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The mechanism of the anti-inflammatory effect of Oldenlandia diffusa on arthritis model rats: a quantitative proteomic and network pharmacologic study

https://doi.org/10.21037/atm-22-3678
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/jcla.24133openalex-snapshot
iTRAQ‐based proteomic analysis of differentially expressed proteins in sera of seronegative and seropositive rheumatoid arthritis patients
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Biomarker identification and pathway analysis of rheumatoid arthritis based on metabolomics in combination with ingenuity pathway analysis
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iTRAQ Data Interpretation
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Anti-inflammatory and Hepatoprotective Effects of Quercetin in an Experimental Model of Rheumatoid Arthritis
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Flavonoid quercetin–methotrexate combination inhibits inflammatory mediators and matrix metalloproteinase expression, providing protection to joints in collagen-induced arthritis
inferredcites →https://doi.org/10.1007/s11010-017-3003-3openalex-snapshot
MicroRNA-192 suppresses cell proliferation and induces apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes by downregulating caveolin 1
inferredcites →https://doi.org/10.1007/s11033-020-05909-2openalex-snapshot
Pro-inflammatory cytokine response pre-dominates immuno-genetic pathway in development of rheumatoid arthritis
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Network Pharmacology in Research of Chinese Medicine Formula: Methodology, Application and Prospective
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Synchronous Investigation of the Mechanism and Substance Basis of Tripterygium Glycosides Tablets on Anti-rheumatoid Arthritis and Hepatotoxicity
inferredcites →https://doi.org/10.1016/j.abb.2019.06.007openalex-snapshot
Quercetin suppressed NADPH oxidase-derived oxidative stress via heme oxygenase-1 induction in macrophages
inferredcites →https://doi.org/10.1016/j.atherosclerosis.2015.05.038openalex-snapshot
The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis
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GRK2-mediated receptor phosphorylation and Mdm2-mediated β-arrestin2 ubiquitination drive clathrin-mediated endocytosis of G protein-coupled receptors
inferredcites →https://doi.org/10.1016/j.berh.2019.01.006openalex-snapshot
MMP3 is a reliable marker for disease activity, radiological monitoring, disease outcome predictability, and therapeutic response in rheumatoid arthritis
inferredcites →https://doi.org/10.1016/j.biopha.2017.03.026openalex-snapshot
Therapeutic effect of quercetin in collagen-induced arthritis
inferredcites →https://doi.org/10.1016/j.cca.2020.11.020openalex-snapshot
Caveolin-1 in autophagy: A potential therapeutic target in atherosclerosis
inferredcites →https://doi.org/10.1016/j.ejphar.2015.02.039openalex-snapshot
Berberine inhibits Chlamydia pneumoniae infection-induced vascular smooth muscle cell migration through downregulating MMP3 and MMP9 via PI3K
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Epigallocatechin-3-gallate, an active ingredient of Traditional Chinese Medicines, inhibits the 3CLpro activity of SARS-CoV-2
inferredcites →https://doi.org/10.1016/j.intimp.2021.108042openalex-snapshot
Micro RNAs 26b, 20a inversely correlate with GSK-3 β/NF-κB/NLRP-3 pathway to highlight the additive promising effects of atorvastatin and quercetin in experimental induced arthritis
inferredcites →https://doi.org/10.1016/j.jep.2020.112913openalex-snapshot
Total glucosides of paeony: A review of its phytochemistry, role in autoimmune diseases, and mechanisms of action
inferredcites →https://doi.org/10.1016/j.jnutbio.2020.108454openalex-snapshot
Quercetin alleviates rheumatoid arthritis by inhibiting neutrophil inflammatory activities
inferredcites →https://doi.org/10.1016/j.jot.2021.01.003openalex-snapshot
Treatment of collagen-induced arthritis rat model by using Notch signalling inhibitor
inferredcites →https://doi.org/10.1016/j.omto.2021.07.013openalex-snapshot
A novel protein-drug conjugate, SSH20, demonstrates significant efficacy in caveolin-1-expressing tumors
inferredcites →https://doi.org/10.1016/j.phymed.2021.153543openalex-snapshot
Network pharmacology to explore the anti-inflammatory mechanism of Xuebijing in the treatment of sepsis
inferredcites →https://doi.org/10.1016/j.talanta.2021.122705openalex-snapshot
Simultaneous determination of CXCL7 chemokine and MMP3 metalloproteinase as biomarkers for rheumatoid arthritis
inferredcites →https://doi.org/10.1016/j.tips.2021.11.004openalex-snapshot
Network pharmacology: curing causal mechanisms instead of treating symptoms
inferredcites →https://doi.org/10.1016/s1875-5364(21)60001-8openalex-snapshot
TCM network pharmacology: A new trend towards combining computational, experimental and clinical approaches
inferredcites →https://doi.org/10.1021/acsbiomaterials.9b01331openalex-snapshot
Caveolin Elastin-Like Polypeptide Fusions Mediate Temperature-Dependent Assembly of Caveolar Microdomains
inferredcites →https://doi.org/10.1021/acsomega.1c06131openalex-snapshot
Insights into Anti-Inflammatory Activity and Internalization Pathway of Onion Peel-Derived Gold Nano Bioconjugates in RAW 264.7 Macrophages
inferredcites →https://doi.org/10.1038/s41598-021-85840-zopenalex-snapshot
Quercetin can reduce viral RNA level of O’nyong-nyong virus and resulting innate immune cytokine responses in cultured human synovial fibroblasts
inferredcites →https://doi.org/10.1074/jbc.m609157200openalex-snapshot
Caveolin-1 Triggers T-cell Activation via CD26 in Association with CARMA1
inferredcites →https://doi.org/10.1080/13880209.2020.1817103openalex-snapshot
Integrated meta-analysis, network pharmacology, and molecular docking to investigate the efficacy and potential pharmacological mechanism of Kai-Xin-San on Alzheimer's disease
inferredcites →https://doi.org/10.1080/14786419.2021.1974434openalex-snapshot
Chemical constituents fromOldenlandia diffusaand their cytotoxic effects on human cancer cell lines
inferredcites →https://doi.org/10.1155/2018/2498576openalex-snapshot
Caveolin-1-Knockout Mouse as a Model of Inflammatory Diseases
inferredcites →https://doi.org/10.1155/2018/5198594openalex-snapshot
Anti‐Inflammatory Effects of p‐Coumaric Acid, a Natural Compound of Oldenlandia diffusa, on Arthritis Model Rats
inferredcites →https://doi.org/10.1155/2019/9013169openalex-snapshot
Resveratrol Inhibits MMP3 and MMP9 Expression and Secretion by Suppressing TLR4/NF-κB/STAT3 Activation in Ox-LDL-Treated HUVECs
inferredcites →https://doi.org/10.1155/2020/1646905openalex-snapshot
Applications of Network Pharmacology in Traditional Chinese Medicine Research
inferredcites →https://doi.org/10.1155/2020/6869856openalex-snapshot
Avβ3 Single-Stranded DNA Aptamer Attenuates Vascular Smooth Muscle Cell Proliferation and Migration via Ras-PI3K/MAPK Pathway
inferredcites →https://doi.org/10.1155/2021/5858393openalex-snapshot
Evodiae fructus Extract Inhibits Interleukin-1β-Induced MMP-1, MMP-3, and Inflammatory Cytokine Expression by Suppressing the Activation of MAPK and STAT-3 in Human Gingival Fibroblasts In Vitro
inferredcites →https://doi.org/10.1210/endocr/bqac036openalex-snapshot
Vasoinhibin is Generated and Promotes Inflammation in Mild Antigen-induced Arthritis
inferredcites →https://doi.org/10.1272/jnms.jnms.2021_88-501openalex-snapshot
Effect of Ethanol on Gene Expression of Beating Neonatal Rat Cardiomyocytes - Further Research with Ingenuity Pathway Analysis Software -
inferredcites →https://doi.org/10.15586/qas.v14i1.970openalex-snapshot
The effects of Oldenlandia diffusa water extract on glucose metabolism and inflammation level in rats with streptozotocin-induced gestational diabetes mellitus
inferredcites →https://doi.org/10.17219/acem/75611openalex-snapshot
The effect of caveolin-1 knockdown on interleukin-1β-induced chemokine (C-C motif) ligand 2 expression in synovial fluid-derived fibroblast-like synoviocytes from patients with rheumatoid arthritis
inferredcites →https://doi.org/10.18502/ijaai.v21i1.8612openalex-snapshot
Evaluating Mannuronic Acid Effect on Gene Expression Profile of Inflammatory Mediators in Rheumatoid Arthritis Patients
inferredcites →https://doi.org/10.21037/atm-22-3678openalex-snapshot
The mechanism of the anti-inflammatory effect of Oldenlandia diffusa on arthritis model rats: a quantitative proteomic and network pharmacologic study
inferredcites →https://doi.org/10.2147/jir.s340351openalex-snapshot
iTRAQ and PRM-Based Proteomic Analysis Provides New Insights into Mechanisms of Response to Triple Therapy in Patients with Rheumatoid Arthritis
inferredcites →https://doi.org/10.3164/jcbn.16-2openalex-snapshot
Effect of quercetin and its metabolite on caveolin-1 expression induced by oxidized LDL and lysophosphatidylcholine in endothelial cells
inferredcites →https://doi.org/10.3164/jcbn.20-190openalex-snapshot
Suppressive effects of quercetin on hydrogen peroxide-induced caveolin-1 phosphorylation in endothelial cells
inferredcites →https://doi.org/10.3389/fimmu.2019.03129openalex-snapshot
Non-coding RNAs in Rheumatoid Arthritis: From Bench to Bedside
inferredcites →https://doi.org/10.3389/fnut.2021.735742openalex-snapshot
The Potential Effects of Dielectric Barrier Discharge Plasma on the Extraction Efficiency of Bioactive Compounds in Radix Paeoniae Alba
inferredcites →https://doi.org/10.3389/fphar.2017.00818openalex-snapshot
Development of the Digital Arthritis Index, a Novel Metric to Measure Disease Parameters in a Rat Model of Rheumatoid Arthritis
inferredcites →https://doi.org/10.3390/molecules26216570openalex-snapshot
Polyphenols Targeting MAPK Mediated Oxidative Stress and Inflammation in Rheumatoid Arthritis
inferredcites →https://doi.org/10.3892/etm.2021.10371openalex-snapshot
Applicability and implementation of the collagen‑induced arthritis mouse model, including protocols (Review)
inferredcites →https://doi.org/10.3892/etm.2021.10695openalex-snapshot
Quercetin suppresses inflammatory cytokine production in rheumatoid arthritis fibroblast‑like synoviocytes

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4756338openalex-extracted
inferred← citeshttps://doi.org/10.1007/s00210-023-02756-3openalex-snapshot
Phytochemistry, pharmacology, and medical uses of Oldenlandia (family Rubaceae): a review
inferred← citeshttps://doi.org/10.1016/j.indcrop.2024.119952openalex-snapshot
Integrated strategy of mass spectrometry imaging and LC/MS-based GNPS for spatial characterization of alkaloids from Menispermi Rhizoma and study on potential anti-inflammatory mechanism by network pharmacology and molecular docking
inferred← citeshttps://doi.org/10.1016/j.jep.2023.116744openalex-snapshot
Extracts of Oldenlandia diffusa protects chondrocytes via inhibiting apoptosis and associated inflammatory response in osteoarthritis
inferred← citeshttps://doi.org/10.3389/fphar.2023.1243820openalex-snapshot
Therapeutic potential of Coptis chinensis for arthritis with underlying mechanisms
inferred← citeshttps://doi.org/10.46242/jstiuh.v74i2.5178openalex-snapshot
ANTIOXIDANT AND IMMUNOMODULATORY EFFECTS OF ETHANOL EXTRACT FROM Oldenlandia capitellata Kuntze LEAVES IN INDOMETHACIN-INDUCED GASTRIC INFLAMMATION IN MICE
inferred← citeshttps://doi.org/10.7150/jca.85517openalex-snapshot
Network pharmacology and bioinformatics were used to construct a prognostic model and immunoassay of core target genes in the combination of quercetin and kaempferol in the treatment of colorectal cancer
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