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Time-resolved proteomic profile of Amblyomma americanum tick saliva during feeding

https://doi.org/10.1371/journal.pntd.0007758

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Outgoing claims: the papers this work cites, builds on, or argues with.

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SMART: a web-based tool for the study of genetically mobile domains

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MEROPS: the database of proteolytic enzymes, their substrates and inhibitors

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CDD: NCBI's conserved domain database

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Suppression of cell proliferation and cytokine expression by HL‐p36, a tick salivary gland‐derived protein of Haemaphysalis longicornis

inferredcites →https://doi.org/10.1111/j.1365-2583.2008.00794.xopenalex-snapshot

Molecular characterization of the major hemelipoglycoprotein in ixodid ticks

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inferredcites →https://doi.org/10.1111/j.1538-7836.2006.01861.xopenalex-snapshot

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Effects of microplusin, a copper-chelating antimicrobial peptide, against Cryptococcus neoformans

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RESISTANCE OF DROUGHTMASTER CATTLE TO TICK INFESTATION AND BABESIOSIS

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An overview of the serpin superfamily.

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Role of the chemokine receptor CCR5-dependent host defense system in Neospora caninum infections

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Functional characterization of a cystatin from the tick Rhipicephalus haemaphysaloides

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inferredcites →https://doi.org/10.1186/s13071-017-2080-1openalex-snapshot

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inferredcites →https://doi.org/10.1186/s13071-018-3242-5openalex-snapshot

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inferredcites →https://doi.org/10.1186/s13071-018-3256-zopenalex-snapshot

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inferredcites →https://doi.org/10.1186/s13071-018-3270-1openalex-snapshot

Silencing expression of the Rhipicephalus microplus vitellogenin receptor gene blocks Babesia bovis transmission and interferes with oocyte maturation

inferredcites →https://doi.org/10.1186/s13071-019-3360-8openalex-snapshot

The mRNA expression and enzymatic activity of three enzymes during embryonic development of the hard tick Haemaphysalis longicornis

inferredcites →https://doi.org/10.1186/s13071-019-3411-1openalex-snapshot

Immunosuppressive effects of tick protein RHcyst-1 on murine bone marrow-derived dendritic cells

inferredcites →https://doi.org/10.1201/9781498712736-11openalex-snapshot

Lipocalins in Arthropoda: Diversification and Functional Explorations

inferredcites →https://doi.org/10.1242/jeb.006494openalex-snapshot

Molecular and expression analysis of a family of theAmblyomma americanumtick Lospins

inferredcites →https://doi.org/10.1242/jeb.01749openalex-snapshot

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inferredcites →https://doi.org/10.1242/jeb.107979openalex-snapshot

Dual silencing of long and short Amblyomma americanum acidic chitinase forms weakens the tick cement cone stability

inferredcites →https://doi.org/10.1242/jeb.205.18.2843openalex-snapshot

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inferredcites →https://doi.org/10.1292/jvms.63.1063openalex-snapshot

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inferredcites →https://doi.org/10.1371/journal.pntd.0001012openalex-snapshot

Collagenolytic Activities of the Major Secreted Cathepsin L Peptidases Involved in the Virulence of the Helminth Pathogen, Fasciola hepatica

inferredcites →https://doi.org/10.1371/journal.pntd.0004323openalex-snapshot

Ixodes scapularis Tick Saliva Proteins Sequentially Secreted Every 24 h during Blood Feeding

inferredcites →https://doi.org/10.1371/journal.pntd.0007660openalex-snapshot

Amblyomma americanum serpin 27 (AAS27) is a tick salivary anti-inflammatory protein secreted into the host during feeding

inferredcites →https://doi.org/10.1371/journal.pone.0000451openalex-snapshot

Immunity against Ixodes scapularis Salivary Proteins Expressed within 24 Hours of Attachment Thwarts Tick Feeding and Impairs Borrelia Transmission

inferredcites →https://doi.org/10.1371/journal.pone.0028525openalex-snapshot

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inferredcites →https://doi.org/10.1371/journal.pone.0094831openalex-snapshot

Proteomic Analysis of Cattle Tick Rhipicephalus (Boophilus) microplus Saliva: A Comparison between Partially and Fully Engorged Females

inferredcites →https://doi.org/10.1371/journal.pone.0131292openalex-snapshot

An Insight into the Sialome of the Lone Star Tick, Amblyomma americanum, with a Glimpse on Its Time Dependent Gene Expression

inferredcites →https://doi.org/10.1371/journal.pone.0170951openalex-snapshot

Insulin treatment prevents wounding associated changes in tissue and circulating neutrophil MMP-9 and NGAL in diabetic rats

inferredcites →https://doi.org/10.1371/journal.pone.0209082openalex-snapshot

Current and Future Distribution of the Lone Star Tick, Amblyomma americanum (L.) (Acari: Ixodidae) in North America

inferredcites →https://doi.org/10.1371/journal.ppat.1000062openalex-snapshot

A Cysteine Protease Is Critical for Babesia spp. Transmission in Haemaphysalis Ticks

inferredcites →https://doi.org/10.1371/journal.ppat.1003088openalex-snapshot

Make It, Take It, or Leave It: Heme Metabolism of Parasites

inferredcites →https://doi.org/10.1371/journal.ppat.1005209openalex-snapshot

Carcinogenic Parasite Secretes Growth Factor That Accelerates Wound Healing and Potentially Promotes Neoplasia

inferredcites →https://doi.org/10.2307/3276849openalex-snapshot

A Modified Method for Obtaining Tick Oral Secretion

inferredcites →https://doi.org/10.2307/3281330openalex-snapshot

Protein Changes in the Salivary Glands of the Female Lone Star Tick, Amblyomma americanum, during Feeding

inferredcites →https://doi.org/10.2307/3284095openalex-snapshot

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inferredcites →https://doi.org/10.2741/3363openalex-snapshot

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inferredcites →https://doi.org/10.3109/10409238.2015.1050550openalex-snapshot

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inferredcites →https://doi.org/10.3201/eid1101.040303openalex-snapshot

Hypersensitivity to Ticks and Lyme Disease Risk

inferredcites →https://doi.org/10.3201/eid1705.101530openalex-snapshot

Rickettsia rickettsiiTransmission by a Lone Star Tick, North Carolina

inferredcites →https://doi.org/10.3389/fcimb.2017.00199openalex-snapshot

Serine Protease Inhibitors in Ticks: An Overview of Their Role in Tick Biology and Tick-Borne Pathogen Transmission

inferredcites →https://doi.org/10.3389/fcimb.2017.00216openalex-snapshot

Protease Inhibitors in Tick Saliva: The Role of Serpins and Cystatins in Tick-host-Pathogen Interaction

inferredcites →https://doi.org/10.3389/fcimb.2017.00288openalex-snapshot

Salivary Tick Cystatin OmC2 Targets Lysosomal Cathepsins S and C in Human Dendritic Cells

inferredcites →https://doi.org/10.3389/fcimb.2017.00517openalex-snapshot

Tick-Host Range Adaptation: Changes in Protein Profiles in Unfed Adult Ixodes scapularis and Amblyomma americanum Saliva Stimulated to Feed on Different Hosts

inferredcites →https://doi.org/10.3389/fphar.2014.00115openalex-snapshot

Heme on innate immunity and inflammation

inferredcites →https://doi.org/10.3389/fpls.2018.00302openalex-snapshot

Plant Glycine-Rich Proteins in Stress Response: An Emerging, Still Prospective Story

inferredcites →https://doi.org/10.3390/molecules23112846openalex-snapshot

Heat Shock Proteins as Immunomodulants

inferredcites →https://doi.org/10.4049/jimmunol.0803282openalex-snapshot

Lipocalin 2 Is Required for Pulmonary Host Defense against Klebsiella Infection

inferredcites →https://doi.org/10.4049/jimmunol.0900075openalex-snapshot

The Immunomodulatory Action of Sialostatin L on Dendritic Cells Reveals Its Potential to Interfere with Autoimmunity

inferredcites →https://doi.org/10.4269/ajtmh.13-0209openalex-snapshot

First Detection of Heartland Virus (Bunyaviridae: Phlebovirus) from Field Collected Arthropods

inferredcites →https://doi.org/10.4269/ajtmh.1979.28.876openalex-snapshot

Resistance to Tick-Borne Francisella Tularensis by Tick-Sensitized Rabbits: Allergic Klendusity

inferredcites →https://doi.org/10.4269/ajtmh.1993.49.239openalex-snapshot

Amblyomma americanum: a Potential Vector of Human Ehrlichiosis

inferredcites →https://doi.org/10.4269/ajtmh.1998.58.780openalex-snapshot

Prevention of Borrelia burgdorferi transmission in guinea pigs by tick immunity.

inferredcites →https://doi.org/10.4269/ajtmh.2004.71.3.0700268openalex-snapshot

SHORT REPORT: DURATION OF TICK ATTACHMENT REQUIRED FOR TRANSMISSION OF POWASSAN VIRUS BY DEER TICKS

inferredcites →https://doi.org/10.5167/uzh-131237openalex-snapshot

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

inferredcites →https://doi.org/10.5169/seals-402018openalex-snapshot

Tick-Host specificity

inferredcites →https://doi.org/10.7554/elife.12318openalex-snapshot

Acquisition of exogenous haem is essential for tick reproduction

inferredcites →https://doi.org/10.7589/0090-3558-24.4.679openalex-snapshot

SUSCEPTIBILITY OF AMBLYOMMA AMERICANUM TO NATURAL AND EXPERIMENTAL INFECTIONS WITH THEILERIA CERVI

inferredcites →https://doi.org/10.7589/0090-3558-41.4.806openalex-snapshot

Theileriosis in a White-tailed Deer (Odocoileus virginianus) Fawn

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Evaluation of the Biological Function and Antimicrobial Activity of Ribosomal Protein S18 from Cattle Tick Rhipicephalus Microplus

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mRNA Vaccines Against Tick‐borne Diseases

inferred← citeshttps://doi.org/10.1007/s10493-023-00798-zopenalex-snapshot

Circulating oxidative stress and acute phase protein levels in horses infested with ticks

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Comparative genomic and proteomic analysis reveals orthogroup structured evolution of tick protease inhibitors

inferred← citeshttps://doi.org/10.1016/j.heliyon.2021.e06721openalex-snapshot

Comparative analysis of Rhipicephalus tick salivary gland and cement elementome

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Regulation of tick attachment and rapid engorgement via dopamine receptors in the Asian longhorned tick Haemaphysalis longicornis

inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2020.04.088openalex-snapshot

Amblyomma americanum serpin 41 (AAS41) inhibits inflammation by targeting chymase and chymotrypsin

inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2023.126545openalex-snapshot

ATP-sensitive inward rectifier potassium channels regulate secretion of pro-feeding salivary proteins in the lone star tick (Amblyomma americanum)

inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2026.152305openalex-snapshot

Click chemistry reveals sialylated glycoprotein biosynthesis in Ixodes ricinus ticks and tick-derived cells

inferred← citeshttps://doi.org/10.1016/j.jprot.2020.103899openalex-snapshot

Integrated analysis of sialotranscriptome and sialoproteome of the brown dog tick Rhipicephalus sanguineus (s.l.): Insights into gene expression during blood feeding

inferred← citeshttps://doi.org/10.1016/j.pt.2023.07.009openalex-snapshot

Tick extracellular vesicles in host skin immunity and pathogen transmission

inferred← citeshttps://doi.org/10.1016/j.rvsc.2021.04.013openalex-snapshot

Oxidative and local histopathological response on skin wound of horses due to Amblyomma sculptum tick parasitism

inferred← citeshttps://doi.org/10.1016/j.ttbdis.2022.102017openalex-snapshot

Immunization of guinea pigs with cement extract induces resistance against Ixodes scapularis ticks

inferred← citeshttps://doi.org/10.1016/j.ttbdis.2023.102256openalex-snapshot

Identification, structural modeling, gene expression analysis and RNAi effect of putative phospholipase A2 in the lone star tick Amblyomma americanum

inferred← citeshttps://doi.org/10.1016/j.ttbdis.2024.102333openalex-snapshot

Evaluation of the biological function of ribosomal protein S18 from cattle tick Rhipicephalus microplus

inferred← citeshttps://doi.org/10.1016/j.ttbdis.2025.102514openalex-snapshot

IxsS7: A novel biomarker for Ixodes scapularis tick bite exposure in humans

inferred← citeshttps://doi.org/10.1016/j.ttbdis.2026.102681openalex-snapshot

Predictors of tick-associated rash illness (TARI) among tick bite patients: Roles of exposure history and tick biological characteristics

inferred← citeshttps://doi.org/10.1016/j.vaccine.2020.10.087openalex-snapshot

Fractionation of tick saliva reveals proteins associated with the development of acquired resistance to Ixodes scapularis

inferred← citeshttps://doi.org/10.1016/j.vetpar.2021.109610openalex-snapshot

Ticks and antibodies: May parasite density and tick evasion influence the outcomes following immunization protocols?

inferred← citeshttps://doi.org/10.1016/j.vetpar.2023.109933openalex-snapshot

Saliva proteome of partially- and fully-engorged adult female Haemaphysalis flava ticks

inferred← citeshttps://doi.org/10.1038/s41588-022-01275-wopenalex-snapshot

A high-quality Ixodes scapularis genome advances tick science

inferred← citeshttps://doi.org/10.1038/s41598-022-24881-4openalex-snapshot

Identification and characterization of proteins that form the inner core Ixodes scapularis tick attachment cement layer

inferred← citeshttps://doi.org/10.1080/14789450.2021.2018305openalex-snapshot

Characterization of tick salivary gland and saliva alphagalactome reveals candidate alpha-gal syndrome disease biomarkers

inferred← citeshttps://doi.org/10.1111/ddg.14821openalex-snapshot

The tick and I: Parasite‐host interactions between ticks and humans

inferred← citeshttps://doi.org/10.1111/ddg.14821_gopenalex-snapshot

Die Zecke und ich: Parasiten‐Wirt‐Interaktionen zwischen Zecken und Menschen

inferred← citeshttps://doi.org/10.1111/pim.12807openalex-snapshot

Tick salivary gland transcriptomics and proteomics

inferred← citeshttps://doi.org/10.1111/pim.12808openalex-snapshot

Acquired tick resistance: The trail is hot

inferred← citeshttps://doi.org/10.1126/scitranslmed.abj9827openalex-snapshot

mRNA vaccination induces tick resistance and prevents transmission of the Lyme disease agent

inferred← citeshttps://doi.org/10.1186/s12864-021-07429-0openalex-snapshot

Borrelia burgdorferi infection modifies protein content in saliva of Ixodes scapularis nymphs

inferred← citeshttps://doi.org/10.1186/s12864-026-12666-2openalex-snapshot

Further insights into the sialome switch of Amblyomma americanum adult females

inferred← citeshttps://doi.org/10.1186/s13071-021-04671-zopenalex-snapshot

RNA-seq analysis and gene expression dynamics in the salivary glands of the argasid tick Ornithodoros erraticus along the trophogonic cycle

inferred← citeshttps://doi.org/10.1186/s13071-021-04892-2openalex-snapshot

Proteomics informed by transcriptomics for a qualitative and quantitative analysis of the sialoproteome of adult Ornithodoros moubata ticks

inferred← citeshttps://doi.org/10.1186/s13071-021-05118-1openalex-snapshot

A proteomics informed by transcriptomics insight into the proteome of Ornithodoros erraticus adult tick saliva

inferred← citeshttps://doi.org/10.1186/s13071-024-06136-5openalex-snapshot

Changes in saliva protein profile throughout Rhipicephalus microplus blood feeding

inferred← citeshttps://doi.org/10.1371/journal.pntd.0009105openalex-snapshot

Sialotranscriptomics of the argasid tick Ornithodoros moubata along the trophogonic cycle

inferred← citeshttps://doi.org/10.1371/journal.ppat.1012032openalex-snapshot

A tick saliva serpin, IxsS17 inhibits host innate immune system proteases and enhances host colonization by Lyme disease agent

inferred← citeshttps://doi.org/10.1590/0103-8478cr20230161openalex-snapshot

Vaccination against Rhipicephalusmicroplus: an alternative to chemical control?

inferred← citeshttps://doi.org/10.32469/10355/90999openalex-snapshot

Refinement of an established large-animal model to understand the tick-pathogen-host interface

inferred← citeshttps://doi.org/10.3389/fcimb.2020.563349openalex-snapshot

The Central Role of Salivary Metalloproteases in Host Acquired Resistance to Tick Feeding

inferred← citeshttps://doi.org/10.3389/fcimb.2020.574405openalex-snapshot

Quantitative Visions of Reality at the Tick-Host Interface: Biochemistry, Genomics, Proteomics, and Transcriptomics as Measures of Complete Inventories of the Tick Sialoverse

inferred← citeshttps://doi.org/10.3389/fcimb.2021.769542openalex-snapshot

Phylogenetic Analysis Indicates That Evasin-Like Proteins of Ixodid Ticks Fall Into Three Distinct Classes

inferred← citeshttps://doi.org/10.3389/fcimb.2023.1253670openalex-snapshot

Ixodes scapularis nymph saliva protein blocks host inflammation and complement-mediated killing of Lyme disease agent, Borrelia burgdorferi

inferred← citeshttps://doi.org/10.3389/fimmu.2022.844262openalex-snapshot

Tick Intrastadial Feeding and Its Role on IgE Production in the Murine Model of Alpha-gal Syndrome: The Tick “Transmission” Hypothesis

inferred← citeshttps://doi.org/10.3390/biom10040555openalex-snapshot

Tick and Host Derived Compounds Detected in the Cement Complex Substance

inferred← citeshttps://doi.org/10.3390/genes17040361openalex-snapshot

Chromosome-Scale Atlas of Ixodes scapularis Serine Protease Inhibitors

inferred← citeshttps://doi.org/10.3390/microorganisms13040795openalex-snapshot

Multi-Omics Technologies Applied to Improve Tick Research

inferred← citeshttps://doi.org/10.3390/microorganisms8111639openalex-snapshot

Mechanisms Affecting the Acquisition, Persistence and Transmission of Francisella tularensis in Ticks

inferred← citeshttps://doi.org/10.3390/pathogens12091117openalex-snapshot

Rabbits as Animal Models for Anti-Tick Vaccine Development: A Global Scenario

inferred← citeshttps://doi.org/10.3390/pathogens13070560openalex-snapshot

Recombinant Ixodes scapularis Calreticulin Binds Complement Proteins but Does Not Protect Borrelia burgdorferi from Complement Killing

inferred← citeshttps://doi.org/10.3390/pathogens15030281openalex-snapshot

Cattle Immunization with T7 Phage-Displayed Whole-Tick Antigens Reduces Amblyomma americanum Feeding Efficiency and Blocks Larval Tick Hatching

inferred← citeshttps://doi.org/10.3390/vaccines8030475openalex-snapshot

Failed Disruption of Tick Feeding, Viability, and Molting after Immunization of Mice and Sheep with Recombinant Ixodes ricinus Salivary Proteins IrSPI and IrLip1

inferred← citeshttps://doi.org/10.4269/ajtmh.20-0776openalex-snapshot

Naturally Acquired Resistance to Ixodes scapularis Elicits Partial Immunity against Other Tick Vectors in a Laboratory Host

inferred← citeshttps://doi.org/10.54034/mic.e1241openalex-snapshot

Description of human infestations by ticks in Panama and Costa Rica

inferred← citeshttps://doi.org/10.6084/m9.figshare.15153890openalex-snapshot

Additional file 5 of Proteomics informed by transcriptomics for a qualitative and quantitative analysis of the sialoproteome of adult Ornithodoros moubata ticks

inferred← citeshttps://doi.org/10.6084/m9.figshare.26673579openalex-snapshot

Additional file 1 of Changes in saliva protein profile throughout Rhipicephalus microplus blood feeding

inferred← citeshttps://doi.org/10.6084/m9.figshare.26673582openalex-snapshot

Additional file 2 of Changes in saliva protein profile throughout Rhipicephalus microplus blood feeding

inferred← citeshttps://doi.org/10.6084/m9.figshare.26673585openalex-snapshot

Additional file 3 of Changes in saliva protein profile throughout Rhipicephalus microplus blood feeding

inferred← citeshttps://doi.org/10.6084/m9.figshare.26673588openalex-snapshot

Additional file 4 of Changes in saliva protein profile throughout Rhipicephalus microplus blood feeding

inferred← citeshttps://doi.org/10.6084/m9.figshare.26673591openalex-snapshot

Additional file 5 of Changes in saliva protein profile throughout Rhipicephalus microplus blood feeding

inferred← citeshttps://doi.org/10.6084/m9.figshare.26673594openalex-snapshot

Additional file 6 of Changes in saliva protein profile throughout Rhipicephalus microplus blood feeding

inferred← citeshttps://doi.org/10.6084/m9.figshare.26673597openalex-snapshot

Additional file 7 of Changes in saliva protein profile throughout Rhipicephalus microplus blood feeding

inferred← citeshttps://doi.org/10.6084/m9.figshare.26673600openalex-snapshot

Additional file 8 of Changes in saliva protein profile throughout Rhipicephalus microplus blood feeding

inferred← citeshttps://doi.org/10.6084/m9.figshare.26673603openalex-snapshot

Additional file 9 of Changes in saliva protein profile throughout Rhipicephalus microplus blood feeding

inferred← citeshttps://doi.org/10.6084/m9.figshare.26673606openalex-snapshot

Additional file 10 of Changes in saliva protein profile throughout Rhipicephalus microplus blood feeding

inferred← citeshttps://doi.org/10.6084/m9.figshare.26673609openalex-snapshot

Additional file 11 of Changes in saliva protein profile throughout Rhipicephalus microplus blood feeding

inferred← citeshttps://doi.org/10.6084/m9.figshare.26673612openalex-snapshot

Additional file 12 of Changes in saliva protein profile throughout Rhipicephalus microplus blood feeding

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