polymerase
inferredcites →https://doi.org/10.1128/jvi.74.14.6401-6407.2000openalex-snapshot
Characterization of a Baculovirus Alkaline Nuclease
inferredcites →https://doi.org/10.1146/annurev-biochem-061516-044709openalex-snapshot
Eukaryotic DNA Replication Fork
inferredcites →https://doi.org/10.1182/blood-2010-04-259291openalex-snapshot
How I treat adenovirus in hematopoietic stem cell transplant recipients
inferredcites →https://doi.org/10.1182/blood-2016-11-749721openalex-snapshot
Brincidofovir is highly efficacious in controlling adenoviremia in pediatric recipients of hematopoietic cell transplant
inferredcites →https://doi.org/10.7326/0003-4819-126-4-199702150-00001openalex-snapshot
Intravenous Cidofovir for Peripheral Cytomegalovirus Retinitis in Patients with AIDS

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1016/j.virs.2026.03.017openalex-snapshot
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inferred← citeshttps://doi.org/10.1128/aac.00489-24openalex-snapshot
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inferred← citeshttps://doi.org/10.1128/aac.01299-20openalex-snapshot
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