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Antioxidative and Hypolipidemic Effects of Diosgenin, a Steroidal Saponin of Yam (Dioscorea spp.), on High-Cholesterol Fed Rats
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/hep.20540openalex-snapshot
Diosgenin-induced biliary cholesterol secretion in mice requires Abcg8
inferredcites →https://doi.org/10.1002/hep.510280118openalex-snapshot
Effects of diosgenin, A plant-derived steroid, on bile secretion and hepatocellular cholestasis induced by estrogens in the rat
inferredcites →https://doi.org/10.1006/abio.1976.9999openalex-snapshot
A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding
inferredcites →https://doi.org/10.1006/meth.2001.1262openalex-snapshot
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
inferredcites →https://doi.org/10.1007/bf00916760openalex-snapshot
Erythrocyte-mediated scavenging of reactive oxygen metabolites generated by human polymorphonuclear leukocytes during phagocytosis: Comparison between normal and Down's syndrome blood cells
inferredcites →https://doi.org/10.1007/bf02876875openalex-snapshot
Steroidal sapogenin contents in some domestic plants
inferredcites →https://doi.org/10.1016/0009-8981(92)90109-4openalex-snapshot
Lipid peroxides in blood from patients with atherosclerosis of coronary and peripheral arteries
inferredcites →https://doi.org/10.1016/0009-8981(95)06192-4openalex-snapshot
Investigation of erythrocyte membrane lipid peroxidation and antioxidant defense systems of patients with coronary artery disease (CAD) documented by angiography
inferredcites →https://doi.org/10.1016/0014-4827(88)90265-0openalex-snapshot
A simple technique for quantitation of low levels of DNA damage in individual cells
inferredcites →https://doi.org/10.1016/0304-3835(95)03923-kopenalex-snapshot
Changes in lipoxygenase activities in human erythroleukemia (HEL) cells during diosgenin-induced differentiation
inferredcites →https://doi.org/10.1016/j.coph.2005.10.012openalex-snapshot
Raising high-density lipoprotein with cholesteryl ester transfer protein inhibitors
inferredcites →https://doi.org/10.1016/j.mrfmmm.2004.11.003openalex-snapshot
Relationship between DNA damage, total antioxidant capacity and coronary artery disease
inferredcites →https://doi.org/10.1016/s0014-5793(01)02924-6openalex-snapshot
A plant steroid, diosgenin, induces apoptosis, cell cycle arrest and COX activity in osteosarcoma cells
inferredcites →https://doi.org/10.1016/s0021-9258(18)54242-3openalex-snapshot
Differential regulation of antioxidant enzymes in response to oxidants.
inferredcites →https://doi.org/10.1016/s0022-2275(20)36843-7openalex-snapshot
Simplified spectrophotometric assay for microsomal 3-hydroxy-3-methylglutaryl CoA reductase by measurement of coenzyme A
inferredcites →https://doi.org/10.1016/s0022-2275(20)37819-6openalex-snapshot
Changes in biliary and fecal bile acids in mice after treatments with diosgenin and beta-sitosterol.
inferredcites →https://doi.org/10.1016/s0022-2275(20)40628-5openalex-snapshot
Effect of diosgenin on lipid metabolism in rats.
inferredcites →https://doi.org/10.1016/s0076-6879(84)05013-8openalex-snapshot
Superoxide dismutase assays.
inferredcites →https://doi.org/10.1016/s0076-6879(84)05042-4openalex-snapshot
[39] Assay for blood plasma or serum
inferredcites →https://doi.org/10.1016/s0168-8278(01)00125-8openalex-snapshot
Regulation of biliary cholesterol secretion is independent of hepatocyte canalicular membrane lipid composition: a study in the diosgenin-fed rat model
inferredcites →https://doi.org/10.1016/s1050-1738(03)00109-9openalex-snapshot
DNA Damage as a New Emerging Risk Factor in Atherosclerosis
inferredcites →https://doi.org/10.1016/s1359-6446(04)03211-8openalex-snapshot
Therapeutic control of free radicals
inferredcites →https://doi.org/10.1016/s1383-5718(01)00162-0openalex-snapshot
Evidence for DNA damage in patients with coronary artery disease
inferredcites →https://doi.org/10.1016/s1383-5718(01)00285-6openalex-snapshot
Determination of DNA damage induced by oxidative stress in hyperlipidemic patients
inferredcites →https://doi.org/10.1016/s1383-5742(02)00089-3openalex-snapshot
Coronary atherosclerosis and somatic mutations: an overview of the contributive factors for oxidative DNA damage
inferredcites →https://doi.org/10.1016/s1386-6346(03)00153-0openalex-snapshot
Regulation of biliary cholesterol secretion is associated with abcg5 and abcg8 expressions in the rats: effects of diosgenin and ethinyl estradiol
inferredcites →https://doi.org/10.1038/sj.onc.1209194openalex-snapshot
Diosgenin inhibits osteoclastogenesis, invasion, and proliferation through the downregulation of Akt, IκB kinase activation and NF-κB-regulated gene expression
inferredcites →https://doi.org/10.1042/bj2190001openalex-snapshot
Oxygen toxicity, oxygen radicals, transition metals and disease
inferredcites →https://doi.org/10.1042/bj2910793openalex-snapshot
Effect of diosgenin on biliary cholesterol transport in the rat
inferredcites →https://doi.org/10.1056/nejm199711063371906openalex-snapshot
Cardiovascular Medicine at the Turn of the Millennium: Triumphs, Concerns, and Opportunities
inferredcites →https://doi.org/10.1080/0963748021000044723openalex-snapshot
Effect of pure and oxidized cholesterol-rich diets on some biochemical parameters in rats
inferredcites →https://doi.org/10.1080/10715769800300661openalex-snapshot
Measuring oxidative damage to DNA; HPLC and the comet assay compared
inferredcites →https://doi.org/10.1093/clinchem/18.6.499openalex-snapshot
Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge
inferredcites →https://doi.org/10.1093/clinchem/37.11.1932openalex-snapshot
Biological variability of superoxide dismutase, glutathione peroxidase, and catalase in blood
inferredcites →https://doi.org/10.1097/00019501-200208000-00004openalex-snapshot
Elevated levels of oxidative DNA damage in patients with coronary artery disease
inferredcites →https://doi.org/10.1152/physrev.1994.74.1.139openalex-snapshot
Cellular defenses against damage from reactive oxygen species
inferredcites →https://doi.org/10.1161/01.atv.0000145574.90840.7dopenalex-snapshot
Reactive Oxygen Species
inferredcites →https://doi.org/10.1161/01.cir.0000026393.47805.21openalex-snapshot
Elevated Levels of Oxidative DNA Damage and DNA Repair Enzymes in Human Atherosclerotic Plaques
inferredcites →https://doi.org/10.1271/bbb.67.1451openalex-snapshot
Anti-obesity Effect ofDioscorea nipponicaMakino with Lipase-inhibitory Activity in Rodents
inferredcites →https://doi.org/10.1289/ehp.96104s3465openalex-snapshot
Oxidative damage to DNA: do we have a reliable biomarker?
inferredcites →https://doi.org/10.3892/ijmm.16.6.1095openalex-snapshot
Diosgenin, a plant steroid, induces apoptosis in COX-2 deficient K562 cells with activation of the p38 MAP kinase signalling and inhibition of NF-κB binding
inferredcites →https://doi.org/10.3892/ijo.28.1.201openalex-snapshot
Role of MAPKs and NF-κB in diosgenin-induced megakaryocytic differentiation and subsequent apoptosis in HEL cells
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4658480openalex-extracted
Oligopeptidase B of Dioscorea Opposita “Nagaimo”: Isolation, Biochemical Characterization, and Primary Structure
inferred← citeshttps://doi.org/10.2139/ssrn.4659223openalex-extracted
Purification of Phenolic Compounds from Camellia Polyodonta Flower: Composition Analysis, Antioxidant Property, and Hypolipidemic Activity in Vitro and in Vivo
inferred← citeshttps://doi.org/10.1002/ame2.70055openalex-snapshot
Diosgenin ameliorates silica‐induced tuberculosis in rats
inferred← citeshttps://doi.org/10.1002/bmc.5275openalex-snapshot
A novel UPLC–MS/MS method for simultaneous quantification of trigonelline, 4‐hydroxyisoleucine, and diosgenin from Trigonella foenum‐graecum extract: Application to pharmacokinetic study in healthy and type 2 diabetic rats
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Targeting transforming growth factor‐ß signalling for cancer prevention and intervention: Recent advances in developing small molecules of natural origin
inferred← citeshttps://doi.org/10.1002/ddr.21991openalex-snapshot
Therapeutic potential and research progress of diosgenin for lipid metabolism diseases
inferred← citeshttps://doi.org/10.1002/jsfa.5882openalex-snapshot
Influence of different particle processing on hypocholesterolemic and antiatherogenic activities of yam (Dioscorea pseudojaponica) in cholesterol‐fed rabbit model
inferred← citeshttps://doi.org/10.1002/jssc.200800295openalex-snapshot
Efficient protocol for purification of diosgenin and two fatty acids from Rhizoma dioscoreae by SFE coupled with high‐speed counter‐current chromatography and evaporative light scattering detection
inferred← citeshttps://doi.org/10.1002/mnfr.200900609openalex-snapshot
Diosgenin present in fenugreek improves glucose metabolism by promoting adipocyte differentiation and inhibiting inflammation in adipose tissues
inferred← citeshttps://doi.org/10.1002/pca.2887openalex-snapshot
New insights into diosgenin biosynthesis pathway and its regulation in Trigonella foenum‐graecum L.
inferred← citeshttps://doi.org/10.1002/pca.3165openalex-snapshot
Strategy of combining offline 2D LC‐MS with LC‐DIA‐MS/MS to accurately identify chemical compounds and for quality control of Dioscorea septemloba Thunb
inferred← citeshttps://doi.org/10.1007/978-3-030-04624-8_2openalex-snapshot
Fenugreek in Health and Disease
inferred← citeshttps://doi.org/10.1007/978-3-0348-0837-8_2openalex-snapshot
The Role of Inflammation in Colon Cancer
inferred← citeshttps://doi.org/10.1007/978-3-319-13401-7_10openalex-snapshot
Ecological Manipulations of Rhizobacteria for Curbing Medicinal Plant Diseases
inferred← citeshttps://doi.org/10.1007/978-3-319-54528-8_37-1openalex-snapshot
Roots and Tubers as Functional Foods
inferred← citeshttps://doi.org/10.1007/978-981-10-4017-7_21openalex-snapshot
Plant Products in the Management of Male Infertility
inferred← citeshttps://doi.org/10.1007/978-981-16-1197-1_19openalex-snapshot
Trigonella foenum-graecum and Its Bioactive Compounds Having Potential Antidiabetic Activity
inferred← citeshttps://doi.org/10.1007/s00253-012-4675-yopenalex-snapshot
Beneficial effects of phytoestrogens and their metabolites produced by intestinal microflora on bone health
inferred← citeshttps://doi.org/10.1007/s00425-020-03458-3openalex-snapshot
An underutilized orphan tuber crop—Chinese yam : a review
inferred← citeshttps://doi.org/10.1007/s10522-022-09955-0openalex-snapshot
Dietary intake of diosgenin delays aging of male fish Nothobranchius guentheri through modulation of multiple pathways that play prominent roles in ROS production
inferred← citeshttps://doi.org/10.1007/s11010-009-0058-9openalex-snapshot
Antilipoperoxidative and membrane stabilizing effect of diosgenin, in experimentally induced myocardial infarction
inferred← citeshttps://doi.org/10.1007/s11011-021-00880-8openalex-snapshot
Neuroprotective role of Diosgenin, a NGF stimulator, against Aβ (1–42) induced neurotoxicity in animal model of Alzheimer’s disease
inferred← citeshttps://doi.org/10.1007/s11064-020-03093-0openalex-snapshot
Diosgenin as a Novel Alternative Therapy for Inhibition of Growth, Invasion, and Angiogenesis Abilities of Different Glioblastoma Cell Lines
inferred← citeshttps://doi.org/10.1007/s11130-013-0345-1openalex-snapshot
Amelioration of Cholesterol Induced Atherosclerosis by Normalizing Gene Expression, Cholesterol Profile and Antioxidant Enzymes by Vigna unguiculata
inferred← citeshttps://doi.org/10.1007/s11240-018-1450-5openalex-snapshot
Application of the CRISPR/Cas9 system in Dioscorea zingiberensis
inferred← citeshttps://doi.org/10.1007/s11240-025-03022-5openalex-snapshot
Establishment of in vitro root cultures and hairy roots of Dioscorea composita for diosgenin production
inferred← citeshttps://doi.org/10.1007/s11483-020-09643-xopenalex-snapshot
Structure and Properties of Organogels Developed by Diosgenin in Canola Oil
inferred← citeshttps://doi.org/10.1007/s11694-021-00830-zopenalex-snapshot
Effects of yam (Dioscorea opposita Thunb.) juice on fermentation and textural attributes of set-style skimmed yoghurt
inferred← citeshttps://doi.org/10.1007/s11892-018-1042-0openalex-snapshot
Medicinal Plants with Multiple Effects on Diabetes Mellitus and Its Complications: a Systematic Review
inferred← citeshttps://doi.org/10.1007/s12010-016-2084-xopenalex-snapshot
Comparative Analysis of Proteins with Stimulating Activity on Ovarian Estradiol Biosynthesis from Four Different Dioscorea Species in vitro Using Both Phenotypic and Target-based Approaches: Implication for Treating Menopause
inferred← citeshttps://doi.org/10.1007/s12161-016-0685-1openalex-snapshot
Simultaneous Analysis of Free/Bound Phytosterols and Diosgenin in Taiwanese Yams
inferred← citeshttps://doi.org/10.1007/s12247-025-10339-3openalex-snapshot
Diosgenin-Loaded Silver Nanoparticles Mitigate Obesity-Related Metabolic Dysfunction: an Integrative Analysis of Biochemical, Transcriptional, and Molecular Docking Evidence
inferred← citeshttps://doi.org/10.1007/s12272-011-0617-yopenalex-snapshot
Effects of diosgenin on cell proliferation induced by IGF-1 in primary human thyrocytes
inferred← citeshttps://doi.org/10.1007/s12576-014-0333-8openalex-snapshot
Anti-arrhythmic effect of diosgenin in reperfusion-induced myocardial injury in a rat model: activation of nitric oxide system and mitochondrial KATP channel
inferred← citeshttps://doi.org/10.1007/s13105-012-0208-5openalex-snapshot
Preconditioning with diosgenin and treadmill exercise preserves the cardiac toxicity of isoproterenol in rats
inferred← citeshttps://doi.org/10.1007/s13105-014-0320-9openalex-snapshot
Diosgenin attenuates inflammatory response induced by myocardial reperfusion injury: role of mitochondrial ATP-sensitive potassium channels
inferred← citeshttps://doi.org/10.1007/s13596-024-00774-xopenalex-snapshot
Comparative efficacy of four potent bioactive molecules of fenugreek seed in holistic management of type 1 diabetes
inferred← citeshttps://doi.org/10.1007/s13659-012-0014-3openalex-snapshot
A review on pharmacological and analytical aspects of diosgenin: a concise report
inferred← citeshttps://doi.org/10.1007/s13659-014-0011-9openalex-snapshot
Hairy Root Induction in Helicteres isora L. and Production of Diosgenin in Hairy Roots
inferred← citeshttps://doi.org/10.1007/s42535-024-01148-zopenalex-snapshot
Ethnopharmacology, phytochemistry, pharmacological insights and toxicity assessment of Dioscorea bulbifera L.: a comprehensive review
inferred← citeshttps://doi.org/10.1007/s43555-024-00022-yopenalex-snapshot
Unveiling the Therapeutic Potential: Metabolomics Insights into Medicinal Plants and Their Antidiabetic Effects
inferred← citeshttps://doi.org/10.1016/b978-0-08-102922-0.00017-1openalex-snapshot
The chemical and pharmacological basis of fenugreek (Trigonella foenum-graecum L.) as potential therapy for type 2 diabetes and associated diseases
inferred← citeshttps://doi.org/10.1016/b978-0-12-405870-5.00023-2openalex-snapshot
Phytomedicines, Functional Foods, Nutraceuticals, and Their Regulation in Africa
inferred← citeshttps://doi.org/10.1016/b978-0-12-800874-4.00018-0openalex-snapshot
Botanicals as Medicinal Food and Their Effects against Obesity
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Phytomedicines, nutraceuticals, and functional foods regulatory framework
inferred← citeshttps://doi.org/10.1016/b978-0-443-06992-5.00009-8openalex-snapshot
Herbal approaches to system dysfunctions
inferred← citeshttps://doi.org/10.1016/b978-0-444-63294-4.00006-1openalex-snapshot
Antiobesity Effects of Natural Products from an Epigenetic Perspective
inferred← citeshttps://doi.org/10.1016/j.abb.2023.109759openalex-snapshot
Diosgenin prevents dexamethasone-induced myotube atrophy in C2C12 cells
inferred← citeshttps://doi.org/10.1016/j.ancard.2015.04.014openalex-snapshot
Relation entre structure et fonction de l’artère cérébrale « carotide » chez le rat Wistar soumis à un régime athérogène
inferred← citeshttps://doi.org/10.1016/j.arcmed.2018.01.004openalex-snapshot
Hypolipidemic Components from Medicine Food Homology Species Used in China: Pharmacological and Health Effects
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2012.06.012openalex-snapshot
Diosgenin ameliorates palmitate-induced endothelial dysfunction and insulin resistance via blocking IKKβ and IRS-1 pathways
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2015.02.044openalex-snapshot
Diosgenin inhibits atherosclerosis via suppressing the MiR-19b-induced downregulation of ATP-binding cassette transporter A1
inferred← citeshttps://doi.org/10.1016/j.bbrc.2019.01.010openalex-snapshot
Functional characterization of squalene epoxidase and NADPH-cytochrome P450 reductase in Dioscorea zingiberensis
inferred← citeshttps://doi.org/10.1016/j.bbrep.2025.102071openalex-snapshot
Isolation, biochemical characterization, and primary structure and active site determination of Dioscorea opposita (‘Nagaimo’) oligopeptidase B
inferred← citeshttps://doi.org/10.1016/j.biopha.2017.09.096openalex-snapshot
Diosgenin a phytosterol substitute for cholesterol, prolongs the lifespan and mitigates glucose toxicity via DAF-16/FOXO and GST-4 in Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1016/j.biopha.2018.03.167openalex-snapshot
Balanites aegyptiaca ameliorates insulin secretion and decreases pancreatic apoptosis in diabetic rats: Role of SAPK/JNK pathway
inferred← citeshttps://doi.org/10.1016/j.cbi.2009.02.013openalex-snapshot
Green tea catechins, alleviate hepatic lipidemic-oxidative injury in Wistar rats fed an atherogenic diet
inferred← citeshttps://doi.org/10.1016/j.cbi.2010.02.005openalex-snapshot
Protective effects of diosgenin in the hyperlipidemic rat model and in human vascular endothelial cells against hydrogen peroxide-induced apoptosis
inferred← citeshttps://doi.org/10.1016/j.cbi.2014.09.016openalex-snapshot
Isolation and prevention of calcium oxalate-induced apoptotic death and oxidative stress in MDCK cells by diosgenin
inferred← citeshttps://doi.org/10.1016/j.cclet.2009.11.018openalex-snapshot
New polyhydroxylated metabolite derived from biotransformation of diosgenin by the white-rot fungus Coriolus versicolor
inferred← citeshttps://doi.org/10.1016/j.ejmech.2015.05.018openalex-snapshot
Diosgenin-based thio(seleno)ureas and triazolyl glycoconjugates as hybrid drugs. Antioxidant and antiproliferative profile
inferred← citeshttps://doi.org/10.1016/j.ejphar.2011.03.016openalex-snapshot
Nitro-aspirin is a potential therapy for non alcoholic fatty liver disease
inferred← citeshttps://doi.org/10.1016/j.ejphar.2012.06.038openalex-snapshot
Beneficial role of diosgenin on oxidative stress in aorta of streptozotocin induced diabetic rats
inferred← citeshttps://doi.org/10.1016/j.ejphar.2014.07.026openalex-snapshot
Role of oxidative stress, inflammation, nitric oxide and transforming growth factor-beta in the protective effect of diosgenin in monocrotaline-induced pulmonary hypertension in rats
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Diosgenin attenuates nonalcoholic hepatic steatosis through the hepatic SIRT1/PGC-1α pathway
inferred← citeshttps://doi.org/10.1016/j.fct.2018.07.011openalex-snapshot
Diosgenin induces genotoxic and mutagenic effects on HepG2 cells
inferred← citeshttps://doi.org/10.1016/j.fitote.2023.105621openalex-snapshot
Synthesis, antioxidant, antiproliferative activity, molecular docking and DFT studies of novel isoxazole derivatives of diosgenin, a steroidal sapogenin from Dioscorea deltoidea
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Self-induced anaerobiosis coffee fermentation: Impact on microbial communities, chemical composition and sensory quality of coffee
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Diosgenin: Chemistry, extraction, quantification and health benefits
inferred← citeshttps://doi.org/10.1016/j.foodchem.2011.04.066openalex-snapshot
Beneficial effect of Ficus religiosa Linn. on high-fat-diet-induced hypercholesterolemia in rats
inferred← citeshttps://doi.org/10.1016/j.foodchem.2011.11.016openalex-snapshot
Prebiotic effect of diosgenin, an immunoactive steroidal sapogenin of the Chinese yam
inferred← citeshttps://doi.org/10.1016/j.foodchem.2020.126474openalex-snapshot
New insights into potential nutritional effects of dietary saponins in protecting against the development of obesity
inferred← citeshttps://doi.org/10.1016/j.fufo.2021.100068openalex-snapshot
Costus pictus–transition from a medicinal plant to functional food: A review
inferred← citeshttps://doi.org/10.1016/j.heliyon.2019.e01739openalex-snapshot
Antihyperlipidemic screening and plasma uric acid reducing potential of Momordica charantia seeds on Swiss albino mice model
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e31245openalex-snapshot
An overview on pharmacological significance, phytochemical potential, traditional importance and conservation strategies of Dioscorea deltoidea: A high valued endangered medicinal plant
inferred← citeshttps://doi.org/10.1016/j.hnm.2022.200147openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.136167openalex-snapshot
Extraction, separation and efficacy of yam polysaccharide
inferred← citeshttps://doi.org/10.1016/j.jchromb.2009.03.039openalex-snapshot
Development and validation of a sensitive and rapid non-aqueous LC–ESI-MS/MS method for measurement of diosgenin in the plasma of normal and hyperlipidemic rats: A comparative study
inferred← citeshttps://doi.org/10.1016/j.jddst.2021.102766openalex-snapshot
Assessment of behavioral changes and antitumor effects of silver nanoparticles synthesized using diosgenin in mice model
inferred← citeshttps://doi.org/10.1016/j.jddst.2025.107468openalex-snapshot
Formulation of a novel diosgenin-loaded nanoemulsion and its evaluation for improved brain bioavailability in the management of cerebral ischemia
inferred← citeshttps://doi.org/10.1016/j.jep.2023.117478openalex-snapshot
GC-MS analysis and potential therapeutic efficacy of extracts from Allium humile Kunth in lowering dyslipidemia in wistar rat models
inferred← citeshttps://doi.org/10.1016/j.jfca.2021.104010openalex-snapshot
Caryatin and 3’-O-methylcaryatin contents in edible yams (Dioscorea spp.)
inferred← citeshttps://doi.org/10.1016/j.jfca.2025.108085openalex-snapshot
Investigating the dynamic changes in chemical profiles and antidiabetic potential of fenugreek sprouts across germination stages using UHPLC-QqQ-MS combined with chemometrics
inferred← citeshttps://doi.org/10.1016/j.jff.2017.11.002openalex-snapshot
Estrogenic activity of yam via a yeast model and its effects on two cancer cell lines
inferred← citeshttps://doi.org/10.1016/j.jpba.2015.08.038openalex-snapshot
Comparative analysis of steroidal saponins in four Dioscoreae herbs by high performance liquid chromatography coupled with mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.lfs.2020.118182openalex-snapshot
Diosgenin, a steroidal saponin, and its analogs: Effective therapies against different chronic diseases
inferred← citeshttps://doi.org/10.1016/j.molcatb.2010.09.001openalex-snapshot
Microbiological transformation of diosgenin by resting cells of filamentous fungus, Cunninghamella echinulata CGMCC 3.2716
inferred← citeshttps://doi.org/10.1016/j.nutres.2009.05.008openalex-snapshot
Karaya root saponin exerts a hypocholesterolemic response in rats fed a high-cholesterol diet
inferred← citeshttps://doi.org/10.1016/j.pbb.2014.01.012openalex-snapshot
Comparison of behavioral and biochemical deficits in rats with hereditary defined or d-galactose-induced accelerated senescence: Evaluating the protective effects of diosgenin
inferred← citeshttps://doi.org/10.1016/j.phymed.2010.09.007openalex-snapshot
Hypolipidemic and antioxidant activities of Sanchi (Radix Notoginseng) in rats fed with a high fat diet
inferred← citeshttps://doi.org/10.1016/j.phymed.2014.04.005openalex-snapshot
Efficacy of natural diosgenin on cardiovascular risk, insulin secretion, and beta cells in streptozotocin (STZ)-induced diabetic rats
inferred← citeshttps://doi.org/10.1016/j.phymed.2024.155684openalex-snapshot
Immune-inflammatory modulation by natural products derived from edible and medicinal herbs used in Chinese classical prescriptions
inferred← citeshttps://doi.org/10.1016/j.phyplu.2023.100497openalex-snapshot
Paris polyphylla Sm. extract enriched with diosgenin as an antidiabetic agent: In vitro and in vivo study
inferred← citeshttps://doi.org/10.1016/j.phytol.2014.07.006openalex-snapshot
Two novel saponins from Cephalaria davisiana (Dipsacaceae)
inferred← citeshttps://doi.org/10.1016/j.phytol.2019.01.012openalex-snapshot
GC-MS analysis of steroids and triterpenoids occurring in leaves and tubers of Tamus edulis Lowe
inferred← citeshttps://doi.org/10.1016/j.prmcm.2023.100226openalex-snapshot
Exploring the phytochemistry, pharmacognostic properties, and pharmacological activities of medically important plant Momordica Charantia
inferred← citeshttps://doi.org/10.1016/j.psj.2025.104958openalex-snapshot
The integrated analysis of transcriptomics and metabolomics reveals the effects of tea polyphenols on lipid metabolism in lion-head geese
inferred← citeshttps://doi.org/10.1016/j.sajb.2020.07.028openalex-snapshot
Dioscorea bulbifera L. (Dioscoreaceae): A review of its ethnobotany, pharmacology and conservation needs
inferred← citeshttps://doi.org/10.1016/j.steroids.2009.01.006openalex-snapshot
Novel effects of diosgenin on skin aging
inferred← citeshttps://doi.org/10.1016/j.steroids.2014.08.019openalex-snapshot
Development of a new certified reference material of diosgenin using mass balance approach and Coulometric titration method
inferred← citeshttps://doi.org/10.1016/j.steroids.2016.07.002openalex-snapshot
Quantitative determination of gracillin by HPLC–MS/MS after oral administration and its application to a pharmacokinetic study
inferred← citeshttps://doi.org/10.1016/j.steroids.2016.11.003openalex-snapshot
Synthesis and biological evaluation of novel 3- O -tethered triazoles of diosgenin as potent antiproliferative agents
inferred← citeshttps://doi.org/10.1016/j.steroids.2022.108980openalex-snapshot
Anti-apoptotic effects of diosgenin on ovariectomized hearts
inferred← citeshttps://doi.org/10.1016/j.steroids.2022.109115openalex-snapshot
Antioxidant activity of novel diosgenin derivatives: Synthesis, biological evaluation, and in silico ADME prediction
inferred← citeshttps://doi.org/10.1016/j.tifs.2020.07.026openalex-snapshot
Effects of phytochemicals from plant-based functional foods on hyperlipidemia and their underpinning mechanisms
inferred← citeshttps://doi.org/10.1016/j.ymben.2022.01.013openalex-snapshot
Metabolic engineering of Saccharomyces cerevisiae for gram-scale diosgenin production
inferred← citeshttps://doi.org/10.1016/s1875-5364(15)30053-4openalex-snapshot
Advances in the pharmacological activities and mechanisms of diosgenin
inferred← citeshttps://doi.org/10.1016/s2221-6189(14)60029-9openalex-snapshot
Hypolipidemic activity of Piper betel in high fat diet induced hyperlipidemic rat
inferred← citeshttps://doi.org/10.1021/acs.jafc.2c08478openalex-snapshot
Biosynthetic Gene Expression and Tissue Distribution of Diosgenin in Dioscorea japonica
inferred← citeshttps://doi.org/10.1021/acs.jafc.8b03040openalex-snapshot
Effects of Sanyaku and Its Constituent Diosgenin on the Fasted and Postprandial Hypertriacylglycerolemia in High-Fat-Diet-Fed KK-Ay Mice
inferred← citeshttps://doi.org/10.1021/jf103965bopenalex-snapshot
Food Grade Lingonberry Extract: Polyphenolic Composition and In Vivo Protective Effect against Oxidative Stress
inferred← citeshttps://doi.org/10.1021/jf201640jopenalex-snapshot
Osteoprotective Effect of Monascus-fermented Dioscorea in Ovariectomized Rat Model of Postmenopausal Osteoporosis
inferred← citeshttps://doi.org/10.1021/jf304036copenalex-snapshot
Preparation of Nano/Submicrometer Yam and Its Benefits on Collagen Secretion from Skin Fibroblast Cells
inferred← citeshttps://doi.org/10.1039/c1np00035gopenalex-snapshot
Natural products in anti-obesity therapy
inferred← citeshttps://doi.org/10.1039/c3fo30194jopenalex-snapshot
Vigna unguiculata modulates cholesterol induced cardiac markers, genotoxicity and gene expressions profile in an experimental rabbit model
inferred← citeshttps://doi.org/10.1039/c5ra10761jopenalex-snapshot
Systems pharmacology and molecular docking strategies prioritize natural molecules as cardioprotective agents
inferred← citeshttps://doi.org/10.1039/c9fo00749kopenalex-snapshot
Effects of diosgenin and its derivatives on atherosclerosis
inferred← citeshttps://doi.org/10.1055/a-2779-6570openalex-snapshot
Dioscorea bulbifera: Phytotherapeutic Potential and Toxicological Risks, A Critical Review
inferred← citeshttps://doi.org/10.1063/5.0232926openalex-snapshot
Studying the effect of diosgenin and doxorubicin on SOD and CAT enzymes using zebrafish larvae models under stress condition
inferred← citeshttps://doi.org/10.1080/01635580802357352openalex-snapshot
Cancer Chemopreventive and Therapeutic Effects of Diosgenin, a Food Saponin
inferred← citeshttps://doi.org/10.1080/10408398.2022.2101425openalex-snapshot
New insights into anti-diabetes effects and molecular mechanisms of dietary saponins
inferred← citeshttps://doi.org/10.1080/14786419.2011.570760openalex-snapshot
Efficacy ofFicusspp. on renal injury induced by hypercholesterolaemia
inferred← citeshttps://doi.org/10.1088/1755-1315/515/1/012055openalex-snapshot
Increasing Health Benefit of Wild Yam (Dioscorea hispida) Tuber by Red Mold (Angkak) Fermentation
inferred← citeshttps://doi.org/10.1088/1755-1315/559/1/012004openalex-snapshot
Subcritical water extraction of Diosgenin from Dioscorea nipponica Makino and its antioxidant activity
inferred← citeshttps://doi.org/10.1089/jmf.2009.0034openalex-snapshot
Active Principle of Kimchi, 3-(4′-Hydroxyl-3′,5′-Dimethoxyphenyl)propionic Acid, Retards Fatty Streak Formation at Aortic Sinus of Apolipoprotein E Knockout Mice
inferred← citeshttps://doi.org/10.1089/jmf.2013.0140openalex-snapshot
Effects of Jamaican Bitter Yam ( Dioscorea polygonoides ) and Diosgenin on Blood and Fecal Cholesterol in Rats
inferred← citeshttps://doi.org/10.1089/jmf.2021.k.0086openalex-snapshot
Orally Administered Diosgenin Alleviates Colitis in Mice Induced by Dextran Sulfate Sodium through Gut Microbiota Modulation and Short-Chain Fatty Acid Generation
inferred← citeshttps://doi.org/10.1093/ecam/neq032openalex-snapshot
Dioscorea Phytocompounds Enhance Murine Splenocyte Proliferation Ex Vivo and Improve Regeneration of Bone Marrow Cells In Vivo
inferred← citeshttps://doi.org/10.1109/hhbe.2011.6028965openalex-snapshot
Progress in the studies on effective components of Chinese medicine in the treatment of hyperlipidemia
inferred← citeshttps://doi.org/10.1111/1750-3841.12787openalex-snapshot
Role of Effective Composition on Antioxidant, Anti‐inflammatory, Sedative‐Hypnotic Capacities of 6 Common Edible Lilium Varieties
inferred← citeshttps://doi.org/10.1111/jfbc.12022openalex-snapshot
Effects ofDioscorea Polygonoides(Jamaican Bitter Yam) Supplementation in Normocholesterolemic and Genetically Modified Hypercholesterolemic Mice Species
inferred← citeshttps://doi.org/10.1124/pr.118.017178openalex-snapshot
Targeting Foam Cell Formation in Atherosclerosis: Therapeutic Potential of Natural Products
inferred← citeshttps://doi.org/10.1142/s0192415x11009020openalex-snapshot
Diosgenin Ameliorates Cognition Deficit and Attenuates Oxidative Damage in Senescent Mice Induced by D-Galactose
inferred← citeshttps://doi.org/10.1142/s0192415x20500202openalex-snapshot
Anti-Apoptotic Effects of Diosgenin in D-Galactose-Induced Aging Brain
inferred← citeshttps://doi.org/10.1145/3340037.3340053openalex-snapshot
Meta-analysis of Yam's Effects on Liver Injury Protection and Blood Lipid-lowering
inferred← citeshttps://doi.org/10.1155/2016/3631647openalex-snapshot
Roots and Tuber Crops as Functional Foods: A Review on Phytochemical Constituents and Their Potential Health Benefits
inferred← citeshttps://doi.org/10.1155/2016/4156293openalex-snapshot
Diosgenin: Recent Highlights on Pharmacology and Analytical Methodology
inferred← citeshttps://doi.org/10.1155/2019/3231424openalex-snapshot
The Role of Traditional Chinese Medicine in the Regulation of Oxidative Stress in Treating Coronary Heart Disease
inferred← citeshttps://doi.org/10.1155/2023/3269293openalex-snapshot
Effect of Saengmaeksan on Fatigue, Liver Function, and Immunity Combined with High-Intensity Training
inferred← citeshttps://doi.org/10.1158/1940-6207.capr-10-0279openalex-snapshot
Chemoprevention of Azoxymethane/Dextran Sodium Sulfate–Induced Mouse Colon Carcinogenesis by Freeze-Dried Yam Sanyaku and Its Constituent Diosgenin
inferred← citeshttps://doi.org/10.1177/0267659114566064openalex-snapshot
Diosgenin-induced protection against myocardial ischaemia-reperfusion injury is mediated by mitochondrial K ATP channels in a rat model
inferred← citeshttps://doi.org/10.1186/s12903-024-04646-3openalex-snapshot
Assessment and comparative study of diosgenin doses in alleviating experimental periodontitis
inferred← citeshttps://doi.org/10.1186/s13765-025-00996-wopenalex-snapshot
The antioxidant activity of diosgenin, a plant steroid sapogenin, in C2C12 myoblasts is achieved by blocking mitochondrial ROS production
inferred← citeshttps://doi.org/10.1186/s43094-020-00106-1openalex-snapshot
Botanical description, phytochemistry, traditional uses, and pharmacology of Crataeva nurvala Buch. Ham.: an updated review
inferred← citeshttps://doi.org/10.1194/jlr.m800631-jlr200openalex-snapshot
Diosgenin stimulation of fecal cholesterol excretion in mice is not NPC1L1 dependent
inferred← citeshttps://doi.org/10.1201/9781315370859-15openalex-snapshot
Industrial Production of Nanonutraceuticals
inferred← citeshttps://doi.org/10.1201/9781315370859-6openalex-snapshot
Targeted Delivery of Nutraceuticals Using Nanoparticles
inferred← citeshttps://doi.org/10.1248/bpb.34.1021openalex-snapshot
Batatasin I, a Naturally Occurring Phenanthrene Derivative, Isolated from Tuberous Roots of Dioscorea batatas Suppresses Eicosanoids Generation and Degranulation in Bone Marrow Derived-Mast Cells
inferred← citeshttps://doi.org/10.1248/bpb.b15-00849openalex-snapshot
Anti-obesity Effect of Dioscorea oppositifolia Extract in High-Fat Diet-Induced Obese Mice and Its Chemical Characterization
inferred← citeshttps://doi.org/10.12677/hjmce.2014.24007openalex-snapshot
The New Idea in the Synthesis of Lipid-Regulator Fibrates
inferred← citeshttps://doi.org/10.12944/crnfsj.6.2.11openalex-snapshot
Bitter Melon (Momordica charantia L) Fruit Decreased Blood Glucose Level and Improved Lipid Profile of Streptozotocin Induced Hyperglycemia Rats
inferred← citeshttps://doi.org/10.1371/journal.pone.0020164openalex-snapshot
Diosgenin, a Steroidal Saponin, Inhibits Migration and Invasion of Human Prostate Cancer PC-3 Cells by Reducing Matrix Metalloproteinases Expression
inferred← citeshttps://doi.org/10.1371/journal.pone.0106039openalex-snapshot
Diosgenin from Dioscorea bulbifera: Novel Hit for Treatment of Type II Diabetes Mellitus with Inhibitory Activity against α-Amylase and α-Glucosidase
inferred← citeshttps://doi.org/10.14710/jitaa.38.3.176-184openalex-snapshot
EFFECT OF SAUROPUS ANDROGYNUS LEAVES EXTRACT (SALE) ON FAT DEPOSITION IN BROILER FED LOW PROTEIN DIETS
inferred← citeshttps://doi.org/10.14748/vmf.v10i2.7936openalex-snapshot
Use Of Cinnamomum Spp., Cichorium Intybus, Trigonella Foenum-Graecum In Type Ii Diabetes Mellitus
inferred← citeshttps://doi.org/10.1590/fst.119121openalex-snapshot
Cyanogenic compounds removal and characteristics of non- and pregelatinized traditional detoxified wild yam (Dioscorea hispida) tuber flour
inferred← citeshttps://doi.org/10.1590/s0036-46652011000300007openalex-snapshot
Therapeutic Effects of Allium sativum and Allium cepa in Schistosoma mansoni experimental infection
inferred← citeshttps://doi.org/10.17495/easdl.2015.10.25.5.880openalex-snapshot
Physicochemical Composition and Antioxidant Activities of Korean Dioscorea Species
inferred← citeshttps://doi.org/10.17795/jjnpp-17187openalex-snapshot
Protective Effects of Crocin on Ischemia-reperfusion Induced Oxidative Stress in Comparison With Vitamin E in Isolated Rat Hearts
inferred← citeshttps://doi.org/10.18551/rjoas.2018-07.34openalex-snapshot
BIOACTIVE COMPOUND AND NUTRITIOUS CHARACTERISTIC OF BITTER MELON FRUIT (MOMORDICA CHARANTIA L.)
inferred← citeshttps://doi.org/10.20546/ijcmas.2018.707.375openalex-snapshot
Saponin in Poultry and Monogastric Animals: A Review
inferred← citeshttps://doi.org/10.2147/dddt.s368836openalex-snapshot
Diosgenin and Its Analogs: Potential Protective Agents Against Atherosclerosis
inferred← citeshttps://doi.org/10.2147/dddt.s370506openalex-snapshot
Dioscin Regulating Bone Marrow Apoptosis in Aplastic Anemia
inferred← citeshttps://doi.org/10.2147/dmso.s326054openalex-snapshot
The Effects of Diosgenin on Hypolipidemia and Its Underlying Mechanism: A Review
inferred← citeshttps://doi.org/10.2147/ott.s237474openalex-snapshot
Diosgenin and GSK126 Produce Synergistic Effects on Epithelial–Mesenchymal Transition in Gastric Cancer Cells by Mediating EZH2 via the Rho/ROCK Signaling Pathway
inferred← citeshttps://doi.org/10.21577/1984-6835.20190090openalex-snapshot
Development and Validation of Sensitive HPLC-UV-DAD Method for Determination of Diosgenin in Plants of Species of Dioscorea Genus
inferred← citeshttps://doi.org/10.21608/ajs.2022.131489.1475openalex-snapshot
Steroidal Saponin as Antioxidant and Alleviator of CCl4-Induced Oxidative Damage in Albino Rats.
inferred← citeshttps://doi.org/10.2174/2215083809666230202143136openalex-snapshot
Anticancer Potential of Biologically Active Diosgenin and its Derivatives: An Update
inferred← citeshttps://doi.org/10.2174/9781608059140114020005openalex-snapshot
Herbal and Microbial Products for the Management of Obesity
inferred← citeshttps://doi.org/10.2174/9781681089492122020009openalex-snapshot
Fenugreek (Trigonella foenum-graecum L.): A Palatable Spice, An Active Herb, A Promising Functional Food, and Even More
inferred← citeshttps://doi.org/10.22038/ijbms.2011.5004openalex-snapshot
Protective Effect of Diosgenin and Exercise Training on Biochemical and ECG Alteration in Isoproterenol- Induced Myocardial Infarction in Rats
inferred← citeshttps://doi.org/10.22038/ijbms.2023.68801.14995openalex-snapshot
Therapeutic effects of diosgenin on alveolar bone loss and apoptosis in diabetic rats with experimental periodontitis.
inferred← citeshttps://doi.org/10.22270/jddt.v14i11.6878openalex-snapshot
EXTRACTION, Extraction, Isolation, Identification and Estimation of Diosgenin by TLC Profiling and UHPLC-LC-SRM Analysis in Three Costus Species
inferred← citeshttps://doi.org/10.22271/phyto.2021.v10.i5c.14194openalex-snapshot
Natural remedies for hyperlipidemia: A review
inferred← citeshttps://doi.org/10.2306/scienceasia1513-1874.2022.123openalex-snapshot
Effect of diosgenin in the inhibition of gastric cancer cell proliferation and its mechanism in combination with TRAIL to induce apoptosis
inferred← citeshttps://doi.org/10.25081/jp.2022.v14.7769openalex-snapshot
Expression analysis of diosgenin pathway genes and diosgenin accumulation in fenugreek sprouts after exposure to copper sulfate
inferred← citeshttps://doi.org/10.2741/e159openalex-snapshot
Nature versus nurture - plant resources in management of male infertility
inferred← citeshttps://doi.org/10.31015/jaefs.2021.2.7openalex-snapshot
Current perspectives on the Nutrient composition and health benefits of yams (Discorea species)
inferred← citeshttps://doi.org/10.3109/19390211.2014.952860openalex-snapshot
Renal and Hepatic Function in Hypercholesterolemic Rats Fed Jamaican Bitter Yam(Dioscorea polygonoides)
inferred← citeshttps://doi.org/10.3136/fstr.fstr-d-25-00072openalex-snapshot
Physical properties and palatability of vacuum-fried snacks from underutilized bulbils of Dioscorea japonica Thunb.
inferred← citeshttps://doi.org/10.3136/nskkk.58.567openalex-snapshot
Chemical Composition of Lipids in Freeze-Dried Tubers of Chinese Yam Harvested in Hokkaido and Their Growth Inhibition of Human Colon Cancer Cells
inferred← citeshttps://doi.org/10.3136/nskkk.59.538openalex-snapshot
Nutrient Composition, Amylase Titer, and Superoxide Anion-Scavenging Activity of Chinese Yam Tubers Harvested in Hokkaido
inferred← citeshttps://doi.org/10.3164/jcbn.17-54openalex-snapshot
Preventive effect of Dioscorea japonica on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E2 synthetic pathway
inferred← citeshttps://doi.org/10.3168/jds.2020-18980openalex-snapshot
Supplementation with Yucca schidigera improves antioxidant capability and immune function and decreases fecal score of dairy calves before weaning
inferred← citeshttps://doi.org/10.3389/fendo.2022.901545openalex-snapshot
Evolving Roles of Natural Terpenoids From Traditional Chinese Medicine in the Treatment of Osteoporosis
inferred← citeshttps://doi.org/10.3389/fmolb.2024.1303379openalex-snapshot
Diosgenin alleviates D-galactose-induced oxidative stress in rats’ brain and liver targeting aging and apoptotic marker genes
inferred← citeshttps://doi.org/10.3389/fnins.2021.806713openalex-snapshot
Fabrication and Assessment of Diosgenin Encapsulated Stearic Acid Solid Lipid Nanoparticles for Its Anticancer and Antidepressant Effects Using in vitro and in vivo Models
inferred← citeshttps://doi.org/10.3389/fphar.2017.00052openalex-snapshot
Dioscorea spp. (A Wild Edible Tuber): A Study on Its Ethnopharmacological Potential and Traditional Use by the Local People of Similipal Biosphere Reserve, India
inferred← citeshttps://doi.org/10.3389/fphar.2017.00436openalex-snapshot
An Overview of Herbal Products and Secondary Metabolites Used for Management of Type Two Diabetes
inferred← citeshttps://doi.org/10.3390/agronomy11020394openalex-snapshot
Suspension Cell Culture of Dioscorea deltoidea—A Renewable Source of Biomass and Furostanol Glycosides for Food and Pharmaceutical Industry
inferred← citeshttps://doi.org/10.3390/antiox13060662openalex-snapshot
Purification of Phenolic Compounds from Camellia polyodonta Flower: Composition Analysis, Antioxidant Property, and Hypolipidemic Activity In Vitro and In Vivo
inferred← citeshttps://doi.org/10.3390/bioengineering11111098openalex-snapshot
Screening and Selection of a New Medium and Culture Conditions for Diosgenin Production via Microbial Biocatalysis of SYt1
inferred← citeshttps://doi.org/10.3390/foods11152263openalex-snapshot
Suitability of Banana and Plantain Fruits in Modulating Neurodegenerative Diseases: Implicating the In Vitro and In Vivo Evidence from Neuroactive Narratives of Constituent Biomolecules
inferred← citeshttps://doi.org/10.3390/ijms13056521openalex-snapshot
Anti-Proliferation and Anti-Invasion Effects of Diosgenin on Gastric Cancer BGC-823 Cells with HIF-1α shRNAs
inferred← citeshttps://doi.org/10.3390/ijms150917130openalex-snapshot
High-Dose Diosgenin Reduces Bone Loss in Ovariectomized Rats via Attenuation of the RANKL/OPG Ratio
inferred← citeshttps://doi.org/10.3390/ijms26031088openalex-snapshot
Preparation of Diosgenin-Functionalized Gold Nanoparticles: From Synthesis to Antitumor Activities
inferred← citeshttps://doi.org/10.3390/molecules23010105openalex-snapshot
Phytotherapy in the Management of Diabetes: A Review
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