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Tissue-specific genome editing in Ciona embryos by CRISPR/Cas9

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/dvdy.20815openalex-snapshot
Predictable mosaic transgene expression in ascidian embryos produced with a simple electroporation device
inferredcites →https://doi.org/10.1002/dvg.22770openalex-snapshot
Germ cell mutations of the ascidian Ciona intestinalis with TALE nucleases
inferredcites →https://doi.org/10.1002/gene.10119openalex-snapshot
A cDNA resource from the basal chordate Ciona intestinalis
inferredcites →https://doi.org/10.1006/dbio.1997.8772openalex-snapshot
Developmental Fates of Larval Tissues after Metamorphosis in AscidianHalocynthia roretzi
inferredcites →https://doi.org/10.1007/978-1-60761-753-2_15openalex-snapshot
A Rapid and General Assay for Monitoring Endogenous Gene Modification
inferredcites →https://doi.org/10.1007/s00438-009-0500-4openalex-snapshot
Maternal factor-mediated epigenetic gene silencing in the ascidian Ciona intestinalis
inferredcites →https://doi.org/10.1016/j.cell.2013.02.022openalex-snapshot
Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
inferredcites →https://doi.org/10.1016/j.cell.2013.04.025openalex-snapshot
One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
inferredcites →https://doi.org/10.1016/j.cell.2013.08.022openalex-snapshot
One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering
inferredcites →https://doi.org/10.1016/j.cell.2013.12.001openalex-snapshot
Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System
inferredcites →https://doi.org/10.1016/j.devcel.2014.04.001openalex-snapshot
Collier/OLF/EBF-Dependent Transcriptional Dynamics Control Pharyngeal Muscle Specification from Primed Cardiopharyngeal Progenitors
inferredcites →https://doi.org/10.1016/s0960-9822(98)70084-3openalex-snapshot
XCoe2, a transcription factor of the Col/Olf-1/EBF family involved in the specification of primary neurons in Xenopus
inferredcites →https://doi.org/10.1038/nbt.2501openalex-snapshot
Efficient genome editing in zebrafish using a CRISPR-Cas system
inferredcites →https://doi.org/10.1038/nbt.2647openalex-snapshot
DNA targeting specificity of RNA-guided Cas9 nucleases
inferredcites →https://doi.org/10.1038/nbt.2889openalex-snapshot
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells
inferredcites →https://doi.org/10.1038/nmeth.2532openalex-snapshot
Heritable genome editing in C. elegans via a CRISPR-Cas9 system
inferredcites →https://doi.org/10.1038/nmeth.2641openalex-snapshot
Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination
inferredcites →https://doi.org/10.1038/nn.2989openalex-snapshot
Coordinated regulation of cholinergic motor neuron traits through a conserved terminal selector gene
inferredcites →https://doi.org/10.1038/nprot.2013.143openalex-snapshot
Genome engineering using the CRISPR-Cas9 system
inferredcites →https://doi.org/10.1093/gbe/evs054openalex-snapshot
The Population Genomics of a Fast Evolver: High Levels of Diversity, Functional Constraint, and Molecular Adaptation in the Tunicate Ciona intestinalis
inferredcites →https://doi.org/10.1101/pdb.prot5344openalex-snapshot
Isolation of Sea Squirt (Ciona) Gametes, Fertilization, Dechorionation, and Development: Figure 1.
inferredcites →https://doi.org/10.1101/pdb.prot5345openalex-snapshot
Electroporation of Transgenic DNAs in the Sea Squirt Ciona
inferredcites →https://doi.org/10.1101/pdb.prot5348openalex-snapshot
Whole-Mount In Situ Hybridization on Sea Squirt (Ciona intestinalis) Embryos
inferredcites →https://doi.org/10.1101/pdb.prot5349openalex-snapshot
Isolation of Individual Cells and Tissues from Electroporated Sea Squirt (Ciona) Embryos by Fluorescence-Activated Cell Sorting (FACS)
inferredcites →https://doi.org/10.1111/dgd.12149openalex-snapshot
CRISPR / C as9‐mediated gene knockout in the ascidian C iona intestinalis
inferredcites →https://doi.org/10.1111/j.1440-169x.2008.01039.xopenalex-snapshot
RNA interference by expressing short hairpin RNA in the Ciona intestinalis embryo
inferredcites →https://doi.org/10.1111/j.1440-169x.2012.01355.xopenalex-snapshot
Efficient targeted mutagenesis of the chordate C iona intestinalis genome with zinc‐finger nucleases
inferredcites →https://doi.org/10.1126/science.1138140openalex-snapshot
CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes
inferredcites →https://doi.org/10.1126/science.1159689openalex-snapshot
Small CRISPR RNAs Guide Antiviral Defense in Prokaryotes
inferredcites →https://doi.org/10.1126/science.1165771openalex-snapshot
CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA
inferredcites →https://doi.org/10.1126/science.1190181openalex-snapshot
Early Chordate Origins of the Vertebrate Second Heart Field
inferredcites →https://doi.org/10.1126/science.1225829openalex-snapshot
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
inferredcites →https://doi.org/10.1126/science.1231143openalex-snapshot
Multiplex Genome Engineering Using CRISPR/Cas Systems
inferredcites →https://doi.org/10.1126/science.1232033openalex-snapshot
RNA-Guided Human Genome Engineering via Cas9
inferredcites →https://doi.org/10.1242/dev.010140openalex-snapshot
FoxFis essential for FGF-induced migration of heart progenitor cells in the ascidianCiona intestinalis
inferredcites →https://doi.org/10.1242/dev.02051openalex-snapshot
Uncoupling heart cell specification and migration in the simple chordateCiona intestinalis
inferredcites →https://doi.org/10.1242/dev.026419openalex-snapshot
Gene regulatory networks underlying the compartmentalization of theCionacentral nervous system
inferredcites →https://doi.org/10.1242/dev.061507openalex-snapshot
Neuronal subtype specification in the spinal cord of a protovertebrate
inferredcites →https://doi.org/10.1242/dev.092361openalex-snapshot
Neuronal subtype specification in the spinal cord of a protovertebrate
inferredcites →https://doi.org/10.1242/dev.099572openalex-snapshot
Tissue-specific and ubiquitous gene knockouts by TALEN electroporation provide new approaches to investigating gene function in Ciona
inferredcites →https://doi.org/10.1242/dev.124.3.589openalex-snapshot
Characterization of a notochord-specific enhancer from the Brachyury promoter region of the ascidian, Ciona intestinalis
inferredcites →https://doi.org/10.1242/dev.126.7.1495openalex-snapshot
Requirement for the Drosophila COE transcription factor Collier in formation of an embryonic muscle: transcriptional response to Notch signalling
inferredcites →https://doi.org/10.1371/journal.pbio.1001725openalex-snapshot
NK4 Antagonizes Tbx1/10 to Promote Cardiac versus Pharyngeal Muscle Fate in the Ascidian Second Heart Field
inferredcites →https://doi.org/10.1371/journal.pone.0000916openalex-snapshot
A Multicassette Gateway Vector Set for High Throughput and Comparative Analyses in Ciona and Vertebrate Embryos
inferredcites →https://doi.org/10.1534/genetics.112.140590openalex-snapshot
Genetic and Genomic Toolbox of the Chordate Ciona intestinalis
inferredcites →https://doi.org/10.2108/zsj.27.181openalex-snapshot
Simple Motor System of the Ascidian Larva: Neuronal Complex Comprising Putative Cholinergic and GABAergic/Glycinergic Neurons
inferredcites →https://doi.org/10.7554/elife.03728openalex-snapshot
Divergent mechanisms regulate conserved cardiopharyngeal development and gene expression in distantly related ascidians

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Adenoviral Vector-Mediated NGF Gene Therapy for a Rat Model of Diabetic Bladder Dysfunction
inferred← citeshttps://doi.org/10.1002/dvg.22843openalex-snapshot
CRISPR / C as9‐mediated genome modification in the mollusc, Crepidula fornicata
inferred← citeshttps://doi.org/10.1002/dvg.23260openalex-snapshot
Efficient genome editing using CRISPR‐Cas‐mediated homology directed repair in the ascidian Ciona robusta
inferred← citeshttps://doi.org/10.1002/mrd.22661openalex-snapshot
Gonad development and hermaphroditism in the ascidian Botryllus schlosseri
inferred← citeshttps://doi.org/10.1002/wdev.239openalex-snapshot
The central nervous system of ascidian larvae
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Formation of adult organs through metamorphosis in ascidians
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Functional genomic approaches to elucidate the role of enhancers during development
inferred← citeshttps://doi.org/10.1007/978-1-0716-3016-7_28openalex-snapshot
Improved Genome Editing in the Ascidian Ciona with CRISPR/Cas9 and TALEN
inferred← citeshttps://doi.org/10.1007/978-1-4939-7128-2_19openalex-snapshot
Genome Editing of the Ascidian Ciona intestinalis with TALE Nuclease
inferred← citeshttps://doi.org/10.1007/978-3-319-26779-1_139-1openalex-snapshot
The Use of Electroporation in Developmental Biology
inferred← citeshttps://doi.org/10.1007/978-3-319-26779-1_139-2openalex-snapshot
The Use of Electroporation in Developmental Biology
inferred← citeshttps://doi.org/10.1007/978-3-319-32886-7_139openalex-snapshot
The Use of Electroporation in Developmental Biology
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Aquatic Model Organisms in Neurosciences: The Genome-Editing Revolution
inferred← citeshttps://doi.org/10.1007/978-3-319-92486-1_16openalex-snapshot
Whole-Body Regeneration in the Colonial Tunicate Botrylloides leachii
inferred← citeshttps://doi.org/10.1007/978-3-319-92486-1_9openalex-snapshot
The Ciona Notochord Gene Regulatory Network
inferred← citeshttps://doi.org/10.1007/978-981-10-7545-2_13openalex-snapshot
CRISPR Knockouts in Ciona Embryos
inferred← citeshttps://doi.org/10.1007/978-981-10-7545-2_14openalex-snapshot
Transgenic Techniques for Investigating Cell Biology During Development
inferred← citeshttps://doi.org/10.1007/978-981-10-7545-2_16openalex-snapshot
Morphology and Physiology of the Ascidian Nervous Systems and the Effectors
inferred← citeshttps://doi.org/10.1007/978-981-10-7545-2_6openalex-snapshot
The Use of cis-Regulatory DNAs as Molecular Tools
inferred← citeshttps://doi.org/10.1007/978-981-10-7545-2_8openalex-snapshot
Investigating Evolutionarily Conserved Molecular Mechanisms Controlling Gene Expression in the Notochord
inferred← citeshttps://doi.org/10.1007/978-981-10-7545-2_9openalex-snapshot
Purification of Fluorescent Labeled Cells from Dissociated Ciona Embryos
inferred← citeshttps://doi.org/10.1007/s10750-018-3854-yopenalex-snapshot
Targeted cytochrome P450 3045C1 (CYP3045C1) gene mutation via CRISPR-Cas9 ribonucleoproteins in the marine rotifer Brachionus koreanus
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Biodiversity-based development and evolution: the emerging research systems in model and non-model organisms
inferred← citeshttps://doi.org/10.1007/s42995-019-00011-4openalex-snapshot
Delivery methods for CRISPR/Cas9 gene editing in crustaceans
inferred← citeshttps://doi.org/10.1007/s42995-023-00200-2openalex-snapshot
Establishment of a developmental atlas and transgenetic tools in the ascidian Styela clava
inferred← citeshttps://doi.org/10.1007/s42995-025-00300-1openalex-snapshot
Development of cell labeling and gene editing tools in urochordate Ciona
inferred← citeshttps://doi.org/10.1016/b978-0-12-809633-8.12148-xopenalex-snapshot
Heart Development in Ciona
inferred← citeshttps://doi.org/10.1016/b978-0-443-34262-2.00007-5openalex-snapshot
Genetic engineering for designer eggs production
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2020.01.002openalex-snapshot
The notochord gene regulatory network in chordate evolution: Conservation and divergence from Ciona to vertebrates
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2016.06.009openalex-snapshot
Insert, remove or replace: A highly advanced genome editing system using CRISPR/Cas9
inferred← citeshttps://doi.org/10.1016/j.celrep.2015.09.035openalex-snapshot
T-type Calcium Channel Regulation of Neural Tube Closure and EphrinA/EPHA Expression
inferred← citeshttps://doi.org/10.1016/j.celrep.2025.115578openalex-snapshot
Anoctamins mediate polymodal sensory perception and larval metamorphosis in a non-vertebrate chordate
inferred← citeshttps://doi.org/10.1016/j.cels.2020.11.001openalex-snapshot
Conserved Epigenetic Regulatory Logic Infers Genes Governing Cell Identity
inferred← citeshttps://doi.org/10.1016/j.cub.2018.08.048openalex-snapshot
Prevalence of Mutation-Prone Microhomology-Mediated End Joining in a Chordate Lacking the c-NHEJ DNA Repair Pathway
inferred← citeshttps://doi.org/10.1016/j.devcel.2015.07.001openalex-snapshot
Mitotic Membrane Turnover Coordinates Differential Induction of the Heart Progenitor Lineage
inferred← citeshttps://doi.org/10.1016/j.diff.2026.100973openalex-snapshot
Validated CRISPR/Cas9 guide RNAs targeting neurodevelopmental genes in the tunicate Ciona robusta
inferred← citeshttps://doi.org/10.1016/j.gde.2015.02.008openalex-snapshot
Regulation and evolution of cardiopharyngeal cell identity and behavior: insights from simple chordates
inferred← citeshttps://doi.org/10.1016/j.ibmb.2021.103705openalex-snapshot
Insights into gene manipulation techniques for Acari functional genomics
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Spermatogenic Cell-Specific Gene Mutation in Mice via CRISPR-Cas9
inferred← citeshttps://doi.org/10.1016/j.jglr.2020.03.010openalex-snapshot
Applying functional genomics to the study of lamprey development and sea lamprey population control
inferred← citeshttps://doi.org/10.1016/j.margen.2016.10.003openalex-snapshot
Diving into marine genomics with CRISPR/Cas9 systems
inferred← citeshttps://doi.org/10.1016/j.mce.2023.112122openalex-snapshot
The neuroendocrine system of Ciona intestinalis Type A, a deuterostome invertebrate and the closest relative of vertebrates
inferred← citeshttps://doi.org/10.1016/j.semcdb.2016.06.015openalex-snapshot
Photoperiodic regulation of behavior: Peromyscus as a model system
inferred← citeshttps://doi.org/10.1016/j.stem.2016.11.006openalex-snapshot
A Multi-step Transcriptional and Chromatin State Cascade Underlies Motor Neuron Programming from Embryonic Stem Cells
inferred← citeshttps://doi.org/10.1016/j.stem.2020.12.009openalex-snapshot
Histone crotonylation promotes mesoendodermal commitment of human embryonic stem cells
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Emerging from the bottleneck: benefits of the comparative approach to modern neuroscience
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A pipeline for the systematic identification of non-redundant full-ORF cDNAs for polymorphic and evolutionary divergent genomes: Application to the ascidian Ciona intestinalis
inferred← citeshttps://doi.org/10.1016/j.ydbio.2017.01.022openalex-snapshot
Germ cell regeneration-mediated, enhanced mutagenesis in the ascidian Ciona intestinalis reveals flexible germ cell formation from different somatic cells
inferred← citeshttps://doi.org/10.1016/j.ydbio.2017.03.003openalex-snapshot
Evaluation and rational design of guide RNAs for efficient CRISPR/Cas9-mediated mutagenesis in Ciona
inferred← citeshttps://doi.org/10.1016/j.ydbio.2017.08.036openalex-snapshot
Optimization of CRISPR/Cas9 genome editing for loss-of-function in the early chick embryo
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EvoRegen in animals: Time to uncover deep conservation or convergence of adult stem cell evolution and regenerative processes
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Papillae revisited and the nature of the adhesive secreting collocytes
inferred← citeshttps://doi.org/10.1016/j.ydbio.2018.12.018openalex-snapshot
Initial characterization of Wnt-Tcf functions during Ciona heart development
inferred← citeshttps://doi.org/10.1016/j.ydbio.2019.10.012openalex-snapshot
Effector gene expression underlying neuron subtype-specific traits in the Motor Ganglion of Ciona
inferred← citeshttps://doi.org/10.1016/j.ydbio.2019.10.028openalex-snapshot
Hox13 is essential for formation of a sensory organ at the terminal end of the sperm duct in Ciona
inferred← citeshttps://doi.org/10.1016/j.ydbio.2021.08.006openalex-snapshot
Misregulation of cell adhesion molecules in the Ciona neural tube closure mutant bugeye
inferred← citeshttps://doi.org/10.1016/j.ydbio.2024.03.003openalex-snapshot
Optimizing CRISPR/Cas9 approaches in the polymorphic tunicate Ciona intestinalis
inferred← citeshttps://doi.org/10.1016/j.ydbio.2025.03.007openalex-snapshot
A gene regulatory network for specification and morphogenesis of a Mauthner Cell homolog in non-vertebrate chordates
inferred← citeshttps://doi.org/10.1016/j.ydbio.2025.08.013openalex-snapshot
Germ cell formation and reproduction in tunicates
inferred← citeshttps://doi.org/10.1038/s41467-018-07976-3openalex-snapshot
Discoidin-domain receptor coordinates cell-matrix adhesion and collective polarity in migratory cardiopharyngeal progenitors
inferred← citeshttps://doi.org/10.1038/s41467-024-46850-3openalex-snapshot
Cis-regulatory interfaces reveal the molecular mechanisms underlying the notochord gene regulatory network of Ciona
inferred← citeshttps://doi.org/10.1038/s41556-019-0336-zopenalex-snapshot
A single-cell transcriptional roadmap for cardiopharyngeal fate diversification
inferred← citeshttps://doi.org/10.1038/s41586-022-04742-wopenalex-snapshot
Hmx gene conservation identifies the origin of vertebrate cranial ganglia
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The tunicate Ciona
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Automated behavioural analysis reveals the basic behavioural repertoire of the urochordate Ciona intestinalis
inferred← citeshttps://doi.org/10.1038/s44318-025-00613-yopenalex-snapshot
Cell cycle-driven transcriptome maturation confers multilineage competence to cardiopharyngeal progenitors
inferred← citeshttps://doi.org/10.1073/pnas.2309989120openalex-snapshot
Cereblon influences the timing of muscle differentiation in Ciona tadpoles
inferred← citeshttps://doi.org/10.1093/bfgp/elw038openalex-snapshot
Molecular basis, applications and challenges of CRISPR/Cas9: a continuously evolving tool for genome editing
inferred← citeshttps://doi.org/10.1093/database/bav055openalex-snapshot
CrisprGE: a central hub of CRISPR/Cas-based genome editing
inferred← citeshttps://doi.org/10.1093/icb/icad071openalex-snapshot
Loss of collagen gene expression in the notochord of the tailless tunicate Molgula occulta
inferred← citeshttps://doi.org/10.1093/icb/icae108openalex-snapshot
CRISPR/Cas9 Protocols for Disrupting Gene Function in the Non-vertebrate Chordate Ciona
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Inference of Developmental Gene Regulatory Networks Beyond Classical Model Systems: New Approaches in the Post-genomic Era
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ANISEED 2015: a digital framework for the comparative developmental biology of ascidians
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ANISEED 2017: extending the integrated ascidian database to the exploration and evolutionary comparison of genome-scale datasets
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Tunicates: exploring the sea shores and roaming the open ocean. A tribute to Thomas Huxley
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A simple inland culture system provides insights into ascidian post-embryonic developmental physiology
inferred← citeshttps://doi.org/10.1101/138701openalex-snapshot
An FGF-driven feed-forward circuit patterns the cardiopharyngeal mesoderm in space and time
inferred← citeshttps://doi.org/10.1101/154880openalex-snapshot
Dual functions of Discoidin domain receptor coordinate cell-matrix adhesion and collective polarity in migratory cardiopharyngeal progenitors
inferred← citeshttps://doi.org/10.1101/2020.10.16.342535openalex-snapshot
Mapping calcium dynamics in a developing tubular structure
inferred← citeshttps://doi.org/10.1101/2022.01.07.475354openalex-snapshot
Rnf149-related is an FGF/MAPK-independent regulator of pharyngeal muscle fate specification
inferred← citeshttps://doi.org/10.1101/2023.01.20.524945openalex-snapshot
Anoctamin 10/TMEM16K mediates convergent extension and tubulogenesis during notochord formation in the early chordate Ciona intestinalis
inferred← citeshttps://doi.org/10.1101/2023.05.02.539060openalex-snapshot
Specification of distinct cell types in a sensory-adhesive organ for metamorphosis in the Ciona larva
inferred← citeshttps://doi.org/10.1101/2023.06.16.545305openalex-snapshot
Specification and survival of post-metamorphic branchiomeric neurons in the hindbrain of a non-vertebrate chordate
inferred← citeshttps://doi.org/10.1101/2024.07.05.602308openalex-snapshot
A conserved RNA switch for acetylcholine receptor clustering at neuromuscular junctions in chordates
inferred← citeshttps://doi.org/10.1101/2025.07.11.664433openalex-snapshot
A protocadherin mediates cell-cell adhesion and integrity of the oral placode in the tunicate Ciona
inferred← citeshttps://doi.org/10.1101/567719openalex-snapshot
A cis-regulatory change underlying the motor neuron-specific loss of terminal selector gene expression in immotile tunicate larvae
inferred← citeshttps://doi.org/10.1111/dgd.70028openalex-snapshot
Hox3 Is Required for Post‐Metamorphic Heart Development in Adult Ciona
inferred← citeshttps://doi.org/10.1111/ede.12364openalex-snapshot
A cis‐regulatory change underlying the motor neuron‐specific loss of Ebf expression in immotile tunicate larvae
inferred← citeshttps://doi.org/10.1111/eva.13456openalex-snapshot
Marine animal evolutionary developmental biology—Advances through technology development
inferred← citeshttps://doi.org/10.1126/sciadv.abg0834openalex-snapshot
GATA4/5/6 family transcription factors are conserved determinants of cardiac versus pharyngeal mesoderm fate
inferred← citeshttps://doi.org/10.1126/sciadv.add2696openalex-snapshot
Evolution of a chordate-specific mechanism for myoblast fusion
inferred← citeshttps://doi.org/10.1126/sciadv.aeb8106openalex-snapshot
A thyroid hormone–mediated opsin switch initiates metamorphosis in a proto-vertebrate
inferred← citeshttps://doi.org/10.1139/cjz-2022-0213openalex-snapshot
Neuroendocrinology of the vase tunicate, Ciona intestinalis: consideration of the practical applications for the control of this invasive species
inferred← citeshttps://doi.org/10.1186/s12915-022-01355-7openalex-snapshot
Highly distinct genetic programs for peripheral nervous system formation in chordates
inferred← citeshttps://doi.org/10.1186/s13227-016-0056-4openalex-snapshot
Fibronectin contributes to notochord intercalation in the invertebrate chordate, Ciona intestinalis
inferred← citeshttps://doi.org/10.1242/bio.024786openalex-snapshot
Proteomic responses to elevated ocean temperature in ovaries of the ascidian Ciona intestinalis
inferred← citeshttps://doi.org/10.1242/bio.060002openalex-snapshot
Using CRISPR/Cas9 to identify genes required for mechanosensory neuron development and function
inferred← citeshttps://doi.org/10.1242/bio.062169openalex-snapshot
A protocadherin mediates oral placode morphogenesis in the tunicate Ciona
inferred← citeshttps://doi.org/10.1242/dev.134809openalex-snapshot
Maximizing mutagenesis with solubilized CRISPR-Cas9 ribonucleoprotein complexes.
inferred← citeshttps://doi.org/10.1242/dev.136267openalex-snapshot
Rewiring of an ancestral Tbx1/10-Ebf-Mrf network for pharyngeal muscle specification in distinct embryonic lineages
inferred← citeshttps://doi.org/10.1242/dev.193565openalex-snapshot
A single-plasmid approach for genome editing coupled with long-term lineage analysis in chick embryos
inferred← citeshttps://doi.org/10.1242/dev.201275openalex-snapshot
Aquaporin regulates cell rounding through vacuole formation during endothelial-to-hematopoietic transition
inferred← citeshttps://doi.org/10.1242/dev.202719openalex-snapshot
Specification and survival of post-metamorphic branchiomeric neurons in a non-vertebrate chordate
inferred← citeshttps://doi.org/10.1242/dev.202968openalex-snapshot
A change in cis-regulatory logic underlying obligate versus facultative muscle multinucleation in chordates
inferred← citeshttps://doi.org/10.1242/dev.205088openalex-snapshot
In preprints: it takes nerves to grow a heart
inferred← citeshttps://doi.org/10.1242/jeb.208793openalex-snapshot
Bringing immersive science to undergraduate laboratory courses using CRISPR gene knockouts in frogs and butterflies
inferred← citeshttps://doi.org/10.1371/journal.pbio.3002169openalex-snapshot
Lhx3/4 initiates a cardiopharyngeal-specific transcriptional program in response to widespread FGF signaling
inferred← citeshttps://doi.org/10.1371/journal.pbio.3002555openalex-snapshot
Specification of distinct cell types in a sensory-adhesive organ important for metamorphosis in tunicate larvae
inferred← citeshttps://doi.org/10.1371/journal.pbio.3002762openalex-snapshot
The ion channel Anoctamin 10/TMEM16K coordinates organ morphogenesis across scales in the urochordate notochord
inferred← citeshttps://doi.org/10.1371/journal.pbio.3003392openalex-snapshot
Neuron-specific Agrin splicing by Nova RNA-binding proteins regulates conserved neuromuscular junction development in chordates
inferred← citeshttps://doi.org/10.1371/journal.pbio.3003715openalex-snapshot
Neural signaling contributes to heart formation and growth in the invertebrate chordate, Ciona robusta
inferred← citeshttps://doi.org/10.1371/journal.pgen.1008054openalex-snapshot
Antero-posterior ectoderm patterning by canonical Wnt signaling during ascidian development
inferred← citeshttps://doi.org/10.1371/journal.pgen.1012334openalex-snapshot
An NKX2-3/5/6 homolog is required downstream of BMP signaling to pattern the sensory-adhesive organ of a tunicate larva
inferred← citeshttps://doi.org/10.1590/0001-3765201520140710openalex-snapshot
From Gene Targeting to Genome Editing: Transgenic animals applications and beyond
inferred← citeshttps://doi.org/10.18297/etd/3496openalex-snapshot
Comparative secretomics and functional analysis of effectors utilized by the Microbotryum genus of anther-smut fungal pathogens, and their role in host-specificity.
inferred← citeshttps://doi.org/10.21203/rs.3.rs-6313466/v1openalex-snapshot
Repressive Roles of Erf and Elk in FGF-Regulated Neural Development in Ciona intestinalis
inferred← citeshttps://doi.org/10.3389/fcell.2020.00477openalex-snapshot
Regulation of Neurogenesis by FGF Signaling and Neurogenin in the Invertebrate Chordate Ciona
inferred← citeshttps://doi.org/10.3389/fcell.2020.569601openalex-snapshot
The Cis-Regulatory Code for Kelch-like 21/30 Specific Expression in Ciona robusta Sensory Organs
inferred← citeshttps://doi.org/10.3389/fcell.2021.701779openalex-snapshot
Brain Sensory Organs of the Ascidian Ciona robusta: Structure, Function and Developmental Mechanisms
inferred← citeshttps://doi.org/10.3389/fcell.2021.804032openalex-snapshot
Quantitative Dissection of the Proximal Ciona brachyury Enhancer
inferred← citeshttps://doi.org/10.3389/fcell.2022.750833openalex-snapshot
Efficient CRISPR Mutagenesis in Sturgeon Demonstrates Its Utility in Large, Slow-Maturing Vertebrates
inferred← citeshttps://doi.org/10.3389/fcell.2022.999511openalex-snapshot
Pax3/7 regulates neural tube closure and patterning in a non-vertebrate chordate
inferred← citeshttps://doi.org/10.3389/fcell.2024.1414759openalex-snapshot
Stress granule-related genes during embryogenesis of an invertebrate chordate
inferred← citeshttps://doi.org/10.3389/fevo.2024.1385516openalex-snapshot
Matrix metalloproteinase Nas15 regulates the lumen formation and expansion in Ciona notochord
inferred← citeshttps://doi.org/10.3389/fnins.2021.784649openalex-snapshot
Ebf Activates Expression of a Cholinergic Locus in a Multipolar Motor Ganglion Interneuron Subtype in Ciona
inferred← citeshttps://doi.org/10.3390/genes12030406openalex-snapshot
MiR-92 Family Members Form a Cluster Required for Notochord Tubulogenesis in Urochordate Ciona savignyi
inferred← citeshttps://doi.org/10.3390/ijms20205127openalex-snapshot
miR-7 Knockdown by Peptide Nucleic Acids in the Ascidian Ciona intestinalis
inferred← citeshttps://doi.org/10.3390/ijms232214407openalex-snapshot
Nuclear Factor of Activated T Cells-5 Regulates Notochord Lumenogenesis in Chordate Larval Development
inferred← citeshttps://doi.org/10.3390/ijms24108865openalex-snapshot
Ring Finger 149-Related Is an FGF/MAPK-Independent Regulator of Pharyngeal Muscle Fate Specification
inferred← citeshttps://doi.org/10.3390/ijms25052793openalex-snapshot
Dynamics of Chromatin Opening across Larval Development in the Urochordate Ascidian Ciona savignyi
inferred← citeshttps://doi.org/10.3390/ijms25063413openalex-snapshot
Snail Transcriptionally Represses Brachyury to Promote the Mesenchymal-Epithelial Transition in Ascidian Notochord Cells
inferred← citeshttps://doi.org/10.3390/jcdd3030025openalex-snapshot
Ciona as a Simple Chordate Model for Heart Development and Regeneration
inferred← citeshttps://doi.org/10.3390/microorganisms12010118openalex-snapshot
Clustered Regularly Interspaced Short Palindromic Repeat/CRISPR-Associated Protein and Its Utility All at Sea: Status, Challenges, and Prospects
inferred← citeshttps://doi.org/10.3791/54313openalex-snapshot
Embryo Microinjection and Electroporation in the Chordate Ciona intestinalis
inferred← citeshttps://doi.org/10.4137/ebo.s37920openalex-snapshot
The Simple Chordate Ciona intestinalis Has a Reduced Complement of Genes Associated with Fanconi Anemia
inferred← citeshttps://doi.org/10.64898/2025.12.18.695272openalex-snapshot
An NKX2-5 homolog is required downstream of BMP signaling to pattern the sensory-adhesive organ of a tunicate larva
inferred← citeshttps://doi.org/10.64898/2026.03.04.709676openalex-snapshot
Temporal Gatekeeping Role of Lmx1 during chordate neural tube morphogenesis
inferred← citeshttps://doi.org/10.70675/4e7c6892z5caaz4f0bza17bz4fdc4b3bb7ecopenalex-snapshot
Conception and fabrication of reusable microfluidic tools to study the dynamics of biological phenomena : application to antibiotic influx/efflux in bacteria and to cell migration during mouse development
inferred← citeshttps://doi.org/10.70675/594fda00z839ez49c6zb265z45ff8b8032ccopenalex-snapshot
Caractérisation de la voie de l’autophagie chez l’huître creuse Crassostrea gigas en réponse à une infection par le virus OsHV-1
inferred← citeshttps://doi.org/10.70675/59604ff1z809az4462zb8f9z6a8870b33001openalex-snapshot
Signatures nucléotidiques de l'activité des enhancers développementaux chez l'ascidie Ciona intestinalis
inferred← citeshttps://doi.org/10.70675/6da04ca8z76d8z4fd4z9f55zde97179c8e99openalex-snapshot
Evolution of regulation of ascidian species
inferred← citeshttps://doi.org/10.70675/88022c7cz3024z45c3zb8cfz1146d23fc399openalex-snapshot
Formation du système nerveux périphérique ventral chez l'ascidie et l'amphioxus : aperçu de son origine au sein des chordés
inferred← citeshttps://doi.org/10.70675/c94fdd4cz73bez40cezb5a2zd71a6afdee58openalex-snapshot
Effets des perturbateurs endocriniens sur le développement embryonnaire de Phallusia mammillata
inferred← citeshttps://doi.org/10.7554/elife.29656openalex-snapshot
An FGF-driven feed-forward circuit patterns the cardiopharyngeal mesoderm in space and time
inferred← citeshttps://doi.org/10.7554/elife.49921openalex-snapshot
Combinatorial chromatin dynamics foster accurate cardiopharyngeal fate choices
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