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RNA-Seq Profiling to Investigate the Mechanism of Qishen Granules on Regulating Mitochondrial Energy Metabolism of Heart Failure in Rats

https://doi.org/10.1155/2021/5779307

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Prevalence of Heart Failure and Left Ventricular Dysfunction in China: The China Hypertension Survey, 2012–2015

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Measurement of mRNA abundance using RNA-seq data: RPKM measure is inconsistent among samples

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Qishen Granule alleviates endoplasmic reticulum stress-induced myocardial apoptosis through IRE-1-CRYAB pathway in myocardial ischemia

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Songorine promotes cardiac mitochondrial biogenesis via Nrf2 induction during sepsis

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Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1

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The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

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Qishen granules inhibit myocardial inflammation injury through regulating arachidonic acid metabolism

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Regulation of mitochondrial biogenesis

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Thioredoxin1 Upregulates Mitochondrial Proteins Related to Oxidative Phosphorylation and TCA Cycle in the Heart

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PGC-1α Regulates Expression of Myocardial Mitochondrial Antioxidants and Myocardial Oxidative Stress After Chronic Systolic Overload

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Transcriptional control of mitochondrial biogenesis: the central role of PGC-1

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Mitochondrial transcription factor A regulates mtDNA copy number in mammals

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Mitochondrial biogenesis: An update

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PGC‐1α protects from myocardial ischaemia‐reperfusion injury by regulating mitonuclear communication

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Replication and Transcription of Mammalian Mitochondrial Dna

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Preconditioning: The Mitochondrial Connection

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Myocardial Substrate Metabolism in the Normal and Failing Heart

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Effect of QSKL on MAPK and RhoA Pathways in a Rat Model of Heart Failure

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Antiapoptosis and Antifibrosis Effects of Qishen Granules on Heart Failure Rats via Hippo Pathway

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PGC-1 α , Inflammation, and Oxidative Stress: An Integrative View in Metabolism

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Wenxin Granule Ameliorates Hypoxia/Reoxygenation-Induced Oxidative Stress in Mitochondria via the PKC-δ/NOX2/ROS Pathway in H9c2 Cells

inferredcites →https://doi.org/10.1161/circulationaha.119.040551openalex-snapshot

Unlocking the Secrets of Mitochondria in the Cardiovascular System

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Impaired expression of NADH dehydrogenase subunit 1 and PPARγ coactivator-1 in skeletal muscle of ZDF rats

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Nuclear Control of Respiratory Chain Expression by Nuclear Respiratory Factors and PGC‐1‐Related Coactivator

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Qishenyiqi Protects Ligation-Induced Left Ventricular Remodeling by Attenuating Inflammation and Fibrosis via STAT3 and NF-κB Signaling Pathway

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A Molecular Approach to Mitophagy and Mitochondrial Dynamics.

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Transcriptomics: a Sword to Cut the Gordian knot of Traditional Chinese Medicine

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Protection against ischemia-induced ventricular arrhythmias and myocardial dysfunction conferred by preconditioning in the rat heart: involvement of mitochondrial KATP channels and reactive oxygen species

inferredcites →https://doi.org/10.3389/fphar.2018.00514openalex-snapshot

Integration of Metabonomics and Transcriptomics Reveals the Therapeutic Effects and Mechanisms of Baoyuan Decoction for Myocardial Ischemia

inferredcites →https://doi.org/10.3389/fphar.2018.01414openalex-snapshot

Pro-angiogenic Role of Danqi Pill Through Activating Fatty Acids Oxidation Pathway Against Coronary Artery Disease

inferredcites →https://doi.org/10.3389/fphar.2019.01399openalex-snapshot

Qishen Granule Improved Cardiac Remodeling via Balancing M1 and M2 Macrophages

inferredcites →https://doi.org/10.3389/fphar.2020.00458openalex-snapshot

Danqi Pill Protects Against Heart Failure Post-Acute Myocardial Infarction via HIF-1α/PGC-1α Mediated Glucose Metabolism Pathway

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Changes in PGC‐1α/SIRT1 Signaling Impact on Mitochondrial Homeostasis in Amyloid-Beta Peptide Toxicity Model

inferredcites →https://doi.org/10.3390/ijms22020614openalex-snapshot

Mitochondrial Dysfunction and Heart Disease: Critical Appraisal of an Overlooked Association

inferredcites →https://doi.org/10.3390/molecules23071829openalex-snapshot

Decomposing the Mechanism of Qishen Granules in the Treatment of Heart Failure by a Quantitative Pathway Analysis Method

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Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure

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Effect of TFAM on ATP content in tachypacing primary cultured cardiomyocytes and atrial fibrillation patients

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Hongqi Shenmai Decoction ameliorates post–myocardial infarction heart failure by preserving mitochondrial cardiolipin homeostasis via attenuation of EGFR/JAK2–STAT3 signaling

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Molecular mechanisms of sacubitril/valsartan in cardiac remodeling

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