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Evidence for a Mitochondrial Regulatory Pathway Defined by Peroxisome Proliferator–Activated Receptor-γ Coactivator-1α, Estrogen-Related Receptor-α, and Mitofusin 2
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1006/bbrc.1999.1145openalex-snapshot
Role of the β3-Adrenergic Receptor and/or a Putative β4-Adrenergic Receptor on the Expression of Uncoupling Proteins and Peroxisome Proliferator-Activated Receptor-γ Coactivator-1
inferredcites →https://doi.org/10.1006/jmbi.2001.5091openalex-snapshot
A novel functional co-operation between MyoD, MEF2 and TRα1 is sufficient for the induction of GLUT4 gene transcription
inferredcites →https://doi.org/10.1007/s00125-005-1918-9openalex-snapshot
Could the low level of expression of the gene encoding skeletal muscle mitofusin-2 account for the metabolic inflexibility of obesity?
inferredcites →https://doi.org/10.1016/j.cell.2004.09.013openalex-snapshot
Defects in Adaptive Energy Metabolism with CNS-Linked Hyperactivity in PGC-1α Null Mice
inferredcites →https://doi.org/10.1016/s0092-8674(00)80611-xopenalex-snapshot
Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1
inferredcites →https://doi.org/10.1016/s0092-8674(00)81410-5openalex-snapshot
A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis
inferredcites →https://doi.org/10.1016/s0303-7207(01)00451-8openalex-snapshot
Rapid in vivo PGC-1 mRNA upregulation in brown adipose tissue of Wistar rats by a β3-adrenergic agonist and lack of effect of leptin
inferredcites →https://doi.org/10.1016/s1043-2760(01)00457-xopenalex-snapshot
PGC-1, a versatile coactivator
inferredcites →https://doi.org/10.1016/s1534-5807(03)00170-9openalex-snapshot
Suppression of β Cell Energy Metabolism and Insulin Release by PGC-1α
inferredcites →https://doi.org/10.1038/35093050openalex-snapshot
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
inferredcites →https://doi.org/10.1038/35093131openalex-snapshot
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
inferredcites →https://doi.org/10.1038/nature00904openalex-snapshot
Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres
inferredcites →https://doi.org/10.1038/nature01667openalex-snapshot
Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction
inferredcites →https://doi.org/10.1038/nature03354openalex-snapshot
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
inferredcites →https://doi.org/10.1038/ncb1161openalex-snapshot
Dysregulation of HSG triggers vascular proliferative disorders
inferredcites →https://doi.org/10.1038/sj.emboj.7600351openalex-snapshot
Activation of cardiac Cdk9 represses PGC‐1 and confers a predisposition to heart failure
inferredcites →https://doi.org/10.1073/pnas.0308686101openalex-snapshot
The estrogen-related receptor α (ERRα) functions in PPARγ coactivator 1α (PGC-1α)-induced mitochondrial biogenesis
inferredcites →https://doi.org/10.1073/pnas.0401401101openalex-snapshot
Errα and Gabpa/b specify PGC-1α-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle
inferredcites →https://doi.org/10.1073/pnas.0401420101openalex-snapshot
Regulation of PPARγ coactivator 1α (PGC-1α) signaling by an estrogen-related receptor α (ERRα) ligand
inferredcites →https://doi.org/10.1073/pnas.061035098openalex-snapshot
Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1
inferredcites →https://doi.org/10.1073/pnas.1032913100openalex-snapshot
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
inferredcites →https://doi.org/10.1074/jbc.273.1.5openalex-snapshot
Uncoupling Protein-3 Expression in Rodent Skeletal Muscle Is Modulated by Food Intake but Not by Changes in Environmental Temperature
inferredcites →https://doi.org/10.1074/jbc.m201134200openalex-snapshot
The PGC-1-related Protein PERC Is a Selective Coactivator of Estrogen Receptor α
inferredcites →https://doi.org/10.1074/jbc.m212754200openalex-snapshot
Mitofusin-2 Determines Mitochondrial Network Architecture and Mitochondrial Metabolism
inferredcites →https://doi.org/10.1074/jbc.m212923200openalex-snapshot
The Transcriptional Coactivator PGC-1 Regulates the Expression and Activity of the Orphan Nuclear Receptor Estrogen-Related Receptor α (ERRα)
inferredcites →https://doi.org/10.1074/jbc.m301850200openalex-snapshot
Bioenergetic Analysis of Peroxisome Proliferator-activated Receptor γ Coactivators 1α and 1β (PGC-1α and PGC-1β) in Muscle Cells
inferredcites →https://doi.org/10.1074/jbc.m306609200openalex-snapshot
Differential Regulation of the Muscle-specific GLUT4 Enhancer in Regenerating and Adult Skeletal Muscle
inferredcites →https://doi.org/10.1074/jbc.m313543200openalex-snapshot
A Polymorphic Autoregulatory Hormone Response Element in the Human Estrogen-related Receptor α (ERRα) Promoter Dictates Peroxisome Proliferator-activated Receptor γ Coactivator-1α Control of ERRα Expression
inferredcites →https://doi.org/10.1083/jcb.200211046openalex-snapshot
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
inferredcites →https://doi.org/10.1084/jem.20021842openalex-snapshot
Orphan Nuclear Receptor Nur77 Is Involved in Caspase-independent Macrophage Cell Death
inferredcites →https://doi.org/10.1093/hmg/ddi149openalex-snapshot
The Charcot–Marie–Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system
inferredcites →https://doi.org/10.1113/jphysiol.2005.092031openalex-snapshot
Mitofusins 1/2 and ERRα expression are increased in human skeletal muscle after physical exercise
inferredcites →https://doi.org/10.1128/mcb.17.9.5400openalex-snapshot
The Orphan Nuclear Receptor Estrogen-Related Receptor α Is a Transcriptional Regulator of the Human Medium-Chain Acyl Coenzyme A Dehydrogenase Gene
inferredcites →https://doi.org/10.1172/jci10268openalex-snapshot
Peroxisome proliferator–activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis
inferredcites →https://doi.org/10.1210/er.2002-0012openalex-snapshot
Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α (PGC-1α): Transcriptional Coactivator and Metabolic Regulator
inferredcites →https://doi.org/10.1242/jcs.00479openalex-snapshot
Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells
inferredcites →https://doi.org/10.1242/jcs.114.5.867openalex-snapshot
Control of mitochondrial morphology by a human mitofusin
inferredcites →https://doi.org/10.1242/jcs.115.8.1663openalex-snapshot
Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo
inferredcites →https://doi.org/10.2337/diabetes.54.9.2685openalex-snapshot
Expression of Mfn2, the Charcot-Marie-Tooth Neuropathy Type 2A Gene, in Human Skeletal Muscle
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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eIF2α Phosphorylation-Mediated Transcriptional Reprogramming Suppresses Impairment of Mitochondrial and GSH Homeostasis and Thereby Ferroptosis During ER Stress
inferred← citeshttps://doi.org/10.1002/advs.202405153openalex-snapshot
RBBP6‐Mediated ERRα Degradation Contributes to Mitochondrial Injury in Renal Tubular Cells in Diabetic Kidney Disease
inferred← citeshttps://doi.org/10.1002/ana.21086openalex-snapshot
Mitochondrial coupling defect in Charcot–Marie–Tooth type 2A disease
inferred← citeshttps://doi.org/10.1002/cbf.1773openalex-snapshot
Key regulators of mitochondrial biogenesis are increased in kidneys of growth hormone receptor knockout (GHRKO) mice
inferred← citeshttps://doi.org/10.1002/cmdc.202400298openalex-snapshot
In Silico Prediction of ERRα Agonists Based on Combined Features and Stacking Ensemble Method
inferred← citeshttps://doi.org/10.1002/emmm.201303782openalex-snapshot
Mitochondrial response to nutrient availability and its role in metabolic disease
inferred← citeshttps://doi.org/10.1002/jcb.27995openalex-snapshot
Epigallocatechin‐3‐gallate regulates mitofusin 2 expression through the peroxisome proliferator‐activated receptor‐γ coactivator‐1α and estrogen‐related receptor‐α pathway
inferred← citeshttps://doi.org/10.1002/jcp.23021openalex-snapshot
Crosstalk between mitochondrial (dys)function and mitochondrial abundance
inferred← citeshttps://doi.org/10.1002/jcp.25109openalex-snapshot
Leptin Effect on Acetylation and Phosphorylation of Pgc1α in Muscle Cells Associated With Ampk and Akt Activation in High‐Glucose Medium
inferred← citeshttps://doi.org/10.1002/jcp.30084openalex-snapshot
Molecular pathophysiology of acute kidney injury: The role of sirtuins and their interactions with other macromolecular players
inferred← citeshttps://doi.org/10.1002/jcsm.12178openalex-snapshot
Mitochondria and ageing: role in heart, skeletal muscle and adipose tissue
inferred← citeshttps://doi.org/10.1002/oby.24132openalex-snapshot
Differential mitochondrial adaptation and FNDC5 production in brown and white adipose tissue in response to cold and obesity
inferred← citeshttps://doi.org/10.1007/164_2016_38openalex-snapshot
Mitochondrial Fission in Human Diseases
inferred← citeshttps://doi.org/10.1007/978-1-4614-3573-0_2openalex-snapshot
Mitochondrial Dynamics: The Intersection of Form and Function
inferred← citeshttps://doi.org/10.1007/978-1-4614-4599-9_13openalex-snapshot
Mitochondria in the Aging Heart
inferred← citeshttps://doi.org/10.1007/978-1-4614-4599-9_22openalex-snapshot
Thyroid Hormone and Myocardial Mitochondria
inferred← citeshttps://doi.org/10.1007/978-1-4939-1227-8_6openalex-snapshot
Transcriptional Control of Mitochondrial Biogenesis and Maturation
inferred← citeshttps://doi.org/10.1007/978-3-031-88361-3_2openalex-snapshot
Mitochondrial Biogenesis in Skeletal Muscle
inferred← citeshttps://doi.org/10.1007/978-3-319-01008-3_6openalex-snapshot
The Skeletal Muscle in Metabolic Syndrome
inferred← citeshttps://doi.org/10.1007/978-3-319-73344-9_18openalex-snapshot
Targeting Mitochondria with Sweat: Improving Mitochondrial Function with Physical Activity
inferred← citeshttps://doi.org/10.1007/978-3-319-73344-9_3openalex-snapshot
Mitochondrial Dynamics: A Journey from Mitochondrial Morphology to Mitochondrial Function and Quality
inferred← citeshttps://doi.org/10.1007/978-3-642-30018-9_195openalex-snapshot
Role of Antioxidant Signaling in Mitochondrial Adaptation to Muscle Contraction
inferred← citeshttps://doi.org/10.1007/s00109-010-0662-xopenalex-snapshot
Mitochondria as integrators of signal transduction and energy production in cardiac physiology and disease
inferred← citeshttps://doi.org/10.1007/s00109-015-1263-5openalex-snapshot
Mitochondrial dynamics in pulmonary arterial hypertension
inferred← citeshttps://doi.org/10.1007/s00109-019-01796-8openalex-snapshot
Skeletal muscle miR-34a/SIRT1:AMPK axis is activated in experimental and human non-alcoholic steatohepatitis
inferred← citeshttps://doi.org/10.1007/s00125-009-1403-yopenalex-snapshot
Genes involved in mitochondrial biogenesis/function are induced in response to bilio-pancreatic diversion in morbidly obese individuals with normal glucose tolerance but not in type 2 diabetic patients
inferred← citeshttps://doi.org/10.1007/s10522-018-9768-2openalex-snapshot
Mitochondrial dysfunction in metabolism and ageing: shared mechanisms and outcomes?
inferred← citeshttps://doi.org/10.1007/s10557-012-6425-xopenalex-snapshot
Chronic Metformin Associated Cardioprotection Against Infarction: Not Just a Glucose Lowering Phenomenon
inferred← citeshttps://doi.org/10.1007/s10741-017-9623-6openalex-snapshot
A comprehensive review of the bioenergetics of fatty acid and glucose metabolism in the healthy and failing heart in nondiabetic condition
inferred← citeshttps://doi.org/10.1007/s10863-011-9332-0openalex-snapshot
The complex interplay between mitochondrial dynamics and cardiac metabolism
inferred← citeshttps://doi.org/10.1007/s11010-022-04380-wopenalex-snapshot
Estrogen-related receptor alpha in select host functions and cancer: new frontiers
inferred← citeshttps://doi.org/10.1007/s11033-014-3698-0openalex-snapshot
New gene targets of PGC-1α and ERRα co-regulation in C2C12 myotubes
inferred← citeshttps://doi.org/10.1007/s11064-015-1606-1openalex-snapshot
The Neuroprotective Effect of Tetramethylpyrazine Against Contusive Spinal Cord Injury by Activating PGC-1α in Rats
inferred← citeshttps://doi.org/10.1007/s11325-025-03504-yopenalex-snapshot
PGC-1α: a potential therapeutic target for upper airway dilator muscle structure and dysfunction in OSA
inferred← citeshttps://doi.org/10.1007/s11684-023-1036-4openalex-snapshot
lncRNA ZNF593-AS inhibits cardiac hypertrophy and myocardial remodeling by upregulating Mfn2 expression
inferred← citeshttps://doi.org/10.1007/s12011-021-02766-3openalex-snapshot
Harmful Effects of Inorganic Mercury Exposure on Kidney Cells: Mitochondrial Dynamics Disorder and Excessive Oxidative Stress
inferred← citeshttps://doi.org/10.1007/s12035-015-9299-7openalex-snapshot
Overexpression of PGC-1α Influences Mitochondrial Signal Transduction of Dopaminergic Neurons
inferred← citeshttps://doi.org/10.1007/s12035-018-1342-zopenalex-snapshot
Amyloid β Peptide Compromises Neural Stem Cell Fate by Irreversibly Disturbing Mitochondrial Oxidative State and Blocking Mitochondrial Biogenesis and Dynamics
inferred← citeshttps://doi.org/10.1007/s12035-025-05146-3openalex-snapshot
PGC-1α Expands Neural Precursor Pool and Facilitates Cognitive Recovery Within AD Hippocampus Through the Regulation of Mitochondrial Dynamics
inferred← citeshttps://doi.org/10.1007/s12640-021-00460-9openalex-snapshot
Liraglutide Regulates Mitochondrial Quality Control System Through PGC-1α in a Mouse Model of Parkinson’s Disease
inferred← citeshttps://doi.org/10.1007/s13105-011-0083-5openalex-snapshot
Expression of nuclear-encoded genes involved in mitochondrial biogenesis and dynamics in experimentally denervated muscle
inferred← citeshttps://doi.org/10.1016/b978-0-12-811752-1.00003-1openalex-snapshot
Overview of the Cross-Talk Between Hormones and Mitochondria
inferred← citeshttps://doi.org/10.1016/b978-0-443-18858-9.00003-2openalex-snapshot
Mitochondrial dynamics and mitochondrial biogenesis
inferred← citeshttps://doi.org/10.1016/bs.apcsb.2018.11.009openalex-snapshot
Relationship between mitofusin 2 and cancer
inferred← citeshttps://doi.org/10.1016/j.anireprosci.2024.107664openalex-snapshot
Role of MFN2 in bovine embryonic development and the mitigation of ER stress
inferred← citeshttps://doi.org/10.1016/j.aquatox.2025.107327openalex-snapshot
Oxidative stress and mitochondrial dysfunctions induced by cyanobacterial microcystin-LR in primary grass carp hepatocytes
inferred← citeshttps://doi.org/10.1016/j.arr.2020.101025openalex-snapshot
The emerging role of skeletal muscle mitochondrial dynamics in exercise and ageing
inferred← citeshttps://doi.org/10.1016/j.arr.2025.102957openalex-snapshot
Serotonin-mediated regulation of mitophagy in Alzheimer's disease: Mechanistic insights and therapeutic potential
inferred← citeshttps://doi.org/10.1016/j.bbabio.2010.02.017openalex-snapshot
Alterations in the mitochondrial regulatory pathways constituted by the nuclear co-factors PGC-1α or PGC-1β and mitofusin 2 in skeletal muscle in type 2 diabetes
inferred← citeshttps://doi.org/10.1016/j.bbabio.2010.02.030openalex-snapshot
Multi-site control and regulation of mitochondrial energy production
inferred← citeshttps://doi.org/10.1016/j.bbadis.2010.12.009openalex-snapshot
Functional and physiological genomics of estrogen-related receptors (ERRs) in health and disease
inferred← citeshttps://doi.org/10.1016/j.bbadis.2018.05.018openalex-snapshot
MitoQ protects dopaminergic neurons in a 6-OHDA induced PD model by enhancing Mfn2-dependent mitochondrial fusion via activation of PGC-1α
inferred← citeshttps://doi.org/10.1016/j.bbadis.2023.166841openalex-snapshot
Bezafibrate confers neuroprotection in the 5xFAD mouse model of Alzheimer's disease
inferred← citeshttps://doi.org/10.1016/j.bbagen.2009.08.007openalex-snapshot
Response of mitochondrial fusion and fission protein gene expression to exercise in rat skeletal muscle
inferred← citeshttps://doi.org/10.1016/j.bbagen.2013.11.016openalex-snapshot
Skeletal muscle mitochondria: A major player in exercise, health and disease
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2010.09.006openalex-snapshot
Bioenergetics of the failing heart
inferred← citeshttps://doi.org/10.1016/j.bbr.2016.07.021openalex-snapshot
Lack of age-related clinical progression in PGC-1α-deficient mice – implications for mitochondrial encephalopathies
inferred← citeshttps://doi.org/10.1016/j.bbrc.2007.08.191openalex-snapshot
Overexpression of Mitofusin 2 inhibited oxidized low-density lipoprotein induced vascular smooth muscle cell proliferation and reduced atherosclerotic lesion formation in rabbit
inferred← citeshttps://doi.org/10.1016/j.bbrc.2010.08.108openalex-snapshot
Mitofusin-2 is a novel direct target of p53
inferred← citeshttps://doi.org/10.1016/j.bbrc.2018.03.080openalex-snapshot
Estrogen-related receptor α is essential for maintaining mitochondrial integrity in cisplatin-induced acute kidney injury
inferred← citeshttps://doi.org/10.1016/j.beem.2012.06.002openalex-snapshot
Mitochondria and endocrine function of adipose tissue
inferred← citeshttps://doi.org/10.1016/j.biocel.2009.02.004openalex-snapshot
Role of mitochondrial dynamics proteins in the pathophysiology of obesity and type 2 diabetes
inferred← citeshttps://doi.org/10.1016/j.biocel.2021.105951openalex-snapshot
The relevance of mitochondrial morphology for human disease
inferred← citeshttps://doi.org/10.1016/j.brainres.2016.09.047openalex-snapshot
MiR-195 dependent roles of mitofusin2 in the mitochondrial dysfunction of hippocampal neurons in SAMP8 mice
inferred← citeshttps://doi.org/10.1016/j.cbi.2017.05.003openalex-snapshot
Early energy metabolism-related molecular events in skeletal muscle of diabetic rats: The effects of l-arginine and SOD mimic
inferred← citeshttps://doi.org/10.1016/j.cellsig.2011.07.013openalex-snapshot
Recent progress toward understanding the molecular mechanisms that regulate skeletal muscle mass
inferred← citeshttps://doi.org/10.1016/j.cellsig.2020.109714openalex-snapshot
Activation of TNFR1 and TLR4 following oxygen glucose deprivation promotes mitochondrial fission in C6 astroglial cells
inferred← citeshttps://doi.org/10.1016/j.celrep.2020.108079openalex-snapshot
Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity
inferred← citeshttps://doi.org/10.1016/j.chembiol.2017.12.001openalex-snapshot
Identification of New Activators of Mitochondrial Fusion Reveals a Link between Mitochondrial Morphology and Pyrimidine Metabolism
inferred← citeshttps://doi.org/10.1016/j.cmet.2010.11.008openalex-snapshot
Total Skeletal Muscle PGC-1 Deficiency Uncouples Mitochondrial Derangements from Fiber Type Determination and Insulin Sensitivity
inferred← citeshttps://doi.org/10.1016/j.cmet.2012.10.005openalex-snapshot
RETRACTED: The Ubiquitin Ligase Mul1 Induces Mitophagy in Skeletal Muscle in Response to Muscle-Wasting Stimuli
inferred← citeshttps://doi.org/10.1016/j.cmet.2013.03.002openalex-snapshot
Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure
inferred← citeshttps://doi.org/10.1016/j.cmet.2020.11.011openalex-snapshot
The Nuclear Receptor ESRRA Protects from Kidney Disease by Coupling Metabolism and Differentiation
inferred← citeshttps://doi.org/10.1016/j.cophys.2018.02.006openalex-snapshot
Mitochondrial dynamics and metabolic homeostasis
inferred← citeshttps://doi.org/10.1016/j.ejphar.2017.02.015openalex-snapshot
Effects of iron overload, an iron chelator and a T-Type calcium channel blocker on cardiac mitochondrial biogenesis and mitochondrial dynamics in thalassemic mice
inferred← citeshttps://doi.org/10.1016/j.envpol.2020.114855openalex-snapshot
Hexavalent chromium induces mitochondrial dynamics disorder in rat liver by inhibiting AMPK/PGC-1α signaling pathway
inferred← citeshttps://doi.org/10.1016/j.exger.2024.112514openalex-snapshot
The potential benefits of PGC-1α in treating Alzheimer's disease are dependent on the integrity of the LLKYL L3 motif: Effect of regulating mitochondrial axonal transportation
inferred← citeshttps://doi.org/10.1016/j.fct.2025.115335openalex-snapshot
Salidroside alleviates doxorubicin-induced hepatotoxicity via Sestrin2/AMPK-mediated pyroptotic inhibition
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2016.04.019openalex-snapshot
Altered mitochondrial dynamics and response to insulin in cybrid cells harboring a diabetes-susceptible mitochondrial DNA haplogroup
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2020.03.031openalex-snapshot
Oroxylin a promotes PGC-1α/Mfn2 signaling to attenuate hepatocyte pyroptosis via blocking mitochondrial ROS in alcoholic liver disease
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2025.07.025openalex-snapshot
MITF promotes MFN2-dependent mitochondrial fusion to protect retinal pigment epithelial cells from mitochondrial damage
inferred← citeshttps://doi.org/10.1016/j.hazadv.2022.100113openalex-snapshot
Recent developments in essentiality of trivalent chromium and toxicity of hexavalent chromium: Implications on human health and remediation strategies
inferred← citeshttps://doi.org/10.1016/j.ijcard.2018.05.046openalex-snapshot
Role of oxidative stress in the process of vascular remodeling following coronary revascularization
inferred← citeshttps://doi.org/10.1016/j.imr.2014.08.006openalex-snapshot
WITHDRAWN: Relationship between the regulation of muscle atrophy and mitochondrial turnover during chronic disuse
inferred← citeshttps://doi.org/10.1016/j.imr.2014.09.001openalex-snapshot
Recent advances in mitochondrial turnover during chronic muscle disuse
inferred← citeshttps://doi.org/10.1016/j.isci.2022.105480openalex-snapshot
PGC-1α in the myofibers regulates the balance between myogenic and adipogenic progenitors affecting muscle regeneration
inferred← citeshttps://doi.org/10.1016/j.jep.2021.114562openalex-snapshot
Danggui-Shaoyao-San improves cognitive impairment through inhibiting O-GlcNAc-modification of estrogen α receptor in female db/db mice
inferred← citeshttps://doi.org/10.1016/j.jff.2021.104757openalex-snapshot
Gum Arabic supplementation prevents loss of learning and memory through stimulation of mitochondrial function in the hippocampus of type 2 diabetic rats
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2017.11.012openalex-snapshot
Attenuation of obesity and insulin resistance by fish oil supplementation is associated with improved skeletal muscle mitochondrial function in mice fed a high-fat diet
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2023.109279openalex-snapshot
miR-494-5p mediates the antioxidant activity of EPA by targeting the mitochondrial elongation factor 1 gene MIEF1 in HepG2 cells
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2023.109532openalex-snapshot
Fuzhuan brick tea extract ameliorates obesity-induced skeletal muscle atrophy by alleviating mitochondrial dysfunction in mice
inferred← citeshttps://doi.org/10.1016/j.jsbmb.2012.01.012openalex-snapshot
Estrogen and the regulation of mitochondrial structure and function in the brain
inferred← citeshttps://doi.org/10.1016/j.jsbmb.2019.105413openalex-snapshot
Angiotensin II stimulation promotes mitochondrial fusion as a novel mechanism involved in protein kinase compartmentalization and cholesterol transport in human adrenocortical cells
inferred← citeshttps://doi.org/10.1016/j.jshs.2013.03.006openalex-snapshot
Mitochondrial redox metabolism in aging: Effect of exercise interventions
inferred← citeshttps://doi.org/10.1016/j.jtherbio.2017.04.008openalex-snapshot
Local muscle cooling does not impact expression of mitochondrial-related genes
inferred← citeshttps://doi.org/10.1016/j.kint.2020.09.037openalex-snapshot
Targeting energy pathways in kidney disease: the roles of sirtuins, AMPK, and PGC1α
inferred← citeshttps://doi.org/10.1016/j.kint.2022.01.030openalex-snapshot
Conditional deletion of myeloid-specific mitofusin 2 but not mitofusin 1 promotes kidney fibrosis
inferred← citeshttps://doi.org/10.1016/j.lfs.2007.04.003openalex-snapshot
Down-regulation of mitofusin-2 expression in cardiac hypertrophy in vitro and in vivo
inferred← citeshttps://doi.org/10.1016/j.lfs.2020.117762openalex-snapshot
TLR4 knockout upregulates the expression of Mfn2 and PGC-1α in a high-fat diet and ischemia-reperfusion mice model of liver injury
inferred← citeshttps://doi.org/10.1016/j.mad.2016.12.005openalex-snapshot
Mitochondrial activity and dynamics changes regarding metabolism in ageing and obesity
inferred← citeshttps://doi.org/10.1016/j.mad.2020.111345openalex-snapshot
Mitochondrial biogenesis in organismal senescence and neurodegeneration
inferred← citeshttps://doi.org/10.1016/j.mce.2013.08.004openalex-snapshot
MicroRNA-106b induces mitochondrial dysfunction and insulin resistance in C2C12 myotubes by targeting mitofusin-2
inferred← citeshttps://doi.org/10.1016/j.mehy.2015.10.004openalex-snapshot
Mitochondrial emitted electromagnetic signals mediate retrograde signaling
inferred← citeshttps://doi.org/10.1016/j.metabol.2014.01.006openalex-snapshot
The many roles of PGC-1α in muscle — recent developments
inferred← citeshttps://doi.org/10.1016/j.mito.2010.12.013openalex-snapshot
Dynamic regulation of mitochondrial function in preimplantation embryos and embryonic stem cells
inferred← citeshttps://doi.org/10.1016/j.mito.2011.03.121openalex-snapshot
Estrogen related receptors (ERRs): A new dawn in transcriptional control of mitochondrial gene networks
inferred← citeshttps://doi.org/10.1016/j.mito.2021.09.003openalex-snapshot
Mitofusin 2: A link between mitochondrial function and substrate metabolism?
inferred← citeshttps://doi.org/10.1016/j.mito.2023.02.001openalex-snapshot
Mitofusin-2: Functional switch between mitochondrial function and neurodegeneration
inferred← citeshttps://doi.org/10.1016/j.mito.2023.07.003openalex-snapshot
Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies
inferred← citeshttps://doi.org/10.1016/j.mocell.2024.100176openalex-snapshot
eIF2α phosphorylation-ATF4 axis-mediated transcriptional reprogramming mitigates mitochondrial impairment during ER stress
inferred← citeshttps://doi.org/10.1016/j.molcel.2016.02.022openalex-snapshot
Mitofusins, from Mitochondria to Metabolism
inferred← citeshttps://doi.org/10.1016/j.nbd.2012.07.004openalex-snapshot
Mutant SOD1G93A triggers mitochondrial fragmentation in spinal cord motor neurons: Neuroprotection by SIRT3 and PGC-1α
inferred← citeshttps://doi.org/10.1016/j.neulet.2008.04.104openalex-snapshot
Regulation of PGC-1α and PGC-1α-responsive genes with forskolin-induced Schwann cell differentiation
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2018.02.017openalex-snapshot
Nitric Oxide and Mitochondrial Function in Neurological Diseases
inferred← citeshttps://doi.org/10.1016/j.nut.2009.09.012openalex-snapshot
Acute and long-term nutrient-led modifications of gene expression: Potential role of SIRT1 as a central co-ordinator of short and longer-term programming of tissue function
inferred← citeshttps://doi.org/10.1016/j.phymed.2018.11.016openalex-snapshot
RETRACTED: Morphological control of mitochondria as the novel mechanism of Gastrodia elata in attenuating mutant huntingtin-induced protein aggregations
inferred← citeshttps://doi.org/10.1016/j.placenta.2012.06.006openalex-snapshot
Oxygen delivery and fetal-placental growth: Beyond a question of supply and demand?
inferred← citeshttps://doi.org/10.1016/j.placenta.2021.09.015openalex-snapshot
The effect of gestational diabetes on the expression of mitochondrial fusion proteins in placental tissue
inferred← citeshttps://doi.org/10.1016/j.prp.2026.156713openalex-snapshot
Architecture and Regulation of the PGC-1α Promoter: Implications for Metabolic Adaptation and Disease
inferred← citeshttps://doi.org/10.1016/j.resp.2013.12.007openalex-snapshot
Altered mitochondrial biogenesis and its fusion gene expression is involved in the high-altitude adaptation of rat lung
inferred← citeshttps://doi.org/10.1016/j.semcdb.2010.01.002openalex-snapshot
Mitochondrial fusion proteins: Dual regulators of morphology and metabolism
inferred← citeshttps://doi.org/10.1016/j.semcdb.2010.01.003openalex-snapshot
Organellar vs cellular control of mitochondrial dynamics
inferred← citeshttps://doi.org/10.1016/j.semcdb.2015.11.005openalex-snapshot
The emerging role of skeletal muscle oxidative metabolism as a biological target and cellular regulator of cancer-induced muscle wasting
inferred← citeshttps://doi.org/10.1016/j.taap.2018.06.031openalex-snapshot
Melatonin improves cardiac and mitochondrial function during doxorubicin-induced cardiotoxicity: A possible role for peroxisome proliferator-activated receptor gamma coactivator 1-alpha and sirtuin activity?
inferred← citeshttps://doi.org/10.1016/j.tcb.2019.08.003openalex-snapshot
The Good and the Bad of Mitochondrial Breakups
inferred← citeshttps://doi.org/10.1016/j.tem.2008.07.005openalex-snapshot
ERRα: a metabolic function for the oldest orphan
inferred← citeshttps://doi.org/10.1016/j.tem.2011.09.007openalex-snapshot
PGC-1 coactivators in the cardiovascular system
inferred← citeshttps://doi.org/10.1016/j.yfrne.2024.101122openalex-snapshot
Cholecystokinin (CCK): a neuromodulator with therapeutic potential in Alzheimer’s and Parkinson’s disease
inferred← citeshttps://doi.org/10.1016/j.ygcen.2014.04.016openalex-snapshot
Metabolic and transcriptional responses of gilthead sea bream (Sparus aurata L.) to environmental stress: New insights in fish mitochondrial phenotyping
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2009.02.020openalex-snapshot
Peroxisome proliferator-activated receptor δ regulates mitofusin 2 expression in the heart
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2014.12.001openalex-snapshot
Mitochondrial remodeling in mice with cardiomyocyte-specific lipid overload
inferred← citeshttps://doi.org/10.1021/acs.jcim.1c00662openalex-snapshot
Discovery of New Estrogen-Related Receptor α Agonists via a Combination Strategy Based on Shape Screening and Ensemble Docking
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.6b00669openalex-snapshot
Development of Therapeutics That Induce Mitochondrial Biogenesis for the Treatment of Acute and Chronic Degenerative Diseases
inferred← citeshttps://doi.org/10.1021/jacs.0c06783openalex-snapshot
Supramolecular Induction of Mitochondrial Aggregation and Fusion
inferred← citeshttps://doi.org/10.1021/jm200976sopenalex-snapshot
Identification of Pyrido[1,2-α]pyrimidine-4-ones as New Molecules Improving the Transcriptional Functions of Estrogen-Related Receptor α
inferred← citeshttps://doi.org/10.1038/ajh.2011.131openalex-snapshot
Age-Dependent Association of the Polymorphisms in the Mitochondria-Shaping Gene, OPA1, With Blood Pressure and Hypertension in Korean Population
inferred← citeshttps://doi.org/10.1038/cddis.2016.179openalex-snapshot
Junctophilin 3 expresses in pancreatic beta cells and is required for glucose-stimulated insulin secretion
inferred← citeshttps://doi.org/10.1038/emboj.2010.60openalex-snapshot
Mitochondrial fission and remodelling contributes to muscle atrophy
inferred← citeshttps://doi.org/10.1038/nm.2049openalex-snapshot
Foxo1 integrates insulin signaling with mitochondrial function in the liver
inferred← citeshttps://doi.org/10.1038/nrd4023openalex-snapshot
Pharmacological approaches to restore mitochondrial function
inferred← citeshttps://doi.org/10.1038/s12276-019-0245-zopenalex-snapshot
Nobiletin ameliorates hepatic ischemia and reperfusion injury through the activation of SIRT-1/FOXO3a-mediated autophagy and mitochondrial biogenesis
inferred← citeshttps://doi.org/10.1038/s41392-024-01756-wopenalex-snapshot
Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) family in physiological and pathophysiological process and diseases
inferred← citeshttps://doi.org/10.1038/s41401-020-00563-7openalex-snapshot
MicroRNA-214 contributes to Ang II-induced cardiac hypertrophy by targeting SIRT3 to provoke mitochondrial malfunction
inferred← citeshttps://doi.org/10.1038/s41419-018-0494-0openalex-snapshot
PGC1α promotes cholangiocarcinoma metastasis by upregulating PDHA1 and MPC1 expression to reverse the Warburg effect
inferred← citeshttps://doi.org/10.1038/s41422-018-0078-7openalex-snapshot
Skeletal muscle mitochondrial remodeling in exercise and diseases
inferred← citeshttps://doi.org/10.1038/s41467-019-11265-yopenalex-snapshot
Role of p110a subunit of PI3-kinase in skeletal muscle mitochondrial homeostasis and metabolism
inferred← citeshttps://doi.org/10.1038/s41526-018-0052-1openalex-snapshot
Sarcolab pilot study into skeletal muscle’s adaptation to long-term spaceflight
inferred← citeshttps://doi.org/10.1038/s41556-018-0133-0openalex-snapshot
Mitochondrial dynamics in adaptive and maladaptive cellular stress responses
inferred← citeshttps://doi.org/10.1038/s41580-022-00486-7openalex-snapshot
Transcriptional control of energy metabolism by nuclear receptors
inferred← citeshttps://doi.org/10.1038/s41598-025-21905-7openalex-snapshot
SIRT1/PGC-1α/Mfn2 pathway regulates mitochondrial homeostasis in VSMC to attenuate aging-related vascular calcification
inferred← citeshttps://doi.org/10.1038/sj.onc.1210986openalex-snapshot
Orphan nuclear receptor estrogen-related receptor-β suppresses in vitro and in vivo growth of prostate cancer cells via p21WAF1/CIP1 induction and as a potential therapeutic target in prostate cancer
inferred← citeshttps://doi.org/10.1039/c6ra19536aopenalex-snapshot
Computational investigation of the interaction mechanism between the estrogen related receptor α and its agonists
inferred← citeshttps://doi.org/10.1042/bcj20180617openalex-snapshot
Allosteric, transcriptional and post-translational control of mitochondrial energy metabolism
inferred← citeshttps://doi.org/10.1042/bcj20190405openalex-snapshot
Mitofusins modulate the increase in mitochondrial length, bioenergetics and secretory phenotype in therapy-induced senescent melanoma cells
inferred← citeshttps://doi.org/10.1042/bcj20210777openalex-snapshot
FoxO transcription factors in mitochondrial homeostasis
inferred← citeshttps://doi.org/10.1042/bsr20120034openalex-snapshot
Mitochondrial dysfunction in insulin resistance: differential contributions of chronic insulin and saturated fatty acid exposure in muscle cells
inferred← citeshttps://doi.org/10.1073/pnas.2018770118openalex-snapshot
TSG101 negatively regulates mitochondrial biogenesis in axons
inferred← citeshttps://doi.org/10.1074/jbc.m109.018911openalex-snapshot
PGC-1α and PGC-1Β Regulate Mitochondrial Density in Neurons
inferred← citeshttps://doi.org/10.1074/jbc.m110.125401openalex-snapshot
Estrogen-related Receptor γ Is a Key Regulator of Muscle Mitochondrial Activity and Oxidative Capacity
inferred← citeshttps://doi.org/10.1074/jbc.m110.217521openalex-snapshot
Nitric Oxide and Calcium Participate in the Fine Regulation of Mitochondrial Biogenesis in Follicular Thyroid Carcinoma Cells
inferred← citeshttps://doi.org/10.1074/jbc.m112.359174openalex-snapshot
Loss of Mitofusin 2 Promotes Endoplasmic Reticulum Stress
inferred← citeshttps://doi.org/10.1074/jbc.m113.523654openalex-snapshot
A Role for Peroxisome Proliferator-activated Receptor γ Coactivator 1 (PGC-1) in the Regulation of Cardiac Mitochondrial Phospholipid Biosynthesis
inferred← citeshttps://doi.org/10.1074/jbc.m116.728188openalex-snapshot
Increased Reliance on Muscle-based Thermogenesis upon Acute Minimization of Brown Adipose Tissue Function
inferred← citeshttps://doi.org/10.1080/14767058.2018.1532497openalex-snapshot
Maternal serum mitofusin-2 levels in patients with preeclampsia: the possible role of mitochondrial dysfunction in preeclampsia
inferred← citeshttps://doi.org/10.1089/ars.2011.4244openalex-snapshot
Adaptative Capacity of Mitochondrial Biogenesis and of Mitochondrial Dynamics in Response to Pathogenic Respiratory Chain Dysfunction
inferred← citeshttps://doi.org/10.1089/ars.2011.4357openalex-snapshot
Mitoplasticity: Adaptation Biology of the Mitochondrion to the Cellular Redox State in Physiology and Carcinogenesis
inferred← citeshttps://doi.org/10.1089/ars.2014.6208openalex-snapshot
Mitofusin 2 as a Driver That Controls Energy Metabolism and Insulin Signaling
inferred← citeshttps://doi.org/10.1089/ars.2018.7705openalex-snapshot
Mitochondrial Dysfunction: Metabolic Drivers of Pulmonary Hypertension
inferred← citeshttps://doi.org/10.1089/jir.2017.0049openalex-snapshot
Interleukin-6 Affects Aging-Related Changes of the PPARα-PGC-1α Axis in the Myocardium
inferred← citeshttps://doi.org/10.1093/cvr/cvn098openalex-snapshot
Transcriptional control of mitochondrial biogenesis: the central role of PGC-1
inferred← citeshttps://doi.org/10.1093/cvr/cvs006openalex-snapshot
The promoter activity of human Mfn2 depends on Sp1 in vascular smooth muscle cells
inferred← citeshttps://doi.org/10.1093/gerona/gls231openalex-snapshot
Decreased Levels of Proapoptotic Factors and Increased Key Regulators of Mitochondrial Biogenesis Constitute New Potential Beneficial Features of Long-lived Growth Hormone Receptor Gene-Disrupted Mice
inferred← citeshttps://doi.org/10.1093/gerona/glt107openalex-snapshot
Markers of Human Skeletal Muscle Mitochondrial Biogenesis and Quality Control: Effects of Age and Aerobic Exercise Training
inferred← citeshttps://doi.org/10.1093/hmg/ddw418openalex-snapshot
Parkin functionally interacts with PGC-1α to preserve mitochondria and protect dopaminergic neurons
inferred← citeshttps://doi.org/10.1093/hmg/ddx016openalex-snapshot
Metformin restores the mitochondrial network and reverses mitochondrial dysfunction in Down syndrome cells
inferred← citeshttps://doi.org/10.1093/jb/mvp124openalex-snapshot
Possible Role of Mitochondrial Remodelling on Cellular Triacylglycerol Accumulation
inferred← citeshttps://doi.org/10.1093/nutrit/nuaa094openalex-snapshot
Effects of (−)-epicatechin on mitochondria
inferred← citeshttps://doi.org/10.1097/med.0b013e3282c3a898openalex-snapshot
Current World Literature
inferred← citeshttps://doi.org/10.1101/2025.10.31.685870openalex-snapshot
Endoplasmic reticulum-mitochondrion disconnection promotes metabolic reprogramming and cystogenesis in polycystic kidney disease
inferred← citeshttps://doi.org/10.1101/cshperspect.a015008openalex-snapshot
Mitochondrial Biogenesis through Activation of Nuclear Signaling Proteins
inferred← citeshttps://doi.org/10.1101/gad.269894.115openalex-snapshot
Mitochondrial biogenesis and dynamics in the developing and diseased heart
inferred← citeshttps://doi.org/10.1111/ajt.16757openalex-snapshot
Augmenter of liver regeneration-mediated mitophagy protects against hepatic ischemia/reperfusion injury
inferred← citeshttps://doi.org/10.1111/apha.12690openalex-snapshot
Muscle immobilization activates mitophagy and disrupts mitochondrial dynamics in mice
inferred← citeshttps://doi.org/10.1111/apha.70020openalex-snapshot
Fam163a knockdown and mitochondrial stress in the arcuate nucleus of hypothalamus reduce AgRP neuron activity and differentially regulate mitochondrial dynamics in mice
inferred← citeshttps://doi.org/10.1111/bph.13773openalex-snapshot
Signalling mechanisms underlying doxorubicin and Nox2 NADPH oxidase‐induced cardiomyopathy: involvement of mitofusin‐2
inferred← citeshttps://doi.org/10.1111/brv.12378openalex-snapshot
Structure, function, and regulation of mitofusin‐2 in health and disease
inferred← citeshttps://doi.org/10.1111/cns.70530openalex-snapshot
Osteocalcin Ameliorates CUMS ‐Induced Depressive‐Like Behaviors by Reducing Mitochondrial Damage in Hippocampal Neurons
inferred← citeshttps://doi.org/10.1111/febs.13334openalex-snapshot
Shaping of interphase chromosomes by the microtubule network
inferred← citeshttps://doi.org/10.1111/febs.16283openalex-snapshot
Cardiac fibroblasts display endurance to ischemia, high ROS control and elevated respiration regulated by the JAK2/STAT pathway
inferred← citeshttps://doi.org/10.1111/j.1463-1326.2010.01267.xopenalex-snapshot
Impact of nitric oxide on metabolism in health and age‐related disease
inferred← citeshttps://doi.org/10.1111/j.1529-8027.2008.00196.xopenalex-snapshot
Diabetes mellitus exacerbates motor and sensory impairment in CMT1A
inferred← citeshttps://doi.org/10.1111/j.1749-6632.2010.05618.xopenalex-snapshot
Redefining the role of mitochondria in exercise: a dynamic remodeling
inferred← citeshttps://doi.org/10.1111/j.2040-1124.2010.00047.xopenalex-snapshot
Mitochondrial metabolism and diabetes
inferred← citeshttps://doi.org/10.1111/jcmm.12320openalex-snapshot
Tumour necrosis factor‐α promotes liver ischaemia‐reperfusion injury through the PGC ‐1α/Mfn2 pathway
inferred← citeshttps://doi.org/10.1113/ep091731openalex-snapshot
Exercise training to preserve vitality capacity in ageing
inferred← citeshttps://doi.org/10.1113/jp274148openalex-snapshot
Structure and function of human muscle fibres and muscle proteome in physically active older men
inferred← citeshttps://doi.org/10.1113/jphysiol.2014.286740openalex-snapshot
The role of alterations in mitochondrial dynamics and PGC‐1α over‐expression in fast muscle atrophy following hindlimb unloading
inferred← citeshttps://doi.org/10.1124/jpet.118.252833openalex-snapshot
Proximal Tubule β2-Adrenergic Receptor Mediates Formoterol-Induced Recovery of Mitochondrial and Renal Function after Ischemia-Reperfusion Injury
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