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Clumping factor B is an important virulence factor during Staphylococcus aureus skin infection and a promising vaccine target
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1001/archinte.168.14.1585openalex-snapshot
National Trends in Ambulatory Visits and Antibiotic Prescribing for Skin and Soft-Tissue Infections
inferredcites →https://doi.org/10.1002/eji.201242372openalex-snapshot
The vaccine adjuvant alum inhibits IL ‐12 by promoting PI 3 kinase signaling while chitosan does not inhibit IL ‐12 and enhances T h1 and T h17 responses
inferredcites →https://doi.org/10.1016/0092-8674(90)90073-nopenalex-snapshot
Identification of a major keratinocyte cell envelope protein, loricrin
inferredcites →https://doi.org/10.1016/j.bbamem.2006.11.023openalex-snapshot
New arrangement of proteins and lipids in the stratum corneum cornified envelope
inferredcites →https://doi.org/10.1016/j.ebiom.2016.09.015openalex-snapshot
Bacterial Abscess Formation Is Controlled by the Stringent Stress Response and Can Be Targeted Therapeutically
inferredcites →https://doi.org/10.1016/j.immuni.2008.11.009openalex-snapshot
Differential Roles of Interleukin-17A and -17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses
inferredcites →https://doi.org/10.1016/j.jaci.2016.07.001openalex-snapshot
IL-22 derived from γδ T cells restricts Staphylococcus aureus infection of mechanically injured skin
inferredcites →https://doi.org/10.1016/j.jconrel.2016.05.001openalex-snapshot
A novel adjuvanted capsule based strategy for oral vaccination against infectious diarrhoeal pathogens
inferredcites →https://doi.org/10.1016/s0002-9440(10)64826-2openalex-snapshot
Facilitated Wound Healing by Activation of the Transglutaminase 1 Gene
inferredcites →https://doi.org/10.1038/35047123openalex-snapshot
A Toll-like receptor recognizes bacterial DNA
inferredcites →https://doi.org/10.1038/mi.2016.24openalex-snapshot
Interleukin-22 regulates antimicrobial peptide expression and keratinocyte differentiation to control Staphylococcus aureus colonization of the nasal mucosa
inferredcites →https://doi.org/10.1038/nri3010openalex-snapshot
Immunity against Staphylococcus aureus cutaneous infections
inferredcites →https://doi.org/10.1038/nrmicro3161openalex-snapshot
Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus
inferredcites →https://doi.org/10.1046/j.1365-2958.1998.01050.xopenalex-snapshot
Clumping factor B (ClfB), a new surface‐located fibrinogen‐binding adhesin of Staphylococcus aureus
inferredcites →https://doi.org/10.1056/nejmra1212788openalex-snapshot
Management of Skin Abscesses in the Era of Methicillin-Resistant Staphylococcus aureus
inferredcites →https://doi.org/10.1073/pnas.0606863103openalex-snapshot
Vaccine assembly from surface proteins of Staphylococcus aureus
inferredcites →https://doi.org/10.1073/pnas.080520697openalex-snapshot
Staphylococcus aureus sortase mutants defective in the display of surface proteins and in the pathogenesis of animal infections
inferredcites →https://doi.org/10.1073/pnas.1415610111openalex-snapshot
Mechanisms of NDV-3 vaccine efficacy in MRSA skin versus invasive infection
inferredcites →https://doi.org/10.1074/jbc.m106741200openalex-snapshot
Structural Organization of the Fibrinogen-binding Region of the Clumping Factor B MSCRAMM of Staphylococcus aureus
inferredcites →https://doi.org/10.1074/jbc.m109.062208openalex-snapshot
Molecular Characterization of the Interaction of Staphylococcal Microbial Surface Components Recognizing Adhesive Matrix Molecules (MSCRAMM) ClfA and Fbl with Fibrinogen
inferredcites →https://doi.org/10.1074/jbc.m408713200openalex-snapshot
Clumping Factor B, a Fibrinogen-binding MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules) Adhesin of Staphylococcus aureus, Also Binds to the Tail Region of Type I Cytokeratin 10
inferredcites →https://doi.org/10.1083/jcb.151.2.389openalex-snapshot
Lessons from Loricrin-Deficient Mice
inferredcites →https://doi.org/10.1084/jem.20061308openalex-snapshot
Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
inferredcites →https://doi.org/10.1093/infdis/jix290openalex-snapshot
Immunotherapy Targeting Adenosine Synthase A Decreases Severity of Staphylococcus aureus Infection in Mouse Model
inferredcites →https://doi.org/10.1096/fj.09-135467openalex-snapshot
Genetic requirements for Staphylococcus aureus abscess formation and persistence in host tissues
inferredcites →https://doi.org/10.1099/mic.0.2007/010868-0openalex-snapshot
Identification of the Staphylococcus aureus MSCRAMM clumping factor B (ClfB) binding site in the αC-domain of human fibrinogen
inferredcites →https://doi.org/10.1111/apm.12295openalex-snapshot
Surface proteins ofStaphylococcus aureusplay an important role in experimental skin infection
inferredcites →https://doi.org/10.1111/j.0022-202x.2004.23473.xopenalex-snapshot
An In Vivo Model of Wound Healing in Genetically Modified Skin-Humanized Mice
inferredcites →https://doi.org/10.1111/j.1365-2567.2004.01849.xopenalex-snapshot
Interferon‐γ activation of polymorphonuclear neutrophil function
inferredcites →https://doi.org/10.1111/j.1365-2672.2006.03127.xopenalex-snapshot
Optimization of electroporation-mediated transformation: Staphylococcus carnosus as model organism
inferredcites →https://doi.org/10.1111/j.1432-1033.1992.tb16740.xopenalex-snapshot
Genetic analysis of epidermin biosynthetic genes and epidermin‐negative mutants of Staphylococcus epidermidis
inferredcites →https://doi.org/10.1128/cmr.00081-09openalex-snapshot
Community-Associated Methicillin-Resistant Staphylococcus aureus : Epidemiology and Clinical Consequences of an Emerging Epidemic
inferredcites →https://doi.org/10.1128/iai.00549-17openalex-snapshot
The Staphylococcus aureus Cell Wall-Anchored Protein Clumping Factor A Is an Important T Cell Antigen
inferredcites →https://doi.org/10.1128/iai.00994-16openalex-snapshot
Clumping Factor B Promotes Adherence of Staphylococcus aureus to Corneocytes in Atopic Dermatitis
inferredcites →https://doi.org/10.1128/iai.01061-15openalex-snapshot
Nonredundant Roles of Interleukin-17A (IL-17A) and IL-22 in Murine Host Defense against Cutaneous and Hematogenous Infection Due to Methicillin-Resistant Staphylococcus aureus
inferredcites →https://doi.org/10.1128/iai.02951-14openalex-snapshot
Targeting Surface Protein SasX by Active and Passive Vaccination To Reduce Staphylococcus aureus Colonization and Infection
inferredcites →https://doi.org/10.1128/iai.74.4.2145-2153.2006openalex-snapshot
Immunization with Staphylococcus aureus Clumping Factor B, a Major Determinant in Nasal Carriage, Reduces Nasal Colonization in a Murine Model
inferredcites →https://doi.org/10.1128/mbio.00277-11openalex-snapshot
Transforming the Untransformable: Application of Direct Transformation To Manipulate Genetically Staphylococcus aureus and Staphylococcus epidermidis
inferredcites →https://doi.org/10.1128/mbio.00308-15openalex-snapshot
Complete Bypass of Restriction Systems for Major Staphylococcus aureus Lineages
inferredcites →https://doi.org/10.1128/mbio.02232-15openalex-snapshot
Preclinical Efficacy of Clumping Factor A in Prevention of Staphylococcus aureus Infection
inferredcites →https://doi.org/10.1172/jci40891openalex-snapshot
IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice
inferredcites →https://doi.org/10.1186/1471-2180-10-173openalex-snapshot
Genetic variation in Staphylococcus aureus surface and immune evasion genes is lineage associated: implications for vaccine design and host-pathogen interactions
inferredcites →https://doi.org/10.1242/jcs.107.2.693openalex-snapshot
Protein composition of cornified cell envelopes of epidermal keratinocytes
inferredcites →https://doi.org/10.1371/journal.pmed.0050017openalex-snapshot
Key Role for Clumping Factor B in Staphylococcus aureus Nasal Colonization of Humans
inferredcites →https://doi.org/10.1371/journal.ppat.1000159openalex-snapshot
Interleukin-17A Mediates Acquired Immunity to Pneumococcal Colonization
inferredcites →https://doi.org/10.1371/journal.ppat.1003092openalex-snapshot
Nasal Colonisation by Staphylococcus aureus Depends upon Clumping Factor B Binding to the Squamous Epithelial Cell Envelope Protein Loricrin
inferredcites →https://doi.org/10.1371/journal.ppat.1003264openalex-snapshot
Relative Contribution of Th1 and Th17 Cells in Adaptive Immunity to Bordetella pertussis: Towards the Rational Design of an Improved Acellular Pertussis Vaccine
inferredcites →https://doi.org/10.1371/journal.ppat.1005226openalex-snapshot
Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection
inferredcites →https://doi.org/10.3201/eid1211.060190openalex-snapshot
Staphylococcus aureus–associated Skin and Soft Tissue Infections in Ambulatory Care
inferredcites →https://doi.org/10.4049/jimmunol.1002794openalex-snapshot
Staphylococcus aureus Biofilms Prevent Macrophage Phagocytosis and Attenuate Inflammation In Vivo
inferredcites →https://doi.org/10.4049/jimmunol.173.5.3482openalex-snapshot
IL-17 Markedly Up-Regulates β-Defensin-2 Expression in Human Airway Epithelium via JAK and NF-κB Signaling Pathways
inferredcites →https://doi.org/10.4049/jimmunol.181.2.1323openalex-snapshot
IFN-γ Regulated Chemokine Production Determines the Outcome of Staphylococcus aureus Infection
inferredcites →https://doi.org/10.4161/hv.25182openalex-snapshot
Will there ever be a universalStaphylococcus aureusvaccine?
inferredcites →https://doi.org/10.4161/hv.7.0.14562openalex-snapshot
Challenges for the evaluation ofStaphylococcus aureusprotein based vaccines: Monitoring antigenic diversity
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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In Silico Identification of the B-Cell and T-Cell Epitopes of the Antigenic Proteins of Staphylococcus aureus for Potential Vaccines
inferred← citeshttps://doi.org/10.1007/978-981-99-8799-3_8openalex-snapshot
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Cell Wall-Anchored Surface Proteins of Staphylococcus aureus
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Integrated Genome-Wide Association Study and Machine Learning Approach for Characterizing the Determinants of Biofilm Formation in Staphylococcus aureus
inferred← citeshttps://doi.org/10.1016/j.bbadis.2019.07.004openalex-snapshot
The good side of inflammation: Staphylococcus aureus proteins SpA and Sbi contribute to proper abscess formation and wound healing during skin and soft tissue infections
inferred← citeshttps://doi.org/10.1016/j.chom.2022.12.003openalex-snapshot
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Genomic analysis of Staphylococcus aureus isolates from bacteremia reveals genetic features associated with the COVID-19 pandemic
inferred← citeshttps://doi.org/10.1016/j.isci.2026.116828openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.it.2020.11.005openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.micpath.2021.105171openalex-snapshot
B and T cell epitope-based peptides predicted from clumping factor protein of Staphylococcus aureus as vaccine targets
inferred← citeshttps://doi.org/10.1016/j.micpath.2025.107685openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.micres.2024.127703openalex-snapshot
Contribution of staphylococcal virulence factors in the pathogenesis of thrombosis
inferred← citeshttps://doi.org/10.1016/j.tim.2019.06.007openalex-snapshot
The MSCRAMM Family of Cell-Wall-Anchored Surface Proteins of Gram-Positive Cocci
inferred← citeshttps://doi.org/10.1016/s1166-8598(21)42881-4openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acs.jproteome.4c01018openalex-snapshot
γ Irradiation Alters the Staphylococcus aureus Proteome and Enhances Pathogenicity
inferred← citeshttps://doi.org/10.1021/acsinfecdis.0c00822openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acsinfecdis.9b00193openalex-snapshot
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