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A Protocol for the Comprehensive Flow Cytometric Analysis of Immune Cells in Normal and Inflamed Murine Non-Lymphoid Tissues

https://doi.org/10.1371/journal.pone.0150606
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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inferredcites →https://doi.org/10.1016/s0021-9258(18)33302-7openalex-snapshot
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inferredcites →https://doi.org/10.1016/s1074-7613(03)00174-2openalex-snapshot
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inferredcites →https://doi.org/10.1038/ni.2419openalex-snapshot
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inferredcites →https://doi.org/10.1038/nri3087openalex-snapshot
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inferredcites →https://doi.org/10.1073/pnas.88.7.2835openalex-snapshot
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inferredcites →https://doi.org/10.1074/jbc.271.1.486openalex-snapshot
Molecular Cloning of F4/80, a Murine Macrophage-restricted Cell Surface Glycoprotein with Homology to the G-protein-linked Transmembrane 7 Hormone Receptor Family
inferredcites →https://doi.org/10.1084/jem.170.6.1959openalex-snapshot
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inferredcites →https://doi.org/10.1084/jem.176.1.287openalex-snapshot
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inferredcites →https://doi.org/10.1084/jem.20080201openalex-snapshot
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inferredcites →https://doi.org/10.1084/jem.20120340openalex-snapshot
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inferredcites →https://doi.org/10.1128/mcb.12.3.954openalex-snapshot
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inferredcites →https://doi.org/10.1128/mcb.20.11.4106-4114.2000openalex-snapshot
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inferredcites →https://doi.org/10.1164/rccm.201009-1431ocopenalex-snapshot
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inferredcites →https://doi.org/10.1165/rcmb.2012-0366maopenalex-snapshot
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inferredcites →https://doi.org/10.1165/rcmb.2013-0086maopenalex-snapshot
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inferredcites →https://doi.org/10.1172/jci116498openalex-snapshot
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inferredcites →https://doi.org/10.1182/blood-2008-10-187179openalex-snapshot
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inferredcites →https://doi.org/10.1242/dev.127.11.2269openalex-snapshot
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inferredcites →https://doi.org/10.1371/journal.pone.0033297openalex-snapshot
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inferredcites →https://doi.org/10.3389/fimmu.2015.00435openalex-snapshot
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inferredcites →https://doi.org/10.4049/jimmunol.1102744openalex-snapshot
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inferredcites →https://doi.org/10.4049/jimmunol.1200604openalex-snapshot
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inferredcites →https://doi.org/10.4049/jimmunol.158.6.2517openalex-snapshot
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inferredcites →https://doi.org/10.4049/jimmunol.180.4.2562openalex-snapshot
CCR2+ Monocyte-Derived Dendritic Cells and Exudate Macrophages Produce Influenza-Induced Pulmonary Immune Pathology and Mortality
inferredcites →https://doi.org/10.4049/jimmunol.181.9.5829openalex-snapshot
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What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1038/s41467-017-01829-1openalex-snapshot
The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis
inferred← citeshttps://doi.org/10.1038/s41467-018-03001-9openalex-snapshot
Sustained micellar delivery via inducible transitions in nanostructure morphology
inferred← citeshttps://doi.org/10.1038/s41467-018-05899-7openalex-snapshot
HIV-1 intron-containing RNA expression induces innate immune activation and T cell dysfunction
inferred← citeshttps://doi.org/10.1038/s41467-019-10156-6openalex-snapshot
CD200R deletion promotes a neutrophil niche for Francisella tularensis and increases infectious burden and mortality
inferred← citeshttps://doi.org/10.1038/s41467-019-10424-5openalex-snapshot
CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer
inferred← citeshttps://doi.org/10.1038/s41467-020-16890-6openalex-snapshot
Chronic circadian disruption modulates breast cancer stemness and immune microenvironment to drive metastasis in mice
inferred← citeshttps://doi.org/10.1038/s41467-020-17704-5openalex-snapshot
Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types
inferred← citeshttps://doi.org/10.1038/s41467-020-20886-7openalex-snapshot
Surface chemistry-mediated modulation of adsorbed albumin folding state specifies nanocarrier clearance by distinct macrophage subsets
inferred← citeshttps://doi.org/10.1038/s41467-021-24797-zopenalex-snapshot
Colonization of dermal arterioles by Neisseria meningitidis provides a safe haven from neutrophils
inferred← citeshttps://doi.org/10.1038/s41467-021-26834-3openalex-snapshot
Mesenchymal stromal cell apoptosis is required for their therapeutic function
inferred← citeshttps://doi.org/10.1038/s41467-021-27860-xopenalex-snapshot
Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice
inferred← citeshttps://doi.org/10.1038/s41467-023-40545-xopenalex-snapshot
NAD(H) homeostasis underlies host protection mediated by glycolytic myeloid cells in tuberculosis
inferred← citeshttps://doi.org/10.1038/s41467-026-68788-4openalex-snapshot
Collagen binding adhesin restricts Staphylococcus aureus skin infection
inferred← citeshttps://doi.org/10.1038/s41541-025-01209-7openalex-snapshot
Immunogenicity and protective efficacy of an intranasal neuraminidase-based influenza vaccine with bacterial cell membrane-derived adjuvants
inferred← citeshttps://doi.org/10.1038/s41556-020-0505-0openalex-snapshot
Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling
inferred← citeshttps://doi.org/10.1038/s41564-023-01354-6openalex-snapshot
Autophagy restricts Mycobacterium tuberculosis during acute infection in mice
inferred← citeshttps://doi.org/10.1038/s41565-021-01048-2openalex-snapshot
Subcutaneous nanotherapy repurposes the immunosuppressive mechanism of rapamycin to enhance allogeneic islet graft viability
inferred← citeshttps://doi.org/10.1038/s41586-023-06508-4openalex-snapshot
Endothelial sensing of AHR ligands regulates intestinal homeostasis
inferred← citeshttps://doi.org/10.1038/s41586-025-09332-0openalex-snapshot
Respiratory viral infections awaken metastatic breast cancer cells in lungs
inferred← citeshttps://doi.org/10.1038/s41592-019-0355-5openalex-snapshot
Cell composition analysis of bulk genomics using single-cell data
inferred← citeshttps://doi.org/10.1038/s41598-017-11313-xopenalex-snapshot
Pandemic 2009 H1N1 Influenza Venus reporter virus reveals broad diversity of MHC class II-positive antigen-bearing cells following infection in vivo
inferred← citeshttps://doi.org/10.1038/s41598-018-34731-xopenalex-snapshot
Deciphering the immune microenvironment of a tissue by digital imaging and cognition network
inferred← citeshttps://doi.org/10.1038/s41598-019-41141-0openalex-snapshot
Molecular profiling of resident and infiltrating mononuclear phagocytes during rapid adult retinal degeneration using single-cell RNA sequencing
inferred← citeshttps://doi.org/10.1038/s41598-020-62735-zopenalex-snapshot
Distinct inactivated bacterial-based immune modulators vary in their therapeutic efficacies for treating disease based on the organ site of pathology
inferred← citeshttps://doi.org/10.1038/s41598-020-79260-8openalex-snapshot
The novel rexinoid MSU-42011 is effective for the treatment of preclinical Kras-driven lung cancer
inferred← citeshttps://doi.org/10.1038/s41598-021-82752-wopenalex-snapshot
Integrins mediate placental extracellular vesicle trafficking to lung and liver in vivo
inferred← citeshttps://doi.org/10.1038/s41598-021-88291-8openalex-snapshot
Subunit vaccine protects against a clinical isolate of Mycobacterium avium in wild type and immunocompromised mouse models
inferred← citeshttps://doi.org/10.1038/s41598-021-92784-xopenalex-snapshot
A flow cytometry approach reveals heterogeneity in conventional subsets of murine renal mononuclear phagocytes
inferred← citeshttps://doi.org/10.1038/s41598-022-11435-xopenalex-snapshot
Sotatercept analog suppresses inflammation to reverse experimental pulmonary arterial hypertension
inferred← citeshttps://doi.org/10.1038/s41598-022-12597-4openalex-snapshot
Initial TK-deficient HSV-1 infection in the lip alters contralateral lip challenge immune dynamics
inferred← citeshttps://doi.org/10.1038/s41598-023-49280-1openalex-snapshot
Associations of tissue damage induced inflammatory plasticity in masseter muscle with the resolution of chronic myalgia
inferred← citeshttps://doi.org/10.1038/s41598-024-68485-6openalex-snapshot
Degenerative and regenerative peripheral processes are associated with persistent painful chemotherapy-induced neuropathies in males and females
inferred← citeshttps://doi.org/10.1038/s42003-019-0425-3openalex-snapshot
Intravital imaging allows real-time characterization of tissue resident eosinophils
inferred← citeshttps://doi.org/10.1038/s42003-019-0618-9openalex-snapshot
Single-cell RNA-sequencing analysis of estrogen- and endocrine-disrupting chemical-induced reorganization of mouse mammary gland
inferred← citeshttps://doi.org/10.1038/s42003-020-1018-xopenalex-snapshot
In vivo dual RNA-seq reveals that neutrophil recruitment underlies differential tissue tropism of Streptococcus pneumoniae
inferred← citeshttps://doi.org/10.1038/s42003-022-04339-zopenalex-snapshot
Neutrophil trafficking to the site of infection requires Cpt1a-dependent fatty acid β-oxidation
inferred← citeshttps://doi.org/10.1038/s42255-021-00402-xopenalex-snapshot
Pre-operative exercise therapy triggers anti-inflammatory trained immunity of Kupffer cells through metabolic reprogramming
inferred← citeshttps://doi.org/10.1038/srep40508openalex-snapshot
Inference of immune cell composition on the expression profiles of mouse tissue
inferred← citeshttps://doi.org/10.1039/d0nr08806dopenalex-snapshot
A hydrogel-based implantable multidrug antitubercular formulation outperforms oral delivery
inferred← citeshttps://doi.org/10.1042/bsr20200538openalex-snapshot
Profiles of immune infiltration and its relevance to survival outcome in meningiomas
inferred← citeshttps://doi.org/10.1042/cs20200249openalex-snapshot
TRIF/miR-34a mediates aldosterone-induced cardiac inflammation and remodeling
inferred← citeshttps://doi.org/10.1073/pnas.2121098119openalex-snapshot
Nanoparticle targeting of de novo profibrotic macrophages mitigates lung fibrosis
inferred← citeshttps://doi.org/10.1073/pnas.2202012119openalex-snapshot
Caspase-4/11 exacerbates disease severity in SARS–CoV-2 infection by promoting inflammation and immunothrombosis
inferred← citeshttps://doi.org/10.1073/pnas.2216458120openalex-snapshot
Molecular imaging of chemokine-like receptor 1 (CMKLR1) in experimental acute lung injury
inferred← citeshttps://doi.org/10.1080/01902148.2018.1432721openalex-snapshot
Improved protocol for simultaneous analysis of leukocyte subsets and epithelial cells from murine and human lung
inferred← citeshttps://doi.org/10.1080/17476348.2020.1776117openalex-snapshot
Immunopathogenesis and therapeutic potential of macrophage influx in diffuse parenchymal lung diseases
inferred← citeshttps://doi.org/10.1080/19420862.2019.1602459openalex-snapshot
Neonatal Fc receptor expression in macrophages is indispensable for IgG homeostasis
inferred← citeshttps://doi.org/10.1080/2162402x.2017.1398875openalex-snapshot
Harnessing innate lung anti-cancer effector functions with a novel bacterial-derived immunotherapy
inferred← citeshttps://doi.org/10.1080/2162402x.2024.2429846openalex-snapshot
Systemic administration of a viral nanoparticle neoadjuvant prevents lung metastasis development through emergency myelopoiesis
inferred← citeshttps://doi.org/10.1080/21645515.2022.2055945openalex-snapshot
Human placental hematopoietic stem cell derived natural killer cells (CYNK-001) mediate protection against influenza a viral infection
inferred← citeshttps://doi.org/10.1084/jem.20181468openalex-snapshot
Neutrophils instruct homeostatic and pathological states in naive tissues
inferred← citeshttps://doi.org/10.1084/jem.20220741openalex-snapshot
Immune-interacting lymphatic endothelial subtype at capillary terminals drives lymphatic malformation
inferred← citeshttps://doi.org/10.1084/jem.20221472openalex-snapshot
Phagocytosis increases an oxidative metabolic and immune suppressive signature in tumor macrophages
inferred← citeshttps://doi.org/10.1093/bioinformatics/btz321openalex-snapshot
A statistical simulator scDesign for rational scRNA-seq experimental design
inferred← citeshttps://doi.org/10.1093/bioinformatics/btz672openalex-snapshot
Tissue-specific deconvolution of immune cell composition by integrating bulk and single-cell transcriptomes
inferred← citeshttps://doi.org/10.1093/cvr/cvaa067openalex-snapshot
Sectm1a deficiency aggravates inflammation-triggered cardiac dysfunction through disruption of LXRα signalling in macrophages
inferred← citeshttps://doi.org/10.1093/cvr/cvab192openalex-snapshot
Non-coding RNAs in cardiac inflammation: key drivers in the pathophysiology of heart failure
inferred← citeshttps://doi.org/10.1093/cvr/cvab336openalex-snapshot
Loss of myeloid Bmal1 exacerbates hypertensive vascular remodelling through interaction with STAT6 in mice
inferred← citeshttps://doi.org/10.1093/cvr/cvy304openalex-snapshot
Innate immunity as a target for acute cardioprotection
inferred← citeshttps://doi.org/10.1093/discim/kyaf018openalex-snapshot
Fluoroquinolones directly drive mitochondrial hyperpolarization and modulate iNOS expression in monocyte-derived macrophage populations
inferred← citeshttps://doi.org/10.1093/immhor/vlaf026openalex-snapshot
Interleukin-27–producing cells in gram-negative neonatal sepsis display diverse phenotypes and functions in the liver
inferred← citeshttps://doi.org/10.1093/infdis/jiaf361openalex-snapshot
Inflammatory Macrophages Associate With Tissue Injury and Fibrosis in a Mouse Model of Tuberculosis
inferred← citeshttps://doi.org/10.1093/jleuko/qiad047openalex-snapshot
Myeloid Bmal1 deletion suppresses the house dust mite–induced chronic lung allergy
inferred← citeshttps://doi.org/10.1093/toxsci/kfag004openalex-snapshot
Aryl hydrocarbon receptor activation alters emergency hematopoiesis during influenza A virus infection
inferred← citeshttps://doi.org/10.1093/toxsci/kfz056openalex-snapshot
Sex Modifies Acute Ozone-Mediated Airway Physiologic Responses
inferred← citeshttps://doi.org/10.1096/fj.202100495ropenalex-snapshot
Ablation of PDE4B protects from Pseudomonas aeruginosa ‐induced acute lung injury in mice by ameliorating the cytostorm and associated hypothermia
inferred← citeshttps://doi.org/10.1096/fj.202300757ropenalex-snapshot
Lethal eosinophilic crystalline pneumonia in mice expressing a stabilized Csf2 mRNA
inferred← citeshttps://doi.org/10.1096/fj.202402865ropenalex-snapshot
ALX / FPR2 Contributes to Serum Amyloid A‐Induced Lung Neutrophil Recruitment Following Acute Ozone Exposure
inferred← citeshttps://doi.org/10.1101/2021.03.04.430128openalex-snapshot
The mRNA-LNP platform’s lipid nanoparticle component used in preclinical vaccine studies is highly inflammatory
inferred← citeshttps://doi.org/10.1101/2022.05.29.493868openalex-snapshot
A novel approach to single cell analysis to reveal intrinsic differences in immune marker expression in unstimulated macrophages from BALB/c and C57BL/6 mouse strains
inferred← citeshttps://doi.org/10.1101/2022.09.11.507472openalex-snapshot
NAD(H) homeostasis is essential for host protection mediated by glycolytic myeloid cells in tuberculosis
inferred← citeshttps://doi.org/10.1101/2023.02.16.528861openalex-snapshot
Allergic Asthma Responses Are Dependent on Macrophage Ontogeny
inferred← citeshttps://doi.org/10.1101/2023.04.21.537828openalex-snapshot
Association of inflammation and tissue damage induced biological processes in masseter muscle with the resolution of chronic myalgia
inferred← citeshttps://doi.org/10.1101/2023.10.03.560704openalex-snapshot
An Enzyme-Free, Cold-Process Acoustic Method for Gentle and Effective Tissue Dissociation
inferred← citeshttps://doi.org/10.1101/2023.11.08.566238openalex-snapshot
A BCG Skin Challenge Model for Assessing TB Vaccines
inferred← citeshttps://doi.org/10.1101/2024.06.04.597479openalex-snapshot
A mouse model of TB-associated lung fibrosis reveals persistent inflammatory macrophage populations during treatment
inferred← citeshttps://doi.org/10.1101/2024.10.07.617070openalex-snapshot
Antibody-Fab and -Fc features promote Mycobacterium tuberculosis restriction
inferred← citeshttps://doi.org/10.1101/2025.01.20.633951openalex-snapshot
Aging directs the differential evolution of KRAS-driven lung adenocarcinoma
inferred← citeshttps://doi.org/10.1101/2025.01.23.634531openalex-snapshot
Reprogramming of alveolar macrophages by intestinal segmented filamentous bacteria protects mice from lethal bacterial pneumoniae following influenza infection
inferred← citeshttps://doi.org/10.1101/2025.01.27.634989openalex-snapshot
Ex vivo modelling of lung tissue resident antimicrobial responses
inferred← citeshttps://doi.org/10.1101/2025.01.31.635552openalex-snapshot
Humanized Bone Marrow-Liver-Thymus Mice for Studying HIV-1 Persistence in Liver and Lung CD4+ T and Myeloid Cell Subsets during Antiretroviral Therapy
inferred← citeshttps://doi.org/10.1101/2025.02.26.640278openalex-snapshot
Immunogenicity and protective efficacy of an intranasal neuraminidase-based influenza virus vaccine adjuvanted with bacterial cell membrane-derived adjuvants
inferred← citeshttps://doi.org/10.1101/612598openalex-snapshot
The right microbial stimulus can direct innate immune effector cells to specific organ sites to clear pathology
inferred← citeshttps://doi.org/10.1111/bph.14521openalex-snapshot
Seselin ameliorates inflammation via targeting Jak2 to suppress the proinflammatory phenotype of macrophages
inferred← citeshttps://doi.org/10.1111/bph.70656openalex-snapshot
Alamandine/MrgD pathway modulates gut–bone marrow axis in ageing
inferred← citeshttps://doi.org/10.1111/imr.13050openalex-snapshot
Imaging dendritic cell functions*
inferred← citeshttps://doi.org/10.1111/trf.16191openalex-snapshot
Autoantigen presentation by splenic dendritic cells is required for RBC ‐specific autoimmunity
inferred← citeshttps://doi.org/10.1124/dmd.121.000460openalex-snapshot
Mathematical Models to Characterize the Absorption, Distribution, Metabolism, and Excretion of Protein Therapeutics
inferred← citeshttps://doi.org/10.1126/sciadv.abd9436openalex-snapshot
PD-L1 + neutrophils contribute to injury-induced infection susceptibility
inferred← citeshttps://doi.org/10.1126/sciadv.aeh6480openalex-snapshot
Long-term immunoprophylaxis by TLR9 ligand mediates macrophage-ILC cross-talk against respiratory viral infection
inferred← citeshttps://doi.org/10.1126/sciimmunol.aba7350openalex-snapshot
Functional heterogeneity of alveolar macrophage population based on expression of CXCL2
inferred← citeshttps://doi.org/10.1126/sciimmunol.adt8858openalex-snapshot
Segmented filamentous bacteria reprogramming of alveolar macrophages limits postinfluenza bacterial pneumonia
inferred← citeshttps://doi.org/10.1126/sciimmunol.adx1135openalex-snapshot
Local activation of mutant RIG-I by short noncoding Y-RNA in the kidney triggers lethal nephritis
inferred← citeshttps://doi.org/10.1126/scitranslmed.aau2814openalex-snapshot
Calpain 9 as a therapeutic target in TGFβ-induced mesenchymal transition and fibrosis
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