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In Vivo, In Situ and Ex Vivo Comparison of Porcine Skin for Microprojection Array Penetration Depth, Delivery Efficiency and Elastic Modulus Assessment

https://doi.org/10.2139/ssrn.3991474
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Site‐Selectively Coated, Densely‐Packed Microprojection Array Patches for Targeted Delivery of Vaccines to Skin
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Development of In Vivo Constitutive Models for Liver: Application to Surgical Simulation
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Dynamic mechanical response of brain tissue in indentation in vivo, in situ and in vitro
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The hyperelastic and failure behaviors of skin in relation to the dynamic application of microscopic penetrators in a murine model
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The mechanical properties of the skin epidermis in relation to targeted gene and drug delivery
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The effect of strain rate on the precision of penetration of short densely-packed microprojection array patches coated with vaccine
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Elastic modulus and viscoelastic properties of full thickness skin characterised at micro scales
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Dynamic application of microprojection arrays to skin induces circulating protein extravasation for enhanced biomarker capture and detection
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Rapid and selective sampling of IgG from skin in less than 1 min using a high surface area wearable immunoassay patch
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Biomechanical properties of the forefoot plantar soft tissue as measured by an optical coherence tomography-based air-jet indentation system and tissue ultrasound palpation system
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Are in vivo and in situ brain tissues mechanically similar?
inferredcites →https://doi.org/10.1016/j.jbiomech.2004.01.032openalex-extracted
Intradermal ballistic delivery of micro-particles into excised human skin for pharmaceutical applications
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Effects of perfusion on the viscoelastic characteristics of liver
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Mechanical properties of porcine brain tissue in vivo and ex vivo estimated by MR elastography
inferredcites →https://doi.org/10.1016/j.jconrel.2009.06.029openalex-extracted
Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin
inferredcites →https://doi.org/10.1016/j.jconrel.2011.10.026openalex-extracted
Rapid kinetics to peak serum antibodies is achieved following influenza vaccination by dry-coated densely packed microprojections to skin
inferredcites →https://doi.org/10.1016/j.jconrel.2012.07.024openalex-extracted
Induction of potent CD8+ T cell responses through the delivery of subunit protein vaccines to skin antigen-presenting cells using densely packed microprojection arrays
inferredcites →https://doi.org/10.1016/j.jconrel.2012.12.010openalex-extracted
Depth-resolved characterization of diffusion properties within and across minimally-perturbed skin layers
inferredcites →https://doi.org/10.1016/j.jconrel.2016.06.045openalex-extracted
Influenza nucleoprotein DNA vaccination by a skin targeted, dry coated, densely packed microprojection array (Nanopatch) induces potent antibody and CD8 + T cell responses
inferredcites →https://doi.org/10.1016/j.jconrel.2019.05.024openalex-extracted
Cellular metabolism and pore lifetime of human skin following microprojection array mediation
inferredcites →https://doi.org/10.1016/j.medengphy.2014.02.022openalex-extracted
Optical tracking of local surface wave for skin viscoelasticity
inferredcites →https://doi.org/10.1016/j.mjafi.2014.08.005openalex-extracted
Influence of skin-to-muscle and muscle-to-bone thickness on depth of needle penetration in adults at the deltoid intramuscular injection site
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Critical relative indentation depth in carbon based thin films
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Comparison of the surface wave method and the indentation method for measuring the elasticity of gelatin phantoms of different concentrations
inferredcites →https://doi.org/10.1016/j.vaccine.2018.05.053openalex-extracted
Safety, tolerability, acceptability and immunogenicity of an influenza vaccine delivered to human skin by a novel high-density microprojection array patch (Nanopatch™)
inferredcites →https://doi.org/10.1038/s41598-017-13011-0openalex-extracted
High-density microprojection array delivery to rat skin of low doses of trivalent inactivated poliovirus vaccine elicits potent neutralising antibody responses
inferredcites →https://doi.org/10.1038/s41598-017-15830-7openalex-extracted
Allometric scaling of skin thickness, elasticity, viscoelasticity to mass for micro-medical device translation: from mice, rats, rabbits, pigs to humans
inferredcites →https://doi.org/10.1038/s41598-018-36009-8openalex-extracted
Space- and time-resolved investigation on diffusion kinetics of human skin following macromolecule delivery by microneedle arrays
inferredcites →https://doi.org/10.1038/srep22094openalex-extracted
Inactivated poliovirus type 2 vaccine delivered to rat skin via high density microprojection array elicits potent neutralising antibody responses
inferredcites →https://doi.org/10.1038/srep27217openalex-extracted
The changing shape of vaccination: improving immune responses through geometrical variations of a microdevice for immunization
inferredcites →https://doi.org/10.1039/c2ra20153dopenalex-extracted
High density and high aspect ratio solid micro-nanoprojection arrays for targeted skin vaccine delivery and specific antibody extraction
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Carcass electrical stimulation to prevent cold shortening toughness in beef
inferredcites →https://doi.org/10.1080/10255840290032658openalex-extracted
The Effect of Perfusion on Soft Tissue Mechanical Properties: A Computational Model
inferredcites →https://doi.org/10.1080/10255842.2011.596481openalex-extracted
Quantifying the mechanical properties of human skin to optimise future microneedle device design
inferredcites →https://doi.org/10.1088/0957-0233/20/1/015805openalex-extracted
An optical coherence tomography (OCT)-based air jet indentation system for measuring the mechanical properties of soft tissues
inferredcites →https://doi.org/10.1097/00004647-199804000-00011openalex-extracted
Absolute Cerebral Blood Flow and Blood Volume Measured by Magnetic Resonance Imaging Bolus Tracking: Comparison with Positron Emission Tomography Values
inferredcites →https://doi.org/10.1098/rsif.2011.0583openalex-extracted
Determining elastic properties of skin by measuring surface waves from an impulse mechanical stimulus using phase-sensitive optical coherence tomography
inferredcites →https://doi.org/10.1111/j.0022-202x.2004.22320.xopenalex-extracted
Effects of Relative Humidity and Ambient Temperature on the Ballistic Delivery of Micro-Particles to Excised Porcine Skin
inferredcites →https://doi.org/10.1111/j.1600-0846.2006.00179.xopenalex-extracted
Porcine ear skin: an in vitro model for human skin
inferredcites →https://doi.org/10.1117/1.1803843openalex-extracted
Low-frequency surface wave propagation and the viscoelastic behavior of porcine skin
inferredcites →https://doi.org/10.1117/12.883254openalex-extracted
Measuring soft tissue elasticity by monitoring surface acoustic waves using image plane digital holography
inferredcites →https://doi.org/10.1121/1.2785045openalex-extracted
Estimation of tissue’s elasticity with surface wave speed
inferredcites →https://doi.org/10.1177/0300985816629720openalex-extracted
Postmortem Changes in Animal Carcasses and Estimation of the Postmortem Interval
inferredcites →https://doi.org/10.1371/journal.pone.0031203openalex-extracted
The Effect of Surface Wave Propagation on Neural Responses to Vibration in Primate Glabrous Skin
inferredcites →https://doi.org/10.1371/journal.pone.0067888openalex-extracted
Dry-Coated Live Viral Vector Vaccines Delivered by Nanopatch Microprojections Retain Long-Term Thermostability and Induce Transgene-Specific T Cell Responses in Mice
inferredcites →https://doi.org/10.14264/uql.2018.594openalex-extracted
The key biomechanics of the skin for the translation of microscale medical devices from animal models to humans
inferredcites →https://doi.org/10.1586/17434440.3.1.1openalex-extracted
Microneedle array technology: the time is right but is the science ready?
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A survey of the use of live animals, cadavers, inanimate models, and computers in teaching veterinary surgery
inferredcites →https://doi.org/10.3233/978-1-60750-938-7-26openalex-extracted
In-Vivo and In-Situ Compressive Properties of Porcine Abdominal Soft Tissues
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Egg white proteins and their potential use in food processing or as nutraceutical and pharmaceutical agents—A review
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