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Extreme Acid Modulates Fitness Trade-Offs of Multidrug Efflux Pumps MdtEF-TolC and AcrAB-TolC in Escherichia coli K-12

https://doi.org/10.1128/aem.00724-21
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Author Correction: Antibiotic drug-resistance as a complex system driven by socio-economic growth and antibiotic misuse
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Bile salts and fatty acids induce the expression of Escherichia coli AcrAB multidrug efflux pump through their interaction with Rob regulatory protein
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GadE (YhiE) activates glutamate decarboxylase‐dependent acid resistance in Escherichia coli K‐12
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One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
inferredcites →https://doi.org/10.1073/pnas.1218348109openalex-snapshot
Multidrug binding properties of the AcrB efflux pump characterized by molecular dynamics simulations
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Select and resequence reveals relative fitness of bacteria in symbiotic and free-living environments
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Emr, an Escherichia coli locus for multidrug resistance.
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The Multidrug Efflux Pump MdtEF Protects against Nitrosative Damage during the Anaerobic Respiration in Escherichia coli
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Identification of Oligomerization and Drug-binding Domains of the Membrane Fusion Protein EmrA
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AcrA, AcrB, and TolC of Escherichia coli Form a Stable Intermembrane Multidrug Efflux Complex
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Long-Term Experimental Evolution in Escherichia coli. I. Adaptation and Divergence During 2,000 Generations
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Aspirin, sodium benzoate and sodium salicylate reverse resistance to colistin in Enterobacteriaceae andPseudomonas aeruginosa
inferredcites →https://doi.org/10.1093/nar/gkq097openalex-snapshot
Acid stress response in Escherichia coli: mechanism of regulation of gadA transcription by RcsB and GadE
inferredcites →https://doi.org/10.1099/mic.0.000271openalex-snapshot
Roles of Lon protease and its substrate MarA during sodium salicylate-mediated growth reduction and antibiotic resistance in Escherichia coli
inferredcites →https://doi.org/10.1099/mic.0.26659-0openalex-snapshot
GadE (YhiE): a novel activator involved in the response to acid environment in Escherichia coli
inferredcites →https://doi.org/10.1101/570408openalex-snapshot
The Anaerobic Efflux Pump MdtEF-TolC Confers Resistance to Cationic Biocides
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Interactions between bile salts, gut microbiota, and hepatic innate immunity
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A 750 bp sensory integration region directs global control of the Escherichia coli GadE acid resistance regulator
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Characterization of mutations in the PAS domain of the EvgS sensor kinase selected by laboratory evolution for acid resistance in E scherichia coli
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Role of AcrAB-TolC multidrug efflux pump in drug-resistance acquisition by plasmid transfer
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Antibiotic Susceptibility Profiles of Escherichia coli Strains Lacking Multidrug Efflux Pump Genes
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Acid Evolution of Escherichia coli K-12 Eliminates Amino Acid Decarboxylases and Reregulates Catabolism
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Inverted Regulation of Multidrug Efflux Pumps, Acid Resistance, and Porins in Benzoate-Evolved Escherichia coli K-12
inferredcites →https://doi.org/10.1128/aem.02736-16openalex-snapshot
Benzoate- and Salicylate-Tolerant Strains of Escherichia coli K-12 Lose Antibiotic Resistance during Laboratory Evolution
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inferredcites →https://doi.org/10.1128/cmr.00117-14openalex-snapshot
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inferredcites →https://doi.org/10.1128/jb.00371-10openalex-snapshot
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inferredcites →https://doi.org/10.1128/jb.00507-09openalex-snapshot
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Products of theEscherichia coliAcid Fitness Island Attenuate Metabolite Stress at Extremely Low pH and Mediate a Cell Density-Dependent Acid Resistance
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Escherichia coli HdeB Is an Acid Stress Chaperone
inferredcites →https://doi.org/10.1128/jb.01729-07openalex-snapshot
Role of the Multidrug Resistance Regulator MarA in Global Regulation of the hdeAB Acid Resistance Operon in Escherichia coli
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Regulation of ompF porin expression by salicylate in Escherichia coli
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Active efflux of bile salts by Escherichia coli
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Escherichia coli Glutamate- and Arginine-Dependent Acid Resistance Systems Increase Internal pH and Reverse Transmembrane Potential
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Characterization of EvgAS-YdeO-GadE Branched Regulatory Circuit Governing Glutamate-Dependent Acid Resistance inEscherichia coli
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Mechanism of Growth Inhibition by Free Bile Acids in Lactobacilli and Bifidobacteria
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Proton-dependent multidrug efflux systems
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Guts and Gall: Bile Acids in Regulation of Intestinal Epithelial Function in Health and Disease
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pH Modulation of Efflux Pump Activity of Multi-Drug Resistant Escherichia coli: Protection During Its Passage and Eventual Colonization of the Colon
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A Requirement of TolC and MDR Efflux Pumps for Acid Adaptation and GadAB Induction in Escherichia coli
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The Evolution of Stomach Acidity and Its Relevance to the Human Microbiome
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Anaerobic expression of the gadE-mdtEF multidrug efflux operon is primarily regulated by the two-component system ArcBA through antagonizing the H-NS mediated repression
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The ins and outs of RND efflux pumps in Escherichia coli
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A Numbering System for MFS Transporter Proteins
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Resistance Training with Co-ingestion of Anti-inflammatory Drugs Attenuates Mitochondrial Function
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New Roads Leading to Old Destinations: Efflux Pumps as Targets to Reverse Multidrug Resistance in Bacteria
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Roles of Multidrug Efflux Pumps on the Biofilm Formation of Escherichia coli K-12

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Non-antibiotic pharmaceuticals are toxic against Escherichia coli with no evolution of cross-resistance to antibiotics
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Molecular insights into the determinants of substrate specificity and efflux inhibition of the RND efflux pumps AcrB and AdeB
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