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Multistable Decision Switches for Flexible Control of Epigenetic Differentiation
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Outgoing claims: the papers this work cites, builds on, or argues with.
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How to make a Biological Switch
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The Growth Regulators warts/lats and melted Interact in a Bistable Loop to Specify Opposite Fates in Drosophila R8 Photoreceptors
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CD4/CD8 lineage commitment: light at the end of the tunnel?
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T helper cell effector fates — who, how and where?
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Molecular control of pluripotency
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Negotiation of the T Lineage Fate Decision by Transcription-Factor Interplay and Microenvironmental Signals
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High-dimensional switches and the modelling of cellular differentiation
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Towards an understanding of lineage specification in hematopoietic stem cells: A mathematical model for the interaction of transcription factors GATA-1 and PU.1
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Monte Carlo simulation of a simple gene network yields new evolutionary insights
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Sox9 is required for notochord maintenance in mice
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Bifurcation dynamics in lineage-commitment in bipotent progenitor cells
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A Homeodomain Protein Code Specifies Progenitor Cell Identity and Neuronal Fate in the Ventral Neural Tube
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Development of Genetic Circuitry Exhibiting Toggle Switch or Oscillatory Behavior in Escherichia coli
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New perspectives on a developmental dilemma: the kinetic signaling model and the importance of signal duration for the CD4/CD8 lineage decision
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Notch signalling in development: on equivalence groups and asymmetric developmental potential
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Robustness, Flexibility, and the Role of Lateral Inhibition in the Neurogenic Network
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Myeloid or Lymphoid Promiscuity as a Critical Step in Hematopoietic Lineage Commitment
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Neuronal specification in the spinal cord: inductive signals and transcriptional codes
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Diversification of haematopoietic stem cells to specific lineages
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Multistability in the lactose utilization network of Escherichia coli
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Cross-talk and decision making in MAP kinase pathways
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Cell lineage regulators in B and T cell development
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Stochasticity in gene expression: from theories to phenotypes
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Chromatin modification and epigenetic reprogramming in mammalian development
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Regulation of hematopoietic stem cell fate
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Nonlinear Dynamics and Chaos: With Applications to Physics, Biology, Chemistry, and Engineering
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Contingent gene regulatory networks and B cell fate specification
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MicroRNAs acting in a double-negative feedback loop to control a neuronal cell fate decision
inferredcites →https://doi.org/10.1073/pnas.0701014104openalex-snapshot
A gene regulatory network in mouse embryonic stem cells
inferredcites →https://doi.org/10.1073/pnas.0704054104openalex-snapshot
Sox9 coordinates a transcriptional network in pancreatic progenitor cells
inferredcites →https://doi.org/10.1073/pnas.1332628100openalex-snapshot
Prediction and measurement of an autoregulatory genetic module
inferredcites →https://doi.org/10.1074/jbc.m502573200openalex-snapshot
Transcriptional Regulation of Nanog by OCT4 and SOX2
inferredcites →https://doi.org/10.1101/gad.1281105openalex-snapshot
An initial blueprint for myogenic differentiation
inferredcites →https://doi.org/10.1101/sqb.1961.026.01.048openalex-snapshot
General Conclusions: Teleonomic Mechanisms in Cellular Metabolism, Growth, and Differentiation
inferredcites →https://doi.org/10.1126/science.1068873openalex-snapshot
MAP Kinase Phosphatase As a Locus of Flexibility in a Mitogen-Activated Protein Kinase Signaling Network
inferredcites →https://doi.org/10.1126/science.1103336openalex-snapshot
T Helper Cell Fate Specified by Kinase-Mediated Interaction of T-bet with GATA-3
inferredcites →https://doi.org/10.1126/science.1104171openalex-snapshot
Flexible Control of Mutual Inhibition: A Neural Model of Two-Interval Discrimination
inferredcites →https://doi.org/10.1126/science.1113319openalex-snapshot
Stimulus Specificity of Gene Expression Programs Determined by Temporal Control of IKK Activity
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A mechanism for the sharp transition of morphogen gradient interpretation in Xenopus
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An Introduction to Systems Biology
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An Introduction to Systems Biology
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How is pluripotency determined and maintained?
inferredcites →https://doi.org/10.1242/dev.127.20.4325openalex-snapshot
Spatial specification of mammalian eye territories by reciprocal transcriptional repression of Pax2 and Pax6
inferredcites →https://doi.org/10.1371/journal.pcbi.0020030openalex-snapshot
Dynamical Principles of Two-Component Genetic Oscillators
inferredcites →https://doi.org/10.1371/journal.pcbi.0020120openalex-snapshot
Mathematical Modeling Identifies Inhibitors of Apoptosis as Mediators of Positive Feedback and Bistability
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Transcriptional Dynamics of the Embryonic Stem Cell Switch
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A Recurrent Network Mechanism of Time Integration in Perceptual Decisions
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Incoming claims: where this work appears in other papers’ reference lists and arguments.
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A multiscale model of complex endothelial cell dynamics in early angiogenesis
inferred← citeshttps://doi.org/10.1371/journal.pgen.1006353openalex-snapshot
A Multistate Toggle Switch Defines Fungal Cell Fates and Is Regulated by Synergistic Genetic Cues
inferred← citeshttps://doi.org/10.1371/journal.pone.0032779openalex-snapshot
Speed-Dependent Cellular Decision Making in Nonequilibrium Genetic Circuits
inferred← citeshttps://doi.org/10.1371/journal.pone.0035291openalex-snapshot
Strategic Cell-Cycle Regulatory Features That Provide Mammalian Cells with Tunable G1 Length and Reversible G1 Arrest
inferred← citeshttps://doi.org/10.1371/journal.pone.0040085openalex-snapshot
Interplay between Path and Speed in Decision Making by High-Dimensional Stochastic Gene Regulatory Networks
inferred← citeshttps://doi.org/10.1371/journal.pone.0095744openalex-snapshot
Competition in Notch Signaling with Cis Enriches Cell Fate Decisions
inferred← citeshttps://doi.org/10.15252/msb.20199361openalex-snapshot
Controlling spatiotemporal pattern formation in a concentration gradient with a synthetic toggle switch
inferred← citeshttps://doi.org/10.18632/oncotarget.4629openalex-snapshot
Coupling the modules of EMT and stemness: A tunable ‘stemness window’ model
inferred← citeshttps://doi.org/10.2139/ssrn.7235438openalex-snapshot
Nucleosome Deformation Dynamics Determine a Quantitative Stability Threshold for Epigenetic Memory
inferred← citeshttps://doi.org/10.2139/ssrn.7471128openalex-snapshot
Nucleosome Deformation Dynamics Determine a Quantitative Stability Threshold for Epigenetic Memory
inferred← citeshttps://doi.org/10.2478/s11534-013-0190-8openalex-snapshot
Two novel aspects of the kinetics of gene expression including miRNAs
inferred← citeshttps://doi.org/10.3389/fonc.2015.00155openalex-snapshot
Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis
inferred← citeshttps://doi.org/10.3390/biom12121842openalex-snapshot
Functional Resilience of Mutually Repressing Motifs Embedded in Larger Networks
inferred← citeshttps://doi.org/10.3390/cells10112863openalex-snapshot
An Integrated View of Virus-Triggered Cellular Plasticity Using Boolean Networks
inferred← citeshttps://doi.org/10.3390/ijms22136944openalex-snapshot
Feedback, Crosstalk and Competition: Ingredients for Emergent Non-Linear Behaviour in the PI3K/mTOR Signalling Network
inferred← citeshttps://doi.org/10.3390/jcm10030472openalex-snapshot
Multi-Stability and Consequent Phenotypic Plasticity in AMPK-Akt Double Negative Feedback Loop in Cancer Cells
inferred← citeshttps://doi.org/10.3390/jcm9030870openalex-snapshot
Emergent Properties of the HNF4α-PPARγ Network May Drive Consequent Phenotypic Plasticity in NAFLD
inferred← citeshttps://doi.org/10.3934/dcdsb.2023214openalex-snapshot
Long-time behaviour of an advection-selection equation
inferred← citeshttps://doi.org/10.4995/thesis/10251/14179openalex-snapshot
Computational design and designability of gene regulatory networks
inferred← citeshttps://doi.org/10.64898/2026.02.04.703680openalex-snapshot
Hierarchical organization in sparse gene regulatory networks shapes structural coherence and emergent regulatory coordination
inferred← citeshttps://doi.org/10.64898/2026.03.04.709512openalex-snapshot
A Latent Space Thermodynamic Model of Cell Differentiation
inferred← citeshttps://doi.org/10.7554/elife.23702openalex-snapshot
Engineering of a synthetic quadrastable gene network to approach Waddington landscape and cell fate determination
inferred← citeshttps://doi.org/10.7554/elife.64522openalex-snapshot
Topological signatures in regulatory network enable phenotypic heterogeneity in small cell lung cancer
inferred← citeshttps://doi.org/10.7554/elife.76535openalex-snapshot
Landscape of epithelial–mesenchymal plasticity as an emergent property of coordinated teams in regulatory networks
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