On the public citation graph
Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling
0 signed · 223 inferred · view as graph
Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.
Is this your work? Sign in with ORCID and put your name on the
claims that are yours.
Reference health. See whether every reference in this work resolves to a
known work and none has been retracted — and get a dated CiteStamped
badge you can embed.
What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/(sici)1526-968x(200001)26:1<77::aid-gene10>3.0.co;2-ropenalex-snapshot
The pan-neural bHLH proteins DEADPAN and ASENSE regulate mitotic activity and cdk inhibitor dacapo expression in the Drosophila larval optic lobes
inferredcites →https://doi.org/10.1002/ar.20640openalex-snapshot
Increased Dosage of DYRK1A and Brain Volumetric Alterations in a YAC Model of Partial Trisomy 21
inferredcites →https://doi.org/10.1002/bies.20080openalex-snapshot
Opposing FGF and retinoid pathways: a signalling switch that controls differentiation and patterning onset in the extending vertebrate body axis
inferredcites →https://doi.org/10.1002/hipo.20308openalex-snapshot
Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with down syndrome and in Ts65Dn mice
inferredcites →https://doi.org/10.1002/jmor.1050880104openalex-snapshot
A series of normal stages in the development of the chick embryo
inferredcites →https://doi.org/10.1006/dbio.2002.0675openalex-snapshot
Mnb/Dyrk1A Is Transiently Expressed and Asymmetrically Segregated in Neural Progenitor Cells at the Transition to Neurogenic Divisions
inferredcites →https://doi.org/10.1006/geno.1996.0636openalex-snapshot
Isolation of Human and Murine Homologues of theDrosophilaMinibrain Gene: Human Homologue Maps to 21q22.2 in the Down Syndrome “Critical Region”
inferredcites →https://doi.org/10.1006/geno.1999.5775openalex-snapshot
HumanMinibrainHomologue (MNBH/DYRK1): Characterization, Alternative Splicing, Differential Tissue Expression, and Overexpression in Down Syndrome
inferredcites →https://doi.org/10.1006/scdb.1998.0266openalex-snapshot
Notch signalling and the control of cell fate choices in vertebrates
inferredcites →https://doi.org/10.1007/978-3-7091-6721-2_11openalex-snapshot
The MNB/DYRK1A protein kinase: Neurobiological functions and Down syndrome implications
inferredcites →https://doi.org/10.1007/978-3-7091-6721-2_12openalex-snapshot
The MNB/DYRK1A protein kinase: Genetic and biochemical properties
inferredcites →https://doi.org/10.1007/bf01243366openalex-snapshot
Influence of photoperiod on dense-core vesicles and synaptic ribbons of pinealocytes of the Djungarian hamster (Phodopus sungorus)
inferredcites →https://doi.org/10.1007/s00018-009-0123-2openalex-snapshot
Function and regulation of Dyrk1A: towards understanding Down syndrome
inferredcites →https://doi.org/10.1016/0361-9230(86)90074-2openalex-snapshot
The neurobiologie consequences of down syndrome
inferredcites →https://doi.org/10.1016/0896-6273(95)90286-4openalex-snapshot
minibrain: A new protein kinase family involved in postembryonic neurogenesis in Drosophila
inferredcites →https://doi.org/10.1016/j.aanat.2008.05.007openalex-snapshot
Reduced cell number in the neocortical part of the human fetal brain in Down syndrome
inferredcites →https://doi.org/10.1016/j.ajhg.2008.03.001openalex-snapshot
Truncation of the Down Syndrome Candidate Gene DYRK1A in Two Unrelated Patients with Microcephaly
inferredcites →https://doi.org/10.1016/j.ceb.2005.09.006openalex-snapshot
Cellular and molecular control of neurogenesis in the mammalian telencephalon
inferredcites →https://doi.org/10.1016/j.ceb.2009.08.009openalex-snapshot
Dynamic regulation of Notch signaling in neural progenitor cells
inferredcites →https://doi.org/10.1016/j.conb.2009.04.003openalex-snapshot
Cell types to order: temporal specification of CNS stem cells
inferredcites →https://doi.org/10.1016/j.devcel.2008.10.014openalex-snapshot
The Protein Kinase DYRK1A Regulates Caspase-9-Mediated Apoptosis during Retina Development
inferredcites →https://doi.org/10.1016/j.mcn.2007.07.007openalex-snapshot
Dyrk1A overexpression in immortalized hippocampal cells produces the neuropathological features of Down syndrome
inferredcites →https://doi.org/10.1016/j.neuron.2005.06.032openalex-snapshot
G1 Phase Regulation, Area-Specific Cell Cycle Control, and Cytoarchitectonics in the Primate Cortex
inferredcites →https://doi.org/10.1016/j.neuroscience.2008.09.034openalex-snapshot
The down syndrome candidate dual-specificity tyrosine phosphorylation-regulated kinase 1A phosphorylates the neurodegeneration-related septin 4
inferredcites →https://doi.org/10.1016/j.pneurobio.2003.12.005openalex-snapshot
Cell cycle regulation of neuronal apoptosis in development and disease
inferredcites →https://doi.org/10.1016/j.stem.2010.06.021openalex-snapshot
Regulated Segregation of Kinase Dyrk1A during Asymmetric Neural Stem Cell Division Is Critical for EGFR-Mediated Biased Signaling
inferredcites →https://doi.org/10.1016/j.ydbio.2005.03.017openalex-snapshot
A novel hes5/hes6 circuitry of negative regulation controls Notch activity during neurogenesis
inferredcites →https://doi.org/10.1016/j.ydbio.2006.10.035openalex-snapshot
A cell-autonomous requirement for Cip/Kip cyclin-kinase inhibitors in regulating neuronal cell cycle exit but not differentiation in the developing spinal cord
inferredcites →https://doi.org/10.1016/j.ydbio.2007.02.012openalex-snapshot
The on/off of Pax6 controls the tempo of neuronal differentiation in the developing spinal cord
inferredcites →https://doi.org/10.1016/s0006-291x(03)00148-7openalex-snapshot
Unusual function of the activation loop in the protein kinase DYRK1A
inferredcites →https://doi.org/10.1016/s0021-9258(19)36694-3openalex-snapshot
Molecular characterization of a rat negative regulator with a basic helix-loop-helix structure predominantly expressed in the developing nervous system.
inferredcites →https://doi.org/10.1016/s0092-8674(00)81239-8openalex-snapshot
A Syndrome of Multiorgan Hyperplasia with Features of Gigantism, Tumorigenesis, and Female Sterility in p27 -Deficient Mice
inferredcites →https://doi.org/10.1016/s0165-0270(02)00278-9openalex-snapshot
A method for pulse and chase BrdU-labeling of early chick embryos
inferredcites →https://doi.org/10.1016/s0736-5748(00)00093-9openalex-snapshot
Neurogenesis in the vertebrate neural tube
inferredcites →https://doi.org/10.1016/s0896-6273(03)00632-9openalex-snapshot
Neurogenesis and the Cell Cycle
inferredcites →https://doi.org/10.1016/s0959-4388(03)00005-9openalex-snapshot
Cell cycle and cell fate interactions in neural development
inferredcites →https://doi.org/10.1016/s0959-4388(03)00015-1openalex-snapshot
Induction and patterning of neuronal development, and its connection to cell cycle control
inferredcites →https://doi.org/10.1016/s0960-9822(06)00293-4openalex-snapshot
Maintenance of neuroepithelial progenitor cells by Delta–Notch signalling in the embryonic chick retina
inferredcites →https://doi.org/10.1016/s0960-9822(06)00360-5openalex-snapshot
Neuronal specification: Generating diversity in the spinal cord
inferredcites →https://doi.org/10.1021/bi060632jopenalex-snapshot
Kinetic Properties of a MNB/DYRK1A Mutant Suitable for the Elucidation of Biochemical Pathways
inferredcites →https://doi.org/10.1038/375761a0openalex-snapshot
Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta
inferredcites →https://doi.org/10.1038/nn1475openalex-snapshot
Notch signaling in the mammalian central nervous system: insights from mouse mutants
inferredcites →https://doi.org/10.1038/nrn1847openalex-snapshot
Notch signalling in vertebrate neural development
inferredcites →https://doi.org/10.1042/bj20021535openalex-snapshot
The specificities of protein kinase inhibitors: an update
inferredcites →https://doi.org/10.1042/bj20070797openalex-snapshot
The selectivity of protein kinase inhibitors: a further update
inferredcites →https://doi.org/10.1046/j.1460-9568.2003.02665.xopenalex-snapshot
Expression patterns and subcellular localization of the Down syndrome candidate protein MNB/DYRK1A suggest a role in late neuronal differentiation
inferredcites →https://doi.org/10.1056/nejm198411013111818openalex-snapshot
Hyperkalemia during Anesthesia
inferredcites →https://doi.org/10.1056/nejm198411013111819openalex-snapshot
Evidence of Arrest of Neurogenesis and Synaptogenesis in Brains of Patients with Down's Syndrome
inferredcites →https://doi.org/10.1073/pnas.111051398openalex-snapshot
Overexpression of p27 Kip1 lengthens the G 1 phase in a mouse model that targets inducible gene expression to central nervous system progenitor cells
inferredcites →https://doi.org/10.1074/jbc.273.40.25893openalex-snapshot
Sequence Characteristics, Subcellular Localization, and Substrate Specificity of DYRK-related Kinases, a Novel Family of Dual Specificity Protein Kinases
inferredcites →https://doi.org/10.1074/jbc.m104091200openalex-snapshot
Protein Kinase Dyrk1 Activates cAMP Response Element-binding Protein during Neuronal Differentiation in Hippocampal Progenitor Cells
inferredcites →https://doi.org/10.1074/jbc.m110.147520openalex-snapshot
Dyrk1A Phosphorylates p53 and Inhibits Proliferation of Embryonic Neuronal Cells
inferredcites →https://doi.org/10.1074/jbc.m400479200openalex-snapshot
The Cyclin-dependent Kinase Inhibitor p27Kip1 Is Stabilized in G0 by Mirk/dyrk1B Kinase
inferredcites →https://doi.org/10.1091/mbc.e04-12-1085openalex-snapshot
DYRK1A Enhances the Mitogen-activated Protein Kinase Cascade in PC12 Cells by Forming a Complex with Ras, B-Raf, and MEK1
inferredcites →https://doi.org/10.1093/cercor/13.6.592openalex-snapshot
Cell Output, Cell Cycle Duration and Neuronal Specification: a Model of Integrated Mechanisms of the Neocortical Proliferative Process
inferredcites →https://doi.org/10.1093/hmg/10.18.1915openalex-snapshot
Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome
inferredcites →https://doi.org/10.1093/hmg/5.9.1305openalex-snapshot
A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region
inferredcites →https://doi.org/10.1093/jnen/63.5.429openalex-snapshot
Transgenic Mouse In Vivo Library of Human Down Syndrome Critical Region 1
inferredcites →https://doi.org/10.1093/nar/17.15.6418openalex-snapshot
Eukaryotic expression vectors for the analysis of mutant proteins
inferredcites →https://doi.org/10.1100/tsw.2006.319openalex-snapshot
DYRK1A (Dual-Specificity Tyrosine-Phosphorylated and -Regulated Kinase 1A): A Gene with Dosage Effect During Development and Neurogenesis
inferredcites →https://doi.org/10.1101/gad.13.12.1501openalex-snapshot
CDK inhibitors: positive and negative regulators of G1-phase progression
inferredcites →https://doi.org/10.1101/gad.377106openalex-snapshot
p27 kip1 independently promotes neuronal differentiation and migration in the cerebral cortex
inferredcites →https://doi.org/10.1111/j.1460-9568.2008.06092.xopenalex-snapshot
The spatio‐temporal and subcellular expression of the candidate Down syndrome gene Mnb/Dyrk1A in the developing mouse brain suggests distinct sequential roles in neuronal development
inferredcites →https://doi.org/10.1111/j.1742-4658.2009.07346.xopenalex-snapshot
Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation
inferredcites →https://doi.org/10.1111/j.1742-4658.2010.07954.xopenalex-snapshot
MNB/DYRK1A as a multiple regulator of neuronal development
inferredcites →https://doi.org/10.1111/j.1742-4658.2010.07955.xopenalex-snapshot
The role of DYRK1A in neurodegenerative diseases
inferredcites →https://doi.org/10.1111/j.1742-4658.2010.07956.xopenalex-snapshot
Activation, regulation, and inhibition of DYRK1A
inferredcites →https://doi.org/10.1111/j.1750-3639.2007.00113.xopenalex-snapshot
RESEARCH ARTICLE: Neurogenesis Impairment and Increased Cell Death Reduce Total Neuron Number in the Hippocampal Region of Fetuses with Down Syndrome
inferredcites →https://doi.org/10.1126/science.1350865openalex-snapshot
Early Stages of Motor Neuron Differentiation Revealed by Expression of Homeobox Gene Islet-1
inferredcites →https://doi.org/10.1128/mcb.22.18.6636-6647.2002openalex-snapshot
Dyrk1A Haploinsufficiency Affects Viability and Causes Developmental Delay and Abnormal Brain Morphology in Mice
inferredcites →https://doi.org/10.1146/annurev.cellbio.042308.113259openalex-snapshot
From Progenitors to Differentiated Cells in the Vertebrate Retina
inferredcites →https://doi.org/10.1159/000082138openalex-snapshot
Altered Patterns of Neuron Production in the p27Kip1 Knockout Mouse
inferredcites →https://doi.org/10.1159/000334144openalex-snapshot
Anorexigenic and Orexigenic Hormone Modulation of Mammalian Target of Rapamycin Complex 1 Activity and the Regulation of Hypothalamic Agouti-Related Protein mRNA Expression
inferredcites →https://doi.org/10.1159/000472398openalex-snapshot
Molecular Mapping of Twenty-Four Features of Down Syndrome on Chromosome 21
inferredcites →https://doi.org/10.1186/1471-2121-4-12openalex-snapshot
Overexpression of the human MNB/DYRK1A gene induces formation of multinucleate cells through overduplication of the centrosome
inferredcites →https://doi.org/10.1242/dev.006379openalex-snapshot
Spatial and temporal specification of neural fates by transcription factor codes
inferredcites →https://doi.org/10.1242/dev.00840openalex-snapshot
Ebf gene function is required for coupling neuronal differentiation and cell cycle exit
inferredcites →https://doi.org/10.1242/dev.122.8.2465openalex-snapshot
The intracellular deletions of DELTA and SERRATE define dominant negative forms of the Drosophila Notch ligands
inferredcites →https://doi.org/10.1242/dev.129.9.2087openalex-snapshot
A mitogen gradient of dorsal midline Wnts organizes growth in the CNS
inferredcites →https://doi.org/10.1242/jcs.044354openalex-snapshot
Attenuation of Notch signalling by the Down-syndrome-associated kinase DYRK1A
inferredcites →https://doi.org/10.1371/journal.pone.0001169openalex-snapshot
A Novel Function of DELTA-NOTCH Signalling Mediates the Transition from Proliferation to Neurogenesis in Neural Progenitor Cells
inferredcites →https://doi.org/10.1371/journal.pone.0004606openalex-snapshot
Green Tea Polyphenols Rescue of Brain Defects Induced by Overexpression of DYRK1A
inferredcites →https://doi.org/10.1523/jneurosci.0778-05.2005openalex-snapshot
Selective Lengthening of the Cell Cycle in the Neurogenic Subpopulation of Neural Progenitor Cells during Mouse Brain Development
inferredcites →https://doi.org/10.1523/jneurosci.3406-07.2007openalex-snapshot
Defects in Embryonic Neurogenesis and Initial Synapse Formation in the Forebrain of the Ts65Dn Mouse Model of Down Syndrome
inferredcites →https://doi.org/10.1523/jneurosci.4711-09.2010openalex-snapshot
Dyrk1A Overexpression Inhibits Proliferation and Induces Premature Neuronal Differentiation of Neural Progenitor Cells
inferredcites →https://doi.org/10.4161/cc.5.20.3381openalex-snapshot
Coupling Cell Cycle Exit, Neuronal Differentiation and Migration in Cortical Neurogenesis
inferredcites →https://doi.org/10.4161/cc.9.3.10762openalex-snapshot
Timing neurogenesis by cell cycle?
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4669820openalex-extracted
Dyrk1a is Required for Craniofacial Development in Xenopus Laevis
inferred← citeshttps://doi.org/10.1002/cbin.10694openalex-snapshot
Generation of improved human cerebral organoids from single copy DYRK1A knockout induced pluripotent stem cells in trisomy 21: hypothetical solutions for neurodevelopmental models and therapeutic alternatives in down syndrome
inferred← citeshttps://doi.org/10.1002/dneu.22798openalex-snapshot
Role of PTHrP nuclear localization and carboxyl terminus sequences in postnatal spinal cord development
inferred← citeshttps://doi.org/10.1002/emmm.201302848openalex-snapshot
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21
inferred← citeshttps://doi.org/10.1002/jnr.23007openalex-snapshot
Effect of DYRK1A activity inhibition on development of neuronal progenitors isolated from Ts65Dn mice
inferred← citeshttps://doi.org/10.1007/978-3-031-89307-0_19openalex-snapshot
Down Syndrome: Progress in Defining Pathogenesis and Treatments for Neurodevelopmental Deficits and Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1007/s00018-024-05353-6openalex-snapshot
Neurobiological research on N,N-dimethyltryptamine (DMT) and its potentiation by monoamine oxidase (MAO) inhibition: from ayahuasca to synthetic combinations of DMT and MAO inhibitors
inferred← citeshttps://doi.org/10.1007/s00125-014-3174-3openalex-snapshot
Dyrk1a haploinsufficiency induces diabetes in mice through decreased pancreatic beta cell mass
inferred← citeshttps://doi.org/10.1007/s00412-020-00737-6openalex-snapshot
Molecular causes of primary microcephaly and related diseases: a report from the UNIA Workshop
inferred← citeshttps://doi.org/10.1007/s00726-013-1489-xopenalex-snapshot
Functional implications of hippocampal adult neurogenesis in intellectual disabilities
inferred← citeshttps://doi.org/10.1007/s11914-021-00674-yopenalex-snapshot
Current Analysis of Skeletal Phenotypes in Down Syndrome
inferred← citeshttps://doi.org/10.1007/s12035-025-04806-8openalex-snapshot
Unlocking the Therapeutic Potential of the Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A Inhibitors in Alzheimer’s Diseases
inferred← citeshttps://doi.org/10.1007/s13237-016-0187-yopenalex-snapshot
Down syndrome: from the age of characterization to the era of curative approach
inferred← citeshttps://doi.org/10.1016/b978-0-12-813008-7.00035-7openalex-snapshot
Can Green Tea Polyphenols Improve Phenotypes Associated With Down Syndrome?
inferred← citeshttps://doi.org/10.1016/b978-0-323-90456-8.00002-8openalex-snapshot
Development of specific phenotypes and genetic consequences in Down syndrome
inferred← citeshttps://doi.org/10.1016/b978-0-323-90456-8.00004-1openalex-snapshot
Chromosomal etiology of Down syndrome
inferred← citeshttps://doi.org/10.1016/b978-0-323-90456-8.00005-3openalex-snapshot
Gene-dosage imbalance due to trisomic HSA21 and genotype–phenotype association in Down syndrome
inferred← citeshttps://doi.org/10.1016/bs.pbr.2019.08.001openalex-snapshot
Modeling Down syndrome in animals from the early stage to the 4.0 models and next
inferred← citeshttps://doi.org/10.1016/bs.pbr.2019.09.002openalex-snapshot
Genetic and epigenetic pathways in Down syndrome: Insights to the brain and immune system from humans and mouse models
inferred← citeshttps://doi.org/10.1016/bs.pbr.2019.11.001openalex-snapshot
Plasticity as a therapeutic target for improving cognition and behavior in Down syndrome
inferred← citeshttps://doi.org/10.1016/j.abb.2012.07.017openalex-snapshot
FoxOs in neural stem cell fate decision
inferred← citeshttps://doi.org/10.1016/j.biopsych.2021.01.012openalex-snapshot
Dyrk1a Mutations Cause Undergrowth of Cortical Pyramidal Neurons via Dysregulated Growth Factor Signaling
inferred← citeshttps://doi.org/10.1016/j.cell.2022.11.026openalex-snapshot
A transcription factor atlas of directed differentiation
inferred← citeshttps://doi.org/10.1016/j.ebiom.2015.01.010openalex-snapshot
DYRK1A-mediated Cyclin D1 Degradation in Neural Stem Cells Contributes to the Neurogenic Cortical Defects in Down Syndrome
inferred← citeshttps://doi.org/10.1016/j.ejmech.2021.113911openalex-snapshot
Discovery of novel 6-hydroxybenzothiazole urea derivatives as dual Dyrk1A/α-synuclein aggregation inhibitors with neuroprotective effects
inferred← citeshttps://doi.org/10.1016/j.ejmech.2021.113948openalex-snapshot
Structure-activity relationship for the folding intermediate-selective inhibition of DYRK1A
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2017.07.026openalex-snapshot
Neurogenesis impairment: An early developmental defect in Down syndrome
inferred← citeshttps://doi.org/10.1016/j.gendis.2026.102133openalex-snapshot
Emerging roles of DYRK-mediated DNA damage response in cancer
inferred← citeshttps://doi.org/10.1016/j.genrep.2024.102106openalex-snapshot
Genetic interactions and co-operating effects of non-HSA21 genes on the phenotypic variability in Down syndrome
inferred← citeshttps://doi.org/10.1016/j.molcel.2020.06.021openalex-snapshot
Proline Hydroxylation Primes Protein Kinases for Autophosphorylation and Activation
inferred← citeshttps://doi.org/10.1016/j.nbd.2012.01.007openalex-snapshot
DYRK1A: A master regulatory protein controlling brain growth
inferred← citeshttps://doi.org/10.1016/j.nbd.2013.08.008openalex-snapshot
Environmental enrichment rescues DYRK1A activity and hippocampal adult neurogenesis in TgDyrk1A
inferred← citeshttps://doi.org/10.1016/j.nbd.2017.12.003openalex-snapshot
DYRK1A-haploinsufficiency in mice causes autistic-like features and febrile seizures
inferred← citeshttps://doi.org/10.1016/j.nbd.2023.106359openalex-snapshot
Sex-specific developmental alterations in DYRK1A expression in the brain of a Down syndrome mouse model
inferred← citeshttps://doi.org/10.1016/j.nbd.2026.107379openalex-snapshot
DYRK1A and Parkinson’s disease, facts and hypotheses
inferred← citeshttps://doi.org/10.1016/j.neuron.2020.05.038openalex-snapshot
Direct Readout of Neural Stem Cell Transgenesis with an Integration-Coupled Gene Expression Switch
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2015.03.004openalex-snapshot
DYRK1A in neurodegeneration and cancer: Molecular basis and clinical implications
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2018.09.010openalex-snapshot
DYRK1A and cognition: A lifelong relationship
inferred← citeshttps://doi.org/10.1016/j.tice.2018.10.002openalex-snapshot
Dyrk1A promotes the proliferation, migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis via down-regulating Spry2 and activating the ERK MAPK pathway
inferred← citeshttps://doi.org/10.1016/j.ydbio.2016.12.022openalex-snapshot
Playing with the cell cycle to build the spinal cord
inferred← citeshttps://doi.org/10.1016/j.ydbio.2024.04.004openalex-snapshot
Dyrk1a is required for craniofacial development in Xenopus laevis.
inferred← citeshttps://doi.org/10.1016/j.ydbio.2025.06.009openalex-snapshot
The role of Goldilocks protein kinase DYRK1A in embryonic development
inferred← citeshttps://doi.org/10.1017/cbo9781107360556.010openalex-snapshot
Social dysfunction and mental retardation
inferred← citeshttps://doi.org/10.1021/acschemneuro.1c00475openalex-snapshot
Discovery of Hydroxybenzothiazole Urea Compounds as Multitargeted Agents Suppressing Major Cytotoxic Mechanisms in Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.1038/cddis.2014.253openalex-snapshot
DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson’s disease
inferred← citeshttps://doi.org/10.1038/ejhg.2015.29openalex-snapshot
Ten new cases further delineate the syndromic intellectual disability phenotype caused by mutations in DYRK1A
inferred← citeshttps://doi.org/10.1038/leu.2016.164openalex-snapshot
The biology, pathogenesis and clinical aspects of acute lymphoblastic leukemia in children with Down syndrome
inferred← citeshttps://doi.org/10.1038/nature16475openalex-snapshot
An ID2-dependent mechanism for VHL inactivation in cancer
inferred← citeshttps://doi.org/10.1038/ncomms9023openalex-snapshot
Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1
inferred← citeshttps://doi.org/10.1038/ncomms9894openalex-snapshot
Aneuploidy causes premature differentiation of neural and intestinal stem cells
inferred← citeshttps://doi.org/10.1038/nrc3355openalex-snapshot
Tumorigenesis in Down's syndrome: big lessons from a small chromosome
inferred← citeshttps://doi.org/10.1038/nrn3314openalex-snapshot
Down syndrome: the brain in trisomic mode
inferred← citeshttps://doi.org/10.1038/s41380-025-03109-7openalex-snapshot
Interneuron migration defects during corticogenesis contribute to Dyrk1a haploinsufficiency syndrome pathogenesis
inferred← citeshttps://doi.org/10.1038/s41598-017-05407-9openalex-snapshot
The alkaloids of Banisteriopsis caapi, the plant source of the Amazonian hallucinogen Ayahuasca, stimulate adult neurogenesis in vitro
inferred← citeshttps://doi.org/10.1038/s41598-019-42990-5openalex-snapshot
The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair
inferred← citeshttps://doi.org/10.1038/s41598-019-43820-4openalex-snapshot
Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus
inferred← citeshttps://doi.org/10.1038/s41598-025-23431-yopenalex-snapshot
Identification of novel DYRK1A inhibitors as treatment options for alzheimer’s disease through comprehensive in silico approaches
inferred← citeshttps://doi.org/10.1038/s42003-021-02242-7openalex-snapshot
A human isogenic iPSC-derived cell line panel identifies major regulators of aberrant astrocyte proliferation in Down syndrome
inferred← citeshttps://doi.org/10.1073/pnas.2517506123openalex-snapshot
Up-regulation of Minibrain/DYRK1A contributes to macrocephaly and brain overgrowth in a Drosophila model of fragile X syndrome
inferred← citeshttps://doi.org/10.1074/jbc.m115.675751openalex-snapshot
HIV-1-Tat Protein Inhibits SC35-mediated Tau Exon 10 Inclusion through Up-regulation of DYRK1A Kinase
inferred← citeshttps://doi.org/10.1074/jbc.m116.717553openalex-snapshot
E3 Ligase SCFβTrCP-induced DYRK1A Protein Degradation Is Essential for Cell Cycle Progression in HEK293 Cells
inferred← citeshttps://doi.org/10.1080/01677063.2018.1438427openalex-snapshot
Mnb/Dyrk1Aorchestrates a transcriptional network at the transition from self-renewing neurogenic progenitors to postmitotic neuronal precursors
inferred← citeshttps://doi.org/10.1084/jem.20150002openalex-snapshot
DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3
inferred← citeshttps://doi.org/10.1089/scd.2017.0139openalex-snapshot
DYRK1A Is a Regulator of S-Phase Entry in Hepatic Progenitor Cells
inferred← citeshttps://doi.org/10.1093/cvr/cvw074openalex-snapshot
Dyrk1a regulates the cardiomyocyte cell cycle via D-cyclin-dependent Rb/E2f-signalling
inferred← citeshttps://doi.org/10.1093/hmg/dds052openalex-snapshot
OLIG2 over-expression impairs proliferation of human Down syndrome neural progenitors
inferred← citeshttps://doi.org/10.1093/hmg/ddt446openalex-snapshot
Human chromosome 21 orthologous region on mouse chromosome 17 is a major determinant of Down syndrome-related developmental cognitive deficits
inferred← citeshttps://doi.org/10.1093/hmg/ddv284openalex-snapshot
Rescue of the abnormal skeletal phenotype in Ts65Dn Down syndrome mice using genetic and therapeutic modulation of trisomicDyrk1a
inferred← citeshttps://doi.org/10.1093/hmg/ddv364openalex-snapshot
Genetic dissection of the Down syndrome critical region
inferred← citeshttps://doi.org/10.1093/hmg/ddw309openalex-snapshot
Influence of prenatal EGCG treatment andDyrk1adosage reduction on craniofacial features associated with Down syndrome
inferred← citeshttps://doi.org/10.1093/nar/gky754openalex-snapshot
DYRK1A interacts with histone acetyl transferase p300 and CBP and localizes to enhancers
inferred← citeshttps://doi.org/10.1101/2021.06.16.448740openalex-snapshot
Proteomic changes induced by harmine in human brain organoids reveal signaling pathways related to neuroprotection
inferred← citeshttps://doi.org/10.1101/2023.11.09.566424openalex-snapshot
Interneuron migration defects during corticogenesis contribute to Dyrk1a haploinsufficiency syndrome pathogenesis via actomyosin dynamics deregulations
inferred← citeshttps://doi.org/10.1101/2025.04.14.648790openalex-snapshot
Regulation of FGF/MAPK signaling at the primary cilium base controls the proliferation-neurogenesis balance in human cerebellar organoids
inferred← citeshttps://doi.org/10.1101/315317openalex-snapshot
Cerebral organoid proteomics reveals signatures of dysregulated cortical development associated with human trisomy 21
inferred← citeshttps://doi.org/10.1111/cbdd.70366openalex-snapshot
Integrative Insights Into DYRK1A From Molecular Function to Therapeutic Advancement
inferred← citeshttps://doi.org/10.1155/2012/171639openalex-snapshot
Molecular and Cellular Alterations in Down Syndrome: Toward the Identification of Targets for Therapeutics
inferred← citeshttps://doi.org/10.1155/2019/2054783openalex-snapshot
Cend1, a Story with Many Tales: From Regulation of Cell Cycle Progression/Exit of Neural Stem Cells to Brain Structure and Function
inferred← citeshttps://doi.org/10.1186/s13068-019-1635-0openalex-snapshot
Nitrogen-dependent coordination of cell cycle, quiescence and TAG accumulation in Chlamydomonas
inferred← citeshttps://doi.org/10.1210/en.2014-1329openalex-snapshot
DYRK1A BAC Transgenic Mouse: A New Model of Thyroid Dysgenesis in Down Syndrome
inferred← citeshttps://doi.org/10.1210/endocr/bqab128openalex-snapshot
Integrated Analysis of Transcriptome and Histone Modifications in Granulosa Cells During Ovulation in Female Mice
inferred← citeshttps://doi.org/10.1242/bio.032862openalex-snapshot
Functional characterization of DYRK1A missense variants associated with a syndromic form of intellectual deficiency and autism
inferred← citeshttps://doi.org/10.1242/dev.076406openalex-snapshot
Regulation of neuronal differentiation at the neurogenic wavefront
inferred← citeshttps://doi.org/10.1242/dev.134338openalex-snapshot
Minibrain drives the Dacapo dependent cell cycle exit of neurons in the Drosophila brain by promoting asense and prospero expression
inferred← citeshttps://doi.org/10.1242/dev.171298openalex-snapshot
A TOR-YAK1 signaling axis controls cell cycle, meristem activity and plant growth in Arabidopsis
inferred← citeshttps://doi.org/10.1242/dmm.008078openalex-snapshot
Down syndrome: searching for the genetic culprits
inferred← citeshttps://doi.org/10.1242/dmm.052740openalex-snapshot
Leucettinib-21 decreases dosage effects of DYRK1A in human trisomy 21 induced pluripotent stem cell-derived neural cells
inferred← citeshttps://doi.org/10.1371/journal.pgen.1009777openalex-snapshot
Dyrk1a gene dosage in glutamatergic neurons has key effects in cognitive deficits observed in mouse models of MRD7 and Down syndrome
inferred← citeshttps://doi.org/10.1371/journal.pone.0076775openalex-snapshot
Drosophila Dyrk2 Plays a Role in the Development of the Visual System
inferred← citeshttps://doi.org/10.1371/journal.pone.0082172openalex-snapshot
Functional Interactions between BM88/Cend1, Ran-Binding Protein M and Dyrk1B Kinase Affect Cyclin D1 Levels and Cell Cycle Progression/Exit in Mouse Neuroblastoma Cells
inferred← citeshttps://doi.org/10.1371/journal.pone.0098853openalex-snapshot
Tumor Suppressor DYRK1A Effects on Proliferation and Chemoresistance of AML Cells by Downregulating c-Myc
inferred← citeshttps://doi.org/10.14201/gredos.124163openalex-snapshot
Efecto del factor neurotrófico ácido oleico en modelos celulares de síndrome de Down
inferred← citeshttps://doi.org/10.15252/embr.202255764openalex-snapshot
The mitochondrial ribosomal protein mRpL4 regulates Notch signaling
inferred← citeshttps://doi.org/10.2174/0929867329666220620162018openalex-snapshot
DYRK1A Inhibitors and Perspectives for the Treatment of Alzheimer's Disease
inferred← citeshttps://doi.org/10.3389/fgene.2022.1007519openalex-snapshot
Biphasic cell cycle defect causes impaired neurogenesis in down syndrome
inferred← citeshttps://doi.org/10.3389/fnbeh.2016.00104openalex-snapshot
DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome
inferred← citeshttps://doi.org/10.3389/fncel.2022.903729openalex-snapshot
The Challenging Pathway of Treatment for Neurogenesis Impairment in Down Syndrome: Achievements and Perspectives
inferred← citeshttps://doi.org/10.3389/fphar.2016.00119openalex-snapshot
E2F4 Promotes Neuronal Regeneration and Functional Recovery after Spinal Cord Injury in Zebrafish
inferred← citeshttps://doi.org/10.3390/brainsci8100187openalex-snapshot
DYRK1A Protein, A Promising Therapeutic Target to Improve Cognitive Deficits in Down Syndrome
inferred← citeshttps://doi.org/10.3390/cancers14082034openalex-snapshot
A Bioinformatics Evaluation of the Role of Dual-Specificity Tyrosine-Regulated Kinases in Colorectal Cancer
inferred← citeshttps://doi.org/10.3390/genes12111833openalex-snapshot
Dyrk1a from Gene Function in Development and Physiology to Dosage Correction across Life Span in Down Syndrome
inferred← citeshttps://doi.org/10.3390/ijms21186906openalex-snapshot
Signalling Pathways Implicated in Alzheimer′s Disease Neurodegeneration in Individuals with and without Down Syndrome
inferred← citeshttps://doi.org/10.3390/ijms22084011openalex-snapshot
DYRK1A Negatively Regulates CDK5-SOX2 Pathway and Self-Renewal of Glioblastoma Stem Cells
inferred← citeshttps://doi.org/10.3390/ijms22169098openalex-snapshot
GSK-3β, FYN, and DYRK1A: Master Regulators in Neurodegenerative Pathways
inferred← citeshttps://doi.org/10.3390/ijms26168092openalex-snapshot
Vertebrate and Invertebrate Animal Models for the Study of Down Syndrome
inferred← citeshttps://doi.org/10.3390/molecules24224090openalex-snapshot
[b]-Annulated Halogen-Substituted Indoles as Potential DYRK1A Inhibitors
inferred← citeshttps://doi.org/10.3892/or.2017.5952openalex-snapshot
Harmine suppresses the proliferation and migration of human ovarian cancer cells through inhibiting ERK/CREB pathway
inferred← citeshttps://doi.org/10.4161/23723548.2014.970048openalex-snapshot
DYRK1A: the double-edged kinase as a protagonist in cell growth and tumorigenesis
inferred← citeshttps://doi.org/10.4161/cc.21404openalex-snapshot
Emerging role of DYRK family protein kinases as regulators of protein stability in cell cycle control
inferred← citeshttps://doi.org/10.4161/cc.29104openalex-snapshot
The Down syndrome-related protein kinase DYRK1A phosphorylates p27Kip1and Cyclin D1 and induces cell cycle exit and neuronal differentiation
inferred← citeshttps://doi.org/10.5483/bmbrep.2023-0165openalex-snapshot
Regulation of CMGC kinases by hypoxia
inferred← citeshttps://doi.org/10.5772/53000openalex-snapshot
Molecular Pathways of Down Syndrome Critical Region Genes
inferred← citeshttps://doi.org/10.64898/2026.03.15.710015openalex-snapshot
Dyrk1a gene dosage controls bipolar cell development and retinal connectivity
inferred← citeshttps://doi.org/10.64898/2026.05.13.724917openalex-snapshot
LONG-TERM NEURODEVELOPMENTAL AND COGNITIVE OUTCOMES FOLLOWING PRENATAL INHIBITION OF DYRK1A BY LEUCETTINE L41 IN MOUSE MODELS OF DOWN SYNDROME
inferred← citeshttps://doi.org/10.70675/33564daaz45bdz4a59z9a5bz6f4342742254openalex-snapshot
Etude des mécanismes moléculaires impliqués dans le cycle cellulaire des cellules β pancréatiques humaines
inferred← citeshttps://doi.org/10.70675/8ad2fe6ez1c11z474czae8ez75a7635dadb2openalex-snapshot
Étude des relations entre la prolifération et la différenciation cellulaire au cours de l'organogenèse intestinale chez C. elegans
inferred← citeshttps://doi.org/10.70675/997f5617z31f4z4560za123z7d7cd6b24f2aopenalex-snapshot
Design, synthèse et étude biologique de dérivés à structure imidazo[4,5-c]-1,6-naphtyridin-2(1H)-one et analogues structuraux à visée antiproliférative
inferred← citeshttps://doi.org/10.70675/ac74aea3z1c11z4272z8737z57c293c54614openalex-snapshot
Recherches de biomarqueurs impliqués dans la maladie d’Alzheimer et associés à la protéine DYRK1A dans le syndrome de Down pour valider des traitements potentiels
inferred← citeshttps://doi.org/10.70675/f15d5957z45d3z4384zb0dbze345ee20e930openalex-snapshot
Étude du lignage des cellules progénitrices rétiniennes chez le poulet : origine des classes et types neuronaux
inferred← citeshttps://doi.org/10.7287/peerj.2727v0.1/reviews/1openalex-snapshot
Peer Review #1 of "Harmine stimulates proliferation of human neural progenitors (v0.1)"
inferred← citeshttps://doi.org/10.7287/peerj.2727v0.1/reviews/2openalex-snapshot
Peer Review #2 of "Harmine stimulates proliferation of human neural progenitors (v0.1)"
inferred← citeshttps://doi.org/10.7287/peerj.2727v0.2/reviews/1openalex-snapshot
Peer Review #1 of "Harmine stimulates proliferation of human neural progenitors (v0.2)"
inferred← citeshttps://doi.org/10.7287/peerj.2727v0.2/reviews/2openalex-snapshot
Peer Review #2 of "Harmine stimulates proliferation of human neural progenitors (v0.2)"
inferred← citeshttps://doi.org/10.7287/peerj.preprints.1957v1openalex-snapshot
Harmine stimulates neurogenesis of human neural cells in vitro
inferred← citeshttps://doi.org/10.7554/elife.24502openalex-snapshot
Inhibition of DYRK1A disrupts neural lineage specificationin human pluripotent stem cells
inferred← citeshttps://doi.org/10.7554/elife.31543openalex-snapshot
Alterations of in vivo CA1 network activity in Dp(16)1Yey Down syndrome model mice
inferred← citeshttps://doi.org/10.7554/elife.88318openalex-snapshot
DYRK1A interacts with the tuberous sclerosis complex and promotes mTORC1 activity
inferred← citeshttps://doi.org/10.7554/elife.88318.1openalex-snapshot
DYRK1A Interacts with the Tuberous Sclerosis Complex and Promotes mTORC1 Activity
inferred← citeshttps://doi.org/10.7554/elife.88318.2openalex-snapshot
DYRK1A Interacts with the Tuberous Sclerosis Complex and Promotes mTORC1 Activity
inferred← citeshttps://doi.org/10.7554/elife.88318.3openalex-snapshot
DYRK1A interacts with the tuberous sclerosis complex and promotes mTORC1 activity
inferred← citeshttps://doi.org/10.7717/peerj.2727openalex-snapshot
Harmine stimulates proliferation of human neural progenitors
Editorial review for independent work. ICSAC — the Institute for Complexity
Science and Advanced Computing — runs a structured editorial panel for researchers
publishing outside journals, and publishes on CiteStamp rails. Submission is free
and goes through ORCID: icsacinstitute.org/submit.