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Deriving chemosensitivity from cell lines: Forensic bioinformatics and reproducible research in high-throughput biology

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4 of the 28 references listed on this page are in the Retraction Watch database as retracted (export 2026-10-28): 10.1016/s1470-2045(07)70345-5 (notice 2011-02-01), 10.1038/nm1491 (notice 2011-01-07), 10.1200/jco.2007.11.0593 (notice 2010-12-10), 10.1371/journal.pone.0001908 (notice 2011-09-02).

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ijc.21570openalex-snapshot
Gene expression profiling of 30 cancer cell lines predicts resistance towards 11 anticancer drugs at clinically achieved concentrations
inferredcites →https://doi.org/10.1007/0-306-48354-8_5openalex-snapshot
Organ-Specific Differences in Gene Expression and Unigene Annotations Describing Source Material
inferredcites →https://doi.org/10.1007/978-3-642-57489-4_89openalex-snapshot
Sweave: Dynamic Generation of Statistical Reports Using Literate Data Analysis
inferredcites →https://doi.org/10.1007/bf01833154openalex-snapshot
A conjecture of Gy. Petruska
inferredcites →https://doi.org/10.1016/j.ccr.2005.03.002openalex-snapshot
Identification of genes associated with chemotherapy crossresistance and treatment response in childhood acute lymphoblastic leukemia
inferredcites →https://doi.org/10.1016/s0140-6736(03)14023-8openalex-snapshot
Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer
inferredcites →https://doi.org/10.1016/s1470-2045(07)70345-5openalex-snapshot
RETRACTED: Validation of gene signatures that predict the response of breast cancer to neoadjuvant chemotherapy: a substudy of the EORTC 10994/BIG 00-01 clinical trial
inferredcites →https://doi.org/10.1038/ng.295openalex-snapshot
Repeatability of published microarray gene expression analyses
inferredcites →https://doi.org/10.1038/nm0808-889openalex-snapshot
Erratum: Corrigendum: Genomic signatures to guide the use of chemotherapeutics
inferredcites →https://doi.org/10.1038/nm1107-1276bopenalex-snapshot
Microarrays: retracing steps
inferredcites →https://doi.org/10.1038/nm1107-1277openalex-snapshot
Reply to 'Microarrays: retracing steps'
inferredcites →https://doi.org/10.1038/nm1491openalex-snapshot
Genomic signatures to guide the use of chemotherapeutics
inferredcites →https://doi.org/10.1056/nejmoa033513openalex-snapshot
Gene-Expression Patterns in Drug-Resistant Acute Lymphoblastic Leukemia Cells and Response to Treatment
inferredcites →https://doi.org/10.1093/bioinformatics/btg484openalex-snapshot
Reproducibility of SELDI-TOF protein patterns in serum: comparing datasets from different experiments
inferredcites →https://doi.org/10.1093/jnci/dji008openalex-snapshot
Signal in Noise: Evaluating Reported Reproducibility of Serum Proteomic Tests for Ovarian Cancer
inferredcites →https://doi.org/10.1093/jnci/dji237openalex-snapshot
Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK)
inferredcites →https://doi.org/10.1158/1078-0432.ccr-08-1916openalex-snapshot
Genomic and Molecular Profiling Predicts Response to Temozolomide in Melanoma
inferredcites →https://doi.org/10.1158/1535-7163.mct-08-0642openalex-snapshot
A genomic approach to identify molecular pathways associated with chemotherapy resistance
inferredcites →https://doi.org/10.1186/1471-2105-9-231openalex-snapshot
Automating dChip: toward reproducible sharing of microarray data analysis
inferredcites →https://doi.org/10.1198/106186007x178663openalex-snapshot
Statistical Analyses and Reproducible Research
inferredcites →https://doi.org/10.1200/jco.2007.11.0593openalex-snapshot
Pharmacogenomic Strategies Provide a Rational Approach to the Treatment of Cisplatin-Resistant Patients With Advanced Cancer
inferredcites →https://doi.org/10.1200/jco.2007.15.1951openalex-snapshot
Run Batch Effects Potentially Compromise the Usefulness of Genomic Signatures for Ovarian Cancer
inferredcites →https://doi.org/10.1214/09-aoas291openalex-snapshot
Deriving chemosensitivity from cell lines: Forensic bioinformatics and reproducible research in high-throughput biology
inferredcites →https://doi.org/10.1371/journal.pone.0001908openalex-snapshot
An Integrated Approach to the Prediction of Chemotherapeutic Response in Patients with Breast Cancer
inferredcites →https://doi.org/10.1677/erc.0.0110163openalex-snapshot
High-resolution serum proteomic features for ovarian cancer detection.
inferredcites →https://doi.org/10.1677/erc.1.00868openalex-snapshot
High-resolution serum proteomic patterns for ovarian cancer detection
inferredcites →https://doi.org/10.2202/1544-6115.1034openalex-snapshot
Reproducible Research: A Bioinformatics Case Study
inferredcites →https://doi.org/10.2202/1544-6115.1078openalex-snapshot
A Compendium to Ensure Computational Reproducibility in High-Dimensional Classification Tasks

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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The Digitalization of Science Computational Science as a Field of Inquiry in Design Science Research
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Feasibility, Process, and Outcomes of Cardiovascular Clinical Trial Data Sharing
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Haploid genetic screens identify genetic vulnerabilities to microtubule‐targeting agents
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Toward the Geoscience Paper of the Future: Best practices for documenting and sharing research from data to software to provenance
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Bibliography
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Clinical Trial Misconduct
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Novel Clinical Trial Designs for Metastatic Lung Cancer
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Challenges and Opportunities for Statistics in Omics Data Analysis
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Advantages and Limits in the Adoption of Reproducible Research and R-Tools for the Analysis of Omic Data
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Fraud in Clinical Trials
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Fraud in Clinical Trials
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Toward Replicability-Aware Modeling and Simulation: Changing the Conduct of M&S in the Information Age
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Reproducibility in Biomedical Research
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Statistical Use and Misuse in Scientific Publications
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Molecular-Based Testing in Breast Disease for Therapeutic Decisions
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Biostatistics and Bioinformatics in Clinical Trials
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Cancer Chemotherapy
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Organoid-AI platforms need integrated governance in drug discovery
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Digitalization of the natural sciences: Design science research and computational science
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A taxonomy for reproducible and replicable research in environmental modelling
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Human B-cell cancer cell lines as a preclinical model for studies of drug effect in diffuse large B-cell lymphoma and multiple myeloma
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Expectations, validity, and reality in gene expression profiling
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Assessing and Comparing the Performance of Molecular Diagnostic Tests
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Regulating Laboratory-Developed Tests
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Reproducible manuscript preparation with RMarkdown application to JMSACL and other Elsevier Journals
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Reproducibility and replicability of rodent phenotyping in preclinical studies
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A practical guide to big data
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Gene expression profiling in breast cancer: classification, prognostication, and prediction
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Statistical Inference as Severe Testing
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Preface
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Beyond Probabilism and Performance
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Error Probing Tools versus Logics of Evidence
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Induction and Confirmation
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Falsification, Pseudoscience, Induction
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Ingenious and Severe Tests
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It’s The Methods, Stupid
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Capability and Severity: Deeper Concepts
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The Myth of “The Myth of Objectivity”
inferred← citeshttps://doi.org/10.1017/9781107286184.010openalex-snapshot
Rejection Fallacies: Who’s Exaggerating What?
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Auditing: Biasing Selection Effects and Randomization
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More Auditing: Objectivity and Model Checking
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Power: Pre-data and Post-data
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How Not to Corrupt Power
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Deconstructing the N-P versus Fisher Debates
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What Ever Happened to Bayesian Foundations?
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Pragmatic and Error Statistical Bayesians
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Souvenirs
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Index
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Can We Be Wrong? The Problem of Textual Evidence in a Time of Data
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Cancer trial errors revealed
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Troubled geneticist rebuffed by US patent office
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Taming the dragon: genomic biomarkers to individualize the treatment of cancer
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Data handling errors spur debate over clinical trial
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Challenges translating breast cancer gene signatures into the clinic
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Cloud computing for genomic data analysis and collaboration
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Reuse of public genome-wide gene expression data
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Gray matter correlates of childhood maltreatment lack replicability in a multi-cohort brain-wide association study
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A visual tool for defining reproducibility and replicability
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Quantify and control reproducibility in high-throughput experiments
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Open Science Practices in Communication Sciences and Disorders: A Survey
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“1-800-Help-Me-With-Open-Science-Stuff”: A Qualitative Examination of Open Science Practices in Communication Sciences and Disorders
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Trends and Developments in Bioinformatics in 2010: Prospects and Perspectives
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Reproducible research can still be wrong: Adopting a prevention approach
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Challenges and Opportunities for Statistics in the Next 25 Years
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Integrating Ethics into the Guidelines for Assessment and Instruction in Statistics Education (GAISE)
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Quality assurance for multiplexed assays – how can it be achieved?
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Fabrication in a study about honesty: A lost episode of columbo illustrating how forensic statistics is performed
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Reproducibility in M&S research: issues, strategies and implications for model development environments
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Establishing a framework for Open Geographic Information science
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Practical methods for incorporating open science into your speech-language-hearing science research workflow across study designs
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Special issue introduction: Statistical Methods in Precision Medicine: Diagnostic, Prognostic, Predictive and Therapeutic
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Opinionated Practices for Teaching Reproducibility: Motivation, Guided Instruction and Practice
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Statistical proof? The problem of irreproducibility
inferred← citeshttps://doi.org/10.1093/ajcp/aqy149openalex-snapshot
Widespread Incorrect Implementation of the Hoffmann Method, the Correct Approach, and Modern Alternatives
inferred← citeshttps://doi.org/10.1093/aje/kwx066openalex-snapshot
A Pragmatic Approach for Reproducible Research With Sensitive Data
inferred← citeshttps://doi.org/10.1093/bib/bbaa265openalex-snapshot
Drug–drug similarity measure and its applications
inferred← citeshttps://doi.org/10.1093/bib/bbad375openalex-snapshot
The five pillars of computational reproducibility: bioinformatics and beyond
inferred← citeshttps://doi.org/10.1093/bib/bbq084openalex-snapshot
Case studies in reproducibility
inferred← citeshttps://doi.org/10.1093/bib/bbr008openalex-snapshot
Caveats and pitfalls of ROC analysis in clinical microarray research (and how to avoid them)
inferred← citeshttps://doi.org/10.1093/bib/bbt011openalex-snapshot
Reproducible probe-level analysis of the Affymetrix Exon 1.0 ST array with R/Bioconductor
inferred← citeshttps://doi.org/10.1093/bioinformatics/btr529openalex-snapshot
inSilicoDb: an R/Bioconductor package for accessing human Affymetrix expert-curated datasets from GEO
inferred← citeshttps://doi.org/10.1093/biostatistics/kxt007openalex-snapshot
An estimate of the science-wise false discovery rate and application to the top medical literature
inferred← citeshttps://doi.org/10.1093/biostatistics/kxt034openalex-snapshot
Discussion: Difficulties in making inferences about scientific truth from distributions of published p-values
inferred← citeshttps://doi.org/10.1093/biostatistics/kxt038openalex-snapshot
Rejoinder: An estimate of the science-wise false discovery rate and application to the top medical literature
inferred← citeshttps://doi.org/10.1093/clinchem/hvab165openalex-snapshot
Artificial Intelligence and Mapping a New Direction in Laboratory Medicine: A Review
inferred← citeshttps://doi.org/10.1093/ije/dyu149openalex-snapshot
Good practices for quantitative bias analysis
inferred← citeshttps://doi.org/10.1093/jalm/jfac088openalex-snapshot
The Case for Including Data and Code with ML Publications in Laboratory Medicine
inferred← citeshttps://doi.org/10.1093/jalm/jfac107openalex-snapshot
Should We Teach Data Science to Laboratorians-in-Training?
inferred← citeshttps://doi.org/10.1093/jamiaopen/ooaa043openalex-snapshot
Facilitating reproducible research through direct connection of data analysis with manuscript preparation: StatTag for connecting statistical software to Microsoft Word
inferred← citeshttps://doi.org/10.1093/jnci/djt202openalex-snapshot
Independent Validation of a Model Using Cell Line Chemosensitivity to Predict Response to Therapy
inferred← citeshttps://doi.org/10.1093/jnci/dju048openalex-snapshot
Risk Prediction for Late-Stage Ovarian Cancer by Meta-analysis of 1525 Patient Samples
inferred← citeshttps://doi.org/10.1093/jnci/dju049openalex-snapshot
Comparative Meta-analysis of Prognostic Gene Signatures for Late-Stage Ovarian Cancer
inferred← citeshttps://doi.org/10.1093/nar/gkr533openalex-snapshot
A global insight into a cancer transcriptional space using pancreatic data: importance, findings and flaws
inferred← citeshttps://doi.org/10.1097/tp.0000000000001622openalex-snapshot
Biomarker Guidelines for High-Dimensional Genomic Studies in Transplantation: Adding Method to the Madness
inferred← citeshttps://doi.org/10.1098/rsif.2011.0616openalex-snapshot
A formal mathematical framework for physiological observations, experiments and analyses
inferred← citeshttps://doi.org/10.1098/rsif.2013.1030openalex-snapshot
Relevance relations for the concept of reproducibility
inferred← citeshttps://doi.org/10.1098/rsos.240313openalex-snapshot
Measuring transparency in the social sciences: political science and international relations
inferred← citeshttps://doi.org/10.1101/018168openalex-snapshot
Measuring the Contribution of Genomic Predictors to Improving Estimator Precision in Randomized trials
inferred← citeshttps://doi.org/10.1101/066803openalex-snapshot
A statistical definition for reproducibility and replicability
inferred← citeshttps://doi.org/10.1101/079350openalex-snapshot
Reproducibility and replicability of rodent phenotyping in preclinical studies
inferred← citeshttps://doi.org/10.1101/500660openalex-snapshot
Analysis of >30,000 abstracts suggests higher false discovery rates for oncology journals, especially those with low impact factors
inferred← citeshttps://doi.org/10.1108/07419051111184034openalex-snapshot
The AAAS 2011 Annual: Science Without Borders
inferred← citeshttps://doi.org/10.1109/access.2022.3158675openalex-snapshot
Reproducibility in Computing Research: An Empirical Study
inferred← citeshttps://doi.org/10.1109/bibm.2017.8217887openalex-snapshot
Digital reproducibility requirements of computational genomic workflows
inferred← citeshttps://doi.org/10.1109/ethics.2016.7560050openalex-snapshot
A principled approach to reproducible research: a comparative review towards scientific integrity in computational research
inferred← citeshttps://doi.org/10.1109/mcse.2010.113openalex-snapshot
Reproducible Research
inferred← citeshttps://doi.org/10.1109/sai.2017.8252133openalex-snapshot
Cancer survivability with logistic regression
inferred← citeshttps://doi.org/10.1109/wsc.2016.7822185openalex-snapshot
Panel — Reproducible research in discrete event simulation — A must or rather a maybe?
inferred← citeshttps://doi.org/10.1111/gwat.12269openalex-snapshot
Python Scripting: The Return to Programming
inferred← citeshttps://doi.org/10.1111/j.1740-9713.2011.00505.xopenalex-snapshot
The Duke University scandal - what can be done?
inferred← citeshttps://doi.org/10.1111/j.1740-9713.2015.00827.xopenalex-snapshot
The Reproducibility Crisis in Science: A Statistical Counterattack
inferred← citeshttps://doi.org/10.1111/rssa.12132openalex-snapshot
Statistics: a Data Science for the 21st Century
inferred← citeshttps://doi.org/10.1111/rssa.12302openalex-snapshot
Trust in Numbers
inferred← citeshttps://doi.org/10.1126/sciadv.abn3999openalex-snapshot
Toward a taxonomy of trust for probabilistic machine learning
inferred← citeshttps://doi.org/10.1126/science.1211811openalex-snapshot
Improving Validation Practices in “Omics” Research
inferred← citeshttps://doi.org/10.1126/science.aaa6146openalex-snapshot
What is the question?
inferred← citeshttps://doi.org/10.1136/amiajnl-2012-000972openalex-snapshot
Scientific research in the age of omics: the good, the bad, and the sloppy
inferred← citeshttps://doi.org/10.1142/9789814489072_0025openalex-snapshot
Research Methods for Clinical Trials in Personalized Medicine: A Systematic Review
inferred← citeshttps://doi.org/10.1145/2038642.2038650openalex-snapshot
Repeatability, reproducibility, and rigor in systems research
inferred← citeshttps://doi.org/10.1145/2064227.2064247openalex-snapshot
Principles for robust evaluation infrastructure
inferred← citeshttps://doi.org/10.1145/2110497.2110504openalex-snapshot
A new approach for publishing workflows
inferred← citeshttps://doi.org/10.1145/2442776.2442781openalex-snapshot
R3
inferred← citeshttps://doi.org/10.1145/2833138openalex-snapshot
When data is not enough
inferred← citeshttps://doi.org/10.1145/3025171.3025193openalex-snapshot
Towards Automating Data Narratives
inferred← citeshttps://doi.org/10.1145/3311955openalex-snapshot
A Survey on Collecting, Managing, and Analyzing Provenance from Scripts
inferred← citeshttps://doi.org/10.1146/annurev-publhealth-012420-105110openalex-snapshot
Reproducible Research: A Retrospective
inferred← citeshttps://doi.org/10.1146/annurev-statistics-010814-020127openalex-snapshot
Reproducing Statistical Results
inferred← citeshttps://doi.org/10.1146/annurev-statistics-040220-013917openalex-snapshot
Perspective on Data Science
inferred← citeshttps://doi.org/10.1146/annurev-statistics-060116-054104openalex-snapshot
Is Most Published Research Really False?
inferred← citeshttps://doi.org/10.1158/0008-5472.c.6503906.v1openalex-snapshot
Data from Impact of Intertumoral Heterogeneity on Predicting Chemotherapy Response of BRCA1-Deficient Mammary Tumors
inferred← citeshttps://doi.org/10.1158/0008-5472.can-11-4201openalex-snapshot
Impact of Intertumoral Heterogeneity on Predicting Chemotherapy Response of BRCA1-Deficient Mammary Tumors
inferred← citeshttps://doi.org/10.1158/1055-9965.epi-12-1144openalex-snapshot
Knowledge Integration in Cancer: Current Landscape and Future Prospects
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-14-1749openalex-snapshot
Integrating RAS Status into Prognostic Signatures for Adenocarcinomas of the Lung
inferred← citeshttps://doi.org/10.1158/2159-8274.cd-11-0036openalex-snapshot
The BATTLE Trial: A Bold Step toward Improving the Efficiency of Biomarker-Based Drug Development
inferred← citeshttps://doi.org/10.1161/circresaha.114.303819openalex-snapshot
Reproducibility in Science
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Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.