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Dysregulation of Local Stem/Progenitor Cells as a Common Cellular Mechanism for Heterotopic Ossification

https://doi.org/10.1634/stemcells.2008-0576
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ajmg.a.32151openalex-snapshot
A unique case of fibrodysplasia ossificans progressiva with an ACVR1 mutation, G356D, other than the common mutation (R206H)
inferredcites →https://doi.org/10.1002/dvg.20226openalex-snapshot
Nestin‐Cre transgenic mouse line Nes‐Cre1 mediates highly efficient Cre/loxP mediated recombination in the nervous system, kidney, and somite‐derived tissues
inferredcites →https://doi.org/10.1002/jbm.a.10275openalex-snapshot
Titanium surface topography alters cell shape and modulates bone morphogenetic protein 2 expression in the J774A.1 macrophage cell line
inferredcites →https://doi.org/10.1002/path.1413openalex-snapshot
Stromal cells of fibrodysplasia ossificans progressiva lesions express smooth muscle lineage markers and the osteogenic transcription factor Runx2/Cbfa‐1: clues to a vascular origin of heterotopic ossification?
inferredcites →https://doi.org/10.1007/978-3-319-92193-8_18openalex-snapshot
Heterotopic Ossification
inferredcites →https://doi.org/10.1007/s00256-005-0958-zopenalex-snapshot
Heterotopic ossification: a review
inferredcites →https://doi.org/10.1007/s004010051041openalex-snapshot
Local expression of monocyte chemoattractant protein-1 (MCP-1) in idiopathic inflammatory myopathies
inferredcites →https://doi.org/10.1007/s004020000178openalex-snapshot
Effects of single-dose versus fractionated irradiation on the suppression of heterotopic bone formation - an animal model-based follow-up study in rats
inferredcites →https://doi.org/10.1007/springerreference_38489openalex-snapshot
Heterotopic ossification
inferredcites →https://doi.org/10.1016/0022-1759(89)90178-6openalex-snapshot
The liposome-mediated macrophage ‘suicide’ technique
inferredcites →https://doi.org/10.1016/0092-8674(92)90030-gopenalex-snapshot
RAG-1-deficient mice have no mature B and T lymphocytes
inferredcites →https://doi.org/10.1016/j.bbrc.2006.05.013openalex-snapshot
Elevated extracellular calcium stimulates secretion of bone morphogenetic protein 2 by a macrophage cell line
inferredcites →https://doi.org/10.1016/j.bbrc.2006.08.089openalex-snapshot
Adenovirus-mediated transfer of siRNA against Runx2/Cbfa1 inhibits the formation of heterotopic ossification in animal model
inferredcites →https://doi.org/10.1016/j.ijrobp.2006.03.053openalex-snapshot
Heterotopic ossification: Pathophysiology, clinical features, and the role of radiotherapy for prophylaxis
inferredcites →https://doi.org/10.1016/j.orthres.2004.05.003openalex-snapshot
The origin of osteoprogenitor cells responsible for heterotopic ossification following hip surgery: An animal model in the rabbit
inferredcites →https://doi.org/10.1016/j.stem.2008.03.002openalex-snapshot
Mesenchymal Stem Cells: Revisiting History, Concepts, and Assays
inferredcites →https://doi.org/10.1016/j.ydbio.2007.07.026openalex-snapshot
Dual function of Sox1 in telencephalic progenitor cells
inferredcites →https://doi.org/10.1016/s0002-9440(10)63372-xopenalex-snapshot
Transgenic Mice Overexpressing BMP4 Develop a Fibrodysplasia Ossificans Progressiva (FOP)-Like Phenotype
inferredcites →https://doi.org/10.1016/s0006-8993(00)03135-8openalex-snapshot
Depletion of systemic macrophages by liposome-encapsulated clodronate attenuates striatal macrophage invasion and neurodegeneration following local endotoxin infusion in gerbils
inferredcites →https://doi.org/10.1016/s8756-3282(01)00638-xopenalex-snapshot
Macrophage cell lines produce osteoinductive signals that include bone morphogenetic protein-2
inferredcites →https://doi.org/10.1023/a:1008942828960openalex-snapshot
Conditional gene targeting in macrophages and granulocytes using LysMcre mice
inferredcites →https://doi.org/10.1034/j.1399-3089.2000.00071.xopenalex-snapshot
Pig islet xenograft rejection is markedly delayed in macrophage‐depleted mice: a study in streptozotocin diabetic animals
inferredcites →https://doi.org/10.1038/ng1783openalex-snapshot
A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva
inferredcites →https://doi.org/10.1038/sj.bjc.6603240openalex-snapshot
Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach
inferredcites →https://doi.org/10.1053/hupa.2001.26464openalex-snapshot
Mast cell involvement in fibrodysplasia ossificans progressiva
inferredcites →https://doi.org/10.1073/pnas.92.26.12070openalex-snapshot
T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination.
inferredcites →https://doi.org/10.1080/16501970510027628openalex-snapshot
Heterotopic ossification: A review
inferredcites →https://doi.org/10.1093/jnen/60.7.676openalex-snapshot
Bone Marrow Chimeric Rats Reveal the Unique Distribution of Resident and Recruited Macrophages in the Contused Rat Spinal Cord
inferredcites →https://doi.org/10.1093/nar/25.6.1317openalex-snapshot
B lymphocyte-specific, Cre-mediated mutagenesis in mice
inferredcites →https://doi.org/10.1097/00003086-199202000-00042openalex-snapshot
Pericytes as a Supplementary Source of Osteoblasts in Periosteal Osteogenesis
inferredcites →https://doi.org/10.1097/00003086-199801000-00012openalex-snapshot
Animal Models of Heterotopic Ossification
inferredcites →https://doi.org/10.1097/00007890-197108000-00001openalex-snapshot
OSTEOGENIC PRECURSOR CELLS OF BONE MARROW IN RADIATION CHIMERAS
inferredcites →https://doi.org/10.1097/01.blo.0000129557.38803.26openalex-snapshot
Influenza-like Viral Illnesses and Flare-ups of Fibrodysplasia Ossificans Progressiva
inferredcites →https://doi.org/10.1126/stke.3992007cm1openalex-snapshot
TGF-β Signaling in Development
inferredcites →https://doi.org/10.1159/000129159openalex-snapshot
Tissue Reaction to Polypropylene Mesh: A Study of Oedema, Blood Flow, and Inflammation in the Abdominal Wall
inferredcites →https://doi.org/10.1161/01.res.0000260802.75766.00openalex-snapshot
Monocyte/Macrophage Suppression in CD11b Diphtheria Toxin Receptor Transgenic Mice Differentially Affects Atherogenesis and Established Plaques
inferredcites →https://doi.org/10.1172/jci200522675openalex-snapshot
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
inferredcites →https://doi.org/10.1182/blood.v96.8.2834openalex-snapshot
Treatment with liposome-encapsulated clodronate as a new strategic approach in the management of immune thrombocytopenic purpura in a mouse model
inferredcites →https://doi.org/10.1242/dev.127.23.5059openalex-snapshot
Early myotome specification regulates PDGFA expression and axial skeleton development
inferredcites →https://doi.org/10.2106/00004623-198062050-00017openalex-snapshot
Myositis ossificans following forcible manipulation of the leg. A rabbit model for the study of heterotopic bone formation.
inferredcites →https://doi.org/10.3727/096020198389898openalex-snapshot
Changes in Mass and Performance in Rabbit Muscles after Muscle Damage with or without Transplantation of Primary Satellite Cells
inferredcites →https://doi.org/10.5435/00124635-200403000-00007openalex-snapshot
Heterotopic Ossification

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.3986891openalex-extracted
Sustained Local Ionic Homeostatic Imbalance (SLIHI) Caused by Calcification Modulates Inflammation to Trigger Ectopic Bone Formation
inferred← citeshttps://doi.org/10.1002/9781118453926.ch14openalex-snapshot
Circulating Osteogenic Cells
inferred← citeshttps://doi.org/10.1002/adbi.201700156openalex-snapshot
An In Vitro Model for the Development of Mature Bone Containing an Osteocyte Network
inferred← citeshttps://doi.org/10.1002/advs.202310282openalex-snapshot
Spatiotemporal Analysis of Mesenchymal Stem Cells Fate Determination by Inflammatory Niche Following Soft Tissue Injury at a Single‐Cell Level
inferred← citeshttps://doi.org/10.1002/ame2.12439openalex-snapshot
Animal models of tendon calcification: Past, present, and future
inferred← citeshttps://doi.org/10.1002/cyto.b.21594openalex-snapshot
Peripheral Blood Mononuclear Cell Immunophenotyping in Fibrodysplasia Ossificans Progressiva Patients: Evidence for Monocyte DNAM1 Up‐regulation
inferred← citeshttps://doi.org/10.1002/dvdy.24openalex-snapshot
Limb specific Acvr1‐knockout during embryogenesis in mice exhibits great toe malformation as seen in Fibrodysplasia Ossificans Progressiva (FOP)
inferred← citeshttps://doi.org/10.1002/dvdy.24606openalex-snapshot
Animal models of fibrodysplasia ossificans progressiva
inferred← citeshttps://doi.org/10.1002/jbm4.10172openalex-snapshot
Heterotopic Ossification: A Comprehensive Review
inferred← citeshttps://doi.org/10.1002/jbmr.1562openalex-snapshot
Multipotent progenitors resident in the skeletal muscle interstitium exhibit robust BMP-dependent osteogenic activity and mediate heterotopic ossification
inferred← citeshttps://doi.org/10.1002/jbmr.1921openalex-snapshot
Plasminogen Plays a Crucial Role in Bone Repair
inferred← citeshttps://doi.org/10.1002/jbmr.2735openalex-snapshot
Macrophages: Their Emerging Roles in Bone
inferred← citeshttps://doi.org/10.1002/jbmr.3304openalex-snapshot
Depletion of Mast Cells and Macrophages Impairs Heterotopic Ossification in an Acvr1R206H Mouse Model of Fibrodysplasia Ossificans Progressiva
inferred← citeshttps://doi.org/10.1002/jbmr.3349openalex-snapshot
Reply to: Macrophages Driving Heterotopic Ossification: Convergence of Genetically-Driven and Trauma-Driven Mechanisms
inferred← citeshttps://doi.org/10.1002/jbmr.370openalex-snapshot
Circulating osteogenic cells: Implications for injury, repair, and regeneration
inferred← citeshttps://doi.org/10.1002/jcb.23259openalex-snapshot
Substance P signaling mediates BMP-dependent heterotopic ossification
inferred← citeshttps://doi.org/10.1002/jor.23833openalex-snapshot
Crosstalk between substance P and calcitonin gene‐related peptide during heterotopic ossification in murine Achilles tendon
inferred← citeshttps://doi.org/10.1002/stem.150openalex-snapshot
Circulating Osteogenic Precursor Cells in Heterotopic Bone Formation
inferred← citeshttps://doi.org/10.1007/978-1-84882-822-3_14openalex-snapshot
Fibrodysplasia Ossificans Progressiva: Developmental Implications of a Novel Metamorphogene
inferred← citeshttps://doi.org/10.1007/978-3-030-32256-4_265-1openalex-snapshot
Myositis Ossificans
inferred← citeshttps://doi.org/10.1007/978-3-030-46725-8_14openalex-snapshot
Heterotopic Ossification Following Traumatic Blast Injury
inferred← citeshttps://doi.org/10.1007/978-3-031-26449-8_265openalex-snapshot
Myositis Ossificans
inferred← citeshttps://doi.org/10.1007/978-3-319-47507-3_14openalex-snapshot
BMP Signaling in Fibrodysplasia Ossificans Progressiva, a Rare Genetic Disorder of Heterotopic Ossification
inferred← citeshttps://doi.org/10.1007/s00402-015-2174-1openalex-snapshot
Pathogenesis and prevention strategies of heterotopic ossification in total hip arthroplasty: a narrative literature review and results of a survey in Germany
inferred← citeshttps://doi.org/10.1007/s11914-015-0258-zopenalex-snapshot
The Immunological Contribution to Heterotopic Ossification Disorders
inferred← citeshttps://doi.org/10.1007/s11914-019-00541-xopenalex-snapshot
Inflammation in Fibrodysplasia Ossificans Progressiva and Other Forms of Heterotopic Ossification
inferred← citeshttps://doi.org/10.1007/s11914-021-00673-zopenalex-snapshot
Do Interactions of Vitamin D3 and BMP Signaling Hold Implications in the Pathogenesis of Fibrodysplasia Ossificans Progressiva?
inferred← citeshttps://doi.org/10.1016/b978-0-12-381298-8.00018-6openalex-snapshot
Investigations of Activated ACVR1/ALK2, a Bone Morphogenetic Protein Type I Receptor, That Causes Fibrodysplasia Ossificans Progressiva
inferred← citeshttps://doi.org/10.1016/b978-0-12-382040-2.10030-9openalex-snapshot
Extraskeletal Bone Formation
inferred← citeshttps://doi.org/10.1016/b978-0-12-801238-3.66152-4openalex-snapshot
Heterotopic Ossification and Calcification
inferred← citeshttps://doi.org/10.1016/b978-0-12-804182-6.00030-7openalex-snapshot
Fibrodysplasia (Myositis) Ossificans Progressiva
inferred← citeshttps://doi.org/10.1016/b978-0-12-813503-7.00001-7openalex-snapshot
Material characteristics, surface/interface, and biological effects on the osteogenesis of bioactive materials
inferred← citeshttps://doi.org/10.1016/b978-0-12-814841-9.00081-6openalex-snapshot
Methods in lineage tracing
inferred← citeshttps://doi.org/10.1016/b978-0-323-34169-1.00057-7openalex-snapshot
Heterotopic Ossification
inferred← citeshttps://doi.org/10.1016/j.actbio.2022.03.057openalex-snapshot
Sustained local ionic homeostatic imbalance caused by calcification modulates inflammation to trigger heterotopic ossification
inferred← citeshttps://doi.org/10.1016/j.ajpath.2018.07.014openalex-snapshot
Characterizing the Circulating Cell Populations in Traumatic Heterotopic Ossification
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2014.03.013openalex-snapshot
Liposomal clodronate inhibition of osteoclastogenesis and osteoinduction by submicrostructured beta-tricalcium phosphate
inferred← citeshttps://doi.org/10.1016/j.bjoms.2014.04.012openalex-snapshot
Piezoelectric osteoarthrectomy for management of ankylosis of the temporomandibular joint
inferred← citeshttps://doi.org/10.1016/j.bjps.2016.11.026openalex-snapshot
Pressure ulcer reconstruction in patients with heterotopic ossification after spinal cord injury: A case series and review of literature
inferred← citeshttps://doi.org/10.1016/j.bone.2012.09.018openalex-snapshot
MMP9 regulates the cellular response to inflammation after skeletal injury
inferred← citeshttps://doi.org/10.1016/j.bone.2012.12.008openalex-snapshot
Glast-expressing progenitor cells contribute to heterotopic ossification
inferred← citeshttps://doi.org/10.1016/j.bone.2013.03.020openalex-snapshot
Preoperative irradiation for the prevention of heterotopic ossification induces local inflammation in humans
inferred← citeshttps://doi.org/10.1016/j.bone.2015.12.010openalex-snapshot
Osteogenic potential of alpha smooth muscle actin expressing muscle resident progenitor cells
inferred← citeshttps://doi.org/10.1016/j.bone.2016.01.004openalex-snapshot
Inhibition of TGFβ signaling decreases osteogenic differentiation of fibrodysplasia ossificans progressiva fibroblasts in a novel in vitro model of the disease
inferred← citeshttps://doi.org/10.1016/j.bone.2016.02.008openalex-snapshot
Effectiveness and mode of action of a combination therapy for heterotopic ossification with a retinoid agonist and an anti-inflammatory agent
inferred← citeshttps://doi.org/10.1016/j.bone.2016.10.003openalex-snapshot
Hematopoietic derived cells do not contribute to osteogenesis as osteoblasts
inferred← citeshttps://doi.org/10.1016/j.bone.2017.05.015openalex-snapshot
Neurological heterotopic ossification: Current understanding and future directions
inferred← citeshttps://doi.org/10.1016/j.bone.2017.06.011openalex-snapshot
The obligatory role of Activin A in the formation of heterotopic bone in Fibrodysplasia Ossificans Progressiva
inferred← citeshttps://doi.org/10.1016/j.bone.2017.06.014openalex-snapshot
Gli1-labeled adult mesenchymal stem/progenitor cells and hedgehog signaling contribute to endochondral heterotopic ossification
inferred← citeshttps://doi.org/10.1016/j.bone.2017.08.001openalex-snapshot
Shared ACVR1 mutations in FOP and DIPG: Opportunities and challenges in extending biological and clinical implications across rare diseases
inferred← citeshttps://doi.org/10.1016/j.bone.2017.09.019openalex-snapshot
Heterotopic ossification and the elucidation of pathologic differentiation
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Stem cells and heterotopic ossification: Lessons from animal models
inferred← citeshttps://doi.org/10.1016/j.bone.2020.115473openalex-snapshot
Activin A does not drive post-traumatic heterotopic ossification
inferred← citeshttps://doi.org/10.1016/j.bone.2020.115765openalex-snapshot
A review of the biomarkers and in vivo models for the diagnosis and treatment of heterotopic ossification following blast and trauma-induced injuries
inferred← citeshttps://doi.org/10.1016/j.bone.2022.116655openalex-snapshot
Pathogenesis of acquired heterotopic ossification: Risk factors, cellular mechanisms, and therapeutic implications
inferred← citeshttps://doi.org/10.1016/j.carpath.2010.03.001openalex-snapshot
Calcification after myocardial infarction is independent of amniotic fluid stem cell injection
inferred← citeshttps://doi.org/10.1016/j.celrep.2024.114049openalex-snapshot
Vegfc-expressing cells form heterotopic bone after musculoskeletal injury
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2009.10.006openalex-snapshot
The FOP metamorphogene encodes a novel type I receptor that dysregulates BMP signaling
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2015.12.007openalex-snapshot
Common mutations in ALK2/ACVR1, a multi-faceted receptor, have roles in distinct pediatric musculoskeletal and neural orphan disorders
inferred← citeshttps://doi.org/10.1016/j.humpath.2024.02.006openalex-snapshot
Biological background of colorectal polyps and carcinomas with heterotopic ossification: A national study and literature review
inferred← citeshttps://doi.org/10.1016/j.joca.2014.12.015openalex-snapshot
Soft tissue ossification and condylar cartilage degeneration following TMJ disc perforation in a rabbit pilot study
inferred← citeshttps://doi.org/10.1016/j.jot.2019.06.001openalex-snapshot
Muscle injury promotes heterotopic ossification by stimulating local bone morphogenetic protein-7 production
inferred← citeshttps://doi.org/10.1016/j.mattod.2015.10.008openalex-snapshot
Calcium phosphates in biomedical applications: materials for the future?
inferred← citeshttps://doi.org/10.1016/j.msec.2021.111948openalex-snapshot
Coupling between macrophage phenotype, angiogenesis and bone formation by calcium phosphates
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2017.02.017openalex-snapshot
Macrophages and skeletal health
inferred← citeshttps://doi.org/10.1016/j.radcr.2024.04.019openalex-snapshot
Fibrodysplasia ossificans progressiva: Two case reports
inferred← citeshttps://doi.org/10.1016/j.reuma.2014.05.001openalex-snapshot
¿Es la «fibrodisplasia osificante progresiva» una enfermedad de origen vascular? Un modelo patogénico innovador
inferred← citeshttps://doi.org/10.1016/j.reumae.2014.05.003openalex-snapshot
Is “Fibrodysplasia Ossificans Progressiva” a Vascular Disease? A Groundbreaking Pathogenic Model
inferred← citeshttps://doi.org/10.1016/j.semcdb.2015.12.013openalex-snapshot
Granting immunity to FOP and catching heterotopic ossification in the Act
inferred← citeshttps://doi.org/10.1016/j.yexcr.2015.10.015openalex-snapshot
Macrophages derived from THP-1 promote the osteogenic differentiation of mesenchymal stem cells through the IL-23/IL-23R/β-catenin pathway
inferred← citeshttps://doi.org/10.1038/s41374-019-0367-xopenalex-snapshot
Macrophage-derived neurotrophin-3 promotes heterotopic ossification in rats
inferred← citeshttps://doi.org/10.1038/s41413-019-0074-7openalex-snapshot
Inhibition of immune checkpoints prevents injury-induced heterotopic ossification
inferred← citeshttps://doi.org/10.1038/s41413-022-00216-xopenalex-snapshot
Neuron-to-vessel signaling is a required feature of aberrant stem cell commitment after soft tissue trauma
inferred← citeshttps://doi.org/10.1038/s41413-022-00232-xopenalex-snapshot
Fetuin-A is an immunomodulator and a potential therapeutic option in BMP4-dependent heterotopic ossification and associated bone mass loss
inferred← citeshttps://doi.org/10.1038/s41467-019-14172-4openalex-snapshot
Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing
inferred← citeshttps://doi.org/10.1038/s41467-021-24643-2openalex-snapshot
Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway
inferred← citeshttps://doi.org/10.1038/s41467-021-25143-zopenalex-snapshot
NGF-TrkA signaling dictates neural ingrowth and aberrant osteochondral differentiation after soft tissue trauma
inferred← citeshttps://doi.org/10.1038/s41536-021-00178-4openalex-snapshot
Macrophages in heterotopic ossification: from mechanisms to therapy
inferred← citeshttps://doi.org/10.1038/s41598-019-56484-xopenalex-snapshot
Increase in bone metabolic markers and circulating osteoblast-lineage cells after orthognathic surgery
inferred← citeshttps://doi.org/10.1055/s-0040-1721378openalex-snapshot
Tumor-like Lesions of Bone and Soft Tissues and Imaging Tips for Differential Diagnosis
inferred← citeshttps://doi.org/10.1080/23320885.2024.2309970openalex-snapshot
Ossifying fasciitis of the proximal lower extremity
inferred← citeshttps://doi.org/10.1089/neur.2021.0072openalex-snapshot
Lymphocytes Are Not Required for Neurogenic Heterotopic Ossification Development after Spinal Cord Injury
inferred← citeshttps://doi.org/10.1089/zeb.2016.1398openalex-snapshot
A Zebrafish Model of Human Fibrodysplasia Ossificans Progressiva
inferred← citeshttps://doi.org/10.1089/zeb.2018.1611openalex-snapshot
Injury of Adult Zebrafish Expressing Acvr1l Q204D Does Not Result in Heterotopic Ossification
inferred← citeshttps://doi.org/10.1093/rb/rbx024openalex-snapshot
The material and biological characteristics of osteoinductive calcium phosphate ceramics
inferred← citeshttps://doi.org/10.1097/dad.0b013e31820d770bopenalex-snapshot
Panniculitis Ossificans Traumatica of the Lower Leg
inferred← citeshttps://doi.org/10.1097/sla.0000000000005940openalex-snapshot
Neutrophil and NETosis Modulation in Traumatic Heterotopic Ossification
inferred← citeshttps://doi.org/10.1097/ta.0000000000000883openalex-snapshot
Trauma-induced heterotopic bone formation and the role of the immune system
inferred← citeshttps://doi.org/10.1101/2021.01.31.429058openalex-snapshot
Hedgehog pathway inhibitors significantly reduce the formation of heterotopic ossification in a direct trauma/burn mouse model
inferred← citeshttps://doi.org/10.1101/2024.12.01.626232openalex-snapshot
A gene co-expression network-based analysis of mesenchymal stromal cells reveals novel genes and molecular pathways underlying heterotopic ossification
inferred← citeshttps://doi.org/10.1101/871574openalex-snapshot
Regulation of heterotopic ossification through local inflammatory monocytes in a mouse model of aberrant wound healing
inferred← citeshttps://doi.org/10.1111/1440-1681.13676openalex-snapshot
Palovarotene inhibits the NF‐κB signalling pathway to prevent heterotopic ossification
inferred← citeshttps://doi.org/10.1111/febs.13667openalex-snapshot
SMAD 7 prevents heterotopic ossification in a rat Achilles tendon injury model via regulation of endothelial–mesenchymal transition
inferred← citeshttps://doi.org/10.1111/j.1365-2613.2012.00829.xopenalex-snapshot
Heterotopic mineralization (ossification or calcification) in tendinopathy or following surgical tendon trauma
inferred← citeshttps://doi.org/10.1111/j.1749-6632.2011.06195.xopenalex-snapshot
Fibrodysplasia ossificans progressiva: a blueprint for metamorphosis
inferred← citeshttps://doi.org/10.1111/jcmm.14150openalex-snapshot
Neurotrophin‐3 acts on the endothelial‐mesenchymal transition of heterotopic ossification in rats
inferred← citeshttps://doi.org/10.1111/jcmm.15735openalex-snapshot
Mechanism of traumatic heterotopic ossification: In search of injury‐induced osteogenic factors
inferred← citeshttps://doi.org/10.1111/jcmm.15793openalex-snapshot
Pyrophosphate therapy prevents trauma‐induced calcification in the mouse model of neurogenic heterotopic ossification
inferred← citeshttps://doi.org/10.1136/bcr-2018-227992openalex-snapshot
Bilateral hamstring origin calcification: rare presentation of Gitelman syndrome
inferred← citeshttps://doi.org/10.1136/bcr-2019-233504openalex-snapshot
Surgical excision of post-traumatic myositis ossificans of the adductor longus in a football player
inferred← citeshttps://doi.org/10.1152/ajpendo.00253.2015openalex-snapshot
Stromal cell-derived factor-1 mediates changes of bone marrow stem cells during the bone repair process
inferred← citeshttps://doi.org/10.1152/ajpheart.00100.2019openalex-snapshot
Adaptive immune cells in calcific aortic valve disease
inferred← citeshttps://doi.org/10.1152/physrev.00036.2016openalex-snapshot
Osteoimmunology: The Conceptual Framework Unifying the Immune and Skeletal Systems
inferred← citeshttps://doi.org/10.1155/2011/309287openalex-snapshot
Animal Models of Typical Heterotopic Ossification
inferred← citeshttps://doi.org/10.1161/atvbaha.111.234724openalex-snapshot
Role for Circulating Osteogenic Precursor Cells in Aortic Valvular Disease
inferred← citeshttps://doi.org/10.1166/jbn.2021.3019openalex-snapshot
RNA Sequencing Evidences the Prevention of Oxidative Stress is Effective in Injury-Induced Heterotopic Ossification Treatment
inferred← citeshttps://doi.org/10.1172/jci.insight.158996openalex-snapshot
Contemporary perspectives on heterotopic ossification
inferred← citeshttps://doi.org/10.1172/jci153795openalex-snapshot
An anti-ACVR1 antibody exacerbates heterotopic ossification by fibro-adipogenic progenitors in fibrodysplasia ossificans progressiva mice
inferred← citeshttps://doi.org/10.1177/2325967117718780openalex-snapshot
Unsupervised Exercise–Induced Myositis Ossificans in the Brachialis Muscle of a Young Healthy Male: A Case Report
inferred← citeshttps://doi.org/10.1182/blood-2009-11-252841openalex-snapshot
FLIP: a novel regulator of macrophage differentiation and granulocyte homeostasis
inferred← citeshttps://doi.org/10.1186/1423-0127-18-92openalex-snapshot
Inhibition of BMP signaling in P-Cadherin positive hair progenitor cells leads to trichofolliculoma-like hair follicle neoplasias
inferred← citeshttps://doi.org/10.1186/s13018-025-06435-2openalex-snapshot
Single cell RNA-seq analysis associates Osm signaling in macrophages with osteogenic differentiation during heterotopic ossification
inferred← citeshttps://doi.org/10.1186/s13256-022-03664-5openalex-snapshot
Myositis ossificans circumscripta after surgery and radiotherapy and during sunitinib treatment: a case report
inferred← citeshttps://doi.org/10.1186/s13287-018-1107-7openalex-snapshot
BMP-dependent, injury-induced stem cell niche as a mechanism of heterotopic ossification
inferred← citeshttps://doi.org/10.1186/s13287-026-04916-7openalex-snapshot
M2 macrophages promote heterotopic ossification through MSX2 binding to LEF1-mediated endothelial-mesenchymal transition
inferred← citeshttps://doi.org/10.11909/j.issn.1671-5411.2016.01.015openalex-snapshot
Circulating CD14(+) monocytes in patients with aortic stenosis.
inferred← citeshttps://doi.org/10.1242/dmm.010280openalex-snapshot
Fibrodysplasia ossificans progressiva: mechanisms and models of skeletal metamorphosis
inferred← citeshttps://doi.org/10.1242/dmm.023929openalex-snapshot
High-throughput screening for modulators of ACVR1 transcription: discovery of potential therapeutics for fibrodysplasia ossificans progressiva
inferred← citeshttps://doi.org/10.1242/dmm.050724openalex-snapshot
Genetic regulation of injury-induced heterotopic ossification in adult zebrafish
inferred← citeshttps://doi.org/10.1249/jsr.0000000000000904openalex-snapshot
Bilateral Post Traumatic Myositis Ossificans of Adductor Longus in a Young Soccer Player: A Case Report and Literature Review
inferred← citeshttps://doi.org/10.1258/om.2011.110042openalex-snapshot
Pregnancy in fibrodysplasia ossificans progressiva
inferred← citeshttps://doi.org/10.12677/acm.2024.1472032openalex-snapshot
Research Progress of Ectopic Ossification after Hip Joint Operation
inferred← citeshttps://doi.org/10.12998/wjcc.v10.i9.2899openalex-snapshot
Giant nontraumatic myositis ossificans in a child: A case report
inferred← citeshttps://doi.org/10.12998/wjcc.v10.i9.2901openalex-snapshot
Giant nontraumatic myositis ossificans in a child: A case report
inferred← citeshttps://doi.org/10.1302/2046-3758.1010.bjr-2020-0454.r1openalex-snapshot
BRD4promotes heterotopic ossification through upregulation of LncRNA MANCR
inferred← citeshttps://doi.org/10.13107/jocr.2022.v12.i10.3362openalex-snapshot
A Rare Presentation of Myositis Ossificans in a Diabetic Individual
inferred← citeshttps://doi.org/10.1371/journal.pone.0056641openalex-snapshot
Osteogenic Differentiation Capacity of Human Skeletal Muscle-Derived Progenitor Cells
inferred← citeshttps://doi.org/10.1371/journal.pone.0159624openalex-snapshot
Validation of a Radiography-Based Quantification Designed to Longitudinally Monitor Soft Tissue Calcification in Skeletal Muscle
inferred← citeshttps://doi.org/10.14264/uql.2015.753openalex-snapshot
Understanding heterotopic ossification after spinal cord injury
inferred← citeshttps://doi.org/10.14670/hh-29.1281openalex-snapshot
Molecular and cellular mechanisms of heterotopic ossification.
inferred← citeshttps://doi.org/10.1517/21678707.2013.825208openalex-snapshot
From mysteries to medicines: drug development for fibrodysplasia ossificans progressiva
inferred← citeshttps://doi.org/10.1530/eor-23-0207openalex-snapshot
Research trends and hotspots of myositis ossificans: a bibliometric analysis from 1993 to 2022
inferred← citeshttps://doi.org/10.1615/critreveukargeneexpr.v20.i2.70openalex-snapshot
Circulating Osteogenic Precursor Cells
inferred← citeshttps://doi.org/10.17555/jvc.2024.41.4.207openalex-snapshot
A Case of Canine Colorectal Carcinoma In Situ with Regulatory T Cell Infiltration
inferred← citeshttps://doi.org/10.17816/gc678636openalex-snapshot
Fibrodysplasia ossificans progressiva: molecular genetic causes, clinical and morphological characteristics, and therapeutic approaches to treatment
inferred← citeshttps://doi.org/10.2106/jbjs.i.00319openalex-snapshot
Whatʼs New in Orthopaedic Rehabilitation
inferred← citeshttps://doi.org/10.2106/jbjs.n.01056openalex-snapshot
Heterotopic Ossification: Basic-Science Principles and Clinical Correlates
inferred← citeshttps://doi.org/10.22203/ecm.v021a31openalex-snapshot
Osteoinductive biomaterials: current knowledge of properties, experimental models and biological mechanisms
inferred← citeshttps://doi.org/10.2298/jsc190304060gopenalex-snapshot
Antiosteogenic effect of arsenic trioxide, cholecalciferol, lovastatin or their combination in vitro
inferred← citeshttps://doi.org/10.24275/uami.n583xv01bopenalex-snapshot
Ingeniería Tisular para la formación de Hueso Autólogo útil en Autotrasplante
inferred← citeshttps://doi.org/10.3109/02699052.2011.571228openalex-snapshot
Subdural hygroma-related heterotopic ossification in a patient with a stroke: A case report
inferred← citeshttps://doi.org/10.32657/10356/179501openalex-snapshot
Heterotopic ossification secondary to injury: insights from a novel zebrafish model
inferred← citeshttps://doi.org/10.3389/fimmu.2019.01640openalex-snapshot
Severe Heterotopic Ossification in the Skeletal Muscle and Endothelial Cells Recruitment to Chondrogenesis Are Enhanced by Monocyte/Macrophage Depletion
inferred← citeshttps://doi.org/10.3389/fimmu.2020.00058openalex-snapshot
Osteoimmunology: A Current Update of the Interplay Between Bone and the Immune System
inferred← citeshttps://doi.org/10.3389/fnagi.2014.00245openalex-snapshot
Pericytes: multitasking cells in the regeneration of injured, diseased, and aged skeletal muscle
inferred← citeshttps://doi.org/10.3389/fphar.2024.1434146openalex-snapshot
Single-cell RNA sequencing uncovers cellular heterogeneity and the progression of heterotopic ossification of the elbow
inferred← citeshttps://doi.org/10.3390/antiox11112265openalex-snapshot
Hedgehog Signalling Contributes to Trauma-Induced Tendon Heterotopic Ossification and Regulates Osteogenesis through Antioxidant Pathway in Tendon-Derived Stem Cells
inferred← citeshttps://doi.org/10.3390/biom14030349openalex-snapshot
Intersections of Fibrodysplasia Ossificans Progressiva and Traumatic Heterotopic Ossification
inferred← citeshttps://doi.org/10.3390/biom14030357openalex-snapshot
Immunologic Aspects in Fibrodysplasia Ossificans Progressiva
inferred← citeshttps://doi.org/10.3390/biomedicines9060630openalex-snapshot
MyD88 Is Not Required for Muscle Injury-Induced Endochondral Heterotopic Ossification in a Mouse Model of Fibrodysplasia Ossificans Progressiva
inferred← citeshttps://doi.org/10.3390/cells14191491openalex-snapshot
A Novel Human Stem Cell Culture Model for Severe Traumatic Brain Injury Reflecting Sexual Dimorphism in Heterotopic Ossification
inferred← citeshttps://doi.org/10.3390/cells9061324openalex-snapshot
The Survey of Cells Responsible for Heterotopic Ossification Development in Skeletal Muscles—Human and Mouse Models
inferred← citeshttps://doi.org/10.3390/ijms19040989openalex-snapshot
The Horizon of a Therapy for Rare Genetic Diseases: A “Druggable” Future for Fibrodysplasia Ossificans Progressiva
inferred← citeshttps://doi.org/10.3390/ijms23136983openalex-snapshot
Pathophysiology and Emerging Molecular Therapeutic Targets in Heterotopic Ossification
inferred← citeshttps://doi.org/10.3390/ijms23168893openalex-snapshot
Nervous System-Driven Osseointegration
inferred← citeshttps://doi.org/10.3410/f.737330682.793579725openalex-snapshot
Faculty Opinions recommendation of Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing.
inferred← citeshttps://doi.org/10.36106/ijar/6900985openalex-snapshot
STIFF ELBOW!! POST TRAUMATIC MYOSITIS OSSIFICANS? A CASE REPORT
inferred← citeshttps://doi.org/10.3928/01477447-20140430-07openalex-snapshot
Evaluation of the Cellular Origins of Heterotopic Ossification
inferred← citeshttps://doi.org/10.3978/j.issn.2305-5839.2015.07.27openalex-snapshot
Picking a bone with heterotopic ossification: translational progress current and future.
inferred← citeshttps://doi.org/10.5435/jaaos-d-14-00269openalex-snapshot
Myositis Ossificans
inferred← citeshttps://doi.org/10.62347/aapm9027openalex-snapshot
Metformin alleviates genetic and traumatic heterotopic ossification by inhibiting infiltration and mitochondrial metabolism of myeloid cells
inferred← citeshttps://doi.org/10.7150/ijms.58428openalex-snapshot
Changes of Migration, Immunoregulation and Osteogenic Differentiation of Mesenchymal Stem Cells in Different Stages of Inflammation
inferred← citeshttps://doi.org/10.7507/1002-1892.202110078openalex-snapshot
[Research progress of traumatic heterotopic ossification].
inferred← citeshttps://doi.org/10.7554/elife.91779openalex-snapshot
PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification
inferred← citeshttps://doi.org/10.7554/elife.91779.1openalex-snapshot
PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification
inferred← citeshttps://doi.org/10.7554/elife.91779.2openalex-snapshot
PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification
inferred← citeshttps://doi.org/10.7554/elife.91779.2.sa0openalex-snapshot
Reviewer #2 (Public Review): PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification
inferred← citeshttps://doi.org/10.7554/elife.91779.2.sa1openalex-snapshot
Reviewer #1 (Public Review): PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification
inferred← citeshttps://doi.org/10.7554/elife.91779.2.sa2openalex-snapshot
eLife Assessment: PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification
inferred← citeshttps://doi.org/10.7554/elife.91779.2.sa3openalex-snapshot
Author response: PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification
inferred← citeshttps://doi.org/10.7554/elife.91779.3openalex-snapshot
PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification
inferred← citeshttps://doi.org/10.7554/elife.91779.4openalex-snapshot
PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification
inferred← citeshttps://doi.org/10.7759/cureus.14328openalex-snapshot
Multifocal Post-Traumatic Myositis Ossificans Circumscripta in a Young Male Following a Motor Vehicle Accident: A Review of Imaging and Clinical Presentation
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.