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ApoE4-Induced Cholesterol Dysregulation and Its Brain Cell Type-Specific Implications in the Pathogenesis of Alzheimer's Disease.
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1001/jamaneurol.2016.3232openalex-snapshot
Association of Amyloid Pathology With Myelin Alteration in Preclinical Alzheimer Disease
inferredcites →https://doi.org/10.1001/jamaneurol.2019.0648openalex-snapshot
Association of Early-Onset Alzheimer Disease With Elevated Low-Density Lipoprotein Cholesterol Levels and Rare Genetic Coding Variants of APOB
inferredcites →https://doi.org/10.1002/1531-8249(200006)47:6<739::aid-ana6>3.0.co;2-8openalex-snapshot
Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model
inferredcites →https://doi.org/10.1002/glia.22423openalex-snapshot
Regulation of microglia activation and deactivation by nuclear receptors
inferredcites →https://doi.org/10.1002/glia.23120openalex-snapshot
Astrocyte lipid metabolism is critical for synapse development and function in vivo
inferredcites →https://doi.org/10.1016/j.abb.2013.06.015openalex-snapshot
Cholesterol load of microglia: Contribution of membrane architecture changes to neurotoxic power?
inferredcites →https://doi.org/10.1016/j.bbalip.2010.05.010openalex-snapshot
Clathrin-dependent APP endocytosis and Aβ secretion are highly sensitive to the level of plasma membrane cholesterol
inferredcites →https://doi.org/10.1016/j.biopsych.2014.05.006openalex-snapshot
Alzheimer’s Disease Risk Genes and Mechanisms of Disease Pathogenesis
inferredcites →https://doi.org/10.1016/j.bpj.2017.10.017openalex-snapshot
Computational Lipidomics of the Neuronal Plasma Membrane
inferredcites →https://doi.org/10.1016/j.cell.2015.12.056openalex-snapshot
The Cellular Phase of Alzheimer’s Disease
inferredcites →https://doi.org/10.1016/j.cell.2016.12.044openalex-snapshot
ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion
inferredcites →https://doi.org/10.1016/j.cell.2017.05.018openalex-snapshot
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
inferredcites →https://doi.org/10.1016/j.cell.2018.05.003openalex-snapshot
Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration
inferredcites →https://doi.org/10.1016/j.cell.2022.05.017openalex-snapshot
Cholesterol and matrisome pathways dysregulated in astrocytes and microglia
inferredcites →https://doi.org/10.1016/j.celrep.2017.09.039openalex-snapshot
Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution
inferredcites →https://doi.org/10.1016/j.cmet.2019.06.005openalex-snapshot
A Breakdown in Metabolic Reprogramming Causes Microglia Dysfunction in Alzheimer's Disease
inferredcites →https://doi.org/10.1016/j.immuni.2017.08.008openalex-snapshot
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
inferredcites →https://doi.org/10.1016/j.neulet.2017.02.007openalex-snapshot
Alterations of myelin morphology and oligodendrocyte development in early stage of Alzheimer’s disease mouse model
inferredcites →https://doi.org/10.1016/j.neuron.2015.11.013openalex-snapshot
Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse
inferredcites →https://doi.org/10.1016/j.neuron.2017.03.042openalex-snapshot
iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases
inferredcites →https://doi.org/10.1016/j.neuron.2017.11.013openalex-snapshot
ApoE4 Accelerates Early Seeding of Amyloid Pathology
inferredcites →https://doi.org/10.1016/j.neuron.2018.05.008openalex-snapshot
APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types
inferredcites →https://doi.org/10.1016/j.plipres.2011.06.002openalex-snapshot
Cholesterol metabolism in neurons and astrocytes
inferredcites →https://doi.org/10.1016/j.tem.2016.03.018openalex-snapshot
LXR Regulation of Brain Cholesterol: From Development to Disease
inferredcites →https://doi.org/10.1016/j.tibs.2006.06.008openalex-snapshot
Apolipoprotein E structure: insights into function
inferredcites →https://doi.org/10.1038/nature11087openalex-snapshot
Apolipoprotein E controls cerebrovascular integrity via cyclophilin A
inferredcites →https://doi.org/10.1038/nature20412openalex-snapshot
The road to restoring neural circuits for the treatment of Alzheimer's disease
inferredcites →https://doi.org/10.1038/nature24016openalex-snapshot
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy
inferredcites →https://doi.org/10.1038/ng.2802openalex-snapshot
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
inferredcites →https://doi.org/10.1038/ng1197-263openalex-snapshot
Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition
inferredcites →https://doi.org/10.1038/nm.4189openalex-snapshot
Efficient derivation of microglia-like cells from human pluripotent stem cells
inferredcites →https://doi.org/10.1038/nm1058openalex-snapshot
Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-β peptides
inferredcites →https://doi.org/10.1038/nn.2583openalex-snapshot
Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks
inferredcites →https://doi.org/10.1038/nn.4534openalex-snapshot
Differentiation of human and murine induced pluripotent stem cells to microglia-like cells
inferredcites →https://doi.org/10.1038/nn1426openalex-snapshot
High cholesterol level is essential for myelin membrane growth
inferredcites →https://doi.org/10.1038/nrn3012openalex-snapshot
Linking lipids to Alzheimer's disease: cholesterol and beyond
inferredcites →https://doi.org/10.1038/nrneurol.2012.263openalex-snapshot
Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
inferredcites →https://doi.org/10.1038/s41467-017-01444-0openalex-snapshot
Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer’s disease-like pathology
inferredcites →https://doi.org/10.1038/s41586-019-1195-2openalex-snapshot
Single-cell transcriptomic analysis of Alzheimer’s disease
inferredcites →https://doi.org/10.1038/s41588-019-0358-2openalex-snapshot
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
inferredcites →https://doi.org/10.1038/s41593-018-0296-9openalex-snapshot
Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE
inferredcites →https://doi.org/10.1038/s41598-018-24248-8openalex-snapshot
Use of statins and the risk of dementia and mild cognitive impairment: A systematic review and meta-analysis
inferredcites →https://doi.org/10.1073/pnas.0813138106openalex-snapshot
A scissors mechanism for stimulation of SNARE-mediated lipid mixing by cholesterol
inferredcites →https://doi.org/10.1073/pnas.081620098openalex-snapshot
Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo
inferredcites →https://doi.org/10.1073/pnas.1609896113openalex-snapshot
Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes
inferredcites →https://doi.org/10.1073/pnas.1620506114openalex-snapshot
Loss of astrocyte cholesterol synthesis disrupts neuronal function and alters whole-body metabolism
inferredcites →https://doi.org/10.1073/pnas.1821306116openalex-snapshot
Gene expression in oligodendrocytes during remyelination reveals cholesterol homeostasis as a therapeutic target in multiple sclerosis
inferredcites →https://doi.org/10.1073/pnas.90.5.1977openalex-snapshot
Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.
inferredcites →https://doi.org/10.1073/pnas.95.11.6460openalex-snapshot
Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons
inferredcites →https://doi.org/10.1073/pnas.96.20.11049openalex-snapshot
Cellular mechanisms of β-amyloid production and secretion
inferredcites →https://doi.org/10.1074/jbc.m111.225532openalex-snapshot
Apolipoprotein E Regulates the Integrity of Tight Junctions in an Isoform-dependent Manner in an in Vitro Blood-Brain Barrier Model
inferredcites →https://doi.org/10.1074/jbc.m111.295451openalex-snapshot
Apolipoprotein E Promotes β-Amyloid Trafficking and Degradation by Modulating Microglial Cholesterol Levels
inferredcites →https://doi.org/10.1074/jbc.m114.625251openalex-snapshot
Apolipoprotein E Inhibits Cerebrovascular Pericyte Mobility through a RhoA Protein-mediated Pathway
inferredcites →https://doi.org/10.1074/jbc.m115.664367openalex-snapshot
Effect of Cholesterol Reduction on Receptor Signaling in Neurons
inferredcites →https://doi.org/10.1074/jbc.m504484200openalex-snapshot
Lipids as Modulators of Proteolytic Activity of BACE
inferredcites →https://doi.org/10.1080/14647270802336650openalex-snapshot
Influence of Hypercholesterolemia and Hypertension on the Integrity of the Blood–Brain Barrier in Rats
inferredcites →https://doi.org/10.1084/jem.20171265openalex-snapshot
ApoE facilitates the microglial response to amyloid plaque pathology
inferredcites →https://doi.org/10.1093/brain/awv166openalex-snapshot
CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer’s disease
inferredcites →https://doi.org/10.1096/fj.10-168633openalex-snapshot
Local cholesterol increase triggers amyloid precursor protein‐Bacel clustering in lipid rafts and rapid endocytosis
inferredcites →https://doi.org/10.1101/cshperspect.a006312openalex-snapshot
Apolipoprotein E and Apolipoprotein E Receptors: Normal Biology and Roles in Alzheimer Disease
inferredcites →https://doi.org/10.1111/acel.12932openalex-snapshot
Age‐associated cholesterol reduction triggers brain insulin resistance by facilitating ligand‐independent receptor activation and pathway desensitization
inferredcites →https://doi.org/10.1111/j.1471-4159.2009.05917.xopenalex-snapshot
Marked differences in cholesterol synthesis between neurons and glial cells from postnatal rats
inferredcites →https://doi.org/10.1111/jnc.12637openalex-snapshot
Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis
inferredcites →https://doi.org/10.1126/science.295.5563.2213aopenalex-snapshot
Cholesterol's Role in Synapse Formation
inferredcites →https://doi.org/10.1126/science.8346443openalex-snapshot
Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families
inferredcites →https://doi.org/10.1126/science.aan4183openalex-snapshot
Defective cholesterol clearance limits remyelination in the aged central nervous system
inferredcites →https://doi.org/10.1146/annurev-neuro-061010-113613openalex-snapshot
Amyloid Precursor Protein Processing and Alzheimer's Disease
inferredcites →https://doi.org/10.1155/2012/109324openalex-snapshot
Simvastatin Blocks Blood-Brain Barrier Disruptions Induced by Elevated Cholesterol Both In Vivo and In Vitro
inferredcites →https://doi.org/10.1161/01.atv.0000103951.67680.b1openalex-snapshot
Decoding Transcriptional Programs Regulated by PPARs and LXRs in the Macrophage
inferredcites →https://doi.org/10.1172/jci6179openalex-snapshot
Expression of human apolipoprotein E reduces amyloid-β deposition in a mouse model of Alzheimer's disease
inferredcites →https://doi.org/10.1172/jci90604openalex-snapshot
Transcriptional control of microglia phenotypes in health and disease
inferredcites →https://doi.org/10.1186/1750-1326-9-60openalex-snapshot
Increasing membrane cholesterol of neurons in culture recapitulates Alzheimer’s disease early phenotypes
inferredcites →https://doi.org/10.1186/s13024-018-0262-8openalex-snapshot
The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer’s disease
inferredcites →https://doi.org/10.1186/s13041-014-0085-7openalex-snapshot
Statin treatment affects cytokine release and phagocytic activity in primary cultured microglia through two separable mechanisms
inferredcites →https://doi.org/10.1194/jlr.r009761openalex-snapshot
Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models
inferredcites →https://doi.org/10.1212/01.wnl.0000070182.02537.84openalex-snapshot
Mild hypercholesterolemia is an early risk factor for the development of Alzheimer amyloid pathology
inferredcites →https://doi.org/10.1212/01.wnl.0000333215.93440.36openalex-snapshot
Brain cholesterol metabolism and neurologic disease
inferredcites →https://doi.org/10.1242/dmm.010124openalex-snapshot
Dysregulation of cholesterol balance in the brain: contribution to neurodegenerative diseases
inferredcites →https://doi.org/10.1242/jcs.060681openalex-snapshot
Cholesterol reduction impairs exocytosis of synaptic vesicles
inferredcites →https://doi.org/10.1371/journal.pbio.1002605openalex-snapshot
Oligodendroglial myelination requires astrocyte-derived lipids
inferredcites →https://doi.org/10.14348/molcells.2014.0248openalex-snapshot
Apolipoprotein E in Synaptic Plasticity and Alzheimer’s Disease: Potential Cellular and Molecular Mechanisms
inferredcites →https://doi.org/10.1523/jneurosci.1860-14.2014openalex-snapshot
An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
inferredcites →https://doi.org/10.1523/jneurosci.2262-17.2018openalex-snapshot
Human ApoE Isoforms Differentially Modulate Brain Glucose and Ketone Body Metabolism: Implications for Alzheimer's Disease Risk Reduction and Early Intervention
inferredcites →https://doi.org/10.1523/jneurosci.3773-11.2011openalex-snapshot
Haploinsufficiency of Human APOE Reduces Amyloid Deposition in a Mouse Model of Amyloid-β Amyloidosis
inferredcites →https://doi.org/10.1523/jneurosci.4586-14.2015openalex-snapshot
Nuclear Receptors License Phagocytosis by Trem2+Myeloid Cells in Mouse Models of Alzheimer's Disease
inferredcites →https://doi.org/10.1523/jneurosci.5476-05.2006openalex-snapshot
Profile and Regulation of Apolipoprotein E (ApoE) Expression in the CNS in Mice with Targeting of Green Fluorescent Protein Gene to the ApoE Locus
inferredcites →https://doi.org/10.15252/emmm.201606210openalex-snapshot
The amyloid hypothesis of Alzheimer's disease at 25 years
inferredcites →https://doi.org/10.2174/138161206780574579openalex-snapshot
PPAR-γ Agonists as Regulators of Microglial Activation and Brain Inflammation
inferredcites →https://doi.org/10.3389/fcell.2016.00071openalex-snapshot
Oligodendrocyte, Astrocyte, and Microglia Crosstalk in Myelin Development, Damage, and Repair
inferredcites →https://doi.org/10.3892/ijmm.2013.1233openalex-snapshot
Hypercholesterolemia accelerates amyloid β-induced cognitive deficits
inferredcites →https://doi.org/10.3892/ijmm.2018.3456openalex-snapshot
Mitochondrial protective mechanism of simvastatin protects against amyloid�β peptide-induced injury in SH-SY5Y cells
inferredcites →https://doi.org/10.4061/2011/810981openalex-snapshot
Introducing Human APOE into Aβ Transgenic Mouse Models
inferredcites →https://doi.org/10.7892/boris.125653openalex-snapshot
Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Prioritizing Modifiable Risk Factors for Dementia Prevention across the Spectrum of Genetic Susceptibility: A Prospective Cohort Study
inferred← citeshttps://doi.org/10.1002/jcp.30999openalex-snapshot
Human neurons lacking amyloid precursor protein exhibit cholesterol‐associated developmental and presynaptic deficits
inferred← citeshttps://doi.org/10.1007/978-1-0716-2573-6_13openalex-snapshot
Pharmacogenomics of Alzheimer’s Disease: Novel Strategies for Drug Utilization and Development
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Unveiling the Nexus Between the APOE Gene and Anxiety/Depression: A Comprehensive Review
inferred← citeshttps://doi.org/10.1007/978-3-031-43883-7_17openalex-snapshot
The Diagnostic Use of the Plasma Quantification of 24S-Hydroxycholesterol and Other Oxysterols in Neurodegenerative Disease
inferred← citeshttps://doi.org/10.1007/978-3-031-73368-0_9openalex-snapshot
Unveiling the Nexus Between the APOE Gene and Anxiety/Depression: A Comprehensive Review
inferred← citeshttps://doi.org/10.1007/s00429-020-02155-xopenalex-snapshot
AAV delivery of shRNA against IRS1 in GABAergic neurons in rat hippocampus impairs spatial memory in females and male rats
inferred← citeshttps://doi.org/10.1007/s00604-024-06365-6openalex-snapshot
DNA tetrahedron-based dual-signal fluorescence detection of apoE4 gene sites on a microplate reader
inferred← citeshttps://doi.org/10.1007/s10571-023-01365-1openalex-snapshot
Roles of ApoE4 on the Pathogenesis in Alzheimer’s Disease and the Potential Therapeutic Approaches
inferred← citeshttps://doi.org/10.1007/s11011-020-00622-2openalex-snapshot
Insulin resistance: a connecting link between Alzheimer’s disease and metabolic disorder
inferred← citeshttps://doi.org/10.1007/s11357-021-00458-3openalex-snapshot
Mediation of the APOE associations with Alzheimer’s and coronary heart diseases through body mass index and lipids
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Nutrition in Alzheimer’s disease: a review of an underappreciated pathophysiological mechanism
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Impact of Genetic Risk Factors for Alzheimer’s Disease on Brain Glucose Metabolism
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The Relationship of Omega-3 Fatty Acids with Dementia and Cognitive Decline: Evidence from Prospective Cohort Studies of Supplementation, Dietary Intake, and Blood Markers
inferred← citeshttps://doi.org/10.1016/j.apsb.2025.06.018openalex-snapshot
A mechanism underlying the association of Aβ plaque and lipid droplets in Alzheimer's disease
inferred← citeshttps://doi.org/10.1016/j.biochi.2022.08.012openalex-snapshot
Fatty acid sensing in the brain: The role of glial-neuronal metabolic crosstalk and horizontal lipid flux
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.116071openalex-snapshot
The function of sphingolipids in different pathogenesis of Alzheimer's disease: A comprehensive review
inferred← citeshttps://doi.org/10.1016/j.csda.2025.108280openalex-snapshot
Fast autoregressive model for multivariate dependent outcomes with application to lipidomics analysis for Alzheimer’s disease and APOE- ε 4
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e30523openalex-snapshot
RETRACTED: The Intersection of cerebral cholesterol metabolism and Alzheimer's disease: Mechanisms and therapeutic prospects
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Potential of astrocytes in targeting therapy for Alzheimer’s disease
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Behavioral, metabolic, and lipidomic characterization of the 5xFADxTg30 mouse model of Alzheimer’s disease
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Cholesterol-metabolism, plant sterols, and long-term cognitive decline in older people – Effects of sex and APOEe4
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Oxysterol-binding protein ORP6 regulates lipid metabolism and brain Aβ production
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Cholesterol dysregulation in peripheral blood mononuclear cells of Alzheimer's disease
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Decline in biological resilience as key manifestation of aging: Potential mechanisms and role in health and longevity
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Could COVID-19 anosmia and olfactory dysfunction trigger an increased risk of future dementia in patients with ApoE4?
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Prevention of Alzheimer's disease through diet: An exploratory review
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Contrasting association pattern of plasma low-density lipoprotein with white matter integrity in APOE4 carriers versus non-carriers
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The genetic risk factors, molecular pathways, microRNAs, and the gut microbiome in Alzheimer’s disease
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GPR101 loss promotes insulin resistance and diet-induced obesity risk
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Brain cell type-specific cholesterol metabolism and implications for learning and memory
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Assessing the causal role of lipid metabolites in Alzheimer's disease: A mendelian randomization study
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Effect of obicetrapib, a potent cholesteryl ester transfer protein inhibitor, on p-tau217 levels in patients with cardiovascular disease
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A possible role of Apolipoprotein E in Idiopathic Generalized Epilepsy
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AAVrh.10 delivery of novel APOE2-Christchurch variant suppresses amyloid and Tau pathology in Alzheimer’s disease mice
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In Vivo Metabolic Labeling with an Isoprenoid Probe Reveals APOE Allele-Specific Differences in the Prenylome
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Mercury Ion Binding to Apolipoprotein E Variants ApoE2, ApoE3, and ApoE4: Similar Binding Affinities but Different Structure Induction Effects
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Plasma lipidome is dysregulated in Alzheimer’s disease and is associated with disease risk genes
inferred← citeshttps://doi.org/10.1038/s41398-022-01881-6openalex-snapshot
Effects of APOE4 allelic dosage on lipidomic signatures in the entorhinal cortex of aged mice
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Identification of Chlamydia pneumoniae and NLRP3 inflammasome activation in Alzheimer’s disease retina
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Astrocyte contribution to dysfunction, risk and progression in neurodegenerative disorders
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An evidence-based review of neuronal cholesterol role in dementia and statins as a pharmacotherapy in reducing risk of dementia
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Short-term exposure to polystyrene microplastics alters cognition, immune, and metabolic markers in an apolipoprotein E (APOE) genotype and sex-dependent manner
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Suppression of CNS APOE4 Expression by miRNAs Delivered by the S2 AAVrh.10 Capsid-Modified AAV Vector
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Diabetes and hypertension are related to amyloid-beta burden in the population-based Rotterdam Study
inferred← citeshttps://doi.org/10.1093/brain/awae018openalex-snapshot
Elevated cholesterol in ATAD3 mutants is a compensatory mechanism that leads to membrane cholesterol aggregation
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Cholesterol Dysregulation in APOE4 Astrocytes Promotes α-Synuclein Pathology in miBrains, a Human Brain Tissue Model
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Short-Term Exposure to Polystyrene Microplastics Alters Cognition, Immune, and Metabolic Markers in an APOE Genotype and Sex-Dependent Manner
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Impaired cellular copper regulation in the presence of ApoE4
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Sex and APOE Genotype Alter the Basal and Induced Inflammatory States of Primary Astrocytes from Humanized Targeted Replacement Mice
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Exploration of acupuncture therapy in the treatment of MCI patients with the ApoE ε4 gene based on the brain-gut axis theory
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A novel apoE-mimetic increases brain apoE levels, reduces Aβ pathology and improves memory when treated before onset of pathology in male mice that express APOE3
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Statin Initiation and Risk of Incident Alzheimer Disease and Cognitive Decline in Genetically Susceptible Older Adults
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Analysis of Comorbidities between Depression and Alzheimer’s Disease and Intervention Methods
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Modulatory Effect of Blood LDL Cholesterol on the Association between Cerebral Aβ and Tau Deposition in Older Adults
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Benefits of using the CRISPR-Cas9 system in the modification of genetic disorders
inferred← citeshttps://doi.org/10.20900/immunometab20210003openalex-snapshot
Pathogens Hijack Host Cell Metabolism: Intracellular Infection as a Driver of the Warburg Effect in Cancer and Other Chronic Inflammatory Conditions
inferred← citeshttps://doi.org/10.21203/rs.3.rs-580913/v1openalex-snapshot
APOEe4.Trem2*R47H Mice Show Changes in Alzheimer’s Disease-Relevant Processes in the Absence of Amyloid Plaques
inferred← citeshttps://doi.org/10.2147/nds.s496926openalex-snapshot
Dietary Saturated Fat Intake Moderates the Effect of Plasma Triglycerides on Memory Performance in Middle-Aged Adults
inferred← citeshttps://doi.org/10.23860/iannucci-jaclyn-2020openalex-snapshot
INVESTIGATING THE ROLE OF VASCULAR ACTIVATION IN ALZHEIMER’S DISEASE-RELATED NEUROINFLAMMATION
inferred← citeshttps://doi.org/10.29245/2572.942x/2020/2.1265openalex-snapshot
RIP140 in Stress Response of the Brain
inferred← citeshttps://doi.org/10.3103/s0891416823030084openalex-snapshot
Benefits of Using the CRISPR/Cas9 System for the Correction of Genetic Mutations
inferred← citeshttps://doi.org/10.3233/jad-200206openalex-snapshot
A Coordinated Approach by Public Domain Bioinformatics Resources to Aid the Fight Against Alzheimer’s Disease Through Expert Curation of Key Protein Targets
inferred← citeshttps://doi.org/10.3233/jad-220374openalex-snapshot
Cognitive Improvement After Multi-Domain Lifestyle Interventions in an APOE ɛ4 Homozygous Carrier with Mild Cognitive Impairment: A Case Report and Literature Review
inferred← citeshttps://doi.org/10.3233/jad-230516openalex-snapshot
PICALM Variation Moderates the Relationships of APOE ɛ4 with Alzheimer’s Disease Cerebrospinal Biomarkers and Memory Function Among Non-Demented Population
inferred← citeshttps://doi.org/10.3233/jad-231432openalex-snapshot
Alzheimer’s Disease in Lebanon: Exploring Genetic and Environmental Risk Factors—A Comprehensive Review
inferred← citeshttps://doi.org/10.3389/fgene.2023.1203017openalex-snapshot
Molecular genetics of neuropsychiatric illness: some musings
inferred← citeshttps://doi.org/10.3389/fgene.2023.1236509openalex-snapshot
Interactions between genes involved in physiological dysregulation and axon guidance: role in Alzheimer’s disease
inferred← citeshttps://doi.org/10.3389/fnagi.2020.00005openalex-snapshot
Low-Density Lipoprotein Cholesterol and Alzheimer's Disease: A Systematic Review and Meta-Analysis
inferred← citeshttps://doi.org/10.3389/fnagi.2021.690372openalex-snapshot
Cholesterol and Alzheimer’s Disease; From Risk Genes to Pathological Effects
inferred← citeshttps://doi.org/10.3389/fnagi.2021.735524openalex-snapshot
Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H
inferred← citeshttps://doi.org/10.3389/fnagi.2021.766587openalex-snapshot
Neurodegenerative Diseases and Cholesterol: Seeing the Field Through the Players
inferred← citeshttps://doi.org/10.3389/fnagi.2023.1087072openalex-snapshot
APOE ε4 allele, along with G206D-PSEN1 mutation, alters mitochondrial networks and their degradation in Alzheimer’s disease
inferred← citeshttps://doi.org/10.3389/fnagi.2023.1096206openalex-snapshot
White matter injury, cholesterol dysmetabolism, and APP/Abeta dysmetabolism interact to produce Alzheimer’s disease (AD) neuropathology: A hypothesis and review
inferred← citeshttps://doi.org/10.3389/fnagi.2025.1587986openalex-snapshot
Insights into targeted ferroptosis in mechanisms, biology, and role of Alzheimer's disease: an update
inferred← citeshttps://doi.org/10.3389/fnsyn.2026.1845252openalex-snapshot
Zebrafish as a translational model for peptide-mediated synaptic dysfunction related to obesity
inferred← citeshttps://doi.org/10.3390/antiox10040572openalex-snapshot
Acetyl-CoA Metabolism and Histone Acetylation in the Regulation of Aging and Lifespan
inferred← citeshttps://doi.org/10.3390/antiox10121890openalex-snapshot
Cholesterol Dysmetabolism in Alzheimer’s Disease: A Starring Role for Astrocytes?
inferred← citeshttps://doi.org/10.3390/antiox11112168openalex-snapshot
ApoE3 vs. ApoE4 Astrocytes: A Detailed Analysis Provides New Insights into Differences in Cholesterol Homeostasis
inferred← citeshttps://doi.org/10.3390/biom11091361openalex-snapshot
Beyond the GFAP-Astrocyte Protein Markers in the Brain
inferred← citeshttps://doi.org/10.3390/biomedicines10112922openalex-snapshot
Interdisciplinary Approaches to Deal with Alzheimer’s Disease—From Bench to Bedside: What Feasible Options Do Already Exist Today?
inferred← citeshttps://doi.org/10.3390/brainsci12101290openalex-snapshot
Statins Use in Alzheimer Disease: Bane or Boon from Frantic Search and Narrative Review
inferred← citeshttps://doi.org/10.3390/brainsci12101405openalex-snapshot
Alzheimer’s Disease and SARS-CoV-2: Pathophysiological Analysis and Social Context
inferred← citeshttps://doi.org/10.3390/cells12030420openalex-snapshot
The Breakthroughs and Caveats of Using Human Pluripotent Stem Cells in Modeling Alzheimer’s Disease
inferred← citeshttps://doi.org/10.3390/cells9102173openalex-snapshot
Astrocytic Factors Controlling Synaptogenesis: A Team Play
inferred← citeshttps://doi.org/10.3390/cimb43010018openalex-snapshot
Isoform-Specific Effects of Apolipoprotein E on Markers of Inflammation and Toxicity in Brain Glia and Neuronal Cells In Vitro
inferred← citeshttps://doi.org/10.3390/ijms21134812openalex-snapshot
Steroids and Alzheimer’s Disease: Changes Associated with Pathology and Therapeutic Potential
inferred← citeshttps://doi.org/10.3390/ijms21176336openalex-snapshot
ApoE Lipidation as a Therapeutic Target in Alzheimer’s Disease
inferred← citeshttps://doi.org/10.3390/ijms23169356openalex-snapshot
HDL-like-Mediated Cell Cholesterol Trafficking in the Central Nervous System and Alzheimer’s Disease Pathogenesis
inferred← citeshttps://doi.org/10.3390/ijms23179829openalex-snapshot
Sex and APOE Genotype Alter the Basal and Induced Inflammatory States of Primary Microglia from APOE Targeted Replacement Mice
inferred← citeshttps://doi.org/10.3390/ijms232113630openalex-snapshot
Astrocytes as a Therapeutic Target in Alzheimer’s Disease–Comprehensive Review and Recent Developments
inferred← citeshttps://doi.org/10.3390/ijms24108904openalex-snapshot
Potential Role of Protein Kinase FAM20C on the Brain in Raine Syndrome, an In Silico Analysis
inferred← citeshttps://doi.org/10.3390/ijms241713395openalex-snapshot
Alteration of Blood Immune Biomarkers in MCI Patients with Different APOE Genotypes after Cognitive Training: A 1 Year Follow-Up Cohort Study
inferred← citeshttps://doi.org/10.3390/jcm13071948openalex-snapshot
Normal-Tension Glaucoma and Potential Clinical Links to Alzheimer’s Disease
inferred← citeshttps://doi.org/10.3390/life12030460openalex-snapshot
Personalized Management and Treatment of Alzheimer’s Disease
inferred← citeshttps://doi.org/10.3390/nu13093040openalex-snapshot
High-Fat and Resveratrol Supplemented Diets Modulate Adenosine Receptors in the Cerebral Cortex of C57BL/6J and SAMP8 Mice
inferred← citeshttps://doi.org/10.3390/pathogens11080933openalex-snapshot
Memory Impairment, Pro-Inflammatory Host Response and Brain Histopathologic Severity in Rats Infected with K. pneumoniae or P. aeruginosa Meningitis
inferred← citeshttps://doi.org/10.4103/nrr.nrr-d-23-01462openalex-snapshot
Cholesterol metabolism: physiological versus pathological aspects in intracerebral hemorrhage
inferred← citeshttps://doi.org/10.4103/nrr.nrr-d-23-01470openalex-snapshot
Isoform- and cell-state-specific APOE homeostasis and function
inferred← citeshttps://doi.org/10.6035/14112.2021.368012openalex-snapshot
Neuroinflammation and insulin resistance underly cognitive impairment. Sex differences and potential treatments
inferred← citeshttps://doi.org/10.64898/2025.12.16.694774openalex-snapshot
High-density lipoprotein mimetic peptide 4F ameliorates APOE4-associated lipid dysfunction in primary and iPSC-derived astrocytes and cerebral organoids
inferred← citeshttps://doi.org/10.7717/peerj.16740openalex-snapshot
Regulation of lipid metabolism by APOE4 in intrahepatic cholangiocarcinoma via the enhancement of ABCA1 membrane expression
inferred← citeshttps://doi.org/10.7759/cureus.12008openalex-snapshot
Plasma Lipids as Biomarkers for Alzheimer's Disease: A Systematic Review
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