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The ORF7b Protein of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Is Expressed in Virus-Infected Cells and Incorporated into SARS-CoV Particles

https://doi.org/10.1128/jvi.01691-06
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Severe Acute Respiratory Syndrome Coronavirus Infection of Golden Syrian Hamsters
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Severe Acute Respiratory Syndrome Coronavirus Group-Specific Open Reading Frames Encode Nonessential Functions for Replication in Cell Cultures and Mice
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Civets Are Equally Susceptible to Experimental Infection by Two Different Severe Acute Respiratory Syndrome Coronavirus Isolates
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Severe Acute Respiratory Syndrome Coronavirus 3a Protein Is a Viral Structural Protein
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Severe Acute Respiratory Syndrome Coronavirus 3a Protein Is Released in Membranous Structures from 3a Protein-Expressing Cells and Infected Cells
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Neither the RNA nor the Proteins of Open Reading Frames 3a and 3b of the Coronavirus Infectious Bronchitis Virus Are Essential for Replication
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7a Protein of Severe Acute Respiratory Syndrome Coronavirus Inhibits Cellular Protein Synthesis and Activates p38 Mitogen-Activated Protein Kinase
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Antibodies against West Nile Virus Nonstructural Protein NS1 Prevent Lethal Infection through Fc γ Receptor-Dependent and -Independent Mechanisms
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Viral Discovery and Sequence Recovery Using DNA Microarrays
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SARS-CoV-2 gene content and COVID-19 mutation impact by comparing 44 Sarbecovirus genomes
inferred← citeshttps://doi.org/10.1038/s41467-021-25361-5openalex-snapshot
A high-resolution temporal atlas of the SARS-CoV-2 translatome and transcriptome
inferred← citeshttps://doi.org/10.1038/s41580-021-00432-zopenalex-snapshot
Structures and functions of coronavirus replication–transcription complexes and their relevance for SARS-CoV-2 drug design
inferred← citeshttps://doi.org/10.1038/s41586-020-2739-1openalex-snapshot
The coding capacity of SARS-CoV-2
inferred← citeshttps://doi.org/10.1038/s41598-022-16533-4openalex-snapshot
Mutational induction in SARS-CoV-2 major lineages by experimental exposure to neutralising sera
inferred← citeshttps://doi.org/10.1038/s42003-021-02866-9openalex-snapshot
Amantadine inhibits known and novel ion channels encoded by SARS-CoV-2 in vitro
inferred← citeshttps://doi.org/10.1063/5.0163052openalex-snapshot
Uncovering the geometry of protein interaction network: The case of SARS-CoV-2 protein interactome
inferred← citeshttps://doi.org/10.1073/pnas.2407731121openalex-snapshot
Analysis of the structure and interactions of the SARS-CoV-2 ORF7b accessory protein
inferred← citeshttps://doi.org/10.1080/0889311x.2023.2173744openalex-snapshot
Structural biology of SARS-CoV-2 accessory proteins
inferred← citeshttps://doi.org/10.1080/15476286.2021.1975388openalex-snapshot
Duplex formation between the template and the nascent strand in the transcription-regulating sequences is associated with the site of template switching in SARS – CoV-2
inferred← citeshttps://doi.org/10.1093/molbev/msaa231openalex-snapshot
Potential Pathogenicity Determinants Identified from Structural Proteomics of SARS-CoV and SARS-CoV-2
inferred← citeshttps://doi.org/10.1093/nar/gkaa1116openalex-snapshot
Translational control of coronaviruses
inferred← citeshttps://doi.org/10.1093/nar/gkac144openalex-snapshot
Nanopore ReCappable sequencing maps SARS-CoV-2 5′ capping sites and provides new insights into the structure of sgRNAs
inferred← citeshttps://doi.org/10.1093/nar/gkae687openalex-snapshot
Improved sub-genomic RNA prediction with the ARTIC protocol
inferred← citeshttps://doi.org/10.1093/ve/veaa057openalex-snapshot
Intra-genome variability in the dinucleotide composition of SARS-CoV-2
inferred← citeshttps://doi.org/10.1097/cm9.0000000000002158openalex-snapshot
Functional mutations of SARS-CoV-2: implications to viral transmission, pathogenicity and immune escape
inferred← citeshttps://doi.org/10.1099/jgv.0.001453openalex-snapshot
SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology
inferred← citeshttps://doi.org/10.1099/jgv.0.001469openalex-snapshot
A putative new SARS-CoV protein, 3c, encoded in an ORF overlapping ORF3a
inferred← citeshttps://doi.org/10.1101/2020.03.05.976167openalex-snapshot
Direct RNA sequencing and early evolution of SARS-CoV-2
inferred← citeshttps://doi.org/10.1101/2020.04.16.043224openalex-snapshot
Meta-transcriptomic analysis reveals the gene expression and novel conserved sub-genomic RNAs in SARS-CoV-2 and MERS-CoV
inferred← citeshttps://doi.org/10.1101/2020.05.23.104919openalex-snapshot
In silico Proteome analysis of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
inferred← citeshttps://doi.org/10.1101/2020.07.16.207308openalex-snapshot
SARS-CoV-2 structural coverage map reveals state changes that disrupt host immunity
inferred← citeshttps://doi.org/10.1101/2020.07.31.230607openalex-snapshot
Biochemical and mathematical lessons from the evolution of the SARS-CoV-2 virus: paths for novel antiviral warfare
inferred← citeshttps://doi.org/10.1101/2020.08.28.272955openalex-snapshot
Global BioID-based SARS-CoV-2 proteins proximal interactome unveils novel ties between viral polypeptides and host factors involved in multiple COVID19-associated mechanisms
inferred← citeshttps://doi.org/10.1101/2020.11.13.381228openalex-snapshot
Analysis of the Dynamics and Distribution of SARS-CoV-2 Mutations and its Possible Structural and Functional Implications
inferred← citeshttps://doi.org/10.1101/2021.02.05.428650openalex-snapshot
SARS-CoV-2 ORF7b: is a bat virus protein homologue a major cause of COVID-19 symptoms?
inferred← citeshttps://doi.org/10.1101/2021.10.01.452232openalex-snapshot
Characterization and Structural Prediction of ORF10, ORF7b, ORF7a, ORF6, Membrane Glycoprotein, and Envelope Protein in SARS-CoV-2 Bangladeshi Variant through Bioinformatics Approach
inferred← citeshttps://doi.org/10.1101/2022.06.01.494101openalex-snapshot
Antiviral immune responses, cellular metabolism and adhesion are differentially modulated by SARS-CoV-2 ORF7a or ORF7b
inferred← citeshttps://doi.org/10.1101/2022.09.27.509702openalex-snapshot
Cell type-independent profiling of interactions between intracellular pathogens and the human phosphoproteome
inferred← citeshttps://doi.org/10.1101/2022.10.25.513760openalex-snapshot
One for all – Human kidney Caki-1 cells are highly susceptible to infection with corona- and other respiratory viruses
inferred← citeshttps://doi.org/10.1101/2023.03.03.531067openalex-snapshot
Convergent Evolution of A-Lineage (Clade 19B) SARS-CoV-2 Spike Sequences with B-Lineage Variants of Concern Affects Virus Replication in a Temperature-Dependent Manner on Human Nasal Epithelial Cell Cultures
inferred← citeshttps://doi.org/10.1111/ajt.16933openalex-snapshot
A third dose of SARS-CoV-2 vaccine increases neutralizing antibodies against variants of concern in solid organ transplant recipients
inferred← citeshttps://doi.org/10.1111/cei.13523openalex-snapshot
Innate immunity during SARS-CoV-2: evasion strategies and activation trigger hypoxia and vascular damage
inferred← citeshttps://doi.org/10.1126/sciadv.ade5085openalex-snapshot
The D614G mutation redirects SARS-CoV-2 spike to lysosomes and suppresses deleterious traits of the furin cleavage site insertion mutation
inferred← citeshttps://doi.org/10.1126/scitranslmed.adn7527openalex-snapshot
SARS-CoV-2 induces neutrophil degranulation and differentiation into myeloid-derived suppressor cells associated with severe COVID-19
inferred← citeshttps://doi.org/10.1128/9781555815493.ch12openalex-snapshot
Developments in the Search for Small-Molecule Inhibitors for Treatment of Severe Acute Respiratory Syndrome Coronavirus
inferred← citeshttps://doi.org/10.1128/9781555815790.ch12openalex-snapshot
Coronavirus Structural Proteins and Virus Assembly
inferred← citeshttps://doi.org/10.1128/9781555815790.ch25openalex-snapshot
Vaccines for Severe Acute Respiratory Syndrome Virus and Other Coronaviruses
inferred← citeshttps://doi.org/10.1128/jvi.00402-21openalex-snapshot
Contribution of SARS-CoV-2 Accessory Proteins to Viral Pathogenicity in K18 Human ACE2 Transgenic Mice
inferred← citeshttps://doi.org/10.1128/jvi.00555-23openalex-snapshot
One for all—human kidney Caki-1 cells are highly susceptible to infection with corona- and other respiratory viruses
inferred← citeshttps://doi.org/10.1128/jvi.00680-24openalex-snapshot
Mouse hepatitis virus JHMV I protein is required for maximal virulence
inferred← citeshttps://doi.org/10.1128/jvi.00784-08openalex-snapshot
The Transmembrane Domain of the Severe Acute Respiratory Syndrome Coronavirus ORF7b Protein Is Necessary and Sufficient for Its Retention in the Golgi Complex
inferred← citeshttps://doi.org/10.1128/jvi.01012-07openalex-snapshot
Severe Acute Respiratory Syndrome Coronavirus ORF6 Antagonizes STAT1 Function by Sequestering Nuclear Import Factors on the Rough Endoplasmic Reticulum/Golgi Membrane
inferred← citeshttps://doi.org/10.1128/jvi.01266-07openalex-snapshot
Severe Acute Respiratory Syndrome Coronavirus Gene 7 Products Contribute to Virus-Induced Apoptosis
inferred← citeshttps://doi.org/10.1128/jvi.01631-07openalex-snapshot
The 29-Nucleotide Deletion Present in Human but Not in Animal Severe Acute Respiratory Syndrome Coronaviruses Disrupts the Functional Expression of Open Reading Frame 8
inferred← citeshttps://doi.org/10.1128/jvi.02307-06openalex-snapshot
Severe Acute Respiratory Syndrome Coronavirus Accessory Protein 6 Is a Virion-Associated Protein and Is Released from 6 Protein-Expressing Cells
inferred← citeshttps://doi.org/10.1128/jvi.02406-07openalex-snapshot
Severe Acute Respiratory Syndrome Coronavirus Protein 6 Accelerates Murine Hepatitis Virus Infections by More than One Mechanism
inferred← citeshttps://doi.org/10.1128/jvi.02458-09openalex-snapshot
A Single Tyrosine in the Severe Acute Respiratory Syndrome Coronavirus Membrane Protein Cytoplasmic Tail Is Important for Efficient Interaction with Spike Protein
inferred← citeshttps://doi.org/10.1128/jvi.02570-09openalex-snapshot
The N-Terminal Region of Severe Acute Respiratory Syndrome Coronavirus Protein 6 Induces Membrane Rearrangement and Enhances Virus Replication
inferred← citeshttps://doi.org/10.1128/jvi.02631-07openalex-snapshot
Proteomics Analysis Unravels the Functional Repertoire of Coronavirus Nonstructural Protein 3
inferred← citeshttps://doi.org/10.1128/jvi.06223-11openalex-snapshot
The Andes Hantavirus NSs Protein Is Expressed from the Viral Small mRNA by a Leaky Scanning Mechanism
inferred← citeshttps://doi.org/10.1128/mbio.00810-24openalex-snapshot
Bystander monocytic cells drive infection-independent NLRP3 inflammasome response to SARS-CoV-2
inferred← citeshttps://doi.org/10.1128/mbio.00974-21openalex-snapshot
Sex Differences in Lung Imaging and SARS-CoV-2 Antibody Responses in a COVID-19 Golden Syrian Hamster Model
inferred← citeshttps://doi.org/10.1128/mmbr.00015-08openalex-snapshot
Mechanisms of Severe Acute Respiratory Syndrome Pathogenesis and Innate Immunomodulation
inferred← citeshttps://doi.org/10.1128/spectrum.01025-22openalex-snapshot
Evaluation of Four Point of Care (POC) Antigen Assays for the Detection of the SARS-CoV-2 Variant Omicron
inferred← citeshttps://doi.org/10.1134/s0006297925601212openalex-snapshot
Progress in CRISPR/Cas13-Mediated Suppression of Influenza A and SARS-CoV-2 Virus Infection in in vitro and in vivo Models
inferred← citeshttps://doi.org/10.1146/annurev-biochem-052621-091439openalex-snapshot
The Coronavirus Replication–Transcription Complex
inferred← citeshttps://doi.org/10.1172/jci.insight.122678openalex-snapshot
IL-1 receptor antagonist therapy mitigates placental dysfunction and perinatal injury following Zika virus infection
inferred← citeshttps://doi.org/10.1172/jci.insight.155944openalex-snapshot
Adaptive immune responses in vaccinated patients with symptomatic SARS-CoV-2 Alpha infection
inferred← citeshttps://doi.org/10.1172/jci142004openalex-snapshot
Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population
inferred← citeshttps://doi.org/10.1172/jci146927openalex-snapshot
Antibody responses to endemic coronaviruses modulate COVID-19 convalescent plasma functionality
inferred← citeshttps://doi.org/10.1177/11779322211025876openalex-snapshot
Structure and Function of Major SARS-CoV-2 and SARS-CoV Proteins
inferred← citeshttps://doi.org/10.1177/11786361221115595openalex-snapshot
Characterization and Structural Prediction of Proteins in SARS-CoV-2 Bangladeshi Variant Through Bioinformatics
inferred← citeshttps://doi.org/10.1186/1743-422x-6-131openalex-snapshot
Reverse genetic characterization of the natural genomic deletion in SARS-Coronavirus strain Frankfurt-1 open reading frame 7b reveals an attenuating function of the 7b protein in-vitro and in-vivo
inferred← citeshttps://doi.org/10.1186/s12859-021-04045-3openalex-snapshot
In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of a possible putative protective effect
inferred← citeshttps://doi.org/10.1186/s12929-024-01062-1openalex-snapshot
A glimpse into viral warfare: decoding the intriguing role of highly pathogenic coronavirus proteins in apoptosis regulation
inferred← citeshttps://doi.org/10.1186/s12985-022-01920-0openalex-snapshot
SARS-CoV-2 accessory protein 7b forms homotetramers in detergent
inferred← citeshttps://doi.org/10.1186/s13059-020-02191-0openalex-snapshot
Potentially adaptive SARS-CoV-2 mutations discovered with novel spatiotemporal and explainable AI models
inferred← citeshttps://doi.org/10.1261/rna.078969.121openalex-snapshot
sgDI-tector: defective interfering viral genome bioinformatics for detection of coronavirus subgenomic RNAs
inferred← citeshttps://doi.org/10.1371/journal.pone.0003299openalex-snapshot
Genome-Wide Analysis of Protein-Protein Interactions and Involvement of Viral Proteins in SARS-CoV Replication
inferred← citeshttps://doi.org/10.1371/journal.ppat.1002315openalex-snapshot
Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Regulates Cell Stress Response and Apoptosis
inferred← citeshttps://doi.org/10.1371/journal.ppat.1009800openalex-snapshot
SARS-CoV-2 suppresses IFNβ production mediated by NSP1, 5, 6, 15, ORF6 and ORF7b but does not suppress the effects of added interferon
inferred← citeshttps://doi.org/10.14573/altex.2006111openalex-snapshot
Infectability of Human BrainSphere Neurons Suggests Neurotropism of SARS-CoV-2*
inferred← citeshttps://doi.org/10.15252/msb.202010079openalex-snapshot
SARS‐CoV‐2 structural coverage map reveals viral protein assembly, mimicry, and hijacking mechanisms
inferred← citeshttps://doi.org/10.1586/erv.09.43openalex-snapshot
SARS vaccines: where are we?
inferred← citeshttps://doi.org/10.1590/1678-4685-gmb-2020-0212openalex-snapshot
Molecular mechanisms and pharmacological interventions in the replication cycle of human coronaviruses
inferred← citeshttps://doi.org/10.20944/preprints202003.0320.v1openalex-snapshot
Molecular Analyses of Over Hundred Sixty Clinical Isolates of SARS-CoV-2: Insights on Likely Origin, Evolution and Spread, and Possible Intervention
inferred← citeshttps://doi.org/10.20944/preprints202004.0405.v1openalex-snapshot
Some Findings on Genes over SARS-CoV2 Genomes
inferred← citeshttps://doi.org/10.20944/preprints202004.0405.v2openalex-snapshot
Some Findings on Genes over SARS-CoV2 Genomes
inferred← citeshttps://doi.org/10.20944/preprints202103.0416.v1openalex-snapshot
Science’s Response to COVID-19
inferred← citeshttps://doi.org/10.21203/rs.3.rs-105598/v1openalex-snapshot
In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of possible putative protective effect
inferred← citeshttps://doi.org/10.21203/rs.3.rs-105598/v2openalex-snapshot
In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of possible putative protective effect
inferred← citeshttps://doi.org/10.21203/rs.3.rs-105598/v3openalex-snapshot
In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of a possible putative protective effect
inferred← citeshttps://doi.org/10.21203/rs.3.rs-1446025/v1openalex-snapshot
SARS-CoV 2 accessory protein 7b forms homotetramers in detergent
inferred← citeshttps://doi.org/10.2147/hiv.s300055openalex-snapshot
SARS-CoV-2 and Human Immunodeficiency Virus: Pathogen Pincer Attack
inferred← citeshttps://doi.org/10.2174/1566524021666210223143243openalex-snapshot
SARS-CoV-2 Proteins: Are They Useful as Targets for COVID-19 Drugs and Vaccines?
inferred← citeshttps://doi.org/10.2174/1872208316666220504234800openalex-snapshot
Proteome Exploration of Human Coronaviruses for Identifying Novel Vaccine Candidate: A Hierarchical Subtractive Genomics and Reverse Vaccinology Approach
inferred← citeshttps://doi.org/10.2217/fmb-2024-0010openalex-snapshot
JN.1: ongoing considerations of the shifting landscape of SARS-CoV-2 variants
inferred← citeshttps://doi.org/10.2217/fvl.11.33openalex-snapshot
Recent Developments in Anti-Severe Acute Respiratory Syndrome Coronavirus Chemotherapy
inferred← citeshttps://doi.org/10.22541/au.159407185.56107231openalex-snapshot
Structural, molecular biology and the immunopathology of SARS-CoV-2: An updated review
inferred← citeshttps://doi.org/10.26434/chemrxiv.12278588openalex-snapshot
Identification of Potential Binders of the SARS-Cov-2 Spike Protein via Molecular Docking, Dynamics Simulation and Binding Free Energy Calculation
inferred← citeshttps://doi.org/10.26508/lsa.202101347openalex-snapshot
Subgenomic RNA profiling suggests novel mechanism in coronavirus gene regulation and host adaption
inferred← citeshttps://doi.org/10.31219/osf.io/kzb9xopenalex-snapshot
BLAST Analysis of Sars-Cov-2 deliniates the functionality of the virus's protein
inferred← citeshttps://doi.org/10.32350/bsr.44.09openalex-snapshot
Molecular Basis of the Structure and Transmission of SARS-CoV, SARS-CoV-2, and MERS: A Review Report
inferred← citeshttps://doi.org/10.32657/10356/6568openalex-snapshot
Molecular characterization of coronavirus envelope and membrane proteins
inferred← citeshttps://doi.org/10.3389/fimmu.2021.708264openalex-snapshot
SARS-CoV-2 Accessory Proteins in Viral Pathogenesis: Knowns and Unknowns
inferred← citeshttps://doi.org/10.3389/fimmu.2022.857490openalex-snapshot
Translational Control of COVID-19 and Its Therapeutic Implication
inferred← citeshttps://doi.org/10.3390/cells10040821openalex-snapshot
Role of Structural and Non-Structural Proteins and Therapeutic Targets of SARS-CoV-2 for COVID-19
inferred← citeshttps://doi.org/10.3390/ijms27136022openalex-snapshot
Structural Features of a Tiny Viral Protein, ORF7b of SARS-CoV-2
inferred← citeshttps://doi.org/10.3390/pathogens11080877openalex-snapshot
Hydrophobic Alpha-Helical Short Peptides in Overlapping Reading Frames of the Coronavirus Genome
inferred← citeshttps://doi.org/10.3390/v15081763openalex-snapshot
MDM2 Influences ACE2 Stability and SARS-CoV-2 Uptake
inferred← citeshttps://doi.org/10.3390/v4112902openalex-snapshot
The Role of Severe Acute Respiratory Syndrome (SARS)-Coronavirus Accessory Proteins in Virus Pathogenesis
inferred← citeshttps://doi.org/10.37256/amtt.5120243631openalex-snapshot
Historical Perspectives of SARS-CoV-2 Viral Subversion of Host Cell: Biochemical and Pathological Aspects
inferred← citeshttps://doi.org/10.5802/crbiol.16openalex-snapshot
Leçons biochimiques et statistiques de l’évolution du virus SARS-CoV-2 : nouveaux chemins pour combattre les virus
inferred← citeshttps://doi.org/10.59049/2790-0231.1094openalex-snapshot
The molecular basis of the severe acute respiratory syndrome coronavirus 2 (sars-cov-2)
inferred← citeshttps://doi.org/10.6084/m9.figshare.13487342openalex-snapshot
Additional file 1 of Potentially adaptive SARS-CoV-2 mutations discovered with novel spatiotemporal and explainable AI models
inferred← citeshttps://doi.org/10.6084/m9.figshare.13487348openalex-snapshot
Additional file 3 of Potentially adaptive SARS-CoV-2 mutations discovered with novel spatiotemporal and explainable AI models
inferred← citeshttps://doi.org/10.6084/m9.figshare.14329681openalex-snapshot
Additional file 1 of In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of a possible putative protective effect
inferred← citeshttps://doi.org/10.6084/m9.figshare.14329684openalex-snapshot
Additional file 2 of In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of a possible putative protective effect
inferred← citeshttps://doi.org/10.6084/m9.figshare.14329687openalex-snapshot
Additional file 3 of In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of a possible putative protective effect
inferred← citeshttps://doi.org/10.6084/m9.figshare.14329690openalex-snapshot
Additional file 4 of In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of a possible putative protective effect
inferred← citeshttps://doi.org/10.6084/m9.figshare.21621762openalex-snapshot
Additional file 1 of SARS-CoV-2 accessory protein 7b forms homotetramers in detergent
inferred← citeshttps://doi.org/10.70675/68da4238zea7cz4ed3z8cc0z4df6aa8c5c3dopenalex-snapshot
Intracellular trafficking of the M protein of Middle East respiratory syndrome coronavirus (MERS-CoV)
inferred← citeshttps://doi.org/10.70675/85b003c5z09b3z47a1z9d43z4b2bc2c38c4aopenalex-snapshot
The accessory glycoprotein gp3 of canine Coronavirus type 1 : investigations of sequence variability in feline host and of the basic features of the different variants
inferred← citeshttps://doi.org/10.70675/bf6d9273z54c7z490ez9112z8b0a29244105openalex-snapshot
Contrôle traductionnel du SARS-CoV-2
inferred← citeshttps://doi.org/10.70675/d9508fc4zda51z4397za492zee1866100313openalex-snapshot
Rôle des cyclophilines dans la réplication des Coronavirus
inferred← citeshttps://doi.org/10.7717/peerj.9576openalex-snapshot
Understanding genomic diversity, pan-genome, and evolution of SARS-CoV-2
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