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The cellular and molecular mechanisms of vertebrate lens development
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/bies.20009openalex-snapshot
Anterior eye development and ocular mesenchyme: new insights from mouse models and human diseases
inferredcites →https://doi.org/10.1002/dvdy.20128openalex-snapshot
Raldh2 expression in optic vesicle generates a retinoic acid signal needed for invagination of retina during optic cup formation
inferredcites →https://doi.org/10.1002/dvdy.21445openalex-snapshot
Cell autonomous roles for AP‐2α in lens vesicle separation and maintenance of the lens epithelial cell phenotype
inferredcites →https://doi.org/10.1002/dvdy.21924openalex-snapshot
Pitx3 controls multiple aspects of lens development
inferredcites →https://doi.org/10.1002/dvdy.22035openalex-snapshot
Transcription factor GATA‐3 is essential for lens development
inferredcites →https://doi.org/10.1002/dvdy.22036openalex-snapshot
Cell‐autonomous requirements for Dlg‐1 for lens epithelial cell structure and fiber cell morphogenesis
inferredcites →https://doi.org/10.1002/dvdy.22056openalex-snapshot
Targeted deletion of Dicer disrupts lens morphogenesis, corneal epithelium stratification, and whole eye development
inferredcites →https://doi.org/10.1002/dvdy.23739openalex-snapshot
Requirements for Jag1‐Rbpj mediated Notch signaling during early mouse lens development
inferredcites →https://doi.org/10.1002/dvdy.23935openalex-snapshot
Distinct roles for N‐Cadherin linked c‐Src and fyn kinases in lens development
inferredcites →https://doi.org/10.1002/dvdy.24077openalex-snapshot
Expression of the de novo DNA methyltransferases (dnmt3 – dnmt8) during zebrafish lens development
inferredcites →https://doi.org/10.1002/dvdy.24141openalex-snapshot
AP‐2α is required after lens vesicle formation to maintain lens integrity
inferredcites →https://doi.org/10.1002/dvg.20277openalex-snapshot
Abnormal lens morphogenesis and ectopic lens formation in the absence of β‐catenin function
inferredcites →https://doi.org/10.1002/stem.758openalex-snapshot
Fibroblast Growth Factor Regulates Human Neuroectoderm Specification Through ERK1/2-PARP-1 Pathway
inferredcites →https://doi.org/10.1006/dbio.1998.9153openalex-snapshot
BMP7 Acts in Murine Lens Placode Development
inferredcites →https://doi.org/10.1006/dbio.2000.9652openalex-snapshot
Altered Retinoid Signaling in the Heads of Small eye Mouse Embryos
inferredcites →https://doi.org/10.1006/geno.2001.6505openalex-snapshot
Identification of Differentially Expressed Nucleolar TGF-β1 Target (DENTT) in Human Lung Cancer Cells That Is a New Member of the TSPY/SET/NAP-1 Superfamily
inferredcites →https://doi.org/10.1007/s00018-013-1335-zopenalex-snapshot
Non-coding RNAs in the development of sensory organs and related diseases
inferredcites →https://doi.org/10.1007/s00335-013-9478-7openalex-snapshot
Crybb2 coding for βB2-crystallin affects sensorimotor gating and hippocampal function
inferredcites →https://doi.org/10.1016/0168-9525(92)90280-hopenalex-snapshot
Embryonic lens induction: shedding light on vertebrate tissue determination
inferredcites →https://doi.org/10.1016/0896-6273(95)90262-7openalex-snapshot
Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres
inferredcites →https://doi.org/10.1016/j.ajhg.2011.05.008openalex-snapshot
Mutations in FYCO1 Cause Autosomal-Recessive Congenital Cataracts
inferredcites →https://doi.org/10.1016/j.ajhg.2011.09.014openalex-snapshot
Mutation Altering the miR-184 Seed Region Causes Familial Keratoconus with Cataract
inferredcites →https://doi.org/10.1016/j.ajpath.2012.02.017openalex-snapshot
Loss of Msx2 Function Down-Regulates the FoxE3 Expression and Results in Anterior Segment Dysgenesis Resembling Peters Anomaly
inferredcites →https://doi.org/10.1016/j.biocel.2010.09.012openalex-snapshot
The lens epithelium in ocular health and disease
inferredcites →https://doi.org/10.1016/j.cell.2006.09.045openalex-snapshot
Deletion of DDB1 in Mouse Brain and Lens Leads to p53-Dependent Elimination of Proliferating Cells
inferredcites →https://doi.org/10.1016/j.celrep.2013.10.048openalex-snapshot
Specification of Functional Cranial Placode Derivatives from Human Pluripotent Stem Cells
inferredcites →https://doi.org/10.1016/j.devcel.2006.08.009openalex-snapshot
Lens Specification Is the Ground State of All Sensory Placodes, from which FGF Promotes Olfactory Identity
inferredcites →https://doi.org/10.1016/j.devcel.2007.04.020openalex-snapshot
Time of Exposure to BMP Signals Plays a Key Role in the Specification of the Olfactory and Lens Placodes Ex Vivo
inferredcites →https://doi.org/10.1016/j.devcel.2013.04.005openalex-snapshot
Chromatin Regulation by BAF170 Controls Cerebral Cortical Size and Thickness
inferredcites →https://doi.org/10.1016/j.devcel.2013.07.001openalex-snapshot
Neuropeptides: Developmental Signals in Placode Progenitor Formation
inferredcites →https://doi.org/10.1016/j.dnarep.2006.05.004openalex-snapshot
A novel function of DNA repair molecule Nbs1 in terminal differentiation of the lens fibre cells and cataractogenesis
inferredcites →https://doi.org/10.1016/j.ejmg.2014.05.002openalex-snapshot
The genetic architecture of microphthalmia, anophthalmia and coloboma
inferredcites →https://doi.org/10.1016/j.exer.2008.03.004openalex-snapshot
Anterior segment dysgenesis in the eyes of mice deficient for the high-mobility-group transcription factor Sox11
inferredcites →https://doi.org/10.1016/j.exer.2008.08.017openalex-snapshot
On the mechanism of organelle degradation in the vertebrate lens
inferredcites →https://doi.org/10.1016/j.exer.2009.04.012openalex-snapshot
Retinoic acid signaling in mammalian eye development
inferredcites →https://doi.org/10.1016/j.exer.2011.03.012openalex-snapshot
The fate of dividing cells during lens morphogenesis, differentiation and growth
inferredcites →https://doi.org/10.1016/j.exer.2013.08.017openalex-snapshot
Autophagy and mitophagy participate in ocular lens organelle degradation
inferredcites →https://doi.org/10.1016/j.mod.2013.09.005openalex-snapshot
Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development
inferredcites →https://doi.org/10.1016/j.modgep.2005.04.010openalex-snapshot
Pax6-dependence of Six3, Eya1 and Dach1 expression during lens and nasal placode induction
inferredcites →https://doi.org/10.1016/j.neuron.2010.09.030openalex-snapshot
The Transcription Factor Pax6 Regulates Survival of Dopaminergic Olfactory Bulb Neurons via Crystallin αA
inferredcites →https://doi.org/10.1016/j.preteyeres.2007.07.002openalex-snapshot
Genetic and epigenetic mechanisms of gene regulation during lens development
inferredcites →https://doi.org/10.1016/j.preteyeres.2012.04.002openalex-snapshot
Pax6: A multi-level regulator of ocular development
inferredcites →https://doi.org/10.1016/j.semcdb.2006.10.004openalex-snapshot
Cell cycle regulation in the developing lens
inferredcites →https://doi.org/10.1016/j.semcdb.2006.10.011openalex-snapshot
The role of the lens actin cytoskeleton in fiber cell elongation and differentiation
inferredcites →https://doi.org/10.1016/j.stem.2011.09.001openalex-snapshot
Sox2+ Adult Stem and Progenitor Cells Are Important for Tissue Regeneration and Survival of Mice
inferredcites →https://doi.org/10.1016/j.stem.2013.07.002openalex-snapshot
The BAF Complex Interacts with Pax6 in Adult Neural Progenitors to Establish a Neurogenic Cross-Regulatory Transcriptional Network
inferredcites →https://doi.org/10.1016/j.tibs.2014.02.003openalex-snapshot
FOXO transcription factors: key regulators of cellular quality control
inferredcites →https://doi.org/10.1016/j.ydbio.2004.04.010openalex-snapshot
Segregation of lens and olfactory precursors from a common territory: cell sorting and reciprocity of Dlx5 and Pax6 expression
inferredcites →https://doi.org/10.1016/j.ydbio.2004.07.016openalex-snapshot
Requirement for Mab21l2 during development of murine retina and ventral body wall
inferredcites →https://doi.org/10.1016/j.ydbio.2005.01.020openalex-snapshot
Growth factor regulation of lens development
inferredcites →https://doi.org/10.1016/j.ydbio.2005.06.010openalex-snapshot
Multiple requirements for Hes1 during early eye formation
inferredcites →https://doi.org/10.1016/j.ydbio.2005.07.019openalex-snapshot
The duality of β-catenin function: A requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm
inferredcites →https://doi.org/10.1016/j.ydbio.2005.08.015openalex-snapshot
Absence of non-specific effects of RNA interference triggered by long double-stranded RNA in mouse oocytes
inferredcites →https://doi.org/10.1016/j.ydbio.2006.03.056openalex-snapshot
Actin filament organization regulates the induction of lens cell differentiation and survival
inferredcites →https://doi.org/10.1016/j.ydbio.2006.09.021openalex-snapshot
Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage
inferredcites →https://doi.org/10.1016/j.ydbio.2006.10.047openalex-snapshot
Sox2 and Pou2f1 interact to control lens and olfactory placode development
inferredcites →https://doi.org/10.1016/j.ydbio.2008.03.028openalex-snapshot
Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation
inferredcites →https://doi.org/10.1016/j.ydbio.2008.06.002openalex-snapshot
Notch signaling regulates growth and differentiation in the mammalian lens
inferredcites →https://doi.org/10.1016/j.ydbio.2008.07.002openalex-snapshot
Differential requirement for β-catenin in epithelial and fiber cells during lens development
inferredcites →https://doi.org/10.1016/j.ydbio.2008.09.002openalex-snapshot
Wnt signaling is required for organization of the lens fiber cell cytoskeleton and development of lens three-dimensional architecture
inferredcites →https://doi.org/10.1016/j.ydbio.2008.09.003openalex-snapshot
Essential role of BMPs in FGF-induced secondary lens fiber differentiation
inferredcites →https://doi.org/10.1016/j.ydbio.2008.10.011openalex-snapshot
Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival
inferredcites →https://doi.org/10.1016/j.ydbio.2009.01.015openalex-snapshot
Jagged 1 is necessary for normal mouse lens formation
inferredcites →https://doi.org/10.1016/j.ydbio.2009.05.572openalex-snapshot
Molecular and tissue interactions governing induction of cranial ectodermal placodes
inferredcites →https://doi.org/10.1016/j.ydbio.2009.08.027openalex-snapshot
The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation
inferredcites →https://doi.org/10.1016/j.ydbio.2009.09.009openalex-snapshot
Apical constriction: A cell shape change that can drive morphogenesis
inferredcites →https://doi.org/10.1016/j.ydbio.2009.10.010openalex-snapshot
A cell polarity protein aPKCλ is required for eye lens formation and growth
inferredcites →https://doi.org/10.1016/j.ydbio.2009.11.033openalex-snapshot
Secreted frizzled-related protein disrupts PCP in eye lens fiber cells that have polarised primary cilia
inferredcites →https://doi.org/10.1016/j.ydbio.2010.11.009openalex-snapshot
Uhrf1 and Dnmt1 are required for development and maintenance of the zebrafish lens
inferredcites →https://doi.org/10.1016/j.ydbio.2011.01.001openalex-snapshot
The function of FGF signaling in the lens placode
inferredcites →https://doi.org/10.1016/j.ydbio.2011.04.007openalex-snapshot
Genetic epistasis between heparan sulfate and FGF–Ras signaling controls lens development
inferredcites →https://doi.org/10.1016/j.ydbio.2011.04.008openalex-snapshot
The mechanism of lens placode formation: A case of matrix-mediated morphogenesis
inferredcites →https://doi.org/10.1016/j.ydbio.2011.09.004openalex-snapshot
Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival
inferredcites →https://doi.org/10.1016/j.ydbio.2011.11.011openalex-snapshot
Conditional ablation of the Notch2 receptor in the ocular lens
inferredcites →https://doi.org/10.1016/j.ydbio.2012.04.025openalex-snapshot
Mutual repression between Gbx2 and Otx2 in sensory placodes reveals a general mechanism for ectodermal patterning
inferredcites →https://doi.org/10.1016/j.ydbio.2012.06.028openalex-snapshot
The peripheral sensory nervous system in the vertebrate head: A gene regulatory perspective
inferredcites →https://doi.org/10.1016/j.ydbio.2013.04.023openalex-snapshot
Differential BMP signaling controls formation and differentiation of multipotent preplacodal ectoderm progenitors from human embryonic stem cells
inferredcites →https://doi.org/10.1016/j.ydbio.2013.09.027openalex-snapshot
Scrib is required for epithelial cell identity and prevents epithelial to mesenchymal transition in the mouse
inferredcites →https://doi.org/10.1016/j.ydbio.2013.10.030openalex-snapshot
Interactions between lens epithelial and fiber cells reveal an intrinsic self-assembly mechanism
inferredcites →https://doi.org/10.1016/j.ydbio.2013.11.027openalex-snapshot
Setting appropriate boundaries: Fate, patterning and competence at the neural plate border
inferredcites →https://doi.org/10.1016/j.ydbio.2013.12.037openalex-snapshot
Dual function of Yap in the regulation of lens progenitor cells and cellular polarity
inferredcites →https://doi.org/10.1016/j.yexcr.2013.08.002openalex-snapshot
Signaling pathways regulating ectodermal cell fate choices
inferredcites →https://doi.org/10.1016/s0012-1606(03)00058-7openalex-snapshot
Pax6 autoregulation mediated by direct interaction of Pax6 protein with the head surface ectoderm-specific enhancer of the mouse Pax6 gene
inferredcites →https://doi.org/10.1016/s0014-4835(80)80011-xopenalex-snapshot
Cytoplasmic processes interconnect lens placode and optic vesicle during eye morphogenesis
inferredcites →https://doi.org/10.1016/s0014-5793(03)01083-4openalex-snapshot
Aquaporin water channels: molecular mechanisms for human diseases1
inferredcites →https://doi.org/10.1016/s0166-2236(97)01082-5openalex-snapshot
Current views on eye development
inferredcites →https://doi.org/10.1016/s0925-4773(01)00645-1openalex-snapshot
Prox1 is differentially localized during lens development
inferredcites →https://doi.org/10.1016/s0925-4773(02)00260-5openalex-snapshot
Pax6 heterozygous eyes show defects in chamber angle differentiation that are associated with a wide spectrum of other anterior eye segment abnormalities
inferredcites →https://doi.org/10.1038/26500openalex-snapshot
A function for lipoxygenase in programmed organelle degradation
inferredcites →https://doi.org/10.1038/371072a0openalex-snapshot
p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
inferredcites →https://doi.org/10.1038/42475openalex-snapshot
The Rx homeobox gene is essential for vertebrate eye development
inferredcites →https://doi.org/10.1038/6844openalex-snapshot
Prox1 function is crucial for mouse lens-fibre elongation
inferredcites →https://doi.org/10.1038/hdy.2010.16openalex-snapshot
Epigenetic regulatory mechanisms in vertebrate eye development and disease
inferredcites →https://doi.org/10.1038/nature01895openalex-snapshot
Nuclear cataract caused by a lack of DNA degradation in the mouse eye lens
inferredcites →https://doi.org/10.1038/nature03964openalex-snapshot
Phosphatidylserine-dependent engulfment by macrophages of nuclei from erythroid precursor cells
inferredcites →https://doi.org/10.1038/nature05935openalex-snapshot
Protective and therapeutic role for αB-crystallin in autoimmune demyelination
inferredcites →https://doi.org/10.1038/nature07006openalex-snapshot
Essential role for Nix in autophagic maturation of erythroid cells
inferredcites →https://doi.org/10.1038/nature07730openalex-snapshot
ChIP-seq accurately predicts tissue-specific activity of enhancers
inferredcites →https://doi.org/10.1038/nature11748openalex-snapshot
Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin
inferredcites →https://doi.org/10.1038/ng0296-212openalex-snapshot
Mutations in the founder of the MIP gene family underlie cataract development in the mouse
inferredcites →https://doi.org/10.1038/ng1321openalex-snapshot
Oculofaciocardiodental and Lenz microphthalmia syndromes result from distinct classes of mutations in BCOR
inferredcites →https://doi.org/10.1038/nmeth.1945openalex-snapshot
Direct visualization of specifically modified extracellular glycans in living animals
inferredcites →https://doi.org/10.1038/nrc2780openalex-snapshot
Fibroblast growth factor signalling: from development to cancer
inferredcites →https://doi.org/10.1038/nrm3528openalex-snapshot
Exploring mechanisms of FGF signalling through the lens of structural biology
inferredcites →https://doi.org/10.1038/nrn786openalex-snapshot
Neural induction, the default model and embryonic stem cells
inferredcites →https://doi.org/10.1038/sj.cdd.4400351openalex-snapshot
Analysis of nuclear degradation during lens cell differentiation
inferredcites →https://doi.org/10.1038/sj.emboj.7600038openalex-snapshot
Hematopoietic, angiogenic and eye defects in Meis1 mutant animals
inferredcites →https://doi.org/10.1038/sj.emboj.7600435openalex-snapshot
HSF4 is required for normal cell growth and differentiation during mouse lens development
inferredcites →https://doi.org/10.1038/sj.emboj.7601114openalex-snapshot
Regulation of αA‐crystallin via Pax6, c‐Maf, CREB and a broad domain of lens‐specific chromatin
inferredcites →https://doi.org/10.1038/sj.emboj.7601398openalex-snapshot
Six3 activation of Pax6 expression is essential for mammalian lens induction and specification
inferredcites →https://doi.org/10.1073/pnas.0407577101openalex-snapshot
Tyrosine phosphorylation sites on FRS2α responsible for Shp2 recruitment are critical for induction of lens and retina
inferredcites →https://doi.org/10.1073/pnas.0808987105openalex-snapshot
Loss of ephrin-A5 function disrupts lens fiber cell packing and leads to cataract
inferredcites →https://doi.org/10.1073/pnas.0914785107openalex-snapshot
miR-204 is required for lens and retinal development via Meis2 targeting
inferredcites →https://doi.org/10.1073/pnas.1108993108openalex-snapshot
Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia
inferredcites →https://doi.org/10.1073/pnas.1302934110openalex-snapshot
Translation initiation factor eIF3h targets specific transcripts to polysomes during embryogenesis
inferredcites →https://doi.org/10.1073/pnas.1315034111openalex-snapshot
Sumoylation differentially regulates Sp1 to control cell differentiation
inferredcites →https://doi.org/10.1073/pnas.132195699openalex-snapshot
Mutually regulated expression of Pax6 and Six3 and its implications for the Pax6 haploinsufficient lens phenotype
inferredcites →https://doi.org/10.1073/pnas.82.23.7815openalex-snapshot
Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine alpha A-crystallin promoter in transgenic mice.
inferredcites →https://doi.org/10.1073/pnas.92.13.6142openalex-snapshot
An apoptotic defect in lens differentiation caused by human p53 is rescued by a mutant allele.
inferredcites →https://doi.org/10.1073/pnas.94.3.884openalex-snapshot
Targeted disruption of the mouse αA-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein αB-crystallin
inferredcites →https://doi.org/10.1073/pnas.96.25.14378openalex-snapshot
Pax6 is essential for establishing ventral-dorsal cell boundaries in pituitary gland development
inferredcites →https://doi.org/10.1073/pnas.96.7.3781openalex-snapshot
Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development
inferredcites →https://doi.org/10.1074/jbc.274.21.15115openalex-snapshot
Phosphorylation of the Transactivation Domain of Pax6 by Extracellular Signal-regulated Kinase and p38 Mitogen-activated Protein Kinase
inferredcites →https://doi.org/10.1074/jbc.274.27.19254openalex-snapshot
Regulation of Lens Fiber Cell Differentiation by Transcription Factor c-Maf
inferredcites →https://doi.org/10.1074/jbc.m009723200openalex-snapshot
Caspase Remodeling of the Spectrin Membrane Skeleton during Lens Development and Aging
inferredcites →https://doi.org/10.1074/jbc.m107995200openalex-snapshot
Defects of the Heart, Eye, and Megakaryocytes in Peroxisome Proliferator Activator Receptor-binding Protein (PBP) Null Embryos Implicate GATA Family of Transcription Factors
inferredcites →https://doi.org/10.1074/jbc.m109.073676openalex-snapshot
Dnmt3 and G9a Cooperate for Tissue-specific Development in Zebrafish
inferredcites →https://doi.org/10.1074/jbc.m110.148627openalex-snapshot
The Common Modification in αA-Crystallin in the Lens, N101D, Is Associated with Increased Opacity in a Mouse Model
inferredcites →https://doi.org/10.1074/jbc.m111.264580openalex-snapshot
The Orchestration of Mammalian Tissue Morphogenesis through a Series of Coherent Feed-forward Loops
inferredcites →https://doi.org/10.1074/jbc.m112.341586openalex-snapshot
Insulin-like Growth Factor Receptor-1 and Nuclear Factor κB Are Crucial Survival Signals That Regulate Caspase-3-mediated Lens Epithelial Cell Differentiation Initiation
inferredcites →https://doi.org/10.1074/jbc.m113.515254openalex-snapshot
α6 Integrin Transactivates Insulin-like Growth Factor Receptor-1 (IGF-1R) to Regulate Caspase-3-mediated Lens Epithelial Cell Differentiation Initiation
inferredcites →https://doi.org/10.1074/jbc.m114.549584openalex-snapshot
Crystallin-αB Regulates Skeletal Muscle Homeostasis via Modulation of Argonaute2 Activity
inferredcites →https://doi.org/10.1074/jbc.m313683200openalex-snapshot
Temporal Regulation of VEID-7-amino-4-trifluoromethylcoumarin Cleavage Activity and Caspase-6 Correlates with Organelle Loss during Lens Development
inferredcites →https://doi.org/10.1074/jbc.m403473200openalex-snapshot
Lens Major Intrinsic Protein (MIP)/Aquaporin 0 Expression in Rat Lens Epithelia Explants Requires Fibroblast Growth Factor-induced ERK and JNK Signaling
inferredcites →https://doi.org/10.1074/jbc.m414270200openalex-snapshot
The Canonical Intrinsic Mitochondrial Death Pathway Has a Non-apoptotic Role in Signaling Lens Cell Differentiation
inferredcites →https://doi.org/10.1074/jbc.m504007200openalex-snapshot
Role of the Executioner Caspases during Lens Development
inferredcites →https://doi.org/10.1074/jbc.m611476200openalex-snapshot
Protein Phosphatase-1 Modulates the Function of Pax-6, a Transcription Factor Controlling Brain and Eye Development
inferredcites →https://doi.org/10.1074/jbc.m804629200openalex-snapshot
Analysis of HSF4 Binding Regions Reveals Its Necessity for Gene Regulation during Development and Heat Shock Response in Mouse Lenses
inferredcites →https://doi.org/10.1083/jcb.137.1.37openalex-snapshot
Chromatin Degradation in Differentiating Fiber Cells of the Eye Lens
inferredcites →https://doi.org/10.1091/mbc.e09-12-1031openalex-snapshot
Lens Fiber Cell Differentiation and Denucleation Are Disrupted through Expression of the N-Terminal Nuclear Receptor Box ofNcoa6and Result in p53-dependent and p53-independent Apoptosis
inferredcites →https://doi.org/10.1091/mbc.e12-01-0075openalex-snapshot
A balance of FGF and BMP signals regulates cell cycle exit andEquarinexpression in lens cells
inferredcites →https://doi.org/10.1093/emboj/cdf609openalex-snapshot
Altered aggregation properties of mutant γ‐crystallins cause inherited cataract
inferredcites →https://doi.org/10.1093/hmg/6.12.2109openalex-snapshot
Isolation of a New Homeobox Gene Belonging to the Pitx/Rieg Family: Expression During Lens Development and Mapping to the Aphakia Region on Mouse Chromosome 19
inferredcites →https://doi.org/10.1093/hmg/ddr014openalex-snapshot
Lens induction requires attenuation of ERK signaling by Nf1
inferredcites →https://doi.org/10.1093/nar/gkt824openalex-snapshot
Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300
inferredcites →https://doi.org/10.1096/fj.05-5532comopenalex-snapshot
Alpha‐crystallin expression affects microtubule assembly and prevents their aggregation
inferredcites →https://doi.org/10.1096/fj.10-157255openalex-snapshot
Efficient generation of lens progenitor cells and lentoid bodies from human embryonic stem cells in chemically defined conditions
inferredcites →https://doi.org/10.1098/rstb.2010.0302openalex-snapshot
Biological glass: structural determinants of eye lens transparency
inferredcites →https://doi.org/10.1101/gad.10.4.435openalex-snapshot
Multiple functions for Pax6 in mouse eye and nasal development.
inferredcites →https://doi.org/10.1101/gad.1007602openalex-snapshot
Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis
inferredcites →https://doi.org/10.1101/gad.1059403openalex-snapshot
Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development
inferredcites →https://doi.org/10.1101/gad.1087303openalex-snapshot
JNK initiates a cytokine cascade that causes Pax2 expression and closure of the optic fissure
inferredcites →https://doi.org/10.1101/gad.12.20.3162openalex-snapshot
Cooperation between the Cdk inhibitors p27 KIP1 and p57 KIP2 in the control of tissue growth and development
inferredcites →https://doi.org/10.1101/gad.12.23.3764openalex-snapshot
BMP4 is essential for lens induction in the mouse embryo
inferredcites →https://doi.org/10.1101/gad.184000openalex-snapshot
Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye
inferredcites →https://doi.org/10.1101/gad.1890410openalex-snapshot
Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity
inferredcites →https://doi.org/10.1101/gad.1909210openalex-snapshot
The Hippo–YAP pathway in organ size control and tumorigenesis: an updated version
inferredcites →https://doi.org/10.1101/gad.8.11.1285openalex-snapshot
Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development.
inferredcites →https://doi.org/10.1101/gad.887101openalex-snapshot
Pax6 and SOX2 form a co-DNA-binding partner complex that regulates initiation of lens development
inferredcites →https://doi.org/10.1101/gad.9.17.2157openalex-snapshot
Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development.
inferredcites →https://doi.org/10.1101/gad.9.22.2808openalex-snapshot
BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning.
inferredcites →https://doi.org/10.1101/gad.976502openalex-snapshot
Three habits of highly effective signaling pathways: principles of transcriptional control by developmental cell signaling
inferredcites →https://doi.org/10.1111/j.1365-2443.2007.01114.xopenalex-snapshot
PAX6 and SOX2‐dependent regulation of the Sox2 enhancer N‐3 involved in embryonic visual system development
inferredcites →https://doi.org/10.1111/j.1399-0004.2006.00619.xopenalex-snapshot
Developmental malformations of the eye: the role of PAX6, SOX2 and OTX2
inferredcites →https://doi.org/10.1111/j.1432-0436.1981.tb01141.xopenalex-snapshot
Lens Differentiation in Vertebrates
inferredcites →https://doi.org/10.1126/science.1195970openalex-snapshot
Mutations in the RNA Granule Component TDRD7 Cause Cataract and Glaucoma
inferredcites →https://doi.org/10.1126/science.3029873openalex-snapshot
Oncogenesis of the Lens in Transgenic Mice
inferredcites →https://doi.org/10.1128/mcb.00312-06openalex-snapshot
Zebra Fish Dnmt1 and Suv39h1 Regulate Organ-Specific Terminal Differentiation during Development
inferredcites →https://doi.org/10.1128/mcb.00780-07openalex-snapshot
The Notch Signaling Pathway Controls the Size of the Ocular Lens by Directly Suppressing p57Kip2 Expression
inferredcites →https://doi.org/10.1128/mcb.24.10.4241-4254.2004openalex-snapshot
Id2 and Id3 Define the Potency of Cell Proliferation and Differentiation Responses to Transforming Growth Factor β and Bone Morphogenetic Protein
inferredcites →https://doi.org/10.1128/mcb.24.24.10905-10922.2004openalex-snapshot
Abi2-Deficient Mice Exhibit Defective Cell Migration, Aberrant Dendritic Spine Morphogenesis, and Deficits in Learning and Memory
inferredcites →https://doi.org/10.1128/mcb.25.20.8854-8863.2005openalex-snapshot
Severe Defects in Proliferation and Differentiation of Lens Cells in Foxe3 Null Mice
inferredcites →https://doi.org/10.1152/physiolgenomics.00078.2001openalex-snapshot
Optical dysfunction of the crystalline lens in aquaporin-0-deficient mice
inferredcites →https://doi.org/10.1152/physrev.00034.2009openalex-snapshot
Lens Gap Junctions in Growth, Differentiation, and Homeostasis
inferredcites →https://doi.org/10.1159/000373980openalex-snapshot
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
inferredcites →https://doi.org/10.1167/iovs.03-0811openalex-snapshot
Genetic and Allelic Heterogeneity of Cryg Mutations in Eight Distinct Forms of Dominant Cataract in the Mouse
inferredcites →https://doi.org/10.1167/iovs.06-0130openalex-snapshot
A Hierarchy of Proliferative Cells Exists in Mouse Lens Epithelium: Implications for Lens Maintenance
inferredcites →https://doi.org/10.1167/iovs.06-0401openalex-snapshot
Phosphatidylinositol 3-Kinase Is Necessary for Lens Fiber Cell Differentiation and Survival
inferredcites →https://doi.org/10.1167/iovs.06-0656openalex-snapshot
Proteolytic Mechanisms Underlying Mitochondrial Degradation in the Ocular Lens
inferredcites →https://doi.org/10.1167/iovs.06-1487openalex-snapshot
γD-Crystallin–Associated Protein Aggregation and Lens Fiber Cell Denucleation
inferredcites →https://doi.org/10.1167/iovs.10-6231openalex-snapshot
Intermediate Filaments Regulate Tissue Size and Stiffness in the Murine Lens
inferredcites →https://doi.org/10.1167/iovs.11-8839openalex-snapshot
iSyTE : I ntegrated Sy stems T ool for E ye Gene Discovery
inferredcites →https://doi.org/10.1167/iovs.12-11168openalex-snapshot
Proteomics and Phosphoproteomics Analysis of Human Lens Fiber Cell Membranes
inferredcites →https://doi.org/10.1167/iovs.12-11357openalex-snapshot
Wnt-Frizzled Signaling Is Part of an FGF-Induced Cascade that Promotes Lens Fiber Differentiation
inferredcites →https://doi.org/10.1167/iovs.13-12940openalex-snapshot
Aging and Age-Related Diseases of the Ocular Lens and Vitreous Body
inferredcites →https://doi.org/10.1172/jci70877openalex-snapshot
Enhanced autophagy ameliorates cardiac proteinopathy
inferredcites →https://doi.org/10.1186/1756-8935-3-21openalex-snapshot
Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation
inferredcites →https://doi.org/10.1242/dev.001495openalex-snapshot
pygopus 2 has a crucial, Wnt pathway-independent function in lens induction
inferredcites →https://doi.org/10.1242/dev.00399openalex-snapshot
Cell-autonomous involvement ofMab21l1is essential for lens placode development
inferredcites →https://doi.org/10.1242/dev.009548openalex-snapshot
Convergence of a head-field selector Otx2 and Notch signaling: a mechanism for lens specification
inferredcites →https://doi.org/10.1242/dev.01964openalex-snapshot
A balance of FGF, BMP and WNT signalling positions the future placode territory in the head
inferredcites →https://doi.org/10.1242/dev.02022openalex-snapshot
Regulation of ocular lens development by Smad-interacting protein 1 involvingFoxe3activation
inferredcites →https://doi.org/10.1242/dev.021097openalex-snapshot
Cited2 is required for the proper formation of the hyaloid vasculature and for lens morphogenesis
inferredcites →https://doi.org/10.1242/dev.02262openalex-snapshot
Caspase-dependent secondary lens fiber cell disintegration inαA-/αB-crystallin double-knockout mice
inferredcites →https://doi.org/10.1242/dev.02328openalex-snapshot
Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning
showing the first 200 of 247 · page through all 247
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/bdr2.1050openalex-snapshot
Screening, genetics, risk factors, and treatment of neonatal cataracts
inferred← citeshttps://doi.org/10.1002/cm.21853openalex-snapshot
Disease‐related non‐muscle myosin IIA D1424N rod domain mutation, but not R702C motor domain mutation, disrupts mouse ocular lens fiber cell alignment and hexagonal packing
inferred← citeshttps://doi.org/10.1002/dvdy.24303openalex-snapshot
Deficiency of the RNA binding protein caprin2 causes lens defects and features of peters anomaly
inferred← citeshttps://doi.org/10.1002/dvdy.24677openalex-snapshot
Identification of Novel Gata3 Distal Enhancers Active in Mouse Embryonic Lens
inferred← citeshttps://doi.org/10.1002/wrna.1355openalex-snapshot
RNA ‐binding proteins in eye development and disease: implication of conserved RNA granule components
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Nager Syndrome Revisited: Integrating In Vivo and In Vitro Models to Decipher SF3B4 ‐Dependent Tissue Coordination
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Introduction: Overview of the Human Eye, Mammalian Retina, and the Retinoid Visual Cycle
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Generation of Functional Lentoid Bodies from Human-Induced Pluripotent Stem Cells
inferred← citeshttps://doi.org/10.1007/978-3-030-42634-7_188openalex-snapshot
Biology of the Transparent Lens and Changes with Age
inferred← citeshttps://doi.org/10.1007/978-3-319-42767-6_9openalex-snapshot
Vertebrate Eye Gene Regulatory Networks
inferred← citeshttps://doi.org/10.1007/978-3-319-90495-5_188-1openalex-snapshot
Biology of the Transparent Lens and Changes with Age
inferred← citeshttps://doi.org/10.1007/978-981-10-2627-0_3openalex-snapshot
Anatomy and Physiology of the Crystalline Lens
inferred← citeshttps://doi.org/10.1007/978-981-10-8746-2_5openalex-snapshot
Examining Cooperative Binding of Sox2 on DC5 Regulatory Element Upon Complex Formation with Pax6 Through Excess Electron Transfer Assay
inferred← citeshttps://doi.org/10.1007/978-981-16-6016-0_32-1openalex-snapshot
The Function of Stem Cells in Ocular Homeostasis
inferred← citeshttps://doi.org/10.1007/978-981-19-2655-6_32openalex-snapshot
The Function of Stem Cells in Ocular Homeostasis
inferred← citeshttps://doi.org/10.1007/s00417-020-04846-xopenalex-snapshot
The novel mutation P36R in LRP5L contributes to congenital membranous cataract via inhibition of laminin γ1 and c-MAF
inferred← citeshttps://doi.org/10.1007/s00439-015-1554-5openalex-snapshot
Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract
inferred← citeshttps://doi.org/10.1007/s00439-019-02084-8openalex-snapshot
High-throughput transcriptome analysis reveals that the loss of Pten activates a novel NKX6-1/RASGRP1 regulatory module to rescue microphthalmia caused by Fgfr2-deficient lenses
inferred← citeshttps://doi.org/10.1007/s10571-016-0447-zopenalex-snapshot
The Role of DNA Methylation in Lens Development and Cataract Formation
inferred← citeshttps://doi.org/10.1007/s10735-023-10177-yopenalex-snapshot
TOB1 and TOB2 mark distinct RNA processing granules in differentiating lens fiber cells
inferred← citeshttps://doi.org/10.1007/s12640-020-00325-7openalex-snapshot
Serum Aβ Levels are Associated with Age-related Cataract
inferred← citeshttps://doi.org/10.1016/b978-0-12-809633-8.90752-0openalex-snapshot
Sensory Placode Formation in Vertebrates
inferred← citeshttps://doi.org/10.1016/b978-0-12-815234-8.00009-4openalex-snapshot
Inherited Cataracts and Other Genetic Disorders of the Lens
inferred← citeshttps://doi.org/10.1016/b978-0-443-13820-1.00052-9openalex-snapshot
Lens Induction: Specification, Determination, and Placode Morphogenesis
inferred← citeshttps://doi.org/10.1016/b978-0-443-13820-1.00164-xopenalex-snapshot
Corneal Development
inferred← citeshttps://doi.org/10.1016/b978-0-7020-6616-0.00003-7openalex-snapshot
Clinical embryology and development of the eye
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2018.12.008openalex-snapshot
Eye organogenesis: A hierarchical view of ocular development
inferred← citeshttps://doi.org/10.1016/bs.pmbts.2015.05.001openalex-snapshot
Lens Development and Crystallin Gene Expression
inferred← citeshttps://doi.org/10.1016/j.ajhg.2018.09.004openalex-snapshot
Bi-allelic Loss-of-Function Variants in DNMBP Cause Infantile Cataracts
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2025.743468openalex-snapshot
Integrated brain and testis transcriptomic analyses reveal the benefits of sandy environmental enrichment in Senegalese sole male (Solea senegalensis) reproduction
inferred← citeshttps://doi.org/10.1016/j.bbadis.2020.165724openalex-snapshot
Knockout of DNase1l1l abrogates lens denucleation process and causes cataract in zebrafish
inferred← citeshttps://doi.org/10.1016/j.bbagen.2015.06.004openalex-snapshot
Differential role of arginine mutations on the structure and functions of α-crystallin
inferred← citeshttps://doi.org/10.1016/j.bbrc.2016.03.033openalex-snapshot
Membrane insertion of αA-crystallin is oligomer-size dependent
inferred← citeshttps://doi.org/10.1016/j.diff.2019.07.003openalex-snapshot
A charged multivesicular body protein (CHMP4B) is required for lens growth and differentiation
inferred← citeshttps://doi.org/10.1016/j.diff.2023.06.004openalex-snapshot
Ocular development: A view from the front to the back of the eye
inferred← citeshttps://doi.org/10.1016/j.diff.2024.100792openalex-snapshot
Lens Placode Modulates Extracellular Matrix Formation During Early Eye Development
inferred← citeshttps://doi.org/10.1016/j.exer.2015.02.004openalex-snapshot
Fibrosis in the lens. Sprouty regulation of TGFβ-signaling prevents lens EMT leading to cataract
inferred← citeshttps://doi.org/10.1016/j.exer.2016.03.010openalex-snapshot
Systems biology of lens development: A paradigm for disease gene discovery in the eye
inferred← citeshttps://doi.org/10.1016/j.exer.2016.04.017openalex-snapshot
PAX6: 25th anniversary and more to learn
inferred← citeshttps://doi.org/10.1016/j.exer.2018.01.009openalex-snapshot
Express: A database of transcriptome profiles encompassing known and novel transcripts across multiple development stages in eye tissues
inferred← citeshttps://doi.org/10.1016/j.exer.2018.06.004openalex-snapshot
A comprehensive spatial-temporal transcriptomic analysis of differentiating nascent mouse lens epithelial and fiber cells
inferred← citeshttps://doi.org/10.1016/j.exer.2018.10.011openalex-snapshot
Proteome-transcriptome analysis and proteome remodeling in mouse lens epithelium and fibers
inferred← citeshttps://doi.org/10.1016/j.exer.2020.108279openalex-snapshot
Analysis of lens epithelium telomere length in age-related cataract
inferred← citeshttps://doi.org/10.1016/j.exer.2021.108564openalex-snapshot
Crystallin gene expression: Insights from studies of transcriptional bursting
inferred← citeshttps://doi.org/10.1016/j.exer.2021.108693openalex-snapshot
Functional integration of eye tissues and refractive eye development: Mechanisms and pathways
inferred← citeshttps://doi.org/10.1016/j.exer.2023.109603openalex-snapshot
The molecular genetics of anterior segment dysgenesis
inferred← citeshttps://doi.org/10.1016/j.exer.2025.110347openalex-snapshot
CD24 is required for sustained transparency of the adult lens
inferred← citeshttps://doi.org/10.1016/j.gene.2016.10.020openalex-snapshot
Comparative analysis of the neurula transcriptomes of two species of flatfishes: Platichthys stellatus and Paralichthys olivaceus
inferred← citeshttps://doi.org/10.1016/j.jbc.2022.102537openalex-snapshot
Insights into the biochemical and biophysical mechanisms mediating the longevity of the transparent optics of the eye lens
inferred← citeshttps://doi.org/10.1016/j.jbc.2024.108064openalex-snapshot
The transcription factor CREB regulates epithelial-mesenchymal transition of lens epithelial cells by phosphorylation-dependent and phosphorylation-independent mechanisms
inferred← citeshttps://doi.org/10.1016/j.jtbi.2015.03.021openalex-snapshot
A stochastic model of eye lens growth
inferred← citeshttps://doi.org/10.1016/j.jtos.2021.08.010openalex-snapshot
Impaired GSH biosynthesis disrupts eye development, lens morphogenesis and PAX6 function
inferred← citeshttps://doi.org/10.1016/j.jtos.2021.09.001openalex-snapshot
Pathophysiology of aniridia-associated keratopathy: Developmental aspects and unanswered questions
inferred← citeshttps://doi.org/10.1016/j.micron.2023.103446openalex-snapshot
Cellular activity of autophagy and multivesicular bodies in lens fiber cells during early lens development in rbm24a mutant of zebrafish: Ultrastructure analysis
inferred← citeshttps://doi.org/10.1016/j.omtn.2017.09.011openalex-snapshot
A New Long Noncoding RNA ALB Regulates Autophagy by Enhancing the Transformation of LC3BI to LC3BII during Human Lens Development
inferred← citeshttps://doi.org/10.1016/j.pbiomolbio.2018.01.004openalex-snapshot
How mechanical forces shape the developing eye
inferred← citeshttps://doi.org/10.1016/j.preteyeres.2016.08.001openalex-snapshot
Autophagy in the eye: Development, degeneration, and aging
inferred← citeshttps://doi.org/10.1016/j.preteyeres.2022.101093openalex-snapshot
Cell fate decisions, transcription factors and signaling during early retinal development
inferred← citeshttps://doi.org/10.1016/j.preteyeres.2022.101112openalex-snapshot
The lens epithelium as a major determinant in the development, maintenance, and regeneration of the crystalline lens
inferred← citeshttps://doi.org/10.1016/j.preteyeres.2022.101133openalex-snapshot
Congenital aniridia beyond black eyes: From phenotype and novel genetic mechanisms to innovative therapeutic approaches
inferred← citeshttps://doi.org/10.1016/j.preteyeres.2026.101446openalex-snapshot
Lens aging and disease: Molecular mechanisms, functional consequences, and pharmacological implications
inferred← citeshttps://doi.org/10.1016/j.reprotox.2022.06.008openalex-snapshot
Disruption of fetal eye development caused by insulin-induced maternal hypoglycemia in rats
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2024.171133openalex-snapshot
Aggravated visual toxicity in zebrafish larvae upon co-exposure to titanium dioxide nanoparticles and bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate
inferred← citeshttps://doi.org/10.1016/j.semcdb.2022.06.009openalex-snapshot
Making a head: Neural crest and ectodermal placodes in cranial sensory development
inferred← citeshttps://doi.org/10.1016/j.tig.2017.08.001openalex-snapshot
Signaling and Gene Regulatory Networks in Mammalian Lens Development
inferred← citeshttps://doi.org/10.1016/j.ydbio.2015.06.022openalex-snapshot
Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis
inferred← citeshttps://doi.org/10.1016/j.ydbio.2015.10.005openalex-snapshot
The endocytic recycling regulatory protein EHD1 Is required for ocular lens development
inferred← citeshttps://doi.org/10.1016/j.ydbio.2017.05.026openalex-snapshot
Six3 in a small population of progenitors at E8.5 is required for neuroretinal specification via regulating cell signaling and survival in mice
inferred← citeshttps://doi.org/10.1016/j.ydbio.2017.07.002openalex-snapshot
N-myc regulates growth and fiber cell differentiation in lens development
inferred← citeshttps://doi.org/10.1016/j.ydbio.2017.09.030openalex-snapshot
Pax6 is essential for the generation of late-born retinal neurons and for inhibition of photoreceptor-fate during late stages of retinogenesis
inferred← citeshttps://doi.org/10.1016/j.ydbio.2018.12.016openalex-snapshot
Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth
inferred← citeshttps://doi.org/10.1016/j.ydbio.2019.03.010openalex-snapshot
Desmoplakin is required for epidermal integrity and morphogenesis in the Xenopus laevis embryo
inferred← citeshttps://doi.org/10.1016/j.ydbio.2019.04.020openalex-snapshot
Lens differentiation is characterized by stage-specific changes in chromatin accessibility correlating with differentiation state-specific gene expression
inferred← citeshttps://doi.org/10.1016/j.ydbio.2019.10.020openalex-snapshot
Lysyl hydroxylase 3 is required for normal lens capsule formation and maintenance of lens epithelium integrity and fate
inferred← citeshttps://doi.org/10.1016/j.ydbio.2020.02.014openalex-snapshot
Formation and contraction of multicellular actomyosin cables facilitate lens placode invagination
inferred← citeshttps://doi.org/10.1016/j.ydbio.2021.09.002openalex-snapshot
Local tissue interactions govern pLL patterning in medaka
inferred← citeshttps://doi.org/10.1016/j.ydbio.2026.04.006openalex-snapshot
Meis1 and Meis2 are jointly required for advanced stages of mouse lens morphogenesis
inferred← citeshttps://doi.org/10.1016/j.ydbio.2026.04.017openalex-snapshot
RNA-binding proteins in the mouse lens: Functional classifications, expression profiling, and interaction studies of Carhsp1 with crystallin mRNAs
inferred← citeshttps://doi.org/10.1016/s0246-0343(22)83982-4openalex-snapshot
10.1016/s0246-0343(22)83982-4
inferred← citeshttps://doi.org/10.1021/bk-2020-1346.ch009openalex-snapshot
Morphogenesis of the Mammalian Tectorial Membrane: Unveiling the Surface Roles of a Matrix Organizer, Alpha Tectorin
inferred← citeshttps://doi.org/10.1038/d41586-021-00888-1openalex-snapshot
Lipid dismantling of lens organelles for clear vision
inferred← citeshttps://doi.org/10.1038/s41419-020-03090-9openalex-snapshot
ATRIP protects progenitor cells against DNA damage in vivo
inferred← citeshttps://doi.org/10.1038/s41433-021-01711-xopenalex-snapshot
Variants in PAX6, PITX3 and HSF4 causing autosomal dominant congenital cataracts
inferred← citeshttps://doi.org/10.1038/s41433-025-04110-8openalex-snapshot
Pathobiology of the developing eye lens: regulation of intracellular MAPK-signalling pathways to prevent lens dysplasia
inferred← citeshttps://doi.org/10.1038/s41467-021-22782-0openalex-snapshot
Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency
inferred← citeshttps://doi.org/10.1038/s41467-024-54184-3openalex-snapshot
Ecological diversification of sea catfishes is accompanied by genome-wide signatures of positive selection
inferred← citeshttps://doi.org/10.1038/s41598-017-04936-7openalex-snapshot
Nuclear receptors connect progenitor transcription factors to cell cycle control
inferred← citeshttps://doi.org/10.1038/s41598-017-10615-4openalex-snapshot
Transcriptome analysis of developing lens reveals abundance of novel transcripts and extensive splicing alterations
inferred← citeshttps://doi.org/10.1038/s42003-025-08722-4openalex-snapshot
Periaxin gene variants are linked to age-related cataracts in Cx46 deficient lenses
inferred← citeshttps://doi.org/10.1038/s42003-025-09159-5openalex-snapshot
In vivo imaging reveals exosome-mediated intercellular communication in lens development
inferred← citeshttps://doi.org/10.1073/pnas.1917922117openalex-snapshot
Rbm24 controls poly(A) tail length and translation efficiency of crystallin mRNAs in the lens via cytoplasmic polyadenylation
inferred← citeshttps://doi.org/10.1074/jbc.m115.705103openalex-snapshot
Regulation of c-Maf and αA-Crystallin in Ocular Lens by Fibroblast Growth Factor Signaling
inferred← citeshttps://doi.org/10.1074/jbc.ra118.001927openalex-snapshot
Transcriptional burst fraction and size dynamics during lens fiber cell differentiation and detailed insights into the denucleation process
inferred← citeshttps://doi.org/10.1074/jbc.ra119.008853openalex-snapshot
Transcriptional profiling of single fiber cells in a transgenic paradigm of an inherited childhood cataract reveals absence of molecular heterogeneity
inferred← citeshttps://doi.org/10.1074/jbc.ra119.009052openalex-snapshot
The l-isoaspartate modification within protein fragments in the aging lens can promote protein aggregation
inferred← citeshttps://doi.org/10.1074/jbc.ra120.012715openalex-snapshot
Implications of RNG140 (caprin2)-mediated translational regulation in eye lens differentiation
inferred← citeshttps://doi.org/10.1080/15548627.2021.1872188openalex-snapshot
Rapamycin relieves the cataract caused by ablation of Gja8b through stimulating autophagy in zebrafish
inferred← citeshttps://doi.org/10.1080/27694127.2023.2178996openalex-snapshot
Autophagy in the eye: from physiology to pathophysiology
inferred← citeshttps://doi.org/10.1088/1478-3975/aa8d0eopenalex-snapshot
Apoptosis generates mechanical forces that close the lens vesicle in the chick embryo
inferred← citeshttps://doi.org/10.1091/mbc.e16-12-0865openalex-snapshot
Dual function of TGFβ in lens epithelial cell fate: implications for secondary cataract
inferred← citeshttps://doi.org/10.1091/mbc.e23-07-0294openalex-snapshot
Tonic ErbB signaling underlies TGFβ-induced activation of ERK and is required for lens cell epithelial to myofibroblast transition
inferred← citeshttps://doi.org/10.1091/mbc.e24-01-0040openalex-snapshot
TGFβ overcomes FGF-induced transinhibition of EGFR in lens cells to enable fibrotic secondary cataract
inferred← citeshttps://doi.org/10.1093/bib/bbag103openalex-snapshot
An integrative association analysis for complex diseases in underrepresented groups by leveraging the trans-ethnic genetic similarity
inferred← citeshttps://doi.org/10.1093/gbe/evx153openalex-snapshot
Evolutionary Origins of Pax6 Control of Crystallin Genes
inferred← citeshttps://doi.org/10.1093/hmg/ddaa096openalex-snapshot
The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology
inferred← citeshttps://doi.org/10.1093/nar/gkv589openalex-snapshot
Identification ofin vivoDNA-binding mechanisms of Pax6 and reconstruction of Pax6-dependent gene regulatory networks during forebrain and lens development
inferred← citeshttps://doi.org/10.1093/nar/gkw478openalex-snapshot
Examining cooperative binding of Sox2 on DC5 regulatory element upon complex formation with Pax6 through excess electron transfer assay
inferred← citeshttps://doi.org/10.1093/nar/gkx837openalex-snapshot
iSyTE 2.0: a database for expression-based gene discovery in the eye
inferred← citeshttps://doi.org/10.1096/fj.202201368rropenalex-snapshot
Charged multivesicular body protein 4b forms complexes with gap junction proteins during lens fiber cell differentiation
inferred← citeshttps://doi.org/10.1098/rsob.190220openalex-snapshot
Transcriptomic analysis and novel insights into lens fibre cell differentiation regulated by Gata3
inferred← citeshttps://doi.org/10.1101/2020.02.05.935189openalex-snapshot
Foxg1 Organizes Cephalic Ectoderm to Repress Mandibular Fate, Regulate Apoptosis, Generate Choanae, Elaborate the Auxiliary Eye and Pattern the Upper Jaw
inferred← citeshttps://doi.org/10.1101/2020.03.26.009969openalex-snapshot
Tissue interactions govern pattern formation in the posterior lateral line of medaka
inferred← citeshttps://doi.org/10.1101/2024.01.26.577383openalex-snapshot
Supercontinuum intrinsic fluorescence imaging heralds free view of living systems
inferred← citeshttps://doi.org/10.1101/2025.04.17.649366openalex-snapshot
Inverted Assembly of the Lens Within Ocular Organoids Reveals Alternate Paths to Ocular Morphogenesis
inferred← citeshttps://doi.org/10.1101/2025.10.23.684166openalex-snapshot
Pax6 maintains lens epithelial cell identity and coordinates secondary fiber cell differentiation
inferred← citeshttps://doi.org/10.1101/700591openalex-snapshot
Gclc deletion in surface-ectoderm tissues induces microphthalmia
inferred← citeshttps://doi.org/10.1111/jnc.13406openalex-snapshot
The transcription factor Pax6 contributes to the induction of GLT‐1 expression in astrocytes through an interaction with a distal enhancer element
inferred← citeshttps://doi.org/10.1111/joa.12318openalex-snapshot
Dynamic expression patterns of P ax6 during spermatogenesis in the mouse
inferred← citeshttps://doi.org/10.1134/s1062360420050033openalex-snapshot
mRNAs of Genes of Toll-Like Receptors are Expressed in Human Fetal Eye Tissues
inferred← citeshttps://doi.org/10.1136/bjophthalmol-2019-315282openalex-snapshot
Inherited cataracts: molecular genetics, clinical features, disease mechanisms and novel therapeutic approaches
inferred← citeshttps://doi.org/10.1146/annurev-genom-102722-090617openalex-snapshot
The Genetic Determinants of Axial Length: From Microphthalmia to High Myopia in Childhood
inferred← citeshttps://doi.org/10.11606/d.41.2022.tde-22032023-114202openalex-snapshot
Padrões contrastantes de expressão gênica ao longo do desenvolvimento do olho entre girinos fossoriais e bentônicos
inferred← citeshttps://doi.org/10.11606/t.42.2023.tde-22082023-161002openalex-snapshot
Sinalização BMP e modulação da matriz extracelular durante a embriogênese óptica
inferred← citeshttps://doi.org/10.1162/leon_a_01738openalex-snapshot
Drawing to Extend Waddington's Epigenetic Landscape
inferred← citeshttps://doi.org/10.1167/iovs.16-20504openalex-snapshot
Generation of Functional Lentoid Bodies From Human Induced Pluripotent Stem Cells Derived From Urinary Cells
inferred← citeshttps://doi.org/10.1167/iovs.18-23902openalex-snapshot
Wnt5a Contributes to the Differentiation of Human Embryonic Stem Cells into Lentoid Bodies Through the Noncanonical Wnt/JNK Signaling Pathway
inferred← citeshttps://doi.org/10.1167/iovs.18-25175openalex-snapshot
Altered Signaling Pathways in Aniridia-Related Keratopathy
inferred← citeshttps://doi.org/10.1167/iovs.18-25921openalex-snapshot
Bidirectional Analysis of Cryba4-Crybb1 Nascent Transcription and Nuclear Accumulation of Crybb3 mRNAs in Lens Fibers
inferred← citeshttps://doi.org/10.1167/iovs.19-26728openalex-snapshot
Characterization of LSD1 Expression Within the Murine Eye
inferred← citeshttps://doi.org/10.1167/iovs.61.12.21openalex-snapshot
Heterozygous Loss of Yap1 in Mice Causes Progressive Cataracts
inferred← citeshttps://doi.org/10.1167/iovs.63.10.1openalex-snapshot
Deficiency of Jamc Leads to Congenital Nuclear Cataract and Activates the Unfolded Protein Response in Mouse Lenses
inferred← citeshttps://doi.org/10.1167/iovs.63.4.18openalex-snapshot
Znhit1 Regulates p21 Cip1 to Control Mouse Lens Differentiation
inferred← citeshttps://doi.org/10.1167/iovs.64.10.6openalex-snapshot
ErbBs in Lens Cell Fibrosis and Secondary Cataract
inferred← citeshttps://doi.org/10.1167/iovs.64.13.37openalex-snapshot
Single-Cell RNA Sequencing Analysis of the Early Postnatal Mouse Lens Epithelium
inferred← citeshttps://doi.org/10.1167/iovs.64.15.15openalex-snapshot
JAM-C Is Important for Lens Epithelial Cell Proliferation and Lens Fiber Maturation in Murine Lens Development
inferred← citeshttps://doi.org/10.1167/iovs.64.7.5openalex-snapshot
HSF4 Transcriptionally Activates Autophagy by Regulating ATG9a During Lens Terminal Differentiation
inferred← citeshttps://doi.org/10.1167/iovs.65.10.12openalex-snapshot
Biologically Relevant Laminin-511 Moderates the Derivation and Proliferation of Human Lens Epithelial Stem/Progenitor-Like Cells
inferred← citeshttps://doi.org/10.1167/iovs.65.4.4openalex-snapshot
Dysregulation of Autophagy Occurs During Congenital Cataract Development in βA3ΔG91 Mice
inferred← citeshttps://doi.org/10.1167/iovs.66.14.28openalex-snapshot
Abnormal Splicing in the Final Intron of PRX Results in Dominant Congenital Cataract Without Neurological Phenotype
inferred← citeshttps://doi.org/10.1167/iovs.66.9.45openalex-snapshot
Mettl3 Regulates Lens Development by Promoting the Differentiation Processes of Secondary Fiber Cells
inferred← citeshttps://doi.org/10.1167/iovs.67.1.50openalex-snapshot
The Structural Order of Crystallin Proteins During Early Human Lens Development
inferred← citeshttps://doi.org/10.1167/tvst.10.10.4openalex-snapshot
In Vivo Imaging of Newt Lens Regeneration: Novel Insights Into the Regeneration Process
inferred← citeshttps://doi.org/10.1177/2633004021997447openalex-snapshot
Animal and cellular models of microphthalmia
inferred← citeshttps://doi.org/10.1186/s11658-025-00827-2openalex-snapshot
Loss of alpha-kinase 1 contributes to the formation of congenital cataracts in mice
inferred← citeshttps://doi.org/10.1186/s12915-021-01182-2openalex-snapshot
Co-option of the limb patterning program in cephalopod eye development
inferred← citeshttps://doi.org/10.1186/s13062-026-00821-4openalex-snapshot
The role of autophagy in ocular health: mechanisms, pathologies, and therapeutic strategies
inferred← citeshttps://doi.org/10.1186/s13072-016-0087-zopenalex-snapshot
Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers
inferred← citeshttps://doi.org/10.1186/s13072-019-0272-yopenalex-snapshot
Profiling of chromatin accessibility and identification of general cis-regulatory mechanisms that control two ocular lens differentiation pathways
inferred← citeshttps://doi.org/10.1186/s13072-022-00440-zopenalex-snapshot
Changes in DNA methylation hallmark alterations in chromatin accessibility and gene expression for eye lens differentiation
inferred← citeshttps://doi.org/10.1186/s13072-023-00478-7openalex-snapshot
Dynamic changes in whole genome DNA methylation, chromatin and gene expression during mouse lens differentiation
inferred← citeshttps://doi.org/10.1186/s13072-024-00533-xopenalex-snapshot
Analysis of long-range chromatin contacts, compartments and looping between mouse embryonic stem cells, lens epithelium and lens fibers
inferred← citeshttps://doi.org/10.1186/s13287-022-02862-8openalex-snapshot
Nicotinamide improves in vitro lens regeneration in a mouse capsular bag model
inferred← citeshttps://doi.org/10.1186/s40246-019-0248-9openalex-snapshot
Genetics and functions of the retinoic acid pathway, with special emphasis on the eye
inferred← citeshttps://doi.org/10.1242/dev.134254openalex-snapshot
Eye development and photoreceptor differentiation in the cephalopod Doryteuthis pealeii
inferred← citeshttps://doi.org/10.1242/dev.135285openalex-snapshot
Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation
inferred← citeshttps://doi.org/10.1242/dev.182923openalex-snapshot
Evolution and development of complex eyes: a celebration of diversity
inferred← citeshttps://doi.org/10.1242/dmm.049251openalex-snapshot
MAB21L1 modulates gene expression and DNA metabolic processes in the lens placode
inferred← citeshttps://doi.org/10.1242/jcs.217240openalex-snapshot
Fibronectin regulates growth factor signaling and cell differentiation in primary lens cells
inferred← citeshttps://doi.org/10.1242/jcs.262349openalex-snapshot
Ankyrin-B is required for the establishment and maintenance of lens cytoarchitecture, mechanics and clarity
inferred← citeshttps://doi.org/10.1369/00221554241272338openalex-snapshot
Differential Expression of Branched-Chain Aminotransferase in the Rat Ocular Tissues
inferred← citeshttps://doi.org/10.1371/journal.pgen.1006441openalex-snapshot
The Gene Regulatory Network of Lens Induction Is Wired through Meis-Dependent Shadow Enhancers of Pax6
inferred← citeshttps://doi.org/10.1371/journal.pgen.1007278openalex-snapshot
The RNA-binding protein Celf1 post-transcriptionally regulates p27Kip1 and Dnase2b to control fiber cell nuclear degradation in lens development
inferred← citeshttps://doi.org/10.1371/journal.pone.0160785openalex-snapshot
Identification and Ultrastructural Characterization of a Novel Nuclear Degradation Complex in Differentiating Lens Fiber Cells
inferred← citeshttps://doi.org/10.1371/journal.pone.0197048openalex-snapshot
Ciliary margin-derived BMP4 does not have a major role in ocular development
inferred← citeshttps://doi.org/10.1371/journal.pone.0214758openalex-snapshot
Rhabdomyosarcoma and Wilms tumors contain a subpopulation of noggin producing, myogenic cells immunoreactive for lens beaded filament proteins
inferred← citeshttps://doi.org/10.1371/journal.pone.0340185openalex-snapshot
Characterization of a spontaneous microphthalmia-like mutant mouse with isolated ocular defects
inferred← citeshttps://doi.org/10.1387/ijdb.180084nvopenalex-snapshot
Lens regeneration: a historical perspective
inferred← citeshttps://doi.org/10.17760/d20486926openalex-snapshot
Illuminating assembly dynamics regulating short-range order optics in extremely long-lived proteins
inferred← citeshttps://doi.org/10.18008/1816-5095-2022-1-33-37openalex-snapshot
Capsular Contraction Syndrome. Review. Part 1
inferred← citeshttps://doi.org/10.18632/aging.204203openalex-snapshot
MAB21L1 promotes survival of lens epithelial cells through control of αB-crystallin and ATR/CHK1/p53 pathway
inferred← citeshttps://doi.org/10.21037/atm-2019-rcs-03openalex-snapshot
Lens regeneration in humans: using regenerative potential for tissue repairing
inferred← citeshttps://doi.org/10.21203/rs.3.rs-367664/v1openalex-snapshot
Variants in PAX6, PITX3 and HSF4 Causing Autosomal Dominant Congenital Cataract
inferred← citeshttps://doi.org/10.2174/1566524019666190111153310openalex-snapshot
Analysis of Non-Sumoylated and Sumoylated Isoforms of Pax-6, the Master Regulator for Eye and Brain Development in Ocular Cell Lines
inferred← citeshttps://doi.org/10.2174/1574888x18666230313094121openalex-snapshot
Corneal Epithelial Development and the Role of Induced Pluripotent Stem Cells for Regeneration
inferred← citeshttps://doi.org/10.23736/s0393-3660.23.05076-3openalex-snapshot
Expression of mRNA forkhead box protein e3 (FoxE3) in congenital cataracts: a cross-sectional study
inferred← citeshttps://doi.org/10.24875/gmm.17002604openalex-snapshot
Genes relacionados con microftalmia y anoftalmia hereditarias
inferred← citeshttps://doi.org/10.24875/gmm.m18000089openalex-snapshot
Genes related to inherited microphthalmia and anophthalmia
inferred← citeshttps://doi.org/10.3389/fcell.2016.00138openalex-snapshot
WNT/β-Catenin Signaling in Vertebrate Eye Development
inferred← citeshttps://doi.org/10.3389/fcell.2020.620735openalex-snapshot
Insights Into the Complexity of Craniofacial Development From a Cellular Perspective
inferred← citeshttps://doi.org/10.3389/fcell.2021.660494openalex-snapshot
The E3 Ligase PIAS1 Regulates p53 Sumoylation to Control Stress-Induced Apoptosis of Lens Epithelial Cells Through the Proapoptotic Regulator Bax
inferred← citeshttps://doi.org/10.3389/fcell.2022.794837openalex-snapshot
Identification of a New Mutation p.P88L in Connexin 50 Associated with Dominant Congenital Cataract
inferred← citeshttps://doi.org/10.3389/fcell.2022.820949openalex-snapshot
A possible connection between reactive oxygen species and the unfolded protein response in lens development: From insight to foresight
inferred← citeshttps://doi.org/10.3389/fcell.2022.840129openalex-snapshot
Arvcf Dependent Adherens Junction Stability is Required to Prevent Age-Related Cortical Cataracts
inferred← citeshttps://doi.org/10.3389/fcell.2024.1359207openalex-snapshot
Sensory cells in tunicates: insights into mechanoreceptor evolution
inferred← citeshttps://doi.org/10.3389/fcell.2025.1524814openalex-snapshot
The role of the Hippo/YAP pathway in the physiological activities and lesions of lens epithelial cells
inferred← citeshttps://doi.org/10.3389/fcell.2025.1552988openalex-snapshot
Zebrafish as a model for crystallin-associated congenital cataracts in humans
inferred← citeshttps://doi.org/10.3389/fimmu.2017.00480openalex-snapshot
The Transcription Factor c-Maf Promotes the Differentiation of Follicular Helper T Cells
inferred← citeshttps://doi.org/10.3389/fopht.2024.1434327openalex-snapshot
The significance of growth shells in development of symmetry, transparency, and refraction of the human lens
inferred← citeshttps://doi.org/10.3389/fopht.2026.1949916openalex-snapshot
Global challenges for lens and cataract research
inferred← citeshttps://doi.org/10.3389/fphys.2017.00936openalex-snapshot
Early Determination of the Periodontal Domain by the Wnt-Antagonist Frzb/Sfrp3
inferred← citeshttps://doi.org/10.3390/app112110151openalex-snapshot
Spatiotemporal Protein Expression Profiles of QSOX1 in the Murine Uterus, Placenta, and Embryo during Pregnancy
inferred← citeshttps://doi.org/10.3390/biom13040693openalex-snapshot
Multiomics Analysis Reveals Novel Genetic Determinants for Lens Differentiation, Structure, and Transparency
inferred← citeshttps://doi.org/10.3390/biomedicines11010198openalex-snapshot
Timeline of Developmental Defects Generated upon Genetic Inhibition of the Retinoic Acid Receptor Signaling Pathway
inferred← citeshttps://doi.org/10.3390/cells10102604openalex-snapshot
Insights into Bone Morphogenetic Protein—(BMP-) Signaling in Ocular Lens Biology and Pathology
inferred← citeshttps://doi.org/10.3390/cells10102606openalex-snapshot
Mutation of the EPHA2 Tyrosine-Kinase Domain Dysregulates Cell Pattern Formation and Cytoskeletal Gene Expression in the Lens
inferred← citeshttps://doi.org/10.3390/cells11213516openalex-snapshot
Generation of Lens Progenitor Cells and Lentoid Bodies from Pluripotent Stem Cells: Novel Tools for Human Lens Development and Ocular Disease Etiology
inferred← citeshttps://doi.org/10.3390/cells12101364openalex-snapshot
Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis
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