On the public citation graph
The Protein Kinase DYRK1A Regulates Caspase-9-Mediated Apoptosis during Retina Development
0 signed · 215 inferred · view as graph
Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.
Is this your work? Sign in with ORCID and put your name on the
claims that are yours.
Reference health. See whether every reference in this work resolves to a
known work and none has been retracted — and get a dated CiteStamped
badge you can embed.
What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/1096-9861(20000814)424:1<1::aid-cne1>3.0.co;2-vopenalex-snapshot
Immunocytochemical analysis of the mouse retina
inferredcites →https://doi.org/10.1002/ar.1092120215openalex-snapshot
Cell differentiation in the retina of the mouse
inferredcites →https://doi.org/10.1002/cne.10177openalex-snapshot
Retinal organization in the bcl‐2‐overexpressing transgenic mouse
inferredcites →https://doi.org/10.1002/cne.10985openalex-snapshot
Types of bipolar cells in the mouse retina
inferredcites →https://doi.org/10.1002/cne.20615openalex-snapshot
Cell birth and death in the mouse retinal ganglion cell layer
inferredcites →https://doi.org/10.1002/cne.902290307openalex-snapshot
Cell death during differentiation of the retina in the mouse
inferredcites →https://doi.org/10.1002/dvdy.10376openalex-snapshot
Major role of BAX in apoptosis during retinal development and in establishment of a functional postnatal retina
inferredcites →https://doi.org/10.1002/ijc.22573openalex-snapshot
Increased expression of Dyrk1a in HPV16 immortalized Keratinocytes enable evasion of apoptosis
inferredcites →https://doi.org/10.1002/mrdd.20164openalex-snapshot
Using mouse models to explore genotype–phenotype relationship in Down syndrome
inferredcites →https://doi.org/10.1006/dbio.2002.0675openalex-snapshot
Mnb/Dyrk1A Is Transiently Expressed and Asymmetrically Segregated in Neural Progenitor Cells at the Transition to Neurogenic Divisions
inferredcites →https://doi.org/10.1006/geno.1996.0636openalex-snapshot
Isolation of Human and Murine Homologues of theDrosophilaMinibrain Gene: Human Homologue Maps to 21q22.2 in the Down Syndrome “Critical Region”
inferredcites →https://doi.org/10.1006/geno.1999.5775openalex-snapshot
HumanMinibrainHomologue (MNBH/DYRK1): Characterization, Alternative Splicing, Differential Tissue Expression, and Overexpression in Down Syndrome
inferredcites →https://doi.org/10.1007/978-1-4899-1549-8_7openalex-snapshot
The Origin of the Major Rod- and Cone-Driven Components of the Rodent Electroretinogram and the Effect of Age and Light-Rearing History on the Magnitude of These Components
inferredcites →https://doi.org/10.1007/s004410000178openalex-snapshot
Apoptosis in the developing visual system
inferredcites →https://doi.org/10.1016/0165-0270(91)90106-aopenalex-snapshot
A useful programme in BASIC for axonal morphometry with introduction of new cytoskeletal parameters
inferredcites →https://doi.org/10.1016/0896-6273(94)90354-9openalex-snapshot
Developmental expression of a novel murine homeobox gene (Chx10): Evidence for roles in determination of the neuroretina and inner nuclear layer
inferredcites →https://doi.org/10.1016/0896-6273(95)90286-4openalex-snapshot
minibrain: A new protein kinase family involved in postembryonic neurogenesis in Drosophila
inferredcites →https://doi.org/10.1016/j.ajhg.2008.03.001openalex-snapshot
Truncation of the Down Syndrome Candidate Gene DYRK1A in Two Unrelated Patients with Microcephaly
inferredcites →https://doi.org/10.1016/j.brainres.2004.03.008openalex-snapshot
Cell type- and brain structure-specific patterns of distribution of minibrain kinase in human brain
inferredcites →https://doi.org/10.1016/j.cell.2005.03.034openalex-snapshot
Activation-Loop Autophosphorylation Is Mediated by a Novel Transitional Intermediate Form of DYRKs
inferredcites →https://doi.org/10.1016/j.ejpn.2007.08.010openalex-snapshot
Mental retardation and associated neurological dysfunctions in Down syndrome: A consequence of dysregulation in critical chromosome 21 genes and associated molecular pathways
inferredcites →https://doi.org/10.1016/j.molcel.2007.03.019openalex-snapshot
Phosphorylation of Caspase-9 by CDK1/Cyclin B1 Protects Mitotic Cells against Apoptosis
inferredcites →https://doi.org/10.1016/j.nbd.2005.02.004openalex-snapshot
Alterations in the phenotype of neocortical pyramidal cells in the Dyrk1A+/− mouse
inferredcites →https://doi.org/10.1016/j.neuron.2004.08.032openalex-snapshot
The Transcription Factor Bhlhb4 Is Required for Rod Bipolar Cell Maturation
inferredcites →https://doi.org/10.1016/j.semcdb.2005.02.012openalex-snapshot
Regulation of proliferation during central nervous system development
inferredcites →https://doi.org/10.1016/s0006-8993(02)04069-6openalex-snapshot
Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system
inferredcites →https://doi.org/10.1016/s0042-6989(01)00146-8openalex-snapshot
Retinal degeneration mutants in the mouse
inferredcites →https://doi.org/10.1016/s0079-6603(08)60503-6openalex-snapshot
Structural and Functional Characteristics of Dyrk, a Novel Subfamily of Protein Kinases with Dual Specificity
inferredcites →https://doi.org/10.1016/s0092-8674(00)81476-2openalex-snapshot
Reduced Apoptosis and Cytochrome c–Mediated Caspase Activation in Mice Lacking Caspase 9
inferredcites →https://doi.org/10.1016/s0092-8674(00)81477-4openalex-snapshot
Differential Requirement for Caspase 9 in Apoptotic Pathways In Vivo
inferredcites →https://doi.org/10.1016/s0166-2236(00)01637-4openalex-snapshot
Live or let die – retinal ganglion cell death and survival during development and in the lesioned adult CNS
inferredcites →https://doi.org/10.1016/s0166-2236(00)02028-2openalex-snapshot
Generating neuronal diversity in the retina: one for nearly all
inferredcites →https://doi.org/10.1016/s0896-6273(01)00436-6openalex-snapshot
The Reelin Pathway Modulates the Structure and Function of Retinal Synaptic Circuitry
inferredcites →https://doi.org/10.1016/s0959-437x(97)80013-5openalex-snapshot
Cellular diversification in the vertebrate retina
inferredcites →https://doi.org/10.1016/s0959-4388(99)80005-1openalex-snapshot
The roles of intrinsic and extrinsic cues and bHLH genes in the determination of retinal cell fates
inferredcites →https://doi.org/10.1016/s1350-9462(03)00027-2openalex-snapshot
Molecular determinants of retinal ganglion cell development, survival, and regeneration
inferredcites →https://doi.org/10.1037/0735-7044.118.4.815openalex-snapshot
Haploinsufficiency of Dyrk1A in Mice Leads to Specific Alterations in the Development and Regulation of Motor Activity.
inferredcites →https://doi.org/10.1038/35053522openalex-snapshot
Vertebrate neural cell-fate determination: Lessons from the retina
inferredcites →https://doi.org/10.1038/78774openalex-snapshot
Control of Müller glial cell proliferation and activation following retinal injury
inferredcites →https://doi.org/10.1038/nature04678openalex-snapshot
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21
inferredcites →https://doi.org/10.1038/ncb1005openalex-snapshot
Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK
inferredcites →https://doi.org/10.1038/ncb1258openalex-snapshot
Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
inferredcites →https://doi.org/10.1038/ng0597-28openalex-snapshot
Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome
inferredcites →https://doi.org/10.1038/nrm2153openalex-snapshot
The apoptosome: signalling platform of cell death
inferredcites →https://doi.org/10.1038/sj.cdd.4402034openalex-snapshot
Caspase inhibitors: viral, cellular and chemical
inferredcites →https://doi.org/10.1038/sj.cdd.4402060openalex-snapshot
Caspase function in programmed cell death
inferredcites →https://doi.org/10.1042/bj20070797openalex-snapshot
The selectivity of protein kinase inhibitors: a further update
inferredcites →https://doi.org/10.1073/pnas.93.2.589openalex-snapshot
Cell fate determination in the vertebrate retina.
inferredcites →https://doi.org/10.1074/jbc.275.4.2431openalex-snapshot
Specificity Determinants of Substrate Recognition by the Protein Kinase DYRK1A
inferredcites →https://doi.org/10.1074/jbc.m104091200openalex-snapshot
Protein Kinase Dyrk1 Activates cAMP Response Element-binding Protein during Neuronal Differentiation in Hippocampal Progenitor Cells
inferredcites →https://doi.org/10.1074/jbc.m205374200openalex-snapshot
DYRK3 Activation, Engagement of Protein Kinase A/cAMP Response Element-binding Protein, and Modulation of Progenitor Cell Survival
inferredcites →https://doi.org/10.1074/jbc.m413594200openalex-snapshot
Mirk/Dyrk1B Mediates Survival during the Differentiation of C2C12Myoblasts
inferredcites →https://doi.org/10.1091/mbc.e04-12-1085openalex-snapshot
DYRK1A Enhances the Mitogen-activated Protein Kinase Cascade in PC12 Cells by Forming a Complex with Ras, B-Raf, and MEK1
inferredcites →https://doi.org/10.1091/mbc.e06-08-0668openalex-snapshot
DYRK1A Autophosphorylation on Serine Residue 520 Modulates Its Kinase Activity via 14-3-3 Binding
inferredcites →https://doi.org/10.1093/emboj/20.5.1064openalex-snapshot
Fission yeast Pom1p kinase activity is cell cycle regulated and essential for cellular symmetry during growth and division
inferredcites →https://doi.org/10.1093/hmg/5.9.1305openalex-snapshot
A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region
inferredcites →https://doi.org/10.1093/jnen/63.5.429openalex-snapshot
Transgenic Mouse In Vivo Library of Human Down Syndrome Critical Region 1
inferredcites →https://doi.org/10.1100/tsw.2006.319openalex-snapshot
DYRK1A (Dual-Specificity Tyrosine-Phosphorylated and -Regulated Kinase 1A): A Gene with Dosage Effect During Development and Neurogenesis
inferredcites →https://doi.org/10.1100/tsw.2006.322openalex-snapshot
Developmental Defects in Trisomy 21 and Mouse Models
inferredcites →https://doi.org/10.1101/gad.855301openalex-snapshot
Requirement for math5 in the development of retinal ganglion cells
inferredcites →https://doi.org/10.1111/j.1365-2788.1996.tb00602.xopenalex-snapshot
Visual acuity and accommodation in infants and young children with Down's syndrome
inferredcites →https://doi.org/10.1111/j.1460-9568.2008.06092.xopenalex-snapshot
The spatio‐temporal and subcellular expression of the candidate Down syndrome gene Mnb/Dyrk1A in the developing mouse brain suggests distinct sequential roles in neuronal development
inferredcites →https://doi.org/10.1111/j.1469-8749.1994.tb11895.xopenalex-snapshot
VISUAL ACUITY IN INFANTS AND CHILDREN WITH DOWN SYNDROME
inferredcites →https://doi.org/10.1126/science.282.5392.1318openalex-snapshot
Regulation of Cell Death Protease Caspase-9 by Phosphorylation
inferredcites →https://doi.org/10.1128/mcb.00394-08openalex-snapshot
Sprouty2-Mediated Inhibition of Fibroblast Growth Factor Signaling Is Modulated by the Protein Kinase DYRK1A
inferredcites →https://doi.org/10.1128/mcb.11.8.4045openalex-snapshot
The Saccharomyces cerevisiae YAK1 gene encodes a protein kinase that is induced by arrest early in the cell cycle.
inferredcites →https://doi.org/10.1128/mcb.22.18.6636-6647.2002openalex-snapshot
Dyrk1A Haploinsufficiency Affects Viability and Causes Developmental Delay and Abnormal Brain Morphology in Mice
inferredcites →https://doi.org/10.1128/mcb.25.23.10543-10555.2005openalex-snapshot
Regulation of Caspase 9 through Phosphorylation by Protein Kinase C Zeta in Response to Hyperosmotic Stress
inferredcites →https://doi.org/10.1158/0008-5472.can-05-1539openalex-snapshot
Mirk/Dyrk1b Mediates Cell Survival in Rhabdomyosarcomas
inferredcites →https://doi.org/10.1158/0008-5472.can-05-3089openalex-snapshot
The Kinase Mirk/Dyrk1B Mediates Cell Survival in Pancreatic Ductal Adenocarcinoma
inferredcites →https://doi.org/10.1159/000472398openalex-snapshot
Molecular Mapping of Twenty-Four Features of Down Syndrome on Chromosome 21
inferredcites →https://doi.org/10.1167/iovs.02-1113openalex-snapshot
Proapoptotic Bcl-2 Family Members, Bax and Bak , Are Essential for Developmental Photoreceptor Apoptosis
inferredcites →https://doi.org/10.1167/iovs.03-0951openalex-snapshot
Spatial Vision Deficits in Infants and Children with Down Syndrome
inferredcites →https://doi.org/10.1167/iovs.04-1123openalex-snapshot
Loss of Circadian Photoentrainment and Abnormal Retinal Electrophysiology in Math5 Mutant Mice
inferredcites →https://doi.org/10.1167/iovs.06-1387openalex-snapshot
The Impact of Optical Factors on Resolution Acuity in Children with Down Syndrome
inferredcites →https://doi.org/10.1242/dev.125.12.2291openalex-snapshot
YakA, a protein kinase required for the transition from growth to development in Dictyostelium
inferredcites →https://doi.org/10.1242/dev.128.13.2497openalex-snapshot
Math5 is required for retinal ganglion cell and optic nerve formation
inferredcites →https://doi.org/10.1242/jcs.00618openalex-snapshot
DYRK1A accumulates in splicing speckles through a novel targeting signal and induces speckle disassembly
inferredcites →https://doi.org/10.1371/journal.pone.0002575openalex-snapshot
Impaired Spatial Learning Strategies and Novel Object Recognition in Mice Haploinsufficient for the Dual Specificity Tyrosine-Regulated Kinase-1A (Dyrk1A)
inferredcites →https://doi.org/10.1387/ijdb.062159mgopenalex-snapshot
Retinal ganglion cells: dying to survive
inferredcites →https://doi.org/10.1523/jneurosci.0903-07.2007openalex-snapshot
Bim Expression Indicates the Pathway to Retinal Cell Death in Development and Degeneration
inferredcites →https://doi.org/10.1523/jneurosci.15-07-04762.1995openalex-snapshot
The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons
inferredcites →https://doi.org/10.1523/jneurosci.16-13-04186.1996openalex-snapshot
Protection of Retinal Ganglion Cells from Natural and Axotomy-Induced Cell Death in Neonatal Transgenic Mice Overexpressing bcl-2
inferredcites →https://doi.org/10.1523/jneurosci.18-21-08936.1998openalex-snapshot
The Major Cell Populations of the Mouse Retina
inferredcites →https://doi.org/10.2174/156652408783769599openalex-snapshot
Regulation of Bcl-2 Family Proteins by Posttranslational Modifications
inferredcites →https://doi.org/10.4049/jimmunol.177.4.2441openalex-snapshot
Identification of PP1α as a Caspase-9 Regulator in IL-2 Deprivation-Induced Apoptosis
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4669820openalex-extracted
Dyrk1a is Required for Craniofacial Development in Xenopus Laevis
inferred← citeshttps://doi.org/10.1002/1873-3468.14723openalex-snapshot
Functions of SRPK , CLK and DYRK kinases in stem cells, development, and human developmental disorders
inferred← citeshttps://doi.org/10.1002/cmdc.201700457openalex-snapshot
A Selective Biligand Inhibitor of CK2 Increases Caspase‐3 Activity in Cancer Cells and Inhibits Platelet Aggregation
inferred← citeshttps://doi.org/10.1002/emmm.201201739openalex-snapshot
The impairment of HCCS leads to MLS syndrome by activating a non‐canonical cell death pathway in the brain and eyes
inferred← citeshttps://doi.org/10.1002/emmm.201302848openalex-snapshot
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21
inferred← citeshttps://doi.org/10.1002/jnr.23007openalex-snapshot
Effect of DYRK1A activity inhibition on development of neuronal progenitors isolated from Ts65Dn mice
inferred← citeshttps://doi.org/10.1007/978-3-030-49844-3_14openalex-snapshot
A Crosstalk Between Dual-Specific Phosphatases and Dual-Specific Protein Kinases Can Be A Potential Therapeutic Target for Anti-cancer Therapy
inferred← citeshttps://doi.org/10.1007/978-3-319-14544-0_19openalex-snapshot
CK2 Inhibitors and the DYRK Family Protein Kinases
inferred← citeshttps://doi.org/10.1007/s00018-009-0123-2openalex-snapshot
Function and regulation of Dyrk1A: towards understanding Down syndrome
inferred← citeshttps://doi.org/10.1007/s00018-020-03626-4openalex-snapshot
DYRK1A: a down syndrome-related dual protein kinase with a versatile role in tumorigenesis
inferred← citeshttps://doi.org/10.1007/s00044-013-0767-1openalex-snapshot
Pharmacophore modeling and 3D-QSAR studies of leucettines as potent Dyrk2 inhibitors
inferred← citeshttps://doi.org/10.1007/s10495-012-0785-3openalex-snapshot
Apoptosis in Down’s syndrome: lessons from studies of human and mouse models
inferred← citeshttps://doi.org/10.1007/s10495-024-01976-zopenalex-snapshot
Exploring caspase functions in mouse models
inferred← citeshttps://doi.org/10.1007/s11010-023-04870-5openalex-snapshot
How does caspases regulation play role in cell decisions? apoptosis and beyond
inferred← citeshttps://doi.org/10.1007/s12035-025-04806-8openalex-snapshot
Unlocking the Therapeutic Potential of the Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A Inhibitors in Alzheimer’s Diseases
inferred← citeshttps://doi.org/10.1016/b978-0-12-803959-5.50015-5openalex-snapshot
Targets and Small Molecules Against Tauopathies. Part 1: From Genes to Soluble, Aggregation-Prone Tau Proteins
inferred← citeshttps://doi.org/10.1016/bs.apcsb.2016.07.001openalex-snapshot
Understanding the Multifaceted Role of Human Down Syndrome Kinase DYRK1A
inferred← citeshttps://doi.org/10.1016/j.abb.2010.12.024openalex-snapshot
Harmine is an ATP-competitive inhibitor for dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A)
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2011.06.023openalex-snapshot
DYRK1A binds to an evolutionarily conserved WD40-repeat protein WDR68 and induces its nuclear translocation
inferred← citeshttps://doi.org/10.1016/j.bbrc.2020.07.130openalex-snapshot
ReN VM spheroids in matrix: A neural progenitor three-dimensional in vitro model reveals DYRK1A inhibitors as potential regulators of radio-sensitivity
inferred← citeshttps://doi.org/10.1016/j.bmcl.2010.04.150openalex-snapshot
Structure–activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors
inferred← citeshttps://doi.org/10.1016/j.cbi.2019.108913openalex-snapshot
Licocoumarone induces BxPC-3 pancreatic adenocarcinoma cell death by inhibiting DYRK1A
inferred← citeshttps://doi.org/10.1016/j.cell.2009.08.021openalex-snapshot
Caspases and Kinases in a Death Grip
inferred← citeshttps://doi.org/10.1016/j.celrep.2018.04.008openalex-snapshot
DYRK1A Kinase Positively Regulates Angiogenic Responses in Endothelial Cells
inferred← citeshttps://doi.org/10.1016/j.chembiol.2024.11.009openalex-snapshot
The efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells
inferred← citeshttps://doi.org/10.1016/j.chemphyslip.2017.10.005openalex-snapshot
Shipment of a photodynamic therapy agent into model membrane and its controlled release: A photophysical approach
inferred← citeshttps://doi.org/10.1016/j.ebiom.2023.104692openalex-snapshot
Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels
inferred← citeshttps://doi.org/10.1016/j.ejphar.2017.03.034openalex-snapshot
A harmine-derived beta-carboline displays anti-cancer effects in vitro by targeting protein synthesis
inferred← citeshttps://doi.org/10.1016/j.gendis.2026.102133openalex-snapshot
Emerging roles of DYRK-mediated DNA damage response in cancer
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2019.07.113openalex-snapshot
Cellular demolition: Proteins as molecular players of programmed cell death
inferred← citeshttps://doi.org/10.1016/j.molcel.2014.12.026openalex-snapshot
Chromatin-wide Profiling of DYRK1A Reveals a Role as a Gene-Specific RNA Polymerase II CTD Kinase
inferred← citeshttps://doi.org/10.1016/j.nbd.2013.08.008openalex-snapshot
Environmental enrichment rescues DYRK1A activity and hippocampal adult neurogenesis in TgDyrk1A
inferred← citeshttps://doi.org/10.1016/j.nbd.2017.12.003openalex-snapshot
DYRK1A-haploinsufficiency in mice causes autistic-like features and febrile seizures
inferred← citeshttps://doi.org/10.1016/j.nbd.2024.106523openalex-snapshot
Shaping down syndrome brain cognitive and molecular changes due to aging using adult animals from the Ts66Yah murine model
inferred← citeshttps://doi.org/10.1016/j.nbd.2026.107379openalex-snapshot
DYRK1A and Parkinson’s disease, facts and hypotheses
inferred← citeshttps://doi.org/10.1016/j.neuint.2011.05.010openalex-snapshot
Tau phosphorylation and neuronal apoptosis induced by the blockade of PP2A preferentially involve GSK3β
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2012.02.001openalex-snapshot
Challenges to congenital genetic disorders with “RNA-targeting” chemical compounds
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2018.09.010openalex-snapshot
DYRK1A and cognition: A lifelong relationship
inferred← citeshttps://doi.org/10.1016/j.phymed.2026.158794openalex-snapshot
Sodium tanshinone IIA sulfonate attenuates pulmonary vascular remodeling by targeting DYRK1A in pulmonary hypertension
inferred← citeshttps://doi.org/10.1016/j.stem.2010.06.021openalex-snapshot
Regulated Segregation of Kinase Dyrk1A during Asymmetric Neural Stem Cell Division Is Critical for EGFR-Mediated Biased Signaling
inferred← citeshttps://doi.org/10.1016/j.tcb.2013.07.006openalex-snapshot
Evading apoptosis in cancer
inferred← citeshttps://doi.org/10.1016/j.tcb.2017.01.003openalex-snapshot
Post-translational Modification of Caspases: The Other Side of Apoptosis Regulation
inferred← citeshttps://doi.org/10.1016/j.ydbio.2024.04.004openalex-snapshot
Dyrk1a is required for craniofacial development in Xenopus laevis.
inferred← citeshttps://doi.org/10.1016/j.ydbio.2025.06.009openalex-snapshot
The role of Goldilocks protein kinase DYRK1A in embryonic development
inferred← citeshttps://doi.org/10.1021/bi9010557openalex-snapshot
Dyrk1A Binds to Multiple Endocytic Proteins Required for Formation of Clathrin-Coated Vesicles
inferred← citeshttps://doi.org/10.1021/jm300542eopenalex-snapshot
Novel Trisubstituted Harmine Derivatives with Original in Vitro Anticancer Activity
inferred← citeshttps://doi.org/10.1038/cddis.2014.253openalex-snapshot
DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson’s disease
inferred← citeshttps://doi.org/10.1038/emboj.2009.253openalex-snapshot
Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase‐2
inferred← citeshttps://doi.org/10.1038/emboj.2011.491openalex-snapshot
Rsk‐mediated phosphorylation and 14‐3‐3ε binding of Apaf‐1 suppresses cytochrome c‐induced apoptosis
inferred← citeshttps://doi.org/10.1038/embor.2011.98openalex-snapshot
p53 downregulates Down syndrome‐associated DYRK1A through miR‐1246
inferred← citeshttps://doi.org/10.1038/mp.2015.5openalex-snapshot
Disruptive de novo mutations of DYRK1A lead to a syndromic form of autism and ID
inferred← citeshttps://doi.org/10.1038/ncomms1090openalex-snapshot
Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A
inferred← citeshttps://doi.org/10.1038/nn.4004openalex-snapshot
Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease
inferred← citeshttps://doi.org/10.1038/nrc2823openalex-snapshot
The regulatory crosstalk between kinases and proteases in cancer
inferred← citeshttps://doi.org/10.1038/nrc3355openalex-snapshot
Tumorigenesis in Down's syndrome: big lessons from a small chromosome
inferred← citeshttps://doi.org/10.1038/oncsis.2014.17openalex-snapshot
Inhibitors of enhancer of zeste homolog 2 (EZH2) activate tumor-suppressor microRNAs in human cancer cells
inferred← citeshttps://doi.org/10.1038/s41598-020-66750-yopenalex-snapshot
A novel de novo heterozygous DYRK1A mutation causes complete loss of DYRK1A function and developmental delay
inferred← citeshttps://doi.org/10.1038/s41598-022-06984-0openalex-snapshot
A reassessment of Jackson’s checklist and identification of two Down syndrome sub-phenotypes
inferred← citeshttps://doi.org/10.1042/bcj20210399openalex-snapshot
Kinases leave their mark on caspase substrates
inferred← citeshttps://doi.org/10.1073/pnas.1704143114openalex-snapshot
Prenatal neurogenesis induction therapy normalizes brain structure and function in Down syndrome mice
inferred← citeshttps://doi.org/10.1074/jbc.m110.102574openalex-snapshot
DYRK1A and DYRK3 Promote Cell Survival through Phosphorylation and Activation of SIRT1
inferred← citeshttps://doi.org/10.1074/jbc.m110.147520openalex-snapshot
Dyrk1A Phosphorylates p53 and Inhibits Proliferation of Embryonic Neuronal Cells
inferred← citeshttps://doi.org/10.1074/jbc.m110.174540openalex-snapshot
REST Regulates DYRK1A Transcription in a Negative Feedback Loop
inferred← citeshttps://doi.org/10.1074/jbc.m117.811976openalex-snapshot
Active site–adjacent phosphorylation at Tyr-397 by c-Abl kinase inactivates caspase-9
inferred← citeshttps://doi.org/10.1080/13816810.2020.1814349openalex-snapshot
Ocular findings of albinism in DYRK1A-related intellectual disability syndrome
inferred← citeshttps://doi.org/10.1080/13816810.2025.2503388openalex-snapshot
DYRK1A syndrome presenting with a familial exudative vitreoretinopathy (FEVR)-like retinovascular phenotype
inferred← citeshttps://doi.org/10.1080/13816810.2026.2635639openalex-snapshot
Ocular manifestations in DYRK1A mutation: a five-case series from South Korea
inferred← citeshttps://doi.org/10.1093/hmg/ddt125openalex-snapshot
Triplication of DYRK1A causes retinal structural and functional alterations in Down syndrome
inferred← citeshttps://doi.org/10.1093/nar/gkae574openalex-snapshot
Nuclear F-actin assembly on damaged chromatin is regulated by DYRK1A and Spir1 phosphorylation
inferred← citeshttps://doi.org/10.1093/plcell/koae271openalex-snapshot
The DYRKP1 kinase regulates cell wall degradation in Chlamydomonas by inducing matrix metalloproteinase expression
inferred← citeshttps://doi.org/10.1096/fj.10-165837openalex-snapshot
DYRK family of protein kinases: evolutionary relationships, biochemical properties, and functional roles
inferred← citeshttps://doi.org/10.1101/2023.09.18.558244openalex-snapshot
Congenital heart defects in Down syndrome are caused by increased dosage of DYRK1A
inferred← citeshttps://doi.org/10.1101/2024.01.02.573811openalex-snapshot
Cognitive and molecular characterization of the Ts66Yah murine model of Down syndrome: deepening on hippocampal changes associated with genotype and aging
inferred← citeshttps://doi.org/10.1101/cshperspect.a008672openalex-snapshot
Cellular Mechanisms Controlling Caspase Activation and Function
inferred← citeshttps://doi.org/10.1101/gad.297077.117openalex-snapshot
Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA
inferred← citeshttps://doi.org/10.1111/imb.12671openalex-snapshot
Caste‐specific gene expression underlying the differential adult brain development in the honeybee Apis mellifera
inferred← citeshttps://doi.org/10.1111/imb.12955openalex-snapshot
Minibrain plays a role in the adult brain development of honeybee ( Apis mellifera ) workers
inferred← citeshttps://doi.org/10.1111/j.1365-2141.2011.08985.xopenalex-snapshot
Amplified segment in the ‘Down Syndrome critical region’ on HSA21 shared between Down syndrome and euploid AML‐M0 excludes RUNX1, ERG and ETS2
inferred← citeshttps://doi.org/10.1111/j.1399-0004.2010.01544.xopenalex-snapshot
Intragenic deletion in DYRK1A leads to mental retardation and primary microcephaly
inferred← citeshttps://doi.org/10.1111/j.1742-4658.2009.07330.xopenalex-snapshot
Apoptosis and autophagy: Regulation of caspase‐9 by phosphorylation
inferred← citeshttps://doi.org/10.1111/j.1742-4658.2009.07346.xopenalex-snapshot
Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation
inferred← citeshttps://doi.org/10.1111/j.1742-4658.2010.07954.xopenalex-snapshot
MNB/DYRK1A as a multiple regulator of neuronal development
inferred← citeshttps://doi.org/10.1111/j.1742-4658.2010.07956.xopenalex-snapshot
Activation, regulation, and inhibition of DYRK1A
inferred← citeshttps://doi.org/10.1111/jnc.16142openalex-snapshot
Inhalation of hydrogen gas mitigates sevoflurane‐induced neuronal apoptosis in the neonatal cortex and is associated with changes in protein phosphorylation
inferred← citeshttps://doi.org/10.1126/scisignal.2000579openalex-snapshot
Characterization of a Domain That Transiently Converts Class 2 DYRKs into Intramolecular Tyrosine Kinases
inferred← citeshttps://doi.org/10.1126/scitranslmed.add6883openalex-snapshot
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome
inferred← citeshttps://doi.org/10.1128/jvi.01239-23openalex-snapshot
DYRK1A is a multifunctional host factor that regulates coronavirus replication in a kinase-independent manner
inferred← citeshttps://doi.org/10.1134/s0006297915060152openalex-snapshot
Expression of neuronal and signaling proteins in penumbra around a photothrombotic infarction core in rat cerebral cortex
inferred← citeshttps://doi.org/10.1139/o11-080openalex-snapshot
The C-terminal region of E1A: a molecular tool for cellular cartography
inferred← citeshttps://doi.org/10.11606/t.41.2016.tde-05052016-112830openalex-snapshot
Caracterização de rearranjos cromossômicos citogeneticamente equilibrados associados a quadros clínicos
inferred← citeshttps://doi.org/10.1172/jci63623openalex-snapshot
Inhibition of DYRK1A destabilizes EGFR and reduces EGFR-dependent glioblastoma growth
inferred← citeshttps://doi.org/10.1210/en.2014-1329openalex-snapshot
DYRK1A BAC Transgenic Mouse: A New Model of Thyroid Dysgenesis in Down Syndrome
inferred← citeshttps://doi.org/10.1242/dev.066167openalex-snapshot
Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling
inferred← citeshttps://doi.org/10.1371/journal.pone.0007540openalex-snapshot
DYRK1A, a Novel Determinant of the Methionine-Homocysteine Cycle in Different Mouse Models Overexpressing this Down-Syndrome-Associated Kinase
inferred← citeshttps://doi.org/10.1371/journal.pone.0029702openalex-snapshot
Deep Evolutionary Conservation of an Intramolecular Protein Kinase Activation Mechanism
inferred← citeshttps://doi.org/10.1371/journal.pone.0076775openalex-snapshot
Drosophila Dyrk2 Plays a Role in the Development of the Visual System
inferred← citeshttps://doi.org/10.1371/journal.pone.0106572openalex-snapshot
Overexpression of Dyrk1A Is Implicated in Several Cognitive, Electrophysiological and Neuromorphological Alterations Found in a Mouse Model of Down Syndrome
inferred← citeshttps://doi.org/10.1371/journal.pone.0118003openalex-snapshot
Discovery of New Candidate Genes Related to Brain Development Using Protein Interaction Information
inferred← citeshttps://doi.org/10.1371/journal.pone.0159954openalex-snapshot
Low Expression of DYRK2 (Dual Specificity Tyrosine Phosphorylation Regulated Kinase 2) Correlates with Poor Prognosis in Colorectal Cancer
inferred← citeshttps://doi.org/10.14233/ajchem.2023.30477openalex-snapshot
Anticancer and Antimicrobial Screening of Novel Pyrazolo[2,3-c]pyridopyridazine Analogues: Synthesis, Spectral Characterization, Molecular Docking and Dynamics Studies
inferred← citeshttps://doi.org/10.1523/jneurosci.6015-10.2011openalex-snapshot
The Down Syndrome Critical Region Regulates Retinogeniculate Refinement
inferred← citeshttps://doi.org/10.15252/embr.201643803openalex-snapshot
The phosphorylation status of T522 modulates tissue‐specific functions of SIRT1 in energy metabolism in mice
inferred← citeshttps://doi.org/10.18632/oncotarget.15098openalex-snapshot
Caspase-9: structure, mechanisms and clinical application
inferred← citeshttps://doi.org/10.2174/138955712804586639openalex-snapshot
DYRK1A Kinase Inhibitors with Emphasis on Cancer
inferred← citeshttps://doi.org/10.2174/1568026623666230203141543openalex-snapshot
Acridine: A Scaffold for the Development of Drugs for Alzheimer's Disease
inferred← citeshttps://doi.org/10.2174/1570159x20666220327222921openalex-snapshot
Inhibition of Caspase 3 and Caspase 9 Mediated Apoptosis: A Multimodal Therapeutic Target in Traumatic Brain Injury
inferred← citeshttps://doi.org/10.3389/fcell.2022.1075751openalex-snapshot
Making the head: Caspases in life and death
inferred← citeshttps://doi.org/10.3389/fcell.2022.840023openalex-snapshot
Non-Canonical Roles of Apoptotic Caspases in the Nervous System
inferred← citeshttps://doi.org/10.3389/fcell.2026.1963992openalex-snapshot
DYRK1A – a gene dose paradox
inferred← citeshttps://doi.org/10.3389/fgene.2023.1290949openalex-snapshot
Identification of two novel and one rare mutation in DYRK1A and prenatal diagnoses in three Chinese families with intellectual Disability-7
inferred← citeshttps://doi.org/10.3389/fmicb.2021.658721openalex-snapshot
Interplay Between CMGC Kinases Targeting SR Proteins and Viral Replication: Splicing and Beyond
inferred← citeshttps://doi.org/10.3389/fnbeh.2016.00104openalex-snapshot
DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome
inferred← citeshttps://doi.org/10.3390/genes12020234openalex-snapshot
Ocular Phenotype Associated with DYRK1A Variants
inferred← citeshttps://doi.org/10.3390/genes12111833openalex-snapshot
Dyrk1a from Gene Function in Development and Physiology to Dosage Correction across Life Span in Down Syndrome
inferred← citeshttps://doi.org/10.3390/ijms20092098openalex-snapshot
Precision Revisited: Targeting Microcephaly Kinases in Brain Tumors
inferred← citeshttps://doi.org/10.3390/ijms23169355openalex-snapshot
The Omnipresence of DYRK1A in Human Diseases
inferred← citeshttps://doi.org/10.3390/ijms27083456openalex-snapshot
Targeting DYRKs in Cardiovascular Diseases: From Biological Mechanisms to Therapeutic Translation
inferred← citeshttps://doi.org/10.3390/molecules24224090openalex-snapshot
[b]-Annulated Halogen-Substituted Indoles as Potential DYRK1A Inhibitors
inferred← citeshttps://doi.org/10.4161/23723548.2014.970048openalex-snapshot
DYRK1A: the double-edged kinase as a protagonist in cell growth and tumorigenesis
inferred← citeshttps://doi.org/10.4161/cc.20809openalex-snapshot
MiR-1246: A new link of the p53 family with cancer and Down syndrome
inferred← citeshttps://doi.org/10.4251/wjgo.v16.i4.1453openalex-snapshot
MicroRNA-298 determines the radio-resistance of colorectal cancer cells by directly targeting human dual-specificity tyrosine(Y)-regulated kinase 1A
inferred← citeshttps://doi.org/10.53846/goediss-9329openalex-snapshot
Modifications in AP2 and clathrin-mediated endocytosis as a mechanism of synaptic plasticity
inferred← citeshttps://doi.org/10.5772/intechopen.70039openalex-snapshot
Biological Consequences of Priming Phosphorylation in Cancer Development
inferred← citeshttps://doi.org/10.64898/2026.03.15.710015openalex-snapshot
Dyrk1a gene dosage controls bipolar cell development and retinal connectivity
inferred← citeshttps://doi.org/10.64898/2026.04.18.719349openalex-snapshot
Plagl2 unlocks the latent regenerative potential of Müller glia in the adult mouse retina
inferred← citeshttps://doi.org/10.70675/37ec63a1z9652z4b2czbff5zc55c5d157bbeopenalex-snapshot
Correction des déficits cognitifs chez des modèles murins de trisomie 21 par un inhibiteur de la kinase DYRK1A : étude pharmacologique et mécanistique
inferred← citeshttps://doi.org/10.70675/57e0f3d3z704dz4113z974bz4e76939b1c8copenalex-snapshot
Rôle de XDSCR6 et de ses partenaires au cours du développement embryonnaire précoce de Xenopus laevis
inferred← citeshttps://doi.org/10.70675/6f03bc10zd5a4z414eza3c0z67e0b10f79f6openalex-snapshot
Synthèse et évaluation biologique d’imidazo[1,2-b]pyridazines et de purines inhibitrices de protéines kinases
Editorial review for independent work. ICSAC — the Institute for Complexity
Science and Advanced Computing — runs a structured editorial panel for researchers
publishing outside journals, and publishes on CiteStamp rails. Submission is free
and goes through ORCID: icsacinstitute.org/submit.