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ErbB and HB-EGF Signaling in Heart Development and Function

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/(sici)1097-0185(20000201)258:2<119::aid-ar1>3.0.co;2-uopenalex-snapshot
Mechanisms involved in valvuloseptal endocardial cushion formation in early cardiogenesis: Roles of transforming growth factor (TGF)-β and bone morphogenetic protein (BMP)
inferredcites →https://doi.org/10.1002/(sici)1521-1878(199801)20:1<41::aid-bies7>3.0.co;2-vopenalex-snapshot
Specificity within the EGF family/ErbB receptor family signaling network
inferredcites →https://doi.org/10.1002/j.1460-2075.1994.tb06516.xopenalex-snapshot
Heparin‐binding EGF‐like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up‐regulates functional receptors and diphtheria toxin sensitivity.
inferredcites →https://doi.org/10.1006/dbio.2001.0284openalex-snapshot
Bmp6 and Bmp7 Are Required for Cushion Formation and Septation in the Developing Mouse Heart
inferredcites →https://doi.org/10.1007/s00109-003-0456-5openalex-snapshot
Form and function of developing heart valves: coordination by extracellular matrix and growth factor signaling
inferredcites →https://doi.org/10.1016/0092-8674(92)90623-kopenalex-snapshot
Expression cloning of a diphtheria toxin receptor: Identity with a heparin-binding EGF-like growth factor precursor
inferredcites →https://doi.org/10.1016/0092-8674(93)90227-hopenalex-snapshot
Mice with a null mutation of the TGFα gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation
inferredcites →https://doi.org/10.1016/0092-8674(93)90228-iopenalex-snapshot
TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice
inferredcites →https://doi.org/10.1016/0167-5273(86)90201-9openalex-snapshot
Embryology of the mitral valve
inferredcites →https://doi.org/10.1016/j.bbr.2003.11.010openalex-snapshot
Behavioral characteristics of a nervous system-specific erbB4 knock-out mouse
inferredcites →https://doi.org/10.1016/j.cell.2004.08.010openalex-snapshot
A Field of Myocardial-Endocardial NFAT Signaling Underlies Heart Valve Morphogenesis
inferredcites →https://doi.org/10.1016/s0005-2728(97)00048-0openalex-snapshot
Determination of photochemical loss in leaves by an open-ended photothermal cell
inferredcites →https://doi.org/10.1016/s0012-1606(03)00099-xopenalex-snapshot
Fibroblast growth factor (FGF)-4 can induce proliferation of cardiac cushion mesenchymal cells during early valve leaflet formation
inferredcites →https://doi.org/10.1016/s0014-4827(02)00099-xopenalex-snapshot
The ErbB receptors and their role in cancer progression
inferredcites →https://doi.org/10.1016/s0021-9258(18)42682-8openalex-snapshot
Structure of heparin-binding EGF-like growth factor. Multiple forms, primary structure, and glycosylation of the mature protein.
inferredcites →https://doi.org/10.1016/s0092-8674(00)80729-1openalex-snapshot
Loss of a gp130 Cardiac Muscle Cell Survival Pathway Is a Critical Event in the Onset of Heart Failure during Biomechanical Stress
inferredcites →https://doi.org/10.1016/s0092-8674(01)00242-2openalex-snapshot
The Genetic Basis for Cardiomyopathy
inferredcites →https://doi.org/10.1016/s0092-8674(02)00834-6openalex-snapshot
Converging Pathways and Principles in Heart Development and Disease
inferredcites →https://doi.org/10.1016/s0092-8674(02)00969-8openalex-snapshot
Regulation of Myocardial Contractility and Cell Size by Distinct PI3K-PTEN Signaling Pathways
inferredcites →https://doi.org/10.1016/s0896-6273(00)80779-5openalex-snapshot
Rescue of the Cardiac Defect in ErbB2 Mutant Mice Reveals Essential Roles of ErbB2 in Peripheral Nervous System Development
inferredcites →https://doi.org/10.1016/s0896-6273(02)01128-5openalex-snapshot
Colonic Epithelial Expression of ErbB2 Is Required for Postnatal Maintenance of the Enteric Nervous System
inferredcites →https://doi.org/10.1016/s0925-4773(03)00068-6openalex-snapshot
Inhibition of zebrafish epidermal growth factor receptor activity results in cardiovascular defects
inferredcites →https://doi.org/10.1016/s0959-8049(01)00230-1openalex-snapshot
The EGFR family and its ligands in human cancer
inferredcites →https://doi.org/10.1016/s1359-6101(00)00013-7openalex-snapshot
Heparin-binding EGF-like growth factor: a juxtacrine growth factor
inferredcites →https://doi.org/10.1038/35052073openalex-snapshot
Untangling the ErbB signalling network
inferredcites →https://doi.org/10.1038/376337a0openalex-snapshot
Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor
inferredcites →https://doi.org/10.1038/378386a0openalex-snapshot
Multiple essential functions of neuregulin in development
inferredcites →https://doi.org/10.1038/378390a0openalex-snapshot
Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor
inferredcites →https://doi.org/10.1038/378394a0openalex-snapshot
Requirement for neuregulin receptor erbB2 in neural and cardiac development
inferredcites →https://doi.org/10.1038/39348openalex-snapshot
Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1
inferredcites →https://doi.org/10.1038/39593openalex-snapshot
Severe neuropathies in mice with targeted mutations in the ErbB3 receptor
inferredcites →https://doi.org/10.1038/415227aopenalex-snapshot
The failing heart
inferredcites →https://doi.org/10.1038/47260openalex-snapshot
EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
inferredcites →https://doi.org/10.1038/72835openalex-snapshot
A role for Smad6 in development and homeostasis of the cardiovascular system
inferredcites →https://doi.org/10.1038/73528openalex-snapshot
Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis
inferredcites →https://doi.org/10.1038/nature02028openalex-snapshot
The Wnt/β-catenin pathway regulates cardiac valve formation
inferredcites →https://doi.org/10.1038/nm0102-35openalex-snapshot
Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy
inferredcites →https://doi.org/10.1038/nm0102-41openalex-snapshot
Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells
inferredcites →https://doi.org/10.1038/nm0502-459openalex-snapshot
ErbB2 is essential in the prevention of dilated cardiomyopathy
inferredcites →https://doi.org/10.1038/nm719openalex-snapshot
Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy
inferredcites →https://doi.org/10.1038/nm742openalex-snapshot
Heart-valve mesenchyme formation is dependent on hyaluronan-augmented activation of ErbB2–ErbB3 receptors
inferredcites →https://doi.org/10.1042/bj3340189openalex-snapshot
Signal transduction by epidermal growth factor and heregulin via the kinase-deficient ErbB3 protein
inferredcites →https://doi.org/10.1053/gast.2001.25478openalex-snapshot
Growth Retardation, Duodenal Lesions, and Aberrant Ileum Architecture in Triple Null Mice Lacking EGF, Amphiregulin, and TGF-α
inferredcites →https://doi.org/10.1056/nejm200103153441101openalex-snapshot
Use of Chemotherapy plus a Monoclonal Antibody against HER2 for Metastatic Breast Cancer That Overexpresses HER2
inferredcites →https://doi.org/10.1073/pnas.0404217101openalex-snapshot
Dermatitis due to epiregulin deficiency and a critical role of epiregulin in immune-related responses of keratinocyte and macrophage
inferredcites →https://doi.org/10.1073/pnas.0537588100openalex-snapshot
Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function
inferredcites →https://doi.org/10.1073/pnas.122249299openalex-snapshot
Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy
inferredcites →https://doi.org/10.1073/pnas.1436402100openalex-snapshot
Neural and mammary gland defects in ErbB4 knockout mice genetically rescued from embryonic lethality
inferredcites →https://doi.org/10.1073/pnas.90.9.3889openalex-snapshot
Appearance of heparin-binding EGF-like growth factor in wound fluid as a response to injury.
inferredcites →https://doi.org/10.1073/pnas.91.17.8132openalex-snapshot
Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity.
inferredcites →https://doi.org/10.1073/pnas.91.25.12173openalex-snapshot
Heparin-dependent binding and autophosphorylation of epidermal growth factor (EGF) receptor by heparin-binding EGF-like growth factor but not by EGF.
inferredcites →https://doi.org/10.1073/pnas.96.10.5716openalex-snapshot
Heparin-binding epidermal growth factor-like growth factor, a v-Jun target gene, induces oncogenic transformation
inferredcites →https://doi.org/10.1074/jbc.270.41.24604openalex-snapshot
Binding of Neu Differentiation Factor with the Extracellular Domain of Her2 and Her3
inferredcites →https://doi.org/10.1074/jbc.270.49.29578openalex-snapshot
Heparin-like Molecules on the Cell Surface Potentiate Binding of Diphtheria Toxin to the Diphtheria Toxin Receptor/Membrane-anchored Heparin-binding Epidermal Growth Factor-like Growth Factor
inferredcites →https://doi.org/10.1074/jbc.273.51.34063openalex-snapshot
Acute Suppression of Inwardly Rectifying Kir2.1 Channels by Direct Tyrosine Kinase Phosphorylation
inferredcites →https://doi.org/10.1074/jbc.274.23.16168openalex-snapshot
Ca2+/Calmodulin-dependent Kinase II Phosphorylates the Epidermal Growth Factor Receptor on Multiple Sites in the Cytoplasmic Tail and Serine 744 within the Kinase Domain to Regulate Signal Generation
inferredcites →https://doi.org/10.1074/jbc.274.36.25906openalex-snapshot
Contact-dependent Growth Inhibition and Apoptosis of Epidermal Growth Factor (EGF) Receptor-expressing Cells by the Membrane-anchored Form of Heparin-binding EGF-like Growth Factor
inferredcites →https://doi.org/10.1074/jbc.m008570200openalex-snapshot
Activation of MAPKs by Angiotensin II in Vascular Smooth Muscle Cells
inferredcites →https://doi.org/10.1074/jbc.m103673200openalex-snapshot
A Dual Signaling Cascade That Regulates the Ectodomain Shedding of Heparin-binding Epidermal Growth Factor-like Growth Factor
inferredcites →https://doi.org/10.1074/jbc.m108525200openalex-snapshot
The Cardiac-specific Nuclear δB Isoform of Ca2+/Calmodulin-dependent Protein Kinase II Induces Hypertrophy and Dilated Cardiomyopathy Associated with Increased Protein Phosphatase 2A Activity
inferredcites →https://doi.org/10.1074/jbc.m211835200openalex-snapshot
The Stress- and Inflammatory Cytokine-induced Ectodomain Shedding of Heparin-binding Epidermal Growth Factor-like Growth Factor Is Mediated by p38 MAPK, Distinct from the 12-O-Tetradecanoylphorbol-13-acetate- and Lysophosphatidic Acid-induced Signaling Cascades
inferredcites →https://doi.org/10.1074/jbc.m408556200openalex-snapshot
Suppression of the Biological Activities of the Epidermal Growth Factor (EGF)-like Domain by the Heparin-binding Domain of Heparin-binding EGF-like Growth Factor
inferredcites →https://doi.org/10.1083/jcb.122.4.933openalex-snapshot
Heparin-binding EGF-like growth factor stimulation of smooth muscle cell migration: dependence on interactions with cell surface heparan sulfate
inferredcites →https://doi.org/10.1083/jcb.128.5.929openalex-snapshot
The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor.
inferredcites →https://doi.org/10.1083/jcb.129.6.1691openalex-snapshot
Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptor-associated protein (DRAP27)/CD9 form a complex with integrin alpha 3 beta 1 at cell-cell contact sites.
inferredcites →https://doi.org/10.1083/jcb.141.3.715openalex-snapshot
Agrin Can Mediate Acetylcholine Receptor Gene Expression in Muscle by Aggregation of Muscle-derived Neuregulins
inferredcites →https://doi.org/10.1083/jcb.151.2.209openalex-snapshot
Ectodomain Shedding of Epidermal Growth Factor Receptor Ligands Is Required for Keratinocyte Migration in Cutaneous Wound Healing
inferredcites →https://doi.org/10.1083/jcb.200307035openalex-snapshot
Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities
inferredcites →https://doi.org/10.1083/jcb.200307137openalex-snapshot
Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands
inferredcites →https://doi.org/10.1091/mbc.6.8.967openalex-snapshot
Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: conversion from juxtacrine to paracrine growth factor activity.
inferredcites →https://doi.org/10.1093/emboj/16.6.1268openalex-snapshot
Activation of HER4 by heparin‐binding EGF‐like growth factor stimulates chemotaxis but not proliferation
inferredcites →https://doi.org/10.1093/emboj/16.7.1647openalex-snapshot
ErbB‐2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
inferredcites →https://doi.org/10.1093/emboj/17.24.7260openalex-snapshot
A metalloprotease–disintegrin, MDC9/meltrin‐γ/ADAM9 and PKCδ are involved in TPA‐induced ectodomain shedding of membrane‐anchored heparin‐binding EGF‐like growth factor
inferredcites →https://doi.org/10.1093/emboj/19.13.3159openalex-snapshot
The ErbB signaling network: receptor heterodimerization in development and cancer
inferredcites →https://doi.org/10.1093/emboj/20.1.128openalex-snapshot
Epidermal growth factor signaling via Ras controls the Smad transcriptional co‐repressor TGIF
inferredcites →https://doi.org/10.1093/emboj/20.13.3342openalex-snapshot
N‐arginine dibasic convertase is a specific receptor for heparin‐binding EGF‐like growth factor that mediates cell migration
inferredcites →https://doi.org/10.1093/emboj/cdg264openalex-snapshot
Defective valvulogenesis in HB‐EGF and TACE‐null mice is associated with aberrant BMP signaling
inferredcites →https://doi.org/10.1101/gad.276304openalex-snapshot
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
inferredcites →https://doi.org/10.1126/science.1840698openalex-snapshot
A Heparin-Binding Growth Factor Secreted by Macrophage-Like Cells That Is Related to EGF
inferredcites →https://doi.org/10.1126/science.2181668openalex-snapshot
EGF Receptor and erb B-2 Tyrosine Kinase Domains Confer Cell Specificity for Mitogenic Signaling
inferredcites →https://doi.org/10.1126/science.7618084openalex-snapshot
Targeted Disruption of Mouse EGF receptor: Effect of Genetic Background on Mutant Phenotype
inferredcites →https://doi.org/10.1126/science.7618085openalex-snapshot
Strain-Dependent Epithelial Defects in Mice Lacking the EGF Receptor
inferredcites →https://doi.org/10.1128/mcb.16.10.5276openalex-snapshot
A Hierarchical Network of Interreceptor Interactions Determines Signal Transduction by Neu Differentiation Factor/Neuregulin and Epidermal Growth Factor
inferredcites →https://doi.org/10.1128/mcb.23.1.55-61.2003openalex-snapshot
Phenotypic Analysis of Meltrin α (ADAM12)-Deficient Mice: Involvement of Meltrin α in Adipogenesis and Myogenesis
inferredcites →https://doi.org/10.1128/mcb.24.18.8221-8226.2004openalex-snapshot
Generation and Characterization of Neuregulin-2-Deficient Mice
inferredcites →https://doi.org/10.1146/annurev.bi.62.070193.002503openalex-snapshot
MEMBRANE-ANCHORED GROWTH FACTORS
inferredcites →https://doi.org/10.1152/physrev.00017.2002openalex-snapshot
Cardiac Endothelial-Myocardial Signaling: Its Role in Cardiac Growth, Contractile Performance, and Rhythmicity
inferredcites →https://doi.org/10.1158/0008-5472.can-04-0811openalex-snapshot
Heparin-Binding EGF-Like Growth Factor Is a Promising Target for Ovarian Cancer Therapy
inferredcites →https://doi.org/10.1161/01.cir.100.23.2359openalex-snapshot
Dilated and Failing Cardiomyopathy in Bradykinin B2Receptor Knockout Mice
inferredcites →https://doi.org/10.1161/01.cir.103.24.2973openalex-snapshot
Ablation of Serotonin 5-HT2BReceptors in Mice Leads to Abnormal Cardiac Structure and Function
inferredcites →https://doi.org/10.1161/01.cir.91.1.111openalex-snapshot
Formation of the Tricuspid Valve in the Human Heart
inferredcites →https://doi.org/10.1161/01.res.0000141146.95728.daopenalex-snapshot
Heart Valve Development
inferredcites →https://doi.org/10.1161/01.res.77.1.1openalex-snapshot
Molecular Regulation of Atrioventricular Valvuloseptal Morphogenesis
inferredcites →https://doi.org/10.1172/jci10272openalex-snapshot
Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme
inferredcites →https://doi.org/10.1172/jci117669openalex-snapshot
Localization of heparin-binding EGF-like growth factor in the smooth muscle cells and macrophages of human atherosclerotic plaques.
inferredcites →https://doi.org/10.1242/dev.00181openalex-snapshot
BMP signaling is required for septation of the outflow tract of the mammalian heart
inferredcites →https://doi.org/10.1242/dev.00715openalex-snapshot
Impaired differentiation and lactational failure ofErbb4-deficient mammary glands identify ERBB4 as an obligate mediator of STAT5
inferredcites →https://doi.org/10.1242/dev.02030openalex-snapshot
HB-EGF promotes epithelial cell migration in eyelid development
inferredcites →https://doi.org/10.1242/dev.120.5.1071openalex-snapshot
Heparin-binding EGF-like growth factor gene is induced in the mouse uterus temporally by the blastocyst solely at the site of its apposition: a possible ligand for interaction with blastocyst EGF-receptor in implantation
inferredcites →https://doi.org/10.1242/dev.124.24.4999openalex-snapshot
ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2- and heregulin-deficient mice
inferredcites →https://doi.org/10.1242/dev.125.22.4359openalex-snapshot
Neurofibromin modulation of ras activity is required for normal endocardial-mesenchymal transformation in the developing heart
inferredcites →https://doi.org/10.1242/dev.126.12.2631openalex-snapshot
The mammalian Tolloid-like 1 gene, Tll1, is necessary for normal septation and positioning of the heart
inferredcites →https://doi.org/10.1242/dev.126.12.2739openalex-snapshot
Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development
inferredcites →https://doi.org/10.1242/jcs.02346openalex-snapshot
Heparin-binding EGF-like growth factor accelerates keratinocyte migration and skin wound healing
inferredcites →https://doi.org/10.1247/csf.30.35openalex-snapshot
Soluble Form of Heparin-binding EGF-like Growth Factor Contributes to Retinoic Acid-induced Epidermal Hyperplasia
inferredcites →https://doi.org/10.1387/ijdb.10707903openalex-snapshot
Convergence of the BMP and EGF signaling pathways on Smad1 in the regulation of chondrogenesis
inferredcites →https://doi.org/10.1523/jneurosci.18-02-00590.1998openalex-snapshot
Growth Factor Receptor Tyrosine Kinases Acutely Regulate Neuronal Sodium Channels through the Src Signaling Pathway
inferredcites →https://doi.org/10.1681/asn.v125964openalex-snapshot
Induction of Collecting Duct Morphogenesis In Vitro by Heparin-Binding Epidermal Growth Factor-Like Growth Factor
inferredcites →https://doi.org/10.32388/hz52weopenalex-snapshot
Heparin-Binding EGF-Like Growth Factor

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4781335openalex-extracted
The Abl1 Tyrosine Kinase and p53 are Key Players in Doxorubicin-Induced Cardiomyopathy and Their Cell Death Signaling Differs in Atrial and Ventricular Cardiomyocytes
inferred← citeshttps://doi.org/10.1002/cbin.10454openalex-snapshot
High‐level expression and purification of soluble bioactive recombinant human heparin‐binding epidermal growth factor in Escherichia coli
inferred← citeshttps://doi.org/10.1002/dvdy.21398openalex-snapshot
HB‐EGF decelerates cell proliferation synergistically with TGFα in perinatal distal lung development
inferred← citeshttps://doi.org/10.1002/jcb.25156openalex-snapshot
Systems Chemo‐Biology and Transcriptomic Meta‐Analysis Reveal the Molecular Roles of Bioactive Lipids in Cardiomyocyte Differentiation
inferred← citeshttps://doi.org/10.1002/phy2.224openalex-snapshot
MMP-1 and MMP-9 regulate epidermal growth factor-dependent collagen loss in human carotid plaque smooth muscle cells
inferred← citeshttps://doi.org/10.1002/wsbm.1329openalex-snapshot
Heart valve regeneration: the need for systems approaches
inferred← citeshttps://doi.org/10.1007/978-1-4419-9461-5_5openalex-snapshot
Growth Factors Signaling
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Reactivation of Epithelial-Mesenchymal Transition in Invasive and Metastatic Cancer
inferred← citeshttps://doi.org/10.1007/s00018-014-1795-9openalex-snapshot
EGF is required for cardiac differentiation of P19CL6 cells through interaction with GATA-4 in a time- and dose-dependent manner
inferred← citeshttps://doi.org/10.1007/s10439-017-1899-0openalex-snapshot
Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease
inferred← citeshttps://doi.org/10.1007/s10495-025-02222-wopenalex-snapshot
Signaling pathways and potential therapeutic agents in trastuzumab-induced cardiotoxicity
inferred← citeshttps://doi.org/10.1007/s10555-018-9746-9openalex-snapshot
Eicosanoids and HB-EGF/EGFR in cancer
inferred← citeshttps://doi.org/10.1007/s10911-010-9172-2openalex-snapshot
ErbB/EGF Signaling and EMT in Mammary Development and Breast Cancer
inferred← citeshttps://doi.org/10.1007/s12565-009-0027-0openalex-snapshot
Roles of TGFβ and BMP during valvulo–septal endocardial cushion formation
inferred← citeshttps://doi.org/10.1007/s13105-010-0009-7openalex-snapshot
Epidermal growth factor protects the heart against low-flow ischemia-induced injury
inferred← citeshttps://doi.org/10.1016/b978-0-12-381510-1.00009-0openalex-snapshot
Receptor Tyrosine Kinases in Cardiac Muscle
inferred← citeshttps://doi.org/10.1016/b978-0-12-394440-5.00012-7openalex-snapshot
Arrestins in the Cardiovascular System
inferred← citeshttps://doi.org/10.1016/b978-0-443-18677-6.00011-7openalex-snapshot
Receptor tyrosine kinases
inferred← citeshttps://doi.org/10.1016/j.amjms.2017.04.011openalex-snapshot
Overexpression of Heparin-Binding Epidermal Growth Factor-Like Growth Factor Mediates Liver Fibrosis in Transgenic Mice
inferred← citeshttps://doi.org/10.1016/j.bbaexp.2007.06.001openalex-snapshot
The Popdc gene family in the rat: Molecular cloning, characterization and expression analysis in the heart and cultured cardiomyocytes
inferred← citeshttps://doi.org/10.1016/j.bbrc.2006.07.129openalex-snapshot
Activity-dependent shedding of heparin-binding EGF-like growth factor in brain neurons
inferred← citeshttps://doi.org/10.1016/j.bbrc.2006.09.060openalex-snapshot
Loss of HB-EGF in smooth muscle or endothelial cell lineages causes heart malformation
inferred← citeshttps://doi.org/10.1016/j.bbrc.2013.05.097openalex-snapshot
Conditional loss of heparin-binding EGF-like growth factor results in enhanced liver fibrosis after bile duct ligation in mice
inferred← citeshttps://doi.org/10.1016/j.bcp.2023.115837openalex-snapshot
The role of EGFR in vascular AT1R signaling: From cellular mechanisms to systemic relevance
inferred← citeshttps://doi.org/10.1016/j.cca.2009.01.007openalex-snapshot
The role of ADAMs in disease pathophysiology
inferred← citeshttps://doi.org/10.1016/j.cjca.2013.04.026openalex-snapshot
Upregulation of Nox4 Promotes Angiotensin II-Induced Epidermal Growth Factor Receptor Activation and Subsequent Cardiac Hypertrophy by Increasing ADAM17 Expression
inferred← citeshttps://doi.org/10.1016/j.devcel.2009.01.020openalex-snapshot
Fibroblasts Inform the Heart: Control of Cardiomyocyte Cycling and Size by Age-Dependent Paracrine Signals
inferred← citeshttps://doi.org/10.1016/j.ejcts.2010.05.032openalex-snapshot
Environmental regulation of valvulogenesis: implications for tissue engineering
inferred← citeshttps://doi.org/10.1016/j.exer.2007.11.004openalex-snapshot
Presence of EGF growth factor ligands and their effects on cultured rat conjunctival goblet cell proliferation
inferred← citeshttps://doi.org/10.1016/j.jbiotec.2007.11.011openalex-snapshot
Cardiomyogenic gene expression profiling of differentiating human embryonic stem cells
inferred← citeshttps://doi.org/10.1016/j.mod.2013.01.001openalex-snapshot
Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults
inferred← citeshttps://doi.org/10.1016/j.mvr.2017.12.002openalex-snapshot
Important signals regulating coronary artery angiogenesis
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2008.11.008openalex-snapshot
Functional selectivity of EGF family peptide growth factors: Implications for cancer
inferred← citeshttps://doi.org/10.1016/j.phymed.2025.157357openalex-snapshot
Quercetin ameliorates doxorubicin-induced atrial fibrillation via EGFR-mediated restoration of autophagic flux
inferred← citeshttps://doi.org/10.1016/j.prp.2021.153721openalex-snapshot
Gene polymorphism in tissue epidermal growth factor receptor (EGFR) influences clinical and histological vulnerability of carotid plaques
inferred← citeshttps://doi.org/10.1016/j.semcdb.2014.03.004openalex-snapshot
Heparin-binding epidermal growth factor-like growth factor (HB-EGF) and proteolytic processing by a disintegrin and metalloproteinases (ADAM): A regulator of several pathways
inferred← citeshttps://doi.org/10.1016/j.taap.2013.11.006openalex-snapshot
Developmental defects in zebrafish for classification of EGF pathway inhibitors
inferred← citeshttps://doi.org/10.1016/j.ydbio.2006.09.051openalex-snapshot
lin-35/Rb and the CoREST ortholog spr-1 coordinately regulate vulval morphogenesis and gonad development in C. elegans
inferred← citeshttps://doi.org/10.1016/j.yexmp.2007.12.002openalex-snapshot
The status and role of ErbB receptors in human cancer
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2008.02.278openalex-snapshot
ErbB receptors, their ligands, and the consequences of their activation and inhibition in the myocardium
inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.7b01055openalex-snapshot
Systemic Administration of siRNA with Anti-HB-EGF Antibody-Modified Lipid Nanoparticles for the Treatment of Triple-Negative Breast Cancer
inferred← citeshttps://doi.org/10.1038/jid.2014.228openalex-snapshot
Exoming into Rare Skin Disease: EGFR Deficiency
inferred← citeshttps://doi.org/10.1038/s41572-019-0131-yopenalex-snapshot
Diphtheria
inferred← citeshttps://doi.org/10.1038/s41598-022-13911-wopenalex-snapshot
Mechanisms of Quercetin against atrial fibrillation explored by network pharmacology combined with molecular docking and experimental validation
inferred← citeshttps://doi.org/10.1038/srep07430openalex-snapshot
Moderate inappropriately high aldosterone/NaCl constellation in mice: cardiovascular effects and the role of cardiovascular epidermal growth factor receptor
inferred← citeshttps://doi.org/10.1042/cs20180842openalex-snapshot
Rare mutations of ADAM17 from TOFs induce hypertrophy in human embryonic stem cell-derived cardiomyocytes via HB-EGF signaling
inferred← citeshttps://doi.org/10.1073/pnas.0700901104openalex-snapshot
Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models
inferred← citeshttps://doi.org/10.1073/pnas.0702229104openalex-snapshot
Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7
inferred← citeshttps://doi.org/10.1073/pnas.2302937120openalex-snapshot
An unanticipated discourse of HB-EGF with VANGL2 signaling during embryo implantation
inferred← citeshttps://doi.org/10.1074/jbc.m109.020495openalex-snapshot
Negative Regulation of Stat3 by Activating PTPN11 Mutants Contributes to the Pathogenesis of Noonan Syndrome and Juvenile Myelomonocytic Leukemia
inferred← citeshttps://doi.org/10.1074/jbc.m110.205146openalex-snapshot
Endothelial Jarid2/Jumonji Is Required for Normal Cardiac Development and Proper Notch1 Expression
inferred← citeshttps://doi.org/10.1074/jbc.m608723200openalex-snapshot
Transient Suppression of Ligand-mediated Activation of Epidermal Growth Factor Receptor by Tumor Necrosis Factor-α through the TAK1-p38 Signaling Pathway
inferred← citeshttps://doi.org/10.1074/jbc.m610537200openalex-snapshot
A Novel Phosphoinositide 3-Kinase-dependent Pathway for Angiotensin II/AT-1 Receptor-mediated Induction of Collagen Synthesis in MES-13 Mesangial Cells
inferred← citeshttps://doi.org/10.1080/01902140802395757openalex-snapshot
ErbB4 REGULATES SURFACTANT SYNTHESIS AND PROLIFERATION IN ADULT RAT PULMONARY EPITHELIAL CELLS
inferred← citeshttps://doi.org/10.1080/08977190902913731openalex-snapshot
ErbB receptors protect the perfused heart against injury induced by epinephrine combined with low-flow ischemia
inferred← citeshttps://doi.org/10.1080/08977194.2020.1825410openalex-snapshot
Useful applications of growth factors for cardiovascular regenerative medicine
inferred← citeshttps://doi.org/10.1080/2162402x.2017.1287246openalex-snapshot
A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform
inferred← citeshttps://doi.org/10.1083/jcb.200607054openalex-snapshot
Defects in lamin B1 expression or processing affect interphase chromosome position and gene expression
inferred← citeshttps://doi.org/10.1089/cbr.2015.1956openalex-snapshot
Heparin-Binding Epidermal Growth Factor-Like Growth Factor as a Potent Target for Breast Cancer Therapy
inferred← citeshttps://doi.org/10.1089/dna.2007.0604openalex-snapshot
Changes in the Transcriptional Profile of Cardiac Myocytes Following Green Fluorescent Protein Expression
inferred← citeshttps://doi.org/10.1089/dna.2010.1024openalex-snapshot
Embryonic Survival and Severity of Cardiac and Craniofacial Defects Are Affected by Genetic Background in Fibroblast Growth Factor-16 Null Mice
inferred← citeshttps://doi.org/10.1093/abbs/gmq072openalex-snapshot
Computational analysis of microRNA function in heart development
inferred← citeshttps://doi.org/10.1093/biolre/ioy174openalex-snapshot
Extraembryonic heparin-binding epidermal growth factor-like growth factor deficiency compromises placentation in mice†
inferred← citeshttps://doi.org/10.1093/cvr/cvr281openalex-snapshot
Activation of epidermal growth factor receptor mediates reperfusion arrhythmias in anaesthetized rats
inferred← citeshttps://doi.org/10.1093/jb/mvm116openalex-snapshot
Diphtheria Toxin Mutant CRM197 Possesses Weak EF2-ADP-ribosyl Activity that Potentiates its Anti-tumorigenic Activity
inferred← citeshttps://doi.org/10.1093/jb/mvq033openalex-snapshot
Anti-human HB-EGF monoclonal antibodies inhibiting ectodomain shedding of HB-EGF and diphtheria toxin binding
inferred← citeshttps://doi.org/10.1093/jb/mvu079openalex-snapshot
Identification of diphtheria toxin R domain mutants with enhanced inhibitory activity against HB-EGF
inferred← citeshttps://doi.org/10.1093/jmcb/mjac059openalex-snapshot
The regenerative response of cardiac interstitial cells
inferred← citeshttps://doi.org/10.1093/med/9780198757269.003.0017openalex-snapshot
From cushions to leaflets: morphogenesis of cardiac atrioventricular valves
inferred← citeshttps://doi.org/10.1097/mao.0000000000000795openalex-snapshot
Heparin Binding Epidermal Growth Factor-Like Growth Factor Heals Chronic Tympanic Membrane Perforations With Advantage Over Fibroblast Growth Factor 2 and Epidermal Growth Factor in an Animal Model
inferred← citeshttps://doi.org/10.1101/2025.03.10.642402openalex-snapshot
EGFR-Mediated Mechanotransduction in Aortic Valve Cells: A Key Pathway in Response to Wall Shear Stress
inferred← citeshttps://doi.org/10.1101/cshperspect.a013912openalex-snapshot
How to Make a Heart Valve: From Embryonic Development to Bioengineering of Living Valve Substitutes
inferred← citeshttps://doi.org/10.1111/cpr.13179openalex-snapshot
ERp44 is required for endocardial cushion development by regulating VEGFA secretion in myocardium
inferred← citeshttps://doi.org/10.1111/eva.13090openalex-snapshot
Genomic adaptations to cereal‐based diets contribute to mitigate metabolic risk in some human populations of East Asian ancestry
inferred← citeshttps://doi.org/10.1111/febs.17033openalex-snapshot
HB‐EGF promotes progenitor cell proliferation and sensory neuron regeneration in the zebrafish olfactory epithelium
inferred← citeshttps://doi.org/10.1111/j.1349-7006.2007.00676.xopenalex-snapshot
Membrane‐anchored growth factors, the epidermal growth factor family: Beyond receptor ligands
inferred← citeshttps://doi.org/10.1111/j.1742-7843.2011.00686.xopenalex-snapshot
Regulation of Cigarette Smoke-Induced Mucin Expression by Neuregulin1β/ErbB3 Signalling in Human Airway Epithelial Cells
inferred← citeshttps://doi.org/10.1111/j.1755-5949.2012.00371.xopenalex-snapshot
Essential Roles of Heparin‐Binding Epidermal Growth Factor‐Like Growth Factor in the Brain
inferred← citeshttps://doi.org/10.1111/j.1872-034x.2012.01074.xopenalex-snapshot
Conditional knockout of heparin‐binding epidermal growth factor‐like growth factor in the liver accelerates carbon tetrachloride‐induced liver injury in mice
inferred← citeshttps://doi.org/10.1152/ajpheart.00063.2012openalex-snapshot
The role of neuregulin/ErbB2/ErbB4 signaling in the heart with special focus on effects on cardiomyocyte proliferation
inferred← citeshttps://doi.org/10.1152/ajpheart.91436.2007openalex-snapshot
Cardiac ErbB-1/ErbB-2 mutant expression in young adult mice leads to cardiac dysfunction
inferred← citeshttps://doi.org/10.1152/ajprenal.00345.2016openalex-snapshot
Can we fight chronic kidney disease by targeting endothelial HB-EGF?
inferred← citeshttps://doi.org/10.1155/2015/312848openalex-snapshot
Coronary Microvascular Function and Beyond: The Crosstalk between Hormones, Cytokines, and Neurotransmitters
inferred← citeshttps://doi.org/10.1158/1535-7163.mct-15-0741openalex-snapshot
Trastuzumab, but Not Pertuzumab, Dysregulates HER2 Signaling to Mediate Inhibition of Autophagy and Increase in Reactive Oxygen Species Production in Human Cardiomyocytes
inferred← citeshttps://doi.org/10.1161/circep.119.007212openalex-snapshot
EGF (Epidermal Growth Factor) Receptor Ligands in Atrial Fibrillation
inferred← citeshttps://doi.org/10.1161/circheartfailure.108.843722openalex-snapshot
A New Direction for Cardiac Regeneration Therapy
inferred← citeshttps://doi.org/10.1161/jaha.119.013452openalex-snapshot
Human CardioChimeras: Creation of a Novel “Next‐Generation” Cardiac Cell
inferred← citeshttps://doi.org/10.1167/iovs.08-1677openalex-snapshot
ERK/p44p42 Mitogen-Activated Protein Kinase Mediates EGF-Stimulated Proliferation of Conjunctival Goblet Cells in Culture
inferred← citeshttps://doi.org/10.1172/jci30651openalex-snapshot
Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling
inferred← citeshttps://doi.org/10.1186/1471-213x-8-75openalex-snapshot
Msx1 and Msx2are required for endothelial-mesenchymal transformation of the atrioventricular cushions and patterning of the atrioventricular myocardium
inferred← citeshttps://doi.org/10.1186/s12967-024-05623-8openalex-snapshot
The Abl1 tyrosine kinase is a key player in doxorubicin-induced cardiomyopathy and its p53/p73 cell death mediated signaling differs in atrial and ventricular cardiomyocytes
inferred← citeshttps://doi.org/10.1186/s13071-016-1921-7openalex-snapshot
Nutrigenomic effects of glucosinolates on liver, muscle and distal kidney in parasite-free and salmon louse infected Atlantic salmon
inferred← citeshttps://doi.org/10.1242/dev.048926openalex-snapshot
HB-EGF function in cardiac valve development requires interaction with heparan sulfate proteoglycans
inferred← citeshttps://doi.org/10.1242/dev.076398openalex-snapshot
Ectodomain shedding and ADAMs in development
inferred← citeshttps://doi.org/10.1242/dev.152710openalex-snapshot
ErbB1 and ErbB4 generate opposing signals regulating mesenchymal cell proliferation during valvulogenesis
inferred← citeshttps://doi.org/10.1242/dev.199900openalex-snapshot
Reciprocal EGFR signaling in the anchor cell ensures precise inter-organ connection during Caenorhabditis elegans vulval morphogenesis
inferred← citeshttps://doi.org/10.1242/dev.205065openalex-snapshot
Developmental single-cell atlas of coronary vessel growth and cardiomyocyte interaction in zebrafish
inferred← citeshttps://doi.org/10.1242/jcs.196618openalex-snapshot
ErbB1 and ErbB4 generate opposing signals regulating mesenchymal cell proliferation during valvulogenesis
inferred← citeshttps://doi.org/10.1247/csf.10001openalex-snapshot
Potential Involvement of Twist2 and Erk in the Regulation of Osteoblastogenesis by HB-EGF-EGFR Signaling
inferred← citeshttps://doi.org/10.12659/aot.937469openalex-snapshot
Network Pharmacology-Based Exploration of the Therapeutic Mechanisms of Cordyceps cicadae in Renal Ischemia/Reperfusion
inferred← citeshttps://doi.org/10.1371/journal.pntd.0014370openalex-snapshot
Plasma proteomics improves risk prediction in heart failure and reveals unique biology in chronic chagas cardiomyopathy
inferred← citeshttps://doi.org/10.1371/journal.pone.0012702openalex-snapshot
Regulation of Heparin-Binding EGF-Like Growth Factor by miR-212 and Acquired Cetuximab-Resistance in Head and Neck Squamous Cell Carcinoma
inferred← citeshttps://doi.org/10.1371/journal.pone.0027720openalex-snapshot
LIV-1 Promotes Prostate Cancer Epithelial-to-Mesenchymal Transition and Metastasis through HB-EGF Shedding and EGFR-Mediated ERK Signaling
inferred← citeshttps://doi.org/10.1371/journal.pone.0107411openalex-snapshot
Replication of the 4p16 Susceptibility Locus in Congenital Heart Disease in Han Chinese Populations
inferred← citeshttps://doi.org/10.1371/journal.pone.0144751openalex-snapshot
Amiodarone Induces Overexpression of Similar to Versican b to Repress the EGFR/Gsk3b/Snail Signaling Axis during Cardiac Valve Formation of Zebrafish Embryos
inferred← citeshttps://doi.org/10.1530/vb-20-0006openalex-snapshot
Angiogenesis and angiocrines regulating heart growth
inferred← citeshttps://doi.org/10.21203/rs.3.rs-1091154/v1openalex-snapshot
Exploring the Mechanism of Quercetin for the Treatment of Atrial Fibrillation by Geo Gene Chip Combined With Network Pharmacology and Molecular Docking
inferred← citeshttps://doi.org/10.21203/rs.3.rs-1229124/v1openalex-snapshot
Exploring the Mechanism of Quercetin for the Treatment of Atrial Fibrillation by GEO Gene Chip Combined with Network Pharmacology and Molecular Docking
inferred← citeshttps://doi.org/10.2217/14796694.2.6.765openalex-snapshot
Erbb Receptors and Epithelial-Cadherin–Catenin Complex In Human Carcinomas
inferred← citeshttps://doi.org/10.2527/jas.2011-4269openalex-snapshot
Microarray analysis reveals genes and functional networks relevant to the predisposition to inverted teats in pigs1
inferred← citeshttps://doi.org/10.25560/1300openalex-snapshot
Regulation of ATF3 expression in cardiomyocytes
inferred← citeshttps://doi.org/10.3109/00365521.2010.499960openalex-snapshot
Heparin-binding EGF-like factor augments esophageal epithelial cell proliferation, migration and inhibits TRAIL-mediated apoptosis via EGFR/MAPK signaling
inferred← citeshttps://doi.org/10.3109/08977190903443030openalex-snapshot
Heparin-binding EGF-like growth factor in human serum. Association with high blood cholesterol and heart hypertrophy
inferred← citeshttps://doi.org/10.33549/physiolres.935424openalex-snapshot
Novel Predictors of Preeclampsia and Pregnancy Complications: the Impact of Type 1 Diabetes Mellitus on Maternal and Fetal Circulatory Levels
inferred← citeshttps://doi.org/10.3389/fmolb.2023.1203208openalex-snapshot
Pharmacological effects and mechanisms of YiYiFuZi powder in chronic heart disease revealed by metabolomics and network pharmacology
inferred← citeshttps://doi.org/10.3390/ijms21134755openalex-snapshot
Eckol Alleviates Intestinal Dysfunction during Suckling-to-Weaning Transition via Modulation of PDX1 and HBEGF
inferred← citeshttps://doi.org/10.3390/ijms24129944openalex-snapshot
Molecular Mechanisms Driven by MT4-MMP in Cancer Progression
inferred← citeshttps://doi.org/10.3390/ijms242417287openalex-snapshot
Interaction between Selected Adipokines and Musculoskeletal and Cardiovascular Systems: A Review of Current Knowledge
inferred← citeshttps://doi.org/10.3390/toxins5061180openalex-snapshot
Heparin-Binding Epidermal Growth Factor-like Growth Factor/Diphtheria Toxin Receptor in Normal and Neoplastic Hematopoiesis
inferred← citeshttps://doi.org/10.4049/jimmunol.1301523openalex-snapshot
Preclinical In Vivo Modeling of Cytokine Release Syndrome Induced by ErbB-Retargeted Human T Cells: Identifying a Window of Therapeutic Opportunity?
inferred← citeshttps://doi.org/10.58088/0e74-d753openalex-snapshot
Transcriptome and histologic analysis of cardiac differences between modern broiler and heritage chickens
inferred← citeshttps://doi.org/10.64898/2026.05.26.26354173openalex-snapshot
ERBB4 deficiency promotes atrial myopathy underlying the atrial fibrillation substrate
inferred← citeshttps://doi.org/10.70675/a84ea862z9e21z4e2bza200za2d6a5f166b9openalex-snapshot
Metabolism, inflammation, and mechanosensing during cardiac regeneration
inferred← citeshttps://doi.org/10.70675/b409f12fz6cf5z41c1za540z203d9b096f89openalex-snapshot
Signalisation cellulaire et formation de complexes protéiques lors de l'étirement des cardiomyocytes de rats nouveaux-nés
inferred← citeshttps://doi.org/10.70675/c07bbc56zd023z4202z8e97z7449d29922c5openalex-snapshot
Physiopathologie de l'hypertension artérielle pulmonaire : rôles de la voie de signalisation TGF-β/ALK1/Endogline et de p53
inferred← citeshttps://doi.org/10.70675/d4895365zd459z4e19za2bcza381f1de771aopenalex-snapshot
Implication des facteurs locaux (CD9, HB-EGF, PDGF-BB) au sein des cellules épithéliales pariétales glomérulaires au cours de la glomérulonéphrite extracapillaire et de la hyalinose segmentaire et focale : Études in vitro et in vivo
inferred← citeshttps://doi.org/10.7717/peerj.17806openalex-snapshot
Production of recombinant human epidermal growth factor fused with HaloTag protein and characterisation of its biological functions
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