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G Protein-Coupled Bile Acid Receptor TGR5 Activation Inhibits Kidney Disease in Obesity and Diabetes
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1001/jama.2011.861openalex-snapshot
Temporal Trends in the Prevalence of Diabetic Kidney Disease in the United States
inferredcites →https://doi.org/10.1002/hep.21458openalex-snapshot
The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells
inferredcites →https://doi.org/10.1007/978-1-60761-756-3_16openalex-snapshot
Measurement of Mitochondrial ROS Production
inferredcites →https://doi.org/10.1016/j.amepre.2012.02.001openalex-snapshot
Implications of the Energy Gap for the Prevention and Treatment of Childhood Obesity
inferredcites →https://doi.org/10.1016/j.bbamcr.2010.09.019openalex-snapshot
Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network
inferredcites →https://doi.org/10.1016/j.bbrc.2005.01.139openalex-snapshot
Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1
inferredcites →https://doi.org/10.1016/j.bpj.2012.03.016openalex-snapshot
Characterization of Cholesterol Crystals in Atherosclerotic Plaques Using Stimulated Raman Scattering and Second-Harmonic Generation Microscopy
inferredcites →https://doi.org/10.1016/j.cellsig.2007.04.009openalex-snapshot
Oxyl radicals, redox-sensitive signalling cascades and antioxidants
inferredcites →https://doi.org/10.1016/j.cmet.2009.08.001openalex-snapshot
TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis
inferredcites →https://doi.org/10.1016/j.cmet.2010.08.015openalex-snapshot
Insulin Signaling to the Glomerular Podocyte Is Critical for Normal Kidney Function
inferredcites →https://doi.org/10.1016/j.cmet.2010.11.015openalex-snapshot
Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation
inferredcites →https://doi.org/10.1016/j.cmet.2011.11.006openalex-snapshot
TGR5 Activation Inhibits Atherosclerosis by Reducing Macrophage Inflammation and Lipid Loading
inferredcites →https://doi.org/10.1016/j.drudis.2009.02.005openalex-snapshot
TGR5: an emerging bile acid G-protein-coupled receptor target for the potential treatment of metabolic disorders
inferredcites →https://doi.org/10.1016/j.exger.2012.08.007openalex-snapshot
SIRT3 regulation of mitochondrial oxidative stress
inferredcites →https://doi.org/10.1016/j.mito.2013.04.002openalex-snapshot
Dual control of mitochondrial biogenesis by sirtuin 1 and sirtuin 3
inferredcites →https://doi.org/10.1016/j.molcel.2010.12.013openalex-snapshot
Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress
inferredcites →https://doi.org/10.1016/j.semnephrol.2007.01.008openalex-snapshot
Regulation of Transforming Growth Factor β in Diabetic Nephropathy: Implications for Treatment
inferredcites →https://doi.org/10.1016/j.semnephrol.2007.01.009openalex-snapshot
The Renin-Angiotensin System and Diabetic Nephropathy
inferredcites →https://doi.org/10.1016/j.tem.2008.07.005openalex-snapshot
ERRα: a metabolic function for the oldest orphan
inferredcites →https://doi.org/10.1016/j.tem.2012.07.008openalex-snapshot
The evolving role of mitochondria in metabolism
inferredcites →https://doi.org/10.1016/s0006-291x(02)02550-0openalex-snapshot
Identification of membrane-type receptor for bile acids (M-BAR)
inferredcites →https://doi.org/10.1016/s0092-8674(00)00062-3openalex-snapshot
Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis
inferredcites →https://doi.org/10.1021/jm070633popenalex-snapshot
Nongenomic Actions of Bile Acids. Synthesis and Preliminary Characterization of 23- and 6,23-Alkyl-Substituted Bile Acid Derivatives as Selective Modulators for the G-Protein Coupled Receptor TGR5
inferredcites →https://doi.org/10.1038/ki.1994.80openalex-snapshot
Structural-functional correlations of diabetic nephropathy
inferredcites →https://doi.org/10.1038/nature04330openalex-snapshot
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
inferredcites →https://doi.org/10.1038/nrd2619openalex-snapshot
Targeting bile-acid signalling for metabolic diseases
inferredcites →https://doi.org/10.1038/nrm3293openalex-snapshot
Sirtuins as regulators of metabolism and healthspan
inferredcites →https://doi.org/10.1038/nrm3311openalex-snapshot
AMPK: a nutrient and energy sensor that maintains energy homeostasis
inferredcites →https://doi.org/10.1038/nrneph.2009.184openalex-snapshot
An update on the lipid nephrotoxicity hypothesis
inferredcites →https://doi.org/10.1046/j.1523-1755.2001.0590041498.xopenalex-snapshot
Obesity-related glomerulopathy: An emerging epidemic
inferredcites →https://doi.org/10.1074/jbc.m110650200openalex-snapshot
Role of Sterol Regulatory Element-binding Protein 1 in Regulation of Renal Lipid Metabolism and Glomerulosclerosis in Diabetes Mellitus
inferredcites →https://doi.org/10.1074/jbc.m209706200openalex-snapshot
A G Protein-coupled Receptor Responsive to Bile Acids
inferredcites →https://doi.org/10.1074/jbc.m500801200openalex-snapshot
Diet-induced Obesity in C57BL/6J Mice Causes Increased Renal Lipid Accumulation and Glomerulosclerosis via a Sterol Regulatory Element-binding Protein-1c-dependent Pathway
inferredcites →https://doi.org/10.1093/ndt/gfr061openalex-snapshot
TGF-beta1 reduces Wilms' tumor suppressor gene expression in podocytes
inferredcites →https://doi.org/10.1097/mnh.0b013e3283374c09openalex-snapshot
Scope and mechanisms of obesity-related renal disease
inferredcites →https://doi.org/10.1097/mnh.0b013e32833aa4acopenalex-snapshot
Renal lipid metabolism and lipotoxicity
inferredcites →https://doi.org/10.1111/j.1523-1755.2005.00161.xopenalex-snapshot
Limitation of podocyte proliferation improves renal function in experimental crescentic glomerulonephritis
inferredcites →https://doi.org/10.1111/j.1523-1755.2005.00733.xopenalex-snapshot
Role of altered renal lipid metabolism and the sterol regulatory element binding proteins in the pathogenesis of age-related renal disease
inferredcites →https://doi.org/10.1111/j.2040-1124.2010.00047.xopenalex-snapshot
Mitochondrial metabolism and diabetes
inferredcites →https://doi.org/10.1124/jpet.114.214650openalex-snapshot
Semisynthetic Bile Acid FXR and TGR5 Agonists: Physicochemical Properties, Pharmacokinetics, and Metabolism in the Rat
inferredcites →https://doi.org/10.1124/mol.110.064501openalex-snapshot
Functional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 Agonist
inferredcites →https://doi.org/10.1128/mcb.24.20.9079-9091.2004openalex-snapshot
Estrogen-Related Receptor α Directs Peroxisome Proliferator-Activated Receptor α Signaling in the Transcriptional Control of Energy Metabolism in Cardiac and Skeletal Muscle
inferredcites →https://doi.org/10.1152/ajpcell.00563.2009openalex-snapshot
Bioenergetic characterization of mouse podocytes
inferredcites →https://doi.org/10.1152/ajprenal.00068.2011openalex-snapshot
The Western-style diet: a major risk factor for impaired kidney function and chronic kidney disease
inferredcites →https://doi.org/10.1152/ajprenal.00338.2010openalex-snapshot
Vitamin D receptor agonist doxercalciferol modulates dietary fat-induced renal disease and renal lipid metabolism
inferredcites →https://doi.org/10.1152/ajprenal.00404.2009openalex-snapshot
The farnesoid X receptor modulates renal lipid metabolism and diet-induced renal inflammation, fibrosis, and proteinuria
inferredcites →https://doi.org/10.1152/ajprenal.00597.2009openalex-snapshot
Proteomic analysis identifies insulin-like growth factor-binding protein-related protein-1 as a podocyte product
inferredcites →https://doi.org/10.1152/physrev.00022.2011openalex-snapshot
Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism
inferredcites →https://doi.org/10.1159/000151770openalex-snapshot
Tetracycline-Inducible Gene Expression in Conditionally Immortalized Mouse Podocytes
inferredcites →https://doi.org/10.1172/jci27794openalex-snapshot
PGC-1 coactivators: inducible regulators of energy metabolism in health and disease
inferredcites →https://doi.org/10.1172/jci29812openalex-snapshot
Deiodinases: implications of the local control of thyroid hormone action
inferredcites →https://doi.org/10.1172/jci66218openalex-snapshot
AMPK dysregulation promotes diabetes-related reduction of superoxide and mitochondrial function
inferredcites →https://doi.org/10.1172/jci72271openalex-snapshot
Molecular mechanisms of diabetic kidney disease
inferredcites →https://doi.org/10.1172/jci72326openalex-snapshot
Mitochondrial ROS deficiency and diabetic complications: AMP[K]-lifying the adaptation to hyperglycemia
inferredcites →https://doi.org/10.1177/1470320314543910openalex-snapshot
ACE-inhibition increases podocyte number in experimental glomerular disease independent of proliferation
inferredcites →https://doi.org/10.1186/1478-7954-8-29openalex-snapshot
Projection of the year 2050 burden of diabetes in the US adult population: dynamic modeling of incidence, mortality, and prediabetes prevalence
inferredcites →https://doi.org/10.1194/jlr.m003616openalex-snapshot
Multimodal CARS microscopy determination of the impact of diet on macrophage infiltration and lipid accumulation on plaque formation in ApoE-deficient mice
inferredcites →https://doi.org/10.1194/jlr.m018077openalex-snapshot
Identification of cholesterol crystals in plaques of atherosclerotic mice using hyperspectral CARS imaging
inferredcites →https://doi.org/10.1194/jlr.p040501openalex-snapshot
Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathy
inferredcites →https://doi.org/10.1210/er.2006-0037openalex-snapshot
Peroxisome Proliferator-Activated Receptor γ Coactivator 1 Coactivators, Energy Homeostasis, and Metabolism
inferredcites →https://doi.org/10.1371/journal.pone.0075547openalex-snapshot
Proximal Tubular Hypertrophy and Enlarged Glomerular and Proximal Tubular Urinary Space in Obese Subjects with Proteinuria
inferredcites →https://doi.org/10.1371/journal.pone.0108270openalex-snapshot
Dual Activation of the Bile Acid Nuclear Receptor FXR and G-Protein-Coupled Receptor TGR5 Protects Mice against Atherosclerosis
inferredcites →https://doi.org/10.1542/peds.2011-1082openalex-snapshot
Prevalence of Cardiovascular Disease Risk Factors Among US Adolescents, 1999−2008
inferredcites →https://doi.org/10.1681/asn.2004080701openalex-snapshot
Calorie Restriction Modulates Renal Expression of Sterol Regulatory Element Binding Proteins, Lipid Accumulation, and Age-Related Renal Disease
inferredcites →https://doi.org/10.1681/asn.2008080879openalex-snapshot
Reduction of Stat3 Activity Attenuates HIV-Induced Kidney Injury
inferredcites →https://doi.org/10.1681/asn.2010040354openalex-snapshot
Risk for ESRD in Type 1 Diabetes Remains High Despite Renoprotection
inferredcites →https://doi.org/10.1681/asn.2013020126openalex-snapshot
Metabolomics Reveals Signature of Mitochondrial Dysfunction in Diabetic Kidney Disease
inferredcites →https://doi.org/10.1681/asn.v133630openalex-snapshot
A Conditionally Immortalized Human Podocyte Cell Line Demonstrating Nephrin and Podocin Expression
inferredcites →https://doi.org/10.2174/1389450111314060002openalex-snapshot
Sirtuins as Possible Drug Targets in Type 2 Diabetes
inferredcites →https://doi.org/10.2215/cjn.02180311openalex-snapshot
Metabolic Syndrome and Kidney Disease
inferredcites →https://doi.org/10.2337/db05-0509openalex-snapshot
Evidence for a Mitochondrial Regulatory Pathway Defined by Peroxisome Proliferator–Activated Receptor-γ Coactivator-1α, Estrogen-Related Receptor-α, and Mitofusin 2
inferredcites →https://doi.org/10.2337/db06-1642openalex-snapshot
Farnesoid X Receptor Modulates Renal Lipid Metabolism, Fibrosis, and Diabetic Nephropathy
inferredcites →https://doi.org/10.2337/db08-0057openalex-snapshot
Oxidative Stress as a Major Culprit in Kidney Disease in Diabetes
inferredcites →https://doi.org/10.2337/db10-0019openalex-snapshot
Diabetic Nephropathy Is Accelerated by Farnesoid X Receptor Deficiency and Inhibited by Farnesoid X Receptor Activation in a Type 1 Diabetes Model
inferredcites →https://doi.org/10.2337/db10-1110openalex-snapshot
Dedifferentiation of Immortalized Human Podocytes in Response to Transforming Growth Factor-β
inferredcites →https://doi.org/10.2337/diabetes.54.8.2328openalex-snapshot
Regulation of Renal Lipid Metabolism, Lipid Accumulation, and Glomerulosclerosis in FVB db/db Mice With Type 2 Diabetes
inferredcites →https://doi.org/10.2353/ajpath.2010.090746openalex-snapshot
A Molecular Profile of Focal Segmental Glomerulosclerosis from Formalin-Fixed, Paraffin-Embedded Tissue
inferredcites →https://doi.org/10.3109/10799893.2014.959592openalex-snapshot
Estrogen-related receptor alpha and mitochondria: tale of the titans
inferredcites →https://doi.org/10.3945/ajcn.110.001917openalex-snapshot
Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis
inferredcites →https://doi.org/10.4161/cc.28189openalex-snapshot
Mitochondrial alteration in type 2 diabetes and obesity: An epigenetic link
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4135063openalex-extracted
Ginsenoside Compound K Through TGR5/YAP Signal To Increase Glucagon-Like Peptide-1 Release and L-Cell Number in db/db Mice
inferred← citeshttps://doi.org/10.1002/9780470747919.ch40openalex-snapshot
The Kidney in Liver Disease
inferred← citeshttps://doi.org/10.1002/9781119436812.ch49openalex-snapshot
The Kidney in Liver Disease
inferred← citeshttps://doi.org/10.1002/advs.77289openalex-snapshot
Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos
inferred← citeshttps://doi.org/10.1002/jbt.23047openalex-snapshot
Versatile role of sirtuins in metabolic disorders: From modulation of mitochondrial function to therapeutic interventions
inferred← citeshttps://doi.org/10.1002/jcb.28765openalex-snapshot
Retracted: The protective effects of TGR5 against ultraviolet B irradiation in epidermal stem cells
inferred← citeshttps://doi.org/10.1002/jcp.31110openalex-snapshot
Biofactors regulating mitochondrial function and dynamics in podocytes and podocytopathies
inferred← citeshttps://doi.org/10.1007/164_2019_230openalex-snapshot
Bile Acid-Activated Receptors: GPBAR1 (TGR5) and Other G Protein-Coupled Receptors
inferred← citeshttps://doi.org/10.1007/978-3-030-39684-8_4openalex-snapshot
Bile Acids and TGR5 (Gpbar1) Signaling
inferred← citeshttps://doi.org/10.1007/978-3-031-26163-3_10openalex-snapshot
Bile Acids Alter the Autophagy and Mitogenesis in Skeletal Muscle Cells
inferred← citeshttps://doi.org/10.1007/978-3-319-43359-2_4openalex-snapshot
Pathophysiology of Diabetic Nephropathy
inferred← citeshttps://doi.org/10.1007/978-3-319-53774-0_7openalex-snapshot
Bile Acid-Induced Liver Injury in Cholestasis
inferred← citeshttps://doi.org/10.1007/s00018-022-04658-8openalex-snapshot
Liver-derived metabolites as signaling molecules in fatty liver disease
inferred← citeshttps://doi.org/10.1007/s00109-019-01743-7openalex-snapshot
Role of sirtuin-1 in diabetic nephropathy
inferred← citeshttps://doi.org/10.1007/s00253-024-13007-7openalex-snapshot
Therapeutic applications of gut microbes in cardiometabolic diseases: current state and perspectives
inferred← citeshttps://doi.org/10.1007/s00424-026-03171-2openalex-snapshot
Active bile acid metabolism could contribute to muscle preservation in hibernating bears via the TGR5 pathway
inferred← citeshttps://doi.org/10.1007/s00726-021-03028-1openalex-snapshot
Bioactive peptide apelin rescues acute kidney injury by protecting the function of renal tubular mitochondria
inferred← citeshttps://doi.org/10.1007/s11255-022-03326-xopenalex-snapshot
Urine metabolomics reveals biomarkers and the underlying pathogenesis of diabetic kidney disease
inferred← citeshttps://doi.org/10.1007/s11906-025-01357-0openalex-snapshot
Novel Therapeutic Strategies for Obesity-Related Glomerulopathy
inferred← citeshttps://doi.org/10.1007/s12020-016-1032-4openalex-snapshot
TGR5 suppresses high glucose-induced upregulation of fibronectin and transforming growth factor-β1 in rat glomerular mesangial cells by inhibiting RhoA/ROCK signaling
inferred← citeshttps://doi.org/10.1016/b978-0-12-814118-2.00013-6openalex-snapshot
Sirtuins as key players in aging and kidney dysfunction
inferred← citeshttps://doi.org/10.1016/j.ajcnut.2023.08.023openalex-snapshot
Gut microbiota-derived secondary bile acids, bile acids receptor polymorphisms, and risk of cardiovascular disease in individuals with newly diagnosed type 2 diabetes: a cohort study
inferred← citeshttps://doi.org/10.1016/j.ajpath.2023.07.008openalex-snapshot
Estrogen-Related Receptor Agonism Reverses Mitochondrial Dysfunction and Inflammation in the Aging Kidney
inferred← citeshttps://doi.org/10.1016/j.aninu.2023.10.005openalex-snapshot
Leucine regulates lipid metabolism in adipose tissue through adipokine-mTOR-SIRT1 signaling pathway and bile acid–microbe axis in a finishing pig model
inferred← citeshttps://doi.org/10.1016/j.apsb.2026.04.014openalex-snapshot
The gut–liver axis in drug-induced liver injury (DILI): Interplay between gut microbiota, intestinal barrier, and immune system
inferred← citeshttps://doi.org/10.1016/j.arr.2026.103125openalex-snapshot
Nuclear receptors in age-related diseases: From mechanisms to drug discovery
inferred← citeshttps://doi.org/10.1016/j.bbadis.2017.08.016openalex-snapshot
Differential effects of FXR or TGR5 activation in cholangiocarcinoma progression
inferred← citeshttps://doi.org/10.1016/j.bbi.2020.09.016openalex-snapshot
INT-777 attenuates NLRP3-ASC inflammasome-mediated neuroinflammation via TGR5/cAMP/PKA signaling pathway after subarachnoid hemorrhage in rats
inferred← citeshttps://doi.org/10.1016/j.bbrc.2018.05.120openalex-snapshot
INT-777, a bile acid receptor agonist, extenuates pancreatic acinar cells necrosis in a mouse model of acute pancreatitis
inferred← citeshttps://doi.org/10.1016/j.bbrc.2022.10.074openalex-snapshot
Renoprotective effects of oleanolic acid and its possible mechanisms in rats with diabetic kidney disease
inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.151671openalex-snapshot
Role of bile acid-dependent Takeda G-coupled protein receptor 5 (TGR5) in regulating AMPK expression in human podocytes
inferred← citeshttps://doi.org/10.1016/j.bcp.2024.116313openalex-snapshot
Bile acid metabolism in health and ageing-related diseases
inferred← citeshttps://doi.org/10.1016/j.bioorg.2024.107132openalex-snapshot
Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.114465openalex-snapshot
The role of lipotoxicity in kidney disease: From molecular mechanisms to therapeutic prospects
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.114578openalex-snapshot
Relaxin elicits renoprotective actions accompanied by increasing bile acid levels in streptozotocin-induced diabetic mice
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.117010openalex-snapshot
Histone deacetylases and inhibitors in diabetes mellitus and its complications
inferred← citeshttps://doi.org/10.1016/j.cellsig.2026.112536openalex-snapshot
LCZ696 (Sac/Val) protects against high-fat diet-induced kidney injury in mice by targeting ROCK2 to suppress ROCK2/NF-κB signaling
inferred← citeshttps://doi.org/10.1016/j.celrep.2023.112851openalex-snapshot
The degradation of TGR5 mediated by Smurf1 contributes to diabetic nephropathy
inferred← citeshttps://doi.org/10.1016/j.celrep.2026.117499openalex-snapshot
A multi-organ metabolomics atlas reveals molecular dysregulations in Alzheimer’s disease mouse models
inferred← citeshttps://doi.org/10.1016/j.crmicr.2024.100315openalex-snapshot
Gut microbiota and bile acids: Metabolic interactions and impacts on diabetic kidney disease
inferred← citeshttps://doi.org/10.1016/j.ejphar.2016.11.037openalex-snapshot
Berberine enhances the AMPK activation and autophagy and mitigates high glucose-induced apoptosis of mouse podocytes
inferred← citeshttps://doi.org/10.1016/j.ejphar.2026.178597openalex-snapshot
TGR5 rescues renal ischemia-reperfusion injury by suppressing ferroptosis and cAMP/PKA/Nrf2 axis
inferred← citeshttps://doi.org/10.1016/j.ekir.2024.08.002openalex-snapshot
Role of Bile Acid Receptors in the Development and Function of Diabetic Nephropathy
inferred← citeshttps://doi.org/10.1016/j.expneurol.2020.113504openalex-snapshot
INT-777 prevents cognitive impairment by activating Takeda G protein-coupled receptor 5 (TGR5) and attenuating neuroinflammation via cAMP/ PKA/ CREB signaling axis in a rat model of sepsis
inferred← citeshttps://doi.org/10.1016/j.foodres.2022.111732openalex-snapshot
Noni (Morinda citrifolia L.) fruit phenolic extract supplementation ameliorates NAFLD by modulating insulin resistance, oxidative stress, inflammation, liver metabolism and gut microbiota
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2019.09.002openalex-snapshot
Activation of TGR5 with INT-777 attenuates oxidative stress and neuronal apoptosis via cAMP/PKCε/ALDH2 pathway after subarachnoid hemorrhage in rats
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2025.04.028openalex-snapshot
Dapagliflozin attenuates diabetes-induced podocyte lipotoxicity via ERRα-Mediated lipid metabolism
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2025.08.019openalex-snapshot
Novel coumarin derivative SZC-6 as an allosteric activator of SIRT3 alleviates diabetic kidney disease via the SIRT3-Foxo3a signaling axis
inferred← citeshttps://doi.org/10.1016/j.intimp.2022.109405openalex-snapshot
Ginsenoside compound K increases glucagon-like peptide-1 release and L-cell abundance in db/db mice through TGR5/YAP signaling
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.110670openalex-snapshot
Hyocholic acid retards renal fibrosis by regulating lipid metabolism and inflammatory response in a sheep model
inferred← citeshttps://doi.org/10.1016/j.isci.2025.113247openalex-snapshot
Role of gut microbiota and derived metabolites in cardiovascular diseases
inferred← citeshttps://doi.org/10.1016/j.jare.2024.11.003openalex-snapshot
Biological functions and pharmacological behaviors of bile acids in metabolic diseases
inferred← citeshttps://doi.org/10.1016/j.jbc.2022.102530openalex-snapshot
The role of FXR and TGR5 in reversing and preventing progression of Western diet–induced hepatic steatosis, inflammation, and fibrosis in mice
inferred← citeshttps://doi.org/10.1016/j.jff.2023.105817openalex-snapshot
Plantain flour – A beneficial material for the organ and transcriptional profile of kidney of diabetic rats
inferred← citeshttps://doi.org/10.1016/j.labinv.2024.100336openalex-snapshot
Bile Acid Receptor Agonist Reverses Transforming Growth Factor-β1–Mediated Fibrogenesis in Human Induced Pluripotent Stem Cells–Derived Kidney Organoids
inferred← citeshttps://doi.org/10.1016/j.lfs.2019.116941openalex-snapshot
Mitochondrial pyruvate carrier 2 mediates mitochondrial dysfunction and apoptosis in high glucose-treated podocytes
inferred← citeshttps://doi.org/10.1016/j.lfs.2026.124637openalex-snapshot
Organ crosstalk in kidney diseases: Insights from metabolic, hormonal and nervous regulation
inferred← citeshttps://doi.org/10.1016/j.livres.2018.09.008openalex-snapshot
Regulation of bile acid receptor activity
inferred← citeshttps://doi.org/10.1016/j.metabol.2023.155718openalex-snapshot
Interplay of lipid metabolism and inflammation in podocyte injury
inferred← citeshttps://doi.org/10.1016/j.metabol.2025.156133openalex-snapshot
TGR5 attenuates DOCA-salt hypertension through regulating histone H3K4 methylation of ENaC in the kidney
inferred← citeshttps://doi.org/10.1016/j.molmet.2024.102071openalex-snapshot
TGR5 receptors in SF1-expressing neurons of the ventromedial hypothalamus regulate glucose homeostasis
inferred← citeshttps://doi.org/10.1016/j.nbd.2024.106428openalex-snapshot
TGR5 signalling in heart and brain injuries: focus on metabolic and ischaemic mechanisms
inferred← citeshttps://doi.org/10.1016/j.obmed.2025.100652openalex-snapshot
Diabetes mellitus: Complications, emerging therapeutic targets, and evolving treatment approaches
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2022.108238openalex-snapshot
Bile acid metabolism and signaling, the microbiota, and metabolic disease
inferred← citeshttps://doi.org/10.1016/j.phrs.2016.05.035openalex-snapshot
TGR5 activation suppressed S1P/S1P2 signaling and resisted high glucose-induced fibrosis in glomerular mesangial cells
inferred← citeshttps://doi.org/10.1016/j.phrs.2019.104559openalex-snapshot
Gentiopicroside activates the bile acid receptor Gpbar1 (TGR5) to repress NF-kappaB pathway and ameliorate diabetic nephropathy
inferred← citeshttps://doi.org/10.1016/j.phrs.2024.107261openalex-snapshot
Sirtuin 3 in renal diseases and aging: From mechanisms to potential therapies
inferred← citeshttps://doi.org/10.1016/j.phrs.2024.107564openalex-snapshot
Beyond metabolic messengers: Bile acids and TGR5 as pharmacotherapeutic intervention for psychiatric disorders
inferred← citeshttps://doi.org/10.1016/j.prp.2026.156604openalex-snapshot
Rewiring lipid metabolism in diabetic kidney disease: Pathogenic networks and the therapeutic convergence of natural products
inferred← citeshttps://doi.org/10.1016/j.redox.2017.07.002openalex-snapshot
RETRACTED: Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc
inferred← citeshttps://doi.org/10.1016/j.redox.2020.101548openalex-snapshot
Isocitrate dehydrogenase 2 deficiency aggravates prolonged high-fat diet intake-induced hypertension
inferred← citeshttps://doi.org/10.1016/j.semnephrol.2021.06.004openalex-snapshot
Nuclear Receptors and Transcription Factors in Obesity-Related Kidney Disease
inferred← citeshttps://doi.org/10.1016/j.tiv.2026.106310openalex-snapshot
The bile acid chenodeoxycholic acid attenuates renal fibrosis in mouse precision-cut kidney slices
inferred← citeshttps://doi.org/10.1016/j.trsl.2023.11.002openalex-snapshot
Current updates on metabolites and its interlinked pathways as biomarkers for diabetic kidney disease: A systematic review
inferred← citeshttps://doi.org/10.1016/j.yexcr.2016.06.005openalex-snapshot
Berberine attenuates high glucose-induced fibrosis by activating the G protein-coupled bile acid receptor TGR5 and repressing the S1P2/MAPK signaling pathway in glomerular mesangial cells
inferred← citeshttps://doi.org/10.1016/j.yexcr.2021.112713openalex-snapshot
Silencing of RSPO1 mitigates obesity-related renal fibrosis in mice by deactivating Wnt/β-catenin pathway
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2019.01.024openalex-snapshot
Multiple roles of KLF15 in the heart: Underlying mechanisms and therapeutic implications
inferred← citeshttps://doi.org/10.1016/j.ymthe.2023.08.014openalex-snapshot
AMPK activation coupling SENP1-Sirt3 axis protects against acute kidney injury
inferred← citeshttps://doi.org/10.1021/acs.jafc.5c03418openalex-snapshot
Oleanolic Acid Regulates Intestinal Cell Proliferation and Protein Synthesis Capacity in Piglets via the Bile Acid-TGR5/AMPK/mTOR Axis
inferred← citeshttps://doi.org/10.1021/acsptsci.4c00701openalex-snapshot
Targeting of a Bile Acid Receptor, Takeda G Protein Receptor 5 [TGR5], by a Novel First-in-Class Competitive Antagonist, SBI-364, Diminishes Hepatic and Renal Cystogenesis in Polycystic Liver and Kidney Disease
inferred← citeshttps://doi.org/10.1038/nrneph.2015.171openalex-snapshot
Protective role of TGR5 activation
inferred← citeshttps://doi.org/10.1038/nrneph.2016.75openalex-snapshot
Obesity-related glomerulopathy: clinical and pathologic characteristics and pathogenesis
inferred← citeshttps://doi.org/10.1038/s41392-022-01036-5openalex-snapshot
Signaling pathways of chronic kidney diseases, implications for therapeutics
inferred← citeshttps://doi.org/10.1038/s41392-024-01811-6openalex-snapshot
Bile acid metabolism and signaling in health and disease: molecular mechanisms and therapeutic targets
inferred← citeshttps://doi.org/10.1038/s41419-024-06833-0openalex-snapshot
Mitochondrial metabolic reprogramming in diabetic kidney disease
inferred← citeshttps://doi.org/10.1038/s41420-020-00347-2openalex-snapshot
TGR5 deficiency aggravates hepatic ischemic/reperfusion injury via inhibiting SIRT3/FOXO3/HIF-1ɑ pathway
inferred← citeshttps://doi.org/10.1038/s41467-022-33824-6openalex-snapshot
The gut microbe Bacteroides fragilis ameliorates renal fibrosis in mice
inferred← citeshttps://doi.org/10.1038/s41581-021-00488-2openalex-snapshot
Lipidomic approaches to dissect dysregulated lipid metabolism in kidney disease
inferred← citeshttps://doi.org/10.1038/s41581-024-00806-4openalex-snapshot
Sirtuins in kidney health and disease
inferred← citeshttps://doi.org/10.1038/s41598-020-65423-0openalex-snapshot
Manipulating Sirtuin 3 pathway ameliorates renal damage in experimental diabetes
inferred← citeshttps://doi.org/10.1038/s41598-021-90589-6openalex-snapshot
Olive leaf extract prevents obesity, cognitive decline, and depression and improves exercise capacity in mice
inferred← citeshttps://doi.org/10.1038/s41598-025-89601-0openalex-snapshot
Integrating bioinformatics and metabolomics to identify potential biomarkers of hypertensive nephropathy
inferred← citeshttps://doi.org/10.1051/bioconf/202515403011openalex-snapshot
Acute toxicity test and lethal dose (LD50) from a combination of sambiloto extracts (Andrographis paniculate) and catfish oil (Pangasius micronema Blkr.) in mice
inferred← citeshttps://doi.org/10.1074/jbc.c117.794982openalex-snapshot
A dual agonist of farnesoid X receptor (FXR) and the G protein–coupled receptor TGR5, INT-767, reverses age-related kidney disease in mice
inferred← citeshttps://doi.org/10.1074/jbc.m117.779520openalex-snapshot
SGLT2 Protein Expression Is Increased in Human Diabetic Nephropathy
inferred← citeshttps://doi.org/10.1074/jbc.ra119.011913openalex-snapshot
Bile acid sequestration reverses liver injury and prevents progression of nonalcoholic steatohepatitis in Western diet–fed mice
inferred← citeshttps://doi.org/10.1080/0886022x.2025.2526686openalex-snapshot
Assessment, molecular mechanisms and therapeutic targets for renal functional reserve
inferred← citeshttps://doi.org/10.1080/0886022x.2025.2543927openalex-snapshot
Sirtuin 3 in diabetic kidney disease: mechanisms and pharmacotherapy
inferred← citeshttps://doi.org/10.1080/13880209.2024.2351946openalex-snapshot
Traditional Chinese medicine improved diabetic kidney disease through targeting gut microbiota
inferred← citeshttps://doi.org/10.1080/14728222.2019.1626827openalex-snapshot
A preclinical overview of emerging therapeutic targets for glomerular diseases
inferred← citeshttps://doi.org/10.1080/19490976.2023.2290331openalex-snapshot
Targeting gut microbiota in aging-related cardiovascular dysfunction: focus on the mechanisms
inferred← citeshttps://doi.org/10.1089/ars.2016.6682openalex-snapshot
Mitochondrial Dynamics Is Linked to Longevity and Protects from End-Organ Injury: The Emerging Role of Sirtuin 3
inferred← citeshttps://doi.org/10.1089/met.2020.0141openalex-snapshot
Potential Therapeutic Targets of Obesity-Related Glomerulopathy
inferred← citeshttps://doi.org/10.1096/fj.202402534ropenalex-snapshot
Mechanism of TGR5 in Ferroptosis of the Renal Tubular Epithelial Cells in Diabetes Mellitus and the Effect of Notoginsenoside Ft1
inferred← citeshttps://doi.org/10.1097/hjh.0000000000003189openalex-snapshot
Renal Farnesoid X Receptor improves high fructose-induced salt-sensitive hypertension in mice by inhibiting DNM3 to promote nitro oxide production
inferred← citeshttps://doi.org/10.1097/mnh.0000000000000374openalex-snapshot
Bile acid receptors and the kidney
inferred← citeshttps://doi.org/10.1101/2022.05.11.22274945openalex-snapshot
UDCA and INT-777 suppress cardiac fibrosis triggered by IL-11 through involvement of TGR5
inferred← citeshttps://doi.org/10.1101/2025.04.28.651123openalex-snapshot
A Multi-Organ Murine Metabolomics Atlas Reveals Molecular Dysregulations in Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1101/755801openalex-snapshot
Estrogen-related receptor agonism reverses mitochondrial dysfunction and inflammation in the aging kidney
inferred← citeshttps://doi.org/10.1111/apha.13634openalex-snapshot
Podocyte apoptosis in diabetic nephropathy by BASP1 activation of the p53 pathway via WT1
inferred← citeshttps://doi.org/10.1111/apha.70163openalex-snapshot
Activation of TGR5 Alleviates Renal Fibrosis by Promoting NEDD4L ‐Mediated p‐Smad2/3 Ubiquitination
inferred← citeshttps://doi.org/10.1111/bph.14849openalex-snapshot
Dual inhibition of cannabinoid CB1 receptor and inducible NOS attenuates obesity‐induced chronic kidney disease
inferred← citeshttps://doi.org/10.1111/bph.70619openalex-snapshot
The bile acid receptor TGR5 promotes functional recovery after spinal cord injury by rescuing mitochondrial dysfunction and suppressing AIM2‐mediated pyroptosis
inferred← citeshttps://doi.org/10.1111/nep.70156openalex-snapshot
A Comprehensive Analysis of Serum and Urine Bile Acid Profiles in Chronic Kidney Disease: An Exploratory Study of Clinical Associations
inferred← citeshttps://doi.org/10.1111/sji.13361openalex-snapshot
The role of bile acid receptor TGR5 in regulating inflammatory signalling
inferred← citeshttps://doi.org/10.1126/scitranslmed.abn7491openalex-snapshot
A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis
inferred← citeshttps://doi.org/10.1126/scitranslmed.ado5177openalex-snapshot
Intestinal TGR5-targeted carrier-drug conjugate improves glycemic control in mice and pigs
inferred← citeshttps://doi.org/10.1152/ajpendo.00248.2024openalex-snapshot
Roux-en-Y gastric bypass alleviates kidney inflammation and improves kidney function in db/db mice by activating TLCA/TGR5 pathway
inferred← citeshttps://doi.org/10.1152/ajpheart.00027.2022openalex-snapshot
Bile acids and salt-sensitive hypertension: a role of the gut-liver axis
inferred← citeshttps://doi.org/10.1152/ajprenal.00110.2025openalex-snapshot
Role of nuclear receptors, lipid metabolism, and mitochondrial function in the pathogenesis of diabetic kidney disease
inferred← citeshttps://doi.org/10.1152/ajprenal.00189.2023openalex-snapshot
Mitochondrial dysfunction in the pathophysiology of renal diseases
inferred← citeshttps://doi.org/10.1152/ajprenal.00614.2020openalex-snapshot
Sacubitril/valsartan treatment has differential effects in modulating diabetic kidney disease in db/db mice and KKAy mice compared with valsartan treatment
inferred← citeshttps://doi.org/10.1155/2019/6372786openalex-snapshot
Activation of TGR5 Partially Alleviates High Glucose-Induced Cardiomyocyte Injury by Inhibition of Inflammatory Responses and Oxidative Stress
inferred← citeshttps://doi.org/10.1159/000507117openalex-snapshot
Histone Deacetylases Take Center Stage on Regulation of Podocyte Function
inferred← citeshttps://doi.org/10.1159/000507784openalex-snapshot
Obesity-Related Glomerulopathy: A Latent Change in Obesity Requiring More Attention
inferred← citeshttps://doi.org/10.1159/000518132openalex-snapshot
The Updates of Podocyte Lipid Metabolism in Proteinuric Kidney Disease
inferred← citeshttps://doi.org/10.1159/000530485openalex-snapshot
From Physiology to Pathology: The Role of Mitochondria in Acute Kidney Injuries and Chronic Kidney Diseases
inferred← citeshttps://doi.org/10.11606/d.42.2020.tde-22012020-111755openalex-snapshot
Caracterização dos efeitos da dieta hiperlipídica nos rins de camundongos deficientes em adiponectina.
inferred← citeshttps://doi.org/10.1161/hypertensionaha.115.06417openalex-snapshot
Role of Bile Acid–Regulated Nuclear Receptor FXR and G Protein–Coupled Receptor TGR5 in Regulation of Cardiorenal Syndrome (Cardiovascular Disease and Chronic Kidney Disease)
inferred← citeshttps://doi.org/10.1167/iovs.65.1.14openalex-snapshot
UCP2–SIRT3 Signaling Relieved Hyperglycemia-Induced Oxidative Stress and Senescence in Diabetic Retinopathy
inferred← citeshttps://doi.org/10.1172/jci.insight.140483openalex-snapshot
Depletion of protein kinase STK25 ameliorates renal lipotoxicity and protects against diabetic kidney disease
inferred← citeshttps://doi.org/10.11817/j.issn.1672-7347.2021.210199openalex-snapshot
Research advance in the mechanism for oxidative stress-induced podocyte injury in diabetic kidney disease.
inferred← citeshttps://doi.org/10.1186/s12906-025-05177-2openalex-snapshot
QuYuShengXin formula reshapes bile-acid-mediated macrophage polarization in the treatment of ulcerative colitis
inferred← citeshttps://doi.org/10.1186/s12929-020-00656-9openalex-snapshot
Activation of TGR5 protects blood brain barrier via the BRCA1/Sirt1 pathway after middle cerebral artery occlusion in rats
inferred← citeshttps://doi.org/10.1186/s12937-024-00928-2openalex-snapshot
Circulating concentrations of bile acids and prevalent chronic kidney disease among newly diagnosed type 2 diabetes: a cross-sectional study
inferred← citeshttps://doi.org/10.1186/s12951-025-03190-8openalex-snapshot
Polyzwitterion-branched polycholic acid nanocarriers based oral delivery insulin for long-term glucose and metabolic regulation in diabetes mellitus
inferred← citeshttps://doi.org/10.1186/s12967-024-05922-0openalex-snapshot
Conjugated bile acids alleviate acute pancreatitis through inhibition of TGR5 and NLRP3 mediated inflammation
inferred← citeshttps://doi.org/10.1186/s13000-018-0700-5openalex-snapshot
TGR5 expression in normal kidney and renal neoplasms
inferred← citeshttps://doi.org/10.1186/s13020-026-01328-wopenalex-snapshot
Fatty acid metabolism: opportunities and challenges of traditional Chinese medicine in the treatment of renal fibrosis
inferred← citeshttps://doi.org/10.1210/endocr/bqab234openalex-snapshot
Podocyte Bioenergetics in the Development of Diabetic Nephropathy: The Role of Mitochondria
inferred← citeshttps://doi.org/10.1360/n052018-00154openalex-snapshot
Role of histone deacetylases in the pathogenesis of kidney diseases
inferred← citeshttps://doi.org/10.1515/mr-2024-0020openalex-snapshot
Dysregulated bile acid homeostasis: unveiling its role in metabolic diseases
inferred← citeshttps://doi.org/10.15212/bioi-2024-0137openalex-snapshot
Recent Developments in Diabetes Management: Exploring Receptors, Pathways, and Compounds
inferred← citeshttps://doi.org/10.15252/embr.201948781openalex-snapshot
Smad4 promotes diabetic nephropathy by modulating glycolysis and OXPHOS
inferred← citeshttps://doi.org/10.1681/asn.2016101123openalex-snapshot
Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy
inferred← citeshttps://doi.org/10.1681/asn.2017020222openalex-snapshot
FXR/TGR5 Dual Agonist Prevents Progression of Nephropathy in Diabetes and Obesity
inferred← citeshttps://doi.org/10.1681/asn.2017111218openalex-snapshot
Sirtuins in Renal Health and Disease
inferred← citeshttps://doi.org/10.1681/asn.2018030271openalex-snapshot
Bile Acid G Protein-Coupled Membrane Receptor TGR5 Modulates Aquaporin 2–Mediated Water Homeostasis
inferred← citeshttps://doi.org/10.18632/oncotarget.17165openalex-snapshot
SIRT3-KLF15 signaling ameliorates kidney injury induced by hypertension
inferred← citeshttps://doi.org/10.19080/crdoj.2018.09.555759openalex-snapshot
TGR5 as New Target in Diabetes Care
inferred← citeshttps://doi.org/10.21037/atm-21-2631openalex-snapshot
TGR5 protects against cholestatic liver disease via suppressing the NF-κB pathway and activating the Nrf2/HO-1 pathway
inferred← citeshttps://doi.org/10.21203/rs.3.rs-2789347/v1openalex-snapshot
Norcholic acid: a novel biomarker of early kidney injury in patients with metabolic dysfunction-associated fatty liver disease
inferred← citeshttps://doi.org/10.21203/rs.3.rs-36666/v1openalex-snapshot
INT-777 Improves Cognitive Impairment after Sepsis by Attenuating Neuroinflammation Through the TGR5/cAMP/PKA/CREB Signaling Axis in Rats
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3875238/v1openalex-snapshot
Anti-diabetic effect of di-caffeoylquinic acid is associated with the modulation of gut microbiota and bile acid metabolism
inferred← citeshttps://doi.org/10.2147/cia.s431220openalex-snapshot
Bile Acid Network and Vascular Calcification-Associated Diseases: Unraveling the Intricate Connections and Therapeutic Potential
inferred← citeshttps://doi.org/10.2147/dddt.s476815openalex-snapshot
New Perspectives on Obesity-Associated Nephropathy from Pathophysiology to Therapeutics: Revealing the Promise of GLP-1 RA Therapy
inferred← citeshttps://doi.org/10.2147/dddt.s530823openalex-snapshot
DHLCA Alleviates Diabetic Kidney Disease via TGR5/FXR Activation and Gut Microbiota Remodeling
inferred← citeshttps://doi.org/10.2147/dmso.s334199openalex-snapshot
Obesity-Related Glomerulopathy: From Mechanism to Therapeutic Target
inferred← citeshttps://doi.org/10.22038/ijbms.2017.8842openalex-snapshot
Mori cortex prevents kidney damage through inhibiting expression of inflammatory factors in the glomerulus in streptozocin-induced diabetic rats.
inferred← citeshttps://doi.org/10.2218/gtopdb/f8/2019.4openalex-snapshot
Bile acid receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
inferred← citeshttps://doi.org/10.2218/gtopdb/f8/2023.1openalex-snapshot
Bile acid receptor in GtoPdb v.2023.1
inferred← citeshttps://doi.org/10.23876/j.krcp.22.233openalex-snapshot
Mitochondrial quality control and its emerging role in the pathogenesis of diabetic kidney disease
inferred← citeshttps://doi.org/10.2478/dine-2021-0005openalex-snapshot
Key profibrotic and pro-inflammatory pathways in the pathogenesis of diabetic kidney disease
inferred← citeshttps://doi.org/10.3350/cmh.2024.0782openalex-snapshot
Bioactive metabolites: A clue to the link between MASLD and CKD?
inferred← citeshttps://doi.org/10.3389/fcell.2022.832887openalex-snapshot
Podocyte Injury in Diabetic Kidney Disease: A Focus on Mitochondrial Dysfunction
inferred← citeshttps://doi.org/10.3389/fcvm.2024.1430772openalex-snapshot
Protective effect of UDCA against IL-11- induced cardiac fibrosis is mediated by TGR5 signalling
inferred← citeshttps://doi.org/10.3389/fendo.2021.636175openalex-snapshot
Roles of Gut Microbial Metabolites in Diabetic Kidney Disease
inferred← citeshttps://doi.org/10.3389/fendo.2022.1026995openalex-snapshot
Lower bile acids as an independent risk factor for renal outcomes in patients with type 2 diabetes mellitus and biopsy-proven diabetic kidney disease
inferred← citeshttps://doi.org/10.3389/fendo.2022.801303openalex-snapshot
SIRT1–SIRT7 in Diabetic Kidney Disease: Biological Functions and Molecular Mechanisms
inferred← citeshttps://doi.org/10.3389/fendo.2023.1112363openalex-snapshot
The impact of oxidative stress-induced mitochondrial dysfunction on diabetic microvascular complications
inferred← citeshttps://doi.org/10.3389/fendo.2024.1336402openalex-snapshot
Lipid metabolism disorder in diabetic kidney disease
inferred← citeshttps://doi.org/10.3389/fendo.2024.1441415openalex-snapshot
Intestinal flora and bile acid interactions impact the progression of diabetic kidney disease
inferred← citeshttps://doi.org/10.3389/fendo.2024.1524674openalex-snapshot
Sirtuins in kidney homeostasis and disease: where are we now?
inferred← citeshttps://doi.org/10.3389/fendo.2025.1676017openalex-snapshot
Dysregulated bile acid metabolism as a novel player in gout progression: emerging therapeutic strategies
inferred← citeshttps://doi.org/10.3389/fimmu.2018.01853openalex-snapshot
Bile Acids Activated Receptors Regulate Innate Immunity
inferred← citeshttps://doi.org/10.3389/fmars.2022.861117openalex-snapshot
Bile Acids Reduced the Lipid Deposition in Fatty Degenerated Hepatocytes of Pearl Gentian Grouper (Epinephelus fuscoguttatus♂ × Epinephelus lanceolatus♀) in vitro
inferred← citeshttps://doi.org/10.3389/fmicb.2022.977187openalex-snapshot
The role and mechanisms of gut microbiota in diabetic nephropathy, diabetic retinopathy and cardiovascular diseases
inferred← citeshttps://doi.org/10.3389/fmicb.2023.1207132openalex-snapshot
The roles of gut microbiota and its metabolites in diabetic nephropathy
inferred← citeshttps://doi.org/10.3389/fmicb.2024.1458090openalex-snapshot
Fecal bile acid dysmetabolism and reduced ursodeoxycholic acid correlate with novel microbial signatures in feline chronic kidney disease
inferred← citeshttps://doi.org/10.3389/fmicb.2025.1729409openalex-snapshot
Clinical efficacy of probiotics in the treatment of diabetes kidney disease: a systematic review and meta-analysis
inferred← citeshttps://doi.org/10.3389/fmicb.2026.1979411openalex-snapshot
Gut microbiota-derived small molecules, peptides, and proteins in GPCR signaling: current evidence for β-arrestin involvement
inferred← citeshttps://doi.org/10.3389/fnut.2026.1778473openalex-snapshot
Gut microbiota-liver-kidney axis in diabetic kidney disease: mechanistic insights into amino acid metabolism and nutritional intervention strategies targeting natural bioactive compounds
inferred← citeshttps://doi.org/10.3389/fphar.2017.00468openalex-snapshot
Allspice and Clove As Source of Triterpene Acids Activating the G Protein-Coupled Bile Acid Receptor TGR5
inferred← citeshttps://doi.org/10.3389/fphar.2020.586892openalex-snapshot
Diabetic Nephropathy: Novel Molecular Mechanisms and Therapeutic Targets
inferred← citeshttps://doi.org/10.3389/fphar.2021.637051openalex-snapshot
Amelioration of Endothelial Dysfunction in Diabetes: Role of Takeda G Protein–Coupled Receptor 5
inferred← citeshttps://doi.org/10.3389/fphys.2016.00646openalex-snapshot
TGR5, Not Only a Metabolic Regulator
inferred← citeshttps://doi.org/10.3389/fphys.2023.1176894openalex-snapshot
Bibliometric visualization analysis of gut-kidney axis from 2003 to 2022
inferred← citeshttps://doi.org/10.3389/fphys.2023.1322288openalex-snapshot
Bile acid receptors and renal regulation of water homeostasis
inferred← citeshttps://doi.org/10.3389/fphys.2026.1747341openalex-snapshot
The role of bile acid-activated receptor TGR5 in inflammation and liver diseases
inferred← citeshttps://doi.org/10.3390/antiox11091706openalex-snapshot
Bile Acids Induce Alterations in Mitochondrial Function in Skeletal Muscle Fibers
inferred← citeshttps://doi.org/10.3390/antiox12010094openalex-snapshot
Mechanisms Underlying Neurodegenerative Disorders and Potential Neuroprotective Activity of Agrifood By-Products
inferred← citeshttps://doi.org/10.3390/biomedicines10092066openalex-snapshot
Beneficial Effects of Empagliflozin Are Mediated by Reduced Renal Inflammation and Oxidative Stress in Spontaneously Hypertensive Rats Expressing Human C-Reactive Protein
inferred← citeshttps://doi.org/10.3390/cells10112945openalex-snapshot
Mitochondria in Diabetic Kidney Disease
inferred← citeshttps://doi.org/10.3390/cells11203236openalex-snapshot
The Contribution of Lipotoxicity to Diabetic Kidney Disease
inferred← citeshttps://doi.org/10.3390/ijms20246280openalex-snapshot
Effects of Farnesiferol B on Ischemia-Reperfusion-Induced Renal Damage, Inflammation, and NF-κB Signaling
inferred← citeshttps://doi.org/10.3390/ijms24032408openalex-snapshot
Role of FXR in Renal Physiology and Kidney Diseases
inferred← citeshttps://doi.org/10.3390/molecules29122747openalex-snapshot
Modulating the Gut Microbiota and Metabolites with Traditional Chinese Medicines: An Emerging Therapy for Type 2 Diabetes Mellitus and Its Complications
inferred← citeshttps://doi.org/10.3390/nu11040722openalex-snapshot
Lipid Accumulation and Chronic Kidney Disease
inferred← citeshttps://doi.org/10.3390/ph14050435openalex-snapshot
Targeting Energy Expenditure—Drugs for Obesity Treatment
inferred← citeshttps://doi.org/10.3390/ph16091256openalex-snapshot
Targeting Renal Proximal Tubule Cells in Obesity-Related Glomerulopathy
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