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Overexpression and Amplification of c-myc during Progression of Human Colorectal Cancer

https://doi.org/10.1159/000227619
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inferred← citeshttps://doi.org/10.2139/ssrn.4651632openalex-extracted
Synthesis, Molecular Docking, and Anticancer Effect of Newly Synthesized 2-(Thiophen-2-Yl)-1 H-Indole Derivatives: Suppression of HCT-116 Cell Proliferation, Cell Cycle Arrest and Downregulation of MiR-25, C-Myc and Il-6
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Cenp-F gene amplification and overexpression in head and neck squamous cell carcinomas
inferred← citeshttps://doi.org/10.1002/btm2.10363openalex-snapshot
Splice‐switch oligonucleotide‐based combinatorial platform prioritizes synthetic lethal targets CHK1 and BRD4 against MYC ‐driven hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1002/chem.202201497openalex-snapshot
Gaining Insights on the Interactions of a Class of Decorated (2‐([2,2′‐Bipyridin]‐6‐yl)phenyl)platinum Compounds with c‐Myc Oncogene Promoter G‐Quadruplex and Other DNA Structures
inferred← citeshttps://doi.org/10.1002/gcc.20378openalex-snapshot
Mutations in the MYB intron I regulatory sequence increase transcription in colon cancers
inferred← citeshttps://doi.org/10.1002/mnfr.202200028openalex-snapshot
Butyrate Drives Metabolic Rewiring and Epigenetic Reprogramming in Human Colon Cancer Cells
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Identification of Potential c‐myc Inhibitors for Colorectal Cancer from Rice Husk: An Analytical and Computational Approach
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Construction of Preferential cDNA Microarray Specialized for Human Colorectal Carcinoma: Molecular Sketch of Colorectal Cancer
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Interplay Between Transcription Factors and MicroRNAs Regulating Epithelial-Mesenchymal Transitions in Colorectal Cancer
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Transcription Factors and Colorectal Cancer: An Overview
inferred← citeshttps://doi.org/10.1007/978-981-16-2629-6_9openalex-snapshot
Cytotoxic Activity of Raphanus sativus Linn. on Selected Cancer Cell Lines and Mechanistic Pathways Predicted Through Mathematical Modeling
inferred← citeshttps://doi.org/10.1007/s00018-021-04093-1openalex-snapshot
Global analysis of RNA-binding proteins identifies a positive feedback loop between LARP1 and MYC that promotes tumorigenesis
inferred← citeshttps://doi.org/10.1007/s10585-015-9749-7openalex-snapshot
Genomic gain of the PRL-3 gene may represent poor prognosis of primary colorectal cancer, and associate with liver metastasis
inferred← citeshttps://doi.org/10.1007/s12079-021-00612-8openalex-snapshot
Identification of key regulators associated with colon cancer prognosis and pathogenesis
inferred← citeshttps://doi.org/10.1007/s12094-006-0181-yopenalex-snapshot
Lack of correlation between DNA copy number and mRNA expression levels ofc-myc in γ-radiation-induced mouse thymic lymphomas by using quantitative real-time PCR
inferred← citeshttps://doi.org/10.1007/s12094-022-02910-yopenalex-snapshot
Significant position of C-myc in colorectal cancer: a promising therapeutic target
inferred← citeshttps://doi.org/10.1007/s13277-014-1713-7openalex-snapshot
Genetic unraveling of colorectal cancer
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Exploring glycolytic adaptations in cancer cells
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Molecular characterization of circadian gene expression and its correlation with survival percentage in colorectal cancer patients
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Proteomic profiling of tear fluid as a promising non-invasive screening test for colon cancer
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Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain
inferred← citeshttps://doi.org/10.1016/j.bmcl.2020.127480openalex-snapshot
Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors
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An integrated study on TFs and miRNAs in colorectal cancer metastasis and evaluation of three co-regulated candidate genes as prognostic markers
inferred← citeshttps://doi.org/10.1016/j.humgen.2025.201447openalex-snapshot
Unravelling colorectal cancer mechanisms: Insights from a regulatory network of ncRNAs, TFs, and mutated genes
inferred← citeshttps://doi.org/10.1016/j.humpath.2004.06.012openalex-snapshot
High-throughput tissue microarray analysis of c-myc activation in chronic liver diseases and hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1016/j.semcancer.2017.08.009openalex-snapshot
FoxM1: Repurposing an oncogene as a biomarker
inferred← citeshttps://doi.org/10.1016/s0003-2697(02)00311-1openalex-snapshot
Quantitative real-time reverse transcription polymerase chain reaction: normalization to rRNA or single housekeeping genes is inappropriate for human tissue biopsies
inferred← citeshttps://doi.org/10.1021/acs.jproteome.9b00119openalex-snapshot
Targeted Quantitative Kinome Analysis Identifies PRPS2 as a Promoter for Colorectal Cancer Metastasis
inferred← citeshttps://doi.org/10.1038/s41388-021-02084-xopenalex-snapshot
MiR-138 is a potent regulator of the heterogenous MYC transcript population in cancers
inferred← citeshttps://doi.org/10.1038/s41419-020-03095-4openalex-snapshot
The long noncoding RNA LUCAT1 promotes colorectal cancer cell proliferation by antagonizing Nucleolin to regulate MYC expression
inferred← citeshttps://doi.org/10.1038/s41597-021-00998-5openalex-snapshot
A merged microarray meta-dataset for transcriptionally profiling colorectal neoplasm formation and progression
inferred← citeshttps://doi.org/10.1038/s41598-024-68815-8openalex-snapshot
Evaluation of newly synthesized 2-(thiophen-2-yl)-1H-indole derivatives as anticancer agents against HCT-116 cell proliferation via cell cycle arrest and down regulation of miR-25
inferred← citeshttps://doi.org/10.1038/sj.onc.1202746openalex-snapshot
MYC oncogenes and human neoplastic disease
inferred← citeshttps://doi.org/10.1093/jjco/hyz210openalex-snapshot
The prognostic role of c-MYC amplification in schistosomiasis-associated colorectal cancer
inferred← citeshttps://doi.org/10.1093/jnci/dju505openalex-snapshot
Role of MYC-Regulated Long Noncoding RNAs in Cell Cycle Regulation and Tumorigenesis
inferred← citeshttps://doi.org/10.1111/cas.13391openalex-snapshot
Japanese genome‐wide association study identifies a significant colorectal cancer susceptibility locus at chromosome 10p14
inferred← citeshttps://doi.org/10.1111/j.1745-7270.2008.00405.xopenalex-snapshot
Zinc finger protein 278, a potential oncogene in human colorectal cancer
inferred← citeshttps://doi.org/10.1136/gutjnl-2020-322835openalex-snapshot
Chromatin state dynamics confers specific therapeutic strategies in enhancer subtypes of colorectal cancer
inferred← citeshttps://doi.org/10.1155/2005/401607openalex-snapshot
DNA Copy Number Changes at 8q11–24 in Metastasized Colorectal Cancer
inferred← citeshttps://doi.org/10.1159/000012109openalex-snapshot
Prognostic Significance of Nuclear Accumulation of c-myc and mdm2 Proteins in Synovial Sarcoma of the Extremities
inferred← citeshttps://doi.org/10.1159/000080063openalex-snapshot
Expression of c-myc mRNA in Hepatocellular Carcinomas, Noncancerous Livers, and Normal Livers
inferred← citeshttps://doi.org/10.1159/000510253openalex-snapshot
SNPs in Sites for DNA Methylation, Transcription Factor Binding, and miRNA Targets Leading to Allele-Specific Gene Expression and Contributing to Complex Disease Risk: A Systematic Review
inferred← citeshttps://doi.org/10.1186/1476-4598-9-249openalex-snapshot
Molecular detection, quantification, and isolation of Streptococcus gallolyticus bacteria colonizing colorectal tumors: inflammation-driven potential of carcinogenesis via IL-1, COX-2, and IL-8
inferred← citeshttps://doi.org/10.1186/s12881-019-0867-yopenalex-snapshot
Novel reference genes in colorectal cancer identify a distinct subset of high stage tumors and their associated histologically normal colonic tissues
inferred← citeshttps://doi.org/10.1186/s12885-016-2303-4openalex-snapshot
Comparative analysis of copy number variations in ulcerative colitis associated and sporadic colorectal neoplasia
inferred← citeshttps://doi.org/10.1186/s12885-016-2770-7openalex-snapshot
Favorable prognosis in colorectal cancer patients with co-expression of c-MYC and ß-catenin
inferred← citeshttps://doi.org/10.1186/s13046-023-02678-1openalex-snapshot
MYC drives platinum resistant SCLC that is overcome by the dual PI3K-HDAC inhibitor fimepinostat
inferred← citeshttps://doi.org/10.1245/s10434-013-3468-6openalex-snapshot
Allelic Imbalance at an 8q24 Oncogenic SNP is Involved in Activating MYC in Human Colorectal Cancer
inferred← citeshttps://doi.org/10.1371/journal.pone.0139727openalex-snapshot
c-MYC Copy-Number Gain Is an Independent Prognostic Factor in Patients with Colorectal Cancer
inferred← citeshttps://doi.org/10.15283/ijsc22188openalex-snapshot
Alterations and Co-Occurrence of C-MYC, N-MYC, and L-MYC Expression are Related to Clinical Outcomes in Various Cancers
inferred← citeshttps://doi.org/10.18632/oncotarget.23414openalex-snapshot
Modified miR-15a has therapeutic potential for improving treatment of advanced stage colorectal cancer through inhibition of BCL2, BMI1, YAP1 and DCLK1
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3572954/v1openalex-snapshot
Synthesis, molecular docking, and anticancer effect of newly synthesized 2- (thiophen-2-yl)-1H-indole derivatives: suppression of HCT-116 Cell proliferation, cell cycle arrest and downregulation of miR-25, C-Myc and IL-6
inferred← citeshttps://doi.org/10.2147/ott.s278013openalex-snapshot
Progress in Understanding the IL-6/STAT3 Pathway in Colorectal Cancer
inferred← citeshttps://doi.org/10.21873/anticanres.14649openalex-snapshot
Overexpression of Pyruvate Carboxylase Is Correlated With Colorectal Cancer Progression and Supports Growth of Invasive Colon Cancer HT-29 Cell Line
inferred← citeshttps://doi.org/10.2217/bmm-2019-0189openalex-snapshot
A Candidate Intronic CYP24A1 Gene Variant Affects the Risk of Colorectal Cancer
inferred← citeshttps://doi.org/10.3389/fonc.2025.1680561openalex-snapshot
ZFP161 promotes colorectal cancer progression by transcriptionally activating c-MYC
inferred← citeshttps://doi.org/10.3390/cancers14112648openalex-snapshot
Gallic Acid: A Natural Phenolic Compound Exerting Antitumoral Activities in Colorectal Cancer via Interaction with G-Quadruplexes
inferred← citeshttps://doi.org/10.3390/cells8121634openalex-snapshot
The Butterfly Effect of RNA Alterations on Transcriptomic Equilibrium
inferred← citeshttps://doi.org/10.3390/ijms22041837openalex-snapshot
Whole Exome Sequencing Identifies APCDD1 and HDAC5 Genes as Potentially Cancer Predisposing in Familial Colorectal Cancer
inferred← citeshttps://doi.org/10.3390/ijms24065876openalex-snapshot
Overexpression and Role of HHLA2, a Novel Immune Checkpoint, in Colorectal Cancer
inferred← citeshttps://doi.org/10.3390/ijms25010043openalex-snapshot
A Phase II Exploratory Study to Identify Biomarkers Predictive of Clinical Response to Regorafenib in Patients with Metastatic Colorectal Cancer Who Have Failed First-Line Therapy
inferred← citeshttps://doi.org/10.3390/ijms26094300openalex-snapshot
Active Substances from the Micro-Immunotherapy Medicine 2LC1® Show In Vitro Anti-Cancer Properties in Colon, Prostate, and Breast Cancer Models and Immune-Enhancing Capabilities in Human Macrophages
inferred← citeshttps://doi.org/10.3390/nu13114056openalex-snapshot
Clinically Relevant Genes and Proteins Modulated by Tocotrienols in Human Colon Cancer Cell Lines: Systematic Scoping Review
inferred← citeshttps://doi.org/10.3748/wjg.13.6581openalex-snapshot
ShRNA-mediated gene silencing of β-catenin inhibits growth of human colon cancer cells
inferred← citeshttps://doi.org/10.3892/ijo.2023.5581openalex-snapshot
Tripartite motif containing 33 demonstrated anticancer effect by degrading c‑Myc: Limitation of glutamine metabolism and proliferation in endometrial carcinoma cells
inferred← citeshttps://doi.org/10.5603/4644openalex-snapshot
K-RAS point mutation, and amplification of C-MYC and C-ERBB2 in colon adenocarcinoma.
inferred← citeshttps://doi.org/10.6084/m9.figshare.26584899openalex-snapshot
Additional file 1 of MYC drives platinum resistant SCLC that is overcome by the dual PI3K-HDAC inhibitor fimepinostat
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