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PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/j.coi.2007.06.004openalex-snapshot
CD8 T cell dysfunction during chronic viral infection
inferredcites →https://doi.org/10.1016/j.immuni.2007.05.016openalex-snapshot
Programmed Death-1 Ligand 1 Interacts Specifically with the B7-1 Costimulatory Molecule to Inhibit T Cell Responses
inferredcites →https://doi.org/10.1016/s1074-7613(00)80470-7openalex-snapshot
Counting Antigen-Specific CD8 T Cells: A Reevaluation of Bystander Activation during Viral Infection
inferredcites →https://doi.org/10.1038/nature04444openalex-snapshot
Restoring function in exhausted CD8 T cells during chronic viral infection
inferredcites →https://doi.org/10.1038/nature05115openalex-snapshot
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
inferredcites →https://doi.org/10.1038/ni1165openalex-snapshot
Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4
inferredcites →https://doi.org/10.1038/ni1443openalex-snapshot
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
inferredcites →https://doi.org/10.1038/nm1482openalex-snapshot
Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction
inferredcites →https://doi.org/10.1073/pnas.0307252101openalex-snapshot
PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells
inferredcites →https://doi.org/10.1073/pnas.0702579104openalex-snapshot
Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection
inferredcites →https://doi.org/10.1073/pnas.0801497105openalex-snapshot
Selective expansion of a subset of exhausted CD8 T cells by αPD-L1 blockade
inferredcites →https://doi.org/10.1073/pnas.0809818106openalex-snapshot
High antigen levels are the cause of T cell exhaustion during chronic viral infection
inferredcites →https://doi.org/10.1084/jem.160.2.521openalex-snapshot
Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence.
inferredcites →https://doi.org/10.1084/jem.185.3.517openalex-snapshot
Virus-induced Transient Bone Marrow Aplasia: Major Role of Interferon-α/β during Acute Infection with the Noncytopathic Lymphocytic Choriomeningitis Virus
inferredcites →https://doi.org/10.1084/jem.187.11.1903openalex-snapshot
Aplastic Anemia Rescued by Exhaustion of Cytokine-secreting CD8+ T Cells in Persistent Infection with Lymphocytic Choriomeningitis Virus
inferredcites →https://doi.org/10.1084/jem.187.9.1383openalex-snapshot
Induction and Exhaustion of Lymphocytic Choriomeningitis Virus–specific Cytotoxic T Lymphocytes Visualized Using Soluble Tetrameric Major Histocompatibility Complex Class I–Peptide Complexes
inferredcites →https://doi.org/10.1084/jem.188.12.2205openalex-snapshot
Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function
inferredcites →https://doi.org/10.1084/jem.192.9.1249openalex-snapshot
Immunosuppression and Resultant Viral Persistence by Specific Viral Targeting of Dendritic Cells
inferredcites →https://doi.org/10.1084/jem.20022235openalex-snapshot
PD-1 Inhibits Antiviral Immunity at the Effector Phase in the Liver
inferredcites →https://doi.org/10.1084/jem.20051776openalex-snapshot
Tissue expression of PD-L1 mediates peripheral T cell tolerance
inferredcites →https://doi.org/10.1084/jem.20061496openalex-snapshot
PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection
inferredcites →https://doi.org/10.1084/jem.20090847openalex-snapshot
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
inferredcites →https://doi.org/10.1086/529379openalex-snapshot
The Role of Regulatory T Cells in Chronic and Acute Viral Infections
inferredcites →https://doi.org/10.1097/00000478-199512000-00007openalex-snapshot
An Update on Terminology and Reporting
inferredcites →https://doi.org/10.1128/jvi.77.8.4911-4927.2003openalex-snapshot
Viral Persistence Alters CD8 T-Cell Immunodominance and Tissue Distribution and Results in Distinct Stages of Functional Impairment
inferredcites →https://doi.org/10.1172/jci36604openalex-snapshot
PD-L1 negatively regulates CD4+CD25+Foxp3+ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV
inferredcites →https://doi.org/10.1182/blood-2006-11-060087openalex-snapshot
Interaction between B7-H1 and PD-1 determines initiation and reversal of T-cell anergy
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Immune checkpoint inhibitors in advanced non–small cell lung cancer
inferred← citeshttps://doi.org/10.1002/eji.201041235openalex-snapshot
Combination of lentivector immunization and low‐dose chemotherapy or PD‐1/PD‐L1 blocking primes self‐reactive T cells and induces anti‐tumor immunity
inferred← citeshttps://doi.org/10.1002/eji.201141544openalex-snapshot
PD‐L1 blockade overrides Salmonella typhimurium‐mediated diabetes prevention in NOD mice: No role for Tregs
inferred← citeshttps://doi.org/10.1002/eji.201142275openalex-snapshot
Antigen amount dictates CD 8 + T ‐cell exhaustion during chronic viral infection irrespective of the type of antigen presenting cell
inferred← citeshttps://doi.org/10.1002/eji.201242852openalex-snapshot
T ‐cell exhaustion due to persistent antigen: Quantity not quality?
inferred← citeshttps://doi.org/10.1002/eji.201343701openalex-snapshot
Japanese encephalitis virus expands regulatory T cells by increasing the expression of PD‐L1 on dendritic cells
inferred← citeshttps://doi.org/10.1002/glia.21158openalex-snapshot
The majority of infiltrating CD8 T lymphocytes in multiple sclerosis lesions is insensitive to enhanced PD‐L1 levels on CNS cells
inferred← citeshttps://doi.org/10.1002/hep.25674openalex-snapshot
Chronic inflammation, immune escape, and oncogenesis in the liver: A unique neighborhood for novel intersections
inferred← citeshttps://doi.org/10.1007/978-3-662-43492-5_6openalex-snapshot
IL-10: Achieving Balance During Persistent Viral Infection
inferred← citeshttps://doi.org/10.1007/s00705-014-2298-6openalex-snapshot
Inhibition of the PI3K/Akt pathway by Ly294002 does not prevent establishment of persistent Junín virus infection in Vero cells
inferred← citeshttps://doi.org/10.1007/s11060-025-04978-2openalex-snapshot
Improving IL12 immunotherapy in glioblastoma by targeting the long noncoding RNA INCR1
inferred← citeshttps://doi.org/10.1007/s11481-012-9421-9openalex-snapshot
Neuroimmunology of the Atherosclerotic Plaque: A Morphological Approach
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Divergent Function of Programmed Death-Ligand 1 in Donor Tissue versus Recipient Immune System in a Murine Model of Bronchiolitis Obliterans
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The anthelmintic flubendazole blocks human melanoma growth and metastasis and suppresses programmed cell death protein-1 and myeloid-derived suppressor cell accumulation
inferred← citeshttps://doi.org/10.1016/j.ccell.2014.10.018openalex-snapshot
The Immunoreceptor TIGIT Regulates Antitumor and Antiviral CD8 + T Cell Effector Function
inferred← citeshttps://doi.org/10.1016/j.celrep.2014.01.020openalex-snapshot
Tissue-Expressed B7-H1 Critically Controls Intestinal Inflammation
inferred← citeshttps://doi.org/10.1016/j.celrep.2024.114401openalex-snapshot
IRF4 impedes human CD8 T cell function and promotes cell proliferation and PD-1 expression
inferred← citeshttps://doi.org/10.1016/j.celrep.2026.116939openalex-snapshot
PD-L1 is an intrinsic switch for natural killer cell-mediated, TRAIL-dependent antiviral function
inferred← citeshttps://doi.org/10.1016/j.celrep.2026.117910openalex-snapshot
Combined type 2 cytokine blockade enhances PD-1-mediated antitumor immunity
inferred← citeshttps://doi.org/10.1016/j.chom.2012.03.009openalex-snapshot
Emergence of Distinct Multiarmed Immunoregulatory Antigen-Presenting Cells during Persistent Viral Infection
inferred← citeshttps://doi.org/10.1016/j.chom.2013.05.014openalex-snapshot
Networking at the Level of Host Immunity: Immune Cell Interactions during Persistent Viral Infections
inferred← citeshttps://doi.org/10.1016/j.coi.2013.03.003openalex-snapshot
Manipulating the PD-1 pathway to improve immunity
inferred← citeshttps://doi.org/10.1016/j.immuni.2014.10.013openalex-snapshot
The Transcription Factor FoxO1 Sustains Expression of the Inhibitory Receptor PD-1 and Survival of Antiviral CD8+ T Cells during Chronic Infection
inferred← citeshttps://doi.org/10.1016/j.immuni.2016.05.002openalex-snapshot
Coinhibitory Pathways in the B7-CD28 Ligand-Receptor Family
inferred← citeshttps://doi.org/10.1016/j.immuni.2016.07.017openalex-snapshot
Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4 + T Cell Immunity
inferred← citeshttps://doi.org/10.1016/j.immuni.2018.12.024openalex-snapshot
Liver-Resident NK Cells Control Antiviral Activity of Hepatic T Cells via the PD-1-PD-L1 Axis
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.112419openalex-snapshot
Immune checkpoint inhibitors and SARS-CoV2 infection
inferred← citeshttps://doi.org/10.1016/j.isci.2026.114776openalex-snapshot
TLR7-mediated inflammation drives PD-L1 upregulation and T cell exhaustion during influenza A virus infection
inferred← citeshttps://doi.org/10.1016/j.it.2012.12.002openalex-snapshot
The risks of targeting co-inhibitory pathways to modulate pathogen-directed T cell responses
inferred← citeshttps://doi.org/10.1016/j.it.2015.02.008openalex-snapshot
Overcoming T cell exhaustion in infection and cancer
inferred← citeshttps://doi.org/10.1016/j.jaut.2019.05.013openalex-snapshot
Analysis of the PD-1/PD-L1 axis in human autoimmune thyroid disease: Insights into pathogenesis and clues to immunotherapy associated thyroid autoimmunity
inferred← citeshttps://doi.org/10.1016/j.jhep.2016.02.034openalex-snapshot
Counter-regulation of rejection activity against human liver grafts by donor PD-L1 and recipient PD-1 interaction
inferred← citeshttps://doi.org/10.1016/j.jhep.2022.02.028openalex-snapshot
Transcriptional switch of hepatocytes initiates macrophage recruitment and T-cell suppression in endotoxemia
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2012.10.001openalex-snapshot
Plasmacytoid dendritic cells: Biomarkers or potential therapeutic targets in atherosclerosis?
inferred← citeshttps://doi.org/10.1016/j.stem.2011.07.005openalex-snapshot
Tolerance Induction by Allogeneic Hematopoietic Stem Cells
inferred← citeshttps://doi.org/10.1016/j.trecan.2023.11.008openalex-snapshot
Harnessing CD8 T cell responses using PD-1–IL-2 combination therapy
inferred← citeshttps://doi.org/10.1016/j.vaccine.2014.12.082openalex-snapshot
Beyond adjuvants: Immunomodulation strategies to enhance T cell immunity
inferred← citeshttps://doi.org/10.1016/j.ymthe.2020.12.034openalex-snapshot
Cancer-secreted exosomal miR-1468-5p promotes tumor immune escape via the immunosuppressive reprogramming of lymphatic vessels
inferred← citeshttps://doi.org/10.1038/cmi.2014.49openalex-snapshot
Type 1 interferon-induced IL-7 maintains CD8+ T-cell responses and homeostasis by suppressing PD-1 expression in viral hepatitis
inferred← citeshttps://doi.org/10.1038/mtna.2012.63openalex-snapshot
Lipidoid Nanoparticles Containing PD-L1 siRNA Delivered In Vivo Enter Kupffer Cells and Enhance NK and CD8+ T Cell-mediated Hepatic Antiviral Immunity
inferred← citeshttps://doi.org/10.1038/ncomms14572openalex-snapshot
Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice
inferred← citeshttps://doi.org/10.1038/nri.2017.108openalex-snapshot
The diverse functions of the PD1 inhibitory pathway
inferred← citeshttps://doi.org/10.1038/nri3740openalex-snapshot
T cell differentiation in chronic infection and cancer: functional adaptation or exhaustion?
inferred← citeshttps://doi.org/10.1038/nri3790openalex-snapshot
Clinical blockade of PD1 and LAG3 — potential mechanisms of action
inferred← citeshttps://doi.org/10.1038/nri3846openalex-snapshot
Lymph node fibroblastic reticular cells in health and disease
inferred← citeshttps://doi.org/10.1038/s12276-024-01301-3openalex-snapshot
Harnessing IL-2 for immunotherapy against cancer and chronic infection: a historical perspective and emerging trends
inferred← citeshttps://doi.org/10.1038/s41467-020-15025-1openalex-snapshot
TIGIT limits immune pathology during viral infections
inferred← citeshttps://doi.org/10.1038/s41568-021-00431-4openalex-snapshot
Programmed death ligand 1 signals in cancer cells
inferred← citeshttps://doi.org/10.1038/s41568-024-00681-yopenalex-snapshot
Lymphatic vessels in the age of cancer immunotherapy
inferred← citeshttps://doi.org/10.1038/s41577-023-00857-xopenalex-snapshot
Splenic stromal niches in homeostasis and immunity
inferred← citeshttps://doi.org/10.1038/s41577-026-01328-9openalex-snapshot
New insights into progenitor exhausted T cell populations
inferred← citeshttps://doi.org/10.1038/s41577-026-01357-4openalex-snapshot
The effects of IFNγ on tissue physiology through structural cells
inferred← citeshttps://doi.org/10.1038/s41586-022-05257-0openalex-snapshot
PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program
inferred← citeshttps://doi.org/10.1038/s41586-026-10266-4openalex-snapshot
Exposed phosphatidylserine is an inhibitory molecule in T cell exhaustion
inferred← citeshttps://doi.org/10.1038/s41598-018-26471-9openalex-snapshot
Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes
inferred← citeshttps://doi.org/10.1038/s41598-018-28901-0openalex-snapshot
Autoantigen-Harboring Apoptotic Cells Hijack the Coinhibitory Pathway of T Cell Activation
inferred← citeshttps://doi.org/10.1073/pnas.1201131109openalex-snapshot
Regulatory T cells use programmed death 1 ligands to directly suppress autoreactive B cells in vivo
inferred← citeshttps://doi.org/10.1073/pnas.1205850109openalex-snapshot
Immortalized clones of fibroblastic reticular cells activate virus-specific T cells during virus infection
inferred← citeshttps://doi.org/10.1073/pnas.1718217115openalex-snapshot
Role of PD-1 during effector CD8 T cell differentiation
inferred← citeshttps://doi.org/10.1080/20002297.2021.1978732openalex-snapshot
Campylobacter concisus upregulates PD-L1 mRNA expression in IFN-γ sensitized intestinal epithelial cells and induces cell death in esophageal epithelial cells
inferred← citeshttps://doi.org/10.1080/2162402x.2020.1736792openalex-snapshot
LAG-3 and PD-1+LAG-3 inhibition promote anti-tumor immune responses in human autologous melanoma/T cell co-cultures
inferred← citeshttps://doi.org/10.1084/jem.20121015openalex-snapshot
Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice
inferred← citeshttps://doi.org/10.1084/jem.20121416openalex-snapshot
PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis
inferred← citeshttps://doi.org/10.1084/jem.20132577openalex-snapshot
Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection
inferred← citeshttps://doi.org/10.1084/jem.20180654openalex-snapshot
IFNγ-activated dermal lymphatic vessels inhibit cytotoxic T cells in melanoma and inflamed skin
inferred← citeshttps://doi.org/10.1084/jem.20192291openalex-snapshot
Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses
inferred← citeshttps://doi.org/10.1084/jem.20241217openalex-snapshot
Inhibitory receptor agonists: Emerging strategies in immune modulation
inferred← citeshttps://doi.org/10.1089/aid.2015.0258openalex-snapshot
Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID “Meet the Experts” 2015 Workshop Summary
inferred← citeshttps://doi.org/10.1093/infdis/jis304openalex-snapshot
PD-1–Mediated Attrition of Polyfunctional Memory CD8+ T Cells in Chronic Toxoplasma Infection
inferred← citeshttps://doi.org/10.1093/infdis/jiu472openalex-snapshot
Triggering Through Toll-like Receptor 2 Limits Chronically Stimulated T-helper Type 1 Cells From Undergoing Exhaustion
inferred← citeshttps://doi.org/10.1097/aln.0b013e31823422e8openalex-snapshot
Advances in the Management of Sepsis and the Understanding of Key Immunologic Defects
inferred← citeshttps://doi.org/10.1101/2025.09.26.678820openalex-snapshot
Therapeutic Blockade of Type 2 Cytokines and PD1 Unleashes Anti-Tumor Immunity Through Coordinated Reprogramming of Innate and Adaptive Immune Surveillance
inferred← citeshttps://doi.org/10.1101/sqb.2013.78.019869openalex-snapshot
Programmed Cell Death 1-Directed Immunotherapy for Enhancing T-Cell Function
inferred← citeshttps://doi.org/10.1101/sqb.78.019869openalex-snapshot
Programmed Cell Death 1-Directed Immunotherapy for Enhancing T-Cell Function
inferred← citeshttps://doi.org/10.1111/febs.16084openalex-snapshot
Contributions of PD‐L1 reverse signaling to dendritic cell trafficking
inferred← citeshttps://doi.org/10.1111/j.1365-2184.2012.00813.xopenalex-snapshot
Ex vivo expansion of cord blood progenitors impairs their short‐term and long‐term repopulating activity associated with transcriptional dysregulation of signalling networks
inferred← citeshttps://doi.org/10.1111/j.1365-2893.2010.01421.xopenalex-snapshot
Potential role of soluble B7‐H3 in liver immunopathogenesis during chronic HBV infection
inferred← citeshttps://doi.org/10.1126/sciadv.aea8737openalex-snapshot
Selective elimination of circulating effector CD8 T cells via LTβR blockade separates anti-CD137 efficacy from toxicity
inferred← citeshttps://doi.org/10.1126/science.aaf0683openalex-snapshot
Rescue of exhausted CD8 T cells by PD-1–targeted therapies is CD28-dependent
inferred← citeshttps://doi.org/10.1126/sciimmunol.abg3551openalex-snapshot
Tumor-draining lymph nodes: At the crossroads of metastasis and immunity
inferred← citeshttps://doi.org/10.1126/scitranslmed.3003130openalex-snapshot
The PDL1-PD1 Axis Converts Human T H 1 Cells into Regulatory T Cells
inferred← citeshttps://doi.org/10.1128/jvi.00797-24openalex-snapshot
Genetic absence of PD-L1 does not restore CD8 + T cell function during respiratory virus infection and delays virus clearance
inferred← citeshttps://doi.org/10.1128/jvi.01233-12openalex-snapshot
Seoul Virus-Infected Rat Lung Endothelial Cells and Alveolar Macrophages Differ in Their Ability To Support Virus Replication and Induce Regulatory T Cell Phenotypes
inferred← citeshttps://doi.org/10.1128/jvi.02290-10openalex-snapshot
The Role of LAT in Increased CD8 + T Cell Exhaustion in Trigeminal Ganglia of Mice Latently Infected with Herpes Simplex Virus 1
inferred← citeshttps://doi.org/10.1128/jvi.05548-11openalex-snapshot
Longitudinal Analysis of the Human T Cell Response during Acute Hantavirus Infection
inferred← citeshttps://doi.org/10.1146/annurev-med-012017-043208openalex-snapshot
CD8 T Cell Exhaustion in Chronic Infection and Cancer: Opportunities for Interventions
inferred← citeshttps://doi.org/10.1155/2013/361501openalex-snapshot
PD-L1 Blockade Attenuated Sepsis-Induced Liver Injury in a Mouse Cecal Ligation and Puncture Model
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-12-2063openalex-snapshot
Antagonist Antibodies to PD-1 and B7-H1 (PD-L1) in the Treatment of Advanced Human Cancer
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-13-2234openalex-snapshot
Antagonist Antibodies to PD-1 and B7-H1 (PD-L1) in the Treatment of Advanced Human Cancer—Response
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-22-3468openalex-snapshot
The Interplay between Metabolic Adaptations and Diet in Cancer Immunotherapy
inferred← citeshttps://doi.org/10.1158/2326-6066.c.6548200.v1openalex-snapshot
Data from Antigen-Specific Bacterial Vaccine Combined with Anti-PD-L1 Rescues Dysfunctional Endogenous T Cells to Reject Long-Established Cancer
inferred← citeshttps://doi.org/10.1158/2326-6066.c.6548542.v1openalex-snapshot
Data from Response to BRAF Inhibition in Melanoma Is Enhanced When Combined with Immune Checkpoint Blockade
inferred← citeshttps://doi.org/10.1158/2326-6066.cir-13-0058openalex-snapshot
Antigen-Specific Bacterial Vaccine Combined with Anti-PD-L1 Rescues Dysfunctional Endogenous T Cells to Reject Long-Established Cancer
inferred← citeshttps://doi.org/10.1158/2326-6066.cir-13-0215openalex-snapshot
Response to BRAF Inhibition in Melanoma Is Enhanced When Combined with Immune Checkpoint Blockade
inferred← citeshttps://doi.org/10.1161/atvbaha.111.224162openalex-snapshot
CD155 on Human Vascular Endothelial Cells Attenuates the Acquisition of Effector Functions in CD8 T Cells
inferred← citeshttps://doi.org/10.1161/circresaha.111.256529openalex-snapshot
Plasmacytoid Dendritic Cells Protect Against Atherosclerosis by Tuning T-Cell Proliferation and Activity
inferred← citeshttps://doi.org/10.1172/jci.insight.97011openalex-snapshot
Peripheral tissues reprogram CD8+ T cells for pathogenicity during graft-versus-host disease
inferred← citeshttps://doi.org/10.1172/jci159925openalex-snapshot
Immune tolerance against infused FVIII in hemophilia A is mediated by PD-L1+ Tregs
inferred← citeshttps://doi.org/10.1172/jci41446openalex-snapshot
Nonhematopoietic antigen blocks memory programming of alloreactive CD8+ T cells and drives their eventual exhaustion in mouse models of bone marrow transplantation
inferred← citeshttps://doi.org/10.1172/jci62860openalex-snapshot
Viral acute lower respiratory infections impair CD8+ T cells through PD-1
inferred← citeshttps://doi.org/10.1172/jci67008openalex-snapshot
PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells
inferred← citeshttps://doi.org/10.1172/jci91138openalex-snapshot
PD-L1 interacts with CD80 to regulate graft-versus-leukemia activity of donor CD8+ T cells
inferred← citeshttps://doi.org/10.1172/jci94196openalex-snapshot
PD-L1 serves as a double agent in separating GVL from GVHD
inferred← citeshttps://doi.org/10.1186/s40425-018-0353-7openalex-snapshot
Influenza vaccination of cancer patients during PD-1 blockade induces serological protection but may raise the risk for immune-related adverse events
inferred← citeshttps://doi.org/10.12688/f1000research.143472.1openalex-snapshot
Distinct fibroblast functions associated with fibrotic and immune-mediated inflammatory diseases and their implications for therapeutic development
inferred← citeshttps://doi.org/10.1371/journal.pbio.3000072openalex-snapshot
Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts
inferred← citeshttps://doi.org/10.1371/journal.pone.0026196openalex-snapshot
The Expression of PD-1 Ligands and Their Involvement in Regulation of T Cell Functions in Acute and Chronic Woodchuck Hepatitis Virus Infection
inferred← citeshttps://doi.org/10.1371/journal.pone.0039757openalex-snapshot
Blocking of PDL-1 Interaction Enhances Primary and Secondary CD8 T Cell Response to Herpes Simplex Virus-1 Infection
inferred← citeshttps://doi.org/10.1371/journal.pone.0184254openalex-snapshot
PD-1 and CTLA-4 up regulation on donor T cells is insufficient to prevent GvHD in allo-HSCT recipients
inferred← citeshttps://doi.org/10.1371/journal.ppat.1002913openalex-snapshot
OX40 Facilitates Control of a Persistent Virus Infection
inferred← citeshttps://doi.org/10.1371/journal.ppat.1004675openalex-snapshot
Enhanced CD8 T Cell Responses through GITR-Mediated Costimulation Resolve Chronic Viral Infection
inferred← citeshttps://doi.org/10.1371/journal.ppat.1010673openalex-snapshot
Active PD-L1 incorporation within HIV virions functionally impairs T follicular helper cells
inferred← citeshttps://doi.org/10.14776/kjpid.2013.20.3.123openalex-snapshot
Measles Viral Infection in PD-1 Gene Knockout Mice
inferred← citeshttps://doi.org/10.1517/14712598.2015.1049596openalex-snapshot
Nivolumab in renal cell carcinoma
inferred← citeshttps://doi.org/10.1615/forumimmundisther.2015014188openalex-snapshot
Reinvigorating Exhausted T Cells by Blockade of the PD-1 Pathway
inferred← citeshttps://doi.org/10.18130/v3s806openalex-snapshot
Regulation of the Intrahepatic CD8+ T Lymphocyte
inferred← citeshttps://doi.org/10.2147/dddt.s148443openalex-snapshot
The coexpression of multi-immune inhibitory receptors on T lymphocytes in primary non-small-cell lung cancer
inferred← citeshttps://doi.org/10.26481/dis.20120413idopenalex-snapshot
Peri- and extravascular inflammation : impact on atherosclerosis
inferred← citeshttps://doi.org/10.3109/08820139.2013.782317openalex-snapshot
PD-1 Regulates T Cell Proliferation in a Tissue and Subset-Specific Manner During Normal Mouse Pregnancy
inferred← citeshttps://doi.org/10.31857/s0301179824030045openalex-snapshot
Lung cancer and pulmonary tuberculosis: key features of molecular mechanisms of concomitant disease
inferred← citeshttps://doi.org/10.32469/10355/88918openalex-snapshot
Virus interactions with the sphingolipid network : sphingosine kinase 2 in immunosuppression, immunopathology, and viral propagation
inferred← citeshttps://doi.org/10.3389/fcimb.2019.00207openalex-snapshot
The PD-1/PD-L1 Axis and Virus Infections: A Delicate Balance
inferred← citeshttps://doi.org/10.3389/fcimb.2020.00430openalex-snapshot
Differential CD4 T Regulatory Cell Phenotype Induced by Andes Hantavirus Glycoprotein
inferred← citeshttps://doi.org/10.3389/fcvm.2021.619690openalex-snapshot
Endothelial Cells in Emerging Viral Infections
inferred← citeshttps://doi.org/10.3389/fimmu.2015.00603openalex-snapshot
T Lymphocyte–Endothelial Interactions: Emerging Understanding of Trafficking and Antigen-Specific Immunity
inferred← citeshttps://doi.org/10.3389/fimmu.2018.01614openalex-snapshot
Glyco-Engineered Anti-Human Programmed Death-Ligand 1 Antibody Mediates Stronger CD8 T Cell Activation Than Its Normal Glycosylated and Non-Glycosylated Counterparts
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1029438openalex-snapshot
Role of regulation of PD-1 and PD-L1 expression in sepsis
inferred← citeshttps://doi.org/10.3389/fimmu.2024.1449291openalex-snapshot
Lymphatic system regulation of anti-cancer immunity and metastasis
inferred← citeshttps://doi.org/10.3389/fimmu.2026.1756987openalex-snapshot
Advances in IL–2–based cancer immunotherapy and the synergistic role of stem–like CD8+ T cells in IL–2 and PD–1 combination therapy
inferred← citeshttps://doi.org/10.3389/fmicb.2014.00733openalex-snapshot
Endothelial cell dysfunction in viral hemorrhage and edema
inferred← citeshttps://doi.org/10.3390/cancers12113285openalex-snapshot
The Immune Checkpoint PD-1 in Natural Killer Cells: Expression, Function and Targeting in Tumour Immunotherapy
inferred← citeshttps://doi.org/10.3390/cancers16233918openalex-snapshot
Advances in Immunotherapy for Endometrial Cancer: Insights into MMR Status and Tumor Microenvironment
inferred← citeshttps://doi.org/10.3390/cells9092043openalex-snapshot
Cellular Uptake of siRNA-Loaded Nanocarriers to Knockdown PD-L1: Strategies to Improve T-cell Functions
inferred← citeshttps://doi.org/10.3390/ijms25179659openalex-snapshot
Predictive Biomarkers and Resistance Mechanisms of Checkpoint Inhibitors in Malignant Solid Tumors
inferred← citeshttps://doi.org/10.3390/ijms26178533openalex-snapshot
Machine Learning Integration of Bulk and Single-Cell RNA-Seq Data Reveals Cathepsin B as a Central PANoptosis Regulator in Influenza
inferred← citeshttps://doi.org/10.3390/ph19081212openalex-snapshot
Targeting Immune Checkpoint Proteins in Cancer Therapy and the Potential of RNAi-Based Immunotherapy
inferred← citeshttps://doi.org/10.3390/v11100885openalex-snapshot
Viral Infections and Autoimmune Disease: Roles of LCMV in Delineating Mechanisms of Immune Tolerance
inferred← citeshttps://doi.org/10.4049/jimmunol.1003304openalex-snapshot
CD4 T Cells Promote Rather than Control Tuberculosis in the Absence of PD-1–Mediated Inhibition
inferred← citeshttps://doi.org/10.4049/jimmunol.1400497openalex-snapshot
Both PD-1 Ligands Protect the Kidney from Ischemia Reperfusion Injury
inferred← citeshttps://doi.org/10.4049/jimmunol.1400954openalex-snapshot
Programmed Death-1 Pathway in Host Tissues Ameliorates Th17/Th1-Mediated Experimental Chronic Graft-versus-Host Disease
inferred← citeshttps://doi.org/10.4049/jimmunol.1402180openalex-snapshot
Programmed Death-1 Controls T Cell Survival by Regulating Oxidative Metabolism
inferred← citeshttps://doi.org/10.4049/jimmunol.1701617openalex-snapshot
PD-L1–Independent Mechanisms Control the Resistance of Melanoma to CD4+ T Cell Adoptive Immunotherapy
inferred← citeshttps://doi.org/10.4049/jimmunol.2300396openalex-snapshot
Neonatal CD8+ T Cells Resist Exhaustion during Chronic Infection
inferred← citeshttps://doi.org/10.4103/ijmm.ijmm_18_439openalex-snapshot
Frequencies of Regulatory Subsets of CD4+ TH Cells in Peripheral Blood in Mycobacterium Tuberculosis-Infected Individuals and Healthy Contacts in a High-Burden Setting from Assam, Northeast India
inferred← citeshttps://doi.org/10.4110/in.2020.20.e2openalex-snapshot
Re-defining T-Cell Exhaustion: Subset, Function, and Regulation
inferred← citeshttps://doi.org/10.4314/tjpr.v10i2.66562openalex-snapshot
Immunomodulatory Effect of the Aqueous Extract of Erigeron floribundus (Kunth) Sch Beep (Asteraceae) Leaf in Rabbits
inferred← citeshttps://doi.org/10.5114/ceji/205377openalex-snapshot
Soluble PD-L2 and LAG-3 serum concentrations may be associated with COVID-19 activity and recovery
inferred← citeshttps://doi.org/10.5858/arpa.2016-0361-raopenalex-snapshot
Programmed Death Ligand-1 (PD-L1) Expression in the Programmed Death Receptor-1 (PD-1)/PD-L1 Blockade: A Key Player Against Various Cancers
inferred← citeshttps://doi.org/10.64898/2026.08.03.742579openalex-snapshot
Humanized Anti-PD-1 Antibodies Generated Using The Conditional Kernel-Elastic Autoencoder
inferred← citeshttps://doi.org/10.70675/8a93b17bz416az4e49z9a3bz92c1c8a4cf8copenalex-snapshot
Translating IL-2/anti-IL-2 antibody complexes treatment for human tumor immunotherapy
inferred← citeshttps://doi.org/10.70675/bd87267ez6461z4759z8173z6f34bba4e52fopenalex-snapshot
Facteurs génétiques et post-génétiques associés au développement de la sclérose en plaques
inferred← citeshttps://doi.org/10.7518/hxkq.2015.04.009openalex-snapshot
[Programmed death ligand 1 negatively regulates inflammatory response of chronic periodontitis].
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