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Research Progress on NK Cell Receptors and Their Signaling Pathways

https://doi.org/10.1155/2020/6437057

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/0471142735.im1109bs90openalex-snapshot

Signal Transduction During Activation and Inhibition of Natural Killer Cells

inferredcites →https://doi.org/10.1002/1521-4141(200003)30:3<787::aid-immu787>3.0.co;2-iopenalex-snapshot

2B4 functions as a co-receptor in human NK cell activation

inferredcites →https://doi.org/10.1002/1529-0131(200006)43:6<1204::aid-anr3>3.0.co;2-iopenalex-snapshot

Natural killer cells and natural killer T cells

inferredcites →https://doi.org/10.1002/eji.1830250904openalex-snapshot

Molecular characterization of human CD94: A type II membrane glycoprotein related to the C‐type lectin superfamily

inferredcites →https://doi.org/10.1002/eji.1830270230openalex-snapshot

The CD94 and NKG2‐A C‐type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules

inferredcites →https://doi.org/10.1002/eji.200939502openalex-snapshot

ULBP6/RAET1L is an additional human NKG2D ligand

inferredcites →https://doi.org/10.1007/s00251-005-0078-xopenalex-snapshot

NKG2D splice variants: a reexamination of adaptor molecule associations

inferredcites →https://doi.org/10.1007/s10522-015-9581-0openalex-snapshot

Expression of NKp30, NKp46 and DNAM-1 activating receptors on resting and IL-2 activated NK cells from healthy donors according to CMV-serostatus and age

inferredcites →https://doi.org/10.1016/j.bcp.2010.05.002openalex-snapshot

PGE2 inhibits natural killer and γδ T cell cytotoxicity triggered by NKR and TCR through a cAMP-mediated PKA type I-dependent signaling

inferredcites →https://doi.org/10.1016/j.cellimm.2018.10.004openalex-snapshot

NK cells suppress CD8+ T cell immunity via NKG2D in severe aplastic anemia

inferredcites →https://doi.org/10.1016/j.clim.2018.10.014openalex-snapshot

2B4 and CD48: A powerful couple of the immune system

inferredcites →https://doi.org/10.1016/j.clim.2018.10.022openalex-snapshot

2B4 dysfunction in XLP1 NK cells: More than inability to control EBV infection

inferredcites →https://doi.org/10.1016/j.immuni.2004.06.020openalex-snapshot

Coordinated Induction by IL15 of a TCR-Independent NKG2D Signaling Pathway Converts CTL into Lymphokine-Activated Killer Cells in Celiac Disease

inferredcites →https://doi.org/10.1016/j.immuni.2008.07.014openalex-snapshot

Inhibitory Receptor Signaling via Tyrosine Phosphorylation of the Adaptor Crk

inferredcites →https://doi.org/10.1016/j.immuni.2009.06.017openalex-snapshot

Altered NK Cell Development and Enhanced NK Cell-Mediated Resistance to Mouse Cytomegalovirus in NKG2D-Deficient Mice

inferredcites →https://doi.org/10.1016/j.immuni.2010.02.004openalex-snapshot

Synergistic Signals for Natural Cytotoxicity Are Required to Overcome Inhibition by c-Cbl Ubiquitin Ligase

inferredcites →https://doi.org/10.1016/j.immuni.2012.03.023openalex-snapshot

The Adaptor SAP Controls NK Cell Activation by Regulating the Enzymes Vav-1 and SHIP-1 and by Enhancing Conjugates with Target Cells

inferredcites →https://doi.org/10.1016/j.jaut.2017.04.001openalex-snapshot

Contribution of inhibitory receptor TIGIT to NK cell education

inferredcites →https://doi.org/10.1016/j.str.2019.01.009openalex-snapshot

Conformational Changes in the Cytoplasmic Region of KIR3DL1 upon Interaction with SHP-2

inferredcites →https://doi.org/10.1016/s0021-9258(18)35930-1openalex-snapshot

Interaction between protein kinase C-dependent and G protein-dependent pathways in the regulation of natural killer cell granule exocytosis.

inferredcites →https://doi.org/10.1016/s0198-8859(99)00162-7openalex-snapshot

The human natural cytotoxicity receptors (NCR) that induce HLA class I-independent NK cell triggering

inferredcites →https://doi.org/10.1016/s1074-7613(00)80136-3openalex-snapshot

Physical and Functional Association of LFA-1 with DNAM-1 Adhesion Molecule

inferredcites →https://doi.org/10.1016/s1074-7613(00)80276-9openalex-snapshot

Sequential Involvement of Lck and SHP-1 with MHC-Recognizing Receptors on NK Cells Inhibits FcR-Initiated Tyrosine Kinase Activation

inferredcites →https://doi.org/10.1016/s1074-7613(00)80529-4openalex-snapshot

A Novel Immunoglobulin Superfamily Receptor for Cellular and Viral MHC Class I Molecules

inferredcites →https://doi.org/10.1016/s1074-7613(00)80574-9openalex-snapshot

Association of DAP12 with Activating CD94/NKG2C NK Cell Receptors

inferredcites →https://doi.org/10.1021/bi051408hopenalex-snapshot

Decoding Protein−Protein Interactions through Combinatorial Chemistry: Sequence Specificity of SHP-1, SHP-2, and SHIP SH2 Domains

inferredcites →https://doi.org/10.1038/35642openalex-snapshot

Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells

inferredcites →https://doi.org/10.1038/35869openalex-snapshot

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

inferredcites →https://doi.org/10.1038/nature03847openalex-snapshot

Licensing of natural killer cells by host major histocompatibility complex class I molecules

inferredcites →https://doi.org/10.1038/ncb919openalex-snapshot

Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation

inferredcites →https://doi.org/10.1038/ncb920openalex-snapshot

SAP couples Fyn to SLAM immune receptors

inferredcites →https://doi.org/10.1038/ni1242openalex-snapshot

Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor

inferredcites →https://doi.org/10.1038/ni1325openalex-snapshot

NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells

inferredcites →https://doi.org/10.1038/ni857openalex-snapshot

NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation

inferredcites →https://doi.org/10.1038/ni929openalex-snapshot

NKG2D-DAP10 triggers human NK cell–mediated killing via a Syk-independent regulatory pathway

inferredcites →https://doi.org/10.1038/nm.2366openalex-snapshot

Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors

inferredcites →https://doi.org/10.1038/nri1761openalex-snapshot

Immune regulation by SLAM family receptors and SAP-related adaptors

inferredcites →https://doi.org/10.1038/nri3799openalex-snapshot

Balancing natural killer cell activation through paired receptors

inferredcites →https://doi.org/10.1038/s41467-019-10335-5openalex-snapshot

Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition

inferredcites →https://doi.org/10.1038/s41590-018-0209-9openalex-snapshot

NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development

inferredcites →https://doi.org/10.1038/s41590-019-0448-4openalex-snapshot

A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44

inferredcites →https://doi.org/10.1073/pnas.072065999openalex-snapshot

Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation

inferredcites →https://doi.org/10.1073/pnas.0730640100openalex-snapshot

Transforming growth factor β1 inhibits expression of NKp30 and NKG2D receptors: Consequences for the NK-mediated killing of dendritic cells

inferredcites →https://doi.org/10.1073/pnas.1521740112openalex-snapshot

Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity

inferredcites →https://doi.org/10.1073/pnas.1814052115openalex-snapshot

CD226 regulates natural killer cell antitumor responses via phosphorylation-mediated inactivation of transcription factor FOXO1

inferredcites →https://doi.org/10.1074/jbc.273.49.32934openalex-snapshot

DAP12-mediated Signal Transduction in Natural Killer Cells

inferredcites →https://doi.org/10.1074/jbc.m401040200openalex-snapshot

The LFA-1-associated Molecule PTA-1 (CD226) on T Cells Forms a Dynamic Molecular Complex with Protein 4.1G and Human Discs Large

inferredcites →https://doi.org/10.1074/jbc.m808561200openalex-snapshot

The Traffic of the NKG2D/Dap10 Receptor Complex during Natural Killer (NK) Cell Activation

inferredcites →https://doi.org/10.1084/jem.186.12.1965openalex-snapshot

Functional Role for Syk Tyrosine Kinase in Natural Killer Cell–mediated Natural Cytotoxicity

inferredcites →https://doi.org/10.1084/jem.186.7.1129openalex-snapshot

p46, a Novel Natural Killer Cell–specific Surface Molecule That Mediates Cell Activation

inferredcites →https://doi.org/10.1084/jem.188.11.2083openalex-snapshot

2B4, the Natural Killer and T Cell Immunoglobulin Superfamily Surface Protein, Is a Ligand for CD48

inferredcites →https://doi.org/10.1084/jem.189.5.787openalex-snapshot

NKp44, A Triggering Receptor Involved in Tumor Cell Lysis by Activated Human Natural Killer Cells, Is a Novel Member of the Immunoglobulin Superfamily

inferredcites →https://doi.org/10.1084/jem.20020797openalex-snapshot

A Signal Peptide Derived from hsp60 Binds HLA-E and Interferes with CD94/NKG2A Recognition

inferredcites →https://doi.org/10.1084/jem.20030788openalex-snapshot

Identification of PVR (CD155) and Nectin-2 (CD112) as Cell Surface Ligands for the Human DNAM-1 (CD226) Activating Molecule

inferredcites →https://doi.org/10.1084/jem.20031847openalex-snapshot

Differential Requirements for Vav Proteins in DAP10- and ITAM-mediated NK Cell Cytotoxicity

inferredcites →https://doi.org/10.1084/jem.20132038openalex-snapshot

EAT-2, a SAP-like adaptor, controls NK cell activation through phospholipase Cγ, Ca++, and Erk, leading to granule polarization

inferredcites →https://doi.org/10.1084/jem.20150792openalex-snapshot

DNAM-1 controls NK cell activation via an ITT-like motif

inferredcites →https://doi.org/10.1093/intimm/dxh059openalex-snapshot

Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112)

inferredcites →https://doi.org/10.1093/intimm/dxt061openalex-snapshot

Manipulation of EAT-2 expression promotes induction of multiple beneficial regulatory and effector functions of the human innate immune system as a novel immunomodulatory strategy

inferredcites →https://doi.org/10.1111/imm.12921openalex-snapshot

Natural killer cell cytotoxicity and its regulation by inhibitory receptors

inferredcites →https://doi.org/10.1111/j.1365-2249.2004.02686.xopenalex-snapshot

Effects of prolactin and cortisol on natural killer (NK) cell surface expression and function of human natural cytotoxicity receptors (NKp46, NKp44 and NKp30)

inferredcites →https://doi.org/10.1111/j.1600-065x.1997.tb00945.xopenalex-snapshot

Specificity and function of immunoglobulin superfamily NK cell inhibitory and stimulatory receptors

inferredcites →https://doi.org/10.1111/j.1600-065x.2006.00464.xopenalex-snapshot

Natural killer cells: roundup

inferredcites →https://doi.org/10.1111/j.1600-065x.2008.00660.xopenalex-snapshot

Negative signaling by inhibitory receptors: the NK cell paradigm

inferredcites →https://doi.org/10.1111/j.1600-065x.2008.00720.xopenalex-snapshot

DAP10‐ and DAP12‐associated receptors in innate immunity

inferredcites →https://doi.org/10.1111/sji.12072openalex-snapshot

Generation of Soluble NKG 2 D Ligands: Proteolytic Cleavage, Exosome Secretion and Functional Implications

inferredcites →https://doi.org/10.1126/science.285.5428.730openalex-snapshot

An Activating Immunoreceptor Complex Formed by NKG2D and DAP10

inferredcites →https://doi.org/10.1126/scisignal.2000467openalex-snapshot

DNA-PKcs Controls an Endosomal Signaling Pathway for a Proinflammatory Response by Natural Killer Cells

inferredcites →https://doi.org/10.1126/scisignal.2002754openalex-snapshot

Complementary Phosphorylation Sites in the Adaptor Protein SLP-76 Promote Synergistic Activation of Natural Killer Cells

inferredcites →https://doi.org/10.1126/scisignal.aad6182openalex-snapshot

Dephosphorylation of the adaptor LAT and phospholipase C–γ by SHP-1 inhibits natural killer cell cytotoxicity

inferredcites →https://doi.org/10.1128/mcb.01477-07openalex-snapshot

Phosphatidylinositol 3-Kinase Activation Is Required To Form the NKG2D Immunological Synapse

inferredcites →https://doi.org/10.1128/mcb.23.17.6291-6299.2003openalex-snapshot

Vav1 Dephosphorylation by the Tyrosine Phosphatase SHP-1 as a Mechanism for Inhibition of Cellular Cytotoxicity

inferredcites →https://doi.org/10.1146/annurev.biophys.32.110601.142347openalex-snapshot

Structure and Function of Natural Killer Cell Surface Receptors

inferredcites →https://doi.org/10.1158/2326-6066.cir-15-0098openalex-snapshot

NKG2D Receptor and Its Ligands in Host Defense

inferredcites →https://doi.org/10.1182/blood-2004-09-3796openalex-snapshot

Molecular basis for positive and negative signaling by the natural killer cell receptor 2B4 (CD244)

inferredcites →https://doi.org/10.1182/blood-2005-04-1351openalex-snapshot

Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion

inferredcites →https://doi.org/10.1182/blood-2009-01-201632openalex-snapshot

Minimal requirement for induction of natural cytotoxicity and intersection of activation signals by inhibitory receptors

inferredcites →https://doi.org/10.1182/blood-2013-01-476606openalex-snapshot

Soluble ligands for NK cell receptors promote evasion of chronic lymphocytic leukemia cells from NK cell anti-tumor activity

inferredcites →https://doi.org/10.1182/blood-2013-03-489054openalex-snapshot

Identification of a cellular ligand for the natural cytotoxicity receptor NKp44

inferredcites →https://doi.org/10.1186/s12943-019-0956-8openalex-snapshot

Natural killer group 2D receptor and its ligands in cancer immune escape

inferredcites →https://doi.org/10.1189/jlb.0903428openalex-snapshot

Rat NKp46 activates natural killer cell cytotoxicity and is associated with FcɛRIγ and CD3ζ

inferredcites →https://doi.org/10.1371/journal.pone.0004503openalex-snapshot

Cellular Expression, Trafficking, and Function of Two Isoforms of Human ULBP5/RAET1G

inferredcites →https://doi.org/10.1371/journal.pone.0019245openalex-snapshot

LILRA3 Binds Both Classical and Non-Classical HLA Class I Molecules but with Reduced Affinities Compared to LILRB1/LILRB2: Structural Evidence

inferredcites →https://doi.org/10.1371/journal.pone.0059552openalex-snapshot

Novel Interaction between Proliferating Cell Nuclear Antigen and HLA I on the Surface of Tumor Cells Inhibits NK Cell Function through NKp44

inferredcites →https://doi.org/10.1371/journal.pone.0092184openalex-snapshot

Fine Specificity and Molecular Competition in SLAM Family Receptor Signalling

inferredcites →https://doi.org/10.18632/oncotarget.16688openalex-snapshot

Chromatin state dynamics during NK cell activation

inferredcites →https://doi.org/10.18632/oncotarget.7597openalex-snapshot

The human 2B4 and NTB-A receptors bind the influenza viral hemagglutinin and co-stimulate NK cell cytotoxicity

inferredcites →https://doi.org/10.2741/2735openalex-snapshot

Regulation of NK cell activity by 2B4, NTB-A and CRACC

inferredcites →https://doi.org/10.3324/haematol.2016.151555openalex-snapshot

CD244 maintains the proliferation ability of leukemia initiating cells through SHP-2/p27 kip1 signaling

inferredcites →https://doi.org/10.3389/fimmu.2012.00258openalex-snapshot

KIR2DL4 (CD158d): An activation receptor for HLA-G

inferredcites →https://doi.org/10.3389/fimmu.2013.00003openalex-snapshot

NK cell cytotoxicity mediated by 2B4 and NTB-A is dependent on SAP acting downstream of receptor phosphorylation

inferredcites →https://doi.org/10.3389/fimmu.2017.00789openalex-snapshot

Differential Requirements for Src-Family Kinases in SYK or ZAP70-Mediated SLP-76 Phosphorylation in Lymphocytes

inferredcites →https://doi.org/10.3389/fimmu.2018.00441openalex-snapshot

NKG2D: A Master Regulator of Immune Cell Responsiveness

inferredcites →https://doi.org/10.3389/fimmu.2018.02041openalex-snapshot

Targeting Checkpoint Receptors and Molecules for Therapeutic Modulation of Natural Killer Cells

inferredcites →https://doi.org/10.3389/fimmu.2018.02809openalex-snapshot

The Emerging Role of CD244 Signaling in Immune Cells of the Tumor Microenvironment

inferredcites →https://doi.org/10.3389/fimmu.2019.00909openalex-snapshot

The Natural Cytotoxicity Receptors in Health and Disease

inferredcites →https://doi.org/10.3390/cancers11060877openalex-snapshot

DNAM-1 and the TIGIT/PVRIG/TACTILE Axis: Novel Immune Checkpoints for Natural Killer Cell-Based Cancer Immunotherapy

inferredcites →https://doi.org/10.3390/cells9030753openalex-snapshot

Understanding the Synergy of NKp46 and Co-Activating Signals in Various NK Cell Subpopulations: Paving the Way for More Successful NK-Cell-Based Immunotherapy

inferredcites →https://doi.org/10.3390/ijms20153715openalex-snapshot

DNAM-1 Activating Receptor and Its Ligands: How Do Viruses Affect the NK Cell-Mediated Immune Surveillance during the Various Phases of Infection?

inferredcites →https://doi.org/10.3779/j.issn.1009-3419.2010.07.14openalex-snapshot

[Natural killer cells and cancer. Regulation by the killer cell Ig-like receptors (KIR)].

inferredcites →https://doi.org/10.4049/jimmunol.0803840openalex-snapshot

PI3K Links NKG2D Signaling to a CrkL Pathway Involved in Natural Killer Cell Adhesion, Polarity, and Granule Secretion

inferredcites →https://doi.org/10.4049/jimmunol.1002092openalex-snapshot

NKG2D Initiates Caspase-Mediated CD3ζ Degradation and Lymphocyte Receptor Impairments Associated with Human Cancer and Autoimmune Disease

inferredcites →https://doi.org/10.4049/jimmunol.1003078openalex-snapshot

HLA Class I Allelic Sequence and Conformation Regulate Leukocyte Ig-Like Receptor Binding

inferredcites →https://doi.org/10.4049/jimmunol.1102267openalex-snapshot

Proliferating Cell Nuclear Antigen Is a Novel Inhibitory Ligand for the Natural Cytotoxicity Receptor NKp44

inferredcites →https://doi.org/10.4049/jimmunol.1303070openalex-snapshot

SAP Facilitates Recruitment and Activation of LCK at NTB-A Receptors during Restimulation-Induced Cell Death

inferredcites →https://doi.org/10.4049/jimmunol.162.12.7181openalex-snapshot

CD94/NKG2-A Inhibitory Complex Blocks CD16-Triggered Syk and Extracellular Regulated Kinase Activation, Leading to Cytotoxic Function of Human NK Cells

inferredcites →https://doi.org/10.4049/jimmunol.168.10.5047openalex-snapshot

SHP-1- and Phosphotyrosine-Independent Inhibitory Signaling by a Killer Cell Ig-Like Receptor Cytoplasmic Domain in Human NK Cells

inferredcites →https://doi.org/10.4049/jimmunol.168.12.6208openalex-snapshot

KIR2DL4 (CD158d), an NK Cell-Activating Receptor with Inhibitory Potential

inferredcites →https://doi.org/10.4049/jimmunol.168.2.671openalex-snapshot

UL16-Binding Proteins, Novel MHC Class I-Related Proteins, Bind to NKG2D and Activate Multiple Signaling Pathways in Primary NK Cells

inferredcites →https://doi.org/10.4049/jimmunol.170.9.4539openalex-snapshot

Src Homology Region 2-Containing Protein Tyrosine Phosphatase-2 (SHP-2) Can Play a Direct Role in the Inhibitory Function of Killer Cell Ig-Like Receptors in Human NK Cells

inferredcites →https://doi.org/10.4049/jimmunol.1700799openalex-snapshot

Cutting Edge: NKG2D Signaling Enhances NK Cell Responses but Alone Is Insufficient To Drive Expansion during Mouse Cytomegalovirus Infection

inferredcites →https://doi.org/10.4049/jimmunol.171.3.1343openalex-snapshot

Complexes of HLA-G Protein on the Cell Surface Are Important for Leukocyte Ig-Like Receptor-1 Function

inferredcites →https://doi.org/10.4049/jimmunol.171.7.3415openalex-snapshot

KIR2DL4 Is an IL-2-Regulated NK Cell Receptor That Exhibits Limited Expression in Humans but Triggers Strong IFN-γ Production

inferredcites →https://doi.org/10.4049/jimmunol.172.12.7385openalex-snapshot

KIR2DL5 Can Inhibit Human NK Cell Activation Via Recruitment of Src Homology Region 2-Containing Protein Tyrosine Phosphatase-2 (SHP-2)

inferredcites →https://doi.org/10.4049/jimmunol.172.2.899openalex-snapshot

NKp44 Triggers NK Cell Activation through DAP12 Association That Is Not Influenced by a Putative Cytoplasmic Inhibitory Sequence

inferredcites →https://doi.org/10.4049/jimmunol.174.7.3859openalex-snapshot

Cutting Edge: KIR2DL4 Transduces Signals into Human NK Cells through Association with the Fc Receptor γ Protein

inferredcites →https://doi.org/10.4049/jimmunol.175.1.213openalex-snapshot

The Isoforms of Phospholipase C-γ Are Differentially Used by Distinct Human NK Activating Receptors

inferredcites →https://doi.org/10.4049/jimmunol.175.12.7996openalex-snapshot

The Cytotoxicity Receptor CRACC (CS-1) Recruits EAT-2 and Activates the PI3K and Phospholipase Cγ Signaling Pathways in Human NK Cells

inferredcites →https://doi.org/10.4049/jimmunol.180.12.8159openalex-snapshot

Molecular Basis of the Dual Functions of 2B4 (CD244)

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Upregulated Circulating CD4 KLRD1 T Cells Exhibit Characteristics of CD4 Cytotoxic T Lymphocytes in Systemic Lupus Erythematosus Patients

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NKG2A and circulating extracellular vesicles are key regulators of natural killer cell activity in prostate cancer after prostatectomy

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The Power of Three: Nanomaterials for Natural Killer (NK) Cell Immunoengineering Maximize Their Potency if They Exploit Multireceptor Stimulation

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Modular Droplet‐Based Microfluidic Platform for Functional Phenotypic Screening of Natural Killer Cells

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Basics in Immunology—What a Pathologist and Oncologist Should Know

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Effects of Static Magnetic Fields on the Immune System

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Arntl deficiency impairs NK cell function by reducing responsiveness to IL-15 and suppressing activation

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Antitumor effects of natural killer cells derived from gene-engineered human-induced pluripotent stem cells on hepatocellular carcinoma

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Immunomodulating functions of human leukocyte antigen-G and its role in graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

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Reactivation of natural killer cells with monoclonal antibodies in the microenvironment of malignant neoplasms

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The role of myeloid-derived suppressor cells in liver cancer

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Innate and adaptive immunity in cancer

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Control of innate immune response by biomaterial surface topography, energy, and stiffness

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Interactions between hepatic stellate cells and immune cells: Implications for liver fibrosis

inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115004openalex-snapshot

Driving natural killer cell-based cancer immunotherapy for cancer treatment: An arduous journey to promising ground

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Intrinsic and extrinsic factors determining natural killer cell fate: Phenotype and function

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Cytokine‐Induced Memory‐Like NK Cells: Emerging strategy for AML immunotherapy

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Reprogramming natural killer cells in the tumor microenvironment: Challenges and therapeutic opportunities

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P2X7R in skin diseases: Pathological mechanisms and therapeutic potential

inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e33759openalex-snapshot

Exploring the effect of NK-cell related molecules on the prognosis and tumor microenvironment of gastric cancer patients: Evidence from large sample populations

inferred← citeshttps://doi.org/10.1016/j.immuni.2026.05.007openalex-snapshot

Cholesterol metabolism in immune cells: From mechanisms to therapeutic opportunities

inferred← citeshttps://doi.org/10.1016/j.intimp.2024.111681openalex-snapshot

Anti-PD-1 therapy reverses TIGIT+CD226+NK depletion in immunotherapy resistance of hepatocellular carcinoma through PVR/TIGIT pathway

inferred← citeshttps://doi.org/10.1016/j.intimp.2026.117160openalex-snapshot

Human NKG2C+ adaptive NK cells for Cancer immunotherapy

inferred← citeshttps://doi.org/10.1016/j.jep.2024.118115openalex-snapshot

Sijunzi decoction enhances sensitivity of colon cancer cells to NK cell destruction by modulating P53 expression

inferred← citeshttps://doi.org/10.1016/j.jep.2024.118681openalex-snapshot

Upregulation of NK cell activity, cytokine expression, and NF-κB pathway by ginsenoside concentrates from Panax ginseng berries in healthy mice and macrophage cell lines

inferred← citeshttps://doi.org/10.1016/j.omto.2021.08.005openalex-snapshot

Extending traditional antibody therapies: Novel discoveries in immunotherapy and clinical applications

inferred← citeshttps://doi.org/10.1016/j.omton.2024.200870openalex-snapshot

Bulk and single-cell transcriptomics identify gene signatures of stem cell-derived NK cell donors with superior cytolytic activity

inferred← citeshttps://doi.org/10.1016/j.omton.2025.201119openalex-snapshot

Non-viral TcBuster transposon engineering of CD70-CAR natural killer cells for the treatment of osteosarcoma

inferred← citeshttps://doi.org/10.1016/j.trim.2025.102303openalex-snapshot

Natural killer cell KIR genotype and NKG2C phenotype in correlation to BKV infection following kidney transplantation

inferred← citeshttps://doi.org/10.1016/j.trre.2025.100986openalex-snapshot

The role of natural killer cells in the immune response after liver transplantation

inferred← citeshttps://doi.org/10.1016/j.yexcr.2025.114683openalex-snapshot

Chimeric antigen receptor (CAR)-NK cell therapy in gastrointestinal (GI) cancers; a new arena

inferred← citeshttps://doi.org/10.1038/s41401-026-01787-9openalex-snapshot

Nanobody-based targeted cancer therapy and immunotherapy: fear not the future

inferred← citeshttps://doi.org/10.1038/s41418-024-01396-1openalex-snapshot

127aa encoded by circSpdyA promotes FA synthesis and NK cell repression in breast cancers

inferred← citeshttps://doi.org/10.1038/s41540-024-00346-4openalex-snapshot

Integrative temporal multi-omics reveals uncoupling of transcriptome and proteome during human T cell activation

inferred← citeshttps://doi.org/10.1038/s41598-025-95211-7openalex-snapshot

Transcriptional signature of rapidly responding NK cells reveals S1P5 and CXCR4 as anti-tumor response disruptors

inferred← citeshttps://doi.org/10.1039/d3tb02557hopenalex-snapshot

Immune-cell-mediated tissue engineering strategies for peripheral nerve injury and regeneration

inferred← citeshttps://doi.org/10.1080/08820139.2026.2729083openalex-snapshot

The Expression of Notch1 and Notch2 is Up-Regulated on Natural Killer Cells by the Interaction Between NKp46 and Syndecan-1 in a Mouse Breast Cancer Model

inferred← citeshttps://doi.org/10.1080/10428194.2024.2438802openalex-snapshot

Natural killer cells: a new promising source for developing chimeric antigen receptor anti-cancer cells in hematological malignancies

inferred← citeshttps://doi.org/10.1080/19420862.2024.2433121openalex-snapshot

Agonistic anti-NKG2D antibody structure reveals unique stoichiometry and epitope compared to natural ligands

inferred← citeshttps://doi.org/10.1080/2162402x.2020.1854529openalex-snapshot

Anti-NKG2D single domain-based antibodies for the modulation of anti-tumor immune response

inferred← citeshttps://doi.org/10.1080/25785826.2025.2506260openalex-snapshot

The roles of natural killer cells in bone and arthritic disease: a narrative review

inferred← citeshttps://doi.org/10.1089/cbr.2024.0078openalex-snapshot

Development in the Study of Natural Killer Cells for Malignant Peritoneal Mesothelioma Treatment

inferred← citeshttps://doi.org/10.1093/jimmun/vkag059openalex-snapshot

HIF-1α impairs NK cell differentiation-maturation and cytotoxicity in myelodysplastic syndrome via JAK1/STAT5/SOCS2 pathway

inferred← citeshttps://doi.org/10.1093/jpp/rgag045openalex-snapshot

A novel Platycladus orientalis essential oil with functional properties: antioxidant defense, cognitive improvement, and immune enhancement for potential nutraceutical use

inferred← citeshttps://doi.org/10.1093/oncolo/oyaf410openalex-snapshot

Melanoma of unknown primary: a comprehensive review of immune-mediated pathogenesis and therapies

inferred← citeshttps://doi.org/10.1093/pcmedi/pbag020openalex-snapshot

Natural killer cells against viral infection: from basic biology to immunotherapy

inferred← citeshttps://doi.org/10.1097/hc9.0000000000000923openalex-snapshot

The dual roles of natural killer cells in liver immunity and tolerance: Implications for health and disease

inferred← citeshttps://doi.org/10.1097/ms9.0000000000003002openalex-snapshot

Exploring the potential of CAR-NK cell therapy in the management of head and neck cancer (HNC): a narrative review

inferred← citeshttps://doi.org/10.1101/2021.08.20.457155openalex-snapshot

A small molecule drug screening identifies colistin sulfate as an enhancer of Natural Killer cell cytotoxicity

inferred← citeshttps://doi.org/10.1101/2023.03.17.532022openalex-snapshot

Integrative proteomics and transcriptomics of human T-cells reveals temporal metabolic reprogramming following TCR-induced activation

inferred← citeshttps://doi.org/10.1101/2025.02.03.636324openalex-snapshot

Single-cell RNA-seq reveals altered plasma cell subsets and decreased cytotoxicity of NK cells in patients with Kawasaki disease

inferred← citeshttps://doi.org/10.1111/apm.70175openalex-snapshot

Lymphocyte Suppression and Exhaustion, Conventional, and Accelerated

inferred← citeshttps://doi.org/10.1111/imm.13464openalex-snapshot

NK‐cell exhaustion, B‐cell exhaustion and T‐cell exhaustion—the differences and similarities

inferred← citeshttps://doi.org/10.1111/sji.13106openalex-snapshot

Immunomodulatory potential of flavonoids for the treatment of autoimmune diseases and tumour

inferred← citeshttps://doi.org/10.1128/iai.00472-24openalex-snapshot

Infection-induced trained immunity: a twist in paradigm of innate host defense and generation of immunological memory

inferred← citeshttps://doi.org/10.1128/mbio.01724-26openalex-snapshot

Fc-engineered broadly neutralizing antibodies overcome cytokine-induced CD16 cleavage to drive potent ADCC against diverse HIV-1 strains

inferred← citeshttps://doi.org/10.1136/jcp-2025-210074openalex-snapshot

The fifth edition of the WHO classification of mature T cell, NK cell and stroma-derived neoplasms

inferred← citeshttps://doi.org/10.1136/jitc-2024-008959openalex-snapshot

Enhanced IL-15-mediated NK cell activation and proliferation by an ADAM17 function-blocking antibody involves CD16A, CD137, and accessory cells

inferred← citeshttps://doi.org/10.1155/jimr/3833044openalex-snapshot

Natural Killer Cells in Uterine Adenomyosis: Immunological Mechanisms and Therapeutic Perspectives

inferred← citeshttps://doi.org/10.1177/03946320231215219openalex-snapshot

Bibliometric and visual analyses of trends in the field of T cell exhaustion research: Findings from 2000 to 2022

inferred← citeshttps://doi.org/10.1186/s12885-023-11209-2openalex-snapshot

TUBA1C is a potential new prognostic biomarker and promotes bladder urothelial carcinoma progression by regulating the cell cycle

inferred← citeshttps://doi.org/10.1186/s12964-023-01428-2openalex-snapshot

The role of exhausted natural killer cells in the immunopathogenesis and treatment of leukemia

inferred← citeshttps://doi.org/10.1186/s12964-025-02443-1openalex-snapshot

CAR-NK cell therapy in multiple myeloma: from preclinical and clinical landscape to joining the force for treatment strategies optimization

inferred← citeshttps://doi.org/10.1186/s12967-026-08400-xopenalex-snapshot

CD45 as a multifunctional target in immune regulation and therapeutic delivery

inferred← citeshttps://doi.org/10.1186/s13287-025-04352-zopenalex-snapshot

Glioma stem cells: drivers of tumor progression and recurrence

inferred← citeshttps://doi.org/10.1186/s40001-025-03477-4openalex-snapshot

Identification of coagulation-related hub genes in ischemic stroke based on bioinformatics integration analysis and investigation of their immune regulatory mechanisms

inferred← citeshttps://doi.org/10.1186/s40164-024-00561-zopenalex-snapshot

Natural killer cell-based cancer immunotherapy: from basics to clinical trials

inferred← citeshttps://doi.org/10.1186/s40635-025-00829-6openalex-snapshot

Dynamic changes of natural killer cell immunophenotypes and receptors according to the mortality in the intra-abdominal murine sepsis model

inferred← citeshttps://doi.org/10.12677/acm.2023.13102315openalex-snapshot

Advances in the Study of Uterine Natural Killer Cells and Their Relationship with Pregnancy Complications

inferred← citeshttps://doi.org/10.1371/journal.ppat.1011242openalex-snapshot

Inhibition of hepatic natural killer cell function via the TIGIT receptor in schistosomiasis-induced liver fibrosis

inferred← citeshttps://doi.org/10.17760/d20416548openalex-snapshot

Targeted delivery of low-dose liposomal STING agonist to CD103+ dendritic cells in tumor immunotherapy

inferred← citeshttps://doi.org/10.20935/acadonco7986openalex-snapshot

Allogeneic supercharged natural killer cells: an innovative approach for hematologic cancers

inferred← citeshttps://doi.org/10.21203/rs.3.rs-1787033/v1openalex-snapshot

Repurposing of Spironolactone Towards Upregulation of the Expression of NKG2D Ligands in Metastatic Osteosarcoma Mouse Model

inferred← citeshttps://doi.org/10.21203/rs.3.rs-3474573/v1openalex-snapshot

Investigating Potential Drug Targets in Intracranial Aneurysms through Mendelian Randomization and Transcriptome Analyses

inferred← citeshttps://doi.org/10.21203/rs.3.rs-9692790/v1openalex-snapshot

DAP12 enhances CAR-NK cell function via NR4A2-mediated upregulation of 4-1BB expression

inferred← citeshttps://doi.org/10.2147/itt.s545646openalex-snapshot

Research Progress of Natural Killer Cells in Hashimoto’s Thyroiditis

inferred← citeshttps://doi.org/10.22038/ijbms.2023.68653.14969openalex-snapshot

Regulatory NK cells in autoimmune disease.

inferred← citeshttps://doi.org/10.29413/abs.2023-8.6.4openalex-snapshot

Influence of alpha-glutamil-tryptophan on the background and induced activity of factors of adaptive immunity for prevention

inferred← citeshttps://doi.org/10.3389/fcell.2025.1532491openalex-snapshot

NK cells in renal cell carcinoma and its implications for CAR-NK therapy

inferred← citeshttps://doi.org/10.3389/fcimb.2023.1126350openalex-snapshot

Systematic analysis of lysine crotonylation in human macrophages responding to MRSA infection

inferred← citeshttps://doi.org/10.3389/fcvm.2025.1625064openalex-snapshot

Identification of arachidonic acid metabolism-related diagnostic markers in heart failure based on bioinformatics analysis and machine learning

inferred← citeshttps://doi.org/10.3389/fimmu.2021.650200openalex-snapshot

IL-10-Producing ILCs: Molecular Mechanisms and Disease Relevance

inferred← citeshttps://doi.org/10.3389/fimmu.2021.734551openalex-snapshot

NK Cells in a Tug-of-War With Cancer: The Roles of Transcription Factors and Cytoskeleton

inferred← citeshttps://doi.org/10.3389/fimmu.2021.816499openalex-snapshot

Natural Killer Cells in the Malignant Niche of Multiple Myeloma

inferred← citeshttps://doi.org/10.3389/fimmu.2022.822298openalex-snapshot

Taking Lessons from CAR-T Cells and Going Beyond: Tailoring Design and Signaling for CAR-NK Cells in Cancer Therapy

inferred← citeshttps://doi.org/10.3389/fimmu.2022.842831openalex-snapshot

Negative Regulation and Protective Function of Natural Killer Cells in HIV Infection: Two Sides of a Coin

inferred← citeshttps://doi.org/10.3389/fimmu.2022.871106openalex-snapshot

Locked and Loaded: Mechanisms Regulating Natural Killer Cell Lytic Granule Biogenesis and Release

inferred← citeshttps://doi.org/10.3389/fimmu.2023.1101918openalex-snapshot

Natural killer cells in sepsis: Friends or foes?

inferred← citeshttps://doi.org/10.3389/fimmu.2023.1192907openalex-snapshot

Understanding NK cell biology for harnessing NK cell therapies: targeting cancer and beyond

inferred← citeshttps://doi.org/10.3389/fimmu.2024.1297994openalex-snapshot

Epstein-Barr virus: the mastermind of immune chaos

inferred← citeshttps://doi.org/10.3389/fimmu.2024.1390498openalex-snapshot

Antitumor activity of genetically engineered NK-cells in non-hematological solid tumor: a comprehensive review

inferred← citeshttps://doi.org/10.3389/fimmu.2024.1442673openalex-snapshot

Natural killer cells: a future star for immunotherapy of head and neck squamous cell carcinoma

inferred← citeshttps://doi.org/10.3389/fimmu.2025.1511616openalex-snapshot

Advances in the role of NK cells in MDS immune dysfunction and antitumor research

inferred← citeshttps://doi.org/10.3389/fimmu.2025.1558701openalex-snapshot

Nanomaterial assisted natural killer cell therapy

inferred← citeshttps://doi.org/10.3389/fimmu.2025.1563635openalex-snapshot

Immune microenvironment in intervertebral disc degeneration: pathophysiology and therapeutic potential

inferred← citeshttps://doi.org/10.3389/fimmu.2025.1563872openalex-snapshot

Two major human phenotypes of MICA molecules and their differential activation to NK cells via NKG2D receptor

inferred← citeshttps://doi.org/10.3389/fimmu.2025.1572676openalex-snapshot

Combined treatment with anti-PSMA antibody and human peripheral blood-derived NK cells for castration-resistant prostate cancer

inferred← citeshttps://doi.org/10.3389/fimmu.2025.1621885openalex-snapshot

NK cell-based immunotherapy strategies for myeloid leukemia

inferred← citeshttps://doi.org/10.3389/fimmu.2025.1715827openalex-snapshot

A ligand-centered framework for γδ T cell activation in colorectal cancer revealed by single-cell and transformer-based perturbation

inferred← citeshttps://doi.org/10.3389/fimmu.2026.1810902openalex-snapshot

Chronic viral infections and their role in shaping the tumor immune microenvironment

inferred← citeshttps://doi.org/10.3389/fimmu.2026.1917564openalex-snapshot

Research progress on the role and dysregulation of NK cells in anti-tuberculosis immunity

inferred← citeshttps://doi.org/10.3389/fimmu.2026.1961240openalex-snapshot

Metabolic reprogramming of NK cells in chronic brucellar arthritis: role of the HIF-1α/mTOR axis

inferred← citeshttps://doi.org/10.3389/fonc.2022.1077436openalex-snapshot

Current state of NK cell-mediated immunotherapy in chronic lymphocytic leukemia

inferred← citeshttps://doi.org/10.3389/fonc.2024.1502270openalex-snapshot

Reversing NK cell exhaustion: a novel strategy combining immune checkpoint blockade with drug sensitivity enhancement in the treatment of hepatocellular carcinoma

inferred← citeshttps://doi.org/10.3390/ani15162454openalex-snapshot

Comparative Transcriptomic Analysis of the Liver and Spleen in Ussuri Catfish (Pseudobagrus ussuriensis) Challenged with Polyriboinosinic Polyribocytidylic Acid (Poly(I:C))

inferred← citeshttps://doi.org/10.3390/biom12010004openalex-snapshot

Role of IL-10-Producing Natural Killer Cells in the Regulatory Mechanisms of Inflammation during Systemic Infection

inferred← citeshttps://doi.org/10.3390/biom16091302openalex-snapshot

NKR-P1A/CD161: A Multifunctional Immune Receptor at the Crossroads of Antitumor Immunity

inferred← citeshttps://doi.org/10.3390/biomedicines13061412openalex-snapshot

Altered Expression of NK Receptors in Racially/Ethnically Diverse and Risk-of-Relapse Pediatric Acute Lymphoblastic Leukemia Patients

inferred← citeshttps://doi.org/10.3390/cancers13184722openalex-snapshot

Adoptive NK Cell Therapy: A Promising Treatment Prospect for Metastatic Melanoma

inferred← citeshttps://doi.org/10.3390/cancers14122832openalex-snapshot

A New Functional Screening Platform Identifies Colistin Sulfate as an Enhancer of Natural Killer Cell Cytotoxicity

inferred← citeshttps://doi.org/10.3390/cancers15123225openalex-snapshot

Enhancement of the Anticancer Ability of Natural Killer Cells through Allogeneic Mitochondrial Transfer

inferred← citeshttps://doi.org/10.3390/cancers16142608openalex-snapshot

The Spectrum of CAR Cellular Effectors: Modes of Action in Anti-Tumor Immunity

inferred← citeshttps://doi.org/10.3390/cancers17182946openalex-snapshot

Influence of Genetic, Dietary, and Environmental Factors on Natural Killer (NK) Cell Biology and Function: Interplay Between NK Cell Activity and Cancer Onset or Progression

inferred← citeshttps://doi.org/10.3390/cancers17233862openalex-snapshot

Natural Killer (NK) Cell-Based Therapies Have the Potential to Treat Ovarian Cancer Effectively by Targeting Diverse Tumor Populations and Reducing the Risk of Recurrence

inferred← citeshttps://doi.org/10.3390/cells12232750openalex-snapshot

CAR NK Cell Therapy for the Treatment of Metastatic Melanoma: Potential & Prospects

inferred← citeshttps://doi.org/10.3390/cells13060530openalex-snapshot

Autologous T-Cell-Free Antigen Presentation System Unveils hCMV-Specific NK Cell Response

inferred← citeshttps://doi.org/10.3390/cells13131148openalex-snapshot

A Critical Role of Culture Medium Selection in Maximizing the Purity and Expansion of Natural Killer Cells

inferred← citeshttps://doi.org/10.3390/cimb46010011openalex-snapshot

Antitumor Immunity: Role of NK Cells and Extracellular Vesicles in Cancer Immunotherapy

inferred← citeshttps://doi.org/10.3390/cimb48060642openalex-snapshot

Metformin as an Innate Immune Modulator: Metabolic and Epigenetic Reprogramming of Innate Immune Cells and Therapeutic Implications

inferred← citeshttps://doi.org/10.3390/foods12101937openalex-snapshot

Hydroxytyrosol and Arginine as Antioxidant, Anti-Inflammatory and Immunostimulant Dietary Supplements for COVID-19 and Long COVID

inferred← citeshttps://doi.org/10.3390/genes16101193openalex-snapshot

Genetic Variability in NKG2 Receptors and Their Ligands: Associations with SARS-CoV-2 Infection and COVID-19 Severity

inferred← citeshttps://doi.org/10.3390/ijms251910326openalex-snapshot

Harnessing B7-H6 for Anticancer Immunotherapy: Expression, Pathways, and Therapeutic Strategies

inferred← citeshttps://doi.org/10.3390/immuno1030011openalex-snapshot

A Brief Analysis of Tissue-Resident NK Cells in Pregnancy and Endometrial Diseases: The Importance of Pharmacologic Modulation

inferred← citeshttps://doi.org/10.3390/immuno2010005openalex-snapshot

Overview of Memory NK Cells in Viral Infections: Possible Role in SARS-CoV-2 Infection

inferred← citeshttps://doi.org/10.34172/bma.10openalex-snapshot

Therapeutic effects of NK cell-derived EVs on cancer: Current advances and future treatment strategies

inferred← citeshttps://doi.org/10.3724/zdxbyxb-2025-0692openalex-snapshot

Research progress of the ULBP-NKG2D axis in autoimmune diseases

inferred← citeshttps://doi.org/10.3892/mmr.2022.12724openalex-snapshot

Crosstalk between NK cells and hepatic stellate cells in liver fibrosis (Review)

inferred← citeshttps://doi.org/10.5483/bmbrep.2023-0044openalex-snapshot

Vorinostat-induced acetylation of RUNX3 reshapes transcriptional profile through long-range enhancer-promoter interactions in natural killer cells

inferred← citeshttps://doi.org/10.6084/m9.figshare.26607865openalex-snapshot

Additional file 1 of TUBA1C is a potential new prognostic biomarker and promotes bladder urothelial carcinoma progression by regulating the cell cycle

inferred← citeshttps://doi.org/10.6084/m9.figshare.26607868openalex-snapshot

Additional file 2 of TUBA1C is a potential new prognostic biomarker and promotes bladder urothelial carcinoma progression by regulating the cell cycle

inferred← citeshttps://doi.org/10.70675/52689792z384fz4d7dz8610zace0360b6d76openalex-snapshot

Contribution à l'étude des fonctions anti-tumorales des cellules Natural Killer (NK) : Implication en greffe de cellules souches hématopoïétiques et dans le contexte des Immunothérapies

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